Yelda Saltan Özateş, Ahmet Yener Odabaşı, Ufuk Yıldız, Duygu Genç Albayrak, Duygu İnan, Serap Baş, Asiye Işın Doğan Ekici, Mehmet Emin Demir, Ahmet İlker Tekkeşin
{"title":"Recovery of Myocardial Functions After Kidney Transplantation in Patients with Heart Failure Due to Uremic Cardiomyopathy.","authors":"Yelda Saltan Özateş, Ahmet Yener Odabaşı, Ufuk Yıldız, Duygu Genç Albayrak, Duygu İnan, Serap Baş, Asiye Işın Doğan Ekici, Mehmet Emin Demir, Ahmet İlker Tekkeşin","doi":"10.5543/tkda.2024.93263","DOIUrl":"10.5543/tkda.2024.93263","url":null,"abstract":"<p><strong>Objective: </strong>Although left ventricular hypertrophy frequently accompanies end-stage renal disease, heart failure (HF) with reduced ejection fraction (EF) is also observed in a subset of patients. In those patients kidney transplantation (KT) is generally avoided due to an increased risk of mortality in addition to the risks associated with HF. This prospective study was designed to follow patients with HF who were being prepared for KT.</p><p><strong>Methods: </strong>Twenty-five patients with HF due to uremic cardiomyopathy (UC) who had suitable donors (Group 1), 22 patients with HF who could not undergo KT due to a lack of kidney donors (Group 3), and 25 KT candidates with normal ventricular function (Group 2) were included in the study. Left ventricular ejection fraction (LVEF), left atrial diameter (LAD), mitral annular systolic velocity (Sm), left ventricular global longitudinal strain (GLS), and left ventricular mass index (LVMI) values were recorded across four sessions, from pre-transplant to six months post-transplantation. Endomyocardial biopsy was performed for detailed examination of the myocardium in patients in Group 1 and Group 3, and cardiac magnetic resonance imaging (MRI) was performed in all three groups before transplantation.</p><p><strong>Results: </strong>In Group 1, LVEF, Sm, and left ventricular global longitudinal strain (LV-GLS) increased significantly, while LAD and LVMI decreased, all reaching normal levels. In contrast, no changes were observed in Group 3 and Group 2 (P < 0.01 for LVEF, P < 0.01 for GLS, P < 0.01 for LAD, and P < 0.01 for LVMI measurements). No differences in cardiac MRI and biopsy findings were observed between Group 1 and Group 3.</p><p><strong>Conclusion: </strong>Since myocardial function improved significantly and normalized in all patients with HF, it has been demonstrated that UC can be substantially reversible when treated with KT.</p>","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":"53 1","pages":"1-12"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142967644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reply to the Letter to the Editor: ''The Need for a New Description of Red Flags in Cardiac Amyloidosis in Turkish Population''.","authors":"Selda Murat, Halit Emre Yalvaç, Yüksel Çavuşoğlu","doi":"10.5543/tkda.2024.84415","DOIUrl":"https://doi.org/10.5543/tkda.2024.84415","url":null,"abstract":"","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":"53 1","pages":"82-83"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142967646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
İrem Yılmaz, Mustafa Oğuz, Almina Erdem, Mert Babaoğlu, Mehmet Uzun
{"title":"The Need for a New Description of Red Flags in Cardiac Amyloidosis in Turkish Population.","authors":"İrem Yılmaz, Mustafa Oğuz, Almina Erdem, Mert Babaoğlu, Mehmet Uzun","doi":"10.5543/tkda.2024.14042","DOIUrl":"https://doi.org/10.5543/tkda.2024.14042","url":null,"abstract":"","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":"53 1","pages":"80-81"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142967648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hypereosinophilic Syndrome Complicated by Eosinophilic Myocarditis: Embolic Stroke or Eosinophilic Stroke? A Case Report.","authors":"Amirreza Sajjadieh Khajouei, Marzieh Tajmirriahi, Zahra Payandeh, Mahsa Amirhajlou Mashhadi, Nahid Shirani, Seyedeh Mahnaz Mirbod","doi":"10.5543/tkda.2024.46487","DOIUrl":"https://doi.org/10.5543/tkda.2024.46487","url":null,"abstract":"<p><p>Hypereosinophilic syndrome (HES) is traditionally described as chronic peripheral eosinophilia with involvement of various organs and systems, including the heart and nervous system. In this report, we describe cardiac involvement and border zone stroke in a patient with idiopathic HES. A 37-year-old woman presented with sudden right-sided weakness and slurred speech, which began four days before admission, accompanied by palpitations, retrosternal exertional chest discomfort, dry cough, and progressive shortness of breath over approximately two months. Preliminary studies showed an increased number of white blood cells with eosinophilia. Further diagnostic investigation revealed apical thrombosis in both ventricles of the heart and moderate left ventricular systolic dysfunction. Magnetic resonance imaging of the brain indicated multifocal infarctions in the anterior and posterior border zones, as well as both cerebellar hemispheres, predominantly on the left side. Consequently, the patient was diagnosed with idiopathic HES and treated with corticosteroids, cyclophosphamide, anticoagulants, and medications for heart failure. She responded well both clinically and hematologically. Our case highlights the importance of multiple imaging modalities in diagnosing eosinophilic endomyocarditis and the impact of timely medical treatment to prevent disease progression.