Cardiology journal最新文献

{"title":"Inhibitors of sodium-glucose transport protein 2: A new multidirectional therapeutic option for heart failure patients.","authors":"Jacek Kubica,&nbsp;Aldona Kubica,&nbsp;Klaudyna Grzelakowska,&nbsp;Wioleta Stolarek,&nbsp;Zofia Grąbczewska,&nbsp;Piotr Michalski,&nbsp;Piotr Niezgoda,&nbsp;Stanisław Bartuś,&nbsp;Andrzej Budaj,&nbsp;Mariusz Dąbrowski,&nbsp;Jarosław Drożdż,&nbsp;Ryszard Gellert,&nbsp;Miłosz Jaguszewski,&nbsp;Piotr Jankowski,&nbsp;Jacek Legutko,&nbsp;Maciej Lesiak,&nbsp;Przemysław Leszek,&nbsp;Jolanta Małyszko,&nbsp;Przemysław Mitkowski,&nbsp;Jadwiga Nessler,&nbsp;Krzysztof Pawlaczyk,&nbsp;Jolanta Siller-Matula,&nbsp;Tomasz Stompór,&nbsp;Bogumił Wolnik,&nbsp;Eliano Pio Navarese","doi":"10.5603/CJ.a2021.0133","DOIUrl":"https://doi.org/10.5603/CJ.a2021.0133","url":null,"abstract":"<p><p>Several mechanisms have been suggested to explain positive cardiovascular effects observed in studies with sodium-glucose co-transporter 2 (SGLT2) inhibitors. The reduction in glucose reabsorption in proximal tubuli induced by SGLT2 inhibitors increases urinary glucose and sodium excretion resulting in increased osmotic diuresis and consequently in decreased plasma volume, followed by reduced preload. In addition, the hemodynamic effects of SGLT2 inhibition were observed in both hyper and euglycemic patients. Due to the complex and multidirectional effects induced by SGLT2 inhibitors, this originally antidiabetic group of drugs has been successfully used to treat patients with heart failure as well as for subjects with chronic kidney disease. Moreover, their therapeutic potential seems to be even broader than the indications studied to date.</p>","PeriodicalId":9492,"journal":{"name":"Cardiology journal","volume":"30 1","pages":"143-149"},"PeriodicalIF":2.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/bc/c4/cardj-30-1-143.PMC9987542.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10856770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immature platelet fraction in cardiovascular diagnostics and antiplatelet therapy monitoring.","authors":"Karolina Gumiężna, Piotr Baruś, Grażyna Sygitowicz, Agnieszka Wiśniewska, Dorota Ochijewicz, Karolina Pasierb, Dominika Klimczak-Tomaniak, Ewa Kuca-Warnawin, Janusz Kochman, Marcin Grabowski, Grzegorz Opolski, Mariusz Tomaniak, Krzysztof J Filipiak","doi":"10.5603/CJ.a2023.0019","DOIUrl":"10.5603/CJ.a2023.0019","url":null,"abstract":"<p><p>Immature platelet fraction (IPF), circulating platelets still containing RNA, can be easily calculated by automated flow cytometry, this makes them an accessible biomarker. Higher IPF concentrations were reported in patients with thrombocytopenia, patients who were smokers, and also those who were diabetics. Several studies have reported their diagnostic and prognostic importance in patients presenting with acute coronary syndromes, especially ST-segment elevation myocardial infarction, where increased IPF level is an independent predictor of cardiovascular death. In addition, higher IPF were reported in patients with inadequate response to either clopidogrel or prasugrel, suggesting their potential role in antiplatelet therapy monitoring. Their prognostic significance was also observed in both coronary artery disease and postcardiac surgery status, where their higher levels correlated with the risk of major adverse cardiac events. The current review aims to present the current evidence on diagnostic, prognostic and potentially therapeutic roles of IPF in cardiovascular medicine.</p>","PeriodicalId":9492,"journal":{"name":"Cardiology journal","volume":" ","pages":"817-824"},"PeriodicalIF":2.