Annals of dermatology最新文献_第6页

A Comparative Study on Clinico-Histopathological Features of Granulomatous Rosacea and Lupus Miliaris Disseminatus Faciei. 肉芽肿性红斑痤疮与散发性面部红斑狼疮临床组织病理学特征比较研究

Annals of dermatology Pub Date : 2024-02-01 DOI: 10.5021/ad.22.229

So Hee Park, Sang Woo Ahn, Seung Hee Jang, Seong Min Hong, Woo Jung Jin, Jung Eun Seol, So Young Jung, Hyojin Kim

引用次数: 0

Multi-Site Microbiome Composition in Atopic Dermatitis: A Case-Control Study. 特应性皮炎的多位点微生物组组成：病例对照研究

Annals of dermatology Pub Date : 2024-02-01 DOI: 10.5021/ad.22.117

Mitchell M Pitlick, Stephen Johnson, Roshini M Mullakary, Veena Taneja, Avni Y Joshi

引用次数: 0

A Case of Multiple Apocrine Hidrocystomas Accompanied by Inflammation on Bilateral Axillae. 一例双侧腋窝伴有炎症的多发性 Apocrine Hidrocystomas。

Annals of dermatology Pub Date : 2024-02-01 DOI: 10.5021/ad.21.145

Sangmin Choi, Bark-Lynn Lew, Soon-Hyo Kwon

引用次数: 0

Review of Scoring Systems for Hidradenitis Suppurativa. 肩周炎评分系统综述

Annals of dermatology Pub Date : 2024-02-01 DOI: 10.5021/ad.23.090

Youngbeom Kim, Jungsoo Lee, Hoon-Soo Kim, Hyun-Chang Ko, Byung-Soo Kim, Moon-Bum Kim, Kihyuk Shin

{"title":"Review of Scoring Systems for Hidradenitis Suppurativa.","authors":"Youngbeom Kim, Jungsoo Lee, Hoon-Soo Kim, Hyun-Chang Ko, Byung-Soo Kim, Moon-Bum Kim, Kihyuk Shin","doi":"10.5021/ad.23.090","DOIUrl":"10.5021/ad.23.090","url":null,"abstract":"Hidradenitis suppurativa (HS) is an inflammatory disorder characterized by chronic deep-seated nodules, abscesses, fistulae, sinus tracts, and scars in apocrine gland-bearing regions. Assessing its severity is challenging because of its clinical heterogeneity, lack of a standardized tool, and increasing severity scores. This article provides a chronological overview of HS grading scales to aid in the understanding and comparison of different scoring systems. A literature review of articles published in English on PubMed was conducted searched from 1989 to 2023. The review includes 15 scores that are the most relevant and widely used and acknowledges the existence of over 30 scoring systems for HS. The expanding landscape of HS scoring systems presents challenges when patients evaluated using different systems are compared. A universally accepted scoring system is required for consistent application across diverse populations. A comprehensive assessment should balance subjective and objective items, considering observer-reported signs and patient-reported symptoms to make meaningful treatment decisions.","PeriodicalId":94298,"journal":{"name":"Annals of dermatology","volume":"36 1","pages":"9-17"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10861310/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139704385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Eyelash Dyeing for Poliosis of Eyelashes in Patients With Vitiligo. 用睫毛染色法治疗白癜风患者的睫毛多发性硬化症。

Annals of dermatology Pub Date : 2024-02-01 DOI: 10.5021/ad.22.171

Hyun Jeong Ju, Soo Hyung Kim, Seo Gyeong Lee, Jung Min Bae

引用次数: 0

Actinidia polygama Water Extract (APWE) Protects Against UVB-Induced Photoaging via MAPK/AP-1 and TGFβ-Smad Pathway. 放线菌水提取物（APWE）通过 MAPK/AP-1 和 TGFβ-Smad 通路防止紫外线诱导的光老化

Annals of dermatology Pub Date : 2024-02-01 DOI: 10.5021/ad.23.010

Jung Min Lee, Su-Jin Park, Yu-Jin Kim, Su-Young Kim, Yoo-Na Jang, A Yeon Park, Seong-Hyun Ho, Dayoung Kim, Jung Ok Lee, Kwang-Ho Yoo, Beom Joon Kim

