Cardiology journal最新文献

{"title":"Study design and rationale for comparison of the incidence of slow flow following rotational atherectomy to severely calcified coronary artery lesions between short single session and long single session: The randomized ROTASOLO trial.","authors":"Kenichi Sakakura, Hiroyuki Jinnouchi, Yousuke Taniguchi, Takunori Tsukui, Yusuke Watanabe, Kei Yamamoto, Masaru Seguchi, Hiroshi Wada, Yoshimasa Tsurumaki, Takaaki Mase, Yusuke Tamanaha, Kenshiro Arao, Norifumi Kubo, Hideo Fujita","doi":"10.5603/CJ.a2023.0030","DOIUrl":"https://doi.org/10.5603/CJ.a2023.0030","url":null,"abstract":"This article is available in open access under Creative Common Attribution-Non-Commercial-No Derivatives 4.0 International (CC BY-NC-ND 4.0) license, allowing to download articles and share them with others as long as they credit the authors and the publisher, but without permission to change them in any way or use them commercially. Cardiology Journal 2023, Vol. 30, No. 3, 483–488 DOI: 10.5603/CJ.a2023.0030 Copyright © 2023 Via Medica ISSN 1897–5593 eISSN 1898–018X STUDY PROTOCOL INTERVENTIONAL CARDIOLOGY","PeriodicalId":9492,"journal":{"name":"Cardiology journal","volume":"30 3","pages":"483-488"},"PeriodicalIF":2.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/39/2f/cardj-30-3-483.PMC10287080.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9760683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Colchicine - From rheumatology to the new kid on the block: Coronary syndromes and COVID-19.","authors":"Stanisław Surma, Marcin Basiak, Monika Romańczyk, Krzysztof J Filipiak, Bogusław Okopień","doi":"10.5603/CJ.a2021.0123","DOIUrl":"10.5603/CJ.a2021.0123","url":null,"abstract":"<p><p>Colchicine is an effective anti-inflammatory agent used to treat gout, coronary artery disease, viral pericarditis, and familial Mediterranean fever. It has been found to act by preventing the polymerization of the protein called tubulin, thus inhibiting inflammasome activation, proinflammatory chemokines, and cellular adhesion molecules. Accumulating evidence suggests that some patients with coronavirus disease 2019 (COVID-19) suffer from \"cytokine storm\" syndrome. The ideal anti-inflammatory in this setting would be one that is readily available, cheap, orally administered, with a good safety profile, well- tolerated, and that prevents or modulates inflammasome activation. The researchers selected colchicine for their study. This paper is a review of the literature describing the effects of colchicine, which is a drug that is being increasingly used, especially when standard therapy fails. Colchicine was shown to reduce inflammatory lung injury and respiratory failure by interfering with leukocyte activation and recruitment. In this publication, we try to systematically review the current data on new therapeutic options for colchicine. The article focuses on new data from clinical trials in COVID-19, rheumatic, cardiovascular, and other treatment such as familial Mediterranean fever, chronic urticaria, and PFAPA syndrome (periodic fever, aphthous, stomatitis, pharyngitis, and cervical adenitis). We also summarize new reports on the side effects, drug interactions, and safety of colchicine.</p>","PeriodicalId":9492,"journal":{"name":"Cardiology journal","volume":"30 2","pages":"297-311"},"PeriodicalIF":2.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/15/5d/cardj-30-2-297.PMC10129269.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9770047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ST-segment elevation myocardial infarction as a COVID-19 manifestation in a recent heart transplant recipient.","authors":"Alicja Radtke-Łysek,&nbsp;Michał Bohdan,&nbsp;Maksymilian Mielczarek,&nbsp;Marek Koziński,&nbsp;Marcin Gruchała","doi":"10.5603/CJ.2023.0009","DOIUrl":"https://doi.org/10.5603/CJ.2023.0009","url":null,"abstract":"<p><p>< p > < /p >.</p>","PeriodicalId":9492,"journal":{"name":"Cardiology journal","volume":"30 1","pages":"155-156"},"PeriodicalIF":2.