European heart journal. Imaging methods and practice最新文献

{"title":"Cardiac imaging highlights from European Society of Cardiology 2024: the future is within our grasp!","authors":"Stefano Figliozzi, Erika Hutt, Alessia Gimelli, Wael A Jaber","doi":"10.1093/ehjimp/qyaf009","DOIUrl":"10.1093/ehjimp/qyaf009","url":null,"abstract":"<p><p>The European Society of Cardiology has held its annual Congress in London, UK, from 30 August to 2 September 2024. With a total of 31 800 participants, 5400 faculty and presenters, and many National Cardiac Societies and industry partners, the Congress has taken an enormous step forward to present and discuss the latest advances in cardiovascular medicine. The sizable intercontinental reach was proved by the fact that 5 of the 10 top countries, in terms of submission of abstracts, were from outside Europe: China, the USA, Japan, Korea, and Australia. This brought a great impetus for international collaboration and exchange of views, learning from different perspectives. Specifically, the field of cardiovascular imaging has been in the spotlight, remarking its growing, central, and transversal role in modern cardiovascular medicine. In this communication, we offer a summary of some notable advances in research, either in terms of novelty or clinical applicability, within the realm of four imaging modalities: echocardiography, cardiovascular magnetic resonance, computed tomography, and nuclear imaging.</p>","PeriodicalId":94317,"journal":{"name":"European heart journal. Imaging methods and practice","volume":"3 1","pages":"qyaf009"},"PeriodicalIF":0.0,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11795670/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143257743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coronary complications in Kawasaki disease: giant aneurysms and thrombosis leading to myocardial infarction.","authors":"Jacobo Sebastián Vera-Chávez, Carlos Antonio Villegas-Chávez, Gabriela Meléndez-Ramírez, María Del Carmen López-Rodríguez, Karina Del Valle Zamora","doi":"10.1093/ehjimp/qyae116","DOIUrl":"https://doi.org/10.1093/ehjimp/qyae116","url":null,"abstract":"","PeriodicalId":94317,"journal":{"name":"European heart journal. Imaging methods and practice","volume":"3 1","pages":"qyae116"},"PeriodicalIF":0.0,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11740313/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143019460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical significance of the estimation of pulmonary-right ventricular uncoupling in patients with transthyretin amyloid cardiomyopathy.","authors":"Hiroki Usuku, Eiichiro Yamamoto, Kasumi Miyazaki, Ryudai Higashi, Atsushi Nozuhara, Fumi Oike, Naoto Kuyama, Noriaki Tabata, Masanobu Ishii, Shinsuke Hanatani, Tadashi Hoshiyama, Hisanori Kanazawa, Daisuke Sueta, Yuichiro Arima, Seitaro Oda, Hiroaki Kawano, Yasushi Matsuzawa, Yasuhiro Izumiya, Mitsuharu Ueda, Yasuhito Tanaka, Kenichi Tsujita","doi":"10.1093/ehjimp/qyae113","DOIUrl":"https://doi.org/10.1093/ehjimp/qyae113","url":null,"abstract":"<p><strong>Aims: </strong>There are few data on the prognostic impact of pulmonary-right ventricular (RV) uncoupling in patients with wild-type transthyretin amyloid cardiomyopathy (ATTRwt-CM).</p><p><strong>Methods and results: </strong>Among the 174 patients who were diagnosed with ATTRwt-CM at Kumamoto University Hospital from 2002 to 2021, 143 patients who met the current Japanese guideline and had sufficient information for two-dimensional speckle tracking echocardiography were retrospectively analysed. During a median follow-up of 1209 days, 39 cardiac deaths occurred. Compared with patients in the non-event group, those in the cardiac death group were significantly older (79.3 ± 6.7 vs. 76.4 ± 6.2, respectively; <i>P</i> < 0.05). Additionally, RV global longitudinal strain (RV-GLS)/systolic pulmonary artery pressure (sPAP), an index of pulmonary-RV uncoupling, was significantly lower in patients in the cardiac death group vs. the non-event group [0.29 (0.18-0.35) vs. 0.40 (0.29-0.57), <i>P</i> < 0.01]. Multivariate Cox proportional