Vincent Dinh, Kenza Rahmouni, Tristan Koran, Vincent Chan
{"title":"Minimally Invasive Mitral Valve Repair in a Patient with Cerebral Palsy and Reduced Mobility: A Case Report.","authors":"Vincent Dinh, Kenza Rahmouni, Tristan Koran, Vincent Chan","doi":"10.1016/j.cjca.2025.03.016","DOIUrl":"https://doi.org/10.1016/j.cjca.2025.03.016","url":null,"abstract":"<p><p>Surgical repair remains the gold-standard therapy for degenerative mitral regurgitation (MR) and may be performed via a minimally invasive or sternotomy approach. Although well described, minimally invasive mitral valve repair (MVr) is performed in only a subset of patients with degenerative MR, with a recent prospective randomized study showing no difference in functional outcomes at 12 months compared with sternotomy. However, minimally invasive MVr can be performed safely and may offer superior outcomes compared to repair via sternotomy in selected patients. We present a patient with degenerative MR and cerebral palsy, for whom minimally invasive MVr was an ideal therapy.</p>","PeriodicalId":9555,"journal":{"name":"Canadian Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":5.8,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143699618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brandon Hathorn, Mark J Haykowsky, Jaime Almandoz, Ambarish Pandey, Satyam Sarma, Christopher M Hearon, Tony G Babb, Bryce N Balmain, Qi Fu, Vlad G Zaha, Benjamin D Levine, Michael D Nelson
{"title":"Insights into the role of obesity in Heart Failure with Preserved Ejection Fraction pathophysiology and management.","authors":"Brandon Hathorn, Mark J Haykowsky, Jaime Almandoz, Ambarish Pandey, Satyam Sarma, Christopher M Hearon, Tony G Babb, Bryce N Balmain, Qi Fu, Vlad G Zaha, Benjamin D Levine, Michael D Nelson","doi":"10.1016/j.cjca.2025.03.015","DOIUrl":"https://doi.org/10.1016/j.cjca.2025.03.015","url":null,"abstract":"<p><p>Heart failure (HF) is a significant global health issue, categorized by left ventricular ejection fraction, being either reduced (HFrEF: <0.40) or preserved (HFpEF: >0.50), or in the middle of this range. While the overall incidence of HF remains stable, HFpEF cases are increasing, representing about 50% of all HF cases. Outcomes for HFpEF are similar to HFrEF, leading to substantial healthcare resource utilization. Despite extensive research over the past two decades, the prognosis and mortality rates for HFpEF remain high. A key feature of HFpEF is exercise intolerance, characterized by severe exertional dyspnea and fatigue, which significantly impacts quality of life. The underlying mechanisms of exercise intolerance are not fully understood due to the complex pathophysiology and multi-system involvement. Obesity is a common comorbidity in HFpEF, especially in North America, leading to worsening symptoms, hemodynamics, and mortality rates. Increased adiposity leads to inflammation, hypertension, dyslipidemia, and insulin resistance, and impairing cardiac, vascular, pulmonary, and skeletal muscle function. Therefore, managing obesity is crucial in treating HFpEF. This review explores the pathophysiologic mechanisms of HFpEF, emphasizing obesity's role, and discusses current management strategies while identifying areas needing further research.</p>","PeriodicalId":9555,"journal":{"name":"Canadian Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":5.8,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143691129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammed Abbas, Alex Chitan, Matthew Cheung, Steve Kim, Ronald Carere, Thomas Roston, Darwin Yeung, Zachary Laksman, Kevin Ong
{"title":"Efficacy of Mavacamten Therapy Following Unsuccessful Septal Reduction in Obstructive Hypertrophic Cardiomyopathy: A Retrospective Analysis.","authors":"Mohammed Abbas, Alex Chitan, Matthew Cheung, Steve Kim, Ronald Carere, Thomas Roston, Darwin Yeung, Zachary Laksman, Kevin Ong","doi":"10.1016/j.cjca.2025.03.014","DOIUrl":"https://doi.org/10.1016/j.cjca.2025.03.014","url":null,"abstract":"","PeriodicalId":9555,"journal":{"name":"Canadian Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":5.8,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143691039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Medical Management for Patients 90 Years Old and Up After Acute Coronary Syndrome - Never Too Old.","authors":"Karen B Ho, Michelle M Graham","doi":"10.1016/j.cjca.2025.03.013","DOIUrl":"https://doi.org/10.1016/j.cjca.2025.03.013","url":null,"abstract":"","PeriodicalId":9555,"journal":{"name":"Canadian Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":5.8,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143691161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bryn E Falahee, John W Ostrominski, Alexander J Blood
