European heart journal. Imaging methods and practice最新文献

{"title":"Prediction of tricuspid regurgitation regression after mitral valve transcatheter edge-to-edge repair using three-dimensional transoesophageal echocardiography.","authors":"Makoto Takeuchi, Hiroto Utsunomiya, Kiyotaka Tohgi, Ayano Hamada, Yohei Hyodo, Akane Tsuchiya, Atsuo Mogami, Hajime Takemoto, Kanako Izumi, Kosuke Takahari, Yusuke Ueda, Kiho Itakura, Hiroki Ikenaga, Yukiko Nakano","doi":"10.1093/ehjimp/qyaf016","DOIUrl":"10.1093/ehjimp/qyaf016","url":null,"abstract":"<p><strong>Aims: </strong>We aimed to identify three-dimensional echocardiographic predictors of tricuspid regurgitation (TR) regression in patients with functional TR of moderate or greater severity undergoing mitral valve transcatheter edge-to-edge repair to optimize patient selection and improve clinical outcomes.</p><p><strong>Methods and results: </strong>This retrospective study analysed 61 patients (mean age 81.3 ± 7.6 years; 55.7% males) who underwent mitral valve transcatheter edge-to-edge repair. Two-dimensional transthoracic echocardiography was performed pre- and 1-month post-procedurally, while three-dimensional transoesophageal echocardiography was performed pre-procedurally. We collected data on clinical variables, medications, and detailed echocardiographic measurements to evaluate procedural outcomes. Tricuspid regurgitation severity was semiquantitatively assessed and categorized. At the 1-month follow-up, TR severity had regressed in 43% of patients. A lower prevalence of atrial fibrillation, smaller left atrial volume index, and smaller right atrial area were significantly associated with TR regression. Multivariate analysis revealed the tricuspid valve annulus perimeter, area, and area change as significant predictors of post-procedure TR regression; tricuspid valve annulus perimeter was the strongest predictor among the three indicators [area under the receiver operating characteristic curve, 0.84 (95% confidence interval: 0.75-0.94), <i>P</i> < 0.001]. Receiver operating characteristic curve analysis indicated that tricuspid valve annulus perimeter cut-off of ≤13.75 cm was the best predictor of post-procedure TR regression. Additionally, tricuspid valve annulus area ≤13.55 cm² and annulus area change ≥17.5% were predictors of post-procedure TR regression.</p><p><strong>Conclusion: </strong>In patients with relatively severe mitral regurgitation with a non-dilated tricuspid annulus and significant change in tricuspid valve annulus area, mitral valve transcatheter edge-to-edge repair may lead to TR regression.</p>","PeriodicalId":94317,"journal":{"name":"European heart journal. Imaging methods and practice","volume":"3 1","pages":"qyaf016"},"PeriodicalIF":0.0,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11811635/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143401128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of technical, patient-related and measurement variables on serial Hounsfield unit-based quantitative coronary plaque analysis in computed tomography: time for a new chapter.","authors":"Francesca Calicchio, Elizabeth Epstein, Melinda Boussoussou, Borbála Vattay, Alexander van Rosendael, Shawn Newlander, Márton Kolossváry, Bálint Szilveszter, Pál Maurovich-Horvat, Hugo Marques, Elliot McVeigh, George Wesbey","doi":"10.1093/ehjimp/qyaf014","DOIUrl":"10.1093/ehjimp/qyaf014","url":null,"abstract":"<p><p>This review article explores the challenges and controversies involved in accurately identifying and reliably quantifying coronary plaque over time through coronary computed tomography angiography (CCTA), particularly focusing on lipid-rich, low-attenuation plaques. It highlights significant variability in lipid-rich plaque measurements across studies, questioning their reliability for tracking biological plaque transformation in clinical practice. To address this issue, the review article proposes suggestions for serial CCTA plaque measurements, aiming for realistic goals for reproducible and meaningful serial plaque CCTA imaging. It also emphasizes the necessity of standardized, validated methods for quantitative plaque analysis and underscores the potential of phantom-based calibration to improve the reliability and consistency of serial plaque measurements in clinical practice.