hazards regression analysis demonstrated that RV-GLS/sPAP was significantly associated with cardiac death after adjusting for tricuspid annular plane systolic excursion/sPAP (<i>P</i> < 0.01), sPAP (<i>P</i> < 0.05), and conventional prognostic factors including age and hospitalization for heart failure (<0.01), laboratory finding including high-sensitivity cardiac troponin T, and B-type natriuretic peptide (<i>P</i> < 0.01). Receiver operating characteristic analysis showed that the area under the curve for RV-GLS/sPAP for cardiac death was 0.72 and that the best cut off value for RV-GLS/sPAP was 0.34 (sensitivity, 76%; specificity, 65%). In the Kaplan-Meier analysis, patients with ATTRwt-CM who had low vs. high RV-GLS/sPAP (cut-off value 0.34) had a significantly higher probability of cardiac death (<i>P</i> < 0.01).</p><p><strong>Conclusion: </strong>Pulmonary-RV uncoupling has significantly higher prognostic value compared with conventional prognostic factors in ATTRwt-CM.</p>","PeriodicalId":94317,"journal":{"name":"European heart journal. Imaging methods and practice","volume":"3 1","pages":"qyae113"},"PeriodicalIF":0.0,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11740316/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143019457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Echocardiography of the right heart in pulmonary arterial hypertension: insights from the ULTRA RIGHT VALUE study.","authors":"Francesco Lo Giudice, Pilar Escribano-Subias, Khodr Tello, Grzegorz Kopec, Stefano Ghio, George Giannakoulas, Michele D'Alto, Domenico Filomena, Giovanna Manzi, Antonio Orlando, Alessandra Greco, Tommaso Recchioni, Selin Yildiz, Carmen Jiménez López-Guarch, Alejandro Cruz-Utrilla, Polykarpos Psochias, Vasiliki Patsiou, Jakub Stępniewski, Kamil Jonas, Laura Scelsi, Nils Kremer, Andrea Vergara, Carmine Dario Vizza, Robert Naeije, Roberto Badagliacca","doi":"10.1093/ehjimp/qyae121","DOIUrl":"https://doi.org/10.1093/ehjimp/qyae121","url":null,"abstract":"<p><strong>Aims: </strong>Outcome in pulmonary arterial hypertension (PAH) is determined by right ventricular (RV) function adaptation to increased afterload. Echocardiography is easily available to assist bedside evaluation of the RV. However, no agreement exists about the feasibility and most relevant measurements. We therefore examined the feasibility, quality, and clinical correlations of standard echocardiographic variables in the evaluation of PAH.</p><p><strong>Methods and results: </strong>The present multicentric study collected echocardiographic examinations with centralized reading in 401 patients with prevalent PAH. Clinical variables, as World Health Organization (WHO) functional class (FC), 6 min walk distance (6MWD), brain natriuretic peptide (BNP)/NT-proBNP, invasive haemodynamics, the European Society of Cardiology (ESC)/European Respiratory Society (ERS) guidelines-derived four-strata score, and the United States Registry to Evaluate Early and Long-Term Pulmonary Arterial Hypertension Disease Management (REVEAL) 2.0 score, were also collected. Echocardiographic measurements showed variable degrees of dilation of the right heart as assessed by right atrial and RV areas, altered indices of systolic function such as tricuspid annular plane systolic excursion (TAPSE), fractional area change, or 2D strain, and derived estimates of RV to pulmonary artery (PA) coupling by referring these measurements to systolic PA pressure (sPAP). All these measurements were feasible. All measurements of right heart dimensions and function, particularly TAPSE/sPAP, were correlated with WHO-FC, 6MWD, BNP/NT-proBNP, invasive haemodynamics, and ESC/ERS and REVEAL 2.0 scores.</p><p><strong>Conclusion: </strong>The present quality-controlled data from a network of PAH referral centres offer the background needed for further evaluation of the added value of echocardiography to currently recommended risk assessments in PAH.