Turkish neurosurgery最新文献

{"title":"Prediction and Analysis of Risk Factors for Lower Extremity Deep Vein Thrombosis After Craniotomy in Patients with Primary Brain Tumors: A Machine Learning Approach.","authors":"Lingzhi Wu, Yunfeng Zhao, Guangli Yao, Xiaojing Li, Xiaomin Zhao","doi":"10.5137/1019-5149.JTN.47938-24.3","DOIUrl":"10.5137/1019-5149.JTN.47938-24.3","url":null,"abstract":"<p><strong>Aim: </strong>To explore the risk factors associated with the occurrence of lower extremity deep vein thrombosis (DVT) after craniotomy in patients with primary brain tumors, and to develop a predictive model using machine learning.</p><p><strong>Material and methods: </strong>A prospective cohort study was conducted on 140 patients with primary brain tumors who underwent neurosurgical treatment at our hospital between March 2021 and September 2022. A logistic regression analysis was performed to identify independent risk factors associated with postoperative DVT. Additionally, multiple machine learning models were developed and evaluated to determine their predictive performance.</p><p><strong>Results: </strong>The incidence of lower extremity DVT after craniotomy was 27.9%. Logistic regression identified age [OR=1.07, 95% CI (1.03-1.11)], GCS score [OR=0.88, 95% CI (0.78-0.98)], D-dimer level [OR=1.08, 95% CI (1.02-1.15)], and mechanical ventilation (&ge;48 hours) [OR=3.83, 95% CI (1.21-12.15)] as independent risk factors (P < 0.05). The Gradient Boosting Machine (GBM) had the highest prediction accuracy among the assessed machine learning models, achieving an area under the curve (AUC) of 0.850, with a sensitivity of 56.44% and a specificity of 90.09%.</p><p><strong>Conclusion: </strong>Age, D-dimer, and mechanical ventilation (&ge;48 hours) are independent risk factors for the development of lower extremity DVT after craniotomy in patients with primary brain tumors. The GCS score serves as a potential protective risk factor. The GBM model, with its high AUC and specificity, offers a promising tool for early identification of high-risk patients, potentially informing clinical decision-making and targeted interventions.</p>","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":" ","pages":"636-643"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144513036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and Safety of Guideless Catheter Placement Technique in Revision External Ventricular Drainage and Ventricular Shunt Surgery.","authors":"Mustafa Umut Etli, Semra Isik, Ali Zinnar Kaya, Can Berkin Yaras, Cumhur Kaan Yaltirik, Hüseyin Sarikaya, Luay Serifoglu, Furkan Avci, Behrad Aras Nasehi, Ali Fatih Ramazanoglu","doi":"10.5137/1019-5149.JTN.46944-24.2","DOIUrl":"10.5137/1019-5149.JTN.46944-24.2","url":null,"abstract":"<p><strong>Aim: </strong>To evaluate the efficacy and safety of the guideless catheter placement technique in revision surgeries for external ventricular drainage (EVD) and ventricular shunt systems to improve treatment outcomes for hydrocephalus.</p><p><strong>Material and methods: </strong>We retrospectively analyzed 111 patients who underwent revision surgeries for EVD or ventricular shunt systems at the Istanbul Umraniye Training and Research Hospital from January 2020 to January 2023. Patients' demographic (age, sex), and clinical (cause of hydrocephalus, type of surgery, and postoperative complication rates, specifically for bleeding and catheter malposition) data were extracted from the patient files.</p><p><strong>Results: </strong>The use of the guideless catheter placement technique significantly reduced postoperative complications, with notably lower rates of bleeding (n=2, 1.8%) and catheter malposition (n=5, 4.5%).</p><p><strong>Conclusion: </strong>The guideless catheter placement technique is a viable, cost-effective, and efficient approach for revision surgeries in EVD and shunt systems, which can potentially improve the safety and accuracy of catheter placement, reduce complication rates, and ensure favorable patient outcomes associated with revision surgeries for hydrocephalus.</p>","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":" ","pages":"164-170"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142804178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Precision of Intraoperative Cone-Beam Computed Tomography in Electrode Placement and Complications in Asleep Deep Brain Stimulation Surgery: A Multidetector Computed Tomography-Verified Comparative Study.","authors":"Ali Haluk Duzkalir, Yavuz Samanci, Selcuk Peker","doi":"10.5137/1019-5149.JTN.47969-24.2","DOIUrl":"10.5137/1019-5149.JTN.47969-24.2","url":null,"abstract":"<p><strong>Aim: </strong>To examine intraoperative cone-beam computed tomography (iCBCT) accuracy, and the need for postoperative imaging to confirm electrode position, and to assess the complications of deep brain stimulation (DBS) surgery.