Cardiovascular Intervention and Therapeutics最新文献

Optimal endovascular strategy for femoropopliteal claudication and infrapopliteal CLTI: a network meta-analysis stratified by lesion length. 股腘窝跛行和股腘窝下CLTI的最佳血管内策略：一项按病变长度分层的网络荟萃分析。

IF 5.8

Cardiovascular Intervention and Therapeutics Pub Date : 2025-10-19 DOI: 10.1007/s12928-025-01208-4

Yang Zhou, Chang Shu, Zhihui Zhang, Tun Wang, Hao He, Quanming Li

{"title":"Optimal endovascular strategy for femoropopliteal claudication and infrapopliteal CLTI: a network meta-analysis stratified by lesion length.","authors":"Yang Zhou, Chang Shu, Zhihui Zhang, Tun Wang, Hao He, Quanming Li","doi":"10.1007/s12928-025-01208-4","DOIUrl":"https://doi.org/10.1007/s12928-025-01208-4","url":null,"abstract":"While numerous endovascular technologies exist for lower extremity arterial disease (LEAD), evidence guiding device selection based on lesion length is limited. We therefore conducted a network meta-analysis to compare the efficacy of contemporary endovascular therapy (EVT) strategies, stratified by clinical presentation and lesion length. Following PRISMA guidelines (PROSPERO: CRD420251031338), we searched major databases for randomized controlled trials (RCTs) comparing nine contemporary endovascular therapy (EVT) modalities for femoropopliteal intermittent claudication (IC) or infrapopliteal chronic limb-threatening ischemia (CLTI). Analyses were stratified by lesion length (short vs. long) for each clinical subgroup. Primary outcomes were primary patency, target lesion revascularization (TLR), major amputation and all-cause mortality at multiple follow-up intervals. Seventy seven RCTs involving 11,788 patients were included. For short femoropopliteal IC lesions (≤ 73.0 mm), drug-coated balloon (DCB) and covered stent were most effective for maintaining patency. For long femoropopliteal lesions (> 73.0 mm), atherectomy with DCB (AT-DCB) and drug-eluting stent (DES) demonstrated superior patency. In short infrapopliteal CLTI lesions (≤ 44.1 mm), DES provided the most consistent benefits in both patency and freedom from TLR. For long infrapopliteal lesions (> 44.1 mm), AT-DCB was the most effective strategy for improving primary patency. Importantly, no significant differences in major amputation or mortality were detected among strategies in most subgroups. The optimal endovascular strategy for LEAD appears to be highly dependent on lesion length, supporting a shift towards a more individualized treatment strategy.","PeriodicalId":9439,"journal":{"name":"Cardiovascular Intervention and Therapeutics","volume":" ","pages":""},"PeriodicalIF":5.8,"publicationDate":"2025-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145318133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A pivotal study on the novel cutting balloon KCB01 in patients with coronary artery disease. 新型切割球囊KCB01在冠心病患者中的关键性研究

IF 5.8

Cardiovascular Intervention and Therapeutics Pub Date : 2025-10-17 DOI: 10.1007/s12928-025-01205-7

Yoshisato Shibata, Yoshiaki Ito, Shigeru Nakamura, Koichi Kishi, Yuji Oikawa, Takashi Muramatsu, Gaku Nakazawa, Hisashi Koga, Kenichi Sakakura, Takuya Shida, Masato Nakamura

{"title":"A pivotal study on the novel cutting balloon KCB01 in patients with coronary artery disease.","authors":"Yoshisato Shibata, Yoshiaki Ito, Shigeru Nakamura, Koichi Kishi, Yuji Oikawa, Takashi Muramatsu, Gaku Nakazawa, Hisashi Koga, Kenichi Sakakura, Takuya Shida, Masato Nakamura","doi":"10.1007/s12928-025-01205-7","DOIUrl":"https://doi.org/10.1007/s12928-025-01205-7","url":null,"abstract":"The KCB01 (KIZASHI™) is a novel cutting balloon catheter with blades integrally formed with the balloon. It is designed to overcome the drawbacks of conventional cutting balloons in terms of lesion delivery, crossability and procedural complications while maintaining the same dilation capacity. To evaluate the efficacy and safety of the KCB01, a prospective, open-label, single-arm study was conducted at nine sites in Japan on percutaneous coronary intervention-eligible patients with stenotic lesions that exhibited residual indentation even after conventional balloon dilation at nominal pressure. Seventy-six patients were enrolled between November 2022 and June 2023, and 73 eligible patients were included in the primary analysis. The mean age was 73.5 ± 7.4 years, and 79.5% of the patients were male. The target lesion characteristics included bifurcation lesions (42.5%), in-stent restenosis lesions (20.5%), and severely calcified lesions (54.8%). The primary endpoint was procedural success, defined as the KCB01 crossing the target lesion, no residual indentation, and < 50% residual stenosis rate after KCB01 dilation (assessed using quantitative coronary angiography). The angiographic images obtained during the procedure were evaluated in a core laboratory. The procedural success rate was 87.7% (95% confidence interval [CI]: 77.9-94.2), with the lower limit of the 95% CI (77.9%) exceeding the performance goal of 76.5%. Clinical success rate was achieved in 94.5% of cases (95% CI: 86.6-98.5%), with no major adverse cardiac events reported until discharge. Furthermore, no device deficiencies related to the KCB01 were observed. These results suggest the safety and efficacy of the KCB01.","PeriodicalId":9439,"journal":{"name":"Cardiovascular Intervention and Therapeutics","volume":" ","pages":""},"PeriodicalIF":5.8,"publicationDate":"2025-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145306922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Large stent frame deformation in a self-expandable transcatheter heart valve after valve-in-valve implantation for failed surgical valve. 自膨胀经导管心脏瓣膜置入术中瓣膜植入失败后支架框架大变形。

