Asian journal of neurosurgery最新文献

{"title":"What Is the Suitable Wide Cage Size for Stand-alone LLIF in Asian Population: A Computed Tomography Scan-Based Study of a Dimension of Lumbar Endplate.","authors":"Tinnakorn Pluemvitayaporn, Sahapap Tadee, Sombat Kunakornsawat, Suttinont Surapuchong, Warot Ratanakoosakul, Kijapat Tiracharnvut, Pritsanai Pruttikul, Chaiwat Piyasakulkaew, Piyabuth Kittithamvongs","doi":"10.1055/s-0044-1796668","DOIUrl":"10.1055/s-0044-1796668","url":null,"abstract":"<p><p><b>Objective</b>  The objective of this study is to establish a precise database detailing the width of vertebral endplates, the depth of vertebral endplates (anterior-posterior [A-P] width), and the height of intervertebral discs within the lumbar spine of the Asian population. <b>Materials and Methods</b>  The stand-alone lateral lumbar interbody fusion (LLIF) procedure is increasingly popular for minimally invasive spine surgery and has demonstrated effectiveness in treating various spinal pathologies. Previous studies have indicated that the use of a 26-mm wide cage in stand-alone LLIF can significantly decrease the incidence of cage subsidence. However, most of these studies were conducted on the Caucasian population, which has a larger anatomical structure compared with the Asian population. Consequently, the appropriate wide cage size suitable for stand-alone LLIF in the Asian population has not been previously explored. Ninety-one computed tomography (CT) images were obtained from patients who presented with back pain and had negative imaging results between 2017 and 2021. These images were analyzed using the Picture Archiving Communication System to assess the vertebral body's topography. The analysis involved measuring the vertebral endplate width, vertebral endplate depth (A-P width), and intervertebral disc height. <b>Results</b>  The findings of this study reveal that there is a noticeable increase in the overall width, depth, and intervertebral disc height of the lumbar vertebrae from the upper to the lower regions. Additionally, the morphometric attributes of the lumbar vertebrae observed in this study closely resemble those of Caucasian subjects. <b>Conclusion</b>  The morphometric measurements of the lumbar vertebrae in the Asian population closely resemble those of Caucasian subjects. As a result, it is suggested that a 26-mm wide cage may be a suitable option for stand-alone LLIF in the Asian population.</p>","PeriodicalId":94300,"journal":{"name":"Asian journal of neurosurgery","volume":"20 1","pages":"119-125"},"PeriodicalIF":0.0,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11875720/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143559751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"White Matter Dissection: Lessons from the United Kingdom National Neuroanatomy Undergraduate Competition 2023.","authors":"Ameerah Gardee, Eranga Goonewardena, Sytske Lub, Mohammad Ashraf, Hassan Ismahel, Attika Chaudhary, Laulwa Nasser Al-Salloum, Scott Border","doi":"10.1055/s-0044-1796649","DOIUrl":"10.1055/s-0044-1796649","url":null,"abstract":"<p><p><b>Objective</b>  This narrative highlights a student-led initiative that explored white matter dissection techniques within the framework of the National Undergraduate Neuroanatomy Competition 2023. <b>Materials and Methods</b>  The project aimed to enhance neuroanatomical education by developing a novel approach to dissection that deviates from the traditional Klingler's method. Instead, it incorporated contemporary techniques, including diffusion tensor imaging and other radiological tools, to ensure greater anatomical precision and enrich the learning experience. <b>Results</b>  The dissections focused on key white matter structures, such as the uncinate fasciculus and the inferior longitudinal fasciculus, and outlined a step-by-step methodology for creating high-quality specimens. These specimens are designed to serve as educational resources, particularly for students with limited access to formal neuroanatomy courses. <b>Conclusion</b>  This study emphasizes the critical role of hands-on dissection in neuroanatomy education, showcasing its ability to enhance student engagement, deepen anatomical understanding, and inspire interest in clinical neuroscience careers. By introducing innovative educational tools and methodologies, this initiative makes a meaningful contribution to addressing the issue of \"neurophobia\" in medical education.</p>","PeriodicalId":94300,"journal":{"name":"Asian journal of neurosurgery","volume":"20 1","pages":"95-104"},"PeriodicalIF":0.0,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11875721/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143559752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Outcome and Surgical Outcome of Moyamoya Disease after Combined Revascularization Performed at the Neurological Institute of Thailand.","authors":"Sarunya Yuthagovit, Punjama Lertbutsayanuku, Wuttipong Tirakotai","doi":"10.1055/s-0044-1792159","DOIUrl":"10.1055/s-0044-1792159","url":null,"abstract":"<p><p><b>Objective</b>  Moyamoya disease is a chronic, progressive, intracranial steno-occlusive disease. Cerebral revascularization has proved that it is more beneficial than medical therapy for