Aris P Agouridis, Theodosios D Filippatos, Christina Kostara, Vasilis Tsimihodimos, Michalis S Kostapanos
{"title":"The Effect of Low, Moderate, and High Doses of Rosuvastatin on Lipoprotein(a) Levels in Hyperlipidemic Patients with Impaired Fasting Glucose: A Post-Hoc Analysis.","authors":"Aris P Agouridis, Theodosios D Filippatos, Christina Kostara, Vasilis Tsimihodimos, Michalis S Kostapanos","doi":"10.5543/tkda.2024.37794","DOIUrl":"https://doi.org/10.5543/tkda.2024.37794","url":null,"abstract":"","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":"53 2","pages":"155-156"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143545319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Taha Okan, Caner Topaloğlu, Cihan Altın, Mehmet Doruk, Mehmet Birhan Yılmaz
{"title":"Pentraxin 3: A Marker for the Presence and Severity of Coronary Artery Disease.","authors":"Taha Okan, Caner Topaloğlu, Cihan Altın, Mehmet Doruk, Mehmet Birhan Yılmaz","doi":"10.5543/tkda.2024.76839","DOIUrl":"10.5543/tkda.2024.76839","url":null,"abstract":"<p><strong>Objective: </strong>Atherosclerosis, a major contributor to coronary artery disease (CAD), is characterized by chronic arterial inflammation. Pentraxin 3 (PTX-3), a biomarker of inflammation, serves as an indicator of both atherosclerosis and the progression of CAD. The aim of this study was to investigate the association between PTX-3 levels and the presence and severity of CAD, as determined by coronary computed tomography angiography (CCTA).</p><p><strong>Method: </strong>In this study, 94 participants (54 with CAD and 40 controls) underwent CCTA and coronary artery calcium scoring (CACS) using computed tomography. PTX-3 levels were measured using the enzyme-linked immunosorbent assay (ELISA) method. CAD patients were categorized based on CCTA findings and further subdivided into three groups according to their CACS: Group I (CACS < 100), Group II (CACS 100-299), and Group III (CACS ≥ 300).</p><p><strong>Results: </strong>Serum PTX-3 levels were significantly higher in the CAD group. A PTX3 cut-off value of 5.80 ng/mL predicted CAD with 68% sensitivity and 66% specificity. A strong positive correlation was observed between CACS and PTX-3 levels (r = 0.521, P < 0.001). In high-risk patients with a CACS ≥ 300, PTX-3 levels were significantly higher than those in low- and intermediate-risk groups a CACS < 300. However, no significant difference in PTX-3 levels was observed between the normal coronary group and the low- and intermediate-risk groups. Furthermore, no correlation was found between the degree of coronary artery stenosis and PTX-3 levels.</p><p><strong>Conclusion: </strong>Pentraxin 3 might serve as a valuable biomarker for the diagnosis and severity of CAD.</p>","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":"53 2","pages":"87-92"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143545268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Symptomatic Severe Bradycardia during Pazopanib Treatment.","authors":"Cafer Zorkun, Öykü Alara Eren","doi":"10.5543/tkda.2024.03788","DOIUrl":"10.5543/tkda.2024.03788","url":null,"abstract":"<p><p>Pazopanib, a tyrosine kinase inhibitor that targets growth factor receptors, is associated with various side effects, including bradycardia. We report a severe case of symptomatic bradycardia, with a heart rate dropping to 28 beats per minute, in a patient with cardiac angiosarcoma treated with 800 mg/day of pazopanib. Reducing the dosage to 600 mg/day improved the heart rate to 53 beats per minute. This case highlights the risk of severe bradycardia associated with pazopanib, emphasizing the need for vigilant heart rate monitoring.</p>","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":"53 2","pages":"140-142"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143545313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mehmet Özyaşar, Mustafa Doğduş, Ahmet Yılmaz, Mehmet Sait Altıntaş, Ertan Yetkin
{"title":"Reply to the Letter to the Editor: 'Coronary Atherosclerosis Burden and Coronary Artery Tortuosity'.","authors":"Mehmet Özyaşar, Mustafa Doğduş, Ahmet Yılmaz, Mehmet Sait Altıntaş, Ertan Yetkin","doi":"10.5543/tkda.2025.92377","DOIUrl":"https://doi.org/10.5543/tkda.2025.92377","url":null,"abstract":"","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":"53 2","pages":"154"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143545283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hülya Yılmaz Ak, Mustafa Yıldız, Ahmet Yıldız, Sait Mesut Doğan, Ziya Salihoğlu, Kerem Erkalp, Emir Özgür Barış Ökçün, Yasemin Özşahin
{"title":"Adaptation of the Enhanced Recovery After Surgery (ERAS®) Protocol in Transcatheter Aortic Valve Replacement Patients.","authors":"Hülya Yılmaz Ak, Mustafa Yıldız, Ahmet Yıldız, Sait Mesut Doğan, Ziya Salihoğlu, Kerem Erkalp, Emir Özgür Barış Ökçün, Yasemin Özşahin","doi":"10.5543/tkda.2024.98566","DOIUrl":"10.5543/tkda.2024.98566","url":null,"abstract":"<p><p>Enhanced Recovery After Surgery (ERAS®) is a multimodal, multidisciplinary care and recovery protocol designed to facilitate faster recovery for patients undergoing surgery during the perioperative period. These programs aim to encourage an earlier return to normal activities by reducing complications. While ERAS® protocols have become standard practice in many surgical specialties, their application in the transcatheter aortic valve replacement (TAVI) procedure is relatively recent. TAVI patients are often high-risk and medically fragile. We believe that managing these patients with a multidisciplinary approach, such as the ERAS® protocol, during the preoperative and postoperative periods will reduce morbidity and mortality, enhance patient satisfaction, and lower hospital costs.</p>","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":"53 2","pages":"127-133"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143545257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Spyridon-Filippos Papadopoulos, Emmanouela Peteinidou, Konstantinos C Theodoropoulos, Matthaios Didagelos, Athanasios Samaras, Aristi Boulmpou, Thomas Gossios, Antonios Kouparanis, George Kassimis, Antonios Ziakas
