Phlebology最新文献

{"title":"Lipedema awareness and knowledge level among medical doctors in Turkey: A cross-sectional study highlighting the diagnosis and treatment gap.","authors":"Nazire Bagatir, Cigdem Cinar, Aysun Akansel, Mucahit Atasoy, Omer Faruk Bucak, Pinar Oztop, Evrim Coskun","doi":"10.1177/02683555251332998","DOIUrl":"10.1177/02683555251332998","url":null,"abstract":"<p><p>IntroductionLipedema is a chronic and progressive adipose tissue disorder that predominantly affects women. However, despite its high prevalence and severe negative impact on quality of life, it remains significantly underdiagnosed. The aim of this study was to assess the knowledge and awareness of medical doctors in Turkey regarding lipedema.MethodsA cross-sectional study was conducted among 508 medical doctors working in different clinical specialties in Turkey. A questionnaire was designed and validated by a panel of physical medicine and rehabilitation specialists. A total of 22 questions were asked to assess physicians' age, specialty, clinical experience, and institutional characteristics, as well as their knowledge of the clinical features, diagnostic criteria, and treatment modalities of lipedema.Results47.6% of the physicians were between 31 and 40 years of age. 29.3% of the participants had been practicing medicine for 0-5 years. 51% were familiar with the term \"lipedema\", but only 29.9% had seen or referred patients with lipedema. 51.4% of the participants answered \"no idea\" when asked about the lipoedema clinic and 50.9% answered \"no idea\" when asked about lipoedema treatment.ConclusionThis study identifies significant gaps in medical professionals' knowledge and awareness of lipedema in Turkey. The findings emphasize the necessity to incorporate lipedema-specific content in medical education and continuing professional development programs. Moreover, the establishment of multidisciplinary models of care, the dissemination of standardized clinical guidelines, and the promotion of public awareness campaigns are imperative to enhance early recognition and effective management of lipedema, which is often overlooked.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"680-688"},"PeriodicalIF":1.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143775184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deciphering the association between gut microbiome and varicose veins: A mendelian randomization study.","authors":"Yu Tian, Furong Hao, Jiantao Zhang, Yuxuan Qian, Jiahao Liu, Qianhui Bao, Haipeng Shi, Tianjie Li, Tao Yang","doi":"10.1177/02683555251329406","DOIUrl":"10.1177/02683555251329406","url":null,"abstract":"<p><p><b>Background:</b> Despite the well-documented influence of traditional risk factors on varicose veins, the potential causal role of the gut microbiome in this condition remains underexplored. This study aims to elucidate the association between specific gut microbial taxa and varicose veins using a Mendelian Randomization (MR) approach. <b>Methods:</b> Utilizing genome-wide association study datasets from the MiBioGen Consortium and the Finnish database, this study carefully selected instrumental variables based on their genetic association with the gut microbiome and stringent statistical criteria. Multiple MR techniques were applied to analyze the data, accompanied by comprehensive sensitivity analyses to ensure the reliability of the causal relationships between the gut microbiota and varicose veins. <b>Results:</b> The study identified three microbial taxa-genus <i>Terrisporobacter</i>, <i>Coprococcus2</i>, and <i>Ruminococcus</i> gnavus group-as protective factors against varicose veins. Conversely, the family Ruminococcaceae, genus <i>Flavonifractor</i>, and genus <i>Ruminococcaceae</i>UCG009 were associated with an increased risk of developing varicose veins. Bidirectional analyses indicated that the presence of varicose veins does not influence the abundance of these microbiota groups. <b>Conclusion:</b> The results of this study support a relationship between specific gut microbiota and varicose veins, revealing potential new targets for therapeutic intervention. These insights not only deepen our understanding of the pathophysiology of varicose veins but also provide a theoretical basis for future medical applications, highlighting the potential value of microbiome research in the prevention and treatment strategies for varicose veins.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"662-672"},"PeriodicalIF":1.