Phlebology最新文献

{"title":"Relationship of the tissue stiffness measured using shear wave elastography with the pain threshold and quality of life of patients with lipedema: A cross-sectional study.","authors":"Gulcan Ozturk, Ahmet Nedim Kahraman, Pinar Akpinar, Umut Utangac, Duygu Silte Karamanlioglu, Feyza Akan Begoglu, Feyza Unlu Ozkan, Ilknur Aktas, Ahmet Vural","doi":"10.1177/02683555251357094","DOIUrl":"10.1177/02683555251357094","url":null,"abstract":"<p><p>ObjectiveTo assess the relationship between disease severity in lipedema and tissue stiffness measured using shear wave elastography (SWE) concerning pain threshold and quality of life as well as determine differences in subcutaneous tissue stiffness between patients with lipedema and healthy subjects.Methods71 participants were subjected to measurements using subcutaneous tissue elastic modulus with SWE imaging of lower limbs at three anatomical levels. The participants were divided into two groups: those diagnosed with lipedema (Group (1) (<i>n</i> = 35) and healthy subjects (Group (2) (<i>n</i> = 36). Patients with lipedema were categorized into three stages based on disease severity. Pain levels were assessed using the visual analog scale (VAS), pain pressure threshold through algometric measurement within lipedema stages, and quality of life using EQ-5D quality of life scale in all groups.ResultsNo statistically significant differences in age, BMI, right and left three-zone elastic modulus averages were observed between the groups within BMI levels of 25-29.9 and ≥30 kg/m² (<i>p</i> > .05). Same BMI group, according to lipedema stage, the mean elastic modulus of the right pretibial region in stage 2 cases was significantly higher than in stage 1 cases within BMI levels of 25-29.9 kg/m² (<i>p</i> < .05). The all-region algometric measurements in Group 1 were significantly lower than those in Group 2, within BMI levels of 25-29.9 kg/m² and ≥30 kg/m². The average spontaneous VAS scores in Group 1 were significantly higher than those in Group 2 within the same BMI (<i>p</i> < .05). The VAS palpation scores in Group 1 exceeded those in Group 2 for BMI ≥30 kg/m² (<i>p</i> < .05). No significant difference in VAS palpation scores was observed for BMI 25-29.9 kg/m² (<i>p</i> > .05). The EQ-5D VAS scores of the control group were significantly lower than those of stage 1, 2, and 3 cases (<i>p</i> < .05).ConclusionsIn lipedema, pain characteristics may be more distinctive than the elastic properties of adipose tissue. Increased algometric measurements may reflect a specific objective sensation.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"627-637"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144651716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of preoperative ultrasound combined with indocyanine green lymphography in lymphaticovenular anastomosis of the lower limb-A retrospective study research.","authors":"Bin Liu, Xuchuan Zhou, Yu Zheng, Xuefeng Su, Xinyi Li, Chengcheng Gao, Gejia Ma","doi":"10.1177/02683555251326039","DOIUrl":"10.1177/02683555251326039","url":null,"abstract":"<p><p>BackgroundWe evaluated the application of preoperative ultrasound (US) combined with indocyanine green (ICG) lymphography in lymphaticovenular anastomosis (LVA) of the lower limb.Methods66 patients with lower limb lymphedema were selected as study subjects and divided into research (<i>n</i> = 35) and control groups (<i>n</i> = 31). The patients were treated with LVA using ICG lymphography combined with US and simple ICG lymphography as the positioning method. The number of lymphatic vessels anastomosed, diameter, depth, and searching time were compared.ResultsThe number of anastomotic lymphatic vessels in the research group was more than in the control group (<i>p</i> < .05). Compared with the lymphatic vessels under ICG lymphography, the lymphatic vessels under US locating had less search time, larger diameter, and deeper depth (<i>p</i> < .05).ConclusionUS combined with ICG lymphography in preoperative can increase the number of lymphatic vessels and shorten the time to find lymphatic vessels.