{"title":"Cangrelor Monotherapy Bridging for Cardiac and Non-Cardiac Surgery Following Percutaneous Coronary Intervention.","authors":"Spyridon-Filippos Papadopoulos, Emmanouela Peteinidou, Konstantinos C Theodoropoulos, Matthaios Didagelos, Athanasios Samaras, Aristi Boulmpou, Thomas Gossios, Antonios Kouparanis, George Kassimis, Antonios Ziakas","doi":"10.5543/tkda.2024.86987","DOIUrl":"10.5543/tkda.2024.86987","url":null,"abstract":"<p><p>Managing dual antiplatelet therapy (DAPT) perioperatively is challenging, especially in patients who have recently undergone percutaneous coronary intervention (PCI). Intravenous antiplatelet agents are recommended in these cases. This case series describes the perioperative management of two high bleeding risk patients with recent PCI undergoing cardiac and non-cardiac surgeries using cangrelor monotherapy.</p>","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":"53 2","pages":"143-147"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143545238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Percutaneous Extraction of Catheter Trapped in the Right Ventricle.","authors":"Ramin Eskandari, Yousef Rezaei","doi":"10.5543/tkda.2024.29608","DOIUrl":"10.5543/tkda.2024.29608","url":null,"abstract":"","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":"53 2","pages":"152"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143545275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aykut Demirkıran, Cihan Aydın, Aydın Akyüz, Şeref Alpsoy
{"title":"Ten-Year Outcomes Following Revascularization Strategies for Non-ST-Segment Elevation Myocardial Infarction and Multivessel Disease.","authors":"Aykut Demirkıran, Cihan Aydın, Aydın Akyüz, Şeref Alpsoy","doi":"10.5543/tkda.2024.59839","DOIUrl":"10.5543/tkda.2024.59839","url":null,"abstract":"<p><strong>Objective: </strong>There remain conflicting recommendations regarding revascularization strategies for patients with non-ST-segment elevation myocardial infarction (NSTEMI) and multivessel disease (MVD). This study aimed to compare the long-term outcomes of different revascularization strategies.</p><p><strong>Method: </strong>Patients with similar characteristics were categorized into three groups: immediate complete revascularization (ICR), staged complete revascularization (SCR), and non-complete revascularization (NCR). The SCR group was further divided based on the time interval between the index and staged procedures: SCR ≤ 24 hours and SCR > 24 hours. Cardiac composite outcomes included the total number of cardiac deaths and recurrent myocardial infarction during the follow-up period.</p><p><strong>Results: </strong>Out of 14,511 screened patients, 316 were included in the analysis. The results showed a significant difference in risk between SCR and ICR (hazard ratio [HR] (95% confidence interval [CI]): 0.27 (0.15-0.47); P = 0.001). There was no significant difference between NCR and SCR (HR (95% CI): 1.06 (0.61-1.84); P = 0.832). The SCR group was divided into two groups based on the time interval from the first to the second procedure (time interval [TI] ≤ 24 hours in the SCR1 group, and TI > 24 hours in the SCR2 group). The frequency of cardiac composite outcomes was lower in SCR1 compared to SCR2 (16.7% vs. 47.1%; P = 0.038).</p><p><strong>Conclusion: </strong>Our findings support the use of ICR and SCR completed within 24 hours due to their favorable long-term outcomes in patients with MVD and NSTEMI.</p>","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":"53 2","pages":"93-99"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143545316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emir Baskovski, İrem Cenan Büyükçakır, Timuçin Altın, Ömer Akyürek
{"title":"Utilization of Coronary Venous Ethanol Ablation for Intramural Ventricular Arrhythmias in Two Different Scenarios: A How-To Approach.","authors":"Emir Baskovski, İrem Cenan Büyükçakır, Timuçin Altın, Ömer Akyürek","doi":"10.5543/tkda.2024.21859","DOIUrl":"10.5543/tkda.2024.21859","url":null,"abstract":"<p><p>Catheter-based radiofrequency (RF) ablation is a recommended treatment modality for various ventricular arrhythmias. However, challenging sites that may not be accessible due to anatomical reasons, as well as intramural sites, where RF energy penetration may be limited, pose challenges that limit the success rate of RF ablation. Ethanol ablation may be an alternative option for treatment of ventricular arrhythmias that are not amenable to treatment by RF ablation. This report describes two cases of successful venous alcohol ablation for refractory ventricular tachycardia to standard RF ablation procedure. In the first case, a patient with a ventricular tachycardia (VT) originating from intramural outflow tract, having failed an endocardial ablation, underwent a successful ethanol ablation, via a double balloon technique. In the second case, we describe a patient with a history of transcatheter aortic valve replacement and premature ventricular complexes (PVCs) originating from intramural outflow tract. Radiofrequency ablation in this patient was limited by both the far-field appearing signals and the proximity prosthetic valve to the site of these signals. Therefore, this patient also underwent successful ethanol ablation of annular vein with the over the wire system after venography of coronary sinus. No complications were observed in both patients. In conclusion, coronary venous ethanol ablation may be a safe and successful technique for ablation of intramural ventricular arrhythmias in different clinical scenarios.</p>","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":"53 2","pages":"134-139"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143545485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}