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635728/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9092518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiac exercise imaging using a 3-tesla magnetic resonance-conditional pedal ergometer: Preliminary results in healthy volunteers and patients with known or suspected coronary artery disease.","authors":"Agnes Mayr,&nbsp;Gert Klug,&nbsp;Sebastian J Reinstadler,&nbsp;Regina Esterhammer,&nbsp;Christian Kremser,&nbsp;Klemens Mairer,&nbsp;Bernhard Metzler,&nbsp;Michael F Schocke","doi":"10.5603/CJ.a2021.0095","DOIUrl":"https://doi.org/10.5603/CJ.a2021.0095","url":null,"abstract":"<p><strong>Background: </strong>Cardiac magnetic resonance imaging (CMR) remains underutilized as an exercise imaging modality, mostly because of the limited availability of MR-compatible exercise equipment. This study prospectively evaluates the clinical feasibility of a newly developed MR-conditional pedal ergometer for exercise CMR METHODS: Ten healthy volunteers (mean age 44 ± 16 years) and 11 patients (mean age 60 ± 9 years) with known or suspected coronary artery disease (CAD) underwent rest and post-exercise cinematic 3T CMR. Visual analysis of wall motion abnormalities (WMA) was rated by 2 experienced radiologists, and volumes and ejection fractions (EF) were determined. Image quality was assessed by a 4-point Likert scale for visibility of endocardial borders.</p><p><strong>Results: </strong>Median subjective image quality of real-time cine at rest was 1 (interquartile range [IQR] 1-2) and 2 (IQR 2-2.5) for post-exercise real-time cine (p = 0.001). Exercise induced a significant increase in heart rate (62 [62-73] to 111 [104-143] bpm, p < 0.0001). Stroke volume and cardiac index increased from resting to post-exercise conditions (85 ± 21 to 101 ± 19 mL and 2.9 ± 0.7 to 6.6 ± 1.9 L/min/m2, respectively; both p < 0.0001), driven by a reduction in end-systolic volume (55 ± 20 to 42 ± 21 mL, p < 0.0001). Patients (2/11) with inducible regional WMA at high-resolution postexercise cine imaging revealed significant coronary artery stenosis in subsequently performed invasive coronary angiography.</p><p><strong>Conclusions: </strong>Exercise-CMR using our newly developed 3T MR-conditional pedal ergometer is clinically feasible. Imaging of both cardiac response and myocardial ischemia, triggered by dynamic stress, is rapidly conducted while the patient is near their peak heart rate.</p>","PeriodicalId":9492,"journal":{"name":"Cardiology journal","volume":"30 2","pages":"276-285"},"PeriodicalIF":2.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/25/1d/cardj-30-2-276.PMC10129251.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9400961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"\"Burying\" covered coronary stents under drug-eluting stents: A novel approach to ensure long-term stent patency.","authors":"Matthias Bossard,&nbsp;Giacomo Maria Cioffi,&nbsp;Mustafa Yildirim,&nbsp;Federico Moccetti,&nbsp;Mathias Wolfrum,&nbsp;Adrian Attinger,&nbsp;Stefan Toggweiler,&nbsp;Richard Kobza,&nbsp;Florim Cuculi","doi":"10.5603/CJ.a2021.0096","DOIUrl":"https://doi.org/10.5603/CJ.a2021.0096","url":null,"abstract":"<p><strong>Background: </strong>Covered coronary stent (CS) implantation is associated with a high risk for in-stent restenosis (ISR) and stent thrombosis (ST). We describe the outcomes after overstenting (\"burying\") CS using contemporary drug-eluting stents (DES).</p><p><strong>Methods: </strong>We analyzed short- and long-term outcomes of consecutive patients who had had a CS implanted, which was consecutively covered (\"buried\") with a third-generation DES. CSs were primarily post-dilated and then covered with a longer DES overlapping the proximal and distal edges of the CS. To ensure optimal stent expansion and appositions, all lesions were post-dilated using adequately sized non-compliant balloons.</p><p><strong>Results: </strong>Between 2015 and 2020, 23 patients (mean age 67 ± 14 years, 74% males) were treated using this novel approach. Reasons for implanting CS included treatment of coronary aneurysms (n = 7; 30%), coronary perforations (n = 13; 57%), and aorto-ostial dissections (n = 3; 13%). All CSs were successfully deployed, and no peri-procedural complications occurred. The median time of follow-up was 24.5 (interquartile range [IQR] 11.7-37.9) months. All patients had a 1-month follow-up (FU) and 19/23 (83%) patients had 12-month FU (FU range 1-60 months). No probable or definite STs occurred, and no cardiovascular deaths were observed. Among patients undergoing angiographic FU (11/23 [48%]), 1/23 showed angiographically significant ISR 6 months post CS implantation.