Cardiovascular Intervention and Therapeutics最新文献

{"title":"Plaque rupture and calcified nodules: major contributors to out-of-hospital cardiac arrest in acute myocardial infarction.","authors":"Takato Hirose, Kenichi Fujii, Kenta Hashimoto, Kazunori Bando, Shun Morishita, Masanao Taniichi, Keita Horitani, Ichiro Shiojima","doi":"10.1007/s12928-025-01146-1","DOIUrl":"https://doi.org/10.1007/s12928-025-01146-1","url":null,"abstract":"<p><p>Since patients with cardiac arrest associated with acute myocardial infarction (MI) may not be successfully resuscitated, the underlying mechanisms of acute MI leading to out-of-hospital cardiac arrest (OHCA) have not been elucidated. This study evaluated whether there are differences in the plaque characteristics of infarct-related lesions between acute MI patients with OHCA and those without OHCA. This study analyzed 604 consecutive patients with a diagnosis of acute MI who underwent intravascular ultrasound (IVUS) evaluation of the infarct-related lesion before coronary intervention. All study patients were divided into two groups based on whether they presented with OHCA. The underlying mechanisms of acute MI were classified into four categories according to pre-interventional angiographic and IVUS images: plaque rupture, plaque erosion, calcified nodule, and embolization. Of the 604 patients diagnosed with acute MI, 69 (11%) suffered from OHCA. The OHCA group had a higher frequency of plaque rupture and calcified nodules than the non-OHCA group. Multivariate logistic regression analysis showed that an infarct-related lesion in the left main artery, the underlying plaque morphology of a calcified nodule, and plaque rupture were significantly associated with OHCA. In patients with acute MI, plaque morphology of infarct-related lesions with plaque rupture or a calcified nodule has a higher risk of leading to OHCA than other morphological types.</p>","PeriodicalId":9439,"journal":{"name":"Cardiovascular Intervention and Therapeutics","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144233283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impella insertion through fenestrated thoracic stent graft.","authors":"Masataka Hirota, Yuki Ichihara, Takashi Azuma, Satoru Domoto, Hiroshi Niinami","doi":"10.1007/s12928-025-01149-y","DOIUrl":"https://doi.org/10.1007/s12928-025-01149-y","url":null,"abstract":"","PeriodicalId":9439,"journal":{"name":"Cardiovascular Intervention and Therapeutics","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144233282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of transcatheter patent foramen ovale closure for drug-resistant migraine: initial experience in Japan and long-term outcome.","authors":"Teiji Akagi, Yoichi Takaya, Takashi Miki, Rie Nakayama, Koji Nakagawa, Mitsuki Nakashima, Yoshiaki Takahashi, Nozomi Hishikawa, Shinsuke Yuasa","doi":"10.1007/s12928-025-01135-4","DOIUrl":"https://doi.org/10.1007/s12928-025-01135-4","url":null,"abstract":"<p><p>This study evaluates the efficacy and safety of transcatheter patent foramen ovale (PFO) closure for the treatment of drug-resistant migraine in Japan. Previous studies have suggested a potential benefit for migraine with aura, although large-scale trials in the United States and Europe have failed to confirm efficacy as a primary endpoint. The study included 27 patients (mean age 36.4 years, 15 female, 21 with aura) who had more than two migraine attacks per month despite medication. All had PFO confirmed by transesophageal echocardiography and underwent transcatheter closure with the Amplatzer PFO Occluder. Patients were followed up to 12 months with migraine severity monitored by headache specialist. The procedure was successful and without complications in all cases. One patient required a larger occluder (35 mm) due to the size of PFO. At 12 months, 22 of 27 (81%) patients reported either complete resolution or improvement of migraine. Specifically, 10 of 21 (48%) patients with aura experienced complete resolution of migraine at one year. Patients without aura had a lower response rate, with only one case of complete resolution. Despite limitations such as the lack of a control group and potential patient selection bias, the study demonstrated that PFO closure may provide significant relief for patients with drug-resistant migraine, particularly those with aura. These findings support further investigation to better define its clinical indications and potential benefits.