{"title":"Sheep Head Cadaveric Model for the Transmeatal Extensions of the Retrosigmoid Approach.","authors":"Dmitriy Sergeyevich Korotkov, Alexander Feliciano Paitán, Arevik Abramyan, Feres Eduardo Aparecido Chaddad Neto","doi":"10.1055/s-0044-1790517","DOIUrl":"10.1055/s-0044-1790517","url":null,"abstract":"<p><p>The transmeatal extension of the retrosigmoid approach is an important procedure used in the treatment of various pathologies affecting the posterior fossa, petroclival region, and jugular foramen. Mastering this technique requires a high level of manual skill, particularly in temporal bone drilling. The objective of this study was to describe an easily accessible and cost-effective model of the transmeatal extension of the retrosigmoid approach using cadaveric sheep heads. Five cadaveric sheep heads, fixed in alcohol and formalin with intravascular-colored silicone injection, were prepared for this study. Two heads (four sides) were designated for illustrative anatomical specimens, while three heads (six sides) were used for surgical simulation. Additionally, one head was used to prepare and dissect a dry skull. All critical steps of the transmeatal approach, including both supra- and inframeatal extensions, were successfully replicated on the model. A comparative anatomical analysis was conducted, focusing on the technical nuances of the model. The cadaveric sheep head serves as an effective model for the retrosigmoid approach with transmeatal extensions, primarily for training manual haptic skills. While the sheep model cannot precisely replicate human anatomy, it still offers valuable training opportunities for neurosurgeons, particularly when human cadaveric specimens are unavailable.</p>","PeriodicalId":94300,"journal":{"name":"Asian journal of neurosurgery","volume":"19 4","pages":"791-804"},"PeriodicalIF":0.0,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588626/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142741944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alex T Johnson, Ganesh Kumar, Bibhudendu Mohapatra, Rajat Mahajan
{"title":"Perioperative Complications of Oblique Lumbar Interbody Fusion (OLIF): 5 Years of Experience with OLIF.","authors":"Alex T Johnson, Ganesh Kumar, Bibhudendu Mohapatra, Rajat Mahajan","doi":"10.1055/s-0044-1790515","DOIUrl":"10.1055/s-0044-1790515","url":null,"abstract":"<p><p><b>Objective</b> The objective of this study was to share our early experience with oblique lumbar interbody fusion (OLIF), with emphasis on the perioperative complications and determine clinical outcomes following OLIF. <b>Materials and Methods</b> It was a retrospective prospective study performed at a single institute from March 2019 to August 2023. A total of 56 consecutive patients who had undergone OLIF for degenerative spine disorders were enrolled in the study. Pre-, intra-, and postoperative data on these patients were collected. All the patients were followed up at regular intervals with an evaluation of Visual Analog Scale (VAS), Oswestry Disability Index (ODI), neurological parameters, and X-rays to look for fusion, screw loosening, pseudoarthrosis, and cage slippage. Statistical analysis was done with the odds ratio, chi-square test, and Student's <i>t</i> -test. A <i>p-</i> value of < 0.05 was considered significant. <b>Results</b> The overall incidence of complications was 25%, with no mortality. Intraoperative complications were noted in 10.7% of cases. This included endplate fractures ( <i>n</i> = 3), peritoneal lacerations ( <i>n</i> = 2), and ureteric injury ( <i>n</i> = 1). The most common early postoperative complications were postoperative ileus ( <i>n</i> = 6), followed by anterior thigh or groin numbness ( <i>n</i> = 3), ipsilateral psoas weakness ( <i>n</i> = 2), and superficial surgical site infection ( <i>n</i> = 2). Of the late postoperative complications, cage subsidence was the most common, which occurred in 4 patients, followed by adjacent segment degeneration ( <i>n</i> = 2) and loss of indirect decompression ( <i>n</i> = 1). The mean ODI and VAS scores showed significant improvement ( <i>p</i> < 0.05) at the final follow-up. <b>Conclusion</b> OLIF is a promising surgical technique with the potential to treat a variety of degenerative conditions of the lumbar spine with a good clinical outcome. Despite its various benefits, OLIF can lead to complications in rare instances, which every spine surgeon should be aware of.</p>","PeriodicalId":94300,"journal":{"name":"Asian journal of neurosurgery","volume":"19 4","pages":"721-727"},"PeriodicalIF":0.0,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588599/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142741659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Krushikumar B Soladhra, Arvindkumar Verma, Varshesh K Shah, Dharmikkumar K Velani, Jaimin Modh
