Phlebology最新文献

{"title":"Effects of multimodal exercise program on edema, pain, exercise capacity, lower extremity muscle strength and function in patients with lipedema.","authors":"Elif Sakizli Erdal, Canan Ergin, Miray Haspolat, Burak Erturk, Ilke Keser","doi":"10.1177/02683555251343148","DOIUrl":"https://doi.org/10.1177/02683555251343148","url":null,"abstract":"<p><p><b>Objectives:</b> This study aimed to examine the effects of a multimodal exercise program on edema, pain, exercise capacity, lower extremity muscle strength, and function in patients with lipedema.<b>Methods:</b> The patients diagnosed with lipedema were randomly assigned to either the exercise (<i>n</i>: 11) or control (<i>n</i>: 11) groups. The exercise group participated in supervised group exercises focusing on aerobic and strengthening, twice a week for 6 weeks. The control group received training on physical activity additionally lipedema management. Sociodemographic and clinical characteristics were recorded. Edema (circumference measurements and local tissue water-LTW%), pain intensity (Visual Analogue Scale-VAS) and pressure pain threshold (Algometer), functional exercise capacity (Six minute walk test-6MWT), lower extremity muscle strength (Handheld dynamometer), lower extremity muscle strength/endurance (Sit-to-stand test) and lower extremity function (Lower Extremity Functional Scale-LEFS) were evaluated.<b>Results:</b> In the exercise group, significant reductions in pain during rest, activity, and nighttime, 6MWT distance, quadriceps and hip muscle strength, lower extremity strength/endurance, and function were observed (<i>p</i> < .05). When comparing the groups, no significant differences were found (<i>p</i> > .05); however, clinically, there were differences in limb volumes, pain reduction, muscle strength, and functional improvements, with medium to large effect sizes.<b>Conclusion:</b> The main findings of this study highlight the benefits of structured multimodal exercises for patients with lipedema to improve pain, limb volumes, exercise capacity, lower extremity muscle strength, endurance, and functionality.<b>Clinical trials number:</b> NCT06811961.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"2683555251343148"},"PeriodicalIF":0.0,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144083131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A systematic review and meta-analysis of venous thromboembolism risk in surgical patients with recent air travel.","authors":"Jessie Shea, Avik Ghosh, Benedict Rh Turner, Alun H Davies, Sarah Onida","doi":"10.1177/02683555251342912","DOIUrl":"https://doi.org/10.1177/02683555251342912","url":null,"abstract":"<p><p>ObjectiveRisk of venous thromboembolism (VTE) is classically associated with recent surgery; additionally, long-haul air travel is a known VTE risk factor. This meta-analysis aimed to estimate the post-operative VTE risk associated with recent air travel.MethodsEmbase, Medline, Cochrane and Scopus databases were accessed from inception to May 2024. Inclusion criteria were any study design of participants undergoing surgical intervention with recent air travel, reporting VTE incidence. Papers were screened and data extracted independently by two reviewers, then pooled using fixed and random effects. The primary outcome was pooled VTE rate, with secondary outcomes of pooled rate of deep vein thrombosis (DVT) and pulmonary embolism (PE). Subgroup analyses of pre- and post-operative flight, flight >4 h and high VTE risk surgery were conducted. The ROBINS-I tool was used to assess risk of bias.ResultsSeven retrospective studies were included in the analysis, totalling 24,975 patients. The pooled VTE odds ratio (OR) in the flying plus surgery group was 1.96 (95% CI: 0.54-7.08). For surgery with post-operative flight, the VTE OR was 1.31 (95% CI: 0.63-2.71), whilst for surgery with pre-operative flight the OR was 7.86 (95% CI: 0.23-265.26). In a subgroup analysis of air travel >4 h, the VTE OR was 2.35 (95% CI: 0.29-19.36). In the subgroup analysis of high VTE risk surgery, the VTE OR was 1.20 (95% CI: 0.45-3.20). Three studies reported DVT/PE incidence specifically. For surgery and recent air travel, the pooled DVT rate was 0.67% (95% CI: 0.31%-1.51%) versus 0.45% (95% CI: 0.10%-2.00%) in surgery alone. For surgery and recent air travel, the pooled PE rate was 0.41 (95% CI: 0.00%-1.29%) versus 0.55% (95% CI: 0.31%-0.86%) for surgery alone.ConclusionThis meta-analysis suggests that air travel confers no additional VTE risk for patients undergoing surgical intervention. However, this does not account for confounding factors. Future research should risk score then propensity match participants to generate higher quality evidence.