{"title":"Actinidia polygama Water Extract (APWE) Protects Against UVB-Induced Photoaging via MAPK/AP-1 and TGFβ-Smad Pathway.","authors":"Jung Min Lee, Su-Jin Park, Yu-Jin Kim, Su-Young Kim, Yoo-Na Jang, A Yeon Park, Seong-Hyun Ho, Dayoung Kim, Jung Ok Lee, Kwang-Ho Yoo, Beom Joon Kim","doi":"10.5021/ad.23.010","DOIUrl":"10.5021/ad.23.010","url":null,"abstract":"Background: Actinidia polygama (silver vine) has been used in oriental medicine to treat gout, rheumatoid arthritis, and inflammation. Actinidia polygama water extract (APWE) is named PB203.Objective: To investigate whether PB203 has anti-photoaging effects and to understand the molecular mechanism underlying such effects.Methods: The antioxidant effect was assessed by 1,1-diphenyl-2-picrylhydrazyl assay and 2',7'-dichlorodihydrofluorescein diacetate staining in ultraviolet B (UVB)-irradiated HaCaT cells with or without PB203 treatment. Type I collagen, matrix metalloproteinase-1 (MMP-1), tissue inhibitor of metalloproteinase (TIMP-1), hyaluronic acid (HA), hyaluronan synthase 1 (HAS1) and HAS2 levels were measuring by enzyme-linked immunosorbent assay or reverse transcription quantitative polymerase chain reaction. Also, we investigate the effects of PB203 on wrinkle formation, and the potential mechanisms underlying such effects were investigated in UVB-induced wrinkle mouse model mice.Results: PB203 alleviated the UVB-induced reactive oxygen species production, phosphorylation of JNK, ERK, and p38, and formation of AP-1. In addition, PB203 inhibited the decreases in type I collagen and TIMP-1 levels, and the increase in MMP-1 levels in UVB-exposed HaCaT cells. In UVB-induced wrinkle mouse model, PB203 inhibited the decreases in elastin and type I collagen levels as well as the increases in MMP-1 expression, wrinkle formation, and skin dehydration. Furthermore, PB203 increased the expression of filaggrin, HAS1, and HAS2, improving the skin barrier function.Conclusion: Taken together, we found that PB203 is as a potent candidate to serve as a functional ingredient or therapeutic agent to improve UVB-mediated skin aging.","PeriodicalId":94298,"journal":{"name":"Annals of dermatology","volume":"36 1","pages":"18-28"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10861301/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139704378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Importance of Stratum Corneum Acidification to Restore Skin Barrier Function in Eczematous Diseases. 角质层酸化对恢复湿疹患者皮肤屏障功能的重要性

Annals of dermatology Pub Date : 2024-02-01 DOI: 10.5021/ad.23.078

Eung Ho Choi, Hyun Kang

{"title":"Importance of Stratum Corneum Acidification to Restore Skin Barrier Function in Eczematous Diseases.","authors":"Eung Ho Choi, Hyun Kang","doi":"10.5021/ad.23.078","DOIUrl":"10.5021/ad.23.078","url":null,"abstract":"Skin barrier function relies on three essential components: stratum corneum (SC) lipids, natural moisturizing factors (NMFs), and the acidic pH of the SC surface. Three endogenous pathways contribute to acidity: free fatty acids from phospholipids, trans-urocanic acid from filaggrin (FLG), and the sodium-proton antiporter (NHE1) activity. An acidic SC environment boosts the activity of enzymes to produce ceramides, which are vital for skin health. Conversely, an elevated pH can lead to increased skin infections, reduced lipid-processing enzyme activity, impaired permeability barrier recovery, and compromised integrity and cohesion of the SC due to increased serine protease (SP) activity. Elevated SC pH is observed in neonatal, aged, and inflamed skin. In atopic dermatitis (AD), it results from decreased NMF due to reduced FLG degradation, decreased fatty acids from reduced lamellar body secretion, and reduced lactic acid due to decreased sweating. Moreover, the imbalance between SP and SP inhibitors disrupts barrier homeostasis. However, acidifying the SC can help restore balance and reduce SP activity. Acidic water bathing has been found to be safe and effective for AD. In three different AD murine models, SC acidification prevented the progression of AD to respiratory allergies. In aging skin, a decrease in NHE1 leads to an increased skin pH. Mild acidic skin care products or moisturizers containing NHE1 activators can normalize skin pH and improve barrier function. In conclusion, maintaining the acidity of the SC is crucial for healthy skin barrier function, leading to significant benefits for various skin conditions, such as AD and aging-related skin issues.","PeriodicalId":94298,"journal":{"name":"Annals of dermatology","volume":"36 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10861303/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139704383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Quality of Life and Psychosocial Impact on Female Pattern Hair Loss. 女性型脱发的生活质量和社会心理影响。

Annals of dermatology Pub Date : 2024-02-01 DOI: 10.5021/ad.23.082

Hye Won Hwang, Sunmin Ryou, Jun Hyeong Jeong, Jae Won Lee, Kyung-Ju Lee, Seon Bok Lee, Hyun-Tae Shin, Ji Won Byun, Jeonghyun Shin, Gwang Seong Choi