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"590-599"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143631165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lipedema awareness in fibromyalgia.","authors":"Elzem Bolkan Günaydın, Zeliha Ünlü, Saime Ay, Tolga Oğuz Karapınar","doi":"10.1177/02683555251321042","DOIUrl":"10.1177/02683555251321042","url":null,"abstract":"<p><p>ObjectivesTo evaluate the presence of lipedema and lipedema-related factors in fibromyalgia patients.MethodsThe study included 100 female patients over the age of 18 who met the fibromyalgia diagnostic criteria. The patients were evaluated for the presence/stages of lipedema. The body mass index (BMI), waist-hip ratio, waist-height ratio, and presence of hematoma tendency/telangiectasias were recorded. Patients were asked to mark the severity of their pain (widespread/on lipedema) on a 10 cm visual analog scale (VAS). The ACR 2016 Fibromyalgia Diagnostic Criteria, The Beck Depression Inventory (BDI), and The Revised Fibromyalgia Impact Questionnaire were applied.ResultsLipedema was observed in 50% of the patients (58% Stage 1 lipedema). In the lipedema group, age, duration of fibromyalgia diagnosis, hematoma tendency/presence of telangiectasias (for all; <i>p</i> < .001), menopausal status (<i>p</i> = .004), BDI score (<i>p</i> = .04), BMI (<i>p</i> = .02), history of medication for fibromyalgia (<i>p</i> = .01) were higher, and age at menarche (<i>p</i> = .01) was lower. Lipedema stage was moderately positively correlated with BMI, number of pregnancies (for both; r:0.53 <i>p</i> < .001) and waist-height ratio (r:0.43 <i>p</i>:0.002), while VAS-lipedema pain intensity was strongly positively correlated with VAS-widespread pain intensity (r:0.62 <i>p</i> < .001), and moderately positively correlated with symptom severity score (r:0.55 <i>p</i> < .001), BMI (r:0.54 <i>p</i> < .001), and fibromyalgia severity score (r:0.51 <i>p</i> < .001). Long fibromyalgia diagnosis time (<i>p</i>: 0.005), and low age at menarche (<i>p</i>: 0.05) were significant risk factors for the presence of lipedema.ConclusionsLipedema is common in fibromyalgia patients. Long fibromyalgia diagnosis time and low age at menarche are significant risk factors for the presence of lipedema.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"559-569"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143416471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of static foot disorder and ankle range of motion in chronic venous insufficiency patients.","authors":"Sree Vani Paladugu, Ajay Savlania, Gokulkrishnan Hari, Tanuj Singla, Ujjwal Gorsi, Lileswar Kaman","doi":"10.1177/02683555251326046","DOIUrl":"10.1177/02683555251326046","url":null,"abstract":"<p><p>ObjectiveChronic venous insufficiency (CVI) is a progressive disease, leading to calf muscle pump dysfunction and reduced range of ankle motion (ROAM). A full ROAM increases venous return decreasing venous hypertension. The dysfunction of foot pump in static foot disorder (SFD) further contributes to chronic venous insufficiency. In present study we studied the effect of ROAM and SFD on CVI.MethodsA prospective observational study was conducted from July 2022 to June 2023, with Institute Ethical clearance (INT/2022/MS-533). A total of 402 legs were included, of which 368 legs of the study group had CVI and 34 legs were in control C0 group. Patients were divided into control C0, mild C1-C3 and advanced C4-C6 disease group based on the severity of CVI. SFD and ROAM were evaluated from X-rays by Djian-Annonier angle and goniometry respectively. The primary objective was to study, impairment of ROAM in patients from C1-C6 and its comparison with control C0 group and impact of static foot disorders on ROAM.ResultsROAM was highest in controls and decreased towards the lowest value in progression to advanced stages of CEAP classification (87° in C0, 71° in mild CVI and 45° in advanced CVI, <i>p</i> < .001). Controls had just nine % legs afflicted with SFD whereas <i>62.3% and 68.6% with mild and advanced disease had SFD, p < .001</i>. ROAM was highest in those without SFD (68.9°) and least in hollow feet (58.3°), <i>p < .001</i>. ROAM was lower in the symptomatic C2 disease (80°) than asymptomatic type (69°) (<i>p</i> < .001).ConclusionThis study showed that poor ROAM is associated with higher rate of advance CVI. In addition patients with SFD had advance CVI and poor ROAM. So, it is important to consider treatment of SFD and physical rehabilitation to improve ROAM and break vicious cycle of progression to severe CVI.