Phlebology最新文献

筛选
英文 中文
Lipedema awareness and knowledge level among medical doctors in Turkey: A cross-sectional study highlighting the diagnosis and treatment gap. 土耳其医生对脂肪水肿的认识和知识水平:一项突出诊断和治疗差距的横断面研究。
Phlebology Pub Date : 2025-04-03 DOI: 10.1177/02683555251332998
Nazire Bagatir, Cigdem Cinar, Aysun Akansel, Mucahit Atasoy, Omer Faruk Bucak, Pinar Oztop, Evrim Coskun
{"title":"Lipedema awareness and knowledge level among medical doctors in Turkey: A cross-sectional study highlighting the diagnosis and treatment gap.","authors":"Nazire Bagatir, Cigdem Cinar, Aysun Akansel, Mucahit Atasoy, Omer Faruk Bucak, Pinar Oztop, Evrim Coskun","doi":"10.1177/02683555251332998","DOIUrl":"https://doi.org/10.1177/02683555251332998","url":null,"abstract":"<p><p>IntroductionLipedema is a chronic and progressive adipose tissue disorder that predominantly affects women. However, despite its high prevalence and severe negative impact on quality of life, it remains significantly underdiagnosed. The aim of this study was to assess the knowledge and awareness of medical doctors in Turkey regarding lipedema.MethodsA cross-sectional study was conducted among 508 medical doctors working in different clinical specialties in Turkey. A questionnaire was designed and validated by a panel of physical medicine and rehabilitation specialists. A total of 22 questions were asked to assess physicians' age, specialty, clinical experience, and institutional characteristics, as well as their knowledge of the clinical features, diagnostic criteria, and treatment modalities of lipedema.Results47.6% of the physicians were between 31 and 40 years of age. 29.3% of the participants had been practicing medicine for 0-5 years. 51% were familiar with the term \"lipedema\", but only 29.9% had seen or referred patients with lipedema. 51.4% of the participants answered \"no idea\" when asked about the lipoedema clinic and 50.9% answered \"no idea\" when asked about lipoedema treatment.ConclusionThis study identifies significant gaps in medical professionals' knowledge and awareness of lipedema in Turkey. The findings emphasize the necessity to incorporate lipedema-specific content in medical education and continuing professional development programs. Moreover, the establishment of multidisciplinary models of care, the dissemination of standardized clinical guidelines, and the promotion of public awareness campaigns are imperative to enhance early recognition and effective management of lipedema, which is often overlooked.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"2683555251332998"},"PeriodicalIF":0.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143775184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characterizing the description of pelvic congestion syndrome pain: A latent class analysis. 盆腔充血综合征疼痛的特征描述:潜类分析。
Phlebology Pub Date : 2025-04-01 Epub Date: 2024-09-25 DOI: 10.1177/02683555241287672
Sarah E Patel, Steven R Chesnut
{"title":"Characterizing the description of pelvic congestion syndrome pain: A latent class analysis.","authors":"Sarah E Patel, Steven R Chesnut","doi":"10.1177/02683555241287672","DOIUrl":"10.1177/02683555241287672","url":null,"abstract":"<p><p>ObjectivesChronic pelvic pain from pelvic congestion syndrome (PCS) is a complex condition disproportionately affecting women. PCS pain has been described as dull and achy, but emerging research indicates variances in the historical pain depictions. We aimed to identify the groups of pain characteristics experienced by women living with PCS using a latent class analysis and examine their predictive validity on quality of life, pain intensity, and pain management indicators.MethodsA secondary data analysis of cross-sectional survey data collected from 160 participants on a Facebook PCS support group was conducted. After evaluating the original 86 unique pain descriptors endorsed on the McGill Pain Questionnaire, descriptors endorsed by more than 30 participants were retained for analysis (<i>n</i> = 34).ResultsResults from the latent class analysis identified two latent classes: mild but consistent (44.4%) and intense and debilitating (55.6%). Between the two latent classes, there were clear patterns of pain endorsement to indicate that women in the two groups experience PCS pain differently. Compared to the second latent class (intense and debilitating), women in the first latent class (mild but consistent) experienced milder PCS associated pain and reported a significantly higher quality of life, satisfaction with their health, and less interference with sleep quality and sexual desire. Unfortunately, everyday activities (i.e., exercising, urinating, moving, standing, and working) were more likely to increase pain for women in the second latent class.ConclusionsDiagnosis and treatment of pelvic venous disorders are hindered by outdated evidence on the expected pain depictions. A comprehensive pain profile of PCS is needed to establish the effect on women's lifestyles, quality of life, and mental health.