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ff/e6/cardj-30-1-155.PMC9987549.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9407504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of transcarotid versus transapical transcatheter aortic valve implantation outcomes in patients with severe aortic stenosis and contraindications for transfemoral access.","authors":"Damian Hudziak,&nbsp;Radosław Targoński,&nbsp;Wojciech Wańha,&nbsp;Radosław Gocoł,&nbsp;Adrianna Hajder,&nbsp;Radosław Parma,&nbsp;Tomasz Figatowski,&nbsp;Tomasz Darocha,&nbsp;Marek A Deja,&nbsp;Wojciech Wojakowski,&nbsp;Dariusz Jagielak","doi":"10.5603/CJ.a2021.0071","DOIUrl":"https://doi.org/10.5603/CJ.a2021.0071","url":null,"abstract":"<p><strong>Background: </strong>The purpose of this study was to compare the safety and clinical outcomes of transcarotid (TC) and transapical access (TA) transcatheter aortic valve implantation (TAVI) patients whom the transfemoral approach (TF) was not feasible.</p><p><strong>Methods: </strong>The analysis included consecutive patients with severe symptomatic aortic stenosis treated from 2017 to 2020 with TC-TAVI or TA-TAVI in two high-volume TAVI centers. The approach was selected by multidisciplinary heart teams after analyzing multislice computed tomography of the heart, aorta and peripheral arteries, transthoracic echocardiography and coronary angiography.</p><p><strong>Results: </strong>One hundred and two patients were treated with alternative TAVI accesses (TC; n = 49 and TA; n = 53) in our centers. The groups were similar regarding age, gender, New York Heart Association class, and echocardiography parameters. Patients treated with TC-TAVI had significantly higher surgical risk. The procedural success rate was similar in both groups (TC-TAVI 98%; TA-TAVI 98.1%; p = 0.95). The rate of Valve Academic Research Consortium-2 defined clinical events was low in both groups. The percentage of new-onset rhythm disturbances and permanent pacemaker implantation was similar in TC and TA TAVI (4.1% vs. 11.3%; p = 0.17 and 10.2% vs. 5.7%; p = 0.39, respectively). In the TA-TAVI group, significantly more cases of pneumonia and blood transfusions were observed (11% vs. 0%; p = 0.01 and 30.2% vs. 12.2%; p = 0.03). The 30-day mortality was similar in TC and TA groups (4.1% vs. 5.7%; p = 0.71, respectively).</p><p><strong>Conclusions: </strong>Both TC and TA TAVI are safe procedures in appropriately selected patients and are associated with a low risk of complications.</p>","PeriodicalId":9492,"journal":{"name":"Cardiology journal","volume":"30 2","pages":"188-195"},"PeriodicalIF":2.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/4f/93/cardj-30-2-188.PMC10129253.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9400955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of first wave of the SARS-CoV-2 2019 pandemic in Poland on characteristics and outcomes of patients hospitalized due to stable coronary artery disease.","authors":"Justyna Jankowska-Sanetra,&nbsp;Krzysztof Sanetra,&nbsp;Marta Konopko,&nbsp;Monika Kutowicz,&nbsp;Magdalena Synak,&nbsp;Krzysztof Milewski,&nbsp;Paweł Kaźmierczak,&nbsp;Łukasz Kołtowski,&nbsp;Piotr P Buszman","doi":"10.5603/CJ.a2022.0094","DOIUrl":"https://doi.org/10.5603/CJ.a2022.0094","url":null,"abstract":"<p><strong>Background: </strong>An investigation of baseline characteristics, treatment, and outcomes in patients with stable coronary disease after the first wave of the severe acute respiratory syndrome coronavirus 2 (SARS- -CoV-2) pandemic may provide valuable data and is beneficial for public health strategy in upcoming years.</p><p><strong>Methods: </strong>A multi-institutional registry, including 10 cardiology departments, was searched for patients admitted from June 2020 to October 2020. The baseline characteristics (age, gender, symptoms, comorbidities), treatment (non-invasive, invasive, surgical), and hospitalization outcome (mortality, myocardial infarction, stroke, composite endpoint - major adverse cardiac and cerebrovascular events [MACCE]) were evaluated. The comparison was made to parameters presented by patients from the same timeframe in 2019 (June-October). Multivariable analysis was performed.