Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir最新文献

{"title":"Effect of Sacubitril/Valsartan and Dapagliflozin on Cardiac Functions and Exercise Capacity of Rats.","authors":"Akın Torun, Şahhan Kılıç, Süha Asal, Mert Babaoğlu, Samet Yavuz, Cumaali Demirtaş, Serkan Dilmen, Ahmet Lutfullah Orhan, Mehmet Uzun","doi":"10.5543/tkda.2024.74353","DOIUrl":"10.5543/tkda.2024.74353","url":null,"abstract":"<p><strong>Objective: </strong>Recent studies have demonstrated the positive effects of sacubitril/valsartan and dapagliflozin on cardiac prognosis and performance. These drugs have the potential to be misused as doping agents by professional athletes. This study aimed to evaluate the effects of sacubitril/valsartan and dapagliflozin on athletic performance.</p><p><strong>Methods: </strong>In this study, swimming performance was assessed in three groups of rats divided into control, sacubitril/valsartan, and dapagliflozin groups. Echocardiography, weight, and rotarod performance were also evaluated during follow-up.</p><p><strong>Results: </strong>In comparisons between the sacubitril/valsartan and control groups, a statistical difference was observed in the 13th, 19th, and 20th swimming sessions. For total and median swimming times, the P values were 0.115 and 0.015, respectively. In comparisons between the dapagliflozin and control groups, a statistical difference was observed starting from the 10th swimming session, with P values of < 0.001 for both total and median swimming times. In a three-group analysis, statistical differences were observed from the ninth swimming session until the end of the experiment. Additionally, rotarod results showed a significant difference for both sacubitril/valsartan and dapagliflozin compared to baseline (P < 0.001 and P = 0.011, respectively).</p><p><strong>Conclusion: </strong>This study demonstrated a limited positive effect of sacubitril/valsartan on athletic performance, while the impact of dapagliflozin on athletic performance was particularly significant.</p>","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":"53 1","pages":"13-21"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142967639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Percutaneous Mitral Valve-in-Ring Procedure in a Case of Severe Mitral Regurgitation Repaired with a Surgical Flexible Ring: A Step-by-Step Description.","authors":"Hüseyin Bozbaş, Savaş Aksüyek Çelebi, Mohamed Asfour, Basri Amasyalı, Cem Barçın","doi":"10.5543/tkda.2024.41877","DOIUrl":"10.5543/tkda.2024.41877","url":null,"abstract":"<p><p>Severe mitral regurgitation (MR) following surgical repair of the mitral valve poses a significant clinical challenge. Patients who have undergone surgery are typically at high risk for a second operation. This report details the case of a 54-year-old male who underwent aortic valve replacement and mitral valve repair using a 34-ring, 14 years prior. The patient presented with severe MR, severe left ventricular (LV) dilation, and a reduced ejection fraction of 20%. A Sovering 34 ring, characterized by its oval, radio-opaque, and flexible nature and completely encircling the annulus, was used. After comprehensive assessment utilizing cardiac computed tomography (CT) and the Valve-in-Valve (ViV) application, a 32 mm balloon-expandable transcatheter heart valve was chosen. The selected valve was the 32 mm Myval (Meril) valve, the largest size available globally. Following careful alignment (left atrium/left ventricle ratio (LA/LV) ratio 20/80) and under rapid pacing, the valve was successfully implanted within the ring. Subsequent transesophageal echocardiography confirmed the valve's functionality, and left ventriculography showed no paravalvular regurgitation. The Mitral Valve-in-Ring (MVIR) procedure emerges as a promising therapeutic option for patients with a history of mitral valve repair and severe MR. This procedure is preferred in centers where structural heart interventions are performed by an experienced team.