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"191-201"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142335875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Action of high intensity focused ultrasound (HIFU) ablation on the venous wall: Histopathological analysis, insights, and perspectives. 高强度聚焦超声(HIFU)消融对静脉壁的作用:组织病理学分析、见解与展望。
Phlebology Pub Date : 2025-04-01 Epub Date: 2024-10-29 DOI: 10.1177/02683555241297215
Paolo Casoni, Daniele Bissacco, Matteo Pizzamiglio, Emanuele Nanni, Luigi Serra
{"title":"Action of high intensity focused ultrasound (HIFU) ablation on the venous wall: Histopathological analysis, insights, and perspectives.","authors":"Paolo Casoni, Daniele Bissacco, Matteo Pizzamiglio, Emanuele Nanni, Luigi Serra","doi":"10.1177/02683555241297215","DOIUrl":"10.1177/02683555241297215","url":null,"abstract":"<p><p>In the medical field, ultrasound is commonly used for diagnostic imaging due to its ability to provide real-time images. However, High-Intensity Focused Ultrasound (HIFU) is also used for other clinical purposes, such as thermal tissue ablation. In the case of varicose veins, the potential role and benefits of HIFU have been known for a long time despite in-vivo results have mostly been preliminary and experimental, particularly regarding its effect on venous wall. The aim of this brief report is to describe how HIFU acts on venous wall in human incompetent great saphenous veins.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"211-213"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142549938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thanks to Reviewers. 感谢评论者。
Phlebology Pub Date : 2025-04-01 Epub Date: 2025-02-11 DOI: 10.1177/02683555251317083
{"title":"Thanks to Reviewers.","authors":"","doi":"10.1177/02683555251317083","DOIUrl":"https://doi.org/10.1177/02683555251317083","url":null,"abstract":"","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":"40 3","pages":"217-218"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143712571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Which dose of calcium dobesilate is more effective and safe in chronic venous insufficiency? Multicenter retrospective clinical trial. 哪种剂量的多贝西酸钙对慢性静脉功能不全更有效、更安全?多中心回顾性临床试验。
Phlebology Pub Date : 2025-04-01 Epub Date: 2024-09-19 DOI: 10.1177/02683555241286367
Oguz Arslanturk, Barıs Uymaz, Fatih Gumus
{"title":"Which dose of calcium dobesilate is more effective and safe in chronic venous insufficiency? Multicenter retrospective clinical trial.","authors":"Oguz Arslanturk, Barıs Uymaz, Fatih Gumus","doi":"10.1177/02683555241286367","DOIUrl":"10.1177/02683555241286367","url":null,"abstract":"<p><p>ObjectivesThis study aimed to evaluate the effectiveness and safety of different dosages of calcium dobesilate in the management of Chronic Venous Insufficiency (CVI) among patients in CEAP classes C3-C4.MethodsA comprehensive multicenter retrospective analysis was conducted, including patients aged 18-70 with CEAP class C3-C4 CVI. Participants were divided into two groups: one receiving 500 mg of calcium dobesilate twice daily and the other 1000 mg twice daily. Patient progress was monitored using the Global Index Score, CIVIC-20 Score, and precise measurements of ankle and calf circumferences over a 12-month period.ResultsThe higher dosage group (1000 mg twice daily) showed significant improvements in both symptom relief and edema reduction. Ankle circumference reduced notably at 6 months, while calf circumference and overall quality of life, measured by the Global Index Score, showed significant improvement by 12 months compared to the lower dosage group.ConclusionsHigher doses of calcium dobesilate markedly enhance the management of CVI symptoms and reduce edema more effectively than lower doses, particularly in patients with advanced CVI. These findings support the use of higher dosages for optimal treatment, though further research is needed to fully evaluate long-term safety.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"167-173"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142305469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Current state of education in venous diseases within vascular surgery training programs in Italy: A national web-based survey among residents. 意大利血管外科培训项目中的静脉疾病教育现状:一项针对住院医师的全国性网络调查。
