Phlebology最新文献

{"title":"Rapid noncontrast MRI screening for iliac and left renal vein compression: A practical bSSFP technique.","authors":"Abdulmalik Alruhaimi, Adam Gaisinsky, Ali Sabri, Andrew D Brown","doi":"10.1177/02683555261499774","DOIUrl":"https://doi.org/10.1177/02683555261499774","url":null,"abstract":"<p><p>ObjectivesTo describe a rapid, widely available, noncontrast magnetic resonance imaging (MRI) technique for first-line morphologic assessment of suspected iliac and left renal vein compression in patients with symptoms potentially related to pelvic venous disorders.MethodsWe use a two-stack axial two-dimensional balanced steady-state free precession (bSSFP) acquisition extending from the renal hila through the iliac bifurcation. The sequence is available on major MRI platforms as TrueFISP (Siemens), FIESTA (GE), or bTFE (Philips). Typical 1.5-T parameters are TR/TE 3.0-3.8/1.5-1.9 ms, flip angle 60-80°, 5-mm slice thickness, and 1.3-1.6-mm in-plane resolution. Localized shimming is performed for each stack.ResultsThe abbreviated examination requires approximately 10 minutes of scanner time, including planning and breath-hold acquisitions. It depicts the site and degree of iliac or left renal vein compression and demonstrates collateral pathways that may support physiologic relevance. Morphologic abnormalities are interpreted in the clinical context and are not considered diagnostic of a symptomatic syndrome in isolation.ConclusionsA short bSSFP protocol can provide a practical, radiation-free gateway examination when comprehensive MR venography is unavailable or undesirable. It may facilitate appropriate referral and procedural planning, while invasive assessment, including intravascular ultrasound when stenting is contemplated, remains necessary in selected patients.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"2683555261499774"},"PeriodicalIF":1.5,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149221238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"DSA-guided versus ultrasound-guided foam sclerotherapy for venous leg ulcers: A retrospective comparative study.","authors":"Luan Xie, Yang An, Xiaochao Liu, Tuanjie Zhang, Wensi Wu","doi":"10.1177/02683555261501416","DOIUrl":"https://doi.org/10.1177/02683555261501416","url":null,"abstract":"<p><p>ObjectiveTo compare the short-term efficacy between DSA-guided and ultrasound-guided foam sclerotherapy (UGFS) for venous leg ulcers (VLUs).MethodsWe retrospectively analyzed patients with CEAP-C6 venous ulcers of the lower extremity admitted to a tertiary hospital between January 2021 and January 2024 who completed 12 months of follow-up. A total of 45 patients were included in the ultrasound-guided foam sclerotherapy group (US group) and 35 in the DSA-guided foam sclerotherapy group (DFS group). Ulcer healing time, dynamic healing rate, complications, and recurrence rate were compared between the two groups.ResultsThe ulcer healing rates at 1 and 3 months after surgery were significantly higher in the DFS group than in the US group (80.0% vs 55.6%, <i>P</i> = 0.022; 91.4% vs 71.1%, P = 0.024). The DFS group also had a lower postoperative pain score [2 (1-3) versus 3 (2-4) <i>P</i> = 0.006]. The recurrence rate at 12 months showed a decreasing trend in the DFS group (11.4% vs 26.7%, <i>P</i> = 0.091). There were no significant differences in the incidences of superficial thrombophlebitis or pigmentation between the two groups, and the rate of skin necrosis was slightly lower in the DFS group (5.7% vs 8.9%).ConclusionCompared with ultrasound-guided foam sclerotherapy, DSA-guided foam sclerotherapy was associated with faster short-term ulcer healing, and lower postoperative pain in patients with venous leg ulcers. These preliminary findings suggest that DSA guidance may offer a potential advantage in improving the precision of sclerotherapy for lower extremity venous ulcers; however, these results require validation in prospective multicenter studies with larger sample sizes.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"2683555261501416"},"PeriodicalIF":1.5,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149225716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors affecting the longevity and quality of detergent sclerosant foams.","authors":"Richard J Oliver, Mike R Watkins","doi":"10.1177/02683555261499789","DOIUrl":"https://doi.org/10.1177/02683555261499789","url":null,"abstract":"<p><p>ObjectivesDetergent sclerosant foam quality varies between syringe brands and devices. This study examined the foam duration and quality of using multiple syringe brands, connectors and foam making devices.MethodsA range of widely available syringes, connectors and foam making devices were tested with the sclerosants sodium tetradecyl sulfate (STS) and polidocanol (POL). 