Canadian Journal of Cardiology最新文献

{"title":"P092 CARDIAC ICU FAMILY ENGAGEMENT AND PATIENT OUTCOMES","authors":"J. Kandiah, M. Goldfarb","doi":"10.1016/j.cjca.2025.08.060","DOIUrl":"10.1016/j.cjca.2025.08.060","url":null,"abstract":"","PeriodicalId":9555,"journal":{"name":"Canadian Journal of Cardiology","volume":"41 10","pages":"Pages S54-S55"},"PeriodicalIF":5.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145189830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"P093 EXPLORING THE REAL-WORLD EXPERIENCE IN STEMI TREATMENT WITH “RESCUE PCI” IN ATLANTIC CANADA","authors":"M. MacKinnon, D. McKee, C. White, B. McGrath, J. MacLeod, J. Legare","doi":"10.1016/j.cjca.2025.08.061","DOIUrl":"10.1016/j.cjca.2025.08.061","url":null,"abstract":"","PeriodicalId":9555,"journal":{"name":"Canadian Journal of Cardiology","volume":"41 10","pages":"Page S55"},"PeriodicalIF":5.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145189831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CCS Page– Board of Directors","authors":"","doi":"10.1016/S0828-282X(25)01030-X","DOIUrl":"10.1016/S0828-282X(25)01030-X","url":null,"abstract":"","PeriodicalId":9555,"journal":{"name":"Canadian Journal of Cardiology","volume":"41 10","pages":"Page A1"},"PeriodicalIF":5.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145189910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Supra-annular Prosthesis Anchoring in Bicuspid Aortic Valve: Evidence in Large Annuli Exceeding the Device Sizing Chart Range","authors":"Barbara Bellini MD , Vittorio Romano RT , Gianmarco Iannopollo MD , Greca Zanda MD , Ciro Vella MD , Luca Angelo Ferri MD , Filippo Russo MD , Marco Bruno Ancona MD , Antonio Esposito MD , Matteo Montorfano MD","doi":"10.1016/j.cjca.2025.04.027","DOIUrl":"10.1016/j.cjca.2025.04.027","url":null,"abstract":"","PeriodicalId":9555,"journal":{"name":"Canadian Journal of Cardiology","volume":"41 10","pages":"Pages 1896-1898"},"PeriodicalIF":5.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143976659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Strategies to Identify Echocardiogram Complexity to Support Learning Echocardiogram Interpretation","authors":"Thomas C. Raissi MD , Thivya Sivarajan MSc , Aws Almufleh MBBS, MPH , Annabel Chen-Tournoux MD , Robin Ducas MD , Parvathy Nair MD , Matthew Sibbald MD, MHPE, PhD, FRCPC , Graham C. Wong MD, MPH , Samuel C.B. Siu MD, SM, MBA , Sarah Blissett MD, MHPE","doi":"10.1016/j.cjca.2025.04.025","DOIUrl":"10.1016/j.cjca.2025.04.025","url":null,"abstract":"","PeriodicalId":9555,"journal":{"name":"Canadian Journal of Cardiology","volume":"41 10","pages":"Pages 1967-1970"},"PeriodicalIF":5.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143970714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Heart Function, Valvular Hemodynamics, and Early-term Outcomes of Possible Thrombosis in Self-Expanding Transcatheter Pulmonary Valve","authors":"Wenhao Zhu MD ,&nbsp;Zhiyuan Xia PhD ,&nbsp;Jiaxin Xie MD ,&nbsp;Junyi Wan MD ,&nbsp;Zhihui Hou MD ,&nbsp;Liang Xu MD ,&nbsp;Haiyue Xie MD ,&nbsp;Yihang Li PhD ,&nbsp;Jingnan Zhang PhD ,&nbsp;Yu Han MD ,&nbsp;Xiangbin Pan MD ,&nbsp;Gary Tse PhD ,&nbsp;Jeffrey Shi Kai Chan MBChB, MPH ,&nbsp;Fang Fang MD, PhD ,&nbsp;Gejun Zhang MD","doi":"10.1016/j.cjca.2025.04.021","DOIUrl":"10.1016/j.cjca.2025.04.021","url":null,"abstract":"<div><h3>Background</h3><div>The clinical implications of hypoattenuating leaflet thickening (HALT) and its potential link to thrombosis detected via computed tomography (CT) scans in post transcatheter pulmonary valve replacement (TPVR) patients are unknown. In this study we aimed to explore the prevalence, heart function, valvular hemodynamics, and early outcomes of HALT after TPVR.</div></div><div><h3>Methods</h3><div>We studied 64 of 76 consecutive multicentre patients who underwent TPVR, with the implantation of a Venus-P device (Venus MedTech Inc, Hangzhou, China). CT characteristics within a year, echocardiographic data, and early-term clinical end points were analyzed in patients with and without HALT.