African health sciences最新文献_第9页

Prevalence and determinant factors of low birth weight in Marrakesh province, Morocco: cross sectorial survey 摩洛哥马拉喀什省出生体重不足的发生率和决定因素：跨部门调查

African health sciences Pub Date : 2024-07-11 DOI: 10.4314/ahs.v24i2.32

Soufiane Elmoussaoui, K. Kaoutar, Ahmed Chetoui, Abdeslam El Kardoudi, F. Chigr, Mounir Borrous, M. Najimi

{"title":"Prevalence and determinant factors of low birth weight in Marrakesh province, Morocco: cross sectorial survey","authors":"Soufiane Elmoussaoui, K. Kaoutar, Ahmed Chetoui, Abdeslam El Kardoudi, F. Chigr, Mounir Borrous, M. Najimi","doi":"10.4314/ahs.v24i2.32","DOIUrl":"https://doi.org/10.4314/ahs.v24i2.32","url":null,"abstract":"Background: Low Birth Weight (LBW) is considered as the marker of infant wellbeing and the fundamental focus of infant health policy. The objective of this survey was to determine the prevalence of LBW and its associated factors in term new borns. \u0000Methods: The data was collected using an interviewer administered questionnaire. Both bivariate and multivariate logistic regression analyses were used to identify factors associated with LBW. \u0000Results: Totally 350 mother–newborn pairs were participated in this study. Out of this, 16.7% of term neonates were found to be LBW. Of note, employed mothers, mothers having birth interval less or equal to two years, women with previous history of low birth weight and mothers living in passive smoking conditions at home during pregnancy were more likely to have low birth weight babies. \u0000Conclusion: The prevalence of LBW in our study could be considered as relatively high. It is recommended that special attention should be given to pregnant mothers to get adequate rest, attentional diet, and antenatal services available and accessible to all pregnant women. \u0000Keywords: Low birth weight; newborn; mothers; Marrakesh; Morocco.","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"124 s440","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141835050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Factors influencing utilisation of cervical cancer screening services among HIV positive women attending care and treatment centres in Kinondoni municipality, Dar es Salaam, Tanzania 影响坦桑尼亚达累斯萨拉姆省 Kinondoni 市护理和治疗中心的 HIV 阳性妇女利用宫颈癌筛查服务的因素

African health sciences Pub Date : 2024-07-11 DOI: 10.4314/ahs.v24i2.5

Eliena Kisaka, T. Kabalimu, I. Semali, Y. Mashalla

{"title":"Factors influencing utilisation of cervical cancer screening services among HIV positive women attending care and treatment centres in Kinondoni municipality, Dar es Salaam, Tanzania","authors":"Eliena Kisaka, T. Kabalimu, I. Semali, Y. Mashalla","doi":"10.4314/ahs.v24i2.5","DOIUrl":"https://doi.org/10.4314/ahs.v24i2.5","url":null,"abstract":"Background: Cervical cancer is among the leading causes of cancer-related deaths among HIV+ve women. \u0000Objective: To determine factors influencing utilisation of cervical cancer screening among HIV+ve women attending Cancer Treatment and Care in Kinondoni Municipality, Dar es Salaam. \u0000Methods: Cross-sectional study among HIV+ve women was carried out between September and October 2021; collected using a standardised questionnaire. Descriptive statistics, bivariate and multivariate analyses were used to determine cervical cancer extent and association of predictors of cervical cancer screening. \u0000Results: 230 HIV+ve women aged 21–60 years were interviewed. Only 47% had screened for cervical cancer. Low knowledge of HIV+ve as risk significantly associated with less likelihood to screen for cervical cancer [AOR 0.49, 95% CI (0.253-0.957, P = 0.037)]. Parity of 3 or more was twice likely to screen for cervical cancer [AOR 2.124, 95% CI (1.012-4.456, P = 0.046)]; and housewives were 2.5 more likely to screen for cervical cancer [AOR 2.594, 95% CI (1.149-5.853, P = 0.002)]. Lack of knowledge on preventive measures was less associated with likelihood to screen [AOR 0.114, 95% CI (0.013-0.972, P = 0.047)]. \u0000Conclusion: Lack of knowledge on HIV+ve and prevention, age and parity are likely to influence utilisation of cervical cancer screening services. \u0000Keywords: Cervical cancer; HIV positive women.","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"74 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141834546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluating the knowledge, practice and experience about management of Parkinson’s Disease among physiotherapists in Ghana: a cross-sectional survey 评估加纳物理治疗师对帕金森病管理的知识、实践和经验：横断面调查