1% and 3% solutions were tested because these are licensed for use as foam. The manufactured foam containing syringe was inverted and the breakdown of foam recorded with a digital video camera. The time taken for the liquid to reform according to the syringe graduations was recorded. Additionally, qualitative observations were recorded.ResultsSignificant differences between syringe brands were observed in the foam longevity for 1% STS, 3% STS and 1% POL but not for 3% POL. There were no significant differences between connectors or foam making devices. The qualitative observations revealed large bubbles and rapidly degenerating foam in some syringes even if the liquid reformation was slower.ConclusionsSyringe brand affects the longevity and quality of sclerosant foam especially with STS and 1% POL but not with 3% POL. It is inferred that the cause of the differences is due to the syringe siliconisation and the mode of sterilisation. Liquid reformation should not be the only criteria for assessment; a qualitative observation of the foam in the syringe should always be made.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"2683555261499789"},"PeriodicalIF":1.5,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149225712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Readability, reliability, and quality of AI-Generated responses on pelvic congestion syndrome: A comparative analysis of ChatGPT, gemini, and perplexity.","authors":"Emre Sertel","doi":"10.1177/02683555261499766","DOIUrl":"https://doi.org/10.1177/02683555261499766","url":null,"abstract":"<p><p>ObjectivePelvic congestion syndrome (PCS) is a vascular cause of chronic pelvic pain arising from ovarian and pelvic venous insufficiency, typically presenting as dull, aching pelvic pain that worsens with prolonged standing, physical activity, and the premenstrual period, and is particularly common among multiparous women of reproductive age. Online health information on this condition is frequently accessed by both patients and healthcare professionals. This study aimed to evaluate the readability, quality, and reliability of responses generated by three popular artificial intelligence (AI) chatbots-ChatGPT-4o, Gemini, and Perplexity-regarding the most commonly asked questions on PCS.MethodsFrom 25 PCS-related keywords identified through Google Trends, duplicates and irrelevant terms were excluded, yielding a final set of 18 keywords. These were separately submitted to the three AI chatbots. Readability was assessed using the Gunning Fog Index (GFOG), Simple Measure of Gobbledygook (SMOG), and Flesch Reading Ease Score (FRES), among other indices, calculated via two independent readability tools. Quality was measured using the Global Quality Score (GQS) and the Ensuring Quality Information for Patients (EQIP) tool, while reliability was assessed with the Journal of the American Medical Association (JAMA) benchmark criteria and the modified DISCERN instrument.ResultsReadability analyses revealed that all chatbot responses significantly exceeded the sixth-grade level recommended by the AMA and NIH (p < .001). ChatGPT-4o achieved the highest readability on the CLI and ARI, whereas Gemini performed better on the remaining indices, and Perplexity consistently produced the most complex responses. Among the three evaluated freely accessible platforms, Perplexity achieved the highest scores on several quality and reliability measures (JAMA, DISCERN, and GQS), while Gemini outperformed the others on EQIP scoring.ConclusionAlthough AI chatbots hold promise for providing accessible information on PCS, their readability levels remain above recommended standards, and overall quality scores are suboptimal. Producing clearer, more balanced, and more reliable content could enhance the contribution of these technologies to public health.