Cardiovascular Intervention and Therapeutics最新文献_第2页

Comprehensive analysis of acute kidney injury incidence following transcatheter versus surgical aortic valve replacement in aortic stenosis: a systematic review and meta-analysis of 13,777 patients. 主动脉狭窄经导管与手术主动脉瓣置换术后急性肾损伤发生率的综合分析：13777例患者的系统回顾和荟萃分析。

IF 5.8

Cardiovascular Intervention and Therapeutics Pub Date : 2025-10-01 Epub Date: 2025-05-27 DOI: 10.1007/s12928-025-01144-3

Ahmad Alazzam, Yacoub Aldroubi, Tariq Alhusban, Mosab Said

{"title":"Comprehensive analysis of acute kidney injury incidence following transcatheter versus surgical aortic valve replacement in aortic stenosis: a systematic review and meta-analysis of 13,777 patients.","authors":"Ahmad Alazzam, Yacoub Aldroubi, Tariq Alhusban, Mosab Said","doi":"10.1007/s12928-025-01144-3","DOIUrl":"10.1007/s12928-025-01144-3","url":null,"abstract":"This systematic review and meta-analysis evaluate Acute Kidney Injury (AKI) differences between surgical aortic valve replacement (SAVR) and transcatheter aortic valve replacement (TAVR) and how surgical risk stratification and diagnostic criteria influence outcomes. Following the PRISMA guidelines, we included both non-randomized studies and randomized clinical trials that reported AKI criteria and patients' surgical risk in patients with aortic stenosis by searching PubMed, Scopus, and Web of Science until late September. We executed a random-effects model in Review Manager to pool effect estimates of AKI incidence or the need for dialysis as an odds ratio (OR) and I2 heterogeneity, and we utilized R for meta-regression to address any heterogeneity with subgroup analysis for surgical risk, AKI criteria, and study design. We used the Newcastle Ottawa Scale (NOS) and the Cochrane Risk of Bias Tool (RoB-1) for risk of bias assessment and GRADE for certainty assessment. Involving 17 studies and a total of 13,777 patients, we found that the AKI incidence was significantly lower in TAVR compared to SAVR (OR = 0.36; 95% CI: [0.30, 0.44], I2 = 55%, P = 0.003), along with the need for dialysis (OR = 0.35; 95% CI: [0.19, 0.63], I2 = 0%, P = 0.92). The study also found that intermediate and low-risk patients had more favorable outcomes. However, the retrospective study design and VARC-2 criteria were associated with unfavorable outcomes. TAVR effectively reduced the risk of AKI in all surgical risk categories and the need for dialysis compared to SAVR in patients with AS.","PeriodicalId":9439,"journal":{"name":"Cardiovascular Intervention and Therapeutics","volume":" ","pages":"932-942"},"PeriodicalIF":5.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144148943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Feasibility of guiding catheter exchange using extension wire in percutaneous coronary intervention after transcatheter aortic valve replacement. 经导管主动脉瓣置换术后经皮冠状动脉介入治疗中延长丝引导导管置换的可行性。

IF 5.8

Cardiovascular Intervention and Therapeutics Pub Date : 2025-10-01 Epub Date: 2025-06-24 DOI: 10.1007/s12928-025-01159-w

Makoto Saigan, Masaki Miyasaka, Daishi Tazawa, Momo Kosuga, Manabu Maeda, Yun Teng, Natsuko Satomi, Yuta Kobayashi, Masaki Nakashima, Yusuke Enta, Yoshiko Munehisa, Yukihiro Hayatsu, Norio Tada