</p>","PeriodicalId":94317,"journal":{"name":"European heart journal. Imaging methods and practice","volume":"3 1","pages":"qyaf014"},"PeriodicalIF":0.0,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11891479/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143598695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New ways to use imaging data in cardiovascular research: survey of opinions on federated learning and synthetic data.","authors":"Michelle C Williams, Jacqueline A L MacArthur, Ross Forsyth, Steffen E Petersen","doi":"10.1093/ehjimp/qyaf012","DOIUrl":"10.1093/ehjimp/qyaf012","url":null,"abstract":"<p><strong>Aims: </strong>Federated learning and the creation of synthetic data are emerging tools, which may enhance the use of imaging data in cardiovascular research. This study sought to understand the perspectives of cardiovascular imaging researchers on the potential benefits and challenges associated with these technologies.</p><p><strong>Methods and results: </strong>The British Heart Foundation Data Science Centre conducted a series of online surveys and a virtual workshop to gather insights from stakeholders involved in cardiovascular imaging research about federated learning and synthetic data generation. The federated learning survey included 67 respondents: 18% (<i>n</i> = 12) were currently using federated learning, 4% (<i>n</i> = 3) had previously used it, 31% (<i>n</i> = 21) were planning to use it, and 46% (<i>n</i> = 31) were neither using nor planning to use it. Highlighted benefits included data privacy and enhanced collaboration, while challenges included data heterogeneity and technical complexity. The synthetic data survey had 22 respondents: 50% (<i>n</i> = 11) were currently using synthetic imaging data, 36% (<i>n</i> = 8) expressed interest in using it, and 14% (<i>n</i> = 3) thought it should not be used. Amongst the respondents, 50% had created synthetic imaging data and 45% had used it in cardiovascular research. Advantages cited included privacy preservation, increased dataset size and diversity, improved data access, and reduced administrative burden. Concerns included potential biases, trust issues, privacy concerns, and the fact that the images were not real and may have limited diversity or quality.</p><p><strong>Conclusion: </strong>Federated learning and synthetic data offer opportunities for advancing cardiovascular imaging research by addressing data privacy concerns and expanding data availability. However, challenges must be addressed to realize their full potential.</p>","PeriodicalId":94317,"journal":{"name":"European heart journal. Imaging methods and practice","volume":"3 1","pages":"qyaf012"},"PeriodicalIF":0.0,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11891443/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143598714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The silent threat: unruptured sinus of Valsalva aneurysm presenting as complete heart block.","authors":"Akshay Prashanth, Bharath Raj Kidambi, Ramesh Sankaran, Nagendra Boopathy Senguttuvan, Periyasamy Thangavelu, Ranjith Karthikeyan, Vijay Kumar Muthayala","doi":"10.1093/ehjimp/qyaf005","DOIUrl":"https://doi.org/10.1093/ehjimp/qyaf005","url":null,"abstract":"","PeriodicalId":94317,"journal":{"name":"European heart journal. Imaging methods and practice","volume":"3 1","pages":"qyaf005"},"PeriodicalIF":0.0,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11833493/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143451362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Barriers to cardiovascular magnetic resonance imaging scan performance and reporting by cardiologists: a systematic literature review.","authors":"Tesfamariam Betemariam, Abeba Aleka, Ekram Ahmed, Tinsae Worku, Yonas Mebrahtu, Emmanuel Androulakis, Steffen E Petersen, Rocco Friebel","doi":"10.1093/ehjimp/qyaf010","DOIUrl":"10.1093/ehjimp/qyaf010","url":null,"abstract":"<p><strong>Aims: </strong>Cardiovascular magnetic resonance (CMR) imaging plays a pivotal role in diagnosing and managing cardiovascular diseases. Its use has shown sustained growth over the past years. However, there is considerable variability in the use and reporting of CMR scans worldwide. This review provides synthesis of evidence on the barriers and challenges to performing CMR scans by cardiologists and gain insights into the variations in CMR scan practices across different countries.