Cardiovascular Intervention and Therapeutics最新文献

{"title":"Association between myocardial bridge and upstream plaque morphology in patients with acute coronary syndrome.","authors":"Eisuke Usui, Tatsuhiro Nagamine, Yoshihisa Kanaji, Masahiro Hada, Kai Nogami, Hiroki Ueno, Mirei Setoguchi, Kodai Sayama, Takahiro Watanabe, Hikaru Shimosato, Takashi Mineo, Tomoyo Sugiyama, Taishi Yonetsu, Tetsuo Sasano, Tsunekazu Kakuta","doi":"10.1007/s12928-025-01134-5","DOIUrl":"https://doi.org/10.1007/s12928-025-01134-5","url":null,"abstract":"<p><p>Myocardial bridging (MB), characterized by systolic coronary artery compression, alters coronary flow and may influence upstream atherosclerotic plaque morphology. We aimed to investigate the relationship between MB and morphological features of upstream culprit plaques in patients with acute coronary syndrome (ACS). We retrospectively analyzed 370 ACS patients who underwent optical coherence tomography (OCT)-guided PCI for a de novo culprit lesion in the proximal left anterior descending artery (LAD). OCT images identified plaque rupture (PR), classifying lesions into PR and intact fibrous cap (IFC) groups. The IFC group was further divided based on the presence of lipid-rich plaque (LRP), defined as a plaque with a maximum lipid angle > 90°. This study included 370 ACS patients (mean age 65.2 ± 12.3 years, 82.4% male). Angiographic evidence of MB was present in 8.6% (32/370) of patients prior to PCI and increased to 17.0% (63/370) post-PCI; all MBs identified pre-PCI were also observed post-PCI. OCT identified 213 lesions with plaque rupture and 157 lesions with IFC (of which 83 exhibited underlying LRP and 74 did not). The prevalence of post-PCI angiographically detected MB differed significantly among the OCT-defined morphological groups: 11.3% (24/213) in the PR group, 18.1% (15/83) in the IFC-LRP group, and 32.4% (24/74) in the IFC-non-LRP group (P < 0.01). No periprocedural myocardial injury occurred in the IFC-non-LRP group. In patients with ACS, the presence of MB was significantly associated with a lower likelihood of plaque rupture and LRP in the upstream culprit lesion as assessed by OCT.</p>","PeriodicalId":9439,"journal":{"name":"Cardiovascular Intervention and Therapeutics","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144118925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship between chronic expansion of self-expandable valves and paravalvular leakage in transcatheter aortic valve implantation.","authors":"Yuuki Muto, Daisuke Isomatsu, Yu Sato, Akihiko Sato, Takeshi Shimizu, Tomofumi Misaka, Masayoshi Oikawa, Atsushi Kobayashi, Akiomi Yoshihisa, Kazuhiko Nakazato, Takafumi Ishida, Hirofumi Sekino, Kenji Fukushima, Hiroshi Ito, Yasuchika Takeishi","doi":"10.1007/s12928-025-01140-7","DOIUrl":"https://doi.org/10.1007/s12928-025-01140-7","url":null,"abstract":"<p><p>Paravalvular leakage (PVL) is a clinical concern in transcatheter aortic valve implantation (TAVI). Although PVL has been reported to gradually decrease after self-expandable valves (SEVs) implantation, the mechanism remains unclear. Furthermore, while gradual expansion of SEVs has been documented, studies assessing their morphological changes during the chronic phase are lacking. This study aims to evaluate whether SEVs expansion occurs during follow-up and if this expansion correlates with a reduction in PVL. We included 60 patients who underwent TAVI using SEVs (Evolut PRO/PRO+/FX) from October 2020 to August 2024. Morphological findings of SEVs were assessed using computed tomography (CT), and PVL was evaluated at discharge and chronic phase post-TAVI. PVL was graded on a five-point scale via transthoracic echocardiography, and the area ratio, defined as the ratio of the basal area of the implanted SEVs to that of phantom valves measured by CT, served as the index of SEVs expansion. Chronic expansion of SEVs was observed in all cases, with the area ratio increasing from 0.59 at discharge to 0.64 at the follow-up (P < 0.05). Among the 60 patients, 44 exhibited mild or greater PVL, with 17 showing improvement at the chronic phase. The degree of valve expansion (area ratio at chronic phase/area ratio at discharge) was significantly greater in the PVL improvement group compared to the non-improvement group (1.11 vs. 1.06, P < 0.05). This study demonstrates that SEVs expand during the chronic phase after TAVI, which could contribute to the reduction of PVL.