European heart journal. Imaging methods and practice最新文献

{"title":"Speckle tracking echocardiography for prediction of arrhythmias in idiopathic ventricular fibrillation.","authors":"Rasmus B Dinesen, Ulrik Christian G Winsløw, Michael Vinther, Berit Th Philbert, Tor Biering-Sørensen, Niels Stampe, Bo G Winkel, Jacob Tfelt-Hansen, Niels Risum","doi":"10.1093/ehjimp/qyaf099","DOIUrl":"10.1093/ehjimp/qyaf099","url":null,"abstract":"<p><strong>Aims: </strong>Individuals experiencing a sudden cardiac arrest with ventricular fibrillation and no identifiable cause are diagnosed with idiopathic ventricular fibrillations (IVFs). 2D speckle tracking echocardiography (2DSTE) has been able to detect differences between IVF patients and controls. However, the association between these differences and the risk of ventricular arrhythmias (VAs) remains unknown.This study aimed to investigate whether parameters derived from myocardial deformation analysis using 2DSTE are associated with the recurrence of VA in IVF patients.</p><p><strong>Methods and results: </strong>This single-centre, cross-sectional study enrolled IVF patients treated with an implantable cardioverter defibrillator. IVF patients were compared with healthy sex- and age-matched controls. Furthermore, IVF patients were categorized into two groups (IVF patients with or without recurrent VA) based on the recurrence of VA over a 5-year follow-up period. Left ventricular global longitudinal strain (LVGLS) and left ventricular mechanical dispersion (LVMD) were investigated using 2DSTE and compared across all groups. Fifty-six IVF patients, males 39 (69.9%), age 49 ± 15 years, and 55 controls were included. IVF patients showed significantly increased LVMD (35.78 ± 13.4 ms vs. 31.0 ± 9.8 ms; <i>P</i> = 0.03) and decreased LVGLS (-18.8% ± 3.0% vs. -20.5% ± 2.7%; <i>P</i> < 0.01) compared with controls. IVF patients with recurrent VA had significantly increased LVMD compared with IVF patients without recurrent VA (43.63 ± 13.63 vs. 33.16 ± 12.45; <i>P</i> = 0.02).</p><p><strong>Conclusion: </strong>IVF patients had an increased LVMD and decreased LVGLS compared with healthy controls. Increased LVMD was significantly associated with recurrent VA in IVF patients suggesting a potential clinical value in risk stratification of VA recurrency in IVF patients.</p>","PeriodicalId":94317,"journal":{"name":"European heart journal. Imaging methods and practice","volume":"3 2","pages":"qyaf099"},"PeriodicalIF":0.0,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12344416/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144850195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aorta unveiled: the crucial role of imaging in diagnosing and managing aortic disease-a review.","authors":"Jean-Baptiste Ricco, Aurélien Hostalrich, Xavier Chaufour","doi":"10.1093/ehjimp/qyaf108","DOIUrl":"10.1093/ehjimp/qyaf108","url":null,"abstract":"<p><p>Aortic diseases, including aneurysmal and occlusive pathologies of the thoracic and abdominal aorta, represent a significant source of cardiovascular morbidity and mortality. This narrative review explores the role of modern and emerging imaging modalities in the management of aortic disease and highlights the pivotal roles of computed tomography angiography (CTA), magnetic resonance imaging (MRI), and contrast-enhanced ultrasound (CEUS). CTA remains the cornerstone for evaluating aneurysms, dissections, and traumatic injuries, offering high spatial resolution, rapid acquisition, and detailed anatomical assessment. MRI, particularly with advanced sequences such as 4D flow, provides comprehensive multiparametric evaluation without radiation exposure, making it ideal for younger patients and those requiring repeat imaging. Positron emission tomography (PET), especially when integrated with CTA or MRI, enables metabolic characterization of inflammation and infection in aortic walls. Ultrasound, particularly CEUS, remains indispensable in abdominal aortic aneurysm (AAA) screening and post-endovascular aortic aneurysm repair (EVAR) surveillance, especially in patients with renal impairment. Emerging technologies, including hybrid imaging, radiomics, and artificial intelligence (AI) are reshaping the landscape of aortic diagnostics. These innovations enhance detection of subtle imaging features, automate measurements, and may enable prediction of disease progression or complications.