Phlebology最新文献_第2页

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Phlebology Pub Date : 2025-04-01 Epub Date: 2025-02-11 DOI: 10.1177/02683555251317083

引用次数: 0

Which dose of calcium dobesilate is more effective and safe in chronic venous insufficiency? Multicenter retrospective clinical trial. 哪种剂量的多贝西酸钙对慢性静脉功能不全更有效、更安全？多中心回顾性临床试验。

Phlebology Pub Date : 2025-04-01 Epub Date: 2024-09-19 DOI: 10.1177/02683555241286367

Oguz Arslanturk, Barıs Uymaz, Fatih Gumus

{"title":"Which dose of calcium dobesilate is more effective and safe in chronic venous insufficiency? Multicenter retrospective clinical trial.","authors":"Oguz Arslanturk, Barıs Uymaz, Fatih Gumus","doi":"10.1177/02683555241286367","DOIUrl":"10.1177/02683555241286367","url":null,"abstract":"ObjectivesThis study aimed to evaluate the effectiveness and safety of different dosages of calcium dobesilate in the management of Chronic Venous Insufficiency (CVI) among patients in CEAP classes C3-C4.MethodsA comprehensive multicenter retrospective analysis was conducted, including patients aged 18-70 with CEAP class C3-C4 CVI. Participants were divided into two groups: one receiving 500 mg of calcium dobesilate twice daily and the other 1000 mg twice daily. Patient progress was monitored using the Global Index Score, CIVIC-20 Score, and precise measurements of ankle and calf circumferences over a 12-month period.ResultsThe higher dosage group (1000 mg twice daily) showed significant improvements in both symptom relief and edema reduction. Ankle circumference reduced notably at 6 months, while calf circumference and overall quality of life, measured by the Global Index Score, showed significant improvement by 12 months compared to the lower dosage group.ConclusionsHigher doses of calcium dobesilate markedly enhance the management of CVI symptoms and reduce edema more effectively than lower doses, particularly in patients with advanced CVI. These findings support the use of higher dosages for optimal treatment, though further research is needed to fully evaluate long-term safety.","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"167-173"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142305469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Current state of education in venous diseases within vascular surgery training programs in Italy: A national web-based survey among residents. 意大利血管外科培训项目中的静脉疾病教育现状：一项针对住院医师的全国性网络调查。

Phlebology Pub Date : 2025-04-01 Epub Date: 2024-09-21 DOI: 10.1177/02683555241285526

Daniele Bissacco, Chiara Pisani, Paolo Verlato, Edoardo Forcella, Tiziana Aprea, Giulia Baldazzi, Ailin Belloni, Vanessa Di Mauro, Giuseppe Giuffrè, Marianna Mucignat, Michele Greco

{"title":"Current state of education in venous diseases within vascular surgery training programs in Italy: A national web-based survey among residents.","authors":"Daniele Bissacco, Chiara Pisani, Paolo Verlato, Edoardo Forcella, Tiziana Aprea, Giulia Baldazzi, Ailin Belloni, Vanessa Di Mauro, Giuseppe Giuffrè, Marianna Mucignat, Michele Greco","doi":"10.1177/02683555241285526","DOIUrl":"10.1177/02683555241285526","url":null,"abstract":"BackgroundTo analyze the perception of vascular surgery trainees from Italian schools of Vascular Surgery regarding the level of practical and theoretical education in venous diseases.MethodsAn anonymous electronic survey was sent to Italian vascular surgery residents affiliated with 19 universities, asking about their training and experience in the management of venous diseases. The survey gathered information on the residents' personal and demographic details, their university's teaching program, operative experience in phlebology, as well as their confidence levels in performing various venous procedures, with the goal of analyzing the training and learning programs provided by Italian vascular surgery schools.ResultsThe analysis showed that 28% of programs do not include phlebology in the curriculum, and more than 40% of residents are unable to independently perform venous duplex ultrasound or treat venous ulcers. Additionally, most residents (over 70%) have limited weekly exposure to phlebology cases, with only 5% having access to a dedicated phlebology operating room. The vast majority of residents (96%) expressed a strong desire to deepen their knowledge and skills in this field, particularly in areas such as endovascular ablation techniques, venous duplex ultrasound, and management of deep venous disease.ConclusionsThe survey reveals significant limitations in phlebology education and hands-on experience within the current training programs, highlighting the need to standardize and enhance venous disease management education in order to ensure that future vascular surgeons are adequately equipped to provide high-quality care for patients with a wide range of venous disorders.","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"174-181"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142305468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Can internal cooling radiofrequency catheters with local hypothermia eliminate the need for tumescent anesthesia? A single-center, retrospective, observational study. 内冷却射频导管与局部低温疗法能否消除对肿胀麻醉的需求？一项单中心、回顾性、观察性研究。