African health sciences Pub Date : 2024-07-11 DOI: 10.4314/ahs.v24i2.45

Mary Agoriwo

{"title":"Evaluating the knowledge, practice and experience about management of Parkinson’s Disease among physiotherapists in Ghana: a cross-sectional survey","authors":"Mary Agoriwo","doi":"10.4314/ahs.v24i2.45","DOIUrl":"https://doi.org/10.4314/ahs.v24i2.45","url":null,"abstract":"Background: Parkinson’s disease (PD) presents with numerous functional disabilities which require specific expertise for effective management. \u0000Objective: To describe the level of PD-specific expertise among physiotherapists (PTs) in Ghana and establish the association between the level of expertise, practice duration and number of persons with PD treated annually. \u0000Methods: A cross-sectional survey was conducted among PTs. A 25-item questionnaire was validated, piloted and distributed to PTs during an annual general meeting. Microsoft Excel 2016 and the Kruskal-Wallis test were used to perform descriptive statistical analysis and test for association respectively. \u0000Results: There was a 70% (n=42/60) response rate. Overall, 50%-90% of the participating PTs had limited knowledge about the cardinal motor signs, non-motor symptoms, motor complications of PD and setting of treatment goals. There was no significant association between participants’ level of PD-Specific expertise and practice duration and number of persons with PD treated annually. \u0000Conclusion: The PTs exhibited inadequate knowledge about PD and its management. This limitation was not influenced by PTs practice duration or number of persons with PD treated annually. The immediate need for PD-specific training for PTs in Ghana is crucial to enhance PTs’ expertise in the management of persons with PD. \u0000Keywords: Parkinson’s disease; physiotherapy; professional knowledge.","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"20 2‐3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141834665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Causes, management outcome, and associated factors in patients admitted with a diagnosis of intestinal obstruction to Ambo University Referral Hospital: a 3-year retrospective chart review 安博大学转诊医院收治的诊断为肠梗阻的患者的病因、治疗结果和相关因素：3 年回顾性病历审查

African health sciences Pub Date : 2024-07-11 DOI: 10.4314/ahs.v24i2.36

Erko Beyene, Meti Negassa

{"title":"Causes, management outcome, and associated factors in patients admitted with a diagnosis of intestinal obstruction to Ambo University Referral Hospital: a 3-year retrospective chart review","authors":"Erko Beyene, Meti Negassa","doi":"10.4314/ahs.v24i2.36","DOIUrl":"https://doi.org/10.4314/ahs.v24i2.36","url":null,"abstract":"Background: Intestinal obstruction is a major cause of surgical admissions in African countries. In this study, we assessed the causes, management outcome and associated factors among patients admitted with the diagnosis of intestinal obstruction to AURH. \u0000Methods: A retrospective chart review was conducted on all patients admitted to AURH with the diagnosis of intestinal obstruction from September 2017G.C. to August 2020G.C. \u0000Results: Sigmoid volvulus and Adhesions were the most common causes of large bowel obstruction and small bowel obstruction, respectively accounting for 85.4% and 37.3% of cases. 203(69.3%) patients were managed operatively among which 70(23.9%) had unfavorable outcome. The mortality rate of intestinal obstruction in our study population was 5.5%. Factors which had significant association with management outcome were length of hospital stay, history of abdominal surgery and history of intestinal obstruction. \u0000Conclusion: The most common causes of intestinal obstruction in our study population were similar to the one’s implicated in other studies done in the low-income countries. There is relatively high rate of unfavorable outcome which calls for further investigation as to why this is occurring. We recommend also interventions to be implemented to reduce the causes of morbidity and mortality related to intestinal obstruction found in this study. \u0000Keywords: Intestinal obstruction; management outcome; causes of intestinal obstruction.","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"8 2‐3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141834836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of socio-economic factors on malaria prevalence in a Peri-urban setting in Vihiga County, Western Kenya Highlands 社会经济因素对肯尼亚西部高地维希加县近郊地区疟疾发病率的影响