{"title":"Feasibility of guiding catheter exchange using extension wire in percutaneous coronary intervention after transcatheter aortic valve replacement.","authors":"Makoto Saigan, Masaki Miyasaka, Daishi Tazawa, Momo Kosuga, Manabu Maeda, Yun Teng, Natsuko Satomi, Yuta Kobayashi, Masaki Nakashima, Yusuke Enta, Yoshiko Munehisa, Yukihiro Hayatsu, Norio Tada","doi":"10.1007/s12928-025-01159-w","DOIUrl":"10.1007/s12928-025-01159-w","url":null,"abstract":"Percutaneous coronary intervention (PCI) after transcatheter aortic valve replacement (TAVR) is technically challenging because of the presence of the transcatheter heart valve (THV), which complicates coronary artery engagement. Owing to their flexibility, diagnostic catheters (DCs) facilitate coronary access, but require subsequent exchange to guiding catheters (GCs) for PCI. The feasibility of using an extension wire (EW) to facilitate DC-to-GC exchange in this context remains unexplored. A retrospective analysis was conducted at our institution, examining 11 PCI cases performed after TAVR between January 6, 2020, and June 1, 2024, in which an EW was employed to transition from a DC to a GC. Clinical, angiographic, and procedural data were reviewed. Procedural success was defined as a successful DC-to-GC exchange and completion of PCI. DC-to-GC exchange using an EW was successfully achieved in all 11 cases (100%). Revascularization was achieved in 10/11 cases (91%). The lesions were uniformly classified as American College of Cardiology/American Heart Association Type B2/C. The GCs included Judkins-type in 7/11 cases (64%) and backup-type in 4/11 cases (36%). The THV types included SAPIEN in 6/11 cases (55%), Evolut in 3/11 cases (27%), and Navitor in 2/11 cases (18%). A 6Fr GC was utilized in 10/11 cases (91%), and rotational atherectomy was performed in 1/11 cases (9%). The use of an EW to facilitate the transition from DC to GC in PCI after TAVR resulted in high procedural success, providing a feasible approach for addressing complex lesions and optimizing procedural outcomes.","PeriodicalId":9439,"journal":{"name":"Cardiovascular Intervention and Therapeutics","volume":" ","pages":"820-826"},"PeriodicalIF":5.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144473992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A pilot study on coronary microvascular dysfunction in obstructive hypertrophic cardiomyopathy: impact of percutaneous transluminal septal myocardial ablation. 阻塞性肥厚性心肌病冠状动脉微血管功能障碍的初步研究：经皮腔内间隔心肌消融的影响。

IF 5.8

Cardiovascular Intervention and Therapeutics Pub Date : 2025-10-01 Epub Date: 2025-06-27 DOI: 10.1007/s12928-025-01154-1

Taikan Terauchi, Daigo Hiraya, Kyohei Usami, Takumi Yaguchi, Hiroaki Watabe, Tomoya Hoshi, Tomoko Ishizu

{"title":"A pilot study on coronary microvascular dysfunction in obstructive hypertrophic cardiomyopathy: impact of percutaneous transluminal septal myocardial ablation.","authors":"Taikan Terauchi, Daigo Hiraya, Kyohei Usami, Takumi Yaguchi, Hiroaki Watabe, Tomoya Hoshi, Tomoko Ishizu","doi":"10.1007/s12928-025-01154-1","DOIUrl":"10.1007/s12928-025-01154-1","url":null,"abstract":"Coronary microvascular dysfunction (CMD) is well-characterized in the context of coronary artery disease, but its relationship to obstructive hypertrophic cardiomyopathy (oHCM) is poorly understood. In addition, the impact of percutaneous transluminal septal myocardial ablation (PTSMA) on CMD has not been fully evaluated. Between October 2023 and May 2024, PTSMA was performed on 10 patients with oHCM. A pressure guidewire in the left anterior descending artery (LAD) was used to invasively assess CMD before and after the procedure. Measurements were recorded for resting full-cycle ratio (RFR), fractional flow reserve (FFR), coronary flow reserve (CFR), and index of microcirculatory resistance (IMR). The 10 patients had a median age of 66 [57-75] years, with a resting left ventricular pressure gradient of 44 [17-84] mmHg, measured via catheterization. Prior to PTSMA, the RFR measured in the LAD was 0.93 [0.91-0.96], and the FFR was 0.95 [0.92-0.95], which were both within normal limits. However, the CFR was reduced to 1.8 [1.6-2.1], and the IMR was elevated to 31 [25-39], which indicated CMD. Post-procedure, the left ventricular pressure gradient decreased to 5 [2-8] mmHg, CFR improved to 2.5 [2.2-3.6], and IMR decreased to 22 [17-26], indicating improvement in CMD. In patients with oHCM, myocardial hypertrophy contributes to left ventricular outflow tract obstruction and CMD. This study demonstrated that PTSMA as a septal reduction therapy improved the left ventricular pressure gradient and CMD.","PeriodicalId":9439,"journal":{"name":"Cardiovascular Intervention and Therapeutics","volume":" ","pages":"973-981"},"PeriodicalIF":5.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12432050/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144504894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of aortic angulation on outcomes in transcatheter aortic valve replacement with balloon-expandable and self-expanding valves: a systematic review and meta-analysis. 主动脉成角对经导管主动脉瓣球囊扩张和自扩张瓣膜置换术结果的影响：一项系统综述和荟萃分析。