</p>","PeriodicalId":94317,"journal":{"name":"European heart journal. Imaging methods and practice","volume":"3 2","pages":"qyaf108"},"PeriodicalIF":0.0,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12448707/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145115843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"One-click co-registered T2 mapping and dual black- and bright-blood late gadolinium enhancement MRI for comprehensive assessment of myocardial injury after acute STEMI.","authors":"Aurelien Bustin, Victor de Villedon de Naide, Edouard Gerbaud, Thaïs Génisson, Kalvin Narceau, Théo Richard, Konstantinos Vlachos, Guido Caluori, Claire Bazin, Soumaya Sridi, Ilyes Benlala, Gael Dournes, Maxime Sermesant, Michel Montaudon, Pierre Jaïs, Matthias Stuber, Hubert Cochet","doi":"10.1093/ehjimp/qyaf103","DOIUrl":"10.1093/ehjimp/qyaf103","url":null,"abstract":"<p><strong>Aims: </strong>In acute ST-segment elevation myocardial infarction, ischaemia and reperfusion lead to a cascade of myocardial injury that can be characterized by cardiac magnetic resonance (CMR) imaging, including coagulation necrosis, oedema, papillary muscle damage, microvascular obstruction, and intramyocardial haemorrhage. Conventional CMR protocols require multiple sequences to be performed and complicated analysis. This study evaluates SPOT-MAPPING, a sequence that acquires co-registered T2 maps and dual bright- and black-blood late gadolinium enhancement (LGE) images in a single scan.</p><p><strong>Methods and results: </strong>SPOT-MAPPING employs a single-shot, ECG-triggered 2D sequence alternating between bright- and black-blood LGE imaging with varying T2 weightings. We prospectively enrolled 20 STEMI patients undergoing CMR at 1.5 T within 4-7 days post-emergent coronary intervention. SPOT-MAPPING's segmentation times and reproducibility of myocardial injury markers (oedema, scar size, transmurality, papillary muscle damage) were assessed against conventional T2 mapping and phase-sensitive inversion recovery (PSIR). SPOT-MAPPING halved left ventricular wall segmentation time (∼3 min) while maintaining high reproducibility for oedema, scar size, and transmurality (ICC > 0.8). It improved papillary muscle damage detection over PSIR (8 vs. 3 patients) and showed comparable T2 values with conventional T2 mapping (remote: 45.0 ± 3.6 ms vs. 45.9 ± 3.7 ms, <i>P</i> = 0.746; oedema: 67.6 ± 10.3 ms vs. 71.8 ± 8.6 ms, <i>P</i> = 0.373). Agreement with PSIR for scar quantification was strong (mean bias: volume +1.5 mL, size +2.9%, transmurality +2.8%). SPOT-MAPPING demonstrated higher inter- and intraobserver reproducibility for scar size as a percentage of oedema volume compared with PSIR combined with conventional T2 mapping (ICC = 0.98 vs. 0.89 and 0.93 vs. 0.85).</p><p><strong>Conclusion: </strong>SPOT-MAPPING offers a time-efficient and reproducible CMR method for myocardial injury assessment post-STEMI.</p>","PeriodicalId":94317,"journal":{"name":"European heart journal. Imaging methods and practice","volume":"3 2","pages":"qyaf103"},"PeriodicalIF":0.0,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12372463/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between left ventricular cavity size and transient ischaemic dilation ratio on dipyridamole stress single-photon emission computerized tomography myocardial perfusion imaging in a female Asian population.","authors":"Chun Hui Sharmaine Wong, Min Sen Yew","doi":"10.1093/ehjimp/qyaf102","DOIUrl":"10.1093/ehjimp/qyaf102","url":null,"abstract":"<p><strong>Aims: </strong>Single-photon emission computerized tomography (SPECT) myocardial perfusion imaging (MPI) has reduced accuracy in patients with small left ventricular (LV) size. Although transient ischaemic dilation (TID) is a sign of extensive coronary artery disease when accompanied by perfusion defects, its significance with normal perfusion remains unclear. We aim to study the relationship between the LV size and the TID ratio (TIDr) amongst females with normal SPECT MPI.</p><p><strong>Methods and results: </strong>Retrospective single-centre study of female patients with normal dipyridamole stress MPI, defined as the summed stress score = 0 with both stress and rest LV ejection fraction ≥50% on gated images. Small LV was defined as a gated rest end diastolic volume (EDV) below the 20th percentile of the study cohort. TIDr was derived using the quantitative perfusion SPECT software. There were 107 female patients (mean age-70) included. The threshold for small LV size was determined to be an EDV of <36.6 mL. Patients with or without small LV were similar in age, ethnicity, body mass index, and comorbidities. TIDr was significantly greater for patients with small LV (1.33 vs. 1.28, <i>P</i> = 0.042). There was a significant negative correlation between the resting EDV and the TIDr (<i>r</i> = -0.34, <i>P</i> < 0.001), which remained significant after controlling for age, body mass index, resting left ventricular ejection fraction, diabetes mellitus, and hypertension (<i>r</i> = -0.35, <i>P</i> < 0.001).