</p><p><strong>Material and methods: </strong>Thirty-two movement disorder patients and 69 targets were retrospectively reviewed. All patients had preoperative non-stereotactic 3.0 Tesla magnetic resonance imaging (MRI), preoperative stereotactic multidetector computed tomography (MDCT), post-implantation iCBCT, and postoperative conventional MDCT scans. Stereotactic coordinates of electrode tips were compared between postoperative MDCT and iCBCT. We calculated the absolute and Euclidian differences (ED) between iCBCT and postoperative MDCT coordinates for each electrode. To assess whether intraoperative brain shifting influenced electrode tip localisation, subdural pneumocephalus volume was measured in iCBCT images.</p><p><strong>Results: </strong>The mean absolute (scalar) differences in x, y, and z coordinates were not significantly different from the absolute precision value of 0 (p > 0.05). The mean ED between the iCBCT electrode tip and the postoperative MDCT electrode tip coordinates was < 1mm (0.55±0.03 mm) and differed significantly from zero (p < 0.0001). There was no correlation between pneumocephalus volume and electrode coordinate deviation.</p><p><strong>Conclusion: </strong>iCBCT can eliminate the need for routine postoperative studies since it is a safe, effective, and rapid procedure that can be performed at any step of the surgery. It provides reliable and definitive confirmation of correct DBS electrode placement.</p>","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":" ","pages":"331-336"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143019248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Postoperative Prognosis on Carotid Endarterectomy: Single Center Experience.","authors":"Murat Zaimoglu, Baran Can Alpergin, Emre Bahir Mete, Ozgur Orhan, Omer Mert Ozpiskin, Melih Bozkurt, Umit Eroglu","doi":"10.5137/1019-5149.JTN.46537-24.2","DOIUrl":"10.5137/1019-5149.JTN.46537-24.2","url":null,"abstract":"<p><strong>Aim: </strong>To determine the prognostic value of routine hematological indices in patients undergoing carotid endarterectomy (CEA).</p><p><strong>Material and methods: </strong>As a retrospective single center study, we measured the systemic immune inflammation index (SII) and other systemic inflammatory parameters to estimate the morbidity and mortality of patients undergoing CEA. These parameters include inflammatory markers which are included in routine preoperative haematologic tests like complete blood count (CBC).</p><p><strong>Results: </strong>After the analysis of the collected datas from 72 patients, the results showed that inflammatory indices were significantly different in patients with different clinical courses.</p><p><strong>Conclusion: </strong>Inflammatory parameters calculated from routine preoperative hematologic parameters proved to be important predictive parameters that can be used in morbidity/mortality estimation of patients scheduled for CEA.</p>","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":" ","pages":"62-67"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143019317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gamma Knife Radiosurgery for Intractable Trigeminal Neuralgia - Comparative Study Between Single Versus Two Isocenter Targets.","authors":"Kashif Ahmed, Aurangzeb Kalhoro, Zaheen Shibli, Abdul Hashim","doi":"10.5137/1019-5149.JTN.44110-23.2","DOIUrl":"https://doi.org/10.5137/1019-5149.JTN.44110-23.2","url":null,"abstract":"<p><strong>Aim: </strong>To assess the safety and efficacy of using Two isocenter targets in Gamma Knife Radiosurgery (GKRS) for treating trigeminal neuralgia (TN) versus a single isocenter target solely at the root entry zone (REZ).</p><p><strong>Material and methods: </strong>A retrospective study was conducted.The study involved 171 patients with severe facial pain caused by TN. Pain intensity was measured using a pre/post-BNI scale. Group A (85 patients) received 90 Gy using a single isocenter at REZ with a 4mm collimator, while Group B (86 patients) received 90 Gy at two isocenters of the REZ and distal cisternal segment. Statistical analyses were done to assess differences between post-BNI scores and pain-free durations in the groups.</p><p><strong>Results: </strong>Both groups had a mean patient age of 50 years. Group A had a longer presurgical pain duration (98 months) than Group B (78 months). In Group A, 33% reported pain relief to BNI class II and 67% to class III, while in Group B, 70% reported pain relief to BNI class I and 30% to BNI class II. Group A had a 40% 8-week pain relief rate, while Group B had a higher percentage of painfree durations of 6-7 weeks (21%) and 9 weeks (39%). Group B had a higher incidence of post-op facial numbness (27% vs. 14% in Group A). Significant differences existed between post-BNI pain intensities and pain-free durations in both groups.</p><p><strong>Conclusion: </strong>Patients who received 90 Gy radiation at two isocenters had better outcomes than those with a single isocenter for GKRS. While Group B experienced earlier pain relief, Group A had fewer side effects. Two-isocenter GKRS is a safe and effective alternative for TN patients with a better pain management profile but an increased risk of facial hypoesthesia.