Cameron Goertzen, Erin Goertzen, Maryam Zanjir, Christopher Dare, Amir Azarpazhooh, Michelle Wong
{"title":"Comparison of Anesthetics for Laryngeal Mask Airway Insertion: A Network Meta-Analysis.","authors":"Cameron Goertzen, Erin Goertzen, Maryam Zanjir, Christopher Dare, Amir Azarpazhooh, Michelle Wong","doi":"10.2344/22-00033","DOIUrl":"10.2344/22-00033","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to establish which anesthetic agents are associated with minimized adverse outcomes during laryngeal mask airway (LMA) insertion.</p><p><strong>Methods: </strong>Databases were searched for randomized controlled trials (RCTs) with American Society of Anesthesiologists I or II adult patients (≥15 years of age) receiving general anesthesia (GA) with an LMA. Propofol only was the comparator to other anesthetics used during LMA insertion. The primary outcome was prolonged apnea, and secondary outcomes were adverse airway events, LMA insertion failure, inadequate depth of anesthesia, and hemodynamic events. A network meta-analysis was conducted to estimate the treatment effects (odds ratios, 95% credible intervals, and surface under the cumulative ranking curve [SUCRA]).</p><p><strong>Results: </strong>A total of 28 anesthetic combinations used on 4695 patients for GA induction and LMA insertion were examined across 53 RCTs. Overall, there was an apnea incidence rate of 33.3% (849 of 2548) with a mean time of 3.74 ± 3.56 minutes (n = 3091). Propofol + dexmedetomidine had the highest overall summed score of SUCRA ranks in reducing adverse outcomes (apnea incidence: SUCRA = 37%, apnea time: SUCRA = 66%, airway adverse event: SUCRA = 67%, insertion failure: SUCRA = 73%, inadequate depth of anesthesia: SUCRA = 84%). In comparison among all propofol combinations, propofol alone ranked lowest for overall summed score of SUCRA in reducing adverse outcomes (apnea incidence: SUCRA = 47%, apnea time: SUCRA = 71%, airway adverse event: SUCRA = 9%, insertion failure: SUCRA = 20%, inadequate depth of anesthesia: SUCRA = 9%).</p><p><strong>Conclusion: </strong>All anesthetic combinations, other than those with thiopental, reduced adverse outcomes as compared with propofol alone. The combination of propofol and dexmedetomidine infused over 10 minutes ranked as the most effective for reducing adverse outcomes during LMA insertion.</p>","PeriodicalId":94296,"journal":{"name":"Anesthesia progress","volume":"71 2","pages":"58-75"},"PeriodicalIF":0.0,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11259371/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142584508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tomoaki Ujita, Toru Yamamoto, Yutaka Tanaka, Shigenobu Kurata, Kenji Seo
{"title":"Tracheal Stenosis Detected During Endotracheal Intubation in a Patient With Down Syndrome.","authors":"Tomoaki Ujita, Toru Yamamoto, Yutaka Tanaka, Shigenobu Kurata, Kenji Seo","doi":"10.2344/anpr-63-16-65","DOIUrl":"10.2344/anpr-63-16-65","url":null,"abstract":"<p><p>We report a case in which tracheal stenosis was discovered during endotracheal intubation. A 19-year-old woman with Down syndrome was scheduled to undergo treatment of multiple dental caries under intubated general anesthesia. During the first general anesthetic, we felt some resistance while advancing the endotracheal tube through the trachea. Prior to a second general anesthetic 2 years later, we performed 3-dimensional computed tomography to evaluate the tracheal stenosis and devised a strategy that established an airway without advancing the endotracheal tube over the stenotic lesion. Careful attention is required when performing endotracheal intubation because patients with Down syndrome sometimes have tracheal stenosis.</p>","PeriodicalId":94296,"journal":{"name":"Anesthesia progress","volume":"71 2","pages":"85-86"},"PeriodicalIF":0.0,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11259361/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142585046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Joint Meeting of the IFDAS 17th Triennial Congress and the ADSA Annual Session Held in Las Vegas.","authors":"Jason Brady","doi":"10.2344/025134","DOIUrl":"10.2344/025134","url":null,"abstract":"","PeriodicalId":94296,"journal":{"name":"Anesthesia progress","volume":"71 2","pages":"101-103"},"PeriodicalIF":0.0,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11259363/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142584947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Toru Yamamoto, Yuhei Koyama, Yutaka Tanaka, Kenji Seo