</p><p><strong>Conclusions: </strong>Burying a coronary CS under a DES appears to be a safe and promising strategy to overcome the limitations of the currently available CS devices, including a relatively high risk for target lesion failure due to ISR and ST.</p>","PeriodicalId":9492,"journal":{"name":"Cardiology journal","volume":"30 2","pages":"196-203"},"PeriodicalIF":2.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a5/46/cardj-30-2-196.PMC10129266.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9400963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"About vegetation size and its clinical implications.","authors":"Isidre Vilacosta","doi":"10.5603/CJ.2023.0008","DOIUrl":"https://doi.org/10.5603/CJ.2023.0008","url":null,"abstract":"This article is available in open access under Creative Common Attribution-Non-Commercial-No Derivatives 4.0 International (CC BY-NC-ND 4.0) license, allowing to download articles and share them with others as long as they credit the authors and the publisher, but without permission to change them in any way or use them commercially. Cardiology Journal 2023, Vol. 30, No. 1, 3–5 DOI: 10.5603/CJ.2023.0008 Copyright © 2023 Via Medica ISSN 1897–5593 eISSN 1898–018X EDITORIAL CLINICAL CARDIOLOGY","PeriodicalId":9492,"journal":{"name":"Cardiology journal","volume":"30 1","pages":"3-5"},"PeriodicalIF":2.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a0/3f/cardj-30-1-3.PMC9987551.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9423926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mindfulness-based emotional regulation for patients with implantable cardioverter-defibrillators: A randomized pilot study of efficacy, applicability, and safety.","authors":"Santiago Montero Ruiz,&nbsp;Beatriz Rodriguez Vega,&nbsp;Carmen Bayón Pérez,&nbsp;Rafael Peinado Peinado","doi":"10.5603/CJ.a2021.0094","DOIUrl":"https://doi.org/10.5603/CJ.a2021.0094","url":null,"abstract":"<p><strong>Background: </strong>The efficacy of mindfulness-based interventions to reduce anxiety or improve quality of life (QoL) in patients with cardiac pathologies is well established. However, there is scarce information on the efficacy, applicability, and safety of these interventions in adult patients with an implantable cardioverter-defibrillator (ICD). In this study, we examined their efficacy on QoL, psychological and biomedical variables, as well as the applicability and safety of a mindfulness-based intervention in patients with an ICD.</p><p><strong>Methods: </strong>Ninety-six patients with an ICD were randomized into two intervention groups and a control group. The interventions involved training in mindfulness-based emotional regulation, either face-to- -face or using the \"REM Volver a casa\" mobile phone application (app).</p><p><strong>Results: </strong>The sample presented medium-high QoL baseline scores (mean: 68), low anxiety (6.84) and depression (3.89), average mindfulness disposition (128), and cardiological parameters similar to other ICD populations. After the intervention, no significant differences were found in the variables studied between the intervention and control groups. Retention was average (59%), and there were no adverse effects due to the intervention.</p><p><strong>Conclusions: </strong>After training in mindfulness-based emotional regulation (face-to-face or via app), no significant differences were found in the QoL or psychological or biomedical variables in patients with an ICD. The intervention proved to be safe, with 59% retention.</p>","PeriodicalId":9492,"journal":{"name":"Cardiology journal","volume":"30 3","pages":"401-410"},"PeriodicalIF":2.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/78/4c/cardj-30-3-401.PMC10287067.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9699485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of long-term clinical outcomes among zotarolimus-, everolimus-, and biolimus-eluting stents in acute myocardial infarction patients with renal impairment.","authors":"Seok Oh, Dae Young Hyun, Kyung Hoon Cho, Ju Han Kim, Myung Ho Jeong","doi":"10.5603/CJ.a2021.0099","DOIUrl":"10.5603/CJ.a2021.0099","url":null,"abstract":"<p><strong>Background: </strong>It is important to determine the best drug-eluting stent (DES) for acute myocardial infarction (AMI) in patients with renal impairment. In this studythe outcomes of everolimus-eluting stents (EESs), zotarolimus-eluting stents (ZESs) and biolimus-eluting stents (BESs) were evaluated.