Phlebology Pub Date : 2025-04-01 Epub Date: 2024-09-27 DOI: 10.1177/02683555241287074

Gongmin Rim, Kwanyong Hyun, Deog Gon Cho, Jaemin Cho

{"title":"Can internal cooling radiofrequency catheters with local hypothermia eliminate the need for tumescent anesthesia? A single-center, retrospective, observational study.","authors":"Gongmin Rim, Kwanyong Hyun, Deog Gon Cho, Jaemin Cho","doi":"10.1177/02683555241287074","DOIUrl":"10.1177/02683555241287074","url":null,"abstract":"Background: Tumescent anesthesia not only prolongs the operation time but also induces postoperative pain, bruising, and swelling. This study investigated the effectiveness and safety of tumescentless RFA using an internal cooling system with a VENISTAR catheter and local hypothermia. Methods: We retrospectively analyzed patients who had undergone RFA for above-knee (AK) great saphenous vein (GSV) between March 2023 and November 2023. We compared the efficacy and safety of tumescentless RFA between group T (conventional tumescent group, n = 50) and group N (non-tumescent group, n = 59). Results: The operative time was shorter in group N than in group T (group N: 31.37 min, group T: 42.31 min, p < .01), with no severe adverse events occurred in either group, such as endovenous heat-induced thrombosis or deep vein thrombosis. Postoperative pain (Group N, 0.53% vs Group T, 0.52%; p = .86), postoperative complications such as bruising (Group N, 6.78% vs Group T, 4%; N= .34) and paresthesia (Group N, 1.7% vs Group T, 6%; p = .27) showed no significant difference between the two groups on postoperative day 10. Conclusion: Tumescentless RFA with internal cooling and local hypothermia shows promising results with minimal complications. This novel approach represents a recent advancement in endovenous RFA that omits additional tumescent anesthesia.","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"202-210"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142335874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The profile beyond leg pain: In basis of central sensitization, kinesiophobia, and body awareness in patients with chronic venous disease. 腿痛之外的概况：慢性静脉疾病患者的中枢敏感性、运动恐惧症和身体意识的基础。

Phlebology Pub Date : 2025-04-01 Epub Date: 2024-09-24 DOI: 10.1177/02683555241286385

