Cardiology in Review最新文献_第4页

A Review of Cardiac Preoperative Screening Guidelines for Liver Transplantation.

IF 2 4区医学

Cardiology in Review Pub Date : 2025-02-24 DOI: 10.1097/CRD.0000000000000883

Jasmine Garg, Tanya Sharma, Atul D Bali, William H Frishman, Wilbert S Aronow

引用次数: 0

Alcoholic Cardiomyopathy in Patients With Advanced Alcoholic Liver Disease: Single-Center Experience and Review of Literature.

IF 2 4区医学

Cardiology in Review Pub Date : 2025-02-24 DOI: 10.1097/CRD.0000000000000880

Roshan Dhand, Kenji Okumura, Kevin Wolfe, Roxana Bodin, Seigo Nishida, William H Frishman, Abhay Dhand

{"title":"Alcoholic Cardiomyopathy in Patients With Advanced Alcoholic Liver Disease: Single-Center Experience and Review of Literature.","authors":"Roshan Dhand, Kenji Okumura, Kevin Wolfe, Roxana Bodin, Seigo Nishida, William H Frishman, Abhay Dhand","doi":"10.1097/CRD.0000000000000880","DOIUrl":"https://doi.org/10.1097/CRD.0000000000000880","url":null,"abstract":"The impact of excessive alcohol on human health is associated with a lifetime cumulative use of alcohol and is further affected by various factors such as age, gender, nutritional status, concurrent cigarette smoking or drug use, diabetes, obesity, other cardiovascular diseases, and socio-economic status. Alcohol cardiomyopathy (ACM) is a type of acquired dilated cardiomyopathy, which is associated with long-term heavy alcohol consumption with historical rates varying from 3.8% to 47 % among patients with heart failure. Data regarding the prevalence of concurrent ACM in patients with alcoholic liver disease is limited. Among 483 patients with advanced liver disease who underwent liver transplant evaluation at a single transplant center during 2016-2021, based on screening transthoracic echocardiogram and a clear definition, none (0%) of the patients had alcoholic cardiomyopathy (range ejection fraction: 55-80%), 7% had left ventricular dilation (mild dilation: 82%), and 12.4% had diastolic dysfunction. We also review data regarding known risk factors, natural progression, and treatment of ACM, and further explore the evidence regarding the concurrence of alcohol-associated disease in liver with other organs such as heart and pancreas. In persons with excessive alcohol consumption, abstinence from alcohol or moderating its use has been shown to help decrease the progression of heart failure, arrythmias, and hypertension as well as liver dysfunction. Focus on the identification of both genetic markers and modifiable risk factors associated with various organ injuries in conjunction with public health policies for the safe use of alcohol is needed to mitigate the risk of alcohol use disorder.","PeriodicalId":9549,"journal":{"name":"Cardiology in Review","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143482344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Wearable Devices for Hemodynamic Assessment in Cardiovascular Disease: A Short Literature Review.

IF 2 4区医学

Cardiology in Review Pub Date : 2025-02-21 DOI: 10.1097/CRD.0000000000000875

Jyotpal Singh, Chase J Ellingson, Maria Gagarinova, Rishi Thakkar, Neha Mehta, Kirrat Ahmad, Sabiha Sultana, Shivani Bhat, Payam Dehghani

{"title":"Wearable Devices for Hemodynamic Assessment in Cardiovascular Disease: A Short Literature Review.","authors":"Jyotpal Singh, Chase J Ellingson, Maria Gagarinova, Rishi Thakkar, Neha Mehta, Kirrat Ahmad, Sabiha Sultana, Shivani Bhat, Payam Dehghani","doi":"10.1097/CRD.0000000000000875","DOIUrl":"https://doi.org/10.1097/CRD.0000000000000875","url":null,"abstract":"Hemodynamic parameters are frequently used in patients with cardiovascular disease to assess cardiac function, monitor disease progression, propose interventions, and determine prognosis. However, they require extensive resources, including specialized equipment and trained personnel, to measure with accuracy and precision. Wearable devices such as wristwatches have been shown to assess heart function, such as heart rate and detection of irregular heart rhythms. These wearable devices have also evolved to measure hemodynamic variables in a noninvasive, dynamic, and rapid manner. However, there is limited research on the accuracy of these wearables for hemodynamic function. This review assesses wearable devices and their utility compared with a clinical reference standard for hemodynamic assessment and highlights the strengths and weaknesses of such devices. Limited studies have found that wearable devices can demonstrate strong correlations when assessing cardiac output, stroke volume, systolic blood pressure and timing intervals, and pre-ejection period. Reproducibility studies in similar clinical conditions are needed, and many of the wearable devices have not received FDA/Health Canada approval, restricting their clinical use. Our review summarizes the current research landscape of wearable devices and hemodynamic assessment and proposes a framework for future research applications.","PeriodicalId":9549,"journal":{"name":"Cardiology in Review","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Aortic Valve Replacement Versus Conservative Management in Patients With Asymptomatic Aortic Stenosis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

