Hyung Keon Park, Sook Jung Yun, Seung-Chul Lee, Jee-Bum Lee
{"title":"A Case of Superficial Angiomyxoma Localized on the Nipple in a 12-Year-Old Korean Female.","authors":"Hyung Keon Park, Sook Jung Yun, Seung-Chul Lee, Jee-Bum Lee","doi":"10.5021/ad.21.001","DOIUrl":"10.5021/ad.21.001","url":null,"abstract":": A 12-year-old Korean female presented with a 1-month of tender group of reddish 1 to 3 mm sized dome-shaped papules on the left nipple (Fig. 1). She had no similar lesion on the other site and no family history of similar skin lesions. She had neither pigmented lesions in her skin or mucous membranes, nor any other known medical conditions. The lesion was totally excised and histopathologic examination showed well-circumscribed, non-encapsulated myxoid tumor (Fig. 2A), and stromal mucin was positive for Alcian blue staining (Fig. 2B). Tumor consisted of spindle and stellate cells as well as numerous thin-walled small vessels in the myxoid stroma (Fig. 2C). Immunohistological staining revealed tumor cells were positive for vimentin (Fig. 2D), and positive for α -smooth muscle actin ( α -SMA) (Fig. 2E). Endothelial cells of blood vessels were CD34 positive, but tumor cells were negative (Fig. 2F). The patient was diagnosed with superficial angiomyxoma (SAM) and there was no sign of recurrence after 12 months of follow-up. SAM is an","PeriodicalId":94298,"journal":{"name":"Annals of dermatology","volume":"35 Suppl 1","pages":"S150-S152"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/8f/db/ad-35-S150.PMC10608393.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49686953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comments on \"Eccrine Porocarcinoma: A Multicenter Retrospective Study with Review of the Literatures Reported in Korea\".","authors":"Young Jae Kim, Hee Joo Yang, Chong Hyun Won","doi":"10.5021/ad.20.178","DOIUrl":"10.5021/ad.20.178","url":null,"abstract":"","PeriodicalId":94298,"journal":{"name":"Annals of dermatology","volume":"35 Suppl 1","pages":"S1-S3"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/69/38/ad-35-S1.PMC10608384.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49687053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hyeong Mok Kwon, Jung Eun Yim, Hye Ri Kim, Dong Hoon Shin, Jong Soo Choi, Young Kyung Bae, Joon Hyuk Choi
{"title":"Intradermal Low-Fat Spindle Cell Lipoma: A Case Report.","authors":"Hyeong Mok Kwon, Jung Eun Yim, Hye Ri Kim, Dong Hoon Shin, Jong Soo Choi, Young Kyung Bae, Joon Hyuk Choi","doi":"10.5021/ad.21.051","DOIUrl":"10.5021/ad.21.051","url":null,"abstract":"<p><p>Spindle cell lipoma is a rare benign neoplasm that features a mixture of evenly aligned spindle cells, mature adipocytes, and ropey collagen. Most cases of spindle cell lipoma are found in the subcutaneous tissue, and intradermal spindle cell lipoma is rarely reported. We present a case of intradermal spindle cell lipoma in a 46-year-old female who presented with a 0.7-cm flesh-colored and dome-shaped nodule on the right temple that had developed 6 years ago. This mass was excised, and upon histopathologic examination, an unencapsulated lesion was located in the dermis, which consisted of bland spindle cells, scanty mature adipocytes, rare lipoblasts, and ropey collagen bundles with prominent basophilic myxoid stroma. Immunohistochemical staining showed diffuse positivity for CD34, negativity for the S-100 protein, and loss of retinoblastoma protein expression. Based on these features, intradermal low-fat spindle cell lipoma was diagnosed. No evidence of local recurrence was observed 4 months after excision. Intradermal low-fat spindle cell lipomas are extremely rare and can easily be mistaken for tumors that have similar clinical and histopathological findings. Herein, we report a globally rare case of an intradermal low-fat spindle cell lipoma.</p>","PeriodicalId":94298,"journal":{"name":"Annals of dermatology","volume":"35 Suppl 1","pages":"S10-S13"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0b/86/ad-35-S10.PMC10608367.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49687066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Young-Wook Ryoo, Ji-Min Yun, Hyun-Wook Kim, Sung-Ae Kim
{"title":"Early-Onset Generalized Pustular Psoriasis of Pregnancy Following Hydroxychloroquine Use.","authors":"Young-Wook Ryoo, Ji-Min Yun, Hyun-Wook Kim, Sung-Ae Kim","doi":"10.5021/ad.21.062","DOIUrl":"10.5021/ad.21.062","url":null,"abstract":"<p><p>Generalized pustular psoriasis of pregnancy (GPPP), characterized by widespread sterile pustules and erythematous patches with systemic symptoms such as fever, is a rare form of pustular psoriasis. GPPP typically occurs in the third trimester of pregnancy and can be triggered by various factors such as infections, hypocalcemia, and drugs including <i>N</i>-butyl-scopolammonium bromide. We report a rare case of new-onset GPPP in a 33-year-old multigravida female at 17 weeks' gestation, which occurred earlier than usual, after taking hydroxychloroquine for 3 weeks to treat systemic lupus erythematosus. She stopped her medications and was treated with systemic corticosteroid, but without improvement. Her medication was changed to systemic cyclosporine; her skin lesions improved, which completely resolved after delivery. This is the first case of GPPP developed following hydroxychloroquine use for systemic lupus erythematosus, which occurred earlier than usual and completely resolved after delivery. This case demonstrates that hydroxychloroquine can induce GPPP before the third trimester of pregnancy.