Zilan Bazancir-Apaydin, Elif Sakizli Erdal, Ilke Keser, Dilek Erer

{"title":"The profile beyond leg pain: In basis of central sensitization, kinesiophobia, and body awareness in patients with chronic venous disease.","authors":"Zilan Bazancir-Apaydin, Elif Sakizli Erdal, Ilke Keser, Dilek Erer","doi":"10.1177/02683555241286385","DOIUrl":"10.1177/02683555241286385","url":null,"abstract":"Objective: Leg pain has long been underestimated despite being one of the most important symptoms of chronic venous disease (CVD). Studies investigating leg pain and psychosocial profile in CVD are limited. The study aimed to investigate leg pain, central sensitization, kinesiophobia, and body awareness in patients with CVD. Methods: The ninety-eight patients (80 female, 18 male) diagnosed with CVD were included in the study. The severity of leg pain was evaluated with the Visual Analog Scale (VAS). The patients were assessed with the Central Sensitization Inventory (CSI-A and B) for central sensitization-related symptoms and -positivity, the Body Awareness Questionnaire (BAQ) for body awareness, and the Tampa Kinesiophobia Scale (TKS) for kinesiophobia. The cut-off score was admitted as 41 for TKS. Results: The leg pain (mean (SD) = 4.3 ± 2) and body awareness (mean (SD) = 82.4 ± 22) were moderate levels in patients with CVD. Nearly half of the patients (n = 46, 46.9%) had both central sensitization positivity and elevated kinesiophobia (n = 46, 47%). The CSI was correlated with the VAS (r = 0.32, p = .001), TKS (r = 0.40, p < .001), and BAQ (r = 0.20, p = .048). Significant correlations were determined between Body Mass Index and TKS (r = 0.48, p < .001) and BAQ (r = -0.31, p = .002). Also, the patients with a TKS score ≥41-points had higher CSI-A scores (p = .002) than those with a TKS score< 41. Conclusions: Leg pain, central sensitization, and kinesiophobia are commonly seen in patients with CVD, and central sensitization seems to have a negative effect on leg pain, kinesiophobia, and body awareness. The profile beyond pain should be evaluated in detail, and various rehabilitation strategies need to be developed to manage central sensitization, interoception, kinesiophobia, and weight control in patients with CVD.","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"182-190"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142309571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Deciphering the association between gut microbiome and varicose veins: A mendelian randomization study.

Phlebology Pub Date : 2025-03-28 DOI: 10.1177/02683555251329406

Yu Tian, Furong Hao, Jiantao Zhang, Yuxuan Qian, Jiahao Liu, Qianhui Bao, Haipeng Shi, Tianjie Li, Tao Yang

{"title":"Deciphering the association between gut microbiome and varicose veins: A mendelian randomization study.","authors":"Yu Tian, Furong Hao, Jiantao Zhang, Yuxuan Qian, Jiahao Liu, Qianhui Bao, Haipeng Shi, Tianjie Li, Tao Yang","doi":"10.1177/02683555251329406","DOIUrl":"https://doi.org/10.1177/02683555251329406","url":null,"abstract":"Background: Despite the well-documented influence of traditional risk factors on varicose veins, the potential causal role of the gut microbiome in this condition remains underexplored. This study aims to elucidate the association between specific gut microbial taxa and varicose veins using a Mendelian Randomization (MR) approach. Methods: Utilizing genome-wide association study datasets from the MiBioGen Consortium and the Finnish database, this study carefully selected instrumental variables based on their genetic association with the gut microbiome and stringent statistical criteria. Multiple MR techniques were applied to analyze the data, accompanied by comprehensive sensitivity analyses to ensure the reliability of the causal relationships between the gut microbiota and varicose veins. Results: The study identified three microbial taxa-genus Terrisporobacter, Coprococcus2, and Ruminococcus gnavus group-as protective factors against varicose veins. Conversely, the family Ruminococcaceae, genus Flavonifractor, and genus RuminococcaceaeUCG009 were associated with an increased risk of developing varicose veins. Bidirectional analyses indicated that the presence of varicose veins does not influence the abundance of these microbiota groups. Conclusion: The results of this study support a relationship between specific gut microbiota and varicose veins, revealing potential new targets for therapeutic intervention. These insights not only deepen our understanding of the pathophysiology of varicose veins but also provide a theoretical basis for future medical applications, highlighting the potential value of microbiome research in the prevention and treatment strategies for varicose veins.","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"2683555251329406"},"PeriodicalIF":0.0,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143736324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Retrospective evaluation of the results of ultrasound-accelerated catheter-directed tombolysis in acute-subacute pulmonary embolism patients.

