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Correction: Hot off the Press 更正：热销
IF 11.9 1区 化学
Natural Product Reports Pub Date : 2024-01-01 DOI: 10.1039/d3np90056h
Robert A. Hill , Andrew Sutherland
{"title":"Correction: Hot off the Press","authors":"Robert A. Hill ,&nbsp;Andrew Sutherland","doi":"10.1039/d3np90056h","DOIUrl":"10.1039/d3np90056h","url":null,"abstract":"<div><p>Correction for ‘Hot off the Press’ by Robert A. Hill <em>et al.</em>, <em>Nat. Prod. Rep.</em>, 2023, <strong>40</strong>, 1816–1821, <span>https://doi.org/10.1039/d3np90052e</span>.</p></div>","PeriodicalId":94,"journal":{"name":"Natural Product Reports","volume":null,"pages":null},"PeriodicalIF":11.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139083531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction: Future antimalarials from Artemisia? A rationale for natural product mining against drug-refractory Plasmodium stages 更正：未来的青蒿抗疟药？针对难治性疟原虫阶段挖掘天然产品的理由。
IF 11.9 1区 化学
Natural Product Reports Pub Date : 2024-01-01 DOI: 10.1039/d4np90001d
Alexandre Maciuk , Dominique Mazier , Romain Duval
{"title":"Correction: Future antimalarials from Artemisia? A rationale for natural product mining against drug-refractory Plasmodium stages","authors":"Alexandre Maciuk ,&nbsp;Dominique Mazier ,&nbsp;Romain Duval","doi":"10.1039/d4np90001d","DOIUrl":"10.1039/d4np90001d","url":null,"abstract":"<div><p>Correction for ‘Future antimalarials from <em>Artemisia</em>? A rationale for natural product mining against drug-refractory <em>Plasmodium</em> stages’ by Alexandre Maciuk <em>et al.</em>, <em>Nat. Prod. Rep.</em>, 2023, <strong>40</strong>, 1130–1144, <span>https://doi.org/10.1039/D3NP00001J</span>.</p></div>","PeriodicalId":94,"journal":{"name":"Natural Product Reports","volume":null,"pages":null},"PeriodicalIF":11.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139477800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hot off the Press 刚出版的。
IF 11.9 1区 化学
Natural Product Reports Pub Date : 2023-12-04 DOI: 10.1039/D3NP90052E
Robert A. Hill and Andrew Sutherland
{"title":"Hot off the Press","authors":"Robert A. Hill and Andrew Sutherland","doi":"10.1039/D3NP90052E","DOIUrl":"10.1039/D3NP90052E","url":null,"abstract":"<p >A personal selection of 32 recent papers is presented covering various aspects of current developments in bioorganic chemistry and novel natural products such as alscholarine A from <em>Alstonia scholaris</em>.</p>","PeriodicalId":94,"journal":{"name":"Natural Product Reports","volume":null,"pages":null},"PeriodicalIF":11.9,"publicationDate":"2023-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138476272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Strategies and tactics for the synthesis of lipid I and II and shortened analogues: functional building blocks of bacterial cell wall biosynthesis 脂质I和II及其缩短类似物的合成策略和策略:细菌细胞壁生物合成的功能构建块。
IF 11.9 1区 化学
Natural Product Reports Pub Date : 2023-11-15 DOI: 10.1039/d3np00018d
Christina Braun , Lukas Martin Wingen , Dirk Menche
{"title":"Strategies and tactics for the synthesis of lipid I and II and shortened analogues: functional building blocks of bacterial cell wall biosynthesis","authors":"Christina Braun ,&nbsp;Lukas Martin Wingen ,&nbsp;Dirk Menche","doi":"10.1039/d3np00018d","DOIUrl":"10.1039/d3np00018d","url":null,"abstract":"<div><p>Covering: the literature up to 2022</p><p>This study discusses various synthetic strategies for the synthesis of lipid II, the pivotal bacterial cell wall precursor. In detail, it examines different solution phase approaches, reviews various solid phase sequences, and evaluates enzymatic ventures. The underlying rationale, scope, limitations, and perspectives of these strategies are discussed. The focus is on the tactics and strategies towards the authentic peptidoglycan compound, as well as analogues thereof with shortened side chains, which are increasingly recognized as more beneficial surrogates with more favorable physicochemical properties.</p></div>","PeriodicalId":94,"journal":{"name":"Natural Product Reports","volume":null,"pages":null},"PeriodicalIF":11.9,"publicationDate":"2023-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9871351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Machine learning-assisted structure annotation of natural products based on MS and NMR data 基于MS和NMR数据的机器学习辅助天然产物结构标注。
IF 11.9 1区 化学
Natural Product Reports Pub Date : 2023-11-15 DOI: 10.1039/d3np00025g