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"609-616"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143652478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The efficacy of aspirin compared to low molecular weight heparin as thromboprophylaxis after orthopedic surgery: A systematic review and meta-analysis.","authors":"Feng Chen, Jing Guo","doi":"10.1177/02683555251325415","DOIUrl":"10.1177/02683555251325415","url":null,"abstract":"<p><p><b>Background:</b> Aspirin has increasingly gained attention as a thromboprophylaxis agent for patients undergoing orthopedic surgery; however, the results of recent clinical trials remain controversial. Therefore, in this meta-analysis, we compared the safety and efficacy of aspirin with those of low molecular weight heparin (LMWH) for patients undergoing major orthopedic surgeries leading to significant immobility and necessitating anticoagulants to prevent thromboembolic events. <b>Methods:</b> PubMed, Web of Science, Scopus, and the Cochrane Library were systematically searched from the inception to April 20, 2024, to identify clinical trials and randomized controlled trials comparing the effect of aspirin and LMWH on deep vein thrombosis (DVT), pulmonary thromboembolism (PTE), venous thromboembolism (VTE), major bleeding, short-term postoperative mortality, and adherence to treatment. VTE included DVT and PE in this study. A random-effects model (<i>DerSimonian-Laird</i>) was employed to pool data. <b>Results:</b> In total, 8 randomized controlled trials with 23,540 participants were included in this study. Compared to LMWH, the use of aspirin was associated with a significantly increased risk of DVT (RR 1.56, 95% CI (1.30-1.86), I² = 0.00%), whereas no significant changes were observed in drug adherence (RR 1.04, 95% CI (0.94-1.14), I² = 94.02%) and risk of PTE (RR 1.18, 95% CI (0.64-2.15), I² = 58.64%), VTE (RR 1.51, 95% CI (0.89-2.57), I² = 24.69%), major bleeding (RR 0.96, 95% CI (0.88-1.04), I² = 0.00%), and mortality (RR 1.07, 95% CI (0.89-1.29), I² = 0.00%) after orthopedic surgery. <b>Conclusion:</b> Aspirin is generally as safe as LMWH for preventing thromboembolic events among patients undergoing orthopedic surgery; however, aspirin can increase the risk of DVT.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"551-558"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143627319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antithrombotic therapies for patients with acute iliofemoral deep vein thrombosis following endovenous recanalization: A single-center study and literature review.","authors":"Nedaa Skeik, Rina Li, Ellen Cravero, Bjorn Engstrom, Jesse Manunga","doi":"10.1177/02683555251321903","DOIUrl":"10.1177/02683555251321903","url":null,"abstract":"<p><p>ObjectivesThere is no consensus regarding the optimal antithrombotic therapy following endovenous recanalization. We aim to assess the effectiveness of anticoagulant, antiplatelet, or combination therapy to provide evidence-based recommendations for antithrombotic therapy following interventional procedures.MethodsAn Institutional Review Board approved, retrospective study of patients presented to our facility with iliofemoral venous thrombosis requiring thrombolysis and/or thrombectomy with or without venous angioplasty/stenting between January 1, 2010 and April 1, 2023. Incidence of vein or stent patency, thrombosis, and bleeding were considered primary endpoints and were compared between patients on anticoagulant, antiplatelet, or combination therapies at each post-interventional surveillance, up to five visits.ResultsThe cohort yielded 128 patients, including 116 adults and 12 minors. We identified a notable trend in the post-recanalization medical routines of patients: those initially prescribed combination therapy post-procedure eventually transitioned to either exclusive anticoagulant or antiplatelet therapy. The initial combination antithrombotic