{"title":"Development of In-Hospital and Discharge Protocols for Optimal Lipid-Lowering Strategies in Patients with Acute Coronary Syndrome in Türkiye: Expert Guidance.","authors":"Öner Özdoğan, Meral Kayıkçıoğlu, Barış Güngör, Ceyhun Ceyhan, Özcan Başaran, Mithat Selvi, Lale Tokgözoğlu","doi":"10.5543/tkda.2024.68708","DOIUrl":"https://doi.org/10.5543/tkda.2024.68708","url":null,"abstract":"<p><p>Although guidelines strongly recommend low levels of low-density lipoprotein cholesterol (LDL-C) in patients with acute coronary syndrome (ACS), these goals are not achieved in many patients. We present expert recommendations for the in-hospital and post-discharge management of lipid-lowering therapy in ACS patients in Türkiye. A group of expert cardiologists comprising members of the Turkish Society of Cardiology and leading lipidologists who have all worked in national cardiology lipid working groups for at least 4 years, considered the optimal approach to lipid management in ACS patients in Türkiye, taking into account Turkish healthcare infrastructure and issues from real-world practice. Novel standardized algorithms covering the first year after an ACS event were developed. The main elements of the proposed approach are summarized. The in-hospital strategy includes lipid profile assessments and commencement of statin therapy, including appropriate measures for patients with possible familial hypercholesterolemia or with a history of recurrent cardiovascular events. The role of a specially-trained nurse, use of a patient follow-up card, and the provision of patient information and referrals to affiliated healthcare professionals, are covered. The post-discharge strategy covers follow-up visits to monitor the patient's progress and recommends timepoints at which modifications to treatment (based on LDL-C levels) should be made. A country-specific approach to lipid management in ACS patients in Türkiye is proposed. Further work is needed to determine the best way to implement the strategy, and to validate the recommendations and their application in daily practice.</p>","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":"52 8","pages":"590-599"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142776145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emine Hekim Yılmaz, Nurgül Yurtseven, Oktay Korun, Murat Çiçek, Hüseyin Karadağ, Murat Sürücü, İbrahim Halil Demir, Numan Ali Aydemir, Ahmet Çelebi
{"title":"Junctional Ectopic Tachycardia After Congenital Heart Surgery: Incidence, Risk Factors, and Outcomes.","authors":"Emine Hekim Yılmaz, Nurgül Yurtseven, Oktay Korun, Murat Çiçek, Hüseyin Karadağ, Murat Sürücü, İbrahim Halil Demir, Numan Ali Aydemir, Ahmet Çelebi","doi":"10.5543/tkda.2024.77449","DOIUrl":"https://doi.org/10.5543/tkda.2024.77449","url":null,"abstract":"<p><strong>Objective: </strong>Postoperative junctional ectopic tachycardia (JET) is usually a self-limiting condition; however, when combined with atrioventricular dissociation and postoperative ventricular dysfunction, it may increase morbidity and mortality. This study aimed to determine the overall incidence of JET following congenital heart surgery, to identify patient and procedure-related risk factors, and to evaluate the clinical impact of JET on outcomes.</p><p><strong>Methods: </strong>The records of 2,814 patients who underwent cardiac surgery over a five-year period were reviewed retrospectively to identify those with JET. For each patient diagnosed with JET, two controls who underwent surgery during the same period were selected to compare possible risk factors and outcomes.</p><p><strong>Results: </strong>The incidence of JET following congenital heart surgery was 2.66% in this large cohort. Univariate analyses revealed statistically significant associations between JET and factors such as young age, small body weight, high vasoactive inotropic score, operations involving the ventricular septum, surgical complexity score, increased cardiopulmonary bypass time, delayed sternal closure, extracorporeal membrane oxygenation (ECMO) requirement, and increased risk of postoperative JET. In multivariate analysis only the association between surgeries involving the ventricular septum, ECMO requirement, and increased risk of JET persisted. Compared to controls, patients with JET experienced prolonged intubation times, longer stays in the intensive care unit and hospital, more frequent unplanned re-interventions, and higher mortality rates.</p><p><strong>Conclusion: </strong>Junctional ectopic tachycardia can lead to serious hemodynamic consequences in patients following congenital heart surgery and is associated with poorer clinical outcomes. Both patient and procedure-related factors contribute to the overall risk of developing JET. Identifying associations and predictors of JET can help improve patient outcomes.</p>","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":"52 8","pages":"567-573"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142776157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Özer Badak, Demet Özkaramanlı Gür, Çağlar Kaya, Tugay Önal, Onur Saydam, İbrahim Faruk Aktürk, Servet Altay, Ahmet Altuğ Çinçin, Refik Emre Altekin, Göksel Çağırcı, Kadriye Kılıçkesmez, Veli Polat, Dursun Aras