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"2683555261499766"},"PeriodicalIF":1.5,"publicationDate":"2026-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149221300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physiotherapeutic resources in lipedema: A scoping review.","authors":"Bibiana Copello Rotili, Maria Rita Brandão, Cristiane Buzanello Donin, Dartel Ferrari de Lima, Gladson Ricardo Flor Bertolini, Márcia Rosângela Buzanello","doi":"10.1177/02683555261500186","DOIUrl":"https://doi.org/10.1177/02683555261500186","url":null,"abstract":"<p><p>BackgroundLipedema is a chronic condition that predominantly affects women and is commonly associated with pain, edema, and functional impairment. Conservative physiotherapy interventions are frequently recommended; however, the scope and characteristics of the available evidence remain unclear.ObjectiveTo map the existing evidence on conservative physiotherapy interventions for lipedema, focusing on intervention types, outcomes assessed, and methodological characteristics.MethodsA scoping review was conducted according to the PRISMA-ScR guidelines. Eligibility was guided by the PCC framework. Electronic databases and gray literature were searched for primary studies and secondary sources addressing conservative physiotherapy interventions for lipedema. Data were synthesized descriptively.Results15 records were included, comprising randomized controlled trials, observational studies, and secondary sources such as reviews, guidelines, and consensus documents. The most frequently investigated interventions were complex decongestive therapy, therapeutic compression, structured exercise programs, and adjunct physical modalities. Outcomes mainly included edema, pain, functional capacity, and quality of life. Among primary studies, multimodal conservative physiotherapy approaches were the most frequently reported. Secondary sources consistently described conservative physiotherapy as a component of care, although they were not treated as independent confirmation of treatment effects.ConclusionThe available literature suggests that conservative physiotherapy is frequently described as a component of lipedema management. However, the evidence base is characterized by methodological heterogeneity, small sample sizes, and the absence of formal quality appraisal, and the findings should be interpreted as a mapping of the available evidence rather than as evidence of treatment efficacy.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"2683555261500186"},"PeriodicalIF":1.5,"publicationDate":"2026-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149217865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical characteristics, risk factors, and prognosis of incidental and symptomatic hospital-acquired pulmonary embolism: A retrospective cohort study.","authors":"Peng Jiang, Jiawei Fan, Wenfei Guan, Yongpan Cui, Zihan Zhang, Jian He, Fei Mei","doi":"10.1177/02683555261499772","DOIUrl":"https://doi.org/10.1177/02683555261499772","url":null,"abstract":"<p><p>ObjectivesTo compare the clinical characteristics, risk factors, and prognosis of incidental pulmonary embolism (IPE) and symptomatic pulmonary embolism (SPE), and to inform risk-stratified management.MethodsThis retrospective study analyzed 287 patients with hospital-acquired pulmonary embolism (HA-PE). Demographic, clinical, imaging, and laboratory data were collected. Survival outcomes were assessed using Cox regression and Kaplan-Meier analyses.ResultsAmong 287 patients, 87 had IPE and 200 had SPE. IPE was more frequently classified as low-risk PE (63.22% vs. 31.50%, <i>p</i> < 0.001) and more often involved pulmonary artery branches (73.56% vs. 58.00%, <i>p</i> = 0.01), whereas SPE was more commonly intermediate- or high-risk. The 1-month survival rate was higher in the IPE group than in the SPE group (95.4% vs. 75.5%, hazard ratio [HR]: 5.95, 95% confidence interval [CI]: 2.51 - 16.5, <i>p</i> < 0.001), but this difference was not significant after 1 month. In IPE, cancer and bleeding were associated with increased mortality, whereas anticoagulation and lower PE risk categories were associated with reduced mortality. In SPE, cancer and immobilization were associated with increased mortality, whereas anticoagulation, thrombectomy, and lower PE risk categories were associated with reduced mortality.ConclusionsIPE is generally associated with lower-risk, more peripheral PE, but anticoagulation should be individualized. SPE requires prompt risk stratification and timely anticoagulation, with reperfusion or thrombectomy considered for selected high-risk or deteriorating patients.