Phlebology最新文献_第5页

Incidence and management of symptomatic pelvic venous disorders in patients with lower extremity varicose veins. 下肢静脉曲张患者症状性盆腔静脉疾病的发生率和治疗。

Phlebology Pub Date : 2025-06-11 DOI: 10.1177/02683555251351184

Christos Dimopoulos, Ioannis Papastefanou, Panagiotis Theodoridis, Nikolaos Iatrou, Theodosios Bisdas

{"title":"Incidence and management of symptomatic pelvic venous disorders in patients with lower extremity varicose veins.","authors":"Christos Dimopoulos, Ioannis Papastefanou, Panagiotis Theodoridis, Nikolaos Iatrou, Theodosios Bisdas","doi":"10.1177/02683555251351184","DOIUrl":"https://doi.org/10.1177/02683555251351184","url":null,"abstract":"BackgroundPelvic venous disorders (PeVD) are a recognized cause of venous origin chronic pelvic pain (VO-CPP) in women. However, the prevalence and management of PeVD in patients with lower extremity varicose veins remain understudied. This study assesses the incidence of PeVD among women with superficial venous insufficiency (SVI) and evaluates the role of transvaginal ultrasound (TVUS) as a screening tool.MethodsA retrospective analysis was conducted on 350 female patients with SVI (CEAP C2-C6) from January 2021 to December 2023. SVI was confirmed by duplex ultrasound (DUS). All patients were evaluated for CPP at the initial visit. In those with CPP, pelvic symptom management preceded any lower limb intervention. Symptomatic patients were assessed using the Pelvic Venous Congestion Symptom Scale (PVCSS), Visual Analog Scale (VAS), and TVUS for features suggestive of PeVD. In confirmed cases, diagnostic venography and ovarian vein embolization were performed, followed by saphenous vein ablation.ResultsPeVD was identified in 11% (37/350) of patients. TVUS revealed pelvic varicosities, ovarian veins dilation >6 mm, and reflux, confirmed by venography. Of the 37 patients, 41% (15/37) underwent embolization, while 59% opted for conservative management. Post-treatment, median PVCSS scores improved from 20 to 2 (p < 0.001), and VAS scores from 8 to 0 (p < 0.001), indicating significant symptom relief. Mean follow-up was 17 months, with assessments at 1, 6, and 12 months. Reintervention-free survival was 86.7%.ConclusionApproximately one in 10 women with SVI have symptomatic PeVD, highlighting the importance of targeted screening. TVUS serves as a useful non-invasive diagnostic tool. Further studies are needed to clarify optimal treatment strategies and long-term outcomes in this population.","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"2683555251351184"},"PeriodicalIF":0.0,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144268280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quantifying superficial vein morphology with near-infrared imaging during venous congestion. 静脉充血时浅静脉形态的近红外成像定量分析。

