Pronounced QT Prolongation During General Anesthesia in a Child with Left Ventricular Noncompaction Cardiomyopathy: A Case Report.

Mika Nishikawa, Kazumi Takaishi, Marina Takata, Osamu Sasajima, Shigeki Joseph Luke Fujiwara, Satoru Eguchi, Shinji Kawahito
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Abstract

We report the case of an 8-year-old boy with left ventricular noncompaction cardiomyopathy (LVNC) and QT prolongation who experienced further prolongation of the QTc during general anesthesia for extraction of a maxillary mesiodens. Pronounced prolongation of the QTc was observed after induction of general anesthesia with thiamylal and during emergence. No notable fluctuations in blood pressure, heart rate, and estimated continuous cardiac output were observed. We considered it likely that the QT prolongation was triggered by thiamylal and increased sympathetic nervous system activity. During general anesthesia for children with LVNC and QT prolongation, it is necessary to monitor intraoperative hemodynamic fluctuations and prepare for the possible occurrence of arrhythmias.

一例左心室非致密性心肌病患儿全麻期间明显QT延长的病例报告。
我们报告了一例患有左心室非致密性心肌病(LVNC)和QT延长的8岁男孩的病例,他在上颌近中碘酸根拔除的全身麻醉期间经历了QTc的进一步延长。硫胺脲全麻诱导后和苏醒期观察到QTc明显延长。没有观察到血压、心率和估计的持续心输出量的显著波动。我们认为QT延长可能是由硫胺醇和交感神经系统活动增加引起的。在LVNC和QT延长儿童全身麻醉期间,有必要监测术中血液动力学波动,并为可能发生的心律失常做好准备。
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