</p>","PeriodicalId":9439,"journal":{"name":"Cardiovascular Intervention and Therapeutics","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144109771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radial artery approach for treating right posterior tibial artery stenosis and bilateral SFA lesions in a single procedure.","authors":"Arata Sano, Takeshi Sugimoto, Tomoya Iwasaki, Noriyuki Wakana, Hiroyuki Yamada, Satoaki Matoba","doi":"10.1007/s12928-025-01141-6","DOIUrl":"https://doi.org/10.1007/s12928-025-01141-6","url":null,"abstract":"","PeriodicalId":9439,"journal":{"name":"Cardiovascular Intervention and Therapeutics","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144109769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancement of posterior mitral leaflet imaging quality during the MitraClip procedure using one-lung ventilation.","authors":"Masafumi Sato, Kenji Harada, Koichi Yoshinaga, Koichiro Seki, Koji Kawahito, Kazuomi Kario","doi":"10.1007/s12928-025-01138-1","DOIUrl":"https://doi.org/10.1007/s12928-025-01138-1","url":null,"abstract":"","PeriodicalId":9439,"journal":{"name":"Cardiovascular Intervention and Therapeutics","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144086086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An unexpected nightmare: a graft perforation after implantation of Viabahn^® VBX covered stent for iliac artery rupture.","authors":"Tomoya Hasegawa, Shusaku Maruyama, Takahiro Tachibana, Hikaru Kimura","doi":"10.1007/s12928-025-01139-0","DOIUrl":"https://doi.org/10.1007/s12928-025-01139-0","url":null,"abstract":"","PeriodicalId":9439,"journal":{"name":"Cardiovascular Intervention and Therapeutics","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dual-Prep registry: atherectomy devices and intravascUlAr lithotripsy for the PREParation of heavily calcified coronary lesions registry.","authors":"Masato Nakamura, Nehiro Kuriyama, Yutaka Tanaka, Seiji Yamazaki, Tomohiro Kawasaki, Takashi Muramatsu, Kazushige Kadota, Takashi Ashikaga, Akihiko Takahashi, Satoru Otsuji, Kenji Ando, Masaru Ishida, Shigeru Nakamura, Yoshiaki Ito, Raisuke Iijima, Gaku Nakazawa, Junya Shite, Junko Honye, Junya Ako, Hiroyoshi Yokoi, Ken Kozuma, Hiromasa Otake, Kazuho Masumura, Tomomi Yamada, Yohei Sotomi","doi":"10.1007/s12928-025-01130-9","DOIUrl":"https://doi.org/10.1007/s12928-025-01130-9","url":null,"abstract":"<p><p>Evaluation of calcified lesions by intravascular imaging has revealed that atherectomy devices have only limited impact. However, subsequent use of coronary intravascular lithotripsy (IVL) may increase treatment effectiveness without increasing risk of complications. This study was designed to evaluate the safety and effectiveness of IVL use after atherectomy in severely calcified coronary lesions as pre-treatment for drug-eluting stents (DES). The Dual-Prep registry is a multicenter, prospective registry of consecutive image-guided percutaneous coronary interventions (PCI). The primary effectiveness and safety endpoints were procedural success (residual stenosis < 50% by quantitative coronary angiography) without an in-hospital major adverse cardiac event (MACE) and 30-day freedom from MACE, respectively. Baseline vessel calcification score and final DES expansion were evaluated by optical coherence tomography (OCT). A total of 118 patients with 120 lesions were enrolled at 20 sites. The calcification score of lesions after atherectomy by core-lab assessment was 4.0 in all