</p>","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":"35 3","pages":"484-491"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144153063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cranial Dura Breach by Extradural Skull Base Hydatid Cyst Leading to Intraventricular Spread: A Novel Case of Intraventricular Spread.","authors":"Rakesh Redhu, Ashwin Kallianpur","doi":"10.5137/1019-5149.JTN.46443-24.2","DOIUrl":"10.5137/1019-5149.JTN.46443-24.2","url":null,"abstract":"<p><p>Intraventricular hydatid cysts are extremely rare. Till date, these cysts have been believed to originate from the ventricle itself. Of the various intraventricular cysts, primary solitary cysts are the most common ones. These cysts are purely intraventricular or partly parenchymal with an intraventricular spread. These cysts have so far never been reported to spread contiguously from the extradural location, breach the dura, and thereafter, migrate intraventricularly. Here, we present a unique case of intraventricular spread of an extracerebral hydatid cyst after a dural breach. The ability of hydatid cysts to breach the dura has not been described previously. The pathogenesis of the hydatid cyst has been discussed here along with its surgical and medical management.</p>","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":"35 2","pages":"345-348"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thromboelastography in Patients with Chronic Subdural Hematoma: A Prospective Pilot Study.","authors":"Xiaolin DU, Cheng Wang, Rukai Jiao, Xiaopeng Deng, Junquan Chen, Chengming Zhou, Kun Zhou","doi":"10.5137/1019-5149.JTN.47482-24.2","DOIUrl":"10.5137/1019-5149.JTN.47482-24.2","url":null,"abstract":"<p><strong>Aim: </strong>To evaluate association between chronic subdural hematoma (CSDH) and thromboelastography (TEG).</p><p><strong>Material and methods: </strong>A prospective pilot study was conducted on 52 patients with CSDH. The primary outcomes were CSDH severity, recurrence rate, and outcome. The secondary outcome was the association between TEG parameters and the risk factors of CSDH.</p><p><strong>Results: </strong>The association between the preoperative TEG parameters and the primary outcomes was compared. Results revealed no statistically significant association between the primary outcomes and admission modified Rankin scale score and follow-up GOS score. The R values significantly differed between patients with recurrence and those without (p=0.045). Further subgroup analysis of TEG parameters revealed that patients with R values &ge; 5 had a significantly high incidence of recurrence (1.231, 95% confidence interval [CI]: 0.973-1.557], p=0.025). However, further logistic regression analysis did not reveal significant results (1.198, 95% CI: 0.855-1.680, p=0.293). Moreover, the association between the preoperative TEG parameters and the secondary outcomes was compared. Results revealed a statistically significant association between the secondary outcomes and hematoma thickness and LY30 values (p=0.039), midline shift and Angle (p=0.043), and multiplicity of the hematoma cavity and MA (p=0.022). Further, the secondary outcomes were also significantly associated with postoperative TEG parameters such as multiplicity of the hematoma cavity and LY 30 value (p=0.011) and residual hematoma at follow-up (MA, p=0.001).</p><p><strong>Conclusion: </strong>Due to the small sample size, the efficacy of TEG parameters in predicting CSDH recurrence is unclear. However, TEG parameters are associated with the imaging characteristics of CSDH, and they can also be used to predict the absorption of hematoma. Nevertheless, large-scale prospective cohort studies should be performed to further validate the findings of this study.</p>","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":" ","pages":"644-651"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144513032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Traumatic Spinal Epidural Hematoma Associated with Cervical Nerve Root Avulsion without Vertebral Fractures: Case Report.","authors":"Rafael Aponte-Caballero, Valentina Osejo-Arcos, Luis C, Humberto Madrinan-Navia, Mario S, William Mauricio Riveros-Castillo, Javier G, Camilo E Peña","doi":"10.5137/1019-5149.JTN.46720-24.2","DOIUrl":"10.5137/1019-5149.JTN.46720-24.2","url":null,"abstract":"<p><p>Traumatic spinal epidural hematoma (TSEH) is a rare condition that may cause acute spinal cord compression and lead to irreversible neurological impairment. TSEH not only compresses the cord, but it can also worsen cervical nerve root avulsion. To our knowledge, only five cases of combined TSEH and cervical nerve root avulsion have been reported in the literature. We present the case of a 42-year-old woman who suffered a motorcycle accident. On admission, she presented with mild traumatic brain injury and cervical spine and right shoulder trauma. A physical examination revealed numbness and flaccid paresis in her right arm, compromising the C5 to T1 dermatomes and myotomes. MRI images showed evidence of a right anterolateral spinal epidural hematoma (SEH) that extended from the C2 to C7 vertebral levels. MRI and electromyography findings of the presence of a pseudomeningocele from the C4-C5 to C7-T1 levels indicating brachial plexus neurotmesis supported the presence of a cervical nerve root avulsion associated with TSEH. Cervical plexus syndrome requires a comprehensive diagnostic workup. SEH should be considered a cause of nerve root avulsion and brachial plexus syndrome. We believe that the extension of SEH into the intervertebral foramina could be a radiological sign related to nerve root avulsion.