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143736324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dynamic duplex ultrasound for the evaluation of venous circulation in the lower limbs: A pilot study using a portable device.","authors":"Luca Palombi, Monica Morelli, Erika Mendoza","doi":"10.1177/02683555251386701","DOIUrl":"https://doi.org/10.1177/02683555251386701","url":null,"abstract":"<p><p>IntroductionVenous color Doppler ultrasound, it is the gold standard for diagnosing venous insufficiency and deep vein thrombosis (DVT), guiding therapeutic decisions, and monitoring post-treatment outcomes. This article explores the indications, methodology, clinical relevance, and interpretation of a new modality of execution of DUS: the dynamic test.Materials and MethodsFive adult volunteers with confirmed CVD CEAP class C0s were enrolled after informed consent. A portable wireless ultrasound probe with B-mode, color and pulsed Doppler capabilities was used. The probe was mounted on the patient's lower limb using a dedicated support harness, which provided stable probe positioning without restricting limb mobility. The probe was placed over the small saphenous vein (SSV) in the proximal of the leg in the posterior region, just below the popliteal fossa. The examination was conducted while the patient was walking.ResultsIn one patient, a variation in the diameter of the SSV could be observed at the end of the test. In all cases, it was possible to observe a lower amplitude (msec) of the systolic peak (SP) during walking, if compared with that obtained after calf compression maneuvers. There were no differences in the systolic velocity peak between the examination conducted with activation maneuvers and the dynamic one. Reflux during dynamic movement was detected in 2/5 patients (40%) in the SSV that was not observed in static assessments.ConclusionsDynamic color Doppler ultrasound (D-DUS) using a portable probe enables real-time assessment of lower limb venous flow during physiological motion. This approach may reveal pathological reflux not evident in static examinations, offering a valuable addition to conventional venous diagnostics.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"2683555251386701"},"PeriodicalIF":1.5,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145202688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility and safety of right subclavian vein as an alternative route for retrieval of temporary inferior vena cava filters.","authors":"Tao Peng, Dan Li, Ke-Tong Wu, Yang Liu, Hai-Yang Lai, Yuan Wan, Bo Zhang","doi":"10.1177/02683555251380913","DOIUrl":"https://doi.org/10.1177/02683555251380913","url":null,"abstract":"<p><p>ObjectiveIn patients with occlusion or severe stenosis of the internal jugular vein, the retrieval of temporary inferior vena cava (IVC) filters often proves technically challenging. This study was designed to evaluate the feasibility and safety of the right subclavian vein (SCV) as an alternative access route for retrieving temporary IVC filters.MethodsPatients treated with inferior vena cava (IVC) filters were included in a retrospective analysis between August 2023 and May 2025. A total of 87 eligible patients were divided into two separate groups based on the puncture route; right subclavian vein (SCV) group and internal jugular vein (IJV) group. A retrospective analysis was performed on their patient demographics, operative duration, radiation dose, costs, and postoperative recovery time.ResultsNotable statistical disparities were detected between the two groups in primary disease, operative time, fluoroscopy time, and radiation dose. Compared with the internal jugular vein (IJV) group, the right subclavian vein (SCV) group exhibited a higher prevalence of primary malignant diseases, along with a mean 7.35-min increase in operative time, 127-s longer fluoroscopy time, and 14.11-mGy higher radiation dose. Follow-up CT assessments revealed sustained patency of the subclavian veins in the right subclavian vein (SCV) group, with no instances of thrombosis or stenosis observed during the postoperative period, or any life-threatening pneumothorax or bleeding was detected.ConclusionsThe right subclavian vein (SCV) approach is suggested as a safe and effective alternative, especially when the internal jugular vein (IJV) is severely stenosed or occluded. For temporary inferior vena cava (IVC) filter retrieval, the conventional internal jugular vein (IJV) route is recommended; however, the right subclavian vein (SCV) may be considered a clinically appropriate alternative in specific indications, without significantly increasing procedural difficulty or surgical costs.