</p><p><strong>Conclusion: </strong>In females with a normal dipyridamole stress SPECT MPI, TIDr is significantly higher in those with small LV. LV size should be considered when interpreting TID in females with otherwise normal MPI.</p>","PeriodicalId":94317,"journal":{"name":"European heart journal. Imaging methods and practice","volume":"3 2","pages":"qyaf102"},"PeriodicalIF":0.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12368955/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Real-world outcomes of TMVR-eligible and TMVR-ineligible patients.","authors":"Edoardo Zancanaro, Nicola Buzzatti, Nicolò Azzola Guicciardi, Paolo Denti, Eustachio Agricola, Francesco Ancona, Ottavio Alfieri, Michele De Bonis, Francesco Maisano, Roberto Lorusso","doi":"10.1093/ehjimp/qyaf098","DOIUrl":"https://doi.org/10.1093/ehjimp/qyaf098","url":null,"abstract":"<p><strong>Aims: </strong>Over the past decade, transcatheter valve replacement has emerged as a therapy for selected patients with valvular heart. Clinical experience with transcatheter mitral valve replacement (TMVR) has been limited to date and provides little insight into its potential as a viable therapy for MR. The present study aims to analyze the current longest follow-up real-life outcomes of TMVR procedures with a specific focus on the patient population left untreated due to the unfeasibility of the procedure.</p><p><strong>Results: </strong>Out of 3400 patients referred for mitral pathology, 88 were screened for TMVR procedure, being unfeasible for surgical and TEER procedure (Transcatheter Edge-to-Edge Repair). 37 pts (45%) were screened positive and treated with TMVR; 30 (81%) with Tendyne system (Abbott) and 7 (19%) with Tiara. For cardiac death, in TMVR the survival was 97.2%, 90.7%, and 90.7% at 1, 2, and 4 years, respectively. Concerning MT, instead, it was 86.4%, 77%, and 42% at 1, 2, and 4 years, respectively. A difference is seen between the two groups, <i>P</i>-value 0.024.</p><p><strong>Conclusion: </strong>TMVR is a valid option in selected patients and give valid longer follow-up results. The TMVR-ineligible patients showed a progressive detrimental worse survival across the follow-up.</p>","PeriodicalId":94317,"journal":{"name":"European heart journal. Imaging methods and practice","volume":"3 4","pages":"qyaf098"},"PeriodicalIF":0.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12499754/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145246149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MiR-132 inhibition improves myocardial strain in a large animal model of chronic left ventricular adverse remodelling.","authors":"Sandor Batkai, Andreas Spannbauer, Janika Viereck, Celina Genschel, Steffen Rump, Denise Traxler, Martin Riesenhuber, Dominika Lukovic, Katrin Zlabinger, Ena Hasimbegovic, Thomas Thum, Mariann Gyöngyösi","doi":"10.1093/ehjimp/qyaf088","DOIUrl":"10.1093/ehjimp/qyaf088","url":null,"abstract":"<p><strong>Aims: </strong>Cardiac miR-132 has been proposed as a target for heart failure (HF) therapy. CDR132L, a rationally designed synthetic oligonucleotide inhibitor of miR-132 has proved pre-clinical efficacy in non-ischaemic and ischaemic large animal HF models. The safety and tolerability of CDR132L were tested in chronic HF patients in a Phase 1b study (NCT04045405) and is currently being tested in a Phase 2 trial in post-MI HF patients (NCT05350969). The aim of the current study was to gain further data on myocardial function and efficacy of CDR132L by analysing left ventricular (LV) and atrial (LA) wall motion by serial cardiac magnetic resonance (cMRI) strain imaging in a clinically relevant large animal (pig) model of chronic HF.</p><p><strong>Methods and results: </strong>Animals (15 per group) were randomized 1-month post-MI and received five intravenous (i.v.) monthly treatments with CDR132L (5 mg/kg) or placebo and were followed up for 6-month post-MI. LV and LA strain parameters were deteriorated after MI over time but significantly ameliorated by CDR132L treatment, compared with placebo. Strain parameters showed significant correlations with pharmacodynamic measures such as ejection fraction, NT-proBNP, and cardiac interstitial fibrosis in remodelling hearts 6 months post-MI.