Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir最新文献

{"title":"Pulmonary Arterial Hypertension After Repair of Classical Tetralogy of Fallot.","authors":"Gurajala Venkatesh, Harikrishnan Kurup, Karthik Raghuram, Deepa Sasikumar, Kavassery Mahadevan Krishnamoothy, Arun Gopalakrishnan","doi":"10.5543/tkda.2024.08698","DOIUrl":"10.5543/tkda.2024.08698","url":null,"abstract":"<p><p>Tetralogy of Fallot (TOF), the most common cyanotic congenital heart disease, is classically associated with decreased pulmonary blood flow. Classical TOF is characterized by antegrade pulmonary blood flow and right ventricular outflow tract obstruction at varying levels. In the modern era, most children with TOF undergo definitive intracardiac repair during infancy, and pulmonary artery hypertension (PAH) is virtually unheard of in postoperative TOF in the absence of major aortopulmonary collaterals. We report the circumstances in which PAH can occur after definitive repair of classical TOF in the modern era.</p>","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":"53 5","pages":"358-361"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144562518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spontaneous Partial Rupture of the Long Proximal Biceps Tendon in a Patient with Variant Transthyretin Amyloid Cardiomyopathy Due to a Heterozygous c148G>A p.Val50Leu Mutation.","authors":"Belma Kalaycı, Ezgi Polat Ocaklı, Nur Aydınbelge Dizdar, Esin Kurtuluş Öztürk, Taha Bahsi, Özlem Özmen","doi":"10.5543/tkda.2024.71970","DOIUrl":"10.5543/tkda.2024.71970","url":null,"abstract":"<p><p>Variant transthyretin amyloid cardiomyopathy (ATTRv-CM) is a rare disease caused by a genetic mutation in the ATTR gene. Due to the pathogenic mutation, transthyretin tetramers lose their structural stability and misfold, leading to the accumulation of amyloid fibrils in various tissues, particularly in the heart. The clinical progression of ATTRv-CM varies depending on the specific mutation. Data on ATTR gene mutations in Türkiye are limited. This paper presents a case of spontaneous biceps tendon rupture, identified prior to diagnosis, in a patient with ATTRv-CM carrying a heterozygous c148G>A pVal50Leu mutation.</p>","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":"53 5","pages":"362-366"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144562521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Questionnaire of Current Situation in Pediatric Cardiac Intensive Care in Türkiye.","authors":"Ayşe Filiz Yetimakman, Gökçen Özçifçi, Merve Havan, Mehmet Çeleğen, Nagehan Aslan, Murat Kangın, Mehmet Boşnak, Tanıl Kendirli, Ayşe Berna Anıl","doi":"10.5543/tkda.2025.35063","DOIUrl":"https://doi.org/10.5543/tkda.2025.35063","url":null,"abstract":"<p><strong>Objective: </strong>To enhance the results in pediatric cardiac intensive care patients, it is essential to determine the personnel, organisation and equipment status that require improvement. This study aimed to evaluate the current status in the units where pediatric cardiac intensive care patients are admitted, in Türkiye.</p><p><strong>Method: </strong>The study was carried out by means of an online questionnaire form delivered to the chief physicians of intensive care units. The number of patients admitted in the intensive care unit, scope of the surgeries, the number and specialities of physicians and staff who are involved, their roles in patient care, as well as the use of monitorisation methods were defined. Descriptive statistics were applied to the results.</p><p><strong>Results: </strong>The intensive care units are most commonly found in educational institutions and there is a high rate of subspecialty training clinics. The majority of the units are medical and surgical mixed units (76%) and pediatric-only (96%). Pediatric intensive care specialists are most often asserted as the primary responsible physician (48%). The average number of surgeries and annual number of admitted patients are variable among the institutions. Interventional procedures are performed (92%) and cardiac mechanical support systems are used (84%) in the vast majority of the institutions.</p><p><strong>Conclusion: </strong>There is great heterogeneity in patient volumes, personnel status and organisation styles of the units in which pediatric cardiac intensive care patients are admitted. In the future, all these types of patients should be cared for in pediatric-only units and physicians specialized in Pediatric Intensive Care should be present in the teams caring for these patients.