Phlebology Pub Date : 2025-06-10 DOI: 10.1177/02683555251348754

Henrique Silva, Carlota Rezendes

{"title":"Quantifying superficial vein morphology with near-infrared imaging during venous congestion.","authors":"Henrique Silva, Carlota Rezendes","doi":"10.1177/02683555251348754","DOIUrl":"https://doi.org/10.1177/02683555251348754","url":null,"abstract":"The venous system plays a key role in clinical practice but remains underassessed due to the limited accessibility of conventional imaging tools. Near-infrared reflection illumination (NIRI) devices (\"vein finders\"), though recently introduced to assist venipuncture, have potential for broader vascular assessment. Our aim was to investigate the feasibility of a NIRI device to quantify the morphology of superficial hand veins and evaluate their response to a transient hemodynamic stress induced by suprasystolic limb occlusion. The dorsal hand veins of 14 healthy adults (21.5 ± 4.2 y.o.) were continuously recorded during a procedure consisting of a 5 min baseline, 3 min arm occlusion (200 mmHg), and 3 min recovery phases. Morphological parameters including vein width, branching angles, asymmetry indices, junctional exponent deviation, and optimality ratio, were extracted from three metacarpal veins and their tributaries. Nonparametric statistics were used to compare parameters between phases (p < .05). Occlusion led to a significant increase in the width of both receiving and tributary veins (p < .001), reflecting venous pooling. However, branching geometry remained largely unchanged, suggesting structural resilience. Junctional exponent deviation remained low, in agreement with Murray's law. Near-infrared vein finders enable real-time, non-invasive assessment of superficial venous morphology and compliance. Their sensitivity to dynamic vascular changes, combined with potential for integration with automated analysis tools, supports their broader use in vascular diagnostics, preoperative planning, and bedside monitoring.","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"2683555251348754"},"PeriodicalIF":0.0,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144268281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Corrigendum to "Regarding: 899 serious adverse events including 13 deaths, 7 strokes, 211 thromboembolic events, and 482 immune reactions: The untold story of cyanoacrylate adhesive closure. Parsi K et al." 《关于：899起严重不良事件，包括13起死亡、7起中风、211起血栓栓塞事件和482起免疫反应：氰基丙烯酸酯胶粘剂闭合的未知故事》的勘误。Parsi K等人。”

Phlebology Pub Date : 2025-06-09 DOI: 10.1177/02683555251346418

引用次数: 0

Safety and efficacy of flush endovenous ablation of the great saphenous vein: A retrospective study. 大隐静脉冲洗消融的安全性和有效性：一项回顾性研究。

Phlebology Pub Date : 2025-06-09 DOI: 10.1177/02683555251348768

Ahmed Azhar Ali, Ahmad ElGhamrey, Omar Ahmed AbuAlata, Ehab M Saad, Hossam ElWakeel

{"title":"Safety and efficacy of flush endovenous ablation of the great saphenous vein: A retrospective study.","authors":"Ahmed Azhar Ali, Ahmad ElGhamrey, Omar Ahmed AbuAlata, Ehab M Saad, Hossam ElWakeel","doi":"10.1177/02683555251348768","DOIUrl":"https://doi.org/10.1177/02683555251348768","url":null,"abstract":"Aim: To assess the safety and efficacy of endovenous ablation of great saphenous varicose veins with flush ablation at the saphenofemoral junction.Methods: A retrospective study was conducted on consecutive patients with varicose veins related to the great saphenous vein (GSV) and undergoing endovenous thermal ablation between January 2020 and July 2024. All patients underwent either endovenous laser or microwave ablation. Primary endpoints included technical success and absence of endothermal heat-induced thrombosis (EHIT) ≥ 2. Secondary endpoints included deep vein thrombosis (DVT), pulmonary embolism (PE), recurrence, days to return to normal daily activity, and reintervention. Follow-up was performed at 1 week, 6 months, and annually thereafter. Technical success was defined as successful flush catheter placement at the SFJ under duplex guidance. Recurrence was assessed through clinical examination and duplex ultrasound.Results: 69 patients (79 limbs) were included with a mean age of 39.1 ± 12.5 y, and 30 were of male sex (43.5%). Technical success was achieved in all limbs. EHIT ≥2 was not documented at the first postoperative outpatient visit, and no DVT or PE were noted during follow-up (20.4 ± 11 months). Recurrence was documented in 2 limbs (2.5%). One limb required surgical reintervention, and the days to return to daily activity recorded a median of 15 days (IQR 10 - 30).Conclusion: Flush endovenous ablation may be a safe and effective technique for treating great saphenous varicose veins, demonstrating a low incidence of recurrence and deep vein thrombosis while maintaining high technical and clinical success rates. Our findings contribute to the growing body of evidence supporting flush ablation strategies and highlight the need for further research to optimise procedural guidelines.","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"2683555251348768"},"PeriodicalIF":0.0,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144251688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of gait parameters, functionality and health status in patients with lower extremity lymphedema and healthy controls. 下肢淋巴水肿患者与健康对照者步态参数、功能和健康状况的比较