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"2683555251342912"},"PeriodicalIF":0.0,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144045735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of lower leg edema in the late afternoon may be associated with decreased blood flow in the leg in women in the luteal phase.","authors":"Yoriko Sei, Tomonori Kishino, Shohei Shibasaki, Keiichiro Harashima, Konomi Sakata, Hiroaki Ohnishi, Takashi Watanabe","doi":"10.1177/02683555251341395","DOIUrl":"10.1177/02683555251341395","url":null,"abstract":"<p><p>ObjectivesLower leg edema is common in the late afternoon even in healthy individuals and could involve venous blood flows. Women appear more likely to develop lower leg edema, possibly due to the menstrual cycle. However, this phenomenon has not been quantitatively investigated using imaging. This study therefore used sonography to investigate sex-dependent impacts on physiological lower leg edema, in relation to venous blood flows in the legs and the menstrual cycle.MethodsParticipants comprised 54 healthy young adults (30 men, 24 women; mean age, 21 ± 1 years). Thickness of the papillary dermis and thickness and echogenicity of the subcutaneous adipose tissue were measured in the lower leg. Popliteal vein hemodynamics were investigated using Doppler sonography. Values were compared between late afternoon and morning. Each comparison was performed for men, women in the follicular, and women in the luteal phase.ResultsFor women in the luteal phase, papillary dermis and subcutaneous adipose tissue were thicker (median 0.20 mm, interquartile range [IQR] 0.12-0.25 mm vs median 0.33 mm, IQR 0.25-0.35 mm; <i>p</i> < .001 and median 5.0 mm, IQR 4.3-5.5 mm vs median 5.2 mm, IQR 4.5-6.2 mm; <i>p</i> = .013, respectively) and subcutaneous adipose tissue echogenicity was higher (median 66.9 IQR 64.1-70.5 vs median 71.7, IQR 65.0-76.7; <i>p</i> = .007) in the late afternoon than in the morning. The popliteal vein velocity-time integral (VTI) was lower in the late afternoon (median 33.0 cm, IQR 27.3-40.5 cm) than in the morning (median 26.1 cm, IQR 23.5-39.6 cm; <i>p</i> = .043). A significant negative correlation was observed between VTI and echogenicity (r = -0.549, <i>p</i> = .005). These findings were reduced in women in the follicular phase, and absent in men.ConclusionLate-afternoon lower leg edema may be associated with decreased leg blood flow in women, particularly in the luteal phase.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"2683555251341395"},"PeriodicalIF":0.0,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144049502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Age-related risk factors and manifestations in deep venous thrombosis.","authors":"Bo Wu, Haoyuan Wang, Yujia Li, Jianming Sun, Lili Zhang, Haiyang Wang","doi":"10.1177/02683555251341760","DOIUrl":"https://doi.org/10.1177/02683555251341760","url":null,"abstract":"<p><p>ObjectiveThe incidence, risk factors, and clinical presentation of deep venous thrombosis (DVT) vary with age. This study aimed to evaluate the differences in clinical characteristics of DVT among patients of different ages.MethodsWe retrospectively analyzed 938 patients with symptomatic lower extremity DVT admitted to our hospital between January 2020 and January 2024. Patients were categorized into youth (<40 years), middle-aged (40-64 years), and elderly (>65 years) groups. Demographic data, comorbidities, risk factors, clinical presentations, and management approaches were collected and analyzed.ResultsMost participants were middle-aged or elderly, with young patients constituting only 11.19% of the study population. The youth group had a slight female predominance, while the middle-aged and elderly group had a balanced gender distribution. The elderly group were more likely to have comorbidities such as diabetes and malignancies, though they had a lower prevalence of autoimmune diseases compared to younger patients. Congenital risk factors were relatively rare in the overall population, yet were present in 22.86% of young patients, a significantly higher proportion than in the middle-aged and elderly groups. Most patients with DVT were provoked, especially in the elderly group. The prevalence of concurrent congenital and acquired factors was 13.33% in the youth group, compared to only 4.97% in the middle-aged group and 2.88% in the elderly group. Proximal DVT was most frequent in middle-aged patients, while young patients were more likely to seek treatment in the acute phase and undergo surgical intervention. Anticoagulation noncompliance was noted in nearly 40% of elderly patients but only 6.67% of young patients.ConclusionRisk factors and clinical characteristics of DVT vary significantly with age, particularly between young and elderly patients. Young patients were more inclined to seek prompt and effective treatment and demonstrated better adherence to anticoagulation therapy.