{"title":"Association between Family History and Male Androgenetic Alopecia with Female Pattern Hair Loss.","authors":"Sang-Hoon Lee, Hyun Kang, Won-Soo Lee","doi":"10.5021/ad.22.221","DOIUrl":"10.5021/ad.22.221","url":null,"abstract":"<p><strong>Background: </strong>Male androgenetic alopecia (MAGA) is often accompanied by female pattern hair loss (FPHL). However, the risk factors related to MAGA with FPHL are unclear.</p><p><strong>Objective: </strong>To investigate demographic and laboratory factors related to MAGA with FPHL.</p><p><strong>Methods: </strong>This retrospective case-control study was performed in a single tertiary care center for MAGA with FPHL between March 2012 and September 2021. Eligible patients were males >12 years old diagnosed with androgenetic alopecia by a dermatologist. The patients were subdivided into MAGA with FPHL and MAGA without FPHL groups. Comorbidities as well as demographic, laboratory, and disease-specific variables were compared between the two groups. Data analysis was conducted between October 2021 and February 2022. The independent samples t-test, Mann-Whitney U test, and chi-squared test were used to assess the factors that contributed to MAGA with FPHL.</p><p><strong>Results: </strong>Of 469 patients with MAGA, 309 (65.9%) had FPHL, which was a much higher rate than previously reported. Among the variables, only matrilineal (odds ratio, 1.605; 95% confidence interval, 1.014~2.541) and maternal history (odds ratio, 4.705; confidence interval, 1.632~13.559) of androgenetic alopecia were significantly associated with MAGA with FPHL. In the MAGA with FPHL group, a significant positive correlation was noted between body mass index and the type F score (r=0.114, <i>p</i>=0.025).</p><p><strong>Conclusion: </strong>In this case-control study, patients with MAGA and a maternal history of androgenetic alopecia were at risk of FPHL. Therefore, early screening may benefit these patients.</p>","PeriodicalId":94298,"journal":{"name":"Annals of dermatology","volume":"35 5","pages":"348-354"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/50/e6/ad-35-348.PMC10579574.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41224655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mi Hee Kwack, Chang Hyun Song, Seongjin Lee, Gi Ung Ha, Gun-Ho Kim, Weon Ju Lee
{"title":"Effect of a Temperature-Adjustable Cryotherapy Device on Mice with Lysophosphatidic Acid-Induced Pruritus.","authors":"Mi Hee Kwack, Chang Hyun Song, Seongjin Lee, Gi Ung Ha, Gun-Ho Kim, Weon Ju Lee","doi":"10.5021/ad.21.195","DOIUrl":"10.5021/ad.21.195","url":null,"abstract":"","PeriodicalId":94298,"journal":{"name":"Annals of dermatology","volume":"35 5","pages":"381-385"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/80/36/ad-35-381.PMC10579573.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41224657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Case of Primary Cutaneous Perivascular Epithelioid Cell Tumor.","authors":"Haneul Oh, Byeong Geun Park, Il-Hwan Kim","doi":"10.5021/ad.20.322","DOIUrl":"10.5021/ad.20.322","url":null,"abstract":"A primary cutaneous perivascular epithelioid cell tumor (pcPEComa) is an extremely rare mesenchymal tumor composed of perivascular epithelioid cells, a distinctive neoplastic cell with no known normal counterpart 1 . They usually show both melanocytic and smooth muscle differentiation 2 . A","PeriodicalId":94298,"journal":{"name":"Annals of dermatology","volume":"35 Suppl 1","pages":"S155-S157"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2d/d1/ad-35-S155.PMC10608356.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49686951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Seborrheic Dermatitis: A Case of an Atypical Side Effect of Atypical Antipsychotics.","authors":"Ramy Bishay, Janis Chang, Chih-Peng Chang","doi":"10.5021/ad.20.270","DOIUrl":"10.5021/ad.20.270","url":null,"abstract":"","PeriodicalId":94298,"journal":{"name":"Annals of dermatology","volume":"35 Suppl 1","pages":"S184-S185"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/cc/35/ad-35-S184.PMC10608406.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49687076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jee-Woo Kim, Jung Min Ko, Dong Yoon Lee, Jung-Won Shin
