Annals of dermatology最新文献_第8页

Molluscum Contagiosum Mimicking Verruca Vulgaris on the Sole. 在鞋底上模仿普通疣的传染性软体动物。

Annals of dermatology Pub Date : 2023-05-01 DOI: 10.5021/ad.21a.064

Seung Hui Seok, Moon Soo Yoon, Jung U Shin

引用次数: 0

New Onset of Alcohol Flushing in an Atopic Dermatitis Patient Treated with Dupilumab. Dupilumab治疗的特应性皮炎患者出现新的酒精性潮红。

Annals of dermatology Pub Date : 2023-05-01 DOI: 10.5021/ad.21b.038

Hoon Choi, Dong Hyun Shim, Min Sung Kim, Bong Seok Shin, Chan Ho Na

{"title":"New Onset of Alcohol Flushing in an Atopic Dermatitis Patient Treated with Dupilumab.","authors":"Hoon Choi, Dong Hyun Shim, Min Sung Kim, Bong Seok Shin, Chan Ho Na","doi":"10.5021/ad.21b.038","DOIUrl":"10.5021/ad.21b.038","url":null,"abstract":": Dupilumab is a monoclonal antibody that targets the alpha subunit of the interleukin-4 receptor. It has been used as an effective treatment for moderate to severe atopic dermatitis (AD) patients 1 . The adverse events include conjunctivitis, herpes simplex virus infection, and injection site reaction in varying proportions 1 . A 20-year-old male patient visited our hospital with pruritic erythematous plaques on the entire body from childhood. Based on the clinical findings, AD was diagnosed, and treatment with cyclosporine 100~200 mg was prescribed for more than one year. Because the cyclosporine treatment had not been effective, dupilumab administration was initiated. Subsequently, the patient’s clinical symptoms improved rapidly; however, after several months, he complained of facial flushing within a few minutes of consuming small amounts of alcohol (Fig. 1). He complained that this symptom lasted for less than one hour and had never occurred before treatment with dupilumab. No medications or topical agents were being taken concurrently. We considered the flushing in this patient as a rare adverse event that could occur after treatment with dupilumab, and the patient was educated to avoid alcohol consumption during the post-treatment period. Flushing is a transient erythema that most commonly occurs in the face because of an increase in cutaneous blood flow following vasodilation. One of the causes is the use of vasoactive substances, which include medication, food, and alcohol 2 . Alcohol flushing is caused by an increase in the acetaldehyde level due to deficiency or inactivity of aldehyde dehydrogenase 2 (ALDH2), which plays a major role in alcohol metabolism","PeriodicalId":94298,"journal":{"name":"Annals of dermatology","volume":"35 Suppl 1","pages":"S163-S164"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/01/ba/ad-35-S163.PMC10608370.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49687069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pleomorphic Adenoma Arising from Post-Auricular Heterotopic Salivary Gland Tissue. 耳后异位唾液腺组织引起的多形性腺瘤。

Annals of dermatology Pub Date : 2023-05-01 DOI: 10.5021/ad.20.273

Yeona Kim, Dae-Lyong Ha, Jin-Hwa Son, Jungsoo Lee, Hoon-Soo Kim, Hyun-Chang Ko, Byungsoo Kim, Moon-Bum Kim, Kihyuk Shin

引用次数: 0

Two Cases of Linear Lichen Planus Pigmentosus of the Chin in Korean Women Treated by Fractional Lasers and Polydeoxyribonucleotide Injection. 部分激光联合多核苷酸注射液治疗韩国女性下巴线状色素性扁平苔藓2例。

Annals of dermatology Pub Date : 2023-05-01 DOI: 10.5021/ad.21a.038

Chang Jin Jung, Woo Jin Lee, Chong Hyun Won, Mi Woo Lee, Sung Eun Chang

引用次数: 0

A Case of Pirfenidone-Induced Photosensitive Drug Eruption. 吡非尼酮致光敏性药物疹1例。

Annals of dermatology Pub Date : 2023-05-01 DOI: 10.5021/ad.21.052

Soo Hyun Jeong, Eun Hye Hong, Eun Joo Park, Kwang Joong Kim, Kwang Ho Kim

{"title":"A Case of Pirfenidone-Induced Photosensitive Drug Eruption.","authors":"Soo Hyun Jeong, Eun Hye Hong, Eun Joo Park, Kwang Joong Kim, Kwang Ho Kim","doi":"10.5021/ad.21.052","DOIUrl":"10.5021/ad.21.052","url":null,"abstract":"A 75-year-old male was diagnosed with idiopathic pulmonary fibrosis and treated with pirfenidone. He presented with an erythematous thick scaly patch on his face, neck, and both hands and arms. He had a history of significant exposure to sunlight without using sunscreen. All lesions were restricted to sun-exposed areas and appeared one month ago. Histopathological examination revealed necrotic keratinocytes, epidermal spongiosis, liquefaction degeneration of the basal layer, interface dermatitis, solar elastosis, and upper dermal perivascular lympho-histiocytic infiltration. Based on clinical and histopathological findings, the skin lesion could be diagnosed as photosensitive drug eruption induced by pirfenidone. Pirfenidone was discontinued for a month, and the patient was treated with oral and topical corticosteroids. Consequently, the skin lesion almost fully cleared, leaving mild postinflammatory hyperpigmentation. Although there are many reports of photosensitivity reactions to pirfenidone, dermatologists are still not familiar with this drug. Through this case presentation, clinicians should be aware of the potential phototoxic effects of pirfenidone and provide the necessary precautionary information to patients who take pirfenidone.","PeriodicalId":94298,"journal":{"name":"Annals of dermatology","volume":"35 Suppl 1","pages":"S48-S51"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/18/f9/ad-35-S48.PMC10608387.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49686950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Case of Solitary Fibrous Tumor on the Foot. 足部孤立性纤维瘤1例。

