{"title":"Truths and Myths of Radiotherapy","authors":"F. Lorenzo","doi":"10.19080/ctoij.2019.13.555875","DOIUrl":"https://doi.org/10.19080/ctoij.2019.13.555875","url":null,"abstract":"","PeriodicalId":9575,"journal":{"name":"Cancer Therapy & Oncology International Journal","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82544967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Novel Therapeutic Strategies in Development for Myelodysplastic Syndromes","authors":"N. Hamed","doi":"10.19080/ctoij.2019.13.555874","DOIUrl":"https://doi.org/10.19080/ctoij.2019.13.555874","url":null,"abstract":"","PeriodicalId":9575,"journal":{"name":"Cancer Therapy & Oncology International Journal","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80449301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Re-Formulated Immuno-Editing as Agonist and Permissive Elements in Establishment of Foci of Carcinogenesis","authors":"lawrence M Agius","doi":"10.19080/ctoij.2019.14.555877","DOIUrl":"https://doi.org/10.19080/ctoij.2019.14.555877","url":null,"abstract":"Diffusional phenomena of paracrine and autocrine reconstitution in a focus of initial carcinogenesis include the derivative phenomenon of immuno-editing in the induced loss of immuno-surveillance. Immuno-surveillance is attempted definition of the constitutional identification of an injury that relates intimately with inflammatory response and interactivity. In terms further conforming to an injury in chronic inflammation, the responsive elements at reconstitution fail as a result of loss an antigenicity of individual tumor cells. Recapitulation of such agonist action is further promoted as permissive elemental injury that transforms such permissiveness to the emergence of tumor cells that evade the immune system. Characterization is injury-provoking within the systems of complex interactivity as modulated by multiple molecular events at attempted reconstitution.","PeriodicalId":9575,"journal":{"name":"Cancer Therapy & Oncology International Journal","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84705600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Short Review on Treatment of Superficial Bladder Cancer (Ta, Tis, T1)","authors":"Phalguni Gupta","doi":"10.19080/ctoij.2019.14.555876","DOIUrl":"https://doi.org/10.19080/ctoij.2019.14.555876","url":null,"abstract":"At presentation, 70% of patients with bladder cancer have superficial disease, out of which, approximately 15% to 20% will progress to stage T2 disease or greater over time. Following initial therapy, 50% to 70% of those presenting with Ta or T1 disease will have a recurrence. Low-grade tumors (grade I or II) and low-stage (Ta) disease tend to have a lower recurrence rate at about 50% and a 5% progression rate, whereas highrisk disease (grade III, T1 associated with CIS, and multifocal disease) has a 70% recurrence rate and a 30% progression rate to stage T2 disease or greater disease. Less than 5% of patients with superficial bladder cancer will develop metastatic disease without developing evidence of muscularis propria invasion (stage T2 disease or greater) of the primary lesion.","PeriodicalId":9575,"journal":{"name":"Cancer Therapy & Oncology International Journal","volume":"100 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76465860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinically, Radiologically and Biochemically Metastatic Cancer Prostate: could be treated without Biopsy? A Clinical Case Study","authors":"Bader A Abdelmaksoud","doi":"10.19080/ctoij.2019.13.555873","DOIUrl":"https://doi.org/10.19080/ctoij.2019.13.555873","url":null,"abstract":"","PeriodicalId":9575,"journal":{"name":"Cancer Therapy & Oncology International Journal","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90920296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Promoter Hypermethylation of Apoptotic genes in Oral Squamous Cell Carcinoma","authors":"A. kumar Jha","doi":"10.19080/ctoij.2019.13.555872","DOIUrl":"https://doi.org/10.19080/ctoij.2019.13.555872","url":null,"abstract":"Cancer stands among the foremost advanced human diseases with multiple levels of regulation. Despite the numerous progress that has been created in basic and clinical analysis, the incidence associated mortality rates related to malignant pathologies are still at high levels with an expected raised rate within the next fifteen years Irimie et al. [1]. The sixth most typical malignancy that has been found is Head and Neck cancer, wherever carcinoma represents the foremost frequent subtype inside this spectrum Irimie et al. [2], Hema et al. [3]. Also, Oral Squamous Cell Carcinoma (OSCC) accounts for roughly ninetieth of the oral subtype, being far and away the foremost common sort of malignancy inside the mouth Parkin et al. [4], Stewart et al. [5]. Apoptosis is that one pathway that could lead the elimination of oncogenic cells. Apoptosis can be explained as a process in which natural death of cells is initiated to maintain the cellular homeostasis. A variety of changes are done in the structure of cells by apoptotic proteins that eliminate the cell out of body. In this mechanism events occurs which result into formation of cascades that encounters the already anteceding cells leading them to demise, also known as “programmed cell death”, Elmore [6], Hervouet et al. [7]. The initiation and maturation of oral carcinoma caused by total of genetic changes combined with environmental risk factors (special mention to alcohol and tobacco use however various viral infectious agents and persistent inflammations) cause changes within the pursuit of cancer causing genes i.e., oncogenes and tumour suppressor genes Perez et al. [8], Irimie et al. [9].","PeriodicalId":9575,"journal":{"name":"Cancer Therapy & Oncology International Journal","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80404559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cutaneous Metastases of Urothelial Carcinoma: Mini Review","authors":"A. Shvero","doi":"10.19080/ctoij.2019.13.555870","DOIUrl":"https://doi.org/10.19080/ctoij.2019.13.555870","url":null,"abstract":"","PeriodicalId":9575,"journal":{"name":"Cancer Therapy & Oncology International Journal","volume":"93 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91544283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Discussions on Changes in Gastric Lymph Drainage in Malignant Gastric Pathology in Terms of Intraoperative Lymphography","authors":"Kiss Lorant","doi":"10.19080/ctoij.2019.13.555869","DOIUrl":"https://doi.org/10.19080/ctoij.2019.13.555869","url":null,"abstract":"","PeriodicalId":9575,"journal":{"name":"Cancer Therapy & Oncology International Journal","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74413073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Prospective Study to Compare Concomitant Boost Radiotherapy and Conventional Radiotherapy in Oral Cavity Cancer","authors":"Yadav Raj Kumar","doi":"10.19080/ctoij.2019.13.555866","DOIUrl":"https://doi.org/10.19080/ctoij.2019.13.555866","url":null,"abstract":"","PeriodicalId":9575,"journal":{"name":"Cancer Therapy & Oncology International Journal","volume":"78 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83318798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}