IF 2 4区医学

Cardiology in Review Pub Date : 2025-02-21 DOI: 10.1097/CRD.0000000000000879

Sufyan Shahid, Hritvik Jain, Maryam Shahzad, Debankur Dey, Ayesha Batool, Siddhant Passey, Rahul Patel, Roopeessh Vempati

{"title":"Aortic Valve Replacement Versus Conservative Management in Patients With Asymptomatic Aortic Stenosis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.","authors":"Sufyan Shahid, Hritvik Jain, Maryam Shahzad, Debankur Dey, Ayesha Batool, Siddhant Passey, Rahul Patel, Roopeessh Vempati","doi":"10.1097/CRD.0000000000000879","DOIUrl":"https://doi.org/10.1097/CRD.0000000000000879","url":null,"abstract":"Aortic valve replacement (AVR) is recommended for symptomatic severe aortic stenosis (AS) patients. However, evidence of its role in asymptomatic patients with severe AS remains controversial. Hence, a systematic review and meta-analysis of randomized controlled trials comparing AVR to conservative management in patients with asymptomatic severe AS was conducted. A systematic literature search was performed on electronic databases including MEDLINE (via PubMed), Embase, and Cochrane CENTRAL Library until November 2024. A random effects model was used to pool individual risk ratios (RRs) with their corresponding 95% confidence intervals (CIs) using Review Manager Version 5.4.1 to calculate pooled effect estimates. Three randomized controlled trials with 1203 patients (42% females) were included. On pooled analysis, AVR significantly reduced the risk of hospitalization for heart failure (RR = 0.11, CI: 0.02-0.56, P = 0.008) compared with conservative care. However, there were no significant differences between the 2 groups in all-cause mortality (RR = 0.63, CI: 0.36-1.11, P = 0.11), stroke (RR = 0.59, CI: 0.35-1.01, P = 0.05), myocardial infarction (RR = 0.43, CI: 0.06-2.92, P = 0.38), or thromboembolic events (RR = 0.54, CI: 0.13-2.29, P = 0.40). In asymptomatic patients with severe AS, AVR significantly reduces the risk of hospitalization due to heart failure, with comparable risks in terms of all-cause mortality, myocardial infarction, stroke, and thromboembolic events compared with conservative management.","PeriodicalId":9549,"journal":{"name":"Cardiology in Review","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy of Colchicine in Stroke Prevention in Patients With Cardiovascular Diseases: A Meta-Analysis of Randomized Controlled Trials.

IF 2 4区医学

Cardiology in Review Pub Date : 2025-02-20 DOI: 10.1097/CRD.0000000000000872

Hritvik Jain, Raheel Ahmed, Muhammad Daoud Tariq, Sebastian Fox, Mushood Ahmed, Ramez M Odat, Siddhant Passey, Jyoti Jain, Siddharth Shah, Ameer Haider Cheema, Anwar Chahal

{"title":"Efficacy of Colchicine in Stroke Prevention in Patients With Cardiovascular Diseases: A Meta-Analysis of Randomized Controlled Trials.","authors":"Hritvik Jain, Raheel Ahmed, Muhammad Daoud Tariq, Sebastian Fox, Mushood Ahmed, Ramez M Odat, Siddhant Passey, Jyoti Jain, Siddharth Shah, Ameer Haider Cheema, Anwar Chahal","doi":"10.1097/CRD.0000000000000872","DOIUrl":"https://doi.org/10.1097/CRD.0000000000000872","url":null,"abstract":"Cardiovascular disease (CVD) is the leading cause of mortality and morbidity worldwide. Low-dose colchicine is a novel and nonstandard management approach for patients with CVDs who are at an increased risk of adverse events. However, few studies have reported the risk of stroke with colchicine, with controversial results. This meta-analysis aimed to compare the efficacy of colchicine and placebo for stroke prevention in patients with CVD. Major electronic databases were screened for randomized controlled trials (RCTs) comparing colchicine and placebo in patients with CVDs from inception to June 2024. Pooled estimates were calculated as risk ratios (RRs) with 95% confidence intervals (CIs) using an inverse-variance random-effects model. Statistical significance was set at P < 0.05. A total of 15 RCTs encompassing 25,116 patients with CVDs were included (12,568: colchicine and 12,548: placebo). The pooled analysis demonstrated a significant reduction in stroke [RR, 0.80 (95% CI, 0.64-0.99); P = 0.04] with colchicine compared with placebo. The risk of all-cause mortality [RR, 1.00 (95% CI, 0.77-1.28)] was comparable between the 2 groups. On subgroup analysis, low-dose colchicine (0.5 mg/day) demonstrated a significantly lower risk of stroke compared with high-dose (>0.5 mg/day) colchicine, which failed to achieve statistical significance. Based on this meta-analysis, colchicine significantly reduced stroke in patients with CVDs compared with placebo. This effect was most significant with low-dose colchicine at 0.5 mg/day. However, no differences were observed in all-cause mortality. Further long-term RCTs are warranted to investigate stroke prevention using colchicine in this population.","PeriodicalId":9549,"journal":{"name":"Cardiology in Review","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143457013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sugar-Free but Not Risk-Free? Exploring Artificial Sweeteners and Cardiovascular Disease.