Phlebology Pub Date : 2025-03-20 DOI: 10.1177/02683555251329766

Ali Fuat Karaçuha, İlyas Memmedyarov, Ahmet Kayan, Çağdaş Baran, Evren Özçinar, Nur Dikmen, Mustafa Şirlak, Sadık Eryilmaz

{"title":"Retrospective evaluation of the results of ultrasound-accelerated catheter-directed tombolysis in acute-subacute pulmonary embolism patients.","authors":"Ali Fuat Karaçuha, İlyas Memmedyarov, Ahmet Kayan, Çağdaş Baran, Evren Özçinar, Nur Dikmen, Mustafa Şirlak, Sadık Eryilmaz","doi":"10.1177/02683555251329766","DOIUrl":"https://doi.org/10.1177/02683555251329766","url":null,"abstract":"ObjectivesAcute pulmonary embolism (PE) is one of the most serious forms of venous thromboembolism (VTE) with high mortality and morbidity. PE may present with right ventricular dysfunction and hemodynamic disturbances. Early diagnosis and appropriate treatment approaches play a critical role in improving survival. In this study, we evaluated the efficacy and safety of catheter-mediated thrombolytic therapy in intermediate-high-risk PE patients.MethodsOur retrospective study was conducted at Ankara University between 2015 and 2020 and 66 intermediate-high-risk PE patients were analyzed. Clinical, biochemical and echocardiographic data of the patients were analyzed and their response to treatment was evaluated. The primary endpoint was 30-day mortality and secondary endpoints were hemodynamic improvement, length of hospitalization and complication rates.ResultsThe mean age of the patients was 65 years and all of them presented with a diagnosis of symptomatic PE. After treatment, significant improvement was observed in right ventricular function, RV/LV ratio, ProBNP and Troponin I levels decreased significantly. Pulmonary artery pressures decreased and hemodynamic parameters improved. The early mortality rate after the procedure was 3% and the rate of major bleeding was low.ConclusionsCatheter-mediated thrombolytic therapy provides hemodynamic improvement in intermediate-high-risk PE patients, while offering a low bleeding risk. Our results suggest that this therapy may be a safe and effective alternative. However, long-term results should be evaluated in large-scale, randomized studies.","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"2683555251329766"},"PeriodicalIF":0.0,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143672159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of static foot disorder and ankle range of motion in chronic venous insufficiency patients.

Phlebology Pub Date : 2025-03-17 DOI: 10.1177/02683555251326046

Sree Vani Paladugu, Ajay Savlania, Gokulkrishnan Hari, Tanuj Singla, Ujjwal Gorsi, Lileswar Kaman

{"title":"Impact of static foot disorder and ankle range of motion in chronic venous insufficiency patients.","authors":"Sree Vani Paladugu, Ajay Savlania, Gokulkrishnan Hari, Tanuj Singla, Ujjwal Gorsi, Lileswar Kaman","doi":"10.1177/02683555251326046","DOIUrl":"https://doi.org/10.1177/02683555251326046","url":null,"abstract":"ObjectiveChronic venous insufficiency (CVI) is a progressive disease, leading to calf muscle pump dysfunction and reduced range of ankle motion (ROAM). A full ROAM increases venous return decreasing venous hypertension. The dysfunction of foot pump in static foot disorder (SFD) further contributes to chronic venous insufficiency. In present study we studied the effect of ROAM and SFD on CVI.MethodsA prospective observational study was conducted from July 2022 to June 2023, with Institute Ethical clearance (INT/2022/MS-533). A total of 402 legs were included, of which 368 legs of the study group had CVI and 34 legs were in control C0 group. Patients were divided into control C0, mild C1-C3 and advanced C4-C6 disease group based on the severity of CVI. SFD and ROAM were evaluated from X-rays by Djian-Annonier angle and goniometry respectively. The primary objective was to study, impairment of ROAM in patients from C1-C6 and its comparison with control C0 group and impact of static foot disorders on ROAM.ResultsROAM was highest in controls and decreased towards the lowest value in progression to advanced stages of CEAP classification (87° in C0, 71° in mild CVI and 45° in advanced CVI, p < .001). Controls had just nine % legs afflicted with SFD whereas 62.3% and 68.6% with mild and advanced disease had SFD, p < .001. ROAM was highest in those without SFD (68.9°) and least in hollow feet (58.3°), p < .001. ROAM was lower in the symptomatic C2 disease (80°) than asymptomatic type (69°) (p < .001).ConclusionThis study showed that poor ROAM is associated with higher rate of advance CVI. In addition patients with SFD had advance CVI and poor ROAM. So, it is important to consider treatment of SFD and physical rehabilitation to improve ROAM and break vicious cycle of progression to severe CVI.","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"2683555251326046"},"PeriodicalIF":0.0,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143652478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of clinical and ultrasonographic prognostic factors for detection of iliac venous obstructions in patients with advanced chronic venous insufficiency.