IF 5.8

Cardiovascular Intervention and Therapeutics Pub Date : 2025-10-14 DOI: 10.1007/s12928-025-01206-6

Tetsuro Shimura, Masanori Yamamoto, Kakeru Ishihara, Yusuke Okubo, Hirooki Higami, Hitoshi Matsuo

引用次数: 0

Guide extension catheters in coronary intervention: device selection, technical insights, and clinical applications. 冠状动脉介入治疗中的导管延伸：设备选择、技术见解和临床应用。

IF 5.8

Cardiovascular Intervention and Therapeutics Pub Date : 2025-10-12 DOI: 10.1007/s12928-025-01207-5

Yoshiyasu Minami, Takayuki Warisawa, Aritomo Katsura, Takuma Tsuda, Kenichi Hagiya, Koki Shishido, Takuya Hashimoto, Takashi Ashikaga

{"title":"Guide extension catheters in coronary intervention: device selection, technical insights, and clinical applications.","authors":"Yoshiyasu Minami, Takayuki Warisawa, Aritomo Katsura, Takuma Tsuda, Kenichi Hagiya, Koki Shishido, Takuya Hashimoto, Takashi Ashikaga","doi":"10.1007/s12928-025-01207-5","DOIUrl":"https://doi.org/10.1007/s12928-025-01207-5","url":null,"abstract":"Percutaneous coronary intervention (PCI) has evolved significantly with technological advances, allowing for higher procedural success rates and improved patient outcomes. However, the growing complexity of cases involving severely calcified lesions, tortuous vessels, and chronic total occlusions has increased procedural challenges. In such scenarios, the guide extension catheter (GEC, or guiding catheter extension) plays a critical role by enhancing device passage and providing additional backup support, making it indispensable in modern PCI. Various types of GECs offer distinct characteristics that influence their selection based on lesion type, device compatibility, and procedural requirements. The GEC is used for multiple purposes, including backup support, deep engagement, imaging device insertion, stent protection, thrombectomy, and foreign body removal. Despite its utility, GEC use is associated with potential complications, including vessel injury, thrombosis, air embolism, and hemodynamic instability. Careful technique and proper selection are critical to minimizing risks. Overall, the GEC is an essential tool in complex PCI procedures, offering significant advantages in improving procedural success.","PeriodicalId":9439,"journal":{"name":"Cardiovascular Intervention and Therapeutics","volume":" ","pages":""},"PeriodicalIF":5.8,"publicationDate":"2025-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145279014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of coronary calcium patterns on procedural outcomes in CTO-PCI: a computed tomography-based multicenter study. 冠状动脉钙形态对CTO-PCI手术结果的影响：一项基于计算机断层扫描的多中心研究。

IF 5.8

Cardiovascular Intervention and Therapeutics Pub Date : 2025-10-11 DOI: 10.1007/s12928-025-01200-y

Giuseppe Panuccio, Gerald S Werner, Salvatore De Rosa, Daniele Torella, Yasuhiro Ichibori, Nicole Carabetta, Carsten Skurk, Patrick T Siegrist, David M Leistner, Ömer Göktekin, Kambis Mashayekhi, Ulf Landmesser, Youssef S Abdelwahed