</p>","PeriodicalId":9439,"journal":{"name":"Cardiovascular Intervention and Therapeutics","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144215005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison between robot-assisted and manual percutaneous coronary intervention - an updated systematic review, meta-analysis, propensity-matched investigation, and trial sequential analysis.","authors":"Paweł Łajczak, Ayesha Ayesha, Oguz Kagan Sahin, Priscilla Isabel Freeman, Mir Wajid Majeed, Bruno Branco Righetto, Ogechukwu Obi, Gabriel Jacob Moreno, Mrinal Murali Krishna, Kangwa Francis Mulenga, Emma Ann Finnegan, Meghna Joseph, Anna Łajczak, Michele Schincariol","doi":"10.1007/s12928-025-01131-8","DOIUrl":"https://doi.org/10.1007/s12928-025-01131-8","url":null,"abstract":"<p><p>Robotic-assistance in the percutaneous coronary intervention procedures (R-PCI) has emerged as a novel alternative to manual PCI (M-PCI). However, previous reviews have not incorporated advancements in new devices. Therefore, we aim to present updated results for a comprehensive systematic review and meta-analysis comparing these two modalities.We systematically searched five databases. Clinical studies comparing R-PCI to M-PCI were included. Continuous outcomes were analyzed using a mean difference (MD), while binary outcomes were assessed with odds ratios (ORs) using random-effect models due to anticipated heterogeneity. A total of 10 papers were included. Clinical success for < 20% residual stenosis was higher (OR 7.93 (95% CI 1.02 to 61.68)), while air kerma was lower (MD - 468.61 (95% CI - 718.32 to - 218.90)) in R-PCI procedures. However, procedural time (MD 5.57 (95% CI - 5.69 to 16.84)), fluoroscopy time (MD - 0.30 (95% CI - 2.26 to 1.66)), contrast dose (MD - 6.29 (95% CI - 25.23 to 12.65)), dose area product (MD - 642.57 (95% CI - 2434.20 to 1149.07)), MACE events (OR 0.54 (95% CI 0.15 to 1.96)), and mortality (OR 1.86 (95% CI 0.82 to 4.22)) showed no significant difference between interventions. TSA showed true positive result. Our meta-analysis reveals decreased air kerma in robotic versus manual PCI but fewer statistically significant outcomes overall. Results from this study offer a more comprehensive view of existing evidence compared to previous analyses.</p>","PeriodicalId":9439,"journal":{"name":"Cardiovascular Intervention and Therapeutics","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144186564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility of optical coherence tomography-guided primary percutaneous coronary intervention for STEMI: all-comer ATLAS-OCT trial.","authors":"Kohei Wakabayashi, Taishi Yonetsu, Takuya Mizukami, Myong Hwa Yamamoto, Sakiko Yasuhara, Koki Shishido, Shigeru Saito, Nobuaki Kobayashi, Masamichi Takano, Eisuke Usui, Tsunekazu Kakuta, Yosuke Oishi, Seita Kondo, Tenjin Nishikura, Yoshiyasu Minami, Junya Ako, Toshitaka Okabe, Toru Naganuma, Satoru Mitomo, Sunao Nakamura, Takumi Higuma, Junya Shite, Amane Kozuki, Satoru Suwa, Teruyoshi Kume, Shiro Uemura, Genki Naruse, Hiroyuki Okura, Yosuke Yamakami, Hiroyuki Fujii, Shigeki Kimura, Masamichi Iwasaki, Makoto Araki, Tomoyo Sugiyama, Mamoru Nanasato, Tomotaka Dohi, Takashi Ashikaga, Hiroyoshi Mori, Teruo Sekimoto, Yoichiro Sugizaki, Hiromasa Otake, Toshiro Shinke","doi":"10.1007/s12928-025-01137-2","DOIUrl":"https://doi.org/10.1007/s12928-025-01137-2","url":null,"abstract":"<p><p>Intravascular imaging for acute coronary syndrome is recommended in the guidelines; however, the actual rate of patients with ST-segment elevation myocardial infarction (STEMI) who successfully undergo optical coherence tomography (OCT)-guided primary percutaneous coronary intervention (PCI) is unclear. This study aimed to determine the feasibility of OCT-guided primary PCI and identify the patient population that would benefit most from OCT guidance in STEMI. The ATLAS-OCT trial was a prospective, single-arm, all-comers study conducted at 16 institutions. The primary endpoint was the feasibility of OCT guidance for primary PCI, defined as successful image acquisition (vessel's circumferential or > 270° visualization along > 70% of the lesion's length, as evaluated by an independent core laboratory). A total of 632 patients (mean age: 68.4 years; 80.2% male) were enrolled in the study. OCT-guided PCI was performed in 503 patients, whereas OCT guidance was avoided in 129 patients for patient's condition. Successful image acquisition was achieved in all but seven patients who underwent OCT. The primary endpoint was achieved in 78.5% (496/632) of patients. No procedural complications were associated with OCT. Patients with left main disease (adjusted odds ratio, 4.1; 95% confidence interval, 1.2-14.7; p = 0.024), estimated glomerular filtration rate (mL/min/1.73 m²) < 30 (3.7; 1.6-8.3; p = 0.002), and Killip IV (2.5; 1.3-4.6; p = 0.003) were significantly avoided for OCT guidance. OCT guidance was feasible in four-fifths of all-comers with STEMI. Further studies are warranted to evaluate the efficacy of OCT-guided PCI in selected patient populations based on the findings of this trial (UMIN000048590).