</p>","PeriodicalId":94317,"journal":{"name":"European heart journal. Imaging methods and practice","volume":"3 1","pages":"qyae121"},"PeriodicalIF":0.0,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11733976/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143019463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How to perform and evaluate a myocardial perfusion imaging by computed tomography.","authors":"Saima Mushtaq, Andrea Baggiano, Francesco Cannata, Alberico Del Torto, Fabio Fazzari, Laura Fusini, Daniele Junod, Riccardo Maragna, Luigi Tassetti, Alessandra Volpe, Nazario Carrabba, Edoardo Conte, Marco Guglielmo, Lucia La Mura, Valeria Pergola, Roberto Pedrinelli, Pasquale Perrone Filardi, Andrea Igoren Guaricci, Gianluca Pontone","doi":"10.1093/ehjimp/qyaf001","DOIUrl":"10.1093/ehjimp/qyaf001","url":null,"abstract":"<p><p>Stress computed tomography perfusion (CTP) delivers a comprehensive evaluation of both the anatomical and functional aspects in a single examination. It stands out as the only non-invasive technique capable of quantifying coronary stenosis and assessing its functional impact, offering a consolidated diagnostic and management approach for patients with confirmed or suspected coronary artery disease (CAD). This very practical review ('How to..' approach) provides guidance on conducting and interpreting static and dynamic CTP, along with an analysis of the strengths and limitations of these methodologies.</p>","PeriodicalId":94317,"journal":{"name":"European heart journal. Imaging methods and practice","volume":"3 1","pages":"qyaf001"},"PeriodicalIF":0.0,"publicationDate":"2025-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11745902/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143019467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprehensive 4D-flow cardiac magnetic resonance evaluation of the descending thoracic aorta in aortic regurgitation.","authors":"J Urmeneta Ulloa, A Álvarez Vázquez, V Martínez de Vega, L Martínez de Vega, C Andreu-Vázquez, I J Thuissard-Vasallo, M Recio Rodríguez, J A Cabrera","doi":"10.1093/ehjimp/qyaf002","DOIUrl":"10.1093/ehjimp/qyaf002","url":null,"abstract":"<p><strong>Aims: </strong>To assess the reproducibility of 4D-Flow cardiac magnetic resonance (CMR) parameters in the descending thoracic aorta-DTAo-(regurgitant fraction [RF], end-diastolic reverse flow [EDRF], and holodiastolic flow reversal [HDR]), and the relationship with RF in the sinotubular junction (STJ), and the left ventricular end-diastolic volume index (LVEDVI) in patients with chronic aortic regurgitation (AR).</p><p><strong>Methods and results: </strong>A descriptive study of these variables was conducted. A receiver operating characteristic curve was used to determine the optimal cut-off point. Thirty patients had severe AR (RF ≥ 30%, STJ) and 60 mild-to-moderate (RF < 30%). The mean age was 59 ± 17 years. Left ventricular ejection fraction (LVEF) was 56% (53-61%) and LVEDVI was 94 (76-128) mL/m². Flow in the DTAo at the left inferior pulmonary vein (LIPV) was easily identifiable and measurements were highly reproducible. The intraclass correlation coefficient was 0.969 (95% CI: 0.954-0.980) for RF and 0.929 (95% CI: 0.893-0.952) for EDRF. Flow parameters measured at the LIPV were all significantly greater in the severe AR group: RF (21% vs. 6%, <i>P</i> < 0.001), EDRF (20 vs. 4 mL/s; <i>P</i> < 0.001), and HDR (20% vs. 8%; <i>P</i> < 0.001). Three parameters-presence of HDR, RF ≥ 17%, and EDRF ≥ 7 mL/s at the LIPV-were associated with RF ≥ 30% in the STJ and elevated LVEDVI.</p><p><strong>Conclusion: </strong>4D-flow CMR can reproducibly assess flow in the DTAo in patients with chronic AR. An RF ≥ 17%, EDRF ≥ 7 mL/s, and/or the presence of HDR in the DTAo (LIPV) were associated with an RF ≥ 30% in STJ and elevated LVEDVI.