{"title":"Superior Cerebellar Artery Aneurysm in a Case of Moyamoya Disease: A Rare Entity.","authors":"Krushikumar B Soladhra, Arvindkumar Verma, Varshesh K Shah, Dharmikkumar K Velani, Jaimin Modh","doi":"10.1055/s-0044-1790518","DOIUrl":"10.1055/s-0044-1790518","url":null,"abstract":"<p><p>Moyamoya disease is a rare condition characterized by progressive narrowing and occlusion of internal carotid artery and other major arteries of the brain with formation of multiple collaterals. The incidence of aneurysm in moyamoya disease is higher than normal population. Treating the simultaneous pathology of aneurysm and moyamoya disease in an individual is a rare entity. A 35-year-old male presented with headache, loss of consciousness, and generalized tonic-clonic seizure with subarachnoid hemorrhage. Digital Subtraction angiography showed moyamoya disease with left superior cerebellar artery aneurysm. Rupture of aneurysm was suspected to be the source of subarachnoid hemorrhage. Patient underwent clipping of the left superior cerebellar artery aneurysm with encephalo-duro-arterio-myo-synangiosis. Patient survived the procedures. All patients with subarachnoid hemorrhage in moyamoya disease should undergo angiogram and aneurysm should be looked for carefully. The site of aneurysm and the risk for damaging the collaterals should be kept in mind while planning the surgery in such cases.</p>","PeriodicalId":94300,"journal":{"name":"Asian journal of neurosurgery","volume":"19 4","pages":"808-811"},"PeriodicalIF":0.0,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588598/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142741950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zuhdy Alsheik, Emil Margolin, Sharif Robin, Daniel Dykman, Haim Ezer
{"title":"Multiple Shunt Catheter Tips Migration into an Inguinal Hernia in an Adult.","authors":"Zuhdy Alsheik, Emil Margolin, Sharif Robin, Daniel Dykman, Haim Ezer","doi":"10.1055/s-0044-1790291","DOIUrl":"10.1055/s-0044-1790291","url":null,"abstract":"<p><p>Although ventriculoperitoneal shunt tip migration into an inguinal hernia is considered common in children, while in adults it is quite rare. In fact, only a handful of cases have been reported in the literature. We report a rare case whereby two catheter tips (one from a lateral ventricle shunt and a second from a 4th ventricular shunt) migrated into an inguinal hernia. This migration caused distal shunt malfunction, and only distal catheter shortening and suturing to the abdominal wall caused the two shunts to function again.</p>","PeriodicalId":94300,"journal":{"name":"Asian journal of neurosurgery","volume":"19 4","pages":"805-807"},"PeriodicalIF":0.0,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588593/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142741100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rajan Pandya, Ponraj Kamatchi Sundaram, Shashank Singh Baghel
{"title":"Comparison of Effectiveness of Brivaracetam and Levetiracetam for Prophylaxis of Early Post-Traumatic Seizures: A Prospective Comparative Interventional Study.","authors":"Rajan Pandya, Ponraj Kamatchi Sundaram, Shashank Singh Baghel","doi":"10.1055/s-0044-1790516","DOIUrl":"10.1055/s-0044-1790516","url":null,"abstract":"<p><p><b>Introduction</b> Early posttraumatic seizures (EPTS) are a major complication after a head injury, defined as seizures developing within the first 7 days of trauma. Levetiracetam has become a popular drug for the prevention of posttraumatic seizures in institutions worldwide. However, it has been reportedly associated with adverse effects like behavioral changes and somnolence. This study aimed to compare the efficacy of a newer drug, brivaracetam, which is reported to have a better pharmacokinetic profile. These findings may be significant in providing a safer yet efficacious alternative to levetiracetam. <b>Objective</b> The aim of this study was to evaluate the efficacy of brivaracetam for prophylaxis of EPTS and to compare it with levetiracetam. <b>Materials and Methods</b> A prospective, single-blind, parallel-group (alternate allocation) controlled trial over 100 patients admitted with traumatic brain injury in the Department of Neurosurgery, Goa Medical College, Panaji, Goa, India. The data was analyzed using IBM SPSS Statistics 29.0. <b>Results</b> Twenty patients developed EPTS in the study group: 8 from the group receiving brivaracetam and 12 from the group receiving levetiracetam. Although the brivaracetam group had a lower incidence of EPTS, the difference was not statistically significant. Eleven patients from the levetiracetam group developed side effects, while six patients from the brivaracetam group had side effects. There was no significant difference in the incidence of side effects. <b>Conclusion</b> Brivaracetam has efficacy equal to that of levetiracetam for prophylaxis of EPTS.