IF 5.8

Cardiovascular Intervention and Therapeutics Pub Date : 2025-10-01 Epub Date: 2025-07-18 DOI: 10.1007/s12928-025-01169-8

Basma Badrawy Khalefa, Ahmed Reda Gonnah, Mazen Negmeldin Aly Yassin, Hossam Fayed, Moumen Arnaout, Mohamed Karam Allah Elkholy, Mohamed Ramadan, Abdelrahman Mohammed Elettreby, Ali Dway, Hatem Eldeeb, Abdullah Saeed Abujabal, David Hesketh Roberts

{"title":"Impact of aortic angulation on outcomes in transcatheter aortic valve replacement with balloon-expandable and self-expanding valves: a systematic review and meta-analysis.","authors":"Basma Badrawy Khalefa, Ahmed Reda Gonnah, Mazen Negmeldin Aly Yassin, Hossam Fayed, Moumen Arnaout, Mohamed Karam Allah Elkholy, Mohamed Ramadan, Abdelrahman Mohammed Elettreby, Ali Dway, Hatem Eldeeb, Abdullah Saeed Abujabal, David Hesketh Roberts","doi":"10.1007/s12928-025-01169-8","DOIUrl":"10.1007/s12928-025-01169-8","url":null,"abstract":"High aortic angulation (AA) can pose significant challenges during TAVR. This meta-analysis determines the impact of a horizontal aorta on TAVR outcomes with balloon-expandable (BEV) and self-expanding valves (SEVs). A comprehensive search was conducted from inception to June 2024. Thirteen observational studies assessing the impact of aortic angulation in patients undergoing TAVR replacement were included. The pooled results indicated that short-term mortality was significantly lower in patients with a non-horizontal aorta (RR = 0.76; 95% CI 0.62-0.95, P = 0.01). Subgroup analysis displayed that BEVs had a lower short-term mortality with a horizontal aorta than SEVs. The incidence of stroke was not significantly affected by aortic angulation with either valve type. However, the overall risk of permanent pacemaker implantation was lower in patients with a non-horizontal aorta for both valve types. Paravalvular regurgitation was also reduced in the non-horizontal aorta group, with no difference between aortic angulations in patients with BEVs. In contrast, SEVs favored a non-horizontal aorta in reducing paravalvular leak (RR = 0.66; 95% CI 0.46-0.94, P = 0.02). Both BEVs and SEVs show better results in patients with lower aortic root angulation. The increased incidence of conduction abnormalities and PPI rates with both valve types in patients with horizontal aorta is a concern. BEVs could be potentially used preferentially to SEVs in patients with a horizontal aorta as there was no difference between horizontal and non-horizontal aorta groups regarding short-term mortality, moderate-to-severe paravalvular leak, and need for a second valve.","PeriodicalId":9439,"journal":{"name":"Cardiovascular Intervention and Therapeutics","volume":" ","pages":"746-766"},"PeriodicalIF":5.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12431928/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144658432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transcatheter edge-to-edge repair for primary mitral regurgitation caused by an aberrant atrial band. 心房带异常引起的原发性二尖瓣反流的经导管边缘对边缘修复。

IF 5.8

Cardiovascular Intervention and Therapeutics Pub Date : 2025-10-01 Epub Date: 2025-06-26 DOI: 10.1007/s12928-025-01164-z

Kunihiko Shimizu, Takashi Matsumoto, Tomoki Ochiai, Kazuki Tobita, Shingo Mizuno, Shigeru Saito

引用次数: 0

Plaque rupture and calcified nodules: major contributors to out-of-hospital cardiac arrest in acute myocardial infarction. 斑块破裂和钙化结节：急性心肌梗死院外心脏骤停的主要原因。

IF 5.8

Cardiovascular Intervention and Therapeutics Pub Date : 2025-10-01 Epub Date: 2025-06-06 DOI: 10.1007/s12928-025-01146-1

Takato Hirose, Kenichi Fujii, Kenta Hashimoto, Kazunori Bando, Shun Morishita, Masanao Taniichi, Keita Horitani, Ichiro Shiojima