</p>","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":"53 1","pages":"68-72"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142967643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Evaluation of Chatbot Responses on Coronary Artery Disease.","authors":"Levent Pay, Ahmet Çağdaş Yumurtaş, Tuğba Çetin, Tufan Çınar, Mert İlker Hayıroğlu","doi":"10.5543/tkda.2024.78131","DOIUrl":"10.5543/tkda.2024.78131","url":null,"abstract":"<p><strong>Objective: </strong>Coronary artery disease (CAD) is the leading cause of morbidity and mortality globally. The growing interest in natural language processing chatbots (NLPCs) has driven their inevitable widespread adoption in healthcare. The purpose of this study was to evaluate the accuracy and reproducibility of responses provided by NLPCs, such as ChatGPT, Gemini, and Bing, to frequently asked questions about CAD.</p><p><strong>Methods: </strong>Fifty frequently asked questions about CAD were asked twice, with a one-week interval, on ChatGPT, Gemini, and Bing. Two cardiologists independently scored the answers into four categories: comprehensive/correct (1), incomplete/partially correct (2), a mix of accurate and inaccurate/misleading (3), and completely inaccurate/irrelevant (4). The accuracy and reproducibility of each NLPC's responses were assessed.</p><p><strong>Results: </strong>ChatGPT's responses were scored as 14% incomplete/partially correct and 86% comprehensive/correct. In contrast, Gemini provided 68% comprehensive/correct responses, 30% incomplete/partially correct responses, and 2% a mix of accurate and inaccurate/misleading information. Bing delivered 60% comprehensive/correct responses, 26% incomplete/partially correct responses, and 8% a mix of accurate and inaccurate/misleading information. Reproducibility scores were 88% for ChatGPT, 84% for Gemini, and 70% for Bing.</p><p><strong>Conclusion: </strong>ChatGPT demonstrates significant potential to improve patient education about coronary artery disease by providing more sensitive and accurate answers compared to Bing and Gemini.</p>","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":"53 1","pages":"35-43"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142967638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recovery of Myocardial Functions After Kidney Transplantation in Patients with Heart Failure Due to Uremic Cardiomyopathy.","authors":"Yelda Saltan Özateş, Ahmet Yener Odabaşı, Ufuk Yıldız, Duygu Genç Albayrak, Duygu İnan, Serap Baş, Asiye Işın Doğan Ekici, Mehmet Emin Demir, Ahmet İlker Tekkeşin","doi":"10.5543/tkda.2024.93263","DOIUrl":"10.5543/tkda.2024.93263","url":null,"abstract":"<p><strong>Objective: </strong>Although left ventricular hypertrophy frequently accompanies end-stage renal disease, heart failure (HF) with reduced ejection fraction (EF) is also observed in a subset of patients. In those patients kidney transplantation (KT) is generally avoided due to an increased risk of mortality in addition to the risks associated with HF. This prospective study was designed to follow patients with HF who were being prepared for KT.</p><p><strong>Methods: </strong>Twenty-five patients with HF due to uremic cardiomyopathy (UC) who had suitable donors (Group 1), 22 patients with HF who could not undergo KT due to a lack of kidney donors (Group 3), and 25 KT candidates with normal ventricular function (Group 2) were included in the study. Left ventricular ejection fraction (LVEF), left atrial diameter (LAD), mitral annular systolic velocity (Sm), left ventricular global longitudinal strain (GLS), and left ventricular mass index (LVMI) values were recorded across four sessions, from pre-transplant to six months post-transplantation. Endomyocardial biopsy was performed for detailed examination of the myocardium in patients in Group 1 and Group 3, and cardiac magnetic resonance imaging (MRI) was performed in all three groups before transplantation.</p><p><strong>Results: </strong>In Group 1, LVEF, Sm, and left ventricular global longitudinal strain (LV-GLS) increased significantly, while LAD and LVMI decreased, all reaching normal levels. In contrast, no changes were observed in Group 3 and Group 2 (P < 0.01 for LVEF, P < 0.01 for GLS, P < 0.01 for LAD, and P < 0.01 for LVMI measurements). No differences in cardiac MRI and biopsy findings were observed between Group 1 and Group 3.</p><p><strong>Conclusion: </strong>Since myocardial function improved significantly and normalized in all patients with HF, it has been demonstrated that UC can be substantially reversible when treated with KT.