</p><p><strong>Results: </strong>Number of hospitalized stable patients following lockdown was lower (2498 vs. 1903; p < 0.0001). They were younger (68.0 vs. 69.0; p < 0.019), more likely to present with hypertension (88.5% vs. 77.5%; p < 0.0001), diabetes (35.7% vs. 31.5%; p = 0.003), hyperlipidemia (67.9% vs. 55.4%; p < 0.0001), obesity (35.8% vs. 31.3%; p = 0.002), and more pronounced symptoms (Canadian Cardiovascular Society [CCS] III and CCS class IV angina: 30.4% vs. 26.5%; p = 0.005). They underwent percutaneous treatment more often (35.0% vs. 25.9%; p < 0.0001) and were less likely to be referred for surgery (3.7% vs. 4.9%; p = 0.0001). There were no significant differences in hospitalization outcome. New York Heart Association (NYHA) class IV for heart failure was a risk factor for both mortality and MACCE in multivariate analysis.</p><p><strong>Conclusions: </strong>The SARS-CoV-2 2019 pandemic affected the characteristics and hospitalization course of stable angina patients hospitalized following the first wave. The hospitalization outcome was similar in the analyzed time intervals. The higher prevalence of comorbidities raises concern regarding upcoming years.</p>","PeriodicalId":9492,"journal":{"name":"Cardiology journal","volume":"30 3","pages":"337-343"},"PeriodicalIF":2.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/61/ed/cardj-30-3-337.PMC10287081.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10079432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ulnar artery thrombosis after percutaneous thrombin injection of a pseudoaneurysm with a concomitant radial artery occlusion: Three complications after percutaneous coronary intervention.","authors":"Angela Di Giorgio,&nbsp;Claudia Carnuccio,&nbsp;Antonio Nesci,&nbsp;Alessia D'Alessandro,&nbsp;Angelo Santoliquido","doi":"10.5603/cj.94372","DOIUrl":"10.5603/cj.94372","url":null,"abstract":"A 78-year-old woman was admitted to our hospital for ongoing chest pain. Electrocardiogram showed ST-segment elevation in inferior leads and primary percutaneous coronary intervention (PCI) was successfully performed from the right ulnar artery, as a result of cannulation failure of the ipsilateral radial artery. The patient reported a right transradial PCI some years earlier. After removal of the hemostatic device, a painful pulsatile mass was revealed in the distal forearm. Color Doppler ultrasonography (CDUS) showed complete occlusion of the right radial artery and iatrogenic ulnar artery pseudoaneurysm (Fig. 1)","PeriodicalId":9492,"journal":{"name":"Cardiology journal","volume":"30 4","pages":"675-676"},"PeriodicalIF":2.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d9/57/cardj-30-4-675.PMC10508067.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10212354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sodium restriction in patients with chronic heart failure and reduced ejection fraction: A randomized controlled trial.","authors":"Juan Betuel Ivey-Miranda,&nbsp;Eduardo Almeida-Gutierrez,&nbsp;Raul Herrera-Saucedo,&nbsp;Edith Liliana Posada-Martinez,&nbsp;Adolfo Chavez-Mendoza,&nbsp;Genaro Hiram Mendoza-Zavala,&nbsp;Jose Angel Cigarroa-Lopez,&nbsp;Jose Antonio Magaña-Serrano,&nbsp;Roxana Rivera-Leaños,&nbsp;Alberto Treviño-Mejia,&nbsp;Cristina Revilla-Matute,&nbsp;Eduardo Josue Flores-Umanzor,&nbsp;Nilda Espinola-Zavaleta,&nbsp;Arturo Orea-Tejeda,&nbsp;Juan Garduño-Espinosa,&nbsp;Guillermo Saturno-Chiu,&nbsp;Veena S Rao,&nbsp;Jeffrey Moore Testani,&nbsp;Gabriela Borrayo-Sanchez","doi":"10.5603/CJ.a2021.0098","DOIUrl":"10.5603/CJ.a2021.0098","url":null,"abstract":"<p><strong>Background: </strong>Sodium restriction is recommended for patients with heart failure (HF) despite the lack of solid clinical evidence from randomized controlled trials. Whether or not sodium restrictions provide beneficial cardiac effects is not known.