{"title":"Plaque rupture and calcified nodules: major contributors to out-of-hospital cardiac arrest in acute myocardial infarction.","authors":"Takato Hirose, Kenichi Fujii, Kenta Hashimoto, Kazunori Bando, Shun Morishita, Masanao Taniichi, Keita Horitani, Ichiro Shiojima","doi":"10.1007/s12928-025-01146-1","DOIUrl":"10.1007/s12928-025-01146-1","url":null,"abstract":"Since patients with cardiac arrest associated with acute myocardial infarction (MI) may not be successfully resuscitated, the underlying mechanisms of acute MI leading to out-of-hospital cardiac arrest (OHCA) have not been elucidated. This study evaluated whether there are differences in the plaque characteristics of infarct-related lesions between acute MI patients with OHCA and those without OHCA. This study analyzed 604 consecutive patients with a diagnosis of acute MI who underwent intravascular ultrasound (IVUS) evaluation of the infarct-related lesion before coronary intervention. All study patients were divided into two groups based on whether they presented with OHCA. The underlying mechanisms of acute MI were classified into four categories according to pre-interventional angiographic and IVUS images: plaque rupture, plaque erosion, calcified nodule, and embolization. Of the 604 patients diagnosed with acute MI, 69 (11%) suffered from OHCA. The OHCA group had a higher frequency of plaque rupture and calcified nodules than the non-OHCA group. Multivariate logistic regression analysis showed that an infarct-related lesion in the left main artery, the underlying plaque morphology of a calcified nodule, and plaque rupture were significantly associated with OHCA. In patients with acute MI, plaque morphology of infarct-related lesions with plaque rupture or a calcified nodule has a higher risk of leading to OHCA than other morphological types.","PeriodicalId":9439,"journal":{"name":"Cardiovascular Intervention and Therapeutics","volume":" ","pages":"788-795"},"PeriodicalIF":5.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144233283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Single catheter primary percutaneous coronary intervention method in patients with ST-elevation myocardial infarction: the SPEEDY-PCI study. st段抬高型心肌梗死患者单导管经皮冠状动脉介入治疗方法：speed - pci研究。

IF 5.8

Cardiovascular Intervention and Therapeutics Pub Date : 2025-10-01 Epub Date: 2025-07-07 DOI: 10.1007/s12928-025-01162-1

Sho Torii, Akihiko Takahashi, Yujiro Ono, Masanori Taniwaki, Mitsutoshi Oguri, Masanori Teramura, Ryuichi Kato, Shuji Otsuki, Hiroshi Suzuki, Fuminobu Yoshimachi, Hironori Ueda, Keisuke Shioji, Gaku Nakazawa, Kaoru Sakurai, Mitsuru Tsujimoto, Motosu Ando, Toshiyuki Kozai, Rie Aoyama, Yuji Ikari

{"title":"Single catheter primary percutaneous coronary intervention method in patients with ST-elevation myocardial infarction: the SPEEDY-PCI study.","authors":"Sho Torii, Akihiko Takahashi, Yujiro Ono, Masanori Taniwaki, Mitsutoshi Oguri, Masanori Teramura, Ryuichi Kato, Shuji Otsuki, Hiroshi Suzuki, Fuminobu Yoshimachi, Hironori Ueda, Keisuke Shioji, Gaku Nakazawa, Kaoru Sakurai, Mitsuru Tsujimoto, Motosu Ando, Toshiyuki Kozai, Rie Aoyama, Yuji Ikari","doi":"10.1007/s12928-025-01162-1","DOIUrl":"10.1007/s12928-025-01162-1","url":null,"abstract":"Reducing total ischemic time in ST-elevation myocardial infarction (STEMI) is crucial for improving outcomes. While procedural time during primary percutaneous coronary intervention (PCI) is critical, strategies to shorten it need to be explored. To examine whether the single-catheter PCI (SC-PCI) method using a universal guiding catheter, Ikari-Left curve, without catheter exchange reduces PCI time compared to conventional PCI (C-PCI). The Speedy PCI study is a prospective, multicenter, randomized trial comparing SC-PCI versus C-PCI. The primary endpoint was the time from sheath insertion to first device activation (S2B) time. Secondary endpoints included door-to-balloon time, total ischemia time, fluoroscopy time, contrast volume, hospital expenses, and 30-day mortality. A total of 380 patients (SC-PCI: 194; C-PCI: 186) were analyzed. Both groups had high primary PCI success rates (92.3 vs. 91.9%, p = 0.74) and similar radial access usage (higher than 97%). SC-PCI method showed a significantly shorter S2B time (15.8 ± 10.9 min) compared to the C-PCI method (18.7 ± 10.6 min, p = 0.007) with reduced number of total catheters used (1.2 ± 0.6 vs. 2.7 ± 0.7, p < 0.0001, respectively). No cases of coronary dissection caused by the guiding catheter were observed in the SC-PCI method. Clinical outcomes at 30 days and 1-year follow-up, including all-cause mortality and stroke rates, were similar between the groups. The SC-PCI method using the Ikari curve demonstrated a significant reduction in PCI procedure time while maintaining safety and primary PCI success in primary PCI for STEMI.","PeriodicalId":9439,"journal":{"name":"Cardiovascular Intervention and Therapeutics","volume":" ","pages":"807-819"},"PeriodicalIF":5.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12432066/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144583084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Short-term outcomes of transcatheter aortic valve implantation in patients with bicuspid aortic valve: insights from nationwide readmission analysis. 经导管主动脉瓣置入术治疗双尖瓣患者的短期疗效：来自全国再入院分析的见解。