</p>","PeriodicalId":94298,"journal":{"name":"Annals of dermatology","volume":"35 Suppl 1","pages":"S43-S47"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/59/27/ad-35-S43.PMC10608382.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49687059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yeon-Gu Choi, Hyeon Jeong Park, Sunmin Yim, Heun Joo Lee, Young Jun Choi, Won-Serk Kim, Ga-Young Lee
{"title":"Fixed Drug Eruption in a Patient Taking Valacyclovir without Cross-Reactivity to Acyclovir.","authors":"Yeon-Gu Choi, Hyeon Jeong Park, Sunmin Yim, Heun Joo Lee, Young Jun Choi, Won-Serk Kim, Ga-Young Lee","doi":"10.5021/ad.21.074","DOIUrl":"10.5021/ad.21.074","url":null,"abstract":"<p><p>Fixed drug eruption (FDE) is a well-defined hyperpigmented patch that recurs in a fixed location each time a particular drug is taken. Common causative agents of FDE are non-steroidal anti-inflammatory drugs, non-narcotic analgesics, sedatives, anticonvulsants, sulfonamides, and tetracycline. We report a 33-year-old male who presented with a recurrent, localized, brownish-to-erythematous macule and papules on the peri-philtrum area two hours after taking valacyclovir. Three episodes of valacyclovir ingestion for treatment of Herpes simplex virus infection provoked a similar skin rash at the same site. Histopathology results showed vacuolar degeneration in the basal layer of the epidermis, pigmentary incontinence, and perivascular inflammatory cell infiltration in the papillary dermis. Although patch test and skin prick test showed negative responses to acyclovir and valacyclovir, an intradermal test showed a positive reaction only to valacyclovir. The oral provocation test to acyclovir and valacyclovir showed a positive reaction only to valacyclovir. Through drug history, histopathological examination, patch test, intradermal test, and oral provocation test, we established a final diagnosis of FDE due to valacyclovir without cross-reactivity to acyclovir. To find alternative therapeutic drugs, we suggest diagnostic tests with not only the suspected drugs, but also other drugs in the same class.</p>","PeriodicalId":94298,"journal":{"name":"Annals of dermatology","volume":"35 Suppl 1","pages":"S55-S58"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f4/c5/ad-35-S55.PMC10608398.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49687061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hyeon Jeong Park, Won-Serk Kim, Seung-Wan Chae, Young-Jun Choi
{"title":"Insulin-Derived Cutaneous Amyloidosis: A Possible Complication of Repeated Insulin Injections.","authors":"Hyeon Jeong Park, Won-Serk Kim, Seung-Wan Chae, Young-Jun Choi","doi":"10.5021/ad.20.207","DOIUrl":"10.5021/ad.20.207","url":null,"abstract":"<p><p>Primary localized cutaneous amyloidosis (PLCA) is characterized by extracellular deposition of pathological fibril aggregation of proteins in the skin without systemic involvement. Macular amyloidosis, lichen (papular) amyloidosis, and nodular amyloidosis are three different subtypes of PLCA. Although the pathological mechanism of PLCA has not yet been clarified, it is assumed that a nucleus formation of amyloid fibril is formed due to repeated external stimulation, such as subcutaneous injection, which often poses diagnostic challenges. Herein, we present a 54-year-old Korean male patient with cutaneous localized amyloidosis which occurred after repeated local insulin injections, and discuss the relationship between insulin therapy in patients with diabetes mellitus and dermal amyloid deposition.</p>","PeriodicalId":94298,"journal":{"name":"Annals of dermatology","volume":"35 Suppl 1","pages":"S71-S75"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ee/b6/ad-35-S71.PMC10608354.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49687065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jang Hwan Jung, Sun Mun Jeong, Do Ik Kwon, Seol Hwa Seong, Joon Hee Kim, Jong Bin Park, Kee Suck Suh, Min Soo Jang
{"title":"Successful Treatment of Recalcitrant Palmoplantar Pustulosis with Guselkumab.","authors":"Jang Hwan Jung, Sun Mun Jeong, Do Ik Kwon, Seol Hwa Seong, Joon Hee Kim, Jong Bin Park, Kee Suck Suh, Min Soo Jang","doi":"10.5021/ad.21b.064","DOIUrl":"10.5021/ad.21b.064","url":null,"abstract":"Palmoplantar","PeriodicalId":94298,"journal":{"name":"Annals of dermatology","volume":"35 Suppl 1","pages":"S165-S167"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/98/83/ad-35-S165.PMC10608383.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49687081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}