</p><p><strong>Methods: </strong>From the Korea Acute Myocardial Infarction-National Institutes of Health registry, a total of 1,470 AMI patients with renal impairment undergoing percutaneous coronary intervention (PCI) were enrolled (816 with EES, 345 with ZES, and 309 with BES). Renal impairment was defined as creatinine clearance < 60 mL/min/1.73 m² estimated by the Cockcroft-Gault method. Major adverse cardiac and cerebrovascular events were determined as the composite of all-cause death, non-fatal myocardial infarction (MI), cerebrovascular accident, any revascularization, rehospitalization and stent thrombosis. All clinical outcomes were analyzed.</p><p><strong>Results: </strong>The baseline characteristics of the patients revealed no significant difference between the three groups, except for Killip classification > 2, beta-blockers, lesion type, vascular approach, staged PCI, left main coronary artery (LMCA) complex lesions, LMCA PCI, and the number and length of implanted stents. In the Kaplan-Meier analysis, similar clinical outcomes were derived from the unadjusted data between the three DES groups. However, after the inverse probability of treatment weighting, a statistically significant difference was found in non-fatal MI, which implied a higher incidence of non-fatal MI in the ZES group than in the other two DES groups.</p><p><strong>Conclusions: </strong>In AMI patients with renal impairment, there was no significant difference between the three stent groups in terms of long-term clinical outcomes, except for non-fatal MI.</p>","PeriodicalId":9492,"journal":{"name":"Cardiology journal","volume":"30 3","pages":"440-452"},"PeriodicalIF":2.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/66/3e/cardj-30-3-440.PMC10287071.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9699488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isolated persistent left superior vena cava: A rare and unexpected finding in a patient with COVID-19 and complete heart block.","authors":"Dawid Miśkowiec,&nbsp;Paweł Życiński,&nbsp;Haval D Qawoq,&nbsp;Jarosław D Kasprzak","doi":"10.5603/CJ.2023.0020","DOIUrl":"https://doi.org/10.5603/CJ.2023.0020","url":null,"abstract":"Contained in this report is the case of a 90-year-old man with a loss of consciousness, fe - ver and cough. The electrocardiogram showed third degree atrio-ventricular block with 30 bpm ven - tricular escape rhythm, with no reversible causes. A transvenous pacing was attempted and after positive SARS-CoV-2 PCR he was transferred to a referral hospital with a “COVID-Cardiology” unit. Transthoracic echocardiography (TTE) showed preserved left ventricular systolic function and dilated coronary sinus (CS). D-dimer was elevated and the computed tomography (CT) pulmonary an - giogram showed subsegmental pulmonary emboli, without typical COVID-19 pneumonia. The patient underwent pacemaker (PCM)","PeriodicalId":9492,"journal":{"name":"Cardiology journal","volume":"30 2","pages":"327-328"},"PeriodicalIF":2.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/bf/ee/cardj-30-2-327.PMC10129254.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9403598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Shockwave intravascular lithotripsy as a novel strategy for balloon undilatable heavily calcified chronic total occlusion lesions.","authors":"Piotr Rola, Adrian Włodarczak, Mateusz Barycki, Maciej Pęcherzewski, Jan Jakub Kulczycki, Marek Szudrowicz, Artur Jastrzębski, Łukasz Furtan, Adrian Doroszko, Maciej Lesiak","doi":"10.5603/CJ.a2021.0112","DOIUrl":"10.5603/CJ.a2021.0112","url":null,"abstract":"<p><strong>Background: </strong>The successful percutaneous coronary intervention (PCI) in chronic total occlusion (CTO) improves the long-term outcome in patients with coronary artery disease (CAD). Heavy calcification remains one of the strongest predictors of an unfavorable outcome of PCI. In this case series study, shockwave intravascular lithotripsy (S-IVL)-a novel balloon-based coronary system facilitating modification of calcified coronary lesions was evaluated.