</div></div><div><h3>Results</h3><div>CT scans revealed HALT in 28 patients (56%) and reduced leaflet motion in 11 patients (20.8%) within 1 year (median interval, 184 [interquartile range, 104-214] days). HALT patients exhibited a lower percentage of normal tricuspid annular plane systolic excursion at the CT scan time (58.3% vs 73.7%; <em>P</em> = 0.020), although valvular hemodynamics and clinical end points were similar. Older age at intervention (odds ratio, 1.05; 95% confidence interval, 1.01-1.09) and larger body mass index (odds ratio, 1.17; 95% confidence interval, 1.01-1.36) were associated with HALT, whereas the use of anticoagulation was not identified as a protective factor. The HALT severity was positively correlated with the degree of leaflet motion (<em>r</em> = 0.67 and 0.69, respectively).</div></div><div><h3>Conclusions</h3><div>HALT was highly prevalent, although it was subclinical. Early follow-up showed uneventful valvular hemodynamics and clinical outcomes. However, the HALT group exhibited suboptimal right ventricular function during CT scans, with older age and higher body mass index linked to this issue.</div></div>","PeriodicalId":9555,"journal":{"name":"Canadian Journal of Cardiology","volume":"41 10","pages":"Pages 1885-1895"},"PeriodicalIF":5.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143985200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reassessing Cardiovascular Risk in Patients With Peripheral Artery Disease Undergoing Myocardial Perfusion Imaging","authors":"Kaiming Wang MSc ,&nbsp;Tali Sharir MD ,&nbsp;M. Timothy Hauser MD ,&nbsp;Sharmila Dorbala MD, MPH ,&nbsp;Marcelo Di Carli MD ,&nbsp;Mathews B. Fish MD ,&nbsp;Terrence D. Ruddy MD ,&nbsp;Timothy Bateman MD ,&nbsp;Andrew J. Einstein MD, PhD ,&nbsp;Philipp A. Kaufmann MD ,&nbsp;Edward J. Miller MD, PhD ,&nbsp;Albert J. Sinusas MD ,&nbsp;Wanda Acampa MD, PhD ,&nbsp;Julian Halcox MD ,&nbsp;Monica Martins MSc ,&nbsp;Joanna X. Liang MSc ,&nbsp;Valerie Builoff BSc ,&nbsp;Damini Dey PhD ,&nbsp;Daniel S. Berman MD ,&nbsp;Robert J.H. Miller MD ,&nbsp;Piotr J. Slomka PhD","doi":"10.1016/j.cjca.2025.05.002","DOIUrl":"10.1016/j.cjca.2025.05.002","url":null,"abstract":"<div><h3>Background</h3><div>Coronary artery disease (CAD) and peripheral artery disease (PAD) are often regarded as analogous risk factors for major adverse cardiovascular events (MACE), given their shared pathophysiology. We aimed to investigate whether the elevated MACE risk in PAD is driven by myocardial perfusion abnormalities or through other PAD-specific mediators.</div></div><div><h3>Methods</h3><div>We analyzed 45,252 patients from an international, multicentre registry who underwent SPECT myocardial perfusion imaging, excluding those with early coronary revascularization (&lt; 90 days). Myocardial perfusion abnormalities were quantified using total perfusion deficit (TPD). MACE was defined as all-cause mortality, unstable angina admission, myocardial infarction, or late coronary revascularization. PAD was defined using questionnaires or review of electronic medical records. Propensity-score matching was used to select balanced groups of patients with and without PAD.</div></div><div><h3>Results</h3><div>During a median follow-up of 3.6 years (interquartile range [IQR]: 2.6-4.8 years), 5932 patients (13.7%) experienced at least 1 MACE. Compared with patients with neither disease, isolated history of CAD (adjusted hazard ratio [aHR], 1.92; 95% confidence interval [CI], 1.80-2.05) conferred a similar MACE risk as concomitant history of CAD and PAD (aHR, 1.57; 95% CI, 1.44-1.71) and greater risk than isolated history of PAD (aHR, 1.20; 95% CI, 1.09-1.32; <em>P</em> &lt; 0.001). After propensity-score matching, history of PAD alone was not independently associated with increased MACE risk (<em>P</em> = 0.064).