Phlebology Pub Date : 2025-04-01 Epub Date: 2024-09-21 DOI: 10.1177/02683555241285526
Daniele Bissacco, Chiara Pisani, Paolo Verlato, Edoardo Forcella, Tiziana Aprea, Giulia Baldazzi, Ailin Belloni, Vanessa Di Mauro, Giuseppe Giuffrè, Marianna Mucignat, Michele Greco
{"title":"Current state of education in venous diseases within vascular surgery training programs in Italy: A national web-based survey among residents.","authors":"Daniele Bissacco, Chiara Pisani, Paolo Verlato, Edoardo Forcella, Tiziana Aprea, Giulia Baldazzi, Ailin Belloni, Vanessa Di Mauro, Giuseppe Giuffrè, Marianna Mucignat, Michele Greco","doi":"10.1177/02683555241285526","DOIUrl":"10.1177/02683555241285526","url":null,"abstract":"<p><p>BackgroundTo analyze the perception of vascular surgery trainees from Italian schools of Vascular Surgery regarding the level of practical and theoretical education in venous diseases.MethodsAn anonymous electronic survey was sent to Italian vascular surgery residents affiliated with 19 universities, asking about their training and experience in the management of venous diseases. The survey gathered information on the residents' personal and demographic details, their university's teaching program, operative experience in phlebology, as well as their confidence levels in performing various venous procedures, with the goal of analyzing the training and learning programs provided by Italian vascular surgery schools.ResultsThe analysis showed that 28% of programs do not include phlebology in the curriculum, and more than 40% of residents are unable to independently perform venous duplex ultrasound or treat venous ulcers. Additionally, most residents (over 70%) have limited weekly exposure to phlebology cases, with only 5% having access to a dedicated phlebology operating room. The vast majority of residents (96%) expressed a strong desire to deepen their knowledge and skills in this field, particularly in areas such as endovascular ablation techniques, venous duplex ultrasound, and management of deep venous disease.ConclusionsThe survey reveals significant limitations in phlebology education and hands-on experience within the current training programs, highlighting the need to standardize and enhance venous disease management education in order to ensure that future vascular surgeons are adequately equipped to provide high-quality care for patients with a wide range of venous disorders.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"174-181"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142305468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Can internal cooling radiofrequency catheters with local hypothermia eliminate the need for tumescent anesthesia? A single-center, retrospective, observational study. 内冷却射频导管与局部低温疗法能否消除对肿胀麻醉的需求?一项单中心、回顾性、观察性研究。
Phlebology Pub Date : 2025-04-01 Epub Date: 2024-09-27 DOI: 10.1177/02683555241287074
Gongmin Rim, Kwanyong Hyun, Deog Gon Cho, Jaemin Cho
{"title":"Can internal cooling radiofrequency catheters with local hypothermia eliminate the need for tumescent anesthesia? A single-center, retrospective, observational study.","authors":"Gongmin Rim, Kwanyong Hyun, Deog Gon Cho, Jaemin Cho","doi":"10.1177/02683555241287074","DOIUrl":"10.1177/02683555241287074","url":null,"abstract":"<p><p><b>Background:</b> Tumescent anesthesia not only prolongs the operation time but also induces postoperative pain, bruising, and swelling. This study investigated the effectiveness and safety of tumescentless RFA using an internal cooling system with a VENISTAR catheter and local hypothermia. <b>Methods:</b> We retrospectively analyzed patients who had undergone RFA for above-knee (AK) great saphenous vein (GSV) between March 2023 and November 2023. We compared the efficacy and safety of tumescentless RFA between group T (conventional tumescent group, <i>n</i> = 50) and group N (non-tumescent group, <i>n</i> = 59). <b>Results:</b> The operative time was shorter in group N than