IF 5.8

Cardiovascular Intervention and Therapeutics Pub Date : 2025-10-01 Epub Date: 2025-07-17 DOI: 10.1007/s12928-025-01173-y

Laith Alhuneafat, Fares Ghanem, Omar Obeidat, Anas Alzyoud, Abdel Latif Ma'aita, Mustafa Ajam, Ahmed M Altibi

{"title":"Short-term outcomes of transcatheter aortic valve implantation in patients with bicuspid aortic valve: insights from nationwide readmission analysis.","authors":"Laith Alhuneafat, Fares Ghanem, Omar Obeidat, Anas Alzyoud, Abdel Latif Ma'aita, Mustafa Ajam, Ahmed M Altibi","doi":"10.1007/s12928-025-01173-y","DOIUrl":"10.1007/s12928-025-01173-y","url":null,"abstract":"Transcatheter aortic valve implantation (TAVI) TAVI outcomes for patients with bicuspid aortic valve (BAV) and severe aortic stenosis are uncertain due to their exclusion from major clinical trials. We analyzed TAVI patients in the United States using data from the Nationwide Readmissions Database (2016-2019) identified using ICD-10 codes. We established matched cohorts of BAV and trileaflet aortic valve (TAV) patients using propensity-score matching (PSM). Primary outcomes were in-hospital mortality, 30-day mortality, and 30-day readmission rates. Out of 233,683 TAVI patients identified, 3169 (1.4%) had BAV. BAV patients were younger with fewer comorbidities. After PSM, 2,840 pairs were analyzed. Compared to TAV patients, TAVI in BAV patients showed comparable in-hospital mortality (1.2% vs. 2.0%; OR 0.62; 95% CI 0.36-1.04; p = 0.07) and 30-day readmission rates (10.0% vs. 12.3%; OR 0.79; 95% CI 0.60-1.03; p = 0.08), with lower 30-day mortality rates (0.88% vs. 1.96%; OR 0.44; 95% CI 0.23-0.84; p = 0.01). Post-TAVI in-hospital complications rates, including stroke, acute kidney injury, pacemaker need, and others, were similar between BAV and TAV patients. TAVI in BAV shows acceptable safety compared to TAV, but further randomized trials are needed to establish long-term outcomes and durability.","PeriodicalId":9439,"journal":{"name":"Cardiovascular Intervention and Therapeutics","volume":" ","pages":"921-931"},"PeriodicalIF":5.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144658433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Improvement in residual paravalvular leakage after transcatheter aortic valve replacement with a self-expanding valve: ACURATE neo2 versus ACURATE neo. 经导管主动脉瓣置换术后瓣旁残留渗漏的改善：accurate neo2 vs . accurate neo

IF 5.8

Cardiovascular Intervention and Therapeutics Pub Date : 2025-10-01 Epub Date: 2025-07-20 DOI: 10.1007/s12928-025-01170-1

Yoichi Sugiyama, Hirokazu Miyashita, Sebastian Dahlbacka, Tommi Vähäsilta, Tiina Vainikka, Mikko Jalanko, Juho Viikilä, Mika Laine, Noriaki Moriyama