prevention of recurrent stroke. We aimed to report clinical and surgical outcome of moyamoya disease after combined revascularization in Thai population. <b>Materials and Methods</b>  From October 2015 to March 2023, patients diagnosed with moyamoya disease and were operated with combined revascularization were included. Patients were evaluated for hemodynamic state with preoperative and postoperative blood oxygenation level-dependent magnetic resonance (BOLD MR) imaging. Demographic data, serial imaging, surgical outcome, and clinical outcome were analyzed. Morbidity and mortality rates of surgery were reported. For clinical outcome evaluation, modified Rankin Scale (mRS) scores were compared between preoperative and postoperative outcome. The mRS score of 0 to 2 signify good outcome after surgery. <b>Results</b>  There were a total of 55 patients. Ischemic stroke was the most common presentation (87.3%). Based on the Suzuki's classification, most of the patients were stage 3 and 4. Clinical outcome measured with mRS score had good outcome, 100% (mRS score 0-2). For surgical outcome, overall graft patency was 94.8%, overall complication rate was 6.5%, and mortality rate was zero. Mean follow-up duration was 44.5 ± 25.1 months. Recurrent stroke occurred in 1.3%, which was recurrent ischemic stroke. <b>Conclusion</b>  Combined revascularization in moyamoya disease in the Thai population has a good clinical outcome, an acceptable risk of complication, and a reduced recurrent rate of stroke. Clinical and surgical outcome should be studied in the long term with the use of BOLD MR with carbon dioxide stimuli for the evaluation of cerebral blood flow in the patient.</p>","PeriodicalId":94300,"journal":{"name":"Asian journal of neurosurgery","volume":"20 1","pages":"75-81"},"PeriodicalIF":0.0,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11875710/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143560509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endovascular Approach to Concurrent Anterior Cranial Fossa Dural AVF and Concurrent Flow-Related Ophthalmic Artery Aneurysm: A Case Study.","authors":"Vikas Chandra Jha, Rahul Jain, Vivek Saran Sinha, Nitish Kumar, Gaurav Verma, Sangam Jha","doi":"10.1055/s-0044-1792162","DOIUrl":"10.1055/s-0044-1792162","url":null,"abstract":"<p><p>Dural arteriovenous fistulas (DAVFs) with concurrent flow-related ophthalmic artery aneurysms, particularly intraorbital aneurysms, are rare. Retrograde cortical blood flow and sinus thrombosis heighten the risk of rupture and optic nerve compression, yet treatment strategies remain poorly defined. This study aims to explore effective management for these complex cases. A 66-year-old hypertensive man presented with an acute severe headache, loss of consciousness, and decreased vision in the left eye. Imaging revealed a left frontal intracranial hemorrhage and an anterior cranial fossa DAVF with a left ophthalmic artery aneurysm. Endovascular embolization via the left ophthalmic artery, using a microcatheter distal to the aneurysm and controlled reflux of glue injection (N-butyl cyanoacrylate and lipiodol), successfully treated the DAVF and ophthalmic artery aneurysm. Visual acuity improved to finger counting at 1 foot, with no residual DAVF at 6 months. This case demonstrates that controlled glue embolization is a viable alternative when microsurgery is not feasible due to complex anatomy.</p>","PeriodicalId":94300,"journal":{"name":"Asian journal of neurosurgery","volume":"20 1","pages":"183-189"},"PeriodicalIF":0.0,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11875697/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143560516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Should Not Children with Ventriculoatrial Shunts Be Taking Aspirin? An Update: 0% Distal Malfunction.","authors":"Suhas Udayakumaran, Shine Kumar","doi":"10.1055/s-0044-1795165","DOIUrl":"10.1055/s-0044-1795165","url":null,"abstract":"<p><p><b>Background</b>  Ventriculoatrial (VA) shunts have the potential to preserve life in the event of failure of ventriculoperitoneal (VP) shunts. Contrary to VP shunts, they are susceptible to consequences, particularly cardiac problems. There are no established guidelines for screening patients following VA shunt placement regarding prevention, anticoagulant treatment, or risk factor screening. <b>Objective</b>  We aim to investigate aspirin's potential function and effectiveness in enhancing shunt survival and preventing secondary morbidity from distal thrombosis in children with VA shunts. <b>Materials and Methods</b>  The study's design is prospective and observational. It began in 2011 and is ongoing. Before inclusion in the study, we obtained clearance from the hospital ethics board and consent from the family. All patients with VA shunts were given a once-a-day antiplatelet dose of 5 mg/kg of aspirin from the first postoperative day. The study's primary end points include: (1) Major distal end malfunction documented on echocardiography or (2) any cardiac complications directly associated with the VA shunt. <b>Results</b>  Since March 2011, 13 patients have been followed up. So far, no cardiac complications have been ascribed to VA shunts in any of the patients. The current follow-up period is 28 to 170 months. Patient follow-up is continuing. <b>Conclusion</b>  Our observations regarding the efficacy and safety of aspirin in VA shunts are encouraging. However, sufficient time would be needed to establish its effectiveness in chronic sequelae such as pulmonary hypertension.