</p><p><strong>Methods and results: </strong>We systematically reviewed the literature from 1 January 2003 up to 13 November 2023. We searched four databases (Ovid Medline, Embase, Web of Science, and Scopus) and hand-searched the references in the included articles, complemented by expert feedback. Articles were double screened against pre-defined inclusion and exclusion criteria. We conducted risk of bias using the JBI critical appraisal tool, and we analysed information using a narrative synthesis of results. We identified 14 857 articles, with 13 articles meeting the inclusion criteria. The key barriers were the limited availability of CMR scanners, resulting in extended waiting times, the high service cost, and limited training opportunities and the lack of a structured curriculum. The main practice variations identified were geographical disparities in CMR use. Worldwide, the majority of CMR training programmes are situated in radiology departments.</p><p><strong>Conclusion: </strong>Barriers to CMR use by cardiologists range from access to scanners and prohibitive costs to disparities in familiarity with CMR technology. Geographic variations and heterogeneity in training programmes underscore the influence of systemic factors such as healthcare infrastructure, reimbursement policies, and unstandardized training curricula.</p>","PeriodicalId":94317,"journal":{"name":"European heart journal. Imaging methods and practice","volume":"3 1","pages":"qyaf010"},"PeriodicalIF":0.0,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11879352/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143559837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Non-invasive pressure-volume loops provide incremental value to age, sex, and infarct size for predicting adverse cardiac remodelling after ST-elevation myocardial infarction.","authors":"Theodor Lav, Thomas Engstrøm, Kasper Kyhl, David Nordlund, Jacob Lønborg, Henrik Engblom, David Erlinge, Håkan Arheden","doi":"10.1093/ehjimp/qyaf008","DOIUrl":"10.1093/ehjimp/qyaf008","url":null,"abstract":"<p><strong>Aims: </strong>This study aimed to assess the predictive value of non-invasive pressure-volume (PV) loop variables by cardiovascular magnetic resonance (CMR) for determining development of adverse remodelling 3 months after primary percutaneous coronary intervention (PCI) for ST-elevation myocardial infarction (STEMI).</p><p><strong>Methods and results: </strong>In total, 181 STEMI patients examined with CMR during the index admission (baseline) after primary PCI and at 3-month follow-up in The Third DANish Study of Optimal Acute Treatment of Patients with STEMI (DANAMI-3) study were retrospectively analysed. A time-varying elastance model for generating PV loops from CMR volumetry and brachial blood pressure was used to calculate contractility, arterial elastance, stroke work, potential energy, efficiency, external power, ventriculoarterial coupling, and energy per ejected volume. Adverse remodelling was seen in 28 patients (15%), defined as a concomitant increase in end-diastolic and end-systolic volume of ≥12% from baseline to follow-up. PV loop variables measured at baseline showed predictive value for adverse remodelling, independent of age, sex, and infarct size (IS) by a logistic regression analysis: contractility [odds ratio (OR) 4.6, 95% confidence interval (CI) 1.8-12.4] and efficiency (OR 1.05, 95% CI 1.00-1.11). Furthermore, females showed a higher increase in contractility between the timepoints (ΔContractility = 0.4 ± 0.4 mmHg/mL vs. 0.1 ± 0.4 mmHg/mL, <i>P</i> < 0.0001). A higher energy expenditure was seen at baseline in left arterial descending artery infarctions compared to left circumflex artery and right coronary artery infarctions.</p><p><strong>Conclusion: </strong>Non-invasive PV loop variables by CMR have incremental predictive value to age, sex, and IS for determining development of adverse cardiac remodelling in STEMI patients treated with primary PCI. Furthermore, the PV loop variables show significant differences in post-infarct cardiovascular adaptation between sexes and culprit vessels.