</p>","PeriodicalId":94317,"journal":{"name":"European heart journal. Imaging methods and practice","volume":"3 1","pages":"qyaf002"},"PeriodicalIF":0.0,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11758371/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143049435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiac manifestations of autosomal dominant polycystic kidney disease.","authors":"Franja Dugar, Maurice Pradella, Arnheid Kessel-Schaefer, Paul Kettnaker, Philip Haaf","doi":"10.1093/ehjimp/qyaf003","DOIUrl":"https://doi.org/10.1093/ehjimp/qyaf003","url":null,"abstract":"","PeriodicalId":94317,"journal":{"name":"European heart journal. Imaging methods and practice","volume":"3 1","pages":"qyaf003"},"PeriodicalIF":0.0,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11756268/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143030689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>Ex vivo</i> imaging of subacute myocardial infarction with ultra-short echo time 3D quantitative T₁- and T_1<i>ρ</i> -mapping magnetic resonance imaging in mice.","authors":"Iida Räty, Antti Aarnio, Mikko J Nissi, Sanna Kettunen, Anna-Kaisa Ruotsalainen, Svetlana Laidinen, Seppo Ylä-Herttuala, Elias Ylä-Herttuala","doi":"10.1093/ehjimp/qyae131","DOIUrl":"10.1093/ehjimp/qyae131","url":null,"abstract":"<p><strong>Aims: </strong>The aim of this study was to develop an ultra-short echo time 3D magnetic resonance imaging (MRI) method for imaging subacute myocardial infarction (MI) quantitatively and in an accelerated way. Here, we present novel 3D T₁- and T_1<i>ρ</i> -weighted Multi-Band SWeep Imaging with Fourier Transform and Compressed Sensing (MB-SWIFT-CS) imaging of subacute MI in mice hearts <i>ex vivo</i>.</p><p><strong>Methods and results: </strong>Relaxation time-weighted and under-sampled 3D MB-SWIFT-CS MRI were tested with manganese chloride (MnCl₂) phantom and mice MI model. MI was induced in C57BL mice, and the hearts were collected 7 days after MI and then fixated. The hearts were imaged with T₁ and adiabatic T_1<i>ρ</i> relaxation time-weighted 3D MB-SWIFT-CS MRI, and the contrast-weighted image series were estimated with a locally low-rank regularized subspace constrained reconstruction. The quantitative parameter maps, T₁ and T_1<i>ρ</i> , were then obtained by performing non-linear least squares signal fitting on the image estimates. For comparison, the hearts were also imaged using 2D fast spin echo-based T₂ and T_1<i>ρ</i> mapping methods. The relaxation rates varied linearly with the MnCl₂ concentration, and the T₁ and T_1<i>ρ</i> relaxation time values were elevated in the damaged areas. The ischaemic areas could be observed visually in the 3D T₁, 3D T_1<i>ρ</i> , and 2D MRI maps. The scar tissue formation in the anterior wall of the left ventricle and inflammation in the septum were confirmed by histology, which is in line with the results of MRI.</p><p><strong>Conclusion: </strong>MI with early fibrosis, increased inflammatory activity, and interstitial oedema were determined simultaneously with T₁ and T_1<i>ρ</i> relaxation time constants within the myocardium by using the 3D MB-SWIFT-CS method, allowing quantitative isotropic 3D assessment of the entire myocardium.</p>","PeriodicalId":94317,"journal":{"name":"European heart journal. Imaging methods and practice","volume":"3 1","pages":"qyae131"},"PeriodicalIF":0.0,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11726772/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142985930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deep learning model to diagnose cardiac amyloidosis from haematoxylin/eosin-stained myocardial tissue.","authors":"Takeshi Tohyama, Takeshi Iwasaki, Masataka Ikeda, Masato Katsuki, Tatsuya Watanabe, Kayo Misumi, Keisuke Shinohara, Takeo Fujino, Toru Hashimoto, Shouji Matsushima, Tomomi Ide, Junji Kishimoto, Koji Todaka, Yoshinao Oda, Kohtaro Abe","doi":"10.1093/ehjimp/qyae141","DOIUrl":"10.1093/ehjimp/qyae141","url":null,"abstract":"<p><strong>Aims: </strong>Amyloid deposition in myocardial tissue is a definitive feature for diagnosing cardiac amyloidosis, though less invasive imaging modalities such as bone tracer cardiac scintigraphy and cardiac magnetic resonance imaging have been established as first steps for its diagnosis. This study aimed to develop a deep learning model to support the diagnosis of cardiac amyloidosis from haematoxylin/eosin (HE)-stained myocardial tissue.