{"title":"Assessment of Non-Vitamin K Antagonist Oral Anticoagulant Dosing Patterns in Turkish Patients with Non-Valvular Atrial Fibrillation: A Multicenter, Cross-Sectional Study with Insights from the ASPECT-NOAC Study.","authors":"Özer Badak, Demet Özkaramanlı Gür, Çağlar Kaya, Tugay Önal, Onur Saydam, İbrahim Faruk Aktürk, Servet Altay, Ahmet Altuğ Çinçin, Refik Emre Altekin, Göksel Çağırcı, Kadriye Kılıçkesmez, Veli Polat, Dursun Aras","doi":"10.5543/tkda.2024.47718","DOIUrl":"10.5543/tkda.2024.47718","url":null,"abstract":"<p><strong>Objective: </strong>We aimed to assess the real-world label adherence of non-vitamin K antagonist oral anticoagulant (NOAC) dosing patterns, including apixaban, edoxaban, and rivaroxaban, in Turkish patients with atrial fibrillation.</p><p><strong>Methods: </strong>This was an observational, prospective, cross-sectional, multicenter study. Patients with atrial fibrillation (AF) who were prescribed NOACs within the last 4 months were recruited from 34 cardiology clinics in Türkiye. Baseline data were initially collected, and patient awareness was evaluated at 3-4 weeks.</p><p><strong>Results: </strong>A total of 903 patients were enrolled in the study. The mean age was 72.84 ± 10.17 years. We found that 140 (15.5%), 721 (79.8%), and 42 patients (4.7%) were prescribed off-label low, on-label, and off-label high dosing, respectively. The age of the patients in the on-label group was significantly lower than that of those in the off-label low and off-label high groups (both P < 0.001). Female patients were more frequently observed in the off-label high group (P = 0.019). The body mass index values of the patients in the off-label high-dose group were significantly lower than those in the other groups (P < 0.001). The perception of income levels also revealed significant differences between the groups (P = 0.010). Furthermore, the HAS-BLED scores (the Hypertension, Abnormal Renal/Liver Function, Stroke, Bleeding History or Predisposition, Labile International Normalized Ratio, Elderly, Drugs/Alcohol Concomitantly) were significantly lower in the on-label group than in the other groups (P < 0.001). Similarly, the CHA2DS2-VASc [the Congestive Heart Failure, Hypertension, Age ≥75 (Doubled), Diabetes, Stroke (Doubled), Vascular Disease, Age 65-74, and Sex Category (Female)] scores were significantly lower in the on-label group than in the off-label group (P < 0.001).</p><p><strong>Conclusion: </strong>The clinical impact off-label NOAC prescriptions may vary. Therefore, raising clinician awareness about proper NOAC dosing could aid in improve the outcomes.</p>","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":"52 8","pages":"574-580"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142776126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Reşit Yiğit Yılancıoglu, Oğuzhan Ekrem Turan, Hatice Özdamar, Hüseyin Dursun, Emin Evren Özcan, Dayimi Kaya
{"title":"Invasive Management of Iatrogenic Left Internal Mammary Artery-Great Cardiac Vein Anastomosis: A Case Report.","authors":"Reşit Yiğit Yılancıoglu, Oğuzhan Ekrem Turan, Hatice Özdamar, Hüseyin Dursun, Emin Evren Özcan, Dayimi Kaya","doi":"10.5543/tkda.2023.30810","DOIUrl":"https://doi.org/10.5543/tkda.2023.30810","url":null,"abstract":"<p><p>Coronary artery bypass graft (CABG) surgery is one of the main treatment procedures for revascularization. Diagnosing postoperative complications can be difficult. One rare complication is the iatrogenic connection of the graft to the venous system, causing distal ischemia due to an arteriovenous shunt. This condition may lead to heart failure and fatal arrhythmias. Anti-arrhythmic drug-resistant ventricular arrhythmias, which can occur immediately after coronary artery bypass surgery, are sometimes related to the procedure itself. We describe the invasive management of an iatrogenic anastomosis between the left internal mammary artery (LIMA) and the great cardiac vein (GCV), which led to life-threatening ventricular arrhythmias.</p>","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":"52 8","pages":"600-605"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142776154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mehmet Özyaşar, Mustafa Doğduş, Ahmet Yılmaz, Mehmet Sait Altıntaş, Ertan Yetkin