</p>","PeriodicalId":94300,"journal":{"name":"Asian journal of neurosurgery","volume":"20 1","pages":"88-94"},"PeriodicalIF":0.0,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11875709/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143560564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bone Mineral Density Distribution in the Posterior Wall of the Lateral Mass Evaluated by Computed Tomography Osteoabsorptiometry.","authors":"Kazuma Doi, Nozomu Inoue, Satoshi Tani, Junichi Mizuno","doi":"10.1055/s-0044-1793929","DOIUrl":"10.1055/s-0044-1793929","url":null,"abstract":"<p><p><b>Objective</b>  Cervical open-door laminoplasty using plates and miniscrews is gaining popularity. One of the complications of this procedure is the loosening or back-out of the miniscrews inserted in the lateral mass (LM). Bone mineral density (BMD) measured by computed tomography (CT) has been used as a predictor of bone strength. However, bone density distribution in the LM remains unclear. <b>Materials and Methods</b>  We investigated bone density distribution in the posterior wall of the LM. A total of 120 LMs were analyzed from the patients who underwent laminoplasty. The distribution of BMD defined by Hounsfield unit (HU) in the posterior wall of the LM was measured by CT osteoabsorptiometry. The posterior wall was divided into nine zones, which consisted of three columns (lateral, center, and medial) and three rows (cranial, center, and caudal). BMD in each zone was averaged and compared by zones and cervical levels. <b>Results</b>  Overall mean ± standard deviation BMD was 1,092 ± 433 HU. Averaged BMD in the entire posterior wall was highest at C4 (1,365 ± 459 HU), second highest at C3 (1,239 ± 435 HU), and lower in the lower levels. BMD in the medial-center zone (1,357 ± 443 HU) was the highest in all zones. BMD in the medial-caudal region at C7 was only 59% of the highest BMD in the medial-center region at C4. <b>Conclusion</b>  The medial-center to the cranial region was most suitable for miniscrew fixation for laminoplasty. These biomechanical findings would be useful in the preoperative planning of laminoplasty especially for the determination of the LM screw entry points and in the design of laminoplasty implants.</p>","PeriodicalId":94300,"journal":{"name":"Asian journal of neurosurgery","volume":"20 1","pages":"82-87"},"PeriodicalIF":0.0,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11875701/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143560539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Symptomatic Severe Stenosis of Cavernous Internal Carotid Artery Stenting: A Case Report with Short Literature Review.","authors":"Mohan Karki, Girish Rajpal","doi":"10.1055/s-0044-1792161","DOIUrl":"10.1055/s-0044-1792161","url":null,"abstract":"<p><p>Intracranial internal carotid artery (ICA) stenosis is rarely reported as compared with extracranial ICA stenosis. Atherosclerosis is one of the major beginnings of stenosis of vasculatures, which may lead to ischemic stroke causing morbidity and mortality. We report the case of a 60 -year-old man presented to us with complaints of multiple episodes of dizziness, mild headache, and transient left arm weakness for 3 months and had history of smoking, hypercholesterolemia (high level of low-density lipoprotein level = 220 mg/dL), diabetes mellitus, and hypertension under medication. No neurological deficits were observed at the time of admission. Patient underwent angioplasty and stenting with drug-eluting balloon-expandable coronary stent. Patient was discharged well at the 3rd day of procedure. No recurrence of stroke and restenosis were noted till 3 months of follow-up period. Stenting following angioplasty for treatment of symptomatic severe cavernous ICA stenosis with everolimus-eluting coronary balloon-expandable stent, Xience Xpedition, is safe and effective.</p>","PeriodicalId":94300,"journal":{"name":"Asian journal of neurosurgery","volume":"20 1","pages":"179-182"},"PeriodicalIF":0.0,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11875699/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143560566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Unusual Case of Alarming Lactic Acidosis: Brain Metabolic Cross-Talk.","authors":"Sivakumar R, Sumit Roy Chowdhury, Karma Ongmu Bhutia, Suman Sokhal","doi":"10.1055/s-0044-1791999","DOIUrl":"10.1055/s-0044-1791999","url":null,"abstract":"<p><p>A 39-year-old male with a BMI of 30.8 kg/m ² and a normal medical history underwent excision of a left orbito-cavernal hemangioma (4 × 2 × 2 cm) under general anesthesia. Balanced anesthesia and fluid management guided by pulse pressure variation (kept below 12%) were employed. Despite stable hemodynamics and normal blood sugar levels, arterial blood gas (ABG) analysis revealed a progressive rise in lactate levels, reaching 10.6 mmol/L, accompanied by acidemia. Systemic hypoperfusion was ruled out by maintaining mean arterial pressure between 70-80 mm