</p>","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":"53 1","pages":"62-67"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142967640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Novel Electrocardiographic Marker for Predicting Total Mortality in Ischemic Stroke: Frontal QRS-T Angle.","authors":"Songül Usalp, Bayram Bağırtan","doi":"10.5543/tkda.2024.71138","DOIUrl":"https://doi.org/10.5543/tkda.2024.71138","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to investigate the relationship between mortality and the frontal QRS-T angle (FQRS-TA), obtained by calculating the absolute difference between the QRS and T waves electrocardiographically (ECG), in patients diagnosed with ischemic stroke (IS).</p><p><strong>Methods: </strong>This research is a retrospective and cross-sectional study. The diagnosis of IS was confirmed through brain imaging and physical examination. Patients with sinus rhythm were included in the study. The FQRS-TA was measured by calculating the absolute difference between the QRS-axis and the T-axis, as automatically measured on the ECG. Patients were divided into two groups: those who died within five years and those who survived, and the groups were compared.</p><p><strong>Results: </strong>A total of 322 patients with IS were included in the study, of whom 290 survived, and 32 died. Age, creatinine level, PR interval, QRS duration, corrected QT (cQT) value, and FQRS-TA value were found to be higher in the deceased group. Cox regression analyses were performed to examine the association between predictors of stroke-related mortality. Age [hazard ratio (HR): 1.091, 95% (1.045-1.140), P < 0.001], high-density lipoprotein (HDL) [HR: 0.914, 95% (0.875-0.955), P < 0.001], and FQRS-TA [odds ratio (OR): 1.011, 95% (1.003-1.019), P = 0.007] were associated with mortality. A FQRS-TA of 68 degrees or higher was associated with cumulative mortality in the Kaplan-Meier survival analysis (log rank [Mantel-Cox] test: P = 0.001).</p><p><strong>Conclusion: </strong>In this study, increased FQRS-TA was found to be associated with mortality in patients with IS. ECG parameters are simple and time-efficient measurements that can provide important prognostic information. To the best of our knowledge, this research is the first study to examine the relationship between FQRS-TA and mortality in patients with IS.</p>","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":"53 1","pages":"29-34"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142967687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Associations Between Upper Extremity Function, Activities of Daily Living, and Functional Capacity in Patients with Heart Failure with Reduced Ejection Fraction.","authors":"Aylin Tanrıverdi Eyolcu, Buse Özcan Kahraman, Ebru Özpelit, Serap Acar, Bihter Şentürk, İsmail Özsoy, Bahri Akdeniz, Mehmet Birhan Yılmaz, Sema Savcı","doi":"10.5543/tkda.2024.79916","DOIUrl":"https://doi.org/10.5543/tkda.2024.79916","url":null,"abstract":"<p><strong>Objective: </strong>Limited information is available regarding the associations between upper extremity function, activities of daily living (ADLs), and functional capacity in patients with heart failure with reduced ejection fraction (HFrEF). This study aimed to investigate the associations between upper extremity function, ADLs, and functional capacity in patients with HFrEF.</p><p><strong>Methods: </strong>This cross-sectional study included 31 patients with HFrEF. Demographic, anthropometric, and clinical data were recorded. Upper extremity function and ADLs were evaluated using the 6-Minute Pegboard and Ring Test (6PBRT) and the Glittre Activities of Daily Living Test (TGlittre), respectively. The 6-Minute Walk Test (6MWT) was administered to measure functional capacity. Heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP), peripheral oxygen saturation (SpO2), dyspnea, and fatigue were assessed at the beginning and end of each test.</p><p><strong>Results: </strong>The 6PBRT was significantly correlated with TGlittre (rho = -0.718, P < 0.001) and 6-minute walk distance (6MWD) (r = 0.546, P = 0.001). A significant correlation was also found between TGlittre and 6MWD (rho = -0.810, P < 0.001). Changes in HR, SBP, and dyspnea were significantly different across the 6PBRT, TGlittre, and 6MWT (P < 0.05).</p><p><strong>Conclusion: </strong>This study indicates that upper extremity function is associated with ADLs and functional capacity in patients with HFrEF. The 6PBRT requires lower cardiopulmonary demand than TGlittre and 6MWT in this patient population.</p>","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":"53 1","pages":"22-28"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142967637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}