Asian journal of neurosurgery最新文献

{"title":"The Role of Hypertonic Saline in the Management of Acute Traumatic Spinal Cord Injury: A Narrative Review of the Literature.","authors":"Syed Faisal Nadeem, Ahmad Hassan, Tabinda Tahir, Luis E Carelli, Andres M Rubiano, Ahsan Ali Khan","doi":"10.1055/s-0045-1808234","DOIUrl":"10.1055/s-0045-1808234","url":null,"abstract":"<p><p>Traumatic spinal cord injury (TSCI) is a prevalent condition associated with high morbidity and mortality. The pathophysiology of TSCI involves primary injury from the traumatic insult itself and secondary injury (SI) from maladaptive biological processes that serve to aggravate the original insult, such as edema and inflammation, which exacerbate the primary injury and prevent healing and recovery. Research is currently underway to derive therapies to reduce SI-mediated damage. Hypertonic saline (HTS) has emerged as one such therapy. We conducted a literature search for animal and human studies investigating the role of HTS in TSCI on PubMed. Murine studies have shown it to possess antiedema, anti-inflammatory, and vasodilatory properties, which aid in reducing SI and thus improving functional outcomes. Combining HTS with other drugs such as procoagulants, methylprednisolone, and nitroprusside has also been shown to possess greater therapeutic benefit in rodent models of TSCI compared with single therapy with HTS. No human studies have been done till now to assess the benefits of HTS in improving human TSCI outcomes. Future research must focus on determining specific dosing and frequency regimens for HTS in human TSCI patients and on elucidating the extent of benefit it provides to them in improving their outcomes.</p>","PeriodicalId":94300,"journal":{"name":"Asian journal of neurosurgery","volume":"20 3","pages":"456-461"},"PeriodicalIF":0.0,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12370345/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microscopic Resection of Intracranial Lesions with Tubular Retractor of Plastic Syringe: A Single-Center Experience of 157 Cases.","authors":"Mohan Karki, Manish Vaish, Yaspal Singh Bundela, Hrishikesh Chakrabartty, Yam Bahadur Roka, Dipanshu Narula, Rakesh Pandey","doi":"10.1055/s-0045-1809154","DOIUrl":"10.1055/s-0045-1809154","url":null,"abstract":"<p><strong>Objective: </strong>Deeply located intracranial lesions such as intraparenchymal and intraventricular lesions are surgically challenging and associated with unavoidable complications such as seizure, surgical bed hematoma, and brain contusion caused by traction. The objective of this study is to evaluate the safety and effectiveness of the microscopic tubular retractor of a plastic syringe for the resection of deeply located brain lesions.</p><p><strong>Materials and methods: </strong>We retrospectively studied 157 patients with deep-seated intracranial lesions who underwent microscopic resection with the help of a tubular retractor made of a plastic syringe and Teflon introducer between January 2018 and January 2024 in a tertiary hospital. All deep-seated lesions were such as neurocytoma, lymphoma, ependymoma, colloid cysts, metastatic brain tumors, astrocytoma, and meningiomas. We evaluated all patients postoperatively with computed tomography (CT) scan on the first/second day of surgery. The amount of blood loss, the complications, and the mortality rate were recorded.</p><p><strong>Results: </strong>There were 104 males and 53 females with a mean age of 54.13 (range: 15-80) years. Gross total resection was obtained in 85.35% and subtotal in 14.65% of patients. Complications such as surgical bed hematoma in 5.73%, seizure in 3.18%, weakness in 2.54%, and contusion in 3.82% of patients were noted. The blood loss varied from 30 to 500 mL (average, 100 mL). The mortality rate was observed in 2.54% of all patients. Follow-up ranged from 1 to 25 months (average, 10 months).</p><p><strong>Conclusion: </strong>Plastic syringe tubular retractor with Teflon introducer system is safe and effective for the treatment of deeply located intracranial lesions in terms of low morbidity and excellent rate of resection.