{"title":"A Case Report of Rubinstein-Taybi Syndrome Presenting with Extensive Keloid Formation and Review of Literature.","authors":"Jee-Woo Kim, Jung Min Ko, Dong Yoon Lee, Jung-Won Shin","doi":"10.5021/ad.20.320","DOIUrl":"10.5021/ad.20.320","url":null,"abstract":"<p><p>Rubinstein-Taybi syndrome (RSTS) is an extremely rare genetic disorder affecting multi-organ systems. A tendency to form keloid is one of the common dermatologic manifestations. We describe a 23-year-old female presented with extensive keloids which developed spontaneously. She had typical facial features, broad thumbs, and dental defects, which were suspicious features of genetic syndrome. Direct sequencing for cyclic-AMP-regulated enhancer binding protein revealed a novel mutation. So far, 23 cases of RSTS have been reported in Korean literature. To the best of our knowledge, this is the first report in Korea to describe confirmed case of RSTS with extensive keloids as a chief manifestation.</p>","PeriodicalId":94298,"journal":{"name":"Annals of dermatology","volume":"35 Suppl 1","pages":"S19-S24"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0d/ed/ad-35-S19.PMC10608378.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49686955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ruoqu Wei, Haifei Liu, Zhen Zhang, Fuying Chen, Jiawen Chen, Qianyue Xu, Hong Yu, Jianying Liang, Zhirong Yao
{"title":"Coexistence of Subcutaneous Panniculitis-Like T-Cell Lymphoma and Dermatomyositis in a 12-Year-Old Boy.","authors":"Ruoqu Wei, Haifei Liu, Zhen Zhang, Fuying Chen, Jiawen Chen, Qianyue Xu, Hong Yu, Jianying Liang, Zhirong Yao","doi":"10.5021/ad.20.310","DOIUrl":"10.5021/ad.20.310","url":null,"abstract":"<p><p>Subcutaneous panniculitis-like T-cell lymphoma (SPTL) is an extremely rare, indolent skin malignancy that can be difficult to distinguish from autoimmune disease-associated panniculitides. Here, we describe a 12-year-old boy who was diagnosed at age 7 years with dermatomyositis with classical manifestations, including poikiloderma, Gottron's sign, and symmetric muscle weakness. Recently, the boy presented multiple subcutaneous nodules and fever. Histopathological examination and immunohistochemical staining revealed coexistence of SPTL. To our knowledge, this is the first case of dermatomyositis accompanied with SPTL. This case alert clinical physicians of the possibility of SPTL should be considered when a patient with dermatomyositis has new lesions presenting as nodules and unknown fever.</p>","PeriodicalId":94298,"journal":{"name":"Annals of dermatology","volume":"35 Suppl 1","pages":"S79-S83"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/63/b2/ad-35-S79.PMC10608403.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49687052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Molluscum Contagiosum Mimicking Verruca Vulgaris on the Sole.","authors":"Seung Hui Seok, Moon Soo Yoon, Jung U Shin","doi":"10.5021/ad.21a.064","DOIUrl":"10.5021/ad.21a.064","url":null,"abstract":"","PeriodicalId":94298,"journal":{"name":"Annals of dermatology","volume":"35 Suppl 1","pages":"S144-S145"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/79/0d/ad-35-S144.PMC10608405.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49687068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hoon Choi, Dong Hyun Shim, Min Sung Kim, Bong Seok Shin, Chan Ho Na
{"title":"New Onset of Alcohol Flushing in an Atopic Dermatitis Patient Treated with Dupilumab.","authors":"Hoon Choi, Dong Hyun Shim, Min Sung Kim, Bong Seok Shin, Chan Ho Na","doi":"10.5021/ad.21b.038","DOIUrl":"10.5021/ad.21b.038","url":null,"abstract":": Dupilumab is a monoclonal antibody that targets the alpha subunit of the interleukin-4 receptor. It has been used as an effective treatment for moderate to severe atopic dermatitis (AD) patients 1 . The adverse events include conjunctivitis, herpes simplex virus infection, and injection site reaction in varying proportions 1 . A 20-year-old male patient visited our hospital with pruritic erythematous plaques on the entire body from childhood. Based on the clinical findings, AD was diagnosed, and treatment with cyclosporine 100~200 mg was prescribed for more than one year. Because the cyclosporine treatment had not been effective, dupilumab administration was initiated. Subsequently, the patient’s clinical symptoms improved rapidly; however, after several months, he complained of facial flushing within a few minutes of consuming small amounts of alcohol (Fig. 1). He complained that this symptom lasted for less than one hour and had never occurred before treatment with dupilumab. No medications or topical agents were being taken concurrently. We considered the flushing in this patient as a rare adverse event that could occur after treatment with dupilumab, and the patient was educated to avoid alcohol consumption during the post-treatment period. Flushing is a transient erythema that most commonly occurs in the face because of an increase in cutaneous blood flow following vasodilation. One of the causes is the use of vasoactive substances, which include medication, food, and alcohol 2 . Alcohol flushing is caused by an increase in the acetaldehyde level due to deficiency or inactivity of aldehyde dehydrogenase 2 (ALDH2), which plays a major role in alcohol metabolism","PeriodicalId":94298,"journal":{"name":"Annals of dermatology","volume":"35 Suppl 1","pages":"S163-S164"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/01/ba/ad-35-S163.PMC10608370.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49687069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}