{"title":"Impact of coronary calcium patterns on procedural outcomes in CTO-PCI: a computed tomography-based multicenter study.","authors":"Giuseppe Panuccio, Gerald S Werner, Salvatore De Rosa, Daniele Torella, Yasuhiro Ichibori, Nicole Carabetta, Carsten Skurk, Patrick T Siegrist, David M Leistner, Ömer Göktekin, Kambis Mashayekhi, Ulf Landmesser, Youssef S Abdelwahed","doi":"10.1007/s12928-025-01200-y","DOIUrl":"https://doi.org/10.1007/s12928-025-01200-y","url":null,"abstract":"Coronary calcium significantly increases complexity in chronic total occlusion percutaneous coronary intervention (CTO-PCI). Coronary computed tomography angiography (CCTA) enables precise CTO assessment. However, no prior study has proposed a CCTA-based morphological classification of calcium patterns and assessed its procedural impact. To propose and validate a novel seven-point CCTA-derived classification of calcium morphology, ranging from \"spot\" (≤ 10% cross-sectional area, CSA) to \"full moon\" (100% CSA). We retrospectively included 167 patients undergoing CTO-PCI with prior CCTA. The primary endpoint was procedural failure. Secondary endpoints included coronary perforations, procedural and fluoroscopic time, and number of guidewires and balloons. A progressive, stepwise increase in procedural failure (from 6.2% in spot to 26.7% in full moon lesions; p = 0.007) and coronary perforation rates (from 3.1% in spot to 13.3% in full moon lesions; p = 0.03) was observed across the seven identified calcium patterns. In multivariable analysis, calcium severity was independently associated with procedural failure (OR 1.2 per step; 95% CI 1.01-1.52; p = 0.04). Increasing calcium severity was also independently associated with procedural time (B = + 4.7 min/step; p = 0.03), fluoroscopic time (B = + 2.2 min/step; p = 0.04), number of guidewires (B = + 0.30/step; p = 0.03) and balloons (B = + 0.31/step; p = 0.005). Full-scale progression from \"spot\" to \"full moon\" corresponded to + 33 min increase in procedural and + 14 min in fluoroscopic time. A novel CCTA-based calcium classification showed a strong, independent association with procedural failure and complexity. Its reproducibility and integration potential make it a valuable tool for enhancing planning and safety in CTO-PCI.","PeriodicalId":9439,"journal":{"name":"Cardiovascular Intervention and Therapeutics","volume":" ","pages":""},"PeriodicalIF":5.8,"publicationDate":"2025-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145273883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fusion imaging-guided closure of spontaneous sinus of Valsalva aneurysm rupture. 融合成像引导下自发性血管瘤破裂窦闭合。

IF 5.8

Cardiovascular Intervention and Therapeutics Pub Date : 2025-10-01 Epub Date: 2025-05-27 DOI: 10.1007/s12928-025-01142-5

Juan P Sandoval, Eduardo A Arias-Sanchez, José A Arias-Godínez, Veronica C Rodriguez-Esparza, Axel A Rodriguez-Mendez, Hugo Rodriguez-Zanella

引用次数: 0

Enhancement of posterior mitral leaflet imaging quality during the MitraClip procedure using one-lung ventilation. 在单肺通气的MitraClip手术中增强二尖瓣后小叶成像质量。

IF 5.8

Cardiovascular Intervention and Therapeutics Pub Date : 2025-10-01 Epub Date: 2025-05-17 DOI: 10.1007/s12928-025-01138-1

Masafumi Sato, Kenji Harada, Koichi Yoshinaga, Koichiro Seki, Koji Kawahito, Kazuomi Kario

引用次数: 0

Iatrogenic laceration of the atrial septum during catheter ablation for atrial fibrillation in a patient with multiple atrial septal defects. 多重房间隔缺损患者房颤导管消融过程中房间隔的医源性撕裂。

IF 5.8

Cardiovascular Intervention and Therapeutics Pub Date : 2025-10-01 Epub Date: 2025-06-24 DOI: 10.1007/s12928-025-01163-0

Koji Nakagawa, Yoichi Takaya, Teiji Akagi, Takashi Miki, Hiroshi Morita, Shinsuke Yuasa

引用次数: 0

Optimal result with PASCAL device for recurrent mitral regurgitation after surgical mitral valve repair. 应用PASCAL装置治疗二尖瓣修复术后复发性二尖瓣返流的最佳效果。

IF 5.8

Cardiovascular Intervention and Therapeutics Pub Date : 2025-10-01 Epub Date: 2025-06-28 DOI: 10.1007/s12928-025-01165-y

Hiroaki Yokoyama, Tatsuya Kokawa, Tomoko Izumi, Shinobu Hosokawa

引用次数: 0

In-stent restenosis caused by late-protruding native atherosclerosis through uncovered struts: observations with coronary angioscopy. 晚期突出的原生动脉粥样硬化通过未覆盖支架引起支架内再狭窄：冠状动脉镜观察。

IF 5.8

Cardiovascular Intervention and Therapeutics Pub Date : 2025-10-01 Epub Date: 2025-07-04 DOI: 10.1007/s12928-025-01166-x

Tsukasa Murakami, Keisuke Kojima, Hiroyuki Jinnouchi, Masanori Takenoya

引用次数: 0