</p>","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":"53 5","pages":"336-341"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144562523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Turkish Version of the Cardiac Distress Inventory and Cardiac Distress Inventory Short Form: A Validity and Reliability Study.","authors":"Füsun Afşar, Ece Alagöz, Asibe Özkan, Özlem Köksal, Mehmet Şeker, Ahmet İlker Tekeşin, Habip Yılmaz, Alun C Jackson, Michael Le Grande","doi":"10.5543/tkda.2025.94460","DOIUrl":"https://doi.org/10.5543/tkda.2025.94460","url":null,"abstract":"<p><strong>Objective: </strong>Increased negative moods such as anxiety, depression and fear of recurrence of cardiac events after a cardiac event, make it difficult to comply with lifestyle recommendations and drug therapy. Conducting screenings for cardiac distress and ensuring appropriate referrals are made constitute a crucial aspect of maintaining a healthy lifestyle post-illness. The Cardiac Distress Inventory has made it possible to assess cardiac patients psychologically and emotionally. The objective of this study was to provide a validity and reliability assessment of the original form Cardiac Distress Inventory (CDI) and short form (CDI-SF), in Turkish.</p><p><strong>Method: </strong>The inventory was administered face to face to a total of 417 participants (336 CDI/81 CDI-SF) who were hospitalized with the diagnosis of acute coronary syndrome and volunteered to participate in the study. Validity data was assessed using Exploratory Factor Analysis (EFA), Rasch, Confirmatory Factor Analysis (CFA), reliability by McDonald's Omega (ω), Pearson correlation coefficient and discriminability by Receiver operating characteristic (ROC) analysis.</p><p><strong>Results: </strong>The two CDI were a high level of reliability. The factor structure and factor loadings of the CDI were not compatible with the original. The goodness of fit estimated by validity (CFA-EFA) was also not confirmed. The values of RMSEA, χ2/df and CFI indices suggest that it is not suitable for Türkiye. However, in the cross-cultural adaptation, validity and reliability study of the CDI-SF, it was concluded that the construct validity and internal consistency were high and could be used as a unidimensional scale. The inventory will be made freely available to clinicians and researchers.</p><p><strong>Conclusion: </strong>CDI-SF provides a specific, pragmatic and reliable measurement of cardiac distress, adapted to common heart diseases. It serves as an effective screening tool in cardiac clinical management by demonstrating strong psychometric properties.</p>","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":"53 5","pages":"342-349"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144562524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Rare Aortic Arch Anomaly in the Light of A New Nomenclature.","authors":"Serdar Kula, Öznur Leman Boyunağa, Sertaç Bekir Cömert, Ege Kula","doi":"10.5543/tkda.2025.22544","DOIUrl":"https://doi.org/10.5543/tkda.2025.22544","url":null,"abstract":"","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":"53 5","pages":"369"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144562458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comments on Cardiology.","authors":"Ertan Ural","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":"53 5","pages":"378-379"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144562460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can the Serum Uric Acid to Albumin Ratio be Reliable Enough to Determine Prognosis in Hypertensive Patients in the Future?","authors":"Halit Emre Yalvaç, Bülent Görenek","doi":"10.5543/tkda.2025.52389","DOIUrl":"https://doi.org/10.5543/tkda.2025.52389","url":null,"abstract":"","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":"53 5","pages":"374-375"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144562459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Heavy Metal Accumulation in Cardiovascular Tissues: Rethinking Pathogenesis and Treatment Paradigms.","authors":"Ayhan Olcay, Serdar Baki Albayrak, Onur Yolay, Vedat Öztürk","doi":"10.5543/tkda.2025.36607","DOIUrl":"https://doi.org/10.5543/tkda.2025.36607","url":null,"abstract":"","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":"53 5","pages":"301-303"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144562515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incremental Diagnostic Value of Computed Tomography Attenuation in Differentiating Malignant Pericardial Effusion: A Retrospective Observational Study.","authors":"Duygu İnan, Ayse İrem Demirtola Mammadli, Gamze Gençol Akçay, Ali Fuat Tekin, Anar Mammadli","doi":"10.5543/tkda.2025.70300","DOIUrl":"10.5543/tkda.2025.70300","url":null,"abstract":"<p><strong>Objective: </strong>Malignant pericardial effusion (MPE) is associated with poor prognosis and frequently presents as cardiac tamponade. While cytology is the diagnostic gold standard, its sensitivity is limited. Computed tomography (CT) attenuation, measured in Hounsfield Units (HU), may reflect fluid composition and assist in the non-invasive differentiation of MPE.