</p>","PeriodicalId":9439,"journal":{"name":"Cardiovascular Intervention and Therapeutics","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144186565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fusion imaging-guided closure of spontaneous sinus of Valsalva aneurysm rupture.","authors":"Juan P Sandoval, Eduardo A Arias-Sanchez, José A Arias-Godínez, Veronica C Rodriguez-Esparza, Axel A Rodriguez-Mendez, Hugo Rodriguez-Zanella","doi":"10.1007/s12928-025-01142-5","DOIUrl":"https://doi.org/10.1007/s12928-025-01142-5","url":null,"abstract":"","PeriodicalId":9439,"journal":{"name":"Cardiovascular Intervention and Therapeutics","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144157011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprehensive analysis of acute kidney injury incidence following transcatheter versus surgical aortic valve replacement in aortic stenosis: a systematic review and meta-analysis of 13,777 patients.","authors":"Ahmad Alazzam, Yacoub Aldroubi, Tariq Alhusban, Mosab Said","doi":"10.1007/s12928-025-01144-3","DOIUrl":"https://doi.org/10.1007/s12928-025-01144-3","url":null,"abstract":"<p><p>This systematic review and meta-analysis evaluate Acute Kidney Injury (AKI) differences between surgical aortic valve replacement (SAVR) and transcatheter aortic valve replacement (TAVR) and how surgical risk stratification and diagnostic criteria influence outcomes. Following the PRISMA guidelines, we included both non-randomized studies and randomized clinical trials that reported AKI criteria and patients' surgical risk in patients with aortic stenosis by searching PubMed, Scopus, and Web of Science until late September. We executed a random-effects model in Review Manager to pool effect estimates of AKI incidence or the need for dialysis as an odds ratio (OR) and I² heterogeneity, and we utilized R for meta-regression to address any heterogeneity with subgroup analysis for surgical risk, AKI criteria, and study design. We used the Newcastle Ottawa Scale (NOS) and the Cochrane Risk of Bias Tool (RoB-1) for risk of bias assessment and GRADE for certainty assessment. Involving 17 studies and a total of 13,777 patients, we found that the AKI incidence was significantly lower in TAVR compared to SAVR (OR = 0.36; 95% CI: [0.30, 0.44], I² = 55%, P = 0.003), along with the need for dialysis (OR = 0.35; 95% CI: [0.19, 0.63], I² = 0%, P = 0.92). The study also found that intermediate and low-risk patients had more favorable outcomes. However, the retrospective study design and VARC-2 criteria were associated with unfavorable outcomes. TAVR effectively reduced the risk of AKI in all surgical risk categories and the need for dialysis compared to SAVR in patients with AS.</p>","PeriodicalId":9439,"journal":{"name":"Cardiovascular Intervention and Therapeutics","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144148943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between psoas muscle area and outcomes after transcatheter tricuspid valve repair.","authors":"Mahmoud Balata, Tetsu Tanaka, Atsushi Sugiura, Refik Kavsur, Johanna Vogelhuber, Can Öztürk, Sebastian Zimmer, Julian Luetkens, Georg Nickenig, Marcel Weber","doi":"10.1007/s12928-025-01136-3","DOIUrl":"https://doi.org/10.1007/s12928-025-01136-3","url":null,"abstract":"<p><p>Transcatheter tricuspid valve repair (TTVR) might be an alternative option to reduce tricuspid regurgitation (TR) in patients with sarcopenia. Psoas muscle area (PMA) measured using computed tomography (CT) is known as a marker of sarcopenia. We investigated the association of PMA with procedural and clinical outcomes following TTVR. We retrospectively measured left and right PMA using pre-procedural CT in patients undergoing TTVR. Low PMA was defined as the total PMA < 20.3 cm² for men and < 11.8 cm² for women. The primary outcome was a composite of all-cause mortality and heart failure hospitalization within one year after TTVR. Of 163 patients, 47 (29%) were considered as having low PMA. Procedural success, defined as residual TR of ≤ 2 + at discharge, and in-hospital mortality were comparable between patients with low and high PMA. Patients with low PMA had a higher incidence of the composite outcome than those with high PMA (49% vs. 21%; p = 0.001) This association was consistent after adjusting for baseline characteristics (adjusted hazard ratio 0.43; 95% confidence interval: 0.23-0.80; p = 0.008). In contrast, the New York Heart Association functional class improved from baseline to three-month follow-up, regardless of PMA. Approximately 30% of patients undergoing TTVR were found to have low PMA. Although TTVR may be a safe therapeutic option to reduce TR and improve heart failure symptoms in patients with sarcopenia, the prognosis after TTVR remains poor in this population. Pre-procedural CT-based assessment of PMA may enhance risk stratification and support better clinical decision-making for TTVR.