Guilin Hu , Minghua Qiu
{"title":"Machine learning-assisted structure annotation of natural products based on MS and NMR data","authors":"Guilin Hu ,&nbsp;Minghua Qiu","doi":"10.1039/d3np00025g","DOIUrl":"10.1039/d3np00025g","url":null,"abstract":"<div><p>Covering: up to March 2023</p><p>Machine learning (ML) has emerged as a popular tool for analyzing the structures of natural products (NPs). This review presents a summary of the recent advancements in ML-assisted mass spectrometry (MS) and nuclear magnetic resonance (NMR) data analysis to establish the chemical structures of NPs. First, ML-based MS/MS analyses that rely on library matching are discussed, which involves the utilization of ML algorithms to calculate similarity, predict the MS/MS fragments, and form molecular fingerprint. Then, ML assisted MS/MS structural annotation without library matching is reviewed. Furthermore, the cases of ML algorithms in assisting structural studies of NPs based on NMR are discussed from four perspectives: NMR prediction, functional group identification, structural categorization and quantum chemical calculation. Finally, the review concludes with a discussion of the challenges and the trends associated with the structural establishment of NPs based on ML algorithms.</p></div>","PeriodicalId":94,"journal":{"name":"Natural Product Reports","volume":null,"pages":null},"PeriodicalIF":11.9,"publicationDate":"2023-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9898277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Highlights of biosynthetic enzymes and natural products from symbiotic cyanobacteria† 来自共生蓝藻的生物合成酶和天然产物的亮点。
IF 11.9 1区 化学
Natural Product Reports Pub Date : 2023-11-15 DOI: 10.1039/d3np00011g
Paul M. D'Agostino
{"title":"Highlights of biosynthetic enzymes and natural products from symbiotic cyanobacteria†","authors":"Paul M. D'Agostino","doi":"10.1039/d3np00011g","DOIUrl":"10.1039/d3np00011g","url":null,"abstract":"<div><p>Covering: up to 2023</p><p>Cyanobacteria have long been known for their intriguing repertoire of natural product scaffolds, which are often distinct from other phyla. Cyanobacteria are ecologically significant organisms that form a myriad of different symbioses including with sponges and ascidians in the marine environment or with plants and fungi, in the form of lichens, in terrestrial environments. Whilst there have been several high-profile discoveries of symbiotic cyanobacterial natural products, genomic data is scarce and discovery efforts have remained limited. However, the rise of (meta-)genomic sequencing has improved these efforts, emphasized by a steep increase in publications in recent years. This highlight focuses on selected examples of symbiotic cyanobacterial-derived natural products and their biosyntheses to link chemistry with corresponding biosynthetic logic. Further highlighted are remaining gaps in knowledge for the formation of characteristic structural motifs. It is anticipated that the continued rise of (meta-)genomic next-generation sequencing of symbiontic cyanobacterial systems will lead to many exciting discoveries in the future.</p></div>","PeriodicalId":94,"journal":{"name":"Natural Product Reports","volume":null,"pages":null},"PeriodicalIF":11.9,"publicationDate":"2023-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9775012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Industrial total synthesis of natural medicines 天然药物的工业全合成。
IF 11.9 1区 化学
Natural Product Reports Pub Date : 2023-11-15 DOI: 10.1039/d3np00020f
Xiao-Yu Liu , Yong Qin
{"title":"Industrial total synthesis of natural medicines","authors":"Xiao-Yu Liu ,&nbsp;Yong Qin","doi":"10.1039/d3np00020f","DOIUrl":"10.1039/d3np00020f","url":null,"abstract":"<div><p>Total synthesis offers a key approach to the production of natural medicines if sufficient quantities cannot be obtained due to low natural abundance or lack of efficient fermentation or semi-synthesis methods. This Viewpoint outlines the previous and current states of research as they apply to the total synthesis of natural medicines on an industrial scale and provides a holistic view on the potential for future developments in the field.</p></div>","PeriodicalId":94,"journal":{"name":"Natural Product Reports","volume":null,"pages":null},"PeriodicalIF":11.9,"publicationDate":"2023-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9960685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Natural products as anthelmintics: safeguarding animal health 天然驱虫产品:保障动物健康。
