Annals of dermatology最新文献_第5页

Correlation Between Nail Thickness and Onychomycosis: Misuse of Antifungal Agents in Patients With Thick Nails. 指甲厚度与甲癣之间的相关性：厚指甲患者滥用抗真菌药物。

Annals of dermatology Pub Date : 2024-04-01 DOI: 10.5021/ad.22.130

Joon Ki Kim, Hyun Cheol Chung, Eun Ji Chun, Sangseok Kim, Chul Woo Kim

引用次数: 0

Rare Cutaneous Soft Tissue Sarcomas Treated With Slow Mohs Micrographic Surgery: Ten Years' Experience at a Single Institution. 罕见皮肤软组织肉瘤的慢速莫氏显微手术治疗：一家机构的十年经验。

Annals of dermatology Pub Date : 2024-04-01 DOI: 10.5021/ad.21.101

Sul Hee Lee, Kee Yang Chung, Sooyie Choi, Thanya Techapichetvanich

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Consensus Report on Truncal Acne: The Korean Acne and Rosacea Society Experts Panel. 截肢性痤疮共识报告：韩国痤疮和红斑痤疮协会专家小组。

Annals of dermatology Pub Date : 2024-02-01 DOI: 10.5021/ad.23.057

Joo Yeon Ko, Chang Hwa Song, Kwang Joong Kim, Nack In Kim, Jung Eun Kim, Hei Sung Kim, Young Suck Ro, Kui Young Park, Mi-Youn Park, Dae Hun Suh, Kihyuck Shin, Min Kyung Shin, Hyo Hyun Ahn, Woo Jin Lee, Weon Ju Lee, Ju Hee Lee, Jee Bum Lee, Hae Woong Lee, Hee Jung Lee, Min Soo Jang, Seung Hyun Cheong, Soyun Cho, Yu Sung Choi, You Won Choi, Hoon Choi, Mi Woo Lee

{"title":"Consensus Report on Truncal Acne: The Korean Acne and Rosacea Society Experts Panel.","authors":"Joo Yeon Ko, Chang Hwa Song, Kwang Joong Kim, Nack In Kim, Jung Eun Kim, Hei Sung Kim, Young Suck Ro, Kui Young Park, Mi-Youn Park, Dae Hun Suh, Kihyuck Shin, Min Kyung Shin, Hyo Hyun Ahn, Woo Jin Lee, Weon Ju Lee, Ju Hee Lee, Jee Bum Lee, Hae Woong Lee, Hee Jung Lee, Min Soo Jang, Seung Hyun Cheong, Soyun Cho, Yu Sung Choi, You Won Choi, Hoon Choi, Mi Woo Lee","doi":"10.5021/ad.23.057","DOIUrl":"10.5021/ad.23.057","url":null,"abstract":"Background: More than half of acne patients have truncal acne on their chest, back, and shoulders. However, since most studies on acne have focused on the face, data on clinical characteristics and proper management for truncal acne are insufficient.Objective: To establish a Korean Acne Rosacea Society (KARS) consensus for experts' perception and treatment patterns of truncal acne.Methods: We conducted two rounds of the Dephi technique to gather expert opinion and reach a consensus on truncal acne. The first round comprised 48 questionnaires focusing on various aspects such as epidemiology, clinical features, diagnosis, treatment, prognosis and more, while second rounds consisted of 26 questionnaires.Results: A total of 36 dermatologists (36/38 KARS members, 94.7%) completed this survey. In the first-round survey, consensus was reached on 20 out of the 48 questions (41.7%). In the second-round questionnaire, consensus was achieved on 9 of the 26 questions (34.6%). The most unresponsive lesion to truncal acne treatment was scars (atrophic/hypertrophic). The most commonly used treatments for each non-inflammatory and inflammatory truncal acne lesions were selected to use topical retinoids (78.1% of the responders) and oral antibiotics (93.8% of the responders).Conclusion: Our study has yielded valuable insights into the epidemiology, clinical manifestations, diagnosis, treatment, and quality of life of patients with truncal acne. We anticipate that this study will inspire further comprehensive research for individuals with truncal acne.","PeriodicalId":94298,"journal":{"name":"Annals of dermatology","volume":"36 1","pages":"35-43"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10861305/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139704381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Comparative Study on Clinico-Histopathological Features of Granulomatous Rosacea and Lupus Miliaris Disseminatus Faciei. 肉芽肿性红斑痤疮与散发性面部红斑狼疮临床组织病理学特征比较研究