Phlebology Pub Date : 2025-06-06 DOI: 10.1177/02683555251348774

Ezgi Ergin, Didem Karadibak, Merve Celik

{"title":"Comparison of gait parameters, functionality and health status in patients with lower extremity lymphedema and healthy controls.","authors":"Ezgi Ergin, Didem Karadibak, Merve Celik","doi":"10.1177/02683555251348774","DOIUrl":"https://doi.org/10.1177/02683555251348774","url":null,"abstract":"ObjectivesTo compare gait parameters, functionality (muscle strength, balance, exercise capacity) and health status (kinesiophobia, fatigue, quality of life) in lower extremity lymphedema patients and healthy controls and to determine correlations between exercise capacity, gait parameters, muscle strength, balance, quality of life and lymphedema severity.MethodsTwenty-two lymphedema patients and 20 healthy controls participated in the study. Participants' demographic and medical characteristics were recorded. Muscle strength, endurance, balance, functional exercise capacity, gait parameters, kinesiophobia, fatigue and quality of life were assessed with dynamometer, 30-s chair stand test, Biodex, 6-min walk test (6MWT), 8-m test (8-MWT), Tampa Scale, Fatigue Severity Scale and Short Form-36, respectively.ResultsLymphedema patients had lower muscle strength and endurance, 6MWT distance, speed, cadence and stride length, 8-mWT speed, cadence and left stance phase, and higher swing phase-left and single support phase-right compared to healthy controls (p < .05). Balance parameters were worse in lymphedema patients compared to healthy controls (p < .05). Quality of life was lower and kinesiophobia and fatigue levels were higher in lymphedema patients compared to healthy controls (p < .05). Significant correlations were found between 6MWT distance, speed and stride length, 8-mWT speed and stride lengths and lymphedema severity, muscle strength, balance, and quality of life (p < .05). Multiple regression analyses identified balance and lymphedema severity as predictors for 6MWT distance, speed, and stride length.ConclusionsLymphedema patients have reduced muscle strength, exercise capacity, quality of life, and increased kinesiophobia and fatigue. Lymphedema negatively impacts gait and balance. Gait parameters are correlated with muscle strength, balance, quality of life and lymphedema severity in lymphedema patients.","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"2683555251348774"},"PeriodicalIF":0.0,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144236366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Venous hemodynamics in active and passive calf movements in healthy adults. 健康成人主动和被动小腿运动的静脉血流动力学。

Phlebology Pub Date : 2025-06-05 DOI: 10.1177/02683555251348755

Luiz Fernando Lima Albernaz, Marcondes Antônio de Medeiros Figueiredo, Daiane Taís Schlindwein Albernaz, Fabricio Rodrigues Santiago, Mateus Lusa Bordin, Yung-Wei Chi

{"title":"Venous hemodynamics in active and passive calf movements in healthy adults.","authors":"Luiz Fernando Lima Albernaz, Marcondes Antônio de Medeiros Figueiredo, Daiane Taís Schlindwein Albernaz, Fabricio Rodrigues Santiago, Mateus Lusa Bordin, Yung-Wei Chi","doi":"10.1177/02683555251348755","DOIUrl":"https://doi.org/10.1177/02683555251348755","url":null,"abstract":"ObjectiveThe physiological effects produced by the calf pump are essential in multiple aspects of vascular health, and their absence leads to stasis which directly relates to venous insufficiency. Therefore, muscle activity has been considered a key element in calf pump function. In the present study, we used a mechanical foot board with passive range of motion including stimulated dorsiflexion and plantar flexion and compared the hemodynamic effects to those obtained during active voluntary movement.Methods11 healthy adult volunteers participated in an intervention study. In Intervention 1, the participants performed voluntary dorsiflexion and plantar flexion, and in Intervention 2, the same participants used the passive PumpCare® device (OAK Healthtech, Brazil). Both legs were examined, but data were collected from the right leg. Femoral vein blood flow was assessed by ultrasound, and venous pump capacity (V0) by photoplethysmography. Anthropometric data were collected to investigate their correlation with femoral vein blood volume.ResultsThe mean femoral vein blood flow was 286 mL/min with active calf movements and 288 mL/min with passive calf movements (p = .929). Flow peaks were produced during dorsiflexion, that is, during stretching of the posterior muscle groups, returning to baseline levels after stopping the movement in both interventions. The mean maximal venous pump capacity measured by photoplethysmography was 3.7% with active calf movements and 3.5% with passive calf movements (p = .141).ConclusionIn this study, passive calf movements were able to promote a mean femoral vein volume flow comparable to the physiological effect produced by active calf movements in healthy adults. This appears to contradict the current understanding of the importance of calf muscle contraction in producing venous return.","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"2683555251348755"},"PeriodicalIF":0.0,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144228220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Potential therapeutic targets for deep vein thrombosis: A proteome-wide Mendelian randomization study. 深静脉血栓的潜在治疗靶点：一项蛋白质组范围的孟德尔随机研究。