</p><p><strong>Methods: </strong>The present study is a randomized, double-blind, controlled trial of stable HF patients with ejection fraction ≤ 40%. Patients were allocated to sodium restriction (2 g of sodium/day) vs. control (3 g of sodium/day). The primary outcome was change in N-terminal pro-B-type natriuretic peptide (NT-proBNP) at 20 weeks. Secondary outcomes included quality of life and adverse safety events (HF readmission, blood pressure or electrolyte abnormalities).</p><p><strong>Results: </strong>Seventy patients were enrolled. Median baseline sodium consumption was 3268 (2225-4537) mg/day. Adherence to the intervention based on 24-hour urinary sodium was 32%. NT-proBNP and quality of life did not significantly change between groups (p > 0.05 for both). Adverse safety events were not significantly different between the arms (p > 0.6 for all). In the per protocol analysis, patients who achieved a sodium intake < 2500 mg/day at the intervention conclusion showed improvements in NT-proBNP levels (between-group difference: -55%, 95% confidence interval -27 to -73%; p = 0.002) and quality of life (between-group difference: -11 ± 5 points; p = 0.04). Blood pressure decreased in patients with lower sodium intake (between-group difference: -9 ± 5 mmHg; p = 0.05) without significant differences in symptomatic hypotension or other safety events (p > 0.3 for all).</p><p><strong>Conclusions: </strong>Adherence assessed by 24-hour natriuresis and by the nutritionist was poor. The group allocated to sodium restriction did not show improvement in NT-proBNP. However, patients who achieved a sodium intake < 2500 mg/day appeared to have improvements in NT-proBNP and quality of life without any adverse safety signals.</p><p><strong>Clinicaltrials: </strong>gov Identifier: NCT03351283.</p>","PeriodicalId":9492,"journal":{"name":"Cardiology journal","volume":"30 3","pages":"411-421"},"PeriodicalIF":2.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ca/7d/cardj-30-3-411.PMC10287066.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9699487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Angiography-based coronary flow reserve: The feasibility of automatic computation by artificial intelligence.","authors":"Qiuyang Zhao,&nbsp;Chunming Li,&nbsp;Miao Chu,&nbsp;Juan Luis Gutiérrez-Chico,&nbsp;Shengxian Tu","doi":"10.5603/CJ.a2021.0087","DOIUrl":"https://doi.org/10.5603/CJ.a2021.0087","url":null,"abstract":"<p><strong>Background: </strong>Coronary flow reserve (CFR) has prognostic value in patients with coronary artery disease. However, its measurement is complex, and automatic methods for CFR computation are scarcely available. We developed an automatic method for CFR computation based on coronary angiography and assessed its feasibility.</p><p><strong>Methods: </strong>Coronary angiographies from the Corelab database were annotated by experienced analysts. A convolutional neural network (CNN) model was trained for automatic segmentation of the main coronary arteries during contrast injection. The segmentation performance was evaluated using 5-fold cross-validation. Subsequently, the CNN model was implemented into a prototype software package for automatic computation of the CFR (CFRauto) and applied on a different sample of patients with angiographies performed both at rest and during maximal hyperemia, to assess the feasibility of CFRauto and its agreement with the manual computational method based on frame count (CFRmanual).</p><p><strong>Results: </strong>Altogether, 137,126 images of 5913 angiographic runs from 2407 patients were used to develop and evaluate the CNN model. Good segmentation performance was observed. CFRauto was successfully computed in 136 out of 149 vessels (91.3%). The average analysis time to derive CFRauto was 18.1 ± 10.3 s per vessel. Moderate correlation (r = 0.51, p < 0.001) was observed between CFRauto and CFRmanual, with a mean difference of 0.12 ± 0.53.