Annals of dermatology Pub Date : 2024-02-01 DOI: 10.5021/ad.22.229

So Hee Park, Sang Woo Ahn, Seung Hee Jang, Seong Min Hong, Woo Jung Jin, Jung Eun Seol, So Young Jung, Hyojin Kim

引用次数: 0

Multi-Site Microbiome Composition in Atopic Dermatitis: A Case-Control Study. 特应性皮炎的多位点微生物组组成：病例对照研究

Annals of dermatology Pub Date : 2024-02-01 DOI: 10.5021/ad.22.117

Mitchell M Pitlick, Stephen Johnson, Roshini M Mullakary, Veena Taneja, Avni Y Joshi

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A Case of Multiple Apocrine Hidrocystomas Accompanied by Inflammation on Bilateral Axillae. 一例双侧腋窝伴有炎症的多发性 Apocrine Hidrocystomas。

Annals of dermatology Pub Date : 2024-02-01 DOI: 10.5021/ad.21.145

Sangmin Choi, Bark-Lynn Lew, Soon-Hyo Kwon

引用次数: 0

Review of Scoring Systems for Hidradenitis Suppurativa. 肩周炎评分系统综述

Annals of dermatology Pub Date : 2024-02-01 DOI: 10.5021/ad.23.090

Youngbeom Kim, Jungsoo Lee, Hoon-Soo Kim, Hyun-Chang Ko, Byung-Soo Kim, Moon-Bum Kim, Kihyuk Shin

{"title":"Review of Scoring Systems for Hidradenitis Suppurativa.","authors":"Youngbeom Kim, Jungsoo Lee, Hoon-Soo Kim, Hyun-Chang Ko, Byung-Soo Kim, Moon-Bum Kim, Kihyuk Shin","doi":"10.5021/ad.23.090","DOIUrl":"10.5021/ad.23.090","url":null,"abstract":"Hidradenitis suppurativa (HS) is an inflammatory disorder characterized by chronic deep-seated nodules, abscesses, fistulae, sinus tracts, and scars in apocrine gland-bearing regions. Assessing its severity is challenging because of its clinical heterogeneity, lack of a standardized tool, and increasing severity scores. This article provides a chronological overview of HS grading scales to aid in the understanding and comparison of different scoring systems. A literature review of articles published in English on PubMed was conducted searched from 1989 to 2023. The review includes 15 scores that are the most relevant and widely used and acknowledges the existence of over 30 scoring systems for HS. The expanding landscape of HS scoring systems presents challenges when patients evaluated using different systems are compared. A universally accepted scoring system is required for consistent application across diverse populations. A comprehensive assessment should balance subjective and objective items, considering observer-reported signs and patient-reported symptoms to make meaningful treatment decisions.","PeriodicalId":94298,"journal":{"name":"Annals of dermatology","volume":"36 1","pages":"9-17"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10861310/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139704385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Eyelash Dyeing for Poliosis of Eyelashes in Patients With Vitiligo. 用睫毛染色法治疗白癜风患者的睫毛多发性硬化症。

Annals of dermatology Pub Date : 2024-02-01 DOI: 10.5021/ad.22.171

Hyun Jeong Ju, Soo Hyung Kim, Seo Gyeong Lee, Jung Min Bae

引用次数: 0

Actinidia polygama Water Extract (APWE) Protects Against UVB-Induced Photoaging via MAPK/AP-1 and TGFβ-Smad Pathway. 放线菌水提取物（APWE）通过 MAPK/AP-1 和 TGFβ-Smad 通路防止紫外线诱导的光老化

Annals of dermatology Pub Date : 2024-02-01 DOI: 10.5021/ad.23.010

Jung Min Lee, Su-Jin Park, Yu-Jin Kim, Su-Young Kim, Yoo-Na Jang, A Yeon Park, Seong-Hyun Ho, Dayoung Kim, Jung Ok Lee, Kwang-Ho Yoo, Beom Joon Kim