</p>","PeriodicalId":94300,"journal":{"name":"Asian journal of neurosurgery","volume":"20 3","pages":"572-580"},"PeriodicalIF":0.0,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12370340/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Analysis of Bite Force after Cranioplasty with and without Temporalis Dissection in Large Skull Defects Caused by Decompressive Craniectomy.","authors":"Soumya Deepta Nandi, Raja K Kutty, Jyothish Laila Sivanandapanicker, Sunilkumar Balakrishnan Sreemathyamma, Raj S Chandran, Rosebist Pathrose Kamalabai, Libu Gnanaseelan Kanakamma, Rajmohan Bhanu Prabhakar, Sureshkumar Kunjuni Leela, Anilkumar Peethambaran","doi":"10.1055/s-0045-1809047","DOIUrl":"10.1055/s-0045-1809047","url":null,"abstract":"<p><strong>Introduction: </strong>Cranioplasty involves repairing the skull defect using an autologous bone flap or synthetic molds. The temporalis muscle, detached during decompressive craniectomy (DC), may be reattached to the bone flap for better cosmetic reconstruction. Along with the masseter and pterygoid muscles, the temporalis muscle significantly contributes to the human bite force. In this study, we analyze patients' bite force in which the temporalis muscle was either dissected and reattached or left undisturbed during cranioplasty.</p><p><strong>Materials and methods: </strong>All patients who previously underwent DC for traumatic brain injury or stroke were grouped into two, depending on the method of cranioplasty. In group 1, patients underwent temporalis muscle dissection and reattachment to the bone flap or prosthesis. In group 2, the temporalis muscle was left undisturbed. The bite force of the subjects was measured bilaterally in both groups by a gnathodynamometer before cranioplasty and 3 months after the surgery. We compared the difference in bite force of the subjects individually on both sides, preoperatively and postoperatively, as well as between the groups.</p><p><strong>Results: </strong>This study included 36 patients over 18 years of age, with 18 patients in each group. Preoperatively, the bite force of all the subjects was decreased on the side of the DC compared with the normal side. After cranioplasty, the bite force significantly improved compared with preoperative values in both groups.</p><p><strong>Conclusion: </strong>Temporalis dissection can be safely done during cranioplasty. There is improvement in bite force after cranioplasty with or without temporalis dissection.</p>","PeriodicalId":94300,"journal":{"name":"Asian journal of neurosurgery","volume":"20 3","pages":"542-548"},"PeriodicalIF":0.0,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12370351/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endoscopic Third Ventriculostomy in a Child with Tectal Glioma and Extremely Diminished Prepontine Interval.","authors":"Mohammad Elbaroody, Mahmoud Talaat Shafiey, Wally Hesham Moemen, Ehab El Refaee","doi":"10.1055/s-0045-1809052","DOIUrl":"10.1055/s-0045-1809052","url":null,"abstract":"<p><p>Diminished prepontine interval is a challenging intraoperative finding that creates an additional risk while doing an endoscopic third ventriculostomy (ETV) due to the proximity of the basilar artery to the ventriculostomy site. It is not a contraindication for the procedure especially in patients with thinned floors through which the vascular structures can be easily visualized and it was not proven to be a risk factor for failure of the procedure. Old children with hydrocephalus secondary to tectal glioma have a high chance of successful ETV, thus avoiding shunt dependency. A 12-year-old male patient presented with headache and grade III papilledema, magnetic resonance imaging brain revealed tectal glioma and triventricular hydrocephalus. He underwent a successful ETV despite a challenging intraoperative, extremely diminished prepontine interval. At 1-year follow-up, brain imaging showed a complete resolution of hydrocephalus and stationary course for the tectal glioma. The present case highlights that diminished prepontine interval is not a contraindication for doing ETV unless safety cannot be guaranteed, and it was not proven to be a risk factor for ETV failure. Creating a stoma on the dorsum sellae after palpating the bone or just behind it using blunt fenestration is a safe way especially in the presence of a thinned third ventricle floor with clearly visualized vascular structures.