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"2683555261499772"},"PeriodicalIF":1.5,"publicationDate":"2026-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149217836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sex differences and prevalence of prior deep vein thrombosis among patients with incidental iliac vein compression on computed tomography.","authors":"Zohaib Y Lakhani, Christopher J Reisenauer, Forrest B Linch, Richard G Frimpong, Matthew R Augustine, Edwin A Takahashi","doi":"10.1177/02683555261499780","DOIUrl":"https://doi.org/10.1177/02683555261499780","url":null,"abstract":"<p><p>PurposeThe purpose of this study was to identify risk factors and evaluate clinical outcomes associated with incidental left common iliac vein compression on CT imaging.MethodsThis is a retrospective study that reviewed venous-phase abdomen and pelvis CT scans to identify patients with incidental extrinsic compression of the left common iliac vein due to an overlying right common iliac artery. A total of 726 patients were included (364 females, 362 males; mean patient age: 61.9 ± 15.9 years). Board-certified radiologists reviewed all CT scans. Significant left iliac vein compression was defined as >50% luminal narrowing.ResultsSignificant iliac vein compression was identified in 114 (15.7%) patients and was more common in females (19.5%) versus males (11.9%) (<i>p</i> < 0.01). Patients with iliac vein compression >50% had significantly lower BMI than those without compression (24.8 ± 6.2 vs 28.7 ± 7.2 kg/m², <i>p</i> < 0.01). Patients with incidental left iliac vein compression had a higher rate of prior left lower extremity DVT (<i>p</i> = 0.02).ConclusionIncidental left common iliac vein compression was present in approximately 16% of patients and was more frequent among females. Compression was associated with lower BMI and more than twice the rate of ipsilateral DVT, despite no prior diagnosis of MTS. These findings suggest that incidental iliac vein compression could have more clinical significance than previously recognized.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"2683555261499780"},"PeriodicalIF":1.5,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149198408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical and ultrasonographic effects of extracorporeal shock wave therapy in patients with lipedema: A prospective study.","authors":"Elif Özyiğit, Dilek Ün Oğuzhanasıltürk, Ömer Özyiğit, Mert Zure","doi":"10.1177/02683555261499797","DOIUrl":"https://doi.org/10.1177/02683555261499797","url":null,"abstract":"<p><p>ObjectivesTo investigate the clinical and ultrasonographic changes associated with radial extracorporeal shock wave therapy (rESWT) in women with lipedema.MethodsThis prospective, single-arm study included 40 women with lipedema who completed six sessions of rESWT administered twice weekly to the index lower limb. Treatment consisted of 3000-6000 impulses at 15 Hz and 3-4 bar. Participants were evaluated at baseline (T0), immediately after treatment (T1), and at 4-week follow-up (T2). Outcomes included visual analog scale (VAS) pain scores, Patient-Reported Outcomes Measurement Information System (PROMIS) scores, pressure pain threshold (PPT), limb circumference, subcutaneous fat thickness (SCFT), and tissue echogenicity. Patient Global Impression of Change (PGIC) was assessed at T1 and T2.ResultsVAS scores decreased from 8.45 at T0 to 5.45 at T1 and 4.17 at T2, while PROMIS scores decreased from 25.3 to 16.2 and 14.3, respectively (both <i>p</i> < .001). PPT increased significantly at all four evaluated sites (<i>p</i> < .001). Calf and thigh circumferences decreased significantly over time (both <i>p</i> < .001). Medial calf SCFT decreased from 16.5 to 15.2 and 15.1 mm, and medial thigh SCFT from 21.0 to 18.2 and 18.1 mm (both <i>p</i> < .001). Median tissue echogenicity decreased from 3 at baseline to 2 at both post-treatment assessments (<i>p</i> < .001). PGIC scores also improved between T1 and T2 (<i>p</i> < .001).ConclusionsSix sessions of rESWT were associated with improvements in pain, quality of life, mechanical pain sensitivity, limb circumference, and ultrasonographic tissue characteristics in women with lipedema, with most improvements maintained at 4-week follow-up. These findings support further evaluation of rESWT as an adjunctive conservative treatment for lipedema in controlled studies with longer follow-up.Trial registrationClinicalTrials.gov, NCT07683559.