IF 2 4区医学

Cardiology in Review Pub Date : 2025-02-19 DOI: 10.1097/CRD.0000000000000873

Lillian Huang, Ellen Huhulea, Eseiwi Aifuwa, William H Frishman, Wilbert S Aronow

{"title":"Sugar-Free but Not Risk-Free? Exploring Artificial Sweeteners and Cardiovascular Disease.","authors":"Lillian Huang, Ellen Huhulea, Eseiwi Aifuwa, William H Frishman, Wilbert S Aronow","doi":"10.1097/CRD.0000000000000873","DOIUrl":"https://doi.org/10.1097/CRD.0000000000000873","url":null,"abstract":"The consumption of artificial sweeteners has significantly increased globally, particularly as a substitute for sugar for the management of conditions such as diabetes and obesity, which are significant risk factors for cardiovascular disease. Despite their widespread use, the health impacts of artificial sweeteners remain contentious. Research has suggested that certain sweeteners may contribute to systemic inflammation, endothelial dysfunction, and disruptions in gut microbiota, potentially altering glucose metabolism and exacerbating metabolic conditions such as diabetes and obesity. However, other studies highlight potential benefits, such as weight control and improved glucose tolerance. Still, the long-term safety of artificial sweeteners, particularly with chronic consumption, remains uncertain. This literature review explores the cardiovascular risks associated with various artificial sweeteners, focusing on the 6 US Food and Drug Administration-approved nonnutritive sweeteners, aspartame, sucralose, saccharin, acesulfame K, cyclamate, and neotame, as well as nutritive sweeteners such as polyols (erythritol, xylitol, sorbitol, and maltitol). Ongoing research, including in vitro, animal, and clinical studies, aims to clarify the long-term cardiovascular and metabolic implications of artificial sweeteners and assess the safety of their widespread use across diverse populations.","PeriodicalId":9549,"journal":{"name":"Cardiology in Review","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143448327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Taurine and Berberine: Nutritional Interventions Targeting Cellular Mechanisms of Aging and Longevity. 牛磺酸和小檗碱：针对衰老和长寿细胞机制的营养干预。

IF 2 4区医学

Cardiology in Review Pub Date : 2025-02-19 DOI: 10.1097/CRD.0000000000000885

Jatin Thukral, Pyush Moudgil, Darshilkumar Maheta, Siddharth Pravin Agrawal, Harbir Kaur, Nikhil Thukral, William H Frishman, Wilbert S Aronow

{"title":"Taurine and Berberine: Nutritional Interventions Targeting Cellular Mechanisms of Aging and Longevity.","authors":"Jatin Thukral, Pyush Moudgil, Darshilkumar Maheta, Siddharth Pravin Agrawal, Harbir Kaur, Nikhil Thukral, William H Frishman, Wilbert S Aronow","doi":"10.1097/CRD.0000000000000885","DOIUrl":"https://doi.org/10.1097/CRD.0000000000000885","url":null,"abstract":"Aging is a multifaceted biological process characterized by progressive physiological decline and increased susceptibility to diseases. Central to this process are molecular and cellular changes that contribute to hallmark features of aging, including mitochondrial dysfunction, genomic instability, telomere attrition, and cellular senescence. Emerging research highlights the role of nutrient deficiencies in accelerating aging, bringing dietary supplements such as taurine and berberine into focus. Taurine, a sulfur-containing amino acid, plays a critical role in cellular protection, osmoregulation, and antioxidant defense, with evidence linking its deficiency to cellular senescence, mitochondrial dysfunction, and stem cell exhaustion. Berberine, an isoquinoline alkaloid, exerts antiaging effects by modulating key signaling pathways, including adenosine monophosphate-activated protein kinase/mechanistic target of rapamycin and sirtuin 1, and promoting mitohormesis. This review explores the mechanisms by which taurine and berberine mitigate aging processes, highlighting their effects on cellular metabolism, stress response, and longevity. Animal studies demonstrate their potential to enhance health span and lifespan although human clinical trials remain limited. Future research should focus on elucidating their molecular pathways, evaluating their combined effects with other interventions such as caloric restriction, and optimizing dosage for clinical applications. Taurine and berberine represent promising therapeutic candidates for addressing fundamental aspects of aging and advancing strategies for healthy aging and lifespan extension.","PeriodicalId":9549,"journal":{"name":"Cardiology in Review","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143448329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cerebral Venous Sinus Thrombosis During Pregnancy and the Postpartum Period: A Review of Pathophysiological Mechanisms, Clinical Manifestations, and Treatment Approaches.