Phlebology Pub Date : 2025-06-04 DOI: 10.1177/02683555251337253

JiaHao Liu, YuanZhuo Du, XiaoQiang Liu, Jing Xiong, Bin Fu

{"title":"Potential therapeutic targets for deep vein thrombosis: A proteome-wide Mendelian randomization study.","authors":"JiaHao Liu, YuanZhuo Du, XiaoQiang Liu, Jing Xiong, Bin Fu","doi":"10.1177/02683555251337253","DOIUrl":"https://doi.org/10.1177/02683555251337253","url":null,"abstract":"BackgroundThe incidence of deep vein thrombosis (DVT) of the lower extremities is threatening people's health. The development of drug targets for the treatment of DVT is necessary.MethodsWe mainly conducted a proteome-wide Mendelian randomization (MR) study to explore the causal associations of plasma proteins with DVT of the lower extremities. Protein quantitative trait locis were derived from DECODE with 35,559 participants. Multiple analysis methods and two replication analyses were implemented to guarantee the reliability of the results. Mediation MR, protein-protein associations and pathway enrichment analyses were used to reveal the potential mechanisms. Finally, druggability evaluation and phenome-wide MR analysis were performed to assess the priority for drug development of these drug targets.ResultsWe identified 12 plasma proteins showing significant causal associations with DVT of the lower extremities. Genetically predicted higher serum concentration of MAP1LC3A, LRP12, VWF, F2, SYK, F11, KLKB1, and LRP4 were associated with an increased risk of DVT, while higher levels of the serum SERPINE2, XXYLT1, PMVK, and RGS18 can act as protective factors for DVT. LRP12 and F11 had the highest convincing evidence. In mediation analysis, we found four pathways, including F2-Triglycerides-DVT, LRP4-Triglycerides-DVT, MAP1LC3A-eGFR-DVT, and MAP1LC3A-Creatinine-DVT. In druggability evaluation, F11, F2, KLKB1, SYK, and VWF have been developed as drugs related to coagulation.ConclusionThis study identified 12 protein targets associated with DVT of the lower extremities and offered promising insights for developing therapeutic agents and biomarkers for DVT screening.","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"2683555251337253"},"PeriodicalIF":0.0,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144218093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A retrospective study on the diagnostic value of ultrasonography for primary vascular leiomyosarcoma misdiagnosed as deep vein thrombosis. 超声对误诊为深静脉血栓形成的原发性血管平滑肌肉瘤诊断价值的回顾性研究。

Phlebology Pub Date : 2025-06-02 DOI: 10.1177/02683555251348784

Xiaorong Wen, Zhoupeng Wu

引用次数: 0

"Comparing sub-bandage pressure and stiffness dynamics in two two-component compression systems for the lower limb: Influence of skill level and partial compression layer addition". 比较两种双组份下肢压缩系统的绷带下压力和刚度动态：技术水平和部分压缩层添加的影响。

Phlebology Pub Date : 2025-06-02 DOI: 10.1177/02683555251347057

Sarah Moonen, Tessa De Vrieze, Erik Fransen, Lot Demuynck, Hanne Verbelen, Jill Meirte, Ulrike Van Daele, Nick Gebruers