</p><p><strong>Conclusions: </strong>Automatic computation of the CFR based on coronary angiography is feasible. This method might facilitate wider adoption of coronary physiology in the catheterization laboratory to assess microcirculatory function.</p>","PeriodicalId":9492,"journal":{"name":"Cardiology journal","volume":"30 3","pages":"369-378"},"PeriodicalIF":2.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ac/0c/cardj-30-3-369.PMC10287087.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9704756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Left-anterior descending chronic total occlusion percutaneous coronary intervention complicated by great cardiac vein fistula: An unusual route for intravascular ultrasound guided successful recanalization.","authors":"Roberto Garbo,&nbsp;Ovidio De Filippo,&nbsp;Federico Conrotto,&nbsp;Mauro Pennone","doi":"10.5603/CJ.2023.0038","DOIUrl":"https://doi.org/10.5603/CJ.2023.0038","url":null,"abstract":"","PeriodicalId":9492,"journal":{"name":"Cardiology journal","volume":"30 3","pages":"489-490"},"PeriodicalIF":2.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d9/12/cardj-30-3-489.PMC10287085.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9711524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Time to -30°C as a predictor of acute success during cryoablation in patients with atrial fibrillation.","authors":"Carlos Antonio Álvarez-Ortega,&nbsp;Miguel Angel Ruiz,&nbsp;César Solórzano-Guillén,&nbsp;Alberto Barrera,&nbsp;Jorge Toquero-Ramos,&nbsp;Jesús Daniel Martínez-Alday,&nbsp;Carlos Grande,&nbsp;José M Segura,&nbsp;Arcadio García-Alberola,&nbsp;Pablo Moriña-Vázquez,&nbsp;Ángel Ferrero-de-Loma-Osorio,&nbsp;Roger Villuendas,&nbsp;Cózar Rocío,&nbsp;Maria Fe Arcocha,&nbsp;Alicia Ibañez,&nbsp;Rafael Peinado","doi":"10.5603/CJ.a2021.0135","DOIUrl":"10.5603/CJ.a2021.0135","url":null,"abstract":"<p><strong>Background: </strong>Freezing rate of second-generation cryoballoon (CB) is a biophysical parameter that could assist pulmonary vein isolation. The aim of this study is to assess freezing rate (time to reach -30°C ([TT-30C]) as an early predictor of acute pulmonary vein isolation using the CB.</p><p><strong>Methods: </strong>Biophysical data from CB freeze applications within a multicenter, nation-wide CB ablation registry were gathered. Successful application (SA), was defined as achieving durable intraprocedural vein isolation. And SA with time to isolation under 60 s (SA-TTI<60) as achieving durable vein isolation in under 60 s. Logistic regressions were performed and predictive models were built for the data set.</p><p><strong>Results: </strong>12,488 CB applications from 1,733 atrial fibrillation (AF) ablation procedures were included within 27 centers from a Spanish CB AF ablation registry. SA was achieved in 6,349 of 9,178 (69.2%) total freeze applications, and SA-TTI<60 was obtained in 2,673 of 4,784 (55.9%) freezes where electrogram monitoring was present. TT-30C was shorter in the SA group (33.4 ± 9.2 vs 39.3 ± 12.1 s; p < 0.001) and SA-TTI<60 group (31.8 ± 7.6 vs. 38.5 ± 11.5 s; p < 0.001). Also, a 10 s increase in TT-30C was associated with a 41% reduction in the odds for an SA (odds ratio [OR] 0.59; 95% confidence interval [CI] 0.56-0.63) and a 57% reduction in the odds for achieving SA-TTI<60 (OR 0.43; 95% CI 0.39-0.49), when corrected for electrogram visualization, vein position, and application order.</p><p><strong>Conclusions: </strong>Time to reach -30°C is an early predictor of the quality of a CB application and can be used to guide the ablation procedure even in the absence of electrogram monitoring.</p>","PeriodicalId":9492,"journal":{"name":"Cardiology journal","volume":"30 4","pages":"534-542"},"PeriodicalIF":2.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d6/37/cardj-30-4-534.PMC10508066.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10201907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}