Hg, ensuring a capillary refill time of less than 3 seconds, and confirming a central venous oxygen saturation of 72%. With a total blood loss of 800 mL, one unit of packed red blood cells was transfused due to concerns about decreased microcirculation and tissue hypoxia. After 10 hours of surgery, sodium bicarbonate (NaHCO3) was administered to mitigate metabolic acidosis and its potential impact on intracranial pressure. Postoperatively, lactate levels remained elevated (8-9 mmol/L), but with continued NaHCO3 infusion, lactate reduced to 6.4 mmol/L, allowing extubation. The patient's lactate normalized by the evening, and recovery was uneventful. This case highlights the significant metabolic disturbances, particularly lactic acidosis, that can arise during brain tumor surgery due to prolonged operative times, large tumor size, higher BMI, and stress-induced metabolic derangements. Awareness and prompt management of these disturbances are crucial for successful patient outcomes.</p>","PeriodicalId":94300,"journal":{"name":"Asian journal of neurosurgery","volume":"20 1","pages":"196-198"},"PeriodicalIF":0.0,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11875693/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143560537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Non-Neoformans Cryptococcal Infections in the Post-Coronavirus Disease-19 (COVID-19) Era: Are We Ready to Face the Emerging Challenge?","authors":"Umayra Fatima, Hina Ahmed, Gautam Singh, K Y Giri, Md Sania Azmi, Archana Meenakshi, Suresh Babu Jandrajupalli, Swarnalatha Chandolu, Abhishek Singh Nayyar","doi":"10.1055/s-0044-1791998","DOIUrl":"10.1055/s-0044-1791998","url":null,"abstract":"<p><p>Coronaviruses are a large group of viruses that infect animals as well as humans, while it is also suggested that, rarely, coronaviruses that infect animals can evolve and infect humans. Current evidence suggests that severe acute respiratory syndrome (SARS) coronavirus-2 leads to coronavirus disease-19 (COVID-19), the respiratory illness responsible for COVID-19 pandemic, while it has a zoonotic origin, closely related to the bat-origin SARS-like coronavirus. Also, as per the current knowledge, the disease may induce significant and persistent lymphopenia which in turn may increase the risk for various opportunistic infections. <i>Cryptococcus laurentii</i> is one such rare, but serious fungal infection which has been reported in post-COVID-19 disease and is a rising cause of concern since it can turn out to be fatal. The infection is caused by a non-neoformans rare human pathogen. The present case report describes the case of a 45-years old male patient who reported to the Outpatient Department (OPD) for a routine dental complaint with a grossly destructed tooth in left lower back tooth region due to extensive carious involvement, while, simultaneously, presenting with fever since 5 days in the post-COVID-19 phase, and was later diagnosed as being positive for <i>C. laurentii</i> infection on urine culture sensitivity test.</p>","PeriodicalId":94300,"journal":{"name":"Asian journal of neurosurgery","volume":"20 1","pages":"190-195"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11875713/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143560560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bow-Hunter Syndrome Due to Tandem Lesions; A Case Report.","authors":"Shigeomi Yokoya, Jun Nakauchi, Hidesato Takezawa","doi":"10.1055/s-0044-1792160","DOIUrl":"10.1055/s-0044-1792160","url":null,"abstract":"<p><p>Bow-Hunter syndrome (BHS) includes a form of stroke caused by dynamic factors affecting the extracranial vertebral artery (VA), such as rotation-induced flow disturbance at the atlantoaxial level. BHS is a rare condition that can result from a variety of factors, including abnormal bone compression and vertebral instability. So far, there have been no reports in which both vertebral instability and osteophytes compress the VA at different sites, leading to stroke. Herein, we present a rare case of stroke attributed to BHS involving thrombosis formation due to osteophyte compression at C3/4 and VA occlusion due to vertebral instability at the C4/5 overlapped. A 72-year-old male presented with rotational vertigo and vomiting associated with a cerebellar infarction. Digital subtraction angiography revealed severe stenosis of the left VA with an intra-arterial thrombus. Percutaneous transluminal angioplasty improved the stenosis; however, intravascular ultrasound revealed compression of the VA by osteophytes at C3/4. Additionally, left VA occlusion at C4/5 was confirmed because of vertebral instability. The osteophyte was removed via the anterolateral approach, and the VA was decompressed. The patient's postoperative course was uneventful, with no recurrence for more than 2 years. BHS can occur in the lower cervical spine when vertebral instability coincides with intimal arterial damage caused by osteophytes at other sites.</p>","PeriodicalId":94300,"journal":{"name":"Asian journal of neurosurgery","volume":"20 1","pages":"174-178"},"PeriodicalIF":0.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11875694/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143560541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}