{"title":"Benefit of Systematic “Jailed Wire” Technique for Bifurcation Provisional Stenting. A CABRIOLET Substudy","authors":"François Dérimay MD, PhD , Aurélien Mercier MD , Adel Aminian MD , Luc Maillard MD, PhD , Géraud Souteyrand MD, PhD , Pascal Motreff MD, PhD , Benoit Lattuca MD, PhD , Guillaume Cayla MD, PhD , Gilles Rioufol MD, PhD , Gérard Finet MD, PhD","doi":"10.1016/j.cjca.2024.12.021","DOIUrl":"10.1016/j.cjca.2024.12.021","url":null,"abstract":"<div><h3>Background</h3><div>Jailed wire (JW) in the side branch (SB) is recommended during coronary bifurcation provisional stenting, but there is uncertainty about the real benefit. Our objective was to evaluate the benefit of a JW technique in the <strong>C</strong>oronary <strong>A</strong>rtery <strong>B</strong>ifurcation <strong>R</strong>evascularization Without k<strong>I</strong>ssing ball<strong>O</strong>on inf<strong>L</strong>ation by r<strong>E</strong>po<strong>T</strong> (CABRIOLET) registry.</div></div><div><h3>Methods</h3><div>In CABRIOLET, which included 500 patients, we compared the primary composite end point of a poor final SB angiographic result (of <strong>T</strong>hrombolysis <strong>i</strong>n <strong>M</strong>yocardial <strong>I</strong>nfarction (TIMI) flow < III, dissection grade > B, thrombosis, residual stenosis > 70%, or additional SB stenting) whether JW was performed or not. On the basis of the usual operator practice, we also compared a systematic JW strategy: operators known to place JW frequently (> 75% performed), to a conditional strategy: selective JW practices (< 20% of JW).</div></div><div><h3>Results</h3><div>JW was performed in 251 patients (50.2%), without significant baseline clinical and angiographic differences compared with those who received no JW. JW was associated with higher primary end point (15.1% vs 8.4%; <em>P</em> < 0.05), and increased fluoroscopy time and contrast volume (15.9 ± 7.3 minutes and 181 ± 62 mL vs 13.3 ± 6.5 minutes and 161 ± 74 mL; <em>P</em> < 0.05). JW was performed in 12.1% of patients (26 of 214) in the conditional JW group and 78.7% (225 of 286) in systematic group. The primary end point was similar in both strategies (11.2% and 12.2%; <em>P</em> = 0.78), although with greater fluoroscopy time and contrast volume for systematic JW (180 ± 57 mL and 15.3 ± 7.5 minutes vs 162 ± 79 mL and 13.7 ± 6.1 minutes; <em>P</em> < 0.05). There was no difference in 1-year major adverse cardiovascular events depending on whether JW was performed or not and between conditional or systematic strategies.</div></div><div><h3>Conclusions</h3><div>In a large registry, JW was associated with poorer final SB angiographic results than no JW. Final SB angiographic results were similar between conditional or systematic JW strategies.</div></div>","PeriodicalId":9555,"journal":{"name":"Canadian Journal of Cardiology","volume":"41 5","pages":"Pages 871-877"},"PeriodicalIF":5.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142871524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chandu Sadasivan MD , Michael A. Seidman MD, PhD , Gavin Y. Oudit MD, PhD
{"title":"Editorial Commentary to Uncovering Early Irreversible Cardiac Damage in Patients With Fabry Disease: Getting to the Heart of It","authors":"Chandu Sadasivan MD , Michael A. Seidman MD, PhD , Gavin Y. Oudit MD, PhD","doi":"10.1016/j.cjca.2025.01.023","DOIUrl":"10.1016/j.cjca.2025.01.023","url":null,"abstract":"","PeriodicalId":9555,"journal":{"name":"Canadian Journal of Cardiology","volume":"41 5","pages":"Pages 952-955"},"PeriodicalIF":5.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143476428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Information for Readers","authors":"","doi":"10.1016/S0828-282X(25)00249-1","DOIUrl":"10.1016/S0828-282X(25)00249-1","url":null,"abstract":"","PeriodicalId":9555,"journal":{"name":"Canadian Journal of Cardiology","volume":"41 5","pages":"Page A10"},"PeriodicalIF":5.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143912594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"CJCA_ANN_Call for Original Papers_Endo","authors":"","doi":"10.1016/S0828-282X(25)00297-1","DOIUrl":"10.1016/S0828-282X(25)00297-1","url":null,"abstract":"","PeriodicalId":9555,"journal":{"name":"Canadian Journal of Cardiology","volume":"41 5","pages":"Pages A13-A14"},"PeriodicalIF":5.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143912596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jorge Nuche MD, PhD , Jules Mesnier MD , Julien Ternacle MD, PhD , Effat Rezaei PhD , Francisco Campelo-Parada MD, PhD , Marina Urena MD, PhD , Gabriela Veiga-Fernandez MD, PhD , Luis Nombela-Franco MD, PhD , Anna Franzone MD, PhD , Antonio J. Munoz-Garcia MD , Victoria Vilalta MD, PhD , Ander Regueiro MD, PhD , David del Val MD, PhD , Lluis Asmarats MD, PhD , Maria del Trigo MD, PhD , Vicenç Serra MD, PhD , Guillaume Bonnet MD, PhD , Melchior Jonveaux MD , Ronan Canitrot MD , Dominique Himbert MD , Asim N. Cheema MD