</p>","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":"53 1","pages":"1-12"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142967644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply to the Letter to the Editor: ''The Need for a New Description of Red Flags in Cardiac Amyloidosis in Turkish Population''.","authors":"Selda Murat, Halit Emre Yalvaç, Yüksel Çavuşoğlu","doi":"10.5543/tkda.2024.84415","DOIUrl":"https://doi.org/10.5543/tkda.2024.84415","url":null,"abstract":"","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":"53 1","pages":"82-83"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142967646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful Intravascular Ultrasound-Guided Shockwave Intravascular Lithotripsy for a Severely Calcified and Resistant Proximal Left Anterior Descending Coronary Artery Lesion in a Patient with ST-Segment Elevation Myocardial Infarction.","authors":"George Kassimis, Konstantinos C Theodoropoulos, Matthaios Didagelos, Antonios Ziakas, Nikolaos Fragakis","doi":"10.5543/tkda.2024.10248","DOIUrl":"https://doi.org/10.5543/tkda.2024.10248","url":null,"abstract":"","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":"53 1","pages":"75-76"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142967647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Need for a New Description of Red Flags in Cardiac Amyloidosis in Turkish Population.","authors":"İrem Yılmaz, Mustafa Oğuz, Almina Erdem, Mert Babaoğlu, Mehmet Uzun","doi":"10.5543/tkda.2024.14042","DOIUrl":"https://doi.org/10.5543/tkda.2024.14042","url":null,"abstract":"","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":"53 1","pages":"80-81"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142967648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Rare Complication of Temporary Pacemaker Lead Dislodgment: Iatrogenic Twitching of the Left Lower Extremity.","authors":"Abdulrahman Naser, Yücel Uzun, Oya Güven","doi":"10.5543/tkda.2023.50774","DOIUrl":"https://doi.org/10.5543/tkda.2023.50774","url":null,"abstract":"","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":"53 1","pages":"73-74"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142967688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hypereosinophilic Syndrome Complicated by Eosinophilic Myocarditis: Embolic Stroke or Eosinophilic Stroke? A Case Report.","authors":"Amirreza Sajjadieh Khajouei, Marzieh Tajmirriahi, Zahra Payandeh, Mahsa Amirhajlou Mashhadi, Nahid Shirani, Seyedeh Mahnaz Mirbod","doi":"10.5543/tkda.2024.46487","DOIUrl":"10.5543/tkda.2024.46487","url":null,"abstract":"<p><p>Hypereosinophilic syndrome (HES) is traditionally described as chronic peripheral eosinophilia with involvement of various organs and systems, including the heart and nervous system. In this report, we describe cardiac involvement and border zone stroke in a patient with idiopathic HES. A 37-year-old woman presented with sudden right-sided weakness and slurred speech, which began four days before admission, accompanied by palpitations, retrosternal exertional chest discomfort, dry cough, and progressive shortness of breath over approximately two months. Preliminary studies showed an increased number of white blood cells with eosinophilia. Further diagnostic investigation revealed apical thrombosis in both ventricles of the heart and moderate left ventricular systolic dysfunction. Magnetic resonance imaging of the brain indicated multifocal infarctions in the anterior and posterior border zones, as well as both cerebellar hemispheres, predominantly on the left side. Consequently, the patient was diagnosed with idiopathic HES and treated with corticosteroids, cyclophosphamide, anticoagulants, and medications for heart failure. She responded well both clinically and hematologically. Our case highlights the importance of multiple imaging modalities in diagnosing eosinophilic endomyocarditis and the impact of timely medical treatment to prevent disease progression.</p>","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":"53 1","pages":"62-67"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142967640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"News and Comments from Cardiology.","authors":"Ertan Ural","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":"53 1","pages":"84-85"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142967642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}