</p>","PeriodicalId":94300,"journal":{"name":"Asian journal of neurosurgery","volume":"20 3","pages":"651-655"},"PeriodicalIF":0.0,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12370332/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Comparative Study on the Trends of Blood Glucose, Serum Triglycerides, and CRP-Based Levels in Correlation with GCS among Patients with Traumatic Head Injury.","authors":"Santhosh Kumar Elango, Saravanan M P, Harini Jayaraman, Santhosh Viswan, Ebrahim Fathima Hajira E A","doi":"10.1055/s-0045-1808246","DOIUrl":"10.1055/s-0045-1808246","url":null,"abstract":"<p><strong>Background: </strong>Traumatic head injury, which has a high mortality rate, can present as mild contusions, hemorrhages (subdural, extradural, intraparenchymal), diffuse axonal injuries, or direct penetrating injuries. Glasgow Coma Scale (GCS) is used to assess the severity of head injury. Stress-induced hyperglycemia associated with traumatic brain injury has high mortality compared with hyperglycemia in diabetic patients. Stress-induced hyperglycemia not only occurs due to head injury but also serves as a predictor of its outcome. C-reactive protein (CRP) levels are also associated with severity of head injury. Triglyceride levels are said to correlate with neuroinflammation and apoptosis, thus pivotal with severity of traumatic brain injury. With this background, this study aims to compare the levels of blood glucose, CRP, and serum triglycerides in patients with traumatic head injury according to their level of consciousness.</p><p><strong>Objectives: </strong>This article compares the levels of blood glucose, CRP, and serum triglyceride in traumatic head injury patients according to their GCS and assesses their trends.</p><p><strong>Materials and methods: </strong>Patients were divided into two groups (patients with GCS ≤ 8 as group 1 and patients with GCS > 8 as group 2). Blood was collected in these patients at admission, 24 hours after admission, and 48 hours after admission. Glucose was estimated at admission, 24 hours, and 48 hours after admission. CRP and triglycerides were estimated after 24 and 48 hours after admission. The levels were compared between groups and also their trends were assessed.</p><p><strong>Statistics: </strong>Mean and standard deviation were calculated for the above parameters using Excel. Statistical analysis was done using SPSS software version 26. Statistical significance was assessed using \" <i>t</i> -test\" and \"analysis of variance.\" A <i>p</i> -value of < 0.05 was considered statistically significant.</p><p><strong>Results: </strong>Group 1 showed increased levels of glucose after 24 and 48 hours compared with group 2. CRP showed increased levels in group 1 compared with group 2. There was no significant difference in triglyceride levels between the two groups. Levels of blood glucose showed decreasing trends in group 2. CRP showed increasing trend in group 1. Triglyceride levels showed increasing trend in both the groups.</p><p><strong>Conclusion: </strong>The decreasing trend in glucose levels in group 2 and increasing trend in CRP levels in group 1 are due to the same pathogenesis, which is associated with the severity of head injury. Increased trends in triglyceride levels were seen in both the groups. Since the association of levels of these parameters and their trends with severity of head injury, regular and serial monitoring of these analytes may be used as prognostic marker.</p>","PeriodicalId":94300,"journal":{"name":"Asian journal of neurosurgery","volume":"20 3","pages":"523-528"},"PeriodicalIF":0.0,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12370341/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current Insights and Management Strategies for Lower Cervical Arteriovenous Fistulas: A Comprehensive Review.","authors":"Prasert Iampreechakul, Korrapakc Wangtanaphat, Songpol Chuntaroj, Chonlada Angsusing, Yodkhwan Wattanasen, Sunisa Hangsapruek, Punjama Lertbutsayanukul, Somkiet Siriwimonmas","doi":"10.1055/s-0045-1809046","DOIUrl":"10.1055/s-0045-1809046","url":null,"abstract":"<p><p>Lower cervical arteriovenous fistulas (AVFs) are rare and complex vascular malformations that pose significant clinical challenges due to their location and variable presentation. While upper cervical AVFs have been extensively studied, lower cervical AVFs remain underresearched. This study aims to review the clinical presentations, management strategies, and outcomes of patients with lower cervical AVFs to enhance understanding and improve treatment approaches. We conducted a retrospective analysis of patients with spinal vascular malformations treated at our institute between June 2006 and December 2023, identifying two cases of lower cervical AVFs. Additionally, a systematic literature review was performed following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, including 44 patients with lower cervical AVFs, using databases such as Ovid MEDLINE, PubMed, and Cochrane. Data collected included patient demographics, clinical