</p><p><strong>Methods and results: </strong>This single-centre retrospective observational study enrolled 166 patients who underwent myocardial biopsies between 2008 and 2022, including 76 patients diagnosed with cardiac amyloidosis and 90 with other diagnoses. A deep learning model was developed to output the probabilities of cardiac amyloidosis for all the small patches cutout from each myocardial specimen. The developed model highlighted the area in the stained images as highly suspicious, corresponding to where Dylon staining marked amyloid deposition, and discriminated the patches in the evaluation dataset with an area under the curve of 0.965. Provided that the diagnostic criterion for cardiac amyloidosis was defined as a median probability of cardiac amyloidosis >50% in all patches, the model achieved perfect performance in discriminating patients with cardiac amyloidosis from those without it, with an area under the curve of 1.0.</p><p><strong>Conclusion: </strong>A deep learning model was developed to diagnose cardiac amyloidosis from HE-stained myocardial tissue accurately. Although further prospective validation of this model using HE-stained myocardial tissues from multiple centres is needed, it may help minimize the risk of missing cardiac amyloidosis and maximize the utility of histological diagnosis in clinical practice.</p>","PeriodicalId":94317,"journal":{"name":"European heart journal. Imaging methods and practice","volume":"3 1","pages":"qyae141"},"PeriodicalIF":0.0,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11728699/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142985951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Haemodynamic and hyperaemic effects of adenosine in patients with atrial fibrillation undergoing quantitative myocardial perfusion cardiovascular magnetic resonance.","authors":"Simran Shergill, Charley A Budgeon, Mohamed Elshibly, Peter Kellman, Anvesha Singh, Gerry P McCann, Gaurav S Gulsin, J Ranjit Arnold","doi":"10.1093/ehjimp/qyae127","DOIUrl":"10.1093/ehjimp/qyae127","url":null,"abstract":"<p><strong>Aims: </strong>Patients with atrial fibrillation (AF) are thought to have an attenuated response to adenosine during vasodilator stress testing. We sought to investigate the haemodynamic and hyperaemic effects of adenosine in patients with AF undergoing adenosine-stress cardiovascular magnetic resonance (CMR) assessment.</p><p><strong>Methods and results: </strong>We retrospectively examined 318 patients referred for clinical adenosine-stress CMR (AF <i>n</i> = 158, sinus rhythm [SR] <i>n</i> = 160). Baseline and peak heart rate (HR) and quantitative myocardial perfusion were compared between groups. At peak stress, the haemodynamic response was blunted in patients with AF (HR increase 7 ± 10bpm vs. 17 ± 11bpm in SR, <i>P</i> < 0.001). Fewer patients in AF met the threshold for a satisfactory HR response ≥10bpm (40% in AF vs. 76% in SR, <i>P</i> < 0.001). There were no intergroup differences in hyperaemic myocardial blood flow (1.52 ± 0.65 mL/min/g in AF vs. 1.55 ± 0.65 mL/min/g in SR, <i>P</i> = 0.670) or myocardial perfusion reserve (2.66 ± 1.11 in AF vs. 2.66 ± 1.08 in SR, <i>P</i> = 0.981). AF (odds ratio [OR], 0.29 [0.17-0.50], <i>P</i> < 0.001) and left ventricular ejection fraction (OR 1.03 [1.00-1.05], <i>P</i> = 0.023) were independently associated with achieving a satisfactory HR response on multivariable analysis, but only ejection fraction (OR 1.05 [1.02-1.09], <i>P</i> = 0.003) predicted a satisfactory hyperaemic response.</p><p><strong>Conclusion: </strong>The heart rate response during adenosine-stress CMR is blunted in AF patients. Despite this, the majority of patients with AF generate a sufficient hyperaemic response with a standard adenosine-stress protocol. Further work is needed to determine the diagnostic accuracy of adenosine-stress CMR in patients with AF.</p>","PeriodicalId":94317,"journal":{"name":"European heart journal. Imaging methods and practice","volume":"2 3","pages":"qyae127"},"PeriodicalIF":0.0,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11670251/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142901542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}