cases. Rotational atherectomy was applied prior to IVL in 83.9% cases with mean burr size of 1.57 ± 0.20 mm; IVL was subsequently successfully delivered in all cases (mean balloon diameter 3.02 ± 0.45 mm), followed by DES deployment (mean diameter 3.19 ± 0.51 mm, length of 36.3 ± 16.0 mm). The primary efficacy and safety endpoints were met in 98.3% and 98.3% of cases, respectively. A DES expansion index < 0.8 was seen in 42.2%, and an eccentricity index < 0.7 was not observed in any patient. In severely calcified lesions, image-guided atherectomy followed by IVL lesion preparation demonstrated high procedural success rates and satisfactory non-eccentric stent expansion. This approach may be considered for lesions where an 'IVL-first' strategy may not be feasible. jRCT1032230384 (Oct 7, 2023).</p>","PeriodicalId":9439,"journal":{"name":"Cardiovascular Intervention and Therapeutics","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143977111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cerebral embolic protection in transcatheter aortic valve implantation (TAVI): a pooled analysis of 4091 patients.","authors":"Mahmoud Balata, Mohamed Ibrahim Gbreel, Mohamed Hamouda Elkasaby, Ahmed Samy Badran, Marwa Hassan, Ralf Westenfeld, Roman Pfister, Sebastian Zimmer, Marc Ulrich Becher, Georg Nickenig, Atsushi Sugiura","doi":"10.1007/s12928-025-01128-3","DOIUrl":"https://doi.org/10.1007/s12928-025-01128-3","url":null,"abstract":"<p><strong>Background: </strong>Transcatheter aortic valve implantation (TAVI) is increasingly used for severe aortic stenosis, but debris embolization during the procedure can lead to strokes, impacting survival and quality of life. The role of cerebral embolic protection devices (CEPDs) in mitigating stroke risk remains debated. We aim to evaluate the impact of CEPDs on the risk of stroke and neurocognitive outcomes after TAVI.</p><p><strong>Methods: </strong>Six databases (PubMed, Scopus, Web of Science, Cochrane, Embase, and Ovid) were searched until 20 January 2023. Original randomized controlled trials (RCTs) were only included and critically appraised using the Cochrane risk of bias (ROB) tool.</p><p><strong>Results: </strong>Seven RCTs (4091 patients) were analyzed. CEPDs significantly reduced the risk of disabling stroke within 2-5 days post-TAVI (relative risk = 0.455, 95% CI: [0.214, 0.967]; p = 0.041). However, there was no significant difference in disabling stroke risk between the two groups at the 30-day follow-up (relative risk = 1.295, 95% CI: [0.373, 4.493]; p = 0.684). No significant differences were observed in non-disabling or overall stroke rates at 2-5 days, 30 days, or 90 days. Additionally, CEPDs did not significantly affect risks of life-threatening bleeding, major vascular complications, mortality, or acute kidney injury.</p><p><strong>Conclusion: </strong>CEPDs are effective in reducing disabling stroke risk in the immediate post-TAVI period (2-5 days) but did not significantly affect the rates of non-disabling stroke, overall stroke, or disabling stroke after 30 days when compared to non-CEPD use. These findings suggest that CEPDs may offer short-term neuroprotection.</p>","PeriodicalId":9439,"journal":{"name":"Cardiovascular Intervention and Therapeutics","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143974543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Limb salvage using mechanical aspiration thrombectomy in super-elderly patients with acute limb ischemia due to popliteal artery aneurysm.","authors":"Yusuke Tomoi, Yoshimitsu Soga, Taichi Hirano, Kazuki Tsunoda, Kenji Ando","doi":"10.1007/s12928-025-01132-7","DOIUrl":"https://doi.org/10.1007/s12928-025-01132-7","url":null,"abstract":"","PeriodicalId":9439,"journal":{"name":"Cardiovascular Intervention and Therapeutics","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143970652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility and safety of the distal radial access for vascular