Annals of dermatology Pub Date : 2023-05-01 DOI: 10.5021/ad.21b.028

Ki Hun Lee, Seung Yeon Lee, Bora Lim, Kun Park

引用次数: 0

A Case of Superficial Angiomyxoma Localized on the Nipple in a 12-Year-Old Korean Female. 一例12岁韩国女性乳头局部浅表性血管粘液瘤。

Annals of dermatology Pub Date : 2023-05-01 DOI: 10.5021/ad.21.001

Hyung Keon Park, Sook Jung Yun, Seung-Chul Lee, Jee-Bum Lee

引用次数: 0

Comments on "Eccrine Porocarcinoma: A Multicenter Retrospective Study with Review of the Literatures Reported in Korea". 对“Eccrine Poroccarcinoma:一项多中心回顾性研究和韩国文献综述”的评论。

Annals of dermatology Pub Date : 2023-05-01 DOI: 10.5021/ad.20.178

Young Jae Kim, Hee Joo Yang, Chong Hyun Won

引用次数: 0

Intradermal Low-Fat Spindle Cell Lipoma: A Case Report. 皮内低脂肪梭形细胞脂肪瘤：一例报告。

Annals of dermatology Pub Date : 2023-05-01 DOI: 10.5021/ad.21.051

Hyeong Mok Kwon, Jung Eun Yim, Hye Ri Kim, Dong Hoon Shin, Jong Soo Choi, Young Kyung Bae, Joon Hyuk Choi

{"title":"Intradermal Low-Fat Spindle Cell Lipoma: A Case Report.","authors":"Hyeong Mok Kwon, Jung Eun Yim, Hye Ri Kim, Dong Hoon Shin, Jong Soo Choi, Young Kyung Bae, Joon Hyuk Choi","doi":"10.5021/ad.21.051","DOIUrl":"10.5021/ad.21.051","url":null,"abstract":"Spindle cell lipoma is a rare benign neoplasm that features a mixture of evenly aligned spindle cells, mature adipocytes, and ropey collagen. Most cases of spindle cell lipoma are found in the subcutaneous tissue, and intradermal spindle cell lipoma is rarely reported. We present a case of intradermal spindle cell lipoma in a 46-year-old female who presented with a 0.7-cm flesh-colored and dome-shaped nodule on the right temple that had developed 6 years ago. This mass was excised, and upon histopathologic examination, an unencapsulated lesion was located in the dermis, which consisted of bland spindle cells, scanty mature adipocytes, rare lipoblasts, and ropey collagen bundles with prominent basophilic myxoid stroma. Immunohistochemical staining showed diffuse positivity for CD34, negativity for the S-100 protein, and loss of retinoblastoma protein expression. Based on these features, intradermal low-fat spindle cell lipoma was diagnosed. No evidence of local recurrence was observed 4 months after excision. Intradermal low-fat spindle cell lipomas are extremely rare and can easily be mistaken for tumors that have similar clinical and histopathological findings. Herein, we report a globally rare case of an intradermal low-fat spindle cell lipoma.","PeriodicalId":94298,"journal":{"name":"Annals of dermatology","volume":"35 Suppl 1","pages":"S10-S13"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0b/86/ad-35-S10.PMC10608367.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49687066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Early-Onset Generalized Pustular Psoriasis of Pregnancy Following Hydroxychloroquine Use. 使用羟氯喹后妊娠早期发病的全身性脓疱性银屑病。

Annals of dermatology Pub Date : 2023-05-01 DOI: 10.5021/ad.21.062

Young-Wook Ryoo, Ji-Min Yun, Hyun-Wook Kim, Sung-Ae Kim

{"title":"Early-Onset Generalized Pustular Psoriasis of Pregnancy Following Hydroxychloroquine Use.","authors":"Young-Wook Ryoo, Ji-Min Yun, Hyun-Wook Kim, Sung-Ae Kim","doi":"10.5021/ad.21.062","DOIUrl":"10.5021/ad.21.062","url":null,"abstract":"Generalized pustular psoriasis of pregnancy (GPPP), characterized by widespread sterile pustules and erythematous patches with systemic symptoms such as fever, is a rare form of pustular psoriasis. GPPP typically occurs in the third trimester of pregnancy and can be triggered by various factors such as infections, hypocalcemia, and drugs including N-butyl-scopolammonium bromide. We report a rare case of new-onset GPPP in a 33-year-old multigravida female at 17 weeks' gestation, which occurred earlier than usual, after taking hydroxychloroquine for 3 weeks to treat systemic lupus erythematosus. She stopped her medications and was treated with systemic corticosteroid, but without improvement. Her medication was changed to systemic cyclosporine; her skin lesions improved, which completely resolved after delivery. This is the first case of GPPP developed following hydroxychloroquine use for systemic lupus erythematosus, which occurred earlier than usual and completely resolved after delivery. This case demonstrates that hydroxychloroquine can induce GPPP before the third trimester of pregnancy.","PeriodicalId":94298,"journal":{"name":"Annals of dermatology","volume":"35 Suppl 1","pages":"S43-S47"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/59/27/ad-35-S43.PMC10608382.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49687059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0