{"title":"Delayed Rocuronium Onset in a Patient Taking Levetiracetam for Epilepsy: A Case Report.","authors":"Toru Yamamoto, Yuhei Koyama, Yutaka Tanaka, Kenji Seo","doi":"10.2344/23-00018","DOIUrl":"10.2344/23-00018","url":null,"abstract":"<p><p>Emerging evidence suggests that many conventional anticonvulsants, such as carbamazepine, phenytoin, and valproic acid, could cause cross-resistance to nondepolarizing muscle relaxants. However, there are few reports describing the interactions between levetiracetam and rocuronium. This case report describes the delayed onset of rocuronium in an adult patient with intractable epilepsy on long-term levetiracetam therapy. A 33-year-old man was scheduled for extraction of third molars and restorative dental treatment. His daily levetiracetam was continued preoperatively, and after a slow mask induction, rocuronium (20 mg; 0.66 mg/kg) was administered. Muscle relaxation was monitored by train-of-four (TOF) stimulation using the adductor muscle of the thumb. However, it took more than 9 minutes to finally obtain a TOF count of 0. This case report highlights that patients with intractable epilepsy taking levetiracetam may have resistance to rocuronium and should be carefully monitored to avoid harm triggered by prematurely initiated intubation maneuvers.</p>","PeriodicalId":94296,"journal":{"name":"Anesthesia progress","volume":"71 2","pages":"76-80"},"PeriodicalIF":0.0,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11259367/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142584631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"In Memoriam: Dr Stuart E. LieblichOctober 14, 1955-February 28, 2024.","authors":"Robert C Bosack","doi":"10.2344/anpr-566035","DOIUrl":"10.2344/anpr-566035","url":null,"abstract":"","PeriodicalId":94296,"journal":{"name":"Anesthesia progress","volume":"71 2","pages":"106"},"PeriodicalIF":0.0,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11259368/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144683965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"General Anesthetic Management of a Patient With Spondyloepiphyseal Dysplasia Congenita Undergoing Palatoplasty Revision.","authors":"Hiroka Hattori, Aiji Sato Boku, Mayuko Kanazawa, Erika Harada, Mami Asai, Yuko Shikama, Hiroko Kobayashi, Makoto Hirohata, Naoko Tachi, Masahiro Okuda","doi":"10.2344/23-0005","DOIUrl":"10.2344/23-0005","url":null,"abstract":"<p><p>Spondyloepiphyseal dysplasia congenita (SEDC) is a type of short-limbed dwarfism characterized by platyspondylia, delayed metaphyseal ossification, and irregularly shaped bones. Anesthetic issues in patients with SEDC have reportedly included airway stenosis caused by laryngotracheal hypoplasia, ventilation difficulty due to facial hypoplasia, and intubation difficulty attributed to microgenia. Furthermore, atlantoaxial instability can lead to cervical dislocation due to excessive or violent manipulation of the head and neck. We present the case of a 5-year-old girl with SEDC scheduled for palatoplasty revision. Airway difficulties were anticipated because of microgenia and the cervical collar she wore for atlantoaxial instability. However, mask ventilation and video laryngoscopy proved relatively easy. The patient was placed in Trendelenburg position (approximately 10°) without head tilt for surgical access. A combination of formulas based on the patient's age and height was used to determine tracheal tube size. However, the 4.5-mm oral Ring, Adair, Elwyn (RAE) tube selected resulted in 1-lung intubation when the tube bend was fixed at the lip, requiring further depth adjustment. Successful anesthetic management of this patient with SEDC incorporated several factors, including an individualized airway management plan, use of a video laryngoscope, careful posturing to avoid excessive cervical strain, and appropriate tube sizing and positioning.</p>","PeriodicalId":94296,"journal":{"name":"Anesthesia progress","volume":"71 1","pages":"19-23"},"PeriodicalIF":0.0,"publicationDate":"2024-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11101291/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142583404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Review of Current Literature of Interest to the Office-Based Anesthesiologist.","authors":"Mark A Saxen, Craig P McKenzie","doi":"10.2344/348194","DOIUrl":"10.2344/348194","url":null,"abstract":"","PeriodicalId":94296,"journal":{"name":"Anesthesia progress","volume":"71 1","pages":"53-55"},"PeriodicalIF":0.0,"publicationDate":"2024-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11101289/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142580816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}