African health sciences Pub Date : 2024-07-11 DOI: 10.4314/ahs.v24i2.19

Beatrice Aleyo Muzame, Elizabeth Omukunda, David H Mulama, Patrick Okoth

{"title":"Effect of socio-economic factors on malaria prevalence in a Peri-urban setting in Vihiga County, Western Kenya Highlands","authors":"Beatrice Aleyo Muzame, Elizabeth Omukunda, David H Mulama, Patrick Okoth","doi":"10.4314/ahs.v24i2.19","DOIUrl":"https://doi.org/10.4314/ahs.v24i2.19","url":null,"abstract":"Background: Malaria is the leading cause of mortality in sub-Saharan Africa. \u0000Objective: The study assessed the effect of socio-economic factors on high malaria prevalence in a peri-urban setting in Vihiga County, Western Kenya highlands aimed at strengthening implementation of cost-effective malaria control strategies at household level. \u0000Method: A longitudinal study was carried out in the study area from December 2019 to November 2020. From patients who presented themselves at Mbale Provincial Rural Training health center for various treatments, 768 malaria confirmed patients were recruited and signed consent before the study commenced. Data was collected using microscopy and structured questionnaires used to stratify malaria patients into socio-economic status and their residence. Data was presented through graphs, frequency, analyzed using linear regression and correlation. P-value ≤ 0.05as considered statistically significant. \u0000Results: Linear regression analysis showed effect of socio-economic factors on malaria prevalence was statistically significant, R2 = 0.061, [F (7,760) = 7.063], p < 0.0001). Level of education, wealth, land size, house type and house ventilation were statistically significant to malaria prevalence as opposed to salary and household size. \u0000Conclusion: Socio-economic factors influenced malaria prevalence in the study area. Implementation of cost-effective malaria control strategies should be strengthened at household level. \u0000Keywords: Malaria prevalence; socio-economic factors; malaria control strategies; mosquitoes breeding sites; household level.","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"74 s1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141834865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A comparative assessment of CD4 recovery in a cohort of patients on different HAART regimens in a Nigerian tertiary healthcare facility 尼日利亚一家三级医疗机构对一组接受不同 HAART 治疗方案的患者的 CD4 恢复情况进行比较评估

African health sciences Pub Date : 2024-07-11 DOI: 10.4314/ahs.v24i2.3

P. Onah, C. Idoko, Aliyu Kai'gama, Siyaka Abdulateef

{"title":"A comparative assessment of CD4 recovery in a cohort of patients on different HAART regimens in a Nigerian tertiary healthcare facility","authors":"P. Onah, C. Idoko, Aliyu Kai'gama, Siyaka Abdulateef","doi":"10.4314/ahs.v24i2.3","DOIUrl":"https://doi.org/10.4314/ahs.v24i2.3","url":null,"abstract":"Background: Antiretroviral therapy is expected to produce sustained viral load reduction and a rise in CD4 cell count, both of which are important clinical markers of immune recovery. There is contrasting clinical evidence of CD4 stability among patients on long term therapy, which is a major challenge in poor resource settings. This study aims to evaluate CD4 cell recovery among patients on four regimens who have been on long term antiretroviral therapy \u0000Methods: This was a retrospective cohort study using data from the medical records of patients on four antiretroviral regimens. A three year record of CD4 cell count of 405 randomly selected subjects was extracted for analysis. \u0000Results: The increase of CD4 cells was between 65.6 – 82.1% of baseline values, with the highest rise occurring with Efavirenz based regimens. Among patients who achieved target CD4 cell counts ≥ 500 cells/ml, there was further increase of between 22.2 – 34.1% compared to baseline values. The percentage of patients with incomplete immune recovery still remain high among patients on the four regimens 65.9 – 77.8%. \u0000Conclusion: Immune reconstitution continue to occur among patients, however a significant proportion of patients fail to achieve and sustain target CD4 target on the long term. \u0000Keywords: CD4 recovery; different HAART regimens; Nigerian tertiary healthcare facility.","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"78 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141834608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Trends, causes and outcomes of Acute Kidney Injury (AKI) among children attending University of Nigeria Teaching Hospital, Ituku-Ozalla Enugu 埃努古伊图库-奥扎拉尼日利亚大学教学医院儿童急性肾损伤（AKI）的趋势、原因和结果

African health sciences Pub Date : 2024-07-11 DOI: 10.4314/ahs.v24i2.43

Henrietta U Okafor, N. Mbanefo, Vivian N Muoneke, Israel O Odetunde, Samuel N Uwaezuoke, Grace Agu, Edmund N Ossai, Josephat M Chinawa