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"2683555251380913"},"PeriodicalIF":1.5,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145082886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of recurrent varicose veins: Redo open surgery versus endovascular approaches.","authors":"Vincenzo Ardita, Nicola Galati, Sarah Tinaglia, Carlo Campesi, Elena Miglioranza, Roberto Chiesa, Domenico Baccellieri","doi":"10.1177/02683555251353002","DOIUrl":"https://doi.org/10.1177/02683555251353002","url":null,"abstract":"<p><p>ObjectiveRecurrent varicose veins (RVVs) following open surgical procedures are common and present significant treatment challenges. Redo open surgery (rOS) presents risks leading to a need for alternative treatment options. This study compares the safety and efficacy of ultrasound-guided foam sclerotherapy (UGFS), used to treat recurrent reflux and remove neovascular and tributary venous networks in the thigh, to redo open surgery (rOS) for the treatment of C2r.Materials and methodsA retrospective review was conducted on 133 patients with symptomatic C2r treated between 2018 and 2020. Of these, 91 patients received UGFS-based mini-invasive treatment (Group A), and 42 underwent rOS (Group B). Data were collected during perioperative, intraoperative, and postoperative times. Clinical outcomes were assessed using the CEAP and rVCSS scoring systems. Follow-up occurred within 1 week, at 1-6 months, and annually thereafter.ResultsUGFS showed a significantly shorter average procedure time (21 ± 7 minutes) compared to rOS (47 ± 13 minutes, <i>p</i> < .001) and time spent in the hospital (3 ± 0.5 hours vs 16 ± 2 hours, <i>p</i> < .001). Both groups achieved high technical success rates. The anterior saphenous vein (ASV) was found to be incompetent in 32 patients (24%). In Group A, it was treated with radiofrequency ablation (RFA) in 10 cases and with foam sclerotherapy in 11. In contrast, all ASV cases in Group B were managed with surgical stripping. UGFS patients experienced a more rapid clinical improvement within the first-week post-treatment (<i>p</i> < .001). The freedom from recurrences was 88.9% in the Group A, and 87.8% in the Group B at 3-year (<i>p</i> = .85). The freedom from reintervention was 90.9% in the Group A, and 88.5% in the Group B at 3-year (<i>p</i> = .89).ConclusionsUGFS is a safe and effective alternative to rOS for treating C2r, offering significant advantages in shorter procedure times, faster recovery, and similar medium-term outcomes. This approach provides a viable option for C2r patients seeking effective treatment with reduced recovery periods.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"2683555251353002"},"PeriodicalIF":1.5,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145034973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and safety of short-term rivaroxaban prophylaxis after radiofrequency ablation for varicose veins: A single-centre randomised controlled trial.","authors":"Tingshuai Zhang, Xiaochuan Ge, Peiqiang Ye, Zhendong Yuan, Yunbin Zhong, Zhipeng Huang, Ni Yan, Geng Luo","doi":"10.1177/02683555251343150","DOIUrl":"https://doi.org/10.1177/02683555251343150","url":null,"abstract":"<p><p>ObjectiveLower extremity varicose veins are a common chronic venous disorder, affecting approximately 23% of adults globally. Although endovenous thermal ablation, particularly radiofrequency ablation (RFA), has become the preferred treatment, post-procedural deep vein thrombosis (DVT) remains a concern. The necessity of pharmacologic prophylaxis following RFA remains controversial. This study aimed to assess the efficacy and safety of short-term prophylactic rivaroxaban for DVT prevention after RFA.MethodsIn this single-centre, randomized controlled trial, patients with lower extremity varicose veins undergoing RFA, with or without Trivex-assisted phlebectomy, were recruited between August 2020 and December 2024. Participants were randomized to receive either rivaroxaban (10 mg daily for 5 days postoperatively) or standard preventive care including early ambulation and compression. All patients were followed for 1 month, with DVT incidence evaluated by B-mode ultrasonography.ResultsA total of 298 patients were enrolled. No DVT events occurred in the rivaroxaban group, while four cases (2.7%) were observed in the standard care group (<i>p</i> = .04). No major bleeding events were reported. Minor bleeding occurred in 4.7% of the rivaroxaban group and 2.7% of the control group (<i>p</i> = .35).ConclusionsShort-term prophylactic rivaroxaban significantly reduced DVT risk following RFA, with no significant increase in bleeding complications. These findings support its potential role in optimising perioperative thromboprophylaxis for varicose vein patients undergoing thermal ablation.