{"title":"\"Comparing sub-bandage pressure and stiffness dynamics in two two-component compression systems for the lower limb: Influence of skill level and partial compression layer addition\".","authors":"Sarah Moonen, Tessa De Vrieze, Erik Fransen, Lot Demuynck, Hanne Verbelen, Jill Meirte, Ulrike Van Daele, Nick Gebruers","doi":"10.1177/02683555251347057","DOIUrl":"https://doi.org/10.1177/02683555251347057","url":null,"abstract":"BackgroundTwo-component cohesive compression systems are available for compression therapy.ObjectivesTo assess the sub-bandage pressure and stiffness of the two-component compression systems, Coban and CoFlex, and to investigate how an additional partial compression layer after two hours and the experience of the therapist impact these outcomes.MethodsThe study examined 19 patients whose lower limbs were bandaged by either a trainee or an experienced physical therapist. Sub-bandage pressures were measured using PicoPress® sensors placed 10 cm and 25 cm proximal to the medial malleolus. Additionally, the Static Stiffness Index (SSI) and Dynamic Stiffness Index (DSI) were calculated.ResultsThe addition of a partial compression layer on the ventral side of the leg significantly increased sub-bandage pressure and DSI. SSI effects were significant at 10 cm, but not at 25 cm height. Coban generated significantly higher pressures than CoFlex, while the level of experience of the therapist showed no significant influence.ConclusionsThe addition of a partial compression layer effectively increases sub-bandage pressure, with Coban exerting higher pressure than CoFlex. However, the level of experience of the therapist does not significantly influence the compression outcomes.","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"2683555251347057"},"PeriodicalIF":0.0,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144201263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Audit of co-morbidity patterns and 5-year survival among patients presenting to a rapid access leg ulcer service. 对快速获得腿部溃疡服务的患者的合并症模式和5年生存率的审计。

Phlebology Pub Date : 2025-06-01 Epub Date: 2024-12-09 DOI: 10.1177/02683555241306998

Ahmmad Alfatih Ahmmad, Tayyaub Mansoor, Doireann Joyce, Daniel Westby, Colum Keohane, Marie O'Shaughnessy, Stewart Walsh

{"title":"Audit of co-morbidity patterns and 5-year survival among patients presenting to a rapid access leg ulcer service.","authors":"Ahmmad Alfatih Ahmmad, Tayyaub Mansoor, Doireann Joyce, Daniel Westby, Colum Keohane, Marie O'Shaughnessy, Stewart Walsh","doi":"10.1177/02683555241306998","DOIUrl":"10.1177/02683555241306998","url":null,"abstract":"Background: While leg ulceration is common, data regarding long-term is limited. Historical data indicate that approximately 50% of leg ulcer patients die within 5 years of presentation. However, little is known regarding survival outcomes in contemporary patient populations. This retrospective study aimed to assess 5-year survival in patients attending a vascular leg ulcer clinic. Objectives: To evaluate 5-year survival among patients with leg ulcers and to analyse the effect of ulcer aetiology and patient co-morbidities on survival. Methods: Over 30 months (2016 to 2018), 119 new patients were assessed at the leg ulcer clinic and followed over 5 years. Baseline co-morbidities, ulcer type, interventions performed, and 5-year survival were recorded. Survival was calculated using Kaplan-Meier curves. Co-morbid burden and survival were compared between venous and arterial/mixed patients. Results: Overall 5-year survival was 74%. Venous patients fared better than arterial/mixed patients (5-year mortality 16/88 vs 15/31; p < .01 log-rank test). Arterial/mixed patients had a greater burden of co-morbidities. In multivariate regression modelling, the presence of three or more co-morbidities at presentation was the only significant predictor of mortality. Conclusions: Overall, 5-year survival for leg ulcer patients has improved compared to historical data but remains static for arterial/mixed patients.","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"339-344"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142796771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0