in group T (group N: 31.37 min, group T: 42.31 min, <i>p</i> < .01), with no severe adverse events occurred in either group, such as endovenous heat-induced thrombosis or deep vein thrombosis. Postoperative pain (Group N, 0.53% vs Group T, 0.52%; <i>p</i> = .86), postoperative complications such as bruising (Group N, 6.78% vs Group T, 4%; N= .34) and paresthesia (Group N, 1.7% vs Group T, 6%; <i>p</i> = .27) showed no significant difference between the two groups on postoperative day 10. <b>Conclusion:</b> Tumescentless RFA with internal cooling and local hypothermia shows promising results with minimal complications. This novel approach represents a recent advancement in endovenous RFA that omits additional tumescent anesthesia.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"202-210"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142335874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The profile beyond leg pain: In basis of central sensitization, kinesiophobia, and body awareness in patients with chronic venous disease. 腿痛之外的概况:慢性静脉疾病患者的中枢敏感性、运动恐惧症和身体意识的基础。
Phlebology Pub Date : 2025-04-01 Epub Date: 2024-09-24 DOI: 10.1177/02683555241286385
Zilan Bazancir-Apaydin, Elif Sakizli Erdal, Ilke Keser, Dilek Erer
{"title":"The profile beyond leg pain: In basis of central sensitization, kinesiophobia, and body awareness in patients with chronic venous disease.","authors":"Zilan Bazancir-Apaydin, Elif Sakizli Erdal, Ilke Keser, Dilek Erer","doi":"10.1177/02683555241286385","DOIUrl":"10.1177/02683555241286385","url":null,"abstract":"<p><p><b>Objective:</b> Leg pain has long been underestimated despite being one of the most important symptoms of chronic venous disease (CVD). Studies investigating leg pain and psychosocial profile in CVD are limited. The study aimed to investigate leg pain, central sensitization, kinesiophobia, and body awareness in patients with CVD. <b>Methods:</b> The ninety-eight patients (80 female, 18 male) diagnosed with CVD were included in the study. The severity of leg pain was evaluated with the Visual Analog Scale (VAS). The patients were assessed with the Central Sensitization Inventory (CSI-A and B) for central sensitization-related symptoms and -positivity, the Body Awareness Questionnaire (BAQ) for body awareness, and the Tampa Kinesiophobia Scale (TKS) for kinesiophobia. The cut-off score was admitted as 41 for TKS. <b>Results:</b> The leg pain (mean (SD) = 4.3 ± 2) and body awareness (mean (SD) = 82.4 ± 22) were moderate levels in patients with CVD. Nearly half of the patients (<i>n</i> = 46, 46.9%) had both central sensitization positivity and elevated kinesiophobia (<i>n</i> = 46, 47%). The CSI was correlated with the VAS (r = 0.32, <i>p</i> = .001), TKS (r = 0.40, <i>p</i> < .001), and BAQ (r = 0.20, <i>p</i> = .048). Significant correlations were determined between Body Mass Index and TKS (r = 0.48, <i>p</i> < .001) and BAQ (r = -0.31, <i>p</i> = .002). Also, the patients with a TKS score ≥41-points had higher CSI-A scores (<i>p</i> = .002) than those with a TKS score< 41. <b>Conclusions:</b> Leg pain, central sensitization, and kinesiophobia are commonly seen in patients with CVD, and central sensitization seems to have a negative effect on leg pain, kinesiophobia, and body awareness. The profile beyond pain should be evaluated in detail, and various rehabilitation strategies need to be developed to manage central sensitization, interoception, kinesiophobia, and weight control in patients with CVD.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"182-190"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142309571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Deciphering the association between gut microbiome and varicose veins: A mendelian randomization study. 解读肠道微生物群与静脉曲张之间的关系:一项孟德尔随机研究。
Phlebology Pub Date : 2025-03-28 DOI: 10.1177/02683555251329406
Yu Tian, Furong Hao, Jiantao Zhang, Yuxuan Qian, Jiahao Liu, Qianhui Bao, Haipeng Shi, Tianjie Li, Tao Yang