{"title":"Trends, causes and outcomes of Acute Kidney Injury (AKI) among children attending University of Nigeria Teaching Hospital, Ituku-Ozalla Enugu","authors":"Henrietta U Okafor, N. Mbanefo, Vivian N Muoneke, Israel O Odetunde, Samuel N Uwaezuoke, Grace Agu, Edmund N Ossai, Josephat M Chinawa","doi":"10.4314/ahs.v24i2.43","DOIUrl":"https://doi.org/10.4314/ahs.v24i2.43","url":null,"abstract":"Background: Acute Kidney Injury (AKI) in children is increasingly being recognized as a major problem in resource poor countries like Nigeria. In our own setting where resources for renal replacement therapy are limited, it becomes expedient to identify the cases early, ascertain the common causes and challenges in management. This will inform early interventions and strategies for prevention. \u0000Objectives: This study sought to describe the trends,causes and outcomes in the management of AKI among children attending pediatric nephrology unit of the University of Nigeria Teaching Hospital. \u0000Methods: A retrospective cross- sectional study whereby case folder of children with discharge diagnosis of AKI seen in the pediatric nephrology unit of the University of Nigeria Teaching Hospital in Southeast Nigeria. \u0000Results: 51 case folders fulfilled the inclusion criteria. The age range was 0.8-16 with a mean of 5.3±4.6. There was male predominance with M:F ratio of 2.2:1.The commonest presenting feature was fever (78.4%). Majority (82.9%) came in with greater than and equal to stage 2 AKI (KDIGO) , with mean creatinine value of 494.6±367.44 μmmol. Sepsis and malaria were common associated diagnoses. Eight patients (11.8%) were dialyzed and mortality was 3.9%. \u0000Conclusion: Febrile illnesses such as malaria and sepsis are the commonest cause of AKI in this study and this occurs between the ages of 1 and 9 years. Few of these children with AKI benefited form dialysis. Mortality is low and outcome in this study seems good \u0000Keywords: Children; AKI; renal replacement therapy; prevention.","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"58 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141834637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Predictors of medical cost and Length of stay of motorcycle injury patients presenting to hospitals in Kisumu City, Kenya 在肯尼亚基苏木市医院就诊的摩托车伤患者医疗费用和住院时间的预测因素

African health sciences Pub Date : 2024-07-11 DOI: 10.4314/ahs.v24i2.41

Wilberforce Cholo, W. Odero, Japheths Ogendi

{"title":"Predictors of medical cost and Length of stay of motorcycle injury patients presenting to hospitals in Kisumu City, Kenya","authors":"Wilberforce Cholo, W. Odero, Japheths Ogendi","doi":"10.4314/ahs.v24i2.41","DOIUrl":"https://doi.org/10.4314/ahs.v24i2.41","url":null,"abstract":"Background: Motorcycle crash injuries (MCIs) cause mortality and exert financial cost, globally. However, there is paucity of information on cost and length of stay of motorcycle injuries. \u0000Objective: To assess factors influencing medical costs and length of stay (LOS) of motorcycle crash injuries presenting in hospitals in Kisumu city, \u0000Methods: This was a cross-sectional study in which all 1073 motorcycle injury cases were enrolled over a period of six months. A pre-tested, questionnaire was used to collect data. Data were analysed using Analysis of Variance (ANOVA), logistic regression and multivariable regression analysis. P-value < 0.05 considered significant. \u0000Results: A total of 1073 motorcycle injury visits were made to the hospitals during the study period of which 46.0% were admitted. The total medical cost for motorcycle injury patients was Kshs. 19, 134,877 (USD 191348.77). The mean LOS was 19.8 days (1-235 days). Injuries requiring surgical intervention, higher injury severity score, and helmet non-use were significantly associated with higher medical cost and length of stay. \u0000Conclusion: Motorcycle injuries are a major cause of hospital use and present significant economic burden. Surgical intervention, injury severity and non-helmet use were the major predictors of length of stay and medical costs. \u0000Keywords: Motorcycle injuries; length of stay; cost; predictors; severity.","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"14 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141834677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The impact of introducing The impact of introducing diagnostic and therapeutic upper endoscopy in an ambulatory Surgery Center in Rural Eastern Uganda diagnostic and therapeutic upper endoscopy in an ambulatory Surgery Center in Rural Eastern Uganda 在乌干达东部农村地区一家门诊外科中心引入上内窥镜诊断和治疗技术的影响在乌干达东部农村地区一家门诊外科中心引入上内窥镜诊断和治疗技术的影响

African health sciences Pub Date : 2024-07-11 DOI: 10.4314/ahs.v24i2.44

Marnie Abeshouse Marnie Abeshouse, Linda P Zhang, Callie Horn, Allen T Yu, Moses Binoga Bakaleke, Angellica Giibwa, Daniel Haik B, Michael L Marin, Jerome D Waye, Joseph Okello Damoi