{"title":"Clinical Significance of Coronary Artery Tortuosity in Chronic Coronary Syndrome and Stable Angina: Insights from Gensini Scores.","authors":"Mehmet Özyaşar, Mustafa Doğduş, Ahmet Yılmaz, Mehmet Sait Altıntaş, Ertan Yetkin","doi":"10.5543/tkda.2024.87425","DOIUrl":"https://doi.org/10.5543/tkda.2024.87425","url":null,"abstract":"<p><strong>Objective: </strong>This study investigated the clinical significance of coronary artery tortuosity (CAT) in chronic coronary syndrome (CCS) using Gensini scores.</p><p><strong>Method: </strong>This retrospective single-center study involved 388 patients undergoing coronary angiography for chest pain, excluding those with acute coronary syndromes or prior coronary interventions. Demographic, clinical, and angiographic data were collected and categorized based on the presence or absence of CAT.</p><p><strong>Results: </strong>Analysis of 388 patients revealed that CAT was associated with older age (P < 0.001), female gender (P < 0.001), lower rates of smoking (19.3% vs. 29.6%, P = 0.025), and hypertension (53.5% vs. 38.7%, P = 0.05). There was a slightly higher, nearly significant, prevalence of diabetes in the CAT group (22.8% vs. 14.5%, P = 0.051). Furthermore, CAT correlated with diastolic dysfunction (P = 0.04) and was inversely related to the severity of coronary atherosclerosis, as indicated by lower Gensini scores correlating with higher CAT scores (P = 0.039 and P = 0.049, respectively). Univariate analysis confirmed CAT's association with older age (P < 0.001), female gender (P < 0.001), hypertension (P = 0.004), diabetes (P = 0.039), diastolic dysfunction (P = 0.003), and Gensini score (P = 0.012). Multivariate analysis further identified significant correlations with age (P = 0.001), female gender (P < 0.001), and Gensini score (P = 0.049).</p><p><strong>Conclusion: </strong>Our findings indicate that older age and female gender predict presence of CAT in CCS patients. The lower Gensini scores associated with CAT may possibly be due to a reduced atherosclerotic plaque burden in these patients. Further research into this relationship could inform the development of treatment and management strategies for coronary atherosclerosis.</p>","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":"52 8","pages":"553-560"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142776131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kutluhan Eren Hazır, Kerem Aydın Mutlugüleçler, İrfan Özgen, Burçin Abud, Cenk Sarı
{"title":"Giant Metastatic Intracardiac Malignant Fibrous Tumor Presenting with Supraventricular Tachycardia: A Case Report.","authors":"Kutluhan Eren Hazır, Kerem Aydın Mutlugüleçler, İrfan Özgen, Burçin Abud, Cenk Sarı","doi":"10.5543/tkda.2023.19310","DOIUrl":"https://doi.org/10.5543/tkda.2023.19310","url":null,"abstract":"<p><p>Solitary fibrous tumors (SFTs) are rare neoplasms originating from fibroblastic mesenchymal cells. This case report details a 43-year-old female patient with cardiac SFT, a rarity in the medical literature, who presented with palpitations and a known malignancy. Supraventricular tachycardia was diagnosed in the emergency department, and a subsequent echocardiography revealed a giant mass in the left atrium after sinus rhythm restoration. The mass, causing symptomatic severe mitral stenosis, necessitated surgical intervention. Pathological examination of the surgical specimens confirmed the diagnosis of SFT. Cardiac masses are extremely rare in clinical practice, and the literature on SFTs is primarily limited to case reports. More research is needed due to the scarcity of information on managing this condition.</p>","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":"52 8","pages":"611-614"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142776151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Percutaneous Retrieval of an Atrial Septal Defect Closure Device Embolized to the Abdominal Aorta.","authors":"Çiğdem Deniz, Uğur Canpolat, Kudret Aytemir","doi":"10.5543/tkda.2023.80469","DOIUrl":"https://doi.org/10.5543/tkda.2023.80469","url":null,"abstract":"","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":"52 8","pages":"617-618"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142776163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}