{"title":"Transcatheter Aortic Valve Replacement in Aortic Stenosis Patients With New York Heart Association Functional Class III or IV","authors":"Jorge Nuche MD, PhD , Jules Mesnier MD , Julien Ternacle MD, PhD , Effat Rezaei PhD , Francisco Campelo-Parada MD, PhD , Marina Urena MD, PhD , Gabriela Veiga-Fernandez MD, PhD , Luis Nombela-Franco MD, PhD , Anna Franzone MD, PhD , Antonio J. Munoz-Garcia MD , Victoria Vilalta MD, PhD , Ander Regueiro MD, PhD , David del Val MD, PhD , Lluis Asmarats MD, PhD , Maria del Trigo MD, PhD , Vicenç Serra MD, PhD , Guillaume Bonnet MD, PhD , Melchior Jonveaux MD , Ronan Canitrot MD , Dominique Himbert MD , Asim N. Cheema MD","doi":"10.1016/j.cjca.2024.12.025","DOIUrl":"10.1016/j.cjca.2024.12.025","url":null,"abstract":"<div><h3>Background</h3><div>Patients with symptomatic aortic stenosis are a vulnerable population with associated cardiac damage and a significant comorbidity burden. In this study we aimed to determine the rate, factors associated with, and prognostic value of poor functional status (New York Heart Association [NYHA] class III-IV) in patients with severe aortic stenosis undergoing transcatheter aortic valve replacement (TAVR).</div></div><div><h3>Methods</h3><div>This multicenter study included 6363 transarterial TAVR patients, classified according to baseline functional status (NYHA class I or II vs III or IV).</div></div><div><h3>Results</h3><div>A total of 3800 (60%) patients presented with NYHA class III or IV before the TAVR procedure. Atrial fibrillation (odds ratio [OR], 1.32; 95% confidence interval [CI], 1.11-1.58; <em>P</em> = 0.002), chronic kidney disease (CKD; OR, 1.73; 95% CI, 1.45-2.05; <em>P</em> < 0.001), chronic obstructive pulmonary disease (COPD; OR, 1.65; 95% CI, 1.32-2.05; <em>P</em> < 0.001), reduced left ventricular ejection fraction (OR, 2.28; 95% CI, 1.70-3.05; <em>P</em> < 0.001), and moderate and severe pulmonary hypertension were associated with a poor functional status. At 1-year follow-up, patients with NYHA class III or IV had higher rates of mortality (8.81 per 100 person-years [95% CI, 7.57-10.15] vs 13.12 per 100 person-years [95% CI, 11.80-14.58]; log rank, <em>P</em> < 0.001) and heart failure hospitalization (8.25 per 100 person-years [95% CI, 7.05-9.65] vs 12.5 per 100 person-years [95% CI, 11.24-14.00]; log rank, <em>P</em> = 0.005). Comorbidity factors (COPD, CKD) and signs of cardiac damage (atrial fibrillation, pulmonary hypertension) determined an increased risk of poorer clinical outcomes (<em>P</em> < 0.01 for all).</div></div><div><h3>Conclusions</h3><div>More than half of the patients undergoing TAVR in the contemporary era have presented with advanced functional class before the procedure, and this was associated with a greater comorbidity and cardiac damage burden. Patients with poorer baseline functional status exhibited worse clinical outcomes at 1-year follow-up. These findings highlight the need for further study on earlier interventions for patients with aortic stenosis.</div></div>","PeriodicalId":9555,"journal":{"name":"Canadian Journal of Cardiology","volume":"41 5","pages":"Pages 850-859"},"PeriodicalIF":5.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142876195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Smartphones and the Smart Heart: Balancing the Risks and Benefits of Mobile Devices in Disease Prevention","authors":"Alina Yang","doi":"10.1016/j.cjca.2025.01.021","DOIUrl":"10.1016/j.cjca.2025.01.021","url":null,"abstract":"","PeriodicalId":9555,"journal":{"name":"Canadian Journal of Cardiology","volume":"41 5","pages":"Page 956"},"PeriodicalIF":5.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143051597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Link Between Mobile Phone Use and Cardiovascular Disease: A Call for Greater Attention","authors":"Yanjun Zhang MD, Xianhui Qin MD","doi":"10.1016/j.cjca.2025.02.024","DOIUrl":"10.1016/j.cjca.2025.02.024","url":null,"abstract":"","PeriodicalId":9555,"journal":{"name":"Canadian Journal of Cardiology","volume":"41 5","pages":"Page 958"},"PeriodicalIF":5.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143476426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}