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"2683555251343150"},"PeriodicalIF":1.5,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145031561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transdermal radiofrequency (V ERASER®) plus polidocanol sclerotherapy <i>versus</i> polidocanol sclerotherapy alone for the treatment of reticular veins and telangiectasias. A randomized controlled trial (TYPER trial).","authors":"Rebeca Higino Becker, Roberto Augusto Caffaro, Caroline Cândida Carvalho de Oliveira, Rafaela Palermo Marcondes, Ariadne Ribeiro Negrão, Flávia Magella, Giuliano Giova Volpiani, Samantha Neves, Renata Camila Barros Rodrigues, Mariana Ferreira Borges Firmo Rodrigues, Viviane Santana da Silva, Camilla Moreira Ribeiro, Rodrigo Kikuchi, Fabricio Rodrigues Santiago, Eduardo Ramacciotti","doi":"10.1177/02683555251375384","DOIUrl":"https://doi.org/10.1177/02683555251375384","url":null,"abstract":"<p><p>BackgroundSclerotherapy with polidocanol is the gold standard treatment for telangiectasias and varicose veins, but technologies such as transdermal radiofrequency are also available. Transdermal radiofrequency (V Eraser^®), a device that combines transdermal radiofrequency and sclerotherapy, was developed to treat these conditions.MethodsThis was a prospective, randomized, and comparative study between transdermal radiofrequency and sclerotherapy for treating telangiectasias and reticular veins. Forty-one patients were randomized to either transdermal radiofrequency plus polidocanol sclerotherapy or polidocanol sclerotherapy alone and underwent a single treatment session. Efficacy was assessed using vessel clearance analysis in pre- and post-treatment images and the Aberdeen Varicose Vein Questionnaire.ResultsForty-six patients were enrolled. Both treatments significantly reduced vessel length in a single session (<i>p</i> < .001). Sclerotherapy showed an average reduction of 30.7%, while transdermal radiofrequency reduced it by 33%, with no statistically significant difference (<i>p</i> = .596). Quality of life improved, with pain reduction in 40% and 55% of patients in the right and left lower limbs, respectively (<i>p</i> = .030 and <i>p</i> = .002).ConclusionTransdermal radiofrequency was not superior to standard of care polidocanol sclerotherapy. Both methods improved quality of life, particularly in reducing pain associated with varicose veins.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"2683555251375384"},"PeriodicalIF":1.5,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144994900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"What we cannot miss in clinical trials on compression therapy.","authors":"Giovanni Mosti, Serge Bohbot, Christine Bongards, J P Benigni, Nele Devoogdt, Isabel Forner-Cordero, Sergio Gianesini, Ravul Jindal, Fedor Lurie, Eduardo da Matta, Makoto Mo, Didier Rastel, Claas Roes, Wassila Taha, Sarah Thomis, Cees Wittens","doi":"10.1177/02683555251377228","DOIUrl":"https://doi.org/10.1177/02683555251377228","url":null,"abstract":"<p><p>BackgroundCompression therapy (CT) is widely prescribed for chronic venous disease (CVD), lymphedema, and lipedema despite robust evidence supporting its effectiveness only in a minority of clinical scenarios.AimProvide an overview of the methodological parameters essential for obtaining a high-quality scientific trial.MethodsThe International Compression Club (ICC) chairman prepared a preliminary list of the main methodological flaws in publications on CT, and a list of parameters to be included in high-quality randomized controlled trials (RCTs). This list was circulated among ICC board members, who provided their comments and suggestions. The document was then presented and discussed at an ICC consensus meeting with various professionals in May 2024 in London. Meeting minutes were distributed to ICC members, and the final document reflecting all additional comments and suggestions was compiled. In summary, the following recommendations represent the consensus of the ICC members.ResultsThe ICC recommends that the following parameters be reported in randomized clinical trials (RCTs): appropriate patient selection, adequate sample size, detailed classification of venous and lymphatic diseases, detailed description of CT modality, adherence to CT, and reasons for non-adherence. Tailored recommendations for specific scenarios and the use of standardized quality-of-life (QoL) tools are emphasized. Despite their value, RCTs face limitations and do not reflect real-world clinical practice. Real-world evidence (RWE) can complement RCTs by providing insights into routine applications, safety, compliance, and cost-effectiveness across diverse patient populations by standardized methodologies, large cohorts, and reliable validated registries to ensure validity.ConclusionsCombining data from RCTs and RWS allows for a comprehensive understanding of CT. RCTs provide evidence of effectiveness in a controlled scenario, while RWE offers real-world perspectives on compliance and economic outcomes in clinical practice. Together, these approaches enable a more holistic evaluation of CT, addressing current gaps in knowledge and guiding its optimal use.