</div></div><div><h3>Conclusions</h3><div>Although patients with PAD often have concomitant CAD and greater myocardial perfusion abnormalities, PAD itself was not linked to higher risk of MACE after adjusting for these factors. These findings highlight the importance of assessing myocardial ischemic burden in PAD for risk stratification and prompt initiation of disease-modifying therapies.</div></div>","PeriodicalId":9555,"journal":{"name":"Canadian Journal of Cardiology","volume":"41 10","pages":"Pages 1936-1945"},"PeriodicalIF":5.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Automatically Derived Unipolar Low-Voltage-Area Burden for Predicting Atrial Fibrillation Ablation Outcomes","authors":"Xiuyu Qi MD,&nbsp;Mingfang Li MD,&nbsp;Hongwu Chen MD,&nbsp;Gang Yang MD,&nbsp;Hailei Liu MD,&nbsp;Zidun Wang MD,&nbsp;Xiaohong Jiang MD,&nbsp;Chang Cui MD,&nbsp;Cheng Cai MD,&nbsp;Weizhu Ju MD,&nbsp;Minglong Chen MD","doi":"10.1016/j.cjca.2025.06.077","DOIUrl":"10.1016/j.cjca.2025.06.077","url":null,"abstract":"<div><h3>Background</h3><div>Unipolar voltage mapping has shown value in delineating comprehensive atrial substrates. However, the clinical application of unipolar low-voltage areas (Uni-LVAs) in atrial fibrillation (AF) ablation is limited, largely because of the absence of a well established voltage threshold. In this study we aimed to: (1) define the threshold for Uni-LVA in the left atrium (LA); and (2) investigate the association between Uni-LVA burden and ablation outcomes in a prospective AF cohort.</div></div><div><h3>Methods</h3><div>The Uni-LVA threshold was defined as the average of the 6 cutoff values, representing the voltage at 95% of all electrograms from a reference cohort who underwent left-sided accessory pathway ablation and concomitant LA mapping. In a single-centre, prospective AF ablation cohort, LA mapping was conducted and the Uni-LVA burden was automatically calculated.</div></div><div><h3>Results</h3><div>Uni-LVA was defined as an area with an amplitude of &lt; 1.6 mV. In 145 patients, the Uni-LVA burden was automatically obtained using customized software. During a follow-up period of 16 ± 4 months, 44 patients experienced recurrence. Uni-LVA burden was significantly associated with recurrence rates. Compared with group 1 (&lt; 1%), the recurrence rates for group 2 (1%-10%) and group 3 (&gt; 10%) were significantly higher (hazard ratio, 5.08 [<em>P</em>&lt;0.001] and hazard ratio, 24.07 [<em>P</em> &lt; 0.001]). Receiver operator curve analysis showed significantly higher predictive efficiency for Uni-LVA burden (area under the curve, 0.880 vs 0.762; <em>P</em> &lt; 0.001) compared with the bipolar low voltage burden.</div></div><div><h3>Conclusions</h3><div>Using a unipolar voltage threshold of &lt; 1.6 mV, Uni-LVA burden was independently associated with long-term AF recurrence after ablation and outperformed bipolar assessment. This finding suggests Uni-LVA could serve as a valuable tool for prognostic evaluation.</div></div>","PeriodicalId":9555,"journal":{"name":"Canadian Journal of Cardiology","volume":"41 10","pages":"Pages 1991-2000"},"PeriodicalIF":5.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144667253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CJCA_ANN_Call for Original Papers - Gene-based Therapies","authors":"","doi":"10.1016/S0828-282X(25)01082-7","DOIUrl":"10.1016/S0828-282X(25)01082-7","url":null,"abstract":"","PeriodicalId":9555,"journal":{"name":"Canadian Journal of Cardiology","volume":"41 10","pages":"Pages A16-A17"},"PeriodicalIF":5.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145326592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Information for Readers","authors":"","doi":"10.1016/S0828-282X(25)01075-X","DOIUrl":"10.1016/S0828-282X(25)01075-X","url":null,"abstract":"","PeriodicalId":9555,"journal":{"name":"Canadian Journal of Cardiology","volume":"41 10","pages":"Page A13"},"PeriodicalIF":5.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145326897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}