therapy was associated with trends towards higher vein patency (59% vs 47% with anticoagulant vs 25% antiplatelet, <i>p</i> = .3), less recurrent vein and stent thrombosis (46% vs 54% with anticoagulants vs 100% antiplatelet, <i>p</i> = .10), and overall low major bleeding complications (3.2% vs 6.8% anticoagulant, <i>p</i> = .5) at first follow-up compared to those on anticoagulant or antiplatelet regimens alone.ConclusionAlthough the optimal post-interventional antithrombotic therapy remains uncertain, combination therapy was associated with trends towards higher vein patency and lower recurrent thrombosis, with low overall major bleeding complications at the first follow-up visit following interventions. Future studies encompassing larger and more diverse populations are essential to corroborate the findings presented in this report and offer valuable insights for optimizing the management of patients with this condition.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"570-580"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143451363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A hemodynamic screening tool for symptomatic internal jugular vein stenosis in J3 segment.","authors":"Min Li, Xiaogang Gao, Yaqiong Jia, Yang Wang, Xunming Ji, Ran Meng","doi":"10.1177/02683555251326031","DOIUrl":"10.1177/02683555251326031","url":null,"abstract":"<p><p>ObjectivesThe aim of this study was to formulate an ultrasonic diagnostic criterion for stenosis in the J3 segment of internal jugular vein (IJV) and probe into the effects of stenosis in the J3 segment on intracranial pressure (ICP) and the cerebral drainage pattern.MethodsParticipants who exhibited narrowing in the J3 segment of IJV on neuroimaging and reported symptoms correlated with IJV stenosis (IJVS) were enlisted from Xuanwu Hospital. Clinical data were retrospectively amassed.ResultsA total of 163 subjects including 57 IJVS subjects and 106 control subjects were recruited. We unearthed an inverse relationship between the pressure gradient and the flow velocity. Flow velocity at or below 27.5 cm/s coincided with pressure gradient values of 4 mmHg or greater. There is no significant correlation between IJVS and ICP. Additionally, a linear correlation was identified between the bilateral flow volume in the J3 segment and ICP. Values exceeding 425 mL/min were indicative of intracranial hypertension. There was an increase in diameter, flow volume and flow velocity in the bilateral vertebral veins in participants with IJVS.ConclusionsThe J3 segment of IJV displays right dominance. Stenosis can be deduced when the flow velocity in the J3 segment is at or below 27.5 cm/s. Stenosis in the J3 segment yielded a diminished outflow in the IJV and an augmented outflow in the vertebral veins. When bilateral flow volume in the J3 segment exceeds 425 mL/min, it denotes intracranial hypertension.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"581-589"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143607596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Selected phlebological abstracts.","authors":"Lowell S Kabnick, Kathleen Ozsvath, Jorge H Ulloa","doi":"10.1177/02683555251367197","DOIUrl":"10.1177/02683555251367197","url":null,"abstract":"","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"641-643"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144765969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk acceptance for deep venous interventions of the lower limb.","authors":"George Hudson, Desmond Chan, Robert Hinchliffe, Baris Ozdemir","doi":"10.1177/02683555251326711","DOIUrl":"10.1177/02683555251326711","url":null,"abstract":"<p><p><b>Objectives:</b> To discover the maximum risk acceptable to patients and clinicians for complications typical to endovascular interventions in the setting of proximal deep vein thrombosis (DVT) and post-thrombotic syndrome (PTS).<b>Design:</b> This was an observational study comparing patient/clinician risk acceptances in interviews using validated Standard Gamble methodology.