access interventional therapy.","authors":"Koji Kuroda, Ayaka Murakami, Takafumi Todoroki, Masamichi Iwasaki, Junichi Imanishi, Souichiro Yamashita, Wataru Fujimoto, Makoto Takemoto, Masanori Okuda","doi":"10.1007/s12928-025-01127-4","DOIUrl":"https://doi.org/10.1007/s12928-025-01127-4","url":null,"abstract":"<p><p>Distal radial access (DRA) has emerged as an alternative approach to reduce the risk of radial artery occlusion in coronary angiography. Vascular access intervention therapy (VAIVT) is traditionally used to treat arteriovenous fistula stenosis. However, the feasibility and safety of DRA for VAIVT have not been established. This study aimed to evaluate the feasibility and safety of using DRA for VAIVT. We included 421 consecutive VAIVT procedures for upper limb arteriovenous fistulas retrospectively. DRA for VAIVT was performed in 181 procedures (DRA group), and the remaining procedures were approached through the brachial artery or vein (SA group: standard access group). Clinical follow-up was performed to evaluate the incidence of hematoma and dialysis access-associated steal syndrome (DASS). The mean follow-up duration following VAIVT was 24.0 months. The VAIVT success rate did not differ significantly between the groups (DRA: 97.8% vs. SA: 98.3%; P = 0.73), neither did the incidence of puncture site hematoma (DRA: 0.0% vs. SA: 0.8%; P = 0.51). There were no complications with DASS symptoms in the DRA group during the clinical follow-up. In the DRA group, 90 patients underwent a subsequent VAIVT procedure, and 85 patients (94.4%) underwent a subsequent VAIVT by DRA. DRA is a feasible and safe strategy for VAIVT and could be considered an option for VAIVT.</p>","PeriodicalId":9439,"journal":{"name":"Cardiovascular Intervention and Therapeutics","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143989914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of very early-phase vascular response to the CD34 antibody‑covered sirolimus‑eluting stent versus durable polymer-coated everolimus-eluting stent.","authors":"Hiroki Goto, Hideki Kitahara, Tadahiro Matsumoto, Kazuya Tateishi, Yuichi Saito, Ken Kato, Yoshio Kobayashi","doi":"10.1007/s12928-025-01114-9","DOIUrl":"https://doi.org/10.1007/s12928-025-01114-9","url":null,"abstract":"<p><p>The COMBO stent is a unique biodegradable polymer sirolimus-eluting stent with an anti-CD34 antibody coating that captures endothelial progenitor cells and potentially promotes vessel healing. There are limited data regarding strut tissue coverage at the very short-term period after COMBO stent implantation compared to other types of drug-eluting stents in the same patient. This prospective study enrolled patients who had COMBO Plus stent and durable polymer-coated everolimus-eluting stent (XIENCE stent) implanted simultaneously in the same vessel for long coronary lesions. Strut tissue coverage within 1 month after implantation was compared using optical coherence tomography. Struts fully covered with tissue were defined as covered, and healthy tissue coverage was defined as tissue thickness with ≥ 40 μm. A total of 21 patients, 11 (52%) of whom presented with acute coronary syndrome, were enrolled. A total of 4798 struts from 21 COMBO Plus stents and 4608 struts from 21 XIENCE stents were analyzed at an average of 19.8 ± 6.5 days after implantation. In the lesion-level analysis, covered struts were more frequently observed (83.7 ± 7.4% vs. 76.9 ± 11.0%, P < 0.01), and the rate of healthy tissue coverage tended to be higher (49.9 ± 17.7% vs. 42.1 ± 20.5%, P = 0.07) in the COMBO Plus stent compared to the XIENCE stent. Strut tissue coverage was more advanced in the COMBO Plus stent compared to the XIENCE stent at the very short-term period after implantation.</p>","PeriodicalId":9439,"journal":{"name":"Cardiovascular Intervention and Therapeutics","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143983278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}