</p>","PeriodicalId":94300,"journal":{"name":"Asian journal of neurosurgery","volume":"19 4","pages":"728-734"},"PeriodicalIF":0.0,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588607/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142741953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hrvoje Barić, Sara Komljenović, Katarina Bilić, William Migo, Julius Mautin Vitowanu, Andrej Desnica, Goran Mrak
{"title":"Hematologic Indices and Chronic Subdural Hematoma: A Single-Center Cohort Study.","authors":"Hrvoje Barić, Sara Komljenović, Katarina Bilić, William Migo, Julius Mautin Vitowanu, Andrej Desnica, Goran Mrak","doi":"10.1055/s-0044-1790237","DOIUrl":"10.1055/s-0044-1790237","url":null,"abstract":"<p><p><b>Objective</b> Chronic subdural hematoma (cSDH) is common, predominantly affects the elderly, often recurs after treatment, and can have serious complications, including death. Inflammation plays an important role in cSDH and it has been previously shown that some laboratory indices are useful as prognostic markers. The aim was to research the role of hematologic and inflammatory markers in cSDH. <b>Materials and Methods</b> A single-center archival database review to retrieve data on cSDH cases operated on between 2018 and 2020, including: (1) sociodemography (age, gender), (2) clinics (Glasgow Coma Score [GCS], anticoagulants, chronic conditions), (3) laboratory (leukocyte, neutrophil, platelet, C-reactive protein, hemoglobin, red cell distribution width [RDW], neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio [PLR], systemic immune-inflammatory index [SII]), (4) cSDH (size, location, midline shift), and (5) treatment (craniotomy/craniostomy, drainage). Primary outcome was Glasgow Outcome Score (GOS) at discharge and at 1 year, and secondary outcomes were 1 year mortality, resurgery, and recurrence. Hematological and inflammatory indices were compared across two cSDH thickness groups. <b>Results</b> Seventy-two patients were included, 25 women and 47 men, median age 77 years. Seventeen (23.6%) patients had chronic anticoagulant treatment. The majority had a chronic comorbidity: 19 (26.4%) diabetes, 48 (66.7%) hypertension, and 56 (77.8%) other chronic diseases. Median preoperative GCS was 15. Median cSDH thickness was 22.9 mm, sidedness was equally distributed, and midline shift occurred in 60 (83.3 %) patients, with median midline shift of 8.4 mm. The majority of patients underwent a single craniostomy ( <i>n</i> = 44, 61.1%), and in all patients a subdural drainage was placed. Median GOS at discharge and at 1 year postoperatively was 5. Mortality was 11.1%, and 16.7% of patients were lost to follow-up. Within the 1-year follow-up, 27.8% of patients had disease recurrence, 25% underwent a repeat surgery. In the \"above\" versus \"below\" 15 mm cSDH thickness group there were significant differences in P count (211.5 vs. 279.5 × 10 <sup>9</sup> /L, <i>p</i> = 0.009), RDW (13.3 vs. 12.6, <i>p</i> = 0.031), SII (1782 vs. 2653, <i>p</i> = 0.025), and PLR (26.2 vs. 36.7, <i>p</i> = 0.042). <b>Conclusion</b> Hematological indices bear a diagnostic and prognostic potential in cSDH management.</p>","PeriodicalId":94300,"journal":{"name":"Asian journal of neurosurgery","volume":"19 4","pages":"735-740"},"PeriodicalIF":0.0,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588605/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142741999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Arwa Jader, Barbara Buccilli, Danisha Kumar, Oday Atallah, Luqman Munir, Yasser F Almealawy, Michelle Ennabe, Neil Joshi, Urooj Imdad, Albert Alan, Martin Weinand
{"title":"Building a Stronger Backbone: 3D Printing's Role in Treating Spinal Cord Conditions.","authors":"Arwa Jader, Barbara Buccilli, Danisha Kumar, Oday Atallah, Luqman Munir, Yasser F Almealawy, Michelle Ennabe, Neil Joshi, Urooj Imdad, Albert Alan, Martin Weinand","doi":"10.1055/s-0044-1788916","DOIUrl":"10.1055/s-0044-1788916","url":null,"abstract":"<p><p>Spinal cord injuries (SCIs) pose significant challenges as complete nerve regeneration remains limited. The demand for improved technologies in SCI treatment is evident. One such emerging technology is three-dimensional printing (3DP), which, coupled with advancements in medical imaging and bioengineering, has significantly enhanced precision in surgical procedures. This systematic review aims to explore 3DP as a treatment