</p><p><strong>Conclusion: </strong>LV and LA motion and contractility were improved by repeated monthly dosing of CDR132L in a large animal model of HF with reduced ejection fraction model with first dose given one month post-MI. The results highlight the translational value and usability of MRI-based cardiac strain imaging in HF drug development and support further clinical development of CDR132L.</p>","PeriodicalId":94317,"journal":{"name":"European heart journal. Imaging methods and practice","volume":"3 2","pages":"qyaf088"},"PeriodicalIF":0.0,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12318716/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144786345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Partial prosthesis detachment early after open atrial transcatheter mitral valve replacement: could an artificial intelligence-based modified mitral valve model make the difference?","authors":"Aureliano Ruggio, Gabriella Locorotondo, Andrea Campea, Riccardo Marano, Eleonora Moliterno, Francesca Graziani, Cristina Aurigemma, Faustino Pennestrì, Antonella Lombardo, Francesco Burzotta","doi":"10.1093/ehjimp/qyaf096","DOIUrl":"https://doi.org/10.1093/ehjimp/qyaf096","url":null,"abstract":"","PeriodicalId":94317,"journal":{"name":"European heart journal. Imaging methods and practice","volume":"3 2","pages":"qyaf096"},"PeriodicalIF":0.0,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12343099/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144839655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Haemodynamic implications of cardiovascular magnetic resonance pulmonary capillary wedge pressure in acute myocardial infarction.","authors":"Pankaj Garg, Aradhai Bana, Gareth Matthews, Tiya Bali, Rui Li, Zia Mehmood, Liang Zhong, Rob J van der Geest, Sven Plein, John P Greenwood, Peter Swoboda","doi":"10.1093/ehjimp/qyaf086","DOIUrl":"10.1093/ehjimp/qyaf086","url":null,"abstract":"<p><strong>Aims: </strong>Cardiovascular magnetic resonance (CMR)-derived pulmonary capillary wedge pressure (PCWP) has demonstrated diagnostic and prognostic utility in heart failure patients. However, its clinical value in acute myocardial infarction (AMI) remains undetermined. This study investigates the relationship between CMR-derived PCWP, myocardial injury, and left ventricular (LV) remodelling in re-perfused acute ST-elevation myocardial infarction (STEMI).</p><p><strong>Methods and results: </strong>Sixty-nine patients with STEMI underwent CMR within 48 h and at 3 months. PCWP was estimated using the sex-specific equation: CMR PCWP: 5.7591 + (0.07505 × left atrial volume) [0.05289 × left ventricular mass (LVM)] - (1.9927 × sex) [female = 0; male = 1], where LAV is left atrial volume (mL) and LVM is left ventricular mass (g). LV remodelling was assessed via changes in LV end-diastolic volume (LVEDV) and ejection fraction (LVEF). Patients with high CMR PCWP (≥18 mmHg) exhibited greater myocardial scar burden (28.5% vs. 17.2%, <i>P</i> = 0.0008) and microvascular obstruction (7.6% vs. 2.5%, <i>P</i> < 0.0001). They also had higher acute LVEDV (193.7 ± 39.7 vs. 158.0 ± 29.5 mL, <i>P</i> < 0.0001) and lower LVEF (41.4 ± 10.4% vs. 48.5 ± 9.2%, <i>P</i> = 0.0066). At follow-up, higher baseline CMR PCWP was associated with greater LV remodelling (<i>P</i> < 0.0001) and persistently reduced LVEF (45.4 ± 10.2% vs. 55.0 ± 10.3%, <i>P</i> = 0.0005). Regression analysis confirmed baseline PCWP as an independent predictor of follow-up LVEF (<i>P</i> = 0.0036).</p><p><strong>Conclusion: </strong>CMR-derived PCWP may be a valuable biomarker in STEMI, identifying patients at risk of adverse remodelling and LV dysfunction. Its integration into clinical practice may enhance risk stratification and guide targeted therapies.</p>","PeriodicalId":94317,"journal":{"name":"European heart journal. Imaging methods and practice","volume":"3 2","pages":"qyaf086"},"PeriodicalIF":0.0,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12311366/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144762943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Echocardiographic measurement of inferior vena cava diameter for estimating central venous pressure in adult Fontan patients.","authors":"Makoto Miyake, Hiraku Doi, Yu Noguchi, Kyokun Uehara, Toshihiro Tamura","doi":"10.1093/ehjimp/qyaf089","DOIUrl":"10.1093/ehjimp/qyaf089","url":null,"abstract":"<p><strong>Aims: </strong>In adult Fontan patients, a higher central venous pressure (CVP) is associated with worse clinical outcomes. Assessing CVP is helpful to guide therapeutic strategies; however, it remains unclear whether CVP can be accurately estimated from the inferior vena cava (IVC) diameter by echocardiography.