IF 11.9 1区 化学
Natural Product Reports Pub Date : 2023-11-15 DOI: 10.1039/d3np00019b
Angela A. Salim , Mark S. Butler , Mark A. T. Blaskovich , Ian R. Henderson , Robert J. Capon
{"title":"Natural products as anthelmintics: safeguarding animal health","authors":"Angela A. Salim ,&nbsp;Mark S. Butler ,&nbsp;Mark A. T. Blaskovich ,&nbsp;Ian R. Henderson ,&nbsp;Robert J. Capon","doi":"10.1039/d3np00019b","DOIUrl":"10.1039/d3np00019b","url":null,"abstract":"<div><p>Covering literature to December 2022</p><p>This review provides a comprehensive account of all natural products (500 compounds, including 17 semi-synthetic derivatives) described in the primary literature up to December 2022, reported to be capable of inhibiting the egg hatching, motility, larval development and/or the survival of helminths (<em>i.e.</em>, nematodes, flukes and tapeworms). These parasitic worms infect and compromise the health and welfare, productivity and lives of commercial livestock (<em>i.e.</em>, sheep, cattle, horses, pigs, poultry and fish), companion animals (<em>i.e.</em>, dogs and cats) and other high value, endangered and/or exotic animals. Attention is given to chemical structures, as well as source organisms and anthelmintic properties, including the nature of bioassay target species, <em>in vivo</em> animal hosts, and measures of potency.</p></div>","PeriodicalId":94,"journal":{"name":"Natural Product Reports","volume":null,"pages":null},"PeriodicalIF":11.9,"publicationDate":"2023-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9951543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hot off the Press 关掉媒体。
IF 11.9 1区 化学
Natural Product Reports Pub Date : 2023-10-04 DOI: 10.1039/D3NP90045B
Robert A. Hill and Andrew Sutherland
{"title":"Hot off the Press","authors":"Robert A. Hill and Andrew Sutherland","doi":"10.1039/D3NP90045B","DOIUrl":"10.1039/D3NP90045B","url":null,"abstract":"<p >A personal selection of 32 recent papers is presented covering various aspects of current developments in bioorganic chemistry and novel natural products, such as dysambiol from a <em>Dysidea</em> species.</p>","PeriodicalId":94,"journal":{"name":"Natural Product Reports","volume":null,"pages":null},"PeriodicalIF":11.9,"publicationDate":"2023-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41098975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chemistry, biosynthesis and biology of floral volatiles: roles in pollination and other functions 花挥发物的化学、生物合成和生物学：在授粉和其他功能中的作用
IF 11.9 1区 化学
Natural Product Reports Pub Date : 2023-09-04 DOI: 10.1039/D3NP00024A
Stefan Dötterl and Jonathan Gershenzon
{"title":"Chemistry, biosynthesis and biology of floral volatiles: roles in pollination and other functions","authors":"Stefan Dötterl and Jonathan Gershenzon","doi":"10.1039/D3NP00024A","DOIUrl":"10.1039/D3NP00024A","url":null,"abstract":"<p>Covering: 2010 to 2023</p><p>Floral volatiles are a chemically diverse group of plant metabolites that serve multiple functions. Their composition is shaped by environmental, ecological and evolutionary factors. This review will summarize recent advances in floral scent research from chemical, molecular and ecological perspectives. It will focus on the major chemical classes of floral volatiles, on notable new structures, and on recent discoveries regarding the biosynthesis and the regulation of volatile emission. Special attention will be devoted to the various functions of floral volatiles, not only as attractants for different types of pollinators, but also as defenses of flowers against enemies. We will also summarize recent findings on how floral volatiles are affected by abiotic stressors, such as increased temperatures and drought, and by other organisms, such as herbivores and flower-dwelling microbes. Finally, this review will indicate current research gaps, such as the very limited knowledge of the isomeric pattern of chiral compounds and its importance in interspecific interactions.</p>","PeriodicalId":94,"journal":{"name":"Natural Product Reports","volume":null,"pages":null},"PeriodicalIF":11.9,"publicationDate":"2023-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2023/np/d3np00024a?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10500272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
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