{"title":"Improvement in residual paravalvular leakage after transcatheter aortic valve replacement with a self-expanding valve: ACURATE neo2 versus ACURATE neo.","authors":"Yoichi Sugiyama, Hirokazu Miyashita, Sebastian Dahlbacka, Tommi Vähäsilta, Tiina Vainikka, Mikko Jalanko, Juho Viikilä, Mika Laine, Noriaki Moriyama","doi":"10.1007/s12928-025-01170-1","DOIUrl":"10.1007/s12928-025-01170-1","url":null,"abstract":"The paravalvular leakage (PVL) incidence immediately after transcatheter aortic valve replacement (TAVR) is reportedly lower with ACURATE neo2 than with ACURATE neo. However, the difference in the subsequent PVL improvement between these valves and the improvement mechanism remain unclear. This study aimed to compare the incidence of and changes in the PVL between these valves and investigate the factors associated with PVL improvement. We included 403 patients who underwent TAVR with ACURATE neo2 (n = 134) or ACURATE neo (n = 269). The study endpoint was PVL improvement, defined as a reduction in the PVL grade from mild or higher at discharge to none/trace at 3 months. The PVL incidence of mild grade or higher was significantly lower with ACURATE neo2 than with ACURATE neo at 3 months (15.7% vs. 25.7%; p = 0.0234) but did not differ significantly at discharge (33.3% vs. 27.5%; p = 0.2291). A significant decrease in the PVL was observed only with ACURATE neo2 (p < 0.0001). Multivariate analysis demonstrated that ACURATE neo2 and calcium volume of the aortic leaflets were independent predictors of PVL improvement. The incidence of mild grade or higher PVL was lower with ACURATE neo2 than with ACURATE neo at 3 months due to the subsequent improvement. Patient selection focusing on leaflet calcification is important for preventing PVL because severe calcification impedes PVL improvement.","PeriodicalId":9439,"journal":{"name":"Cardiovascular Intervention and Therapeutics","volume":" ","pages":"909-920"},"PeriodicalIF":5.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12431930/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144667233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of the incidence of slow flow following rotational atherectomy to severely calcified coronary artery lesions between short single session and long single session strategies: the randomized ROTASOLO trial. 旋转动脉粥样硬化切除术治疗严重钙化冠状动脉病变后慢血流发生率的短期单次和长期单次策略的比较：随机ROTASOLO试验

IF 5.8

Cardiovascular Intervention and Therapeutics Pub Date : 2025-10-01 Epub Date: 2025-07-23 DOI: 10.1007/s12928-025-01177-8

Kenichi Sakakura, Hiroyuki Jinnouchi, Yousuke Taniguchi, Kei Yamamoto, Yoshimasa Tsurumaki, Takunori Tsukui, Yusuke Watanabe, Takaaki Mase, Masaru Seguchi, Taku Kasahara, Masashi Hatori, Shun Ishibashi, Hiroshi Wada, Yusuke Tamanaha, Kenshiro Arao, Norifumi Kubo, Hideo Fujita

{"title":"Comparison of the incidence of slow flow following rotational atherectomy to severely calcified coronary artery lesions between short single session and long single session strategies: the randomized ROTASOLO trial.","authors":"Kenichi Sakakura, Hiroyuki Jinnouchi, Yousuke Taniguchi, Kei Yamamoto, Yoshimasa Tsurumaki, Takunori Tsukui, Yusuke Watanabe, Takaaki Mase, Masaru Seguchi, Taku Kasahara, Masashi Hatori, Shun Ishibashi, Hiroshi Wada, Yusuke Tamanaha, Kenshiro Arao, Norifumi Kubo, Hideo Fujita","doi":"10.1007/s12928-025-01177-8","DOIUrl":"10.1007/s12928-025-01177-8","url":null,"abstract":"Slow flow is the most common complication of rotational atherectomy (RA). Compared with long single sessions, short single sessions may reduce the incidence of slow flow just after RA. This study aimed to compare the incidence of slow flow just after RA between short single session and long single session strategies. This multicenter, 1:1 randomized clinical trial was conducted at 3 hospitals in Japan. The short single session strategy was defined as repeating short single sessions (up to 15 s) of RA, whereas the long single session strategy was defined as repeating long single sessions (20-30 s) until the burr crossed the target lesion. The primary outcome was slow flow just after RA, which was defined as [(initial TIMI-frame count before RA) × 1.1 minus (TIMI-frame count just after RA)] less than 0. During the study period, 266 patients were included in the final study population and were randomly assigned to the Short single session group (n = 132) or the long single session group (n = 134). The protocol adherence rate was equally high in both groups (Short single session: 98.5% versus long single session 94.8%, p = 0.172). The incidence of slow flow just after RA was similar between the 2 groups (short single session:14.4% versus long single session: 14.9%, p > 0.999). In conclusion, this randomized trial did not show a benefit of the short single session strategy compared with the long single session strategy in RA with respect to the prevention of slow flow (Unique identifier: UMIN000047231).","PeriodicalId":9439,"journal":{"name":"Cardiovascular Intervention and Therapeutics","volume":" ","pages":"827-839"},"PeriodicalIF":5.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12432047/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144688938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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