</p><p><strong>Methods and results: </strong>This single-centre, retrospective study enrolled 21 adult Fontan patients (median age: 21.5 years, 52% male) who had a transthoracic echocardiogram performed after admission for a scheduled cardiac catheterization. The relationship between CVP estimated by echocardiography and CVP measured by catheterization was investigated. According to echocardiographic guidelines, CVP was estimated to be 3, 8, or 15 mmHg on the basis of the IVC diameter and its respiratory collapse. To evaluate the agreement between estimated and measured CVP grades, measured CVP was also classified into three grades. The mean IVC diameter and measured CVP were 1.41 ± 0.27 cm and 11.9 ± 2.8 mmHg, respectively. Both the IVC diameter and the estimated CVP grade were correlated with measured CVP (<i>r</i> = 0.526, <i>P</i> = 0.014 and rho = 0.573, <i>P</i> = 0.007, respectively). However, the estimated CVP grade was concordant with the measured CVP grade in only two patients. In the remaining 19 patients (90%), the estimated CVP grade was lower than the measured CVP grade. Only slight agreement was observed between these two gradings of CVP [weighted kappa coefficient: 0.13, 95% confidence interval (CI): 0.00-0.25].</p><p><strong>Conclusion: </strong>In adult Fontan patients, the echocardiographic classification of CVP grading using the IVC diameter may underestimate CVP, suggesting that this echocardiographic method cannot replace invasive methods in accurately assessing CVP.</p>","PeriodicalId":94317,"journal":{"name":"European heart journal. Imaging methods and practice","volume":"3 3","pages":"qyaf089"},"PeriodicalIF":0.0,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12360295/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144884784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Real-time guidance and automated measurements using deep learning to improve echocardiographic assessment of left ventricular size and function.","authors":"Sigbjorn Sabo, Håkon Pettersen, Gunn C Bøen, Even O Jakobsen, Per K Langøy, Hans O Nilsen, David Pasdeloup, Erik Smistad, Andreas Østvik, Lasse Løvstakken, Stian Stølen, Bjørnar Grenne, Håvard Dalen, Espen Holte","doi":"10.1093/ehjimp/qyaf094","DOIUrl":"10.1093/ehjimp/qyaf094","url":null,"abstract":"<p><strong>Aims: </strong>The low reproducibility of echocardiographic measurements challenges the identification of subtle changes in left ventricular (LV) function. Deep learning (DL) methods enable real-time analysis of acquisitions and may improve echocardiography. The aim of this study was to evaluate the impact of DL-based guidance and automated measurements on the reproducibility of LV global longitudinal strain (GLS), end-diastolic (EDV) and end-systolic (ESV) volume, and ejection fraction (EF).</p><p><strong>Methods and results: </strong>Forty-six patients (24 breast cancer and 22 general cardiology patients) were included and underwent four consecutive echocardiograms. Six were included twice, totalling 52 inclusions and 208 echocardiograms. One sonographer-cardiologist pair used DL guidance and measurements (DL group), while another did not use DL tools and performed manual measurements (manual group). DL group recordings were also measured using a commercially available DL-based EF tool. For GLS, the DL group had a 30% lower test-retest variability than the manual group (minimal detectable change 2.0 vs. 2.9, <i>P</i> = 0.036). LV volumes had ∼40% lower minimal detectable changes in the DL group vs. the manual group (32 mL vs. 52 mL for EDV and 18 mL vs. 32 mL for ESV, <i>P</i> ≤ 0.006). This did not translate to a significant improvement in EF reproducibility in the DL group. The benchmarking method showed similar results compared with the manual group.</p><p><strong>Conclusion: </strong>Combining real-time DL guidance with automated measurements improved the reproducibility of LV size and function measurements compared with usual care, but future studies are needed to evaluate its clinical effect.</p><p><strong>Trial registration number: </strong>NCT06310330.</p>","PeriodicalId":94317,"journal":{"name":"European heart journal. Imaging methods and practice","volume":"3 2","pages":"qyaf094"},"PeriodicalIF":0.0,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12311362/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144762944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}