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"2683555261499797"},"PeriodicalIF":1.5,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149208434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sensitization-related pain phenotypes and their clinical correlates in women with lipedema: A case-control study.","authors":"Esra Şahingöz Bakırcı, Gülseren Demir Karakılıç","doi":"10.1177/02683555261499769","DOIUrl":"https://doi.org/10.1177/02683555261499769","url":null,"abstract":"<p><p>ObjectivesLipedema is a chronic adipose tissue disorder characterized by disproportionate fat accumulation, lower extremity pain, functional impairment, and reduced quality of life. Although pain is a cardinal symptom, its underlying mechanisms remain incompletely understood. This study aimed to characterize sensitization-related pain phenotypes in women with lipedema by examining central sensitization (CS) and neuropathic -like pain features and their associations with lower extremity function, sleep quality, and health-related quality of life (HRQoL).MethodsIn this cross-sectional case-control study, 54 women with clinically diagnosed lipedema and 48 age-matched control participants were enrolled between March and October 2025. Pain phenotypes were assessed using the Central Sensitization Inventory (CSI) and Pain-DETECT questionnaire. Lower extremity function, sleep quality, and HRQoL were evaluated using Lower Extremity Functional Scale (LEFS), Jenkins Sleep Scale (JSS), and EuroQol-5D-3L (EQ-5D-3L), respectively.ResultsWomen with lipedema had significantly higher Pain-DETECT and CSI scores than controls, indicating greater neuropathic-like pain features and CS-related symptom burden (both <i>p</i> < .01). They also demonstrated poorer lower extremity function, greater sleep disturbance, and lower HRQoL. Pain-DETECT scores were positively correlated with CSI, anxiety, depression, and sleep disturbance scores. In multivariable analyses, LEFS independently predicted Pain-DETECT scores (B = -0.171, <i>p</i> = .015), whereas anxiety independently predicted CSI scores (B = 1.980, <i>p</i> = .002).ConclusionsWomen with lipedema exhibit prominent sensitization-related pain phenotypes associated with functional impairment, sleep disturbances, and reduced quality of life. Identification of these pain characteristics may improve clinical assessment, patient stratification, and multidisciplinary management of lower extremity symptoms in lipedema.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"2683555261499769"},"PeriodicalIF":1.5,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149208433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship between sleep quality and pain, fatigue, and mood in individuals with lipedema.","authors":"Nur Kesiktaş, Sedef Ersoy, Büşra Şirin Ahısha","doi":"10.1177/02683555261499144","DOIUrl":"https://doi.org/10.1177/02683555261499144","url":null,"abstract":"<p><p>ObjectiveThis study aimed to comparatively evaluate sleep quality in individuals with lipedema and healthy controls. In addition, the relationships between sleep quality and depression, anxiety, fatigue, and clinical parameters were investigated.MethodsThis cross-sectional study included 30 women with lipedema and 30 healthy female controls aged 18-75 years. Pain severity in individuals with lipedema was assessed using the Visual Analog Scale (VAS). Lipedema stage, comorbidities, and symptom duration were also recorded. Sleep quality was evaluated using the Pittsburgh Sleep Quality Index (PSQI), depressive and anxiety-related symptoms were assessed using the Beck Depression Inventory (BDI) and Beck Anxiety Inventory (BAI), and fatigue severity was evaluated using the Fatigue Severity Scale (FSS).ResultsIndividuals with lipedema had significantly higher BDI, BAI, and FSS scores than controls (all <i>p</i> < 0.001 except BDI, <i>p</i> = 0.001). Sleep quality was significantly poorer in the lipedema group (<i>p</i> < 0.001). Among PSQI subcomponents, subjective sleep quality, sleep latency, sleep duration, habitual sleep efficiency, sleep disturbances, and daytime dysfunction were significantly worse in individuals with lipedema, while sleep medication use was similar between groups (<i>p</i> > 0.05). In the lipedema group, PSQI scores were positively correlated with depressive (r = 0.489, <i>p</i> = 0.006) and anxiety symptoms (r = 0.386, <i>p</i> = 0.035). No significant associations were found between sleep quality and age, anthropometric measurements, education duration, pain severity, lipedema stage, symptom duration, or fatigue severity.ConclusionsThis study demonstrated poorer sleep quality in individuals with lipedema compared to healthy controls. Sleep quality was also associated with depressive and anxiety-related symptoms, highlighting an association between psychological symptoms and sleep problems in individuals with lipedema.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"2683555261499144"},"PeriodicalIF":1.5,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149198642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}