presentation, fistula type, arterial and venous involvement, treatment modality, and neurological outcomes. Among the 44 patients with lower cervical AVFs, including our two cases, 50% were female, and the mean age was 48.68 years (range: 4-76 years). Clinical presentations varied, with 27.3% experiencing hemorrhage, 18.2% presenting with myelopathy, and 18.2% remaining asymptomatic. Venous drainage patterns played a significant role in symptom severity, with complex perimedullary and retrograde venous drainage contributing to worse outcomes. Treatment included endovascular embolization (40.9%), surgical resection (25%), and combined approaches (18.2%), with good recovery achieved in 54.5% of cases. Lower cervical AVFs present diverse clinical challenges due to their variable presentations and complex vascular anatomy. Early diagnosis and tailored management, including endovascular embolization and surgical resection, are essential for optimizing patient outcomes. Further research is needed to better understand the natural history of asymptomatic AVFs and improve treatment protocols.</p>","PeriodicalId":94300,"journal":{"name":"Asian journal of neurosurgery","volume":"20 3","pages":"462-477"},"PeriodicalIF":0.0,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12370346/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detection and Predictors of Arrhythmia in Patients with Chronic Noncardioembolic Ischemic Stroke on Wearable Electrocardiogram Device.","authors":"Yu Akimoto, Yoshiro Ito, Hideo Tsurushima, Hisayuki Hosoo, Aiki Marushima, Mikito Hayakawa, Kazuhiro Nakamura, Keishi Fujita, Toshitsugu Terakado, Hiroshi Yamagami, Yuji Matsumaru, Eiichi Ishikawa","doi":"10.1055/s-0045-1809050","DOIUrl":"10.1055/s-0045-1809050","url":null,"abstract":"<p><strong>Objectives: </strong>The screening examination for arrhythmias in patients with chronic noncardioembolic ischemic stroke is limited. This study aimed to investigate the prevalence of arrhythmia in patients with chronic noncardioembolic ischemic stroke using a stick-on wearable device.</p><p><strong>Materials and methods: </strong>This was a prospective observational study conducted between July 2020 and February 2022 involving 176 patients with a history of noncardioembolic ischemic stroke. Patients receiving anticoagulant therapy were excluded. For the evaluation of arrhythmias, the patients wore a stick-on wearable device for a maximum of approximately 7 days. We investigated the prevalence of arrhythmia and its associated factors.</p><p><strong>Results: </strong>The mean measurement time was 121.3 ± 45.3 hours. Atrial fibrillation was present in 2 (1.1%) patients, frequent premature atrial contractions (PACs) in 69 (39.2%), and frequent premature ventricular contractions (PVCs) in 36 (20.5%). Regression analysis showed that the risk factors independently associated with frequent PACs were age (odds ratio [OR] 1.103, 95% confidence interval [CI] 1.055-1.153; <i>p</i>  < 0.001) and cilostazol use (OR 2.681, 95% CI 1.338-5.371; <i>p</i>  = 0.005). Regression analysis showed that the risk factors independently associated with frequent PVCs were age (OR 1.047, 95% CI 1.002-1.095; <i>p</i>  = 0.043), male sex (OR 3.834, 95% CI 1.441-11.045; <i>p</i>  = 0.013), and cilostazol use (OR 2.968, 95% CI 1.363-6.463; <i>p</i>  = 0.006).</p><p><strong>Conclusion: </strong>The prevalence of frequent PVCs is higher in patients with chronic noncardioembolic ischemic stroke than in the general population. The stick-on wearable device is a useful screening tool for arrhythmia in patients with chronic noncardioembolic ischemic stroke.</p>","PeriodicalId":94300,"journal":{"name":"Asian journal of neurosurgery","volume":"20 3","pages":"549-555"},"PeriodicalIF":0.0,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12370338/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intraventricular Trigone Pleomorphic Xanthoastrocytoma: A Rare Presentation with Favorable Prognosis in a Young Adult-A Case Report.","authors":"Chonnawee Chaisawasthomrong","doi":"10.1055/s-0045-1809031","DOIUrl":"10.1055/s-0045-1809031","url":null,"abstract":"<p><p>Pleomorphic xanthoastrocytoma (PXA) is a rare, Grade II astrocytic tumor typically found in the temporal lobe and often presents with seizures. We report a unique case of intraventricular trigone PXA, a rare location that mimicked an intraventricular meningioma on imaging. A 26-year-old male presented with progressive visual loss, and magnetic resonance imaging revealed a well-defined lesion in the right lateral ventricle. The patient underwent subtotal tumor resection, followed by adjuvant radiotherapy. Histopathological analysis confirmed PXA with BRAF V600E mutation, and subsequent imaging showed successful tumor control with no recurrence after 2 years. This case highlights the importance of differentiating PXA from other neoplasms, such as meningiomas, and demonstrates the favorable prognosis of PXA when appropriately managed.