</p>","PeriodicalId":94317,"journal":{"name":"European heart journal. Imaging methods and practice","volume":"3 1","pages":"qyaf008"},"PeriodicalIF":0.0,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11842901/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143485124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coronary complications in Kawasaki disease: giant aneurysms and thrombosis leading to myocardial infarction.","authors":"Jacobo Sebastián Vera-Chávez, Carlos Antonio Villegas-Chávez, Gabriela Meléndez-Ramírez, María Del Carmen López-Rodríguez, Karina Del Valle Zamora","doi":"10.1093/ehjimp/qyae116","DOIUrl":"https://doi.org/10.1093/ehjimp/qyae116","url":null,"abstract":"","PeriodicalId":94317,"journal":{"name":"European heart journal. Imaging methods and practice","volume":"3 1","pages":"qyae116"},"PeriodicalIF":0.0,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11740313/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143019460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical significance of the estimation of pulmonary-right ventricular uncoupling in patients with transthyretin amyloid cardiomyopathy.","authors":"Hiroki Usuku, Eiichiro Yamamoto, Kasumi Miyazaki, Ryudai Higashi, Atsushi Nozuhara, Fumi Oike, Naoto Kuyama, Noriaki Tabata, Masanobu Ishii, Shinsuke Hanatani, Tadashi Hoshiyama, Hisanori Kanazawa, Daisuke Sueta, Yuichiro Arima, Seitaro Oda, Hiroaki Kawano, Yasushi Matsuzawa, Yasuhiro Izumiya, Mitsuharu Ueda, Yasuhito Tanaka, Kenichi Tsujita","doi":"10.1093/ehjimp/qyae113","DOIUrl":"https://doi.org/10.1093/ehjimp/qyae113","url":null,"abstract":"<p><strong>Aims: </strong>There are few data on the prognostic impact of pulmonary-right ventricular (RV) uncoupling in patients with wild-type transthyretin amyloid cardiomyopathy (ATTRwt-CM).</p><p><strong>Methods and results: </strong>Among the 174 patients who were diagnosed with ATTRwt-CM at Kumamoto University Hospital from 2002 to 2021, 143 patients who met the current Japanese guideline and had sufficient information for two-dimensional speckle tracking echocardiography were retrospectively analysed. During a median follow-up of 1209 days, 39 cardiac deaths occurred. Compared with patients in the non-event group, those in the cardiac death group were significantly older (79.3 ± 6.7 vs. 76.4 ± 6.2, respectively; <i>P</i> < 0.05). Additionally, RV global longitudinal strain (RV-GLS)/systolic pulmonary artery pressure (sPAP), an index of pulmonary-RV uncoupling, was significantly lower in patients in the cardiac death group vs. the non-event group [0.29 (0.18-0.35) vs. 0.40 (0.29-0.57), <i>P</i> < 0.01]. Multivariate Cox proportional hazards regression analysis demonstrated that RV-GLS/sPAP was significantly associated with cardiac death after adjusting for tricuspid annular plane systolic excursion/sPAP (<i>P</i> < 0.01), sPAP (<i>P</i> < 0.05), and conventional prognostic factors including age and hospitalization for heart failure (<0.01), laboratory finding including high-sensitivity cardiac troponin T, and B-type natriuretic peptide (<i>P</i> < 0.01). Receiver operating characteristic analysis showed that the area under the curve for RV-GLS/sPAP for cardiac death was 0.72 and that the best cut off value for RV-GLS/sPAP was 0.34 (sensitivity, 76%; specificity, 65%). In the Kaplan-Meier analysis, patients with ATTRwt-CM who had low vs. high RV-GLS/sPAP (cut-off value 0.34) had a significantly higher probability of cardiac death (<i>P</i> < 0.01).</p><p><strong>Conclusion: </strong>Pulmonary-RV uncoupling has significantly higher prognostic value compared with conventional prognostic factors in ATTRwt-CM.</p>","PeriodicalId":94317,"journal":{"name":"European heart journal. Imaging methods and practice","volume":"3 1","pages":"qyae113"},"PeriodicalIF":0.0,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11740316/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143019457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Noninvasive assessment of myocardial perfusion using ultrafast ultrasound: clinical study for congenital heart disease.","authors":"Minh B Nguyen, Naiyuan Zhang, Luc L Mertens, David Barron, Osami Honjo, Maelys Venet, Jerome Baranger, Olivier Villemain","doi":"10.1093/ehjimp/qyaf007","DOIUrl":"10.1093/ehjimp/qyaf007","url":null,"abstract":"<p><strong>Aims: </strong>Myocardial perfusion impacts cardiac function following surgical repair of critical congenital heart disease (CCHD). Temporal variation assessment of myocardial blood volume throughout the cardiac cycle can be a surrogate for perfusion. Ultrafast power Doppler (UPD) is an ultrasound imaging technique capable of noninvasively quantifying myocardial blood volume changes. The objective of this study is to demonstrate the feasibility of perioperative transthoracic UPD assessment and to determine if UPD reflects physiologic changes in myocardial perfusion.