IF 2 4区医学

Cardiology in Review Pub Date : 2025-02-12 DOI: 10.1097/CRD.0000000000000853

Maya V Pandit, William H Frishman

{"title":"Cerebral Venous Sinus Thrombosis During Pregnancy and the Postpartum Period: A Review of Pathophysiological Mechanisms, Clinical Manifestations, and Treatment Approaches.","authors":"Maya V Pandit, William H Frishman","doi":"10.1097/CRD.0000000000000853","DOIUrl":"https://doi.org/10.1097/CRD.0000000000000853","url":null,"abstract":"Cerebral venous sinus thrombosis (CVST) is a rare neurological emergency associated with significant morbidity and mortality. CVST has been found to account for up to 57% of pregnancy-related strokes. Pregnancy and the postpartum period are associated with physiological changes that lead to a hypercoagulable state, increasing the risk for CVST. The pathophysiological mechanism for CVST involves increased venule and capillary pressure as well as intracranial pressure, which lead to clinical manifestations such as headaches, seizures, and focal neurological deficits. Diagnosis involves imaging including computed tomography, magnetic resonance imaging, venography, and in some cases, cerebral angiography. Treatment options during pregnancy and postpartum include anticoagulation with low molecular weight heparin and symptomatic management. Further research is needed to elucidate the safety and efficacy of endovascular treatment techniques in severe or refractory cases of CVST, particularly during pregnancy and puerperium. In this review, we describe the physiological changes of pregnancy, outline the pathophysiological mechanisms and clinical findings of CVST, and discuss treatment approaches specific to pregnancy and the postpartum period.","PeriodicalId":9549,"journal":{"name":"Cardiology in Review","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143390188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Literature Review: Effects of Environmental Noise on the Cardiovascular Health.

IF 2 4区医学

Cardiology in Review Pub Date : 2025-02-12 DOI: 10.1097/CRD.0000000000000852

Andrew Jun Wang, William Howard Frishman

{"title":"Literature Review: Effects of Environmental Noise on the Cardiovascular Health.","authors":"Andrew Jun Wang, William Howard Frishman","doi":"10.1097/CRD.0000000000000852","DOIUrl":"https://doi.org/10.1097/CRD.0000000000000852","url":null,"abstract":"The adverse effects of environmental noise on human health have been recognized for more than a century. In particular, during the last decades, the vast majority of studies have focused on the detrimental role of noise in the induction of cardiovascular diseases. In this study, we aim to conduct a literature review on chronic stress responses induced by environmental noise, the risk of cardiovascular disease, and the underlying pathophysiological mechanisms. We retrieved the publications from the PubMed database by searching for \"noise AND cardiovascular.\" By reviewing these publications in this study, we will first describe the epidemiologic research on cardiovascular risk factors and diseases induced by environmental noise, then discuss the mechanism(s) underlying these noise-induced cardiovascular impairments based on clinical and experimental studies, and finally evaluate the strategies to mitigate the effects of noise on cardiovascular health. We also evaluate the studies that describe the effects of noise level and noise intermittency, such as train noise, on cardiovascular health. We discuss whether environmental noise should be part of a risk factor profile for cardiovascular disease and how we should manage it, and assess the strategy that can be used to mitigate the noise-induced physiopathological changes. Furthermore, we briefly describe the effects of air pollution and heavy metals on cardiovascular health and discuss the relevance of these environmental stressors in the noise-induced cardiovascular disease. Our studies suggest that future studies are warranted to investigate new strategies that can mitigate the adverse effects of environmental noise on cardiovascular health.","PeriodicalId":9549,"journal":{"name":"Cardiology in Review","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143398215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chelation Therapy in Coronary Artery Disease: Fact or Fiction?

IF 2 4区医学

Cardiology in Review Pub Date : 2025-02-12 DOI: 10.1097/CRD.0000000000000871

Sara Hasan, Manish A Parikh, Dhaval B Trivedi, William H Frishman, Stephen J Peterson

引用次数: 0