</p>","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":" ","pages":"672"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144513033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Syringic Acid Reduces Subarachnoid Hemorrhage?Induced Oxidative Damage in Rats.","authors":"Veysel Kiyak, Ozgur Demir, Fikret Gevrek, Osman Demir, Muzaffer Katar","doi":"10.5137/1019-5149.JTN.48257-24.3","DOIUrl":"10.5137/1019-5149.JTN.48257-24.3","url":null,"abstract":"<p><strong>Aim: </strong>To investigate the neuroprotective effects of various amounts of syringic acid (SA) on cerebral damage resulting from experimentally induced subarachnoid hemorrhage (SAH) in rats, utilizing both histological and biochemical analyses.</p><p><strong>Material and methods: </strong>In total, 40 male Wistar albino rats were randomly and equally assigned to four groups: Control, SAH, SAH + 50 mg/kg/day SA (po), and SAH + 250 mg/kg/day SA (po). The rats in the SAH, SAH + 50 mg/kg/day SA, and SAH + 250 mg/kg/day SA groups were induced with SAH by administering 0.15 mL of autologous blood, collected from each rat?s heart, into the subarachnoid space through the foramen magnum. On day 10th, the rats were sacrificed, and their blood and brain tissues were collected for biochemical, and histological analyses.</p><p><strong>Results: </strong>Glutathione peroxidase levels were considerably elevated in the SAH + 250 mg/kg/day SA group compared to both the control and SAH groups. Although not statistically significant, IL-6 levels were lower in the SAH + 250 mg/kg/day SA group compared with those in the control group. In the SAH + 250 mg/kg/day SA group, the histological and cellular damages in the cortical brain tissue reduced significantly.</p><p><strong>Conclusion: </strong>SA (250 mg/kg/day) ameliorated the oxidative and histopathological changes in blood profile and cerebral tissue of rats when exposed to experimentally induced SAH. Thus, SA can reduce secondary cerebral damage in an SAH-induced rat model.</p>","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":" ","pages":"570-576"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144513037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of Preoperative Imaging Factors and Development of a Nomogram Model for Predicting Recurrence in Patients with Septated Chronic Subdural Hematoma.","authors":"Xi Cao, Kunliang Huo, Liang Chen, Jiayu Li, Ziyin Yang, Jun Huang, Anliang Gao","doi":"10.5137/1019-5149.JTN.46686-24.1","DOIUrl":"10.5137/1019-5149.JTN.46686-24.1","url":null,"abstract":"<p><strong>Aim: </strong>To develop a nomogram model that provides a clinical prediction method for preventing septated chronic subdural hematoma (sCSDH) recurrence after surgery and serves as a reference for selecting surgical approaches.</p><p><strong>Material and methods: </strong>This study involved 237 patients diagnosed with sCSDH. Based on the recurrence status of the affected side during follow-up, patients were divided into a recurrence group (43 cases) and a non-recurrence group (194 cases). The imaging-related factors influencing the recurrence of sCSDH after surgery were initially screened using univariate analysis, followed by multivariate logistic regression analysis to identify independent risk factors. A nomogram model was developed using R software, and internal validation was conducted using the bootstrap method.</p><p><strong>Results: </strong>The univariate analysis revealed that cerebral atrophy, bilateral hematomas, preoperative midline shift distance, sCSDH typing, and neovascularization were the significant factors in the postoperative recurrence of sCSDH. However, the multivariate logistic regression analysis identified encephalatrophy, bilateral hematomas, and neovascularization as independent risk factors for sCSDH recurrence. Furthermore, the nomogram model analysis demonstrated good discrimination with an AUC of 0.764 (95% CI: 0.6958-0.8322), while the P-value of the Hosmer-Lemeshow test was 0.4382, indicating good consistency.</p><p><strong>Conclusion: </strong>Encephalatrophy, bilateral hematomas, and neovascularization are independent imaging risk factors associated with sCSDH recurrence. The developed nomogram model will enable clinicians to assess and identify patients at a higher risk of sCSDH recurrence, enabling them to formulate appropriate diagnostic and treatment strategies.</p>","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":"35 2","pages":"251-256"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}