{"title":"Digital Approaches to Obesity: Future Directions.","authors":"Bryn E Falahee, John W Ostrominski, Alexander J Blood","doi":"10.1016/j.cjca.2025.03.011","DOIUrl":"https://doi.org/10.1016/j.cjca.2025.03.011","url":null,"abstract":"<p><p>Creative strategies are urgently needed to improve guideline directed access to overweight and obesity care worldwide. Digital health innovations capable of safely expanding implementation of overweight and obesity treatments to a larger portion of the global population provide an important avenue to address the obesity epidemic. Digital health interventions should be integrated into existing healthcare systems and designed around the major needs of users (i.e. persons, providers, and healthcare systems). We explore how digital interventions may be tailored to enhance treatment for obesity, at both a personal and systems level, and make overweight and obesity treatments more accessible.</p>","PeriodicalId":9555,"journal":{"name":"Canadian Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":5.8,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143668822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reticulocyte Production Index in Heart Failure: Refining Prognosis Beyond Current Risk Markers?","authors":"Alejandro Godoy, Noel C Chan","doi":"10.1016/j.cjca.2025.03.010","DOIUrl":"10.1016/j.cjca.2025.03.010","url":null,"abstract":"","PeriodicalId":9555,"journal":{"name":"Canadian Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":5.8,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michael-Roy Raphael Durr, Ian G Burwash, Lawrence Lau, Hassan Alfraidi, Anahita Tavosi, Alwaleed Aljamaan, Graeme Prosperi-Porta, Maria Agustina Lopez Laporte, Roja Gauda, Luc Beauchesne, Vincent Chan, Michael Froeschl, Thierry Mesana, David Messika-Zeitoun
{"title":"Valvular Heart Disease: Be Prepared for the Next Epidemic.","authors":"Michael-Roy Raphael Durr, Ian G Burwash, Lawrence Lau, Hassan Alfraidi, Anahita Tavosi, Alwaleed Aljamaan, Graeme Prosperi-Porta, Maria Agustina Lopez Laporte, Roja Gauda, Luc Beauchesne, Vincent Chan, Michael Froeschl, Thierry Mesana, David Messika-Zeitoun","doi":"10.1016/j.cjca.2025.03.008","DOIUrl":"10.1016/j.cjca.2025.03.008","url":null,"abstract":"","PeriodicalId":9555,"journal":{"name":"Canadian Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":5.8,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nadhem Abdallah, Marcel Rivard, Robert Shapiro, Mengistu Simegn, Andrew Shaffer, Gautam R Shroff
{"title":"Persistent Hypoxemia Following Redo Tricuspid Valve Surgery: A Vicious Cycle of Shunting.","authors":"Nadhem Abdallah, Marcel Rivard, Robert Shapiro, Mengistu Simegn, Andrew Shaffer, Gautam R Shroff","doi":"10.1016/j.cjca.2025.03.009","DOIUrl":"10.1016/j.cjca.2025.03.009","url":null,"abstract":"","PeriodicalId":9555,"journal":{"name":"Canadian Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":5.8,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Obesity and Public Health-Dare We Have Hope?","authors":"Yoni Freedhoff","doi":"10.1016/j.cjca.2025.02.037","DOIUrl":"10.1016/j.cjca.2025.02.037","url":null,"abstract":"","PeriodicalId":9555,"journal":{"name":"Canadian Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":5.8,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christopher B Fordyce, Filio Bilia, Warwick Butt, Ren Jie Robert Yao, Yoan Lamarche, Varinder K Randhawa, Sean van Diepen
{"title":"Overcoming Inertia in Cardiogenic Shock: Bridging Gaps and Advancing Care.","authors":"Christopher B Fordyce, Filio Bilia, Warwick Butt, Ren Jie Robert Yao, Yoan Lamarche, Varinder K Randhawa, Sean van Diepen","doi":"10.1016/j.cjca.2025.03.007","DOIUrl":"10.1016/j.cjca.2025.03.007","url":null,"abstract":"","PeriodicalId":9555,"journal":{"name":"Canadian Journal of Cardiology","volume":" ","pages":""},"PeriodicalIF":5.8,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}