{"title":"The Quality of Life and Psychosocial Impact on Female Pattern Hair Loss.","authors":"Hye Won Hwang, Sunmin Ryou, Jun Hyeong Jeong, Jae Won Lee, Kyung-Ju Lee, Seon Bok Lee, Hyun-Tae Shin, Ji Won Byun, Jeonghyun Shin, Gwang Seong Choi","doi":"10.5021/ad.23.082","DOIUrl":"10.5021/ad.23.082","url":null,"abstract":"Background: Alopecia, a benign dermatologic condition affecting both genders, particularly harms female patients due to psychosocial effects. Female pattern hair loss (FPHL), the primary cause of hair loss in women, lacks sufficient Korean epidemiological studies examining its psychosocial aspects.Objective: This study aimed to explore FPHL's psychosocial impacts, including quality of life (QoL), depression, anxiety, medical consumption, and hair loss factors in Korean women.Methods: A total of 202 patients with FPHL were interviewed using a validated questionnaire to assess the QoL, psychological impact, and pattern of medical consumption. The severity of hair loss was evaluated using the \"basic and specific (BASP) classification\" by dermatologists. The Hair-Specific Skindex-29 (HSS29) was used to assess the QoL and Beck depression inventory (BDI), Beck anxiety inventory (BAI) to evaluate psychological aspects, and medical expenses and the number of clinic visits to determine medical consumption.Results: The global HSS29 score of FPHL was 40.97±18.92, indicating a notable impact on QoL. The mean BDI and BAI scores were 14.47 and 10.06, respectively. In multivariable regression analysis, HSS29, BDI, and BAI scores were most affected by the severity of hair loss (p<0.001).Conclusion: FPHL damages the psychosocial aspects of patients, such as QoL, depression, and medical consumption, according to the severity of hair loss.","PeriodicalId":94298,"journal":{"name":"Annals of dermatology","volume":"36 1","pages":"44-52"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10861302/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139704386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Ratio of Typical Clubbing in Pulled-Out Hairs as a Useful Marker in Predicting the Course of Alopecia Areata. 预测脱发病程的有用指标--拔出的头发中典型秃顶的比例

Annals of dermatology Pub Date : 2024-02-01 DOI: 10.5021/ad.23.026

So Hee Park, Hyojin Kim, Jong Uk Kim, Seong Min Hong, Sang Woo Ahn

{"title":"The Ratio of Typical Clubbing in Pulled-Out Hairs as a Useful Marker in Predicting the Course of Alopecia Areata.","authors":"So Hee Park, Hyojin Kim, Jong Uk Kim, Seong Min Hong, Sang Woo Ahn","doi":"10.5021/ad.23.026","DOIUrl":"10.5021/ad.23.026","url":null,"abstract":"Background: Analysis of hair microscopic morphology is a simple and less invasive method to differentiate alopecia areata (AA) from other alopecic diseases. However, there is limited information on the distribution of the microscopic characteristics.Objective: This study evaluated the microscopic morphological characteristics of pulled-out hair and their correlation with disease course in AA.Methods: Morphological characteristics of pulled-out hair were classified into 5 categories: the presence of typical clubbing, surface undulation, tapering, breakage, and depigmentation in proximal hair shaft. Clinical course of AA was investigated through assessment of Severity of Alopecia Tool (SALT) score (initial score, maximal score and difference of them [ΔSALT]).Results: Among 1,272 pulled-out hairs (n=179) obtained at initial visit, depigmentation (59.5%) was the most common, followed by loss of typical clubbing (57.2%) and surface undulation (55.2%). The percentage of loss of typical clubbing and proximal tapering was significantly higher in severe type of AA, younger age of onset and shorter disease duration. The ratio of typical clubbing (<50% vs. ≥50%) was associated with difference in maximal score and ΔSALT (p<0.05). Strong activity group (pulled-out hair ≥10, n=33) showed difference in clinical course (maximal score, ΔSALT) as well as distribution of microscopic features (loss of typical clubbing) compared with those in non-strong activity group. The ratio of typical clubbing significantly increased at follow-up than initially in strong activity group (p<0.05).Conclusion: Microscopic hair morphology, especially loss of typical clubbing and proximal tapering, could be useful tool to predict the course of AA.","PeriodicalId":94298,"journal":{"name":"Annals of dermatology","volume":"36 1","pages":"29-34"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10861307/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139704387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of a Precision Cryotherapy Device with Temperature-Adjustability on Mice with Cutibacterium acnes-Induced Inflammation. 可调节温度的精密冷冻治疗仪对痤疮杆菌诱发炎症小鼠的影响

Annals of dermatology Pub Date : 2023-12-01 DOI: 10.5021/ad.22.054

Mi Hee Kwack, Seongjin Lee, Gi Ung Ha, Gun-Ho Kim, Weon Ju Lee

引用次数: 0