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"2683555251341760"},"PeriodicalIF":0.0,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144061670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety and efficacy of interstitial bleomycin sclerotherapy for foam sclerosant-infeasible small solid venous malformations in the lower extremity.","authors":"Kyoung Yeon Lee, Taejun Jeon, Sang Yub Lee, Kwang Bo Park, Hong Suk Park, Dongho Hyun, Sung Ki Cho, Sung Wook Shin, Chang Hoon Oh","doi":"10.1177/02683555251339941","DOIUrl":"https://doi.org/10.1177/02683555251339941","url":null,"abstract":"<p><p>PurposeTo evaluate the safety and efficacy of interstitial bleomycin sclerotherapy for treating small painful venous malformations (VMs) in the lower extremities.MethodsBetween September 2022 and August 2024, 256 patients underwent 420 sclerotherapy sessions for slow-flow vascular malformations. Exclusions included sponge-form VMs, lymphatic malformations, fibroadipose vascular anomalies, and syndromic vascular anomalies. Thirteen patients with solid VMs in the lower extremities, unresponsive to prior foam sclerotherapy (<i>n</i> = 6) or with vascular access challenges due to the lesion's solid nature (<i>n</i> = 7), underwent 19 interstitial bleomycin sclerotherapy sessions. Pre- and post-treatment assessments included visual analog scale (VAS) scores and imaging findings for lesion diameter and vascularity.ResultsNineteen bleomycin sclerotherapy sessions were conducted in 13 patients. VMs were intramuscular (<i>n</i> = 11), in the sub-fascial fat layer (<i>n</i> = 1), or both (<i>n</i> = 1). The mean interval between prior foam and bleomycin sclerotherapy was 818 days, with a 254-day follow-up after treatment. Pain improved in 92% of patients, with a VAS score reduction from 8.5 to 2.8 (<i>p</i> = .0001). One patient showed no improvement after three sessions. Among six patients with vascularity detected on Doppler ultrasound pre-treatment, all demonstrated resolution post-treatment (<i>p</i> = .0313). Mean diameter reduction of 0.27 cm was not statistically significant (<i>p</i> = .0573). Three minor/moderate adverse events occurred: allergic reactions and skin pigmentation.ConclusionInterstitial bleomycin sclerotherapy is a safe and effective option for reducing pain and vascularity in lower extremity solid VMs unresponsive to foam sclerotherapy or presenting poor vascular access.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"2683555251339941"},"PeriodicalIF":0.0,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144016625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Superficial vein thrombosis: State of art. A review.","authors":"Francesca Cortese, Luisiana Stolfi, Giampaolo Luzi, Giandomenico Tarsia, Gianpaolo D'Addeo, Marilena De Francesco, Paolo Tondi, Marco Fabio Costantino","doi":"10.1177/02683555251338747","DOIUrl":"https://doi.org/10.1177/02683555251338747","url":null,"abstract":"<p><p>ObjectivesSuperficial venous thrombosis (SVT) is an acute thrombosis affecting the superficial venous system, characterized by inflammation of the venous wall. While much research has focused on deep vein thrombosis (DVT), SVT has historically been neglected due to its reputation as a benign and self-limiting condition.MethodsA literature search was conducted using PubMed and Google Scholar from January 2000 to December 2023, focusing on English-language publications and including original articles, systematic reviews, and randomized controlled trials. The following keywords were used in various combinations: \"superficial venous thrombosis,\" \"superficial thrombophlebitis,\" \"phlebitis,\" and \"thrombophlebitis.\" The review aimed to analyze SVT, discuss its key features, treatment approaches, and prognosis. We identified 133 potentially relevant records, of which 98 were screened in full text; 39 met our inclusion criteria (i.e., adult populations, clinical data on SVT incidence, risk factors, and treatment outcomes). A PRISMA-style flowchart illustrates the selection process and reasons for exclusion (e.g., duplication, lack of relevant endpoints).ResultsSVT is a common but often underestimated condition that can lead to complications, including pulmonary embolism. The mainstay treatment consists of anticoagulant therapy, starting with low-dose unfractionated heparin or fondaparinux as the first-line drug, progressing to oral anticoagulants at therapeutic doses in more extensive cases. The diagnosis is primarily clinical but should be confirmed by color Doppler ultrasound. Furthermore, SVT may be indicative of serious underlying conditions.ConclusionsWhile often considered benign, SVT is a deceptive pathology. If not properly diagnosed and treated, it can progress to DVT and associated complications. Additionally, SVT may signal significant systemic conditions such as malignancies, hereditary thrombophilia, and cardiovascular diseases, warranting further investigation by clinicians.