</p><p><strong>Method: </strong>This retrospective, single-center study included 102 patients who underwent percutaneous pericardiocentesis and thoracic CT. Patients were classified as having malignant or non-malignant effusion based on pathological findings. CT attenuation was measured at three standardized axial levels. Diagnostic performance was assessed using multivariate logistic regression and receiver operating characteristic (ROC) analysis. Two predictive models were compared: Model 1 (clinical and laboratory variables) and Model 2 (Model 1 + CT attenuation).</p><p><strong>Results: </strong>MPE was diagnosed in 44 patients (43.1%). CT attenuation values were significantly higher in the MPE group (median 24.4 HU vs. 9.3 HU, P < 0.001). On multivariate analysis, male sex, elevated pericardial fluid protein, low glucose, and high lactate dehydrogenase were independent predictors of MPE. CT attenuation also emerged as an independent predictor when added to the model (Model 2) (odds ratio [OR] = 1.076, 95% confidence interval [CI]: 1.026-1.128, P = 0.003). The inclusion of CT attenuation improved the model's diagnostic performance (area under the curve [AUC]: 0.893 for Model 2 vs. 0.860 for Model 1). Model 2 demonstrated superior diagnostic performance (AUC = 0.893), with a CT attenuation cut-off of 16.45 HU yielding a sensitivity of 88.2% and a specificity of 78.3%.</p><p><strong>Conclusion: </strong>CT attenuation provides incremental diagnostic value in identifying MPE when combined with conventional clinical and biochemical parameters. In settings where rapid diagnosis is critical, its non-invasive and reproducible nature may support early detection of malignant conditions.</p>","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":"53 5","pages":"304-311"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144562516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of QTc Interval, Tp-e Interval, Tp-e/QT Ratio and Tp-e/QTc Ratio in Patients with Autosomal Dominant Polycystic Kidney Disease.","authors":"Nart Zafer Baytugan, Kemal Mağden","doi":"10.5543/tkda.2025.53768","DOIUrl":"https://doi.org/10.5543/tkda.2025.53768","url":null,"abstract":"<p><strong>Objective: </strong>Autosomal dominant polycystic kidney disease (ADPKD) is a complex, progressive condition that primarily involves the kidneys but may also affect other systems, namely the cardiovascular system. It is characterized by the growth of cysts, leading to decreased renal function and finally, to chronic kidney disease. While renal symptoms are the primary focus of treatment, cardiovascular complications play a significant role in morbidity and mortality and there is a paucity of information regarding the risk of arrhythmias in these patients. The evaluation of myocardial repolarization was conducted through a variety of methodologies, including Tp-e, QTc and QT interval assessment. An increasing amount of data suggests that malignant ventricular arrhythmias are linked to a higher Tp-e/QT ratio.</p><p><strong>Method: </strong>This case-control study of 31 adult patients diagnosed with ADPKD was conducted between May 2021 and April 2024. Control group patients were selected using propensity score matching and were considered to minimize confounding factors. All participants underwent electrocardiography and transthoracic echocardiography studies.</p><p><strong>Results: </strong>Patients with ADPKD had substantially higher QTc intervals, Tp-e intervals, Tp-e/QT ratio and Tp-e/QTc ratio, than the control group (all P = 0.001). Correlation analysis revealed significant negative correlations between estimated glomerular filtration rate (ml/min./1.73 m2) and QTc interval (P = 0.002), Tp-e interval (P = 0.003), Tp-e/QT ratio (P = 0.042) and Tp-e/QTc ratio (P = 0.021) in patients with ADPKD.</p><p><strong>Conclusion: </strong>According to resting ECG findings, patients with ADPKD were predisposed to sudden cardiac death.</p>","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":"53 5","pages":"328-335"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144562513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}