option for SCIs, examining its cost, efficacy, safety, and the associated technological constraints. A systematic search of Medline was conducted through PubMed for literature published since 2019. The search results were exported to Rayyan for abstract and full-text screening following predefined criteria. The risk of bias in the selected studies was assessed using the RoB2 tool and the Newcastle-Ottawa Scale. From a total of 89 articles screened, 11 studies met the eligibility criteria, collectively assessing 237 individuals with various types of SCIs, including lumbar degeneration, en bloc resection of thoracolumbar metastasis, adult spinal deformity, and cervical degeneration. These studies examined the utilization of 3DP devices such as hand orthosis, interbody fusion cages, lamellar titanium cages, artificial vertebral bodies, and others. Most of the reviewed studies reported positive treatment outcomes, with the actual procedure costs varying from $65 to $5,000. Recent literature shows positive outcomes in the use of 3DP technologies for SCIs, highlighting its potential for enhancing both surgical and nonsurgical interventions. These advancements usher in a new era in SCI treatment, providing enhanced precision and a wider range of treatment options, ultimately leading to more comprehensive and effective patient care.</p>","PeriodicalId":94300,"journal":{"name":"Asian journal of neurosurgery","volume":"19 4","pages":"587-597"},"PeriodicalIF":0.0,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588600/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142741949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kugan Vijian, Bik Liang Lau, Davendran Kanesen, Swee San Lim, Donald L Ngian, Albert S Hieng Wong
{"title":"Improving Diagnostic Yield and Accuracy of Stereotactic Biopsies through Changes in Practice and Techniques: An 8-Year Single-Center Comparative Study.","authors":"Kugan Vijian, Bik Liang Lau, Davendran Kanesen, Swee San Lim, Donald L Ngian, Albert S Hieng Wong","doi":"10.1055/s-0044-1789593","DOIUrl":"10.1055/s-0044-1789593","url":null,"abstract":"<p><p><b>Background</b> Stereotactic biopsies are used to aid neurosurgeons in clinching the diagnosis of intracranial lesions that are difficult to access surgically. A published study of stereotactic biopsies in our center demonstrated a diagnostic yield of only 76% for biopsies from the year 2014 to 2019. A set of criteria/prerequisites was applied to increase yield. <b>Objective</b> The aim of the study was to identify the improvement in accuracy and yield after implementation of a set of criteria/prerequisites. <b>Materials and Methods</b> This was a retrospective and prospective analysis of all patients who underwent stereotactic biopsies from the year 2014 to 2022. This study was conducted at Sarawak General Hospital, Malaysia. A set of stereotactic criteria/prerequisites was introduced since 2020, which include preoperative careful, meticulous trajectory planning and target selection, regular checking and maintenance of equipment, larger burr holes, and good sampling techniques. <b>Results</b> A total of 83 patients underwent stereotactic biopsies from the year 2014 to 2022. Frameless and frame-based methods were used for 45 (54%) and 38 (46%) patients, respectively. The overall diagnostic yield of all biopsies was 84%. Fifty patients underwent stereotactic biopsies prior to implementation of good practice guidelines in 2020 with a positive histopathological yield and accuracy of 76 and 88%, respectively. Thirty-three biopsies done postimplementation demonstrated a yield and accuracy of 97% ( <i>p</i> < 0.05). There was also a shift of preference toward frame-based methods after 2019, with 85% of these biopsies being frame based. <b>Conclusion</b> This comparative study shows that adherence to specific stereotactic biopsy guidelines and techniques introduced in our center has successfully improved our biopsy yield and accuracy.</p>","PeriodicalId":94300,"journal":{"name":"Asian journal of neurosurgery","volume":"19 4","pages":"701-706"},"PeriodicalIF":0.0,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588611/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142741965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Manikandan Sethuraman, Ajay Prasad Hrishi P, Neeraja Ajayan, Unnikrishnan Prathapadas, Smita Vimala, Ranganatha Praveen C S