{"title":"Actinidia polygama Water Extract (APWE) Protects Against UVB-Induced Photoaging via MAPK/AP-1 and TGFβ-Smad Pathway.","authors":"Jung Min Lee, Su-Jin Park, Yu-Jin Kim, Su-Young Kim, Yoo-Na Jang, A Yeon Park, Seong-Hyun Ho, Dayoung Kim, Jung Ok Lee, Kwang-Ho Yoo, Beom Joon Kim","doi":"10.5021/ad.23.010","DOIUrl":"10.5021/ad.23.010","url":null,"abstract":"Background: Actinidia polygama (silver vine) has been used in oriental medicine to treat gout, rheumatoid arthritis, and inflammation. Actinidia polygama water extract (APWE) is named PB203.Objective: To investigate whether PB203 has anti-photoaging effects and to understand the molecular mechanism underlying such effects.Methods: The antioxidant effect was assessed by 1,1-diphenyl-2-picrylhydrazyl assay and 2',7'-dichlorodihydrofluorescein diacetate staining in ultraviolet B (UVB)-irradiated HaCaT cells with or without PB203 treatment. Type I collagen, matrix metalloproteinase-1 (MMP-1), tissue inhibitor of metalloproteinase (TIMP-1), hyaluronic acid (HA), hyaluronan synthase 1 (HAS1) and HAS2 levels were measuring by enzyme-linked immunosorbent assay or reverse transcription quantitative polymerase chain reaction. Also, we investigate the effects of PB203 on wrinkle formation, and the potential mechanisms underlying such effects were investigated in UVB-induced wrinkle mouse model mice.Results: PB203 alleviated the UVB-induced reactive oxygen species production, phosphorylation of JNK, ERK, and p38, and formation of AP-1. In addition, PB203 inhibited the decreases in type I collagen and TIMP-1 levels, and the increase in MMP-1 levels in UVB-exposed HaCaT cells. In UVB-induced wrinkle mouse model, PB203 inhibited the decreases in elastin and type I collagen levels as well as the increases in MMP-1 expression, wrinkle formation, and skin dehydration. Furthermore, PB203 increased the expression of filaggrin, HAS1, and HAS2, improving the skin barrier function.Conclusion: Taken together, we found that PB203 is as a potent candidate to serve as a functional ingredient or therapeutic agent to improve UVB-mediated skin aging.","PeriodicalId":94298,"journal":{"name":"Annals of dermatology","volume":"36 1","pages":"18-28"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10861301/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139704378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Importance of Stratum Corneum Acidification to Restore Skin Barrier Function in Eczematous Diseases. 角质层酸化对恢复湿疹患者皮肤屏障功能的重要性

Annals of dermatology Pub Date : 2024-02-01 DOI: 10.5021/ad.23.078

Eung Ho Choi, Hyun Kang

{"title":"Importance of Stratum Corneum Acidification to Restore Skin Barrier Function in Eczematous Diseases.","authors":"Eung Ho Choi, Hyun Kang","doi":"10.5021/ad.23.078","DOIUrl":"10.5021/ad.23.078","url":null,"abstract":"Skin barrier function relies on three essential components: stratum corneum (SC) lipids, natural moisturizing factors (NMFs), and the acidic pH of the SC surface. Three endogenous pathways contribute to acidity: free fatty acids from phospholipids, trans-urocanic acid from filaggrin (FLG), and the sodium-proton antiporter (NHE1) activity. An acidic SC environment boosts the activity of enzymes to produce ceramides, which are vital for skin health. Conversely, an elevated pH can lead to increased skin infections, reduced lipid-processing enzyme activity, impaired permeability barrier recovery, and compromised integrity and cohesion of the SC due to increased serine protease (SP) activity. Elevated SC pH is observed in neonatal, aged, and inflamed skin. In atopic dermatitis (AD), it results from decreased NMF due to reduced FLG degradation, decreased fatty acids from reduced lamellar body secretion, and reduced lactic acid due to decreased sweating. Moreover, the imbalance between SP and SP inhibitors disrupts barrier homeostasis. However, acidifying the SC can help restore balance and reduce SP activity. Acidic water bathing has been found to be safe and effective for AD. In three different AD murine models, SC acidification prevented the progression of AD to respiratory allergies. In aging skin, a decrease in NHE1 leads to an increased skin pH. Mild acidic skin care products or moisturizers containing NHE1 activators can normalize skin pH and improve barrier function. In conclusion, maintaining the acidity of the SC is crucial for healthy skin barrier function, leading to significant benefits for various skin conditions, such as AD and aging-related skin issues.","PeriodicalId":94298,"journal":{"name":"Annals of dermatology","volume":"36 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10861303/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139704383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0