</p>","PeriodicalId":94300,"journal":{"name":"Asian journal of neurosurgery","volume":"20 3","pages":"646-650"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12370325/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management Protocols for Sepsis and Septic Shock after Craniotomy: Clinical Outcomes and Survival Analysis.","authors":"Panu Boontoterm, Siraruj Sakoolnamarka, Karanarak Urasyanandana, Pusit Fuengfoo","doi":"10.1055/s-0045-1809051","DOIUrl":"10.1055/s-0045-1809051","url":null,"abstract":"<p><strong>Objectives: </strong>Central nervous system infections are linked to a substantial rise in perioperative mortality, with postoperative neurosurgical infections being both prevalent and severe. Although the Surviving Sepsis Campaign (SSC) guidelines offer a framework for managing sepsis, their effect on clinical outcomes in neurosurgical patients has yet to be fully explored. The aim of this study was to compare mortality rates and clinical outcomes in neurosurgical patients with sepsis and septic shock treated according to the SSC protocol versus standard care.</p><p><strong>Materials and methods: </strong>This single-center retrospective analysis on prospectively acquired data included 159 patients with neurosurgical sepsis and septic shock, divided into two groups: 77 patients managed according to the SSC guidelines and 82 patients receiving standard treatment. Data on baseline characteristics, initial management within the first hour, and 30-day clinical outcomes were collected and analyzed.</p><p><strong>Results: </strong>The mortality rate was significantly lower in the SSC protocol group. Additionally, intensive care unit (ICU) length of stay was significantly shorter, and the number of ventilator- and vasopressor-free days was significantly higher in the SSC protocol group ( <i>p</i>  < 0.001). Hydrocortisone use was associated with reduced vasopressor requirements and shorter hospital stays ( <i>p</i>  = 0.001 and <i>p</i>  < 0.001, respectively). Thiamine use was linked to a shorter hospital stay ( <i>p</i>  = 0.023), while continuous renal replacement therapy significantly reduced vasopressor use ( <i>p</i>  = 0.013).</p><p><strong>Conclusion: </strong>Implementing the SSC protocol within the first hour of treatment significantly reduced mortality, shortened ICU length of stay, and increased the number of ventilator- and vasopressor-free days.</p>","PeriodicalId":94300,"journal":{"name":"Asian journal of neurosurgery","volume":"20 3","pages":"564-571"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12370350/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postpartum Pseudoadenomatous Hypophysitis Simulating a Pituitary Macroadenoma: A Case Report and Literature Review.","authors":"Elkorno Mohammed, Oudrhiri Mohammed Yassaad, Elkorno Hajar, Elouahabi Abdessamad, Cherradi Nadia, Elouazzani Hafssa, Arkha Yasser","doi":"10.1055/s-0045-1808057","DOIUrl":"10.1055/s-0045-1808057","url":null,"abstract":"<p><p>Inflammatory hypothalamo-hypophyseal disorders are uncommon, representing only 1% of hypophyseal lesions. Among these, postpartum lymphocytic hypophysitis emerges as a particularly notable etiology. As a relatively recent entity, its recognition mandates a multidisciplinary approach to ensure preservation of compromised vital prognosis and amelioration of associated neuro-ophthalmologic and/or hypophyseal manifestations. We present a remarkable case of lymphocytic hypophysitis in a 32-year-old woman, unveiled during the postpartum period. Despite employing magnetic resonance imaging (MRI), preoperative diagnosis remained challenging. Surgical intervention became imperative due to progressive visual impairments. Postoperative course demonstrated favorable evolution, characterized by significant enhancement in visual acuity and normalization of cerebral MRI findings during follow-up.</p>","PeriodicalId":94300,"journal":{"name":"Asian journal of neurosurgery","volume":"20 3","pages":"621-626"},"PeriodicalIF":0.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12370331/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}