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"2683555251338747"},"PeriodicalIF":0.0,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144045736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Complication rate with the 1940-nm versus 1470-nm wavelength laser.","authors":"Hak Hong Keo, Karoline Gondek, Nicolas Diehm, Christoph Leib, Heiko Uthoff, Rolf P Engelberger, Daniel Staub","doi":"10.1177/02683555241301192","DOIUrl":"10.1177/02683555241301192","url":null,"abstract":"<p><p>BackgroundWe hypothesized, that endovenous laser ablation (EVLA) with the highly water specific 1940-nm wavelength laser would reduce ablation-related thrombus extension (ARTE) incidence compared to the less specific 1470-nm laser.Materials and methodsBetween February 2017 to March 2023 we identified a consecutive series of patients undergoing EVLA from the prospectively ongoing VEINOVA registry. Patients were treated with the 1940-nm or 1470-nm laser. Demographic data and outcome data were used for this retrospective analysis.ResultsFrom a total of 3055 EVLA, 2006 procedures were performed with the1470-nm and 1049 with the 1940-nm laser. At 2-6 days follow- up visit (follow up visit 1), all ARTE occurred in 18 (0.9%) of all procedures with the 1470-nm and in 1 (0.1%) with the 1940-nm laser (<i>p</i> = 0.023). DVT was similar in both groups (0.3% vs 0.2%, <i>p</i> = 0.784). Phlebitis occurred in 67 (3.3%) of all procedures with the 1470-nm and in 2 (0.2%; <i>p</i> = 0.003) with the 1940-nm laser and paresthesia in 99 (4.9%) versus 5 (0.5%; <i>p</i> < 0.001), respectively. At 5-6 weeks follow-up (follow up visit 2), all ARTE occurred in 27 (1.4%) of all procedures with the 1470-nm and in 4 (0.4%; <i>p</i> = 0.010) with the 1940-nm laser. DVT was similar in both groups (0.7% vs 0.4%; <i>p</i> = 0.846). Phlebitis occurred in 97 (4.8%) of all procedures with the 1470-nm and in 9 (0.9%; <i>p</i> < 0.001) with the 1940-nm laser and paresthesia in 194 (9.7%) versus 35 (3.3%; <i>p</i> < 0.001), respectively. Occlusion rate was in both groups similar (99.8% vs 99.6%).ConclusionEVLA using the 1940-nm laser appears to be safe with lower ARTE incidence than using the 1470-nm laser. Phlebitis and paresthesia occurred less frequent with the 1940-nm than with the 1470-nm laser, thus favoring the use of the 1940-nm laser.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"283-291"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An open label, single-centric, post market clinical study to evaluate the safety and efficacy of a new antimicrobial wound dressing (VELVERT) as an adjuvant therapy in the treatment of venous leg ulcer.","authors":"Sudhir Kumar, Suvash Sahu, Shivam Sharma","doi":"10.1177/02683555241288729","DOIUrl":"10.1177/02683555241288729","url":null,"abstract":"<p><p>ObjectivesAn open label, single-centric, post market clinical study was undertaken to evaluate the safety and efficacy of a new antimicrobial wound dressing (VELVERT) as an adjuvant therapy in the treatment of venous leg ulcer (VLU).MethodsPatients with VLU of grade C-5 according to CEAP classification and above were evaluated using doppler ultra sound. The efficacy of new antimicrobial wound dressing (VELVERT) was assessed in terms of wound area reduction within a time frame of 60 days and surgeon questioners. Patients were evaluated for VELVERT safety and pain level on a scale of 0-10 Numeric Pain Chart. Presence of micro-organism load was monitored at regular time interval.ResultsVELVERT treatment was effective as 71.43% reduction in the ulcer area was observed. After 60 days, a total of 9 (45%) patients had complete ulcer closure. A remarkable decrease in the severity of pain was observed with 11 (55%) patients expressing no pain at the EOT. Swab test showed negative result for micro-organism growth. No serious adverse events were observed during the trial.ConclusionThe data indicates that VELVERT is an effective treatment for VLUs and showed the potential in the wound care of VLUs.