<b>Methods:</b> 30 patients with previous DVT and 30 vascular clinicians were given a scenario describing a hypothetical case of a patient being managed with acute iliofemoral DVT and another with PTS. Subjects were asked to provide the maximum risk they would accept for individual complications to cure the condition. To interpret variability, the Venous Clinical Severity Score, SF-36 domains and VEINES-QoL for each patient were plotted against their risk acceptance for major bleeding in the DVT scenario.<b>Results:</b> For the DVT scenario, patients accepted high median risks compared to clinicians for major bleeding (40% vs 5%, <i>p</i> < .001), bleeding at other sites (50% vs 5%, <i>p</i> < .001), damage to blood vessels (60% vs 5%, <i>p</i> < .001), further procedures (80% vs 20%, <i>p</i> < .001), and treatment failure (75-80% vs 10-20%, <i>p</i> < .001). However, the gap was lower for intracranial bleeding (5% vs 1%, <i>p</i> = .004), pulmonary embolism (5 vs 5%, <i>p</i> = .39) or death (1% vs 0.75%, <i>p</i> = .77). For the PTS scenario, there were similar results again with a lower difference for pulmonary embolism (10% vs 5%, <i>p</i> = .02) and death (0.5% vs 1%, <i>p</i> = .72). Importantly, patient risk acceptance for major bleeding was negatively correlated to the emotional wellbeing (Rho = -0.43, <i>p</i> = .018) and social functioning (Rho = -0.38, <i>p</i> = .042) SF-36 domains.<b>Conclusion:</b> Overall, patients accepted a greater chance of most adverse events compared with clinicians. Patients prepared to accept greater risk were those with poorer emotional wellbeing and social functioning. It is important to take these issues into account when making shared decisions with patients about the management of their DVT/PTS.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"617-626"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of clinical and ultrasonographic prognostic factors for detection of iliac venous obstructions in patients with advanced chronic venous insufficiency.","authors":"Viviane Chaib Gomes Stegun, Patrick Bastos Metzger, Ana Amélia Carvalho Melo Cavalcante, Thaís Lye Okamoto Yamakami, Fabio Henrique Rossi","doi":"10.1177/02683555251326040","DOIUrl":"10.1177/02683555251326040","url":null,"abstract":"<p><p>ObjectiveThis study evaluated clinical and ultrasonographic prognostic factors correlated with iliac venous obstructions (IVO) in patients with advanced chronic venous insufficiency (CVI).MethodsSixty-six patients with CVI were classified into Group I (CEAP C1-C2) or Group II (CEAP C3-C6) and categorized by IVO severity (<50%, 50%-79%, ≥80%). Factors analyzed included age, gender, ethnicity, body mass index (BMI), diabetes, deep vein thrombosis (DVT) history, limb laterality, and reflux in superficial, deep, and perforator venous systems. Multivariate logistic regression identified associations, with odds ratios (OR) calculated at a 95% confidence interval.ResultsPatients in both groups were predominantly female, white, and of similar age. Group I patients had higher BMI and lower abdominal circumference than Group II. Arterial hypertension was common in both groups, but deep vein thrombosis history was absent in Group I and present in 27.45% of Group II. Venous reflux was more frequent in Group II (74.5%) compared to Group I (36.7%). Regarding severity of IVO in Group II, 50% of limbs had <50% obstruction, 26.5% of limbs had 50%-79% obstruction, and 23.5% of limbs had ≥80% obstruction. Left limb was more frequently affected (70.58%) in significant obstructions found in Group II. Positive correlations were observed between IVO, non-recanalized DVT, and venous obstruction severity. Reflux in the deep venous system was a significant predictor for severe IVO in advanced chronic venous insufficiency patients (OR = 3.7, <i>p</i> = .02).ConclusionsDeep venous reflux was shown to be a prognostic factor for detecting critical IVO in patients with advanced CVI. History of DVT, presence of reflux in the venous system of the lower limbs and non-recanalized DVT in advanced chronic venous insufficiency patients indicate the need for screening for IVO additional cross-sectional imaging.</p>","PeriodicalId":94350,"journal":{"name":"Phlebology","volume":" ","pages":"600-608"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143653107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}