{"title":"Deciphering the association between gut microbiome and varicose veins: A mendelian randomization study.","authors":"Yu Tian, Furong Hao, Jiantao Zhang, Yuxuan Qian, Jiahao Liu, Qianhui Bao, Haipeng Shi, Tianjie Li, Tao Yang","doi":"10.1177/02683555251329406","DOIUrl":"https://doi.org/10.1177/02683555251329406","url":null,"abstract":"<p><p><b>Background:</b> Despite the well-documented influence of traditional risk factors on varicose veins, the potential causal role of the gut microbiome in this condition remains underexplored. This study aims to elucidate the association between specific gut microbial taxa and varicose veins using a Mendelian Randomization (MR) approach. <b>Methods:</b> Utilizing genome-wide association study datasets from the MiBioGen Consortium and the Finnish database, this study carefully selected instrumental variables based on their genetic association with the gut microbiome and stringent statistical criteria. Multiple MR techniques were applied to analyze the data, accompanied by comprehensive sensitivity analyses to ensure the reliability of the causal relationships between the gut microbiota and varicose veins. <b>Results:</b> The study identified three microbial taxa-genus <i>Terrisporobacter</i>, <i>Coprococcus2</i>, and <i>Ruminococcus</i> gnavus group-as protective factors against varicose veins. Conversely, the family Ruminococcaceae, genus <i>Flavonifractor</i>, and genus <i>Ruminococcaceae</i>UCG009 were associated with an increased risk of developing varicose veins. Bidirectional analyses indicated that the presence of varicose veins does not influence the abundance of these microbiota groups. <b>Conclusion:</b> The results of this study support a relationship between specific gut microbiota and varicose veins, revealing potential new targets for therapeutic intervention. These insights not only deepen our understanding of the pathophysiology of varicose veins but also provide a theoretical basis for future medical applications, highlighting the potential value of microbiome research in the prevention and treatment strategies for varicose veins.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"2683555251329406"},"PeriodicalIF":0.0,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143736324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retrospective evaluation of the results of ultrasound-accelerated catheter-directed tombolysis in acute-subacute pulmonary embolism patients. 超声加速导管定向溶栓治疗急性-亚急性肺栓塞疗效的回顾性评价。
Phlebology Pub Date : 2025-03-20 DOI: 10.1177/02683555251329766
Ali Fuat Karaçuha, İlyas Memmedyarov, Ahmet Kayan, Çağdaş Baran, Evren Özçinar, Nur Dikmen, Mustafa Şirlak, Sadık Eryilmaz
{"title":"Retrospective evaluation of the results of ultrasound-accelerated catheter-directed tombolysis in acute-subacute pulmonary embolism patients.","authors":"Ali Fuat Karaçuha, İlyas Memmedyarov, Ahmet Kayan, Çağdaş Baran, Evren Özçinar, Nur Dikmen, Mustafa Şirlak, Sadık Eryilmaz","doi":"10.1177/02683555251329766","DOIUrl":"https://doi.org/10.1177/02683555251329766","url":null,"abstract":"<p><p>ObjectivesAcute pulmonary embolism (PE) is one of the most serious forms of venous thromboembolism (VTE) with high mortality and morbidity. PE may present with right ventricular dysfunction and hemodynamic disturbances. Early diagnosis and appropriate treatment approaches play a critical role in improving survival. In this study, we evaluated the efficacy and safety of catheter-mediated thrombolytic therapy in intermediate-high-risk PE patients.MethodsOur retrospective study was conducted at Ankara University between 2015 and 2020 and 66 intermediate-high-risk PE patients were analyzed. Clinical, biochemical and echocardiographic data of the patients were analyzed and their response to treatment was evaluated. The primary endpoint was 30-day mortality and secondary endpoints were hemodynamic improvement, length of hospitalization and complication rates.ResultsThe mean age of the patients was 65 years and all of them presented with a diagnosis of symptomatic PE. After treatment, significant improvement was observed in right ventricular function, RV/LV ratio, ProBNP and Troponin I levels decreased significantly. Pulmonary artery pressures decreased and hemodynamic parameters improved. The early mortality rate after the procedure was 3% and the rate of major bleeding was low.ConclusionsCatheter-mediated thrombolytic therapy provides hemodynamic improvement in intermediate-high-risk PE patients, while offering a low bleeding risk. Our results suggest that this therapy may be a safe and effective alternative. However, long-term results should be evaluated in large-scale, randomized studies.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"2683555251329766"},"PeriodicalIF":0.0,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143672159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信