</p>","PeriodicalId":9439,"journal":{"name":"Cardiovascular Intervention and Therapeutics","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144149598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation between coronary angioscopy yellow grade and lipid plaque assessment by integrated backscatter intravascular ultrasound.","authors":"Atsushi Tanita, Shinichiro Sunamura, Tsuyoshi Ogata, Kazuki Noda, Toru Takii, Yoshio Nitta, Seijiro Yoshida, Shigeto Namiuchi","doi":"10.1007/s12928-025-01133-6","DOIUrl":"https://doi.org/10.1007/s12928-025-01133-6","url":null,"abstract":"<p><p>Coronary angioscopy (CAS) enables direct qualitative assessment of the coronary artery lumen, while integrated backscatter intravascular ultrasound (IB-IVUS) provides a quantitative evaluation of coronary plaque tissue characteristics. Despite the utility of both techniques in assessing coronary plaque status, data on the correlation between their findings remain limited. To investigate the association between CAS-derived findings and results obtained through IB-IVUS. This retrospective analysis included 36 patients who underwent both CAS and IB-IVUS during percutaneous coronary intervention (PCI) at our institution. CAS and IB-IVUS were performed on the same coronary artery treated during PCI. Plaques were categorized into four groups based on their yellow color grade using CAS. For the IB-IVUS analysis, measurements were performed at the minimum lumen diameter site of the culprit lesion. A significant correlation was observed between plaque yellowishness and plaque characteristics on IB-IVUS. Higher plaque yellowishness was associated with an increased percentage of all lipid pool (P < 0.01), a greater proportion of attenuated plaque (P < 0.01), and a larger estimated lipid plaque volume (P < 0.01). Additionally, plaques with higher yellowishness grades had significantly thinner fibrous caps (P < 0.01). The findings suggest that higher plaque yellowishness observed via CAS correlates with a larger lipid plaque volume and thinner fibrous caps, as assessed through IB-IVUS.</p>","PeriodicalId":9439,"journal":{"name":"Cardiovascular Intervention and Therapeutics","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144149119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparable clinical characteristics and outcomes of patients undergoing endovascular treatment for aorto-iliac or femoropopliteal lesions.","authors":"Yuichi Saito, Yuji Ohno, Kayo Yamamoto, Norikiyo Oka, Masayuki Takahara, Sakuramaru Suzuki, Raita Uchiyama, Masahiro Suzuki, Tadahiro Matsumoto, Yo Iwata, Hideki Kitahara, Yoshio Kobayashi","doi":"10.1007/s12928-025-01143-4","DOIUrl":"https://doi.org/10.1007/s12928-025-01143-4","url":null,"abstract":"<p><p>Lower extremity peripheral arterial disease is usually a consequence of advanced atherosclerosis, leading to high mortality and morbidity. Although clinical characteristics and outcomes may differ among patients having peripheral disease in different arterial territories, contemporary data are scarce. From January 2019 to December 2022, this multicenter registry study included 712 patients undergoing endovascular treatment (EVT) for either aorto-iliac (AI) or femoropopliteal (FP) lesions. Patient characteristics and outcomes were compared between AI-EVT and FP-EVT groups. Clinical endpoints included major adverse cardiovascular events, major adverse limb events (MALE), and all-cause mortality, stratified by chronic limb-threatening ischemia (CLTI). Of the 712 patients, 217 (30.5%) and 495 (69.5%) underwent AI-EVT or FP-EVT. Patients undergoing AI-EVT were more likely to be men and current smokers, while diabetes was more frequent in the FP-EVT group. The prevalence of CLTI was significantly higher in the FP-EVT group. In the entire study population, the FP-EVT rather than the AI-EVT group had a significantly higher rate of MALE and mortality, but the incidence of major adverse cardiovascular events was similar between the two groups. When focusing only on patients without CLTI, the mortality risk was similar, while the MALE risk was still higher in the FP-EVT group. In conclusion, patients undergoing EVT for AI and FP lesions in contemporary settings were differently characterized by baseline factors. Although the worse clinical outcomes in the FP-EVT group were mainly driven by the higher prevalence of CLTI, the MALE risk was still increased in patients without CLTI.</p>","PeriodicalId":9439,"journal":{"name":"Cardiovascular Intervention and Therapeutics","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144136010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}