{"title":"Evaluation of Cardiac Function in Patients with Supratentorial Tumors and Raised Intracranial Pressure: HABIT-ICP, a Prospective Observational Study Using Transthoracic Echocardiography.","authors":"Manikandan Sethuraman, Ajay Prasad Hrishi P, Neeraja Ajayan, Unnikrishnan Prathapadas, Smita Vimala, Ranganatha Praveen C S","doi":"10.1055/s-0044-1789262","DOIUrl":"10.1055/s-0044-1789262","url":null,"abstract":"<p><p><b>Objective</b> An acute increase in intracranial pressure (ICP) has been shown to affect cardiac function due to brain ischemia and the associated increased sympathetic activity. However, there is limited literature on the changes in cardiac function in clinical scenarios where there is a gradual and progressive increase in ICP, such as in brain tumors. We aimed to assess and compare the cardiac function in patients with primary supratentorial brain tumors presenting with and without raised ICP for neurosurgery. <b>Materials and Methods</b> In this prospective observational study, we included 60 patients; Group I (30 patients without features of raised ICP) and Group II (30 patients with features of raised ICP). Transthoracic echocardiography was performed on the day before the surgery and the seventh postoperative day. Hemodynamic, electrocardiographic, and echocardiographic parameters were obtained during pre-, intra-, and postoperative periods and were used for statistical analysis. <b>Results</b> We found an increased relative wall thickness and an increased incidence of systolic (22%) and diastolic dysfunction (33.3%) in Group II compared with Group I patients. There was an increased incidence of intraoperative adverse events such as postinduction hypotension and vasopressor use in Group II patients. In the postoperative period, there was an improvement in the systolic function; however, the chamber dimensions and diastolic dysfunction did not improve significantly. <b>Conclusion</b> Our study suggests that raised ICP might contribute to the pathophysiology of sympathetic overactivity and sympathetically driven cardiac dysfunction, which does not entirely revert in the immediate postoperative period.</p>","PeriodicalId":94300,"journal":{"name":"Asian journal of neurosurgery","volume":"19 4","pages":"693-700"},"PeriodicalIF":0.0,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588615/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142741992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kumar Vaibhav, Anurag Sahu, Ravi Shankar Prasad, Debabrata Deb, Devendra Kumar, Abjad Karimi
{"title":"Prediction of Postoperative Recurrence of Chronic Subdural Hematoma Using Preoperative Systemic Immune Inflammation Index and Eosinophils.","authors":"Kumar Vaibhav, Anurag Sahu, Ravi Shankar Prasad, Debabrata Deb, Devendra Kumar, Abjad Karimi","doi":"10.1055/s-0044-1789247","DOIUrl":"10.1055/s-0044-1789247","url":null,"abstract":"<p><p><b>Objective</b> Chronic subdural hematoma (CSDH) is a common neurological problem with significant recurrence after surgery. Risk considerations can vary, ranging from patient-related factors to those related to the surgical procedure. This study explores the association between preoperative eosinophil count and systemic immune inflammation (SII) with CSDH recurrence. <b>Materials and Methods</b> We conducted a prospective analysis of 105 patients with equal numbers of CSDHs who underwent surgery for CSDH between January 2023 and January 2024. The preoperative eosinophil counts, along with other differential leukocyte counts, were measured. The SII index was calculated using the standard formula (SII = neutrophil count × platelet count/lymphocyte count). Multivariate and univariate regression analyses were performed to assess the association between risk factors and CSDH recurrence. <b>Results</b> The preoperative eosinophil count showed a significant correlation with recurrence ( <i>p</i> < 0.001). The SII index was significantly higher in patients with recurrent CSDH ( <i>p</i> = 0.003). Neutrophils were found to be significantly associated with CSDH recurrence ( <i>p</i> = 0.038). Age ( <i>p</i> < 0.001) and SII ( <i>p</i> = 0.005) were found to be independent predictors of CSDH recurrence, whereas hematoma volume ( <i>p</i> < 0.001) and the antiplatelet regimen were a significant predictor of CSDH recurrence ( <i>p</i> = 0.047). Variables like male gender, diabetes mellitus, anticoagulants, and hematoma volume were associated with eosinophil-rich or eosinophil-poor status. <b>Conclusion</b> Preoperative eosinophil count, neutrophils, and the SII index may serve as potential predictors of CSDH recurrence. Further studies with larger sample sizes are needed to validate these findings.</p>","PeriodicalId":94300,"journal":{"name":"Asian journal of neurosurgery","volume":"19 4","pages":"707-714"},"PeriodicalIF":0.0,"publicationDate":"2024-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588619/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142741639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}