Phlebology Pub Date : 2025-03-17 DOI: 10.1177/02683555251326040

Viviane Chaib Gomes Stegun, Patrick Bastos Metzger, Ana Amélia Carvalho Melo Cavalcante, Thaís Lye Okamoto Yamakami, Fabio Henrique Rossi

{"title":"Evaluation of clinical and ultrasonographic prognostic factors for detection of iliac venous obstructions in patients with advanced chronic venous insufficiency.","authors":"Viviane Chaib Gomes Stegun, Patrick Bastos Metzger, Ana Amélia Carvalho Melo Cavalcante, Thaís Lye Okamoto Yamakami, Fabio Henrique Rossi","doi":"10.1177/02683555251326040","DOIUrl":"https://doi.org/10.1177/02683555251326040","url":null,"abstract":"ObjectiveThis study evaluated clinical and ultrasonographic prognostic factors correlated with iliac venous obstructions (IVO) in patients with advanced chronic venous insufficiency (CVI).MethodsSixty-six patients with CVI were classified into Group I (CEAP C1-C2) or Group II (CEAP C3-C6) and categorized by IVO severity (<50%, 50%-79%, ≥80%). Factors analyzed included age, gender, ethnicity, body mass index (BMI), diabetes, deep vein thrombosis (DVT) history, limb laterality, and reflux in superficial, deep, and perforator venous systems. Multivariate logistic regression identified associations, with odds ratios (OR) calculated at a 95% confidence interval.ResultsPatients in both groups were predominantly female, white, and of similar age. Group I patients had higher BMI and lower abdominal circumference than Group II. Arterial hypertension was common in both groups, but deep vein thrombosis history was absent in Group I and present in 27.45% of Group II. Venous reflux was more frequent in Group II (74.5%) compared to Group I (36.7%). Regarding severity of IVO in Group II, 50% of limbs had <50% obstruction, 26.5% of limbs had 50%-79% obstruction, and 23.5% of limbs had ≥80% obstruction. Left limb was more frequently affected (70.58%) in significant obstructions found in Group II. Positive correlations were observed between IVO, non-recanalized DVT, and venous obstruction severity. Reflux in the deep venous system was a significant predictor for severe IVO in advanced chronic venous insufficiency patients (OR = 3.7, p = .02).ConclusionsDeep venous reflux was shown to be a prognostic factor for detecting critical IVO in patients with advanced CVI. History of DVT, presence of reflux in the venous system of the lower limbs and non-recanalized DVT in advanced chronic venous insufficiency patients indicate the need for screening for IVO additional cross-sectional imaging.","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"2683555251326040"},"PeriodicalIF":0.0,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143653107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Application of preoperative ultrasound combined with indocyanine green lymphography in lymphaticovenular anastomosis of the lower limb-A retrospective study research.

Phlebology Pub Date : 2025-03-14 DOI: 10.1177/02683555251326039

Bin Liu, Xuchuan Zhou, Yu Zheng, Xuefeng Su, Xinyi Li, Chengcheng Gao, Gejia Ma

引用次数: 0