</p><p><strong>Methods and results: </strong>Five neonatal transposition of the great arteries (TGA) undergoing arterial switch operation (ASO), five hypoplastic left heart syndrome (HLHS) undergoing Stage 1 palliation (S1P), and five age/weight-matched controls were prospectively recruited. Transthoracic UPD acquisitions were performed before/after operations. Segmental perfusion in right/left ventricles (RV/LV) was assessed. The controls' myocardial perfusion patterns are visually similar to published human references for both ventricles. Systolic/diastolic myocardial perfusion differences were modified by ASO in the RV (<i>P</i> = 0.03) but not for LV (<i>P</i> = 0.99). For HLHS patients, no difference after S1P was observed in either the RV (<i>P</i> = 0.16) nor the LV (<i>P</i> = 0.51).</p><p><strong>Conclusion: </strong>For TGA patients, the perfusion profile of the myocardium seems to be directly influenced by the intracavitary pressure (directly driving coronary perfusion pressure), namely if it was the systemic or sub-pulmonary ventricle. Our data suggests that UPD could noninvasively quantify myocardial perfusion variation. Myocardial perfusion patterns change in CCHD according to their haemodynamic and surgical status. Correlation with clinical outcomes requires further study.</p>","PeriodicalId":94317,"journal":{"name":"European heart journal. Imaging methods and practice","volume":"3 1","pages":"qyaf007"},"PeriodicalIF":0.0,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11837185/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143461472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Echocardiography of the right heart in pulmonary arterial hypertension: insights from the ULTRA RIGHT VALUE study.","authors":"Francesco Lo Giudice, Pilar Escribano-Subias, Khodr Tello, Grzegorz Kopec, Stefano Ghio, George Giannakoulas, Michele D'Alto, Domenico Filomena, Giovanna Manzi, Antonio Orlando, Alessandra Greco, Tommaso Recchioni, Selin Yildiz, Carmen Jiménez López-Guarch, Alejandro Cruz-Utrilla, Polykarpos Psochias, Vasiliki Patsiou, Jakub Stępniewski, Kamil Jonas, Laura Scelsi, Nils Kremer, Andrea Vergara, Carmine Dario Vizza, Robert Naeije, Roberto Badagliacca","doi":"10.1093/ehjimp/qyae121","DOIUrl":"https://doi.org/10.1093/ehjimp/qyae121","url":null,"abstract":"<p><strong>Aims: </strong>Outcome in pulmonary arterial hypertension (PAH) is determined by right ventricular (RV) function adaptation to increased afterload. Echocardiography is easily available to assist bedside evaluation of the RV. However, no agreement exists about the feasibility and most relevant measurements. We therefore examined the feasibility, quality, and clinical correlations of standard echocardiographic variables in the evaluation of PAH.</p><p><strong>Methods and results: </strong>The present multicentric study collected echocardiographic examinations with centralized reading in 401 patients with prevalent PAH. Clinical variables, as World Health Organization (WHO) functional class (FC), 6 min walk distance (6MWD), brain natriuretic peptide (BNP)/NT-proBNP, invasive haemodynamics, the European Society of Cardiology (ESC)/European Respiratory Society (ERS) guidelines-derived four-strata score, and the United States Registry to Evaluate Early and Long-Term Pulmonary Arterial Hypertension Disease Management (REVEAL) 2.0 score, were also collected. Echocardiographic measurements showed variable degrees of dilation of the right heart as assessed by right atrial and RV areas, altered indices of systolic function such as tricuspid annular plane systolic excursion (TAPSE), fractional area change, or 2D strain, and derived estimates of RV to pulmonary artery (PA) coupling by referring these measurements to systolic PA pressure (sPAP). All these measurements were feasible. All measurements of right heart dimensions and function, particularly TAPSE/sPAP, were correlated with WHO-FC, 6MWD, BNP/NT-proBNP, invasive haemodynamics, and ESC/ERS and REVEAL 2.0 scores.</p><p><strong>Conclusion: </strong>The present quality-controlled data from a network of PAH referral centres offer the background needed for further evaluation of the added value of echocardiography to currently recommended risk assessments in PAH.</p>","PeriodicalId":94317,"journal":{"name":"European heart journal. Imaging methods and practice","volume":"3 1","pages":"qyae121"},"PeriodicalIF":0.0,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11733976/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143019463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}