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"2683555251377228"},"PeriodicalIF":1.5,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is the weight-bearing lunge test a better tool for assessing ankle mobility in chronic venous insufficiency? A reliability and validity study.","authors":"Iane Renata Carvalhais Mesquita, Yasmmin França Eliziário, Sofia Fróis Fernandes de Oliveira, Vivian Camargo Chaves, Gustavo Reis Maciel, Dalyla Silva Lemos de Souza, Marina Silva Reis, Matheus Ribeiro Ávila, Lucas Frois Fernandes de Oliveira, Whesley Tanor Silva, Keity Lamary Souza Silva, Ana Cristina Rodrigues Lacerda, Vanessa Amaral Mendonça, Pedro Henrique Scheidt Figueiredo, Renato Guilherme Trede Filho, Vinícius Cunha Oliveira, Henrique Silveira Costa","doi":"10.1177/02683555251377308","DOIUrl":"10.1177/02683555251377308","url":null,"abstract":"<p><p>ObjectivesPatients with chronic venous insufficiency (CVI) often present with limited mobility, which can lead to pain, edema, and reduced ankle range of motion (ROM). The aim of the present study was to compare the inter-rater reliability and construct validity of the Weight-Bearing Lunge Test (WBLT) and traditional goniometry in assessing ankle dorsiflexion ROM in individuals with CVI.MethodsA cross-sectional study was conducted with 54 patients with CVI (66 ± 11 years; CEAP 1 to 6). Ankle dorsiflexion was assessed by two independent evaluators using goniometry and the WBLT. Functional performance was evaluated using the 5-repetition Sit-to-Stand Test (STS5) for strength, the 60-s Sit-to-Stand Test (STS60) for endurance, the Heel Rise Test (HRT) for calf muscle endurance, the Human Activity Profile (HAP) for activity level, and calf circumference. Inter-examiner reliability was determined using the Intraclass Correlation Coefficient (ICC), and validity was assessed through correlations between WBLT, goniometry, and functional variables.ResultsGoniometry demonstrated good inter-examiner reliability (ICC = 0.77), while WBLT showed excellent reliability (ICC = 0.98). WBLT correlated significantly with goniometry (r = -0.320; <i>p</i> = .020), HAP (r = 0.563), HRT (r = 0.378), STS5 (r = -0.605), and STS60 (r = 0.550) (all <i>p</i> < .001), whereas goniometry did not correlate with any functional outcomes.ConclusionsThe WBLT demonstrated superior inter-examiner reliability and more substantial validity compared to goniometry, supporting its use as a reliable and clinically relevant tool for assessing dorsiflexion ROM in patients with CVI.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"2683555251377308"},"PeriodicalIF":1.5,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence, risk factors, and clinical characteristics of deep vein thrombosis following combined radiofrequency ablation and sclerotherapy for varicose veins.","authors":"Bo Wu, Haoyuan Wang, Yujia Li, Jianming Sun, Haiyang Wang, Haiyan Yan","doi":"10.1177/02683555251376050","DOIUrl":"https://doi.org/10.1177/02683555251376050","url":null,"abstract":"<p><p>ObjectiveThis study aims to investigate the incidence, risk factors, and clinical characteristics of deep vein thrombosis (DVT) following radiofrequency ablation (RFA) combined with sclerotherapy for varicose veins.MethodsA retrospective analysis was conducted on patients who underwent combined RFA and sclerotherapy between June 2018 and June 2024. The incidence of postoperative DVT and its clinical characteristics were evaluated, with 13 potential risk factors assessed through univariate and multivariate logistic regression. Patients with distal DVT were divided into two groups: Group A (treatment with prophylactic-dose anticoagulation) and Group B (no anticoagulation), with thrombus resolution outcomes compared between the groups.ResultsAmong 567 patients with varicose veins, including 226 males and 341 females (male-to-female ratio 1:1.51), with a mean age of 57.79 ± 11.38 years (range: 28-77 years), postoperative DVT occurred in 46 patients (8.11%), 36 of whom (78.26%) were diagnosed within 3 days. Thrombosis predominantly affected the muscular veins and posterior tibial veins (91.30%). Multivariate analysis identified a history of thrombosis, injection volume >10 mL of foam, and injection sites distal to the ankle joint as independent risk factors for DVT. Furthermore, Group A demonstrated a significantly lower prevalence of thrombosis at each time point compared to Group B (<i>p</i> < .05).ConclusionThe incidence of postoperative DVT following combined RFA and foam sclerotherapy for varicose veins is relatively high, with the majority occurring in the early postoperative period. Thrombosis primarily affects the muscular and posterior tibial veins. A history of thrombosis, injection volume >10 mL of foam, and injection sites distal to the ankle joint are independent risk factors. Prophylactic-dose anticoagulation therapy may facilitate thrombus resolution in patients with distal DVT.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"2683555251376050"},"PeriodicalIF":1.5,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144985035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}