</p><p><strong>Methods: </strong>The study population consisted of five heavily calcified, undilatable-CTOs lesions treated with S-IVL selected out of all consecutive CTO-PCI patients performed at two high-volume cardiac centers.</p><p><strong>Results: </strong>The registry included 5 patients successful CTO - S-IVL procedures with an average J-CTO of 2.6 points. In the short-term follow-up period, including the first 30 days, no cases of acute in-stent thrombosis, target lesion failure, or major adverse cardiac and cerebrovascular events were noted.</p><p><strong>Conclusions: </strong>The present data suggest that this approach can be safe and useful in the treatment of complex calcified CTO lesions.</p>","PeriodicalId":9492,"journal":{"name":"Cardiology journal","volume":" ","pages":"677-684"},"PeriodicalIF":2.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635730/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39464518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of reorganized versus unaltered cardiology departments during the COVID-19 era: A subanalysis of the COV-HF-SIRIO 6 study.","authors":"Małgorzata Ostrowska, Michał Kasprzak, Wioleta Stolarek, Klaudyna Grzelakowska, Jacek Kryś, Aldona Kubica, Piotr Adamski, Przemysław Podhajski, Eliano Pio Navarese, Edyta Anielska-Michalak, Oliwia Matuszewska-Brycht, Andrzej Curzytek, Aneta Dudek, Leszek Gromadziński, Paweł Grzelakowski, Leszek Kamiński, Andrzej Kleinrok, Marcin Kostkiewicz, Marek Koziński, Paweł Król, Tomasz Kulawik, Gleb Minczew, Marcin Mindykowski, Agnieszka Pawlak, Janusz Prokopczuk, Grzegorz Skonieczny, Bożena Sobkowicz, Sergiusz Sowiński, Sebastian Stankala, Paweł Szymański, Andrzej Wester, Przemysław Wilczewski, Stanisław Bartuś, Andrzej Budaj, Robert Gajda, Mariusz Gąsior, Marcin Gruchała, Jarosław Drożdż, Miłosz Jaguszewski, Piotr Jankowski, Jacek Legutko, Maciej Lesiak, Przemysław Leszek, Przemysław Mitkowski, Jadwiga Nessler, Anna Tomaszuk-Kazberuk, Agnieszka Tycińska, Tomasz Zdrojewski, Jarosław Kaźmierczak, Jacek Kubica","doi":"10.5603/CJ.a2023.0002","DOIUrl":"10.5603/CJ.a2023.0002","url":null,"abstract":"<p><strong>Background: </strong>Since the beginning of the coronavirus disease 2019 (COVID-19) pandemic, numerous cardiology departments were reorganized to provide care for COVID-19 patients. We aimed to compare the impact of the COVID-19 pandemic on hospital admissions and in-hospital mortality in reorganized vs. unaltered cardiology departments.</p><p><strong>Methods: </strong>The present research is a subanalysis of a multicenter retrospective COV-HF-SIRIO 6 study that includes all patients (n = 101,433) hospitalized in 24 cardiology departments in Poland between January 1, 2019 and December 31, 2020, with a focus on patients with acute heart failure (AHF).</p><p><strong>Results: </strong>Reduction of all-cause hospitalizations was 50.6% vs. 21.3% for reorganized vs. unaltered cardiology departments in 2020 vs. 2019, respectively (p < 0.0001). Considering AHF alone respective reductions by 46.5% and 15.2% were registered (p < 0.0001). A higher percentage of patients was brought in by ambulance to reorganized vs. unaltered cardiology departments (51.7% vs. 34.6%; p < 0.0001) alongside with a lower rate of self-referrals (45.7% vs. 58.4%; p < 0.0001). The rate of all-cause in-hospital mortality in AHF patients was higher in reorganized than unaltered cardiology departments (10.9% vs. 6.4%; p < 0.0001). After the exclusion of patients with concomitant COVID-19, the mortality rates did not differ significantly (6.9% vs. 6.4%; p = 0.55).</p><p><strong>Conclusions: </strong>A greater reduction in hospital admissions in 2020 vs. 2019, higher rates of patients brought by ambulance together with lower rates of self-referrals and higher all-cause in-hospital mortality for AHF due to COVID-19 related deaths were observed in cardiology departments reorganized to provide care for COVID-19 patients vs. unaltered ones.</p>","PeriodicalId":9492,"journal":{"name":"Cardiology journal","volume":"30 3","pages":"344-352"},"PeriodicalIF":2.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/32/3d/cardj-30-3-344.PMC10287078.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9758525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}