{"title":"The impact of introducing The impact of introducing diagnostic and therapeutic upper endoscopy in an ambulatory Surgery Center in Rural Eastern Uganda diagnostic and therapeutic upper endoscopy in an ambulatory Surgery Center in Rural Eastern Uganda","authors":"Marnie Abeshouse Marnie Abeshouse, Linda P Zhang, Callie Horn, Allen T Yu, Moses Binoga Bakaleke, Angellica Giibwa, Daniel Haik B, Michael L Marin, Jerome D Waye, Joseph Okello Damoi","doi":"10.4314/ahs.v24i2.44","DOIUrl":"https://doi.org/10.4314/ahs.v24i2.44","url":null,"abstract":"Background: The availability of upper endoscopy (UE) is limited in many rural low- and middle-income countries (LMIC). Few studies have evaluated use of elective endoscopies to address esophago-gastric diseases in remote Eastern Uganda. \u0000Objective: This research assesses the impact of introducing UE on diagnosing gastrointestinal diseases endemic to the area. \u0000Methods: This is a retrospective, cross sectional, single center study evaluating patients who received elective UE from Kyabirwa Surgical Center in rural Eastern Uganda, between 2020 to 2022. Primary outcome variables were presenting symptoms, endoscopic diagnoses and respective treatments. \u0000Results: 350 endoscopies were performed for 333 patients, (1:1 male-to-female ratio, average age 48). Abnormalities were found on endoscopy in 73% of patients, revealing diagnoses of esophageal cancer (16.4%, N=64), gastritis (16.7%, N=65), hiatal hernia (8.7%, N=34), esophagitis (7.4%, N=29), ulcer (6.2%, N=24), and candidiasis (5.1%, N=20). Most patients presented with epigastric pain alone (40%, N=133) or dysphagia (39%, N=130). 51% of patients with dysphagia had esophageal cancer on endoscopy, of which 28.1% had an interval palliative stent placed. \u0000Conclusions: The introduction of UE into a rural LMICs is possible and can verify baseline prevalence of endemic upper gastrointestinal diseases. Confirmation of diagnosis by endoscopy can direct medical management and interventional therapy. \u0000Keywords: Diagnostic and therapeutic upper endoscopy; ambulatory surgery center; rural Eastern Uganda.","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"108 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141834991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adverse effects associated with Kanamycin, Amikacin, Capreomycin and Bedaquiline -a VigiAccessTM study 与卡那霉素、阿米卡星、卡普霉素和贝达喹啉有关的不良反应 - VigiAccessTM 研究

African health sciences Pub Date : 2024-07-11 DOI: 10.4314/ahs.v24i2.8

Lisa Singh, Varsha Bangalee, Serisha Ramasir, Lehlohonolo John Mathibe

{"title":"Adverse effects associated with Kanamycin, Amikacin, Capreomycin and Bedaquiline -a VigiAccessTM study","authors":"Lisa Singh, Varsha Bangalee, Serisha Ramasir, Lehlohonolo John Mathibe","doi":"10.4314/ahs.v24i2.8","DOIUrl":"https://doi.org/10.4314/ahs.v24i2.8","url":null,"abstract":"Background: Multidrug-resistant tuberculosis (MDR-TB) is a prevalent health burden, both in South Africa and globally. The treatment of MDR-TB is both complex and difficult as multiple drugs have to be used concurrently in order to achieve good treatment outcomes for patients. However, there is a lack in the evidence regarding the incidences of specific adverse effects of these drugs. \u0000Objective: The main aim/objective of this study was to investigate and compare reported specific adverse drug reactions (ADRs) associated with kanamycin, capreomycin, amikacin and bedaquiline in MDR-TB patients. \u0000Methods: Secondary data collected over a period of 12 months were sourced from a public access data base, VigiAccessTM, and analysed. \u0000Results: There was a steep increase in adverse drug reactions reported for kanamycin with the main adverse reactions being hypoacusis, deafness and tinnitus cases, along with vomiting, nausea and diarrhoea. With capreomycin, there were increases in asthenia and hypoacusis although the latter showed a plateau after some point. Rash and pruritus increased along with cases of death with amikacin and there were reports of prolonged QT interval in the electrocardiogram of patients on bedaquiline in addition to nausea, vomiting and diarrhoea. \u0000Conclusion: There are many specific adverse effects associated with kanamycin, capreomycin, amikacin and bedaquiline. The number of cases of the specific adverse effects also increased with time. Therefore, VigiAccessTM provides a good platform for reporting and awareness of specific adverse effects associated with MDR-TB therapy. This is a vital stepping stone for further research. \u0000Keywords: Kanamycin; Amikacin; Capreomycin; Bedaquiline.","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"127 s443","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141835039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0