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"255-265"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142396560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A surge of interest: Analysing the increased public interest in lipedema using google trends.","authors":"Yakup Erden, Mustafa Hüseyin Temel, Fatih Bağcıer","doi":"10.1177/02683555241286354","DOIUrl":"10.1177/02683555241286354","url":null,"abstract":"<p><p>AimThis study aimed to monitor public interest in information related to Lipedema and examine potential temporal, seasonal, and income-related trends that may impact public interest.Material - MethodsA dataset was created using the Google Trends tool by inputting the keyword \"Lipedema\" to obtain the relative search volume (RSV) from 2004 to the present in the United States (US). To examine potential income-related disparities in public interest in Lipedema across the US, RSV values were recorded in the five states with the highest and the lowest median income (Maryland, New Hampshire, New Jersey, Utah, and Washington and Mississippi, West Virginia, Arkansas, New Mexico, Kentucky, respectively).ResultsPublic interest in Lipedema increased significantly over time (R² = 0.693, <i>p</i> < .001 for the linear trend; R² = 0.880, <i>p</i> < .001 for the quadratic trend). There were no significant differences between the RSV values between the month of the year and the season of the year (<i>p</i> = 1.000 and <i>p</i> = .859, respectively). RSV values of the five highest-income and low-income states showed significant increases (R² = 0.333, <i>p</i> < .001, and R² = 0.195, <i>p</i> < .001, respectively) More rapid growth in interest in Lipedema in states with high income compared to the states with low income (<i>p</i> < .001).ConclusionPublic interest in Lipedema is increasing in both high-income and low-income states. States with higher incomes are more interested. Searches for lipedema are expected to become more frequent, leading to a rising demand for comprehensive education in medical schools and clinician training programs. In addition, there will also be a need for easily accessible, high-quality information resources.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"228-234"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142335873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improvement of quality of life in women ≤ 25-years-old with chronic pelvic pain following stenting of nonthrombotic iliac vein compression.","authors":"Elizabeth Brooke Spencer, Ariana Schuelke, Kyra Porter, Jacqueline Nelson, Elisabeth S Horne","doi":"10.1177/02683555241287312","DOIUrl":"10.1177/02683555241287312","url":null,"abstract":"<p><p>ObjectivesStenting of nonthrombotic iliac vein compression for chronic pelvic pain (CPP) is controversial, especially in young populations. The current study evaluated the effects of iliac vein stenting on CPP through the assessment of quality-of-life (QoL) and pain scores in female patients ≤25-year-old.MethodsA retrospective single site cohort study was conducted for 30 female patients who were treated with left common iliac vein (LCIV) stenting for CPP. QoL was assessed before and after stenting using the following assessments: International Pelvic Pain Society (IPPS), Pelvic Congestion Syndrome (PCS), Pelvic Pain and Urinary Urgency Frequency (PUF), Rome III IBS, ancillary symptoms assessment, and pain scores. Secondary evaluation of the accuracy of radiologic interpretations of iliac vein compression on CT and MRI was also performed. Finally, commonly associated comorbidities within this population were assessed.ResultsPatient reported outcomes in 30 iliac vein stent patients demonstrated improvements in QoL post-stenting as demonstrated through significant reductions in IPPS, PCS, and pain scores (<i>p</i> = .0103, .0156, and .0092, respectively). Many of the cross-sectional imaging studies that were read by the interpreting radiologist as normal or mild compression were later identified as moderate or severe by the interventional radiologist clinically evaluating the patient. These patients went on to show significant compression on venography and intravascular ultrasound with associated clinical improvement after stenting.ConclusionSignificant improvements in QoL were identified in young women with CPP after LCIV stenting. Similarities in the clinical presentation of common comorbidities and misinterpretation of cross-sectional imaging studies may make the identification of pelvic venous disease more challenging. Our findings endorse the need for further research on stenting in young women with venous origin CPP through comparative outcomes studies and blinded randomized controlled trials.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"243-254"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142378771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}