Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir最新文献

{"title":"The Hemoglobin, Albumin, Lymphocyte, and Platelet Score as a Simple Blood-Based Predictor of Residual Coronary Disease Burden in Diabetic Patients with Non-ST-Elevation Myocardial Infarction.","authors":"İlke Erbay, Pelin Aladağ","doi":"10.5543/tkda.2025.71080","DOIUrl":"https://doi.org/10.5543/tkda.2025.71080","url":null,"abstract":"<p><strong>Objective: </strong>Patients with type 2 diabetes mellitus (T2DM) and non-ST-elevation myocardial infarction (NSTEMI) are at increased risk of incomplete revascularization and adverse outcomes. Simple biomarkers to predict residual disease burden and prognosis are clinically valuable. The hemoglobin, albumin, lymphocyte, and platelet (HALP) score reflects inflammation and nutritional status. This study evaluated the association of the HALP score with the residual Synergy Between Percutaneous Coronary Intervention with Taxus and Cardiac Surgery (SYNTAX) score (rSS) and 12-month major adverse cardiovascular events (MACE) in T2DM patients with NSTEMI.</p><p><strong>Method: </strong>This retrospective study included 210 diabetic patients. Participants were stratified into three groups based on rSS (0, 1-8, > 8). HALP scores were calculated from admission laboratory values, and outcomes were followed for 12 months. Associations between HALP and rSS were assessed using Spearman correlation and multivariable regression. Receiver operating characteristic (ROC) analysis identified a HALP cut-off value for predicting high rSS. The prognostic value for MACE was evaluated using Cox regression and Kaplan-Meier analysis.</p><p><strong>Results: </strong>HALP scores were significantly lower in patients with rSS > 8 (P < 0.001) and were negatively associated with rSS (β = -0.344, P < 0.001). The optimal HALP score cut-off for predicting rSS > 8 was 2.96, with 78% sensitivity and 77% specificity. Patients with HALP ≤ 2.96 had a higher prevalence of rSS > 8 (43.7% vs. 6.5%) and experienced more MACE over 12 months (29.6% vs. 13.7%, P = 0.005). In Cox analysis, a low HALP score (≤ 2.96) was an independent predictor of MACE, along with age and C-reactive protein (CRP) levels (hazard ratio = 1.916, P = 0.045).</p><p><strong>Conclusion: </strong>Lower HALP scores are associated with higher residual disease burden and worse outcomes. The HALP score may serve as a practical tool for risk stratification in patients with diabetic NSTEMI.</p>","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144796599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Percutaneous Intervention for Left Internal Mammary Artery Side Branch, Subclavian, and Coronary Artery Stenosis in Chronic Coronary Syndrome.","authors":"Mert Doğan, Ahmet Kıvrak, Uğur Canpolat, Ahmet Hakan Ateş, Kudret Aytemir","doi":"10.5543/tkda.2025.17608","DOIUrl":"https://doi.org/10.5543/tkda.2025.17608","url":null,"abstract":"","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144791158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Noonan Syndrome Mimicking Acute Coronary Syndrome.","authors":"Mustafa Yılmaz, Arda Güler, Elif Ayduk Gövdeli, Mehmet Karacan, Gamze Babur Guler","doi":"10.5543/tkda.2025.48459","DOIUrl":"https://doi.org/10.5543/tkda.2025.48459","url":null,"abstract":"<p><p>Noonan syndrome is a genetic disorder that can present with a wide range of clinical manifestations, making diagnosis challenging. This article presents the case of a 29-year-old male who presented with chest pain and ST-segment elevation, initially raising suspicion for acute coronary syndrome. However, coronary angiography revealed only ectasia of the coronary arteries, with no other pathological findings. A detailed physical examination and echocardiography revealed a pulmonary murmur, pectus excavatum, and café-au-lait spots. Additionally, both echocardiography and cardiac magnetic resonance imaging (MRI) showed localized left ventricular hypertrophy. Genetic testing identified a heterozygous missense variant in the PTPN11 gene, leading to the diagnosis of Noonan syndrome. This case highlights the importance of thorough physical examination and multimodal imaging in the diagnosis of Noonan syndrome.</p>","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144762926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of CHA2DS2-VASc, C2HEST, HAT2CH2, SYNTAX, GRACE, and SYNTAX II Scores for Predicting New-Onset Atrial Fibrillation Complicating Acute Myocardial Infarction.","authors":"Nazile Bilgin Doğan, Abdullah Kadir Dolu, Selim Ekinci, Ersin Çağrı Şimşek","doi":"10.5543/tkda.2025.38852","DOIUrl":"https://doi.org/10.5543/tkda.2025.38852","url":null,"abstract":"<p><strong>Objective: </strong>This study evaluated the most effective scoring system for predicting new-onset atrial fibrillation (NOAF) during acute myocardial infarction (AMI). Identifying the best predictive tool may help clinicians select the most appropriate personalized treatment based on individual risk scores to prevent NOAF complicating AMI.</p><p><strong>Method: </strong>A total of 2,206 patients diagnosed with AMI between June 2021 and January 2023 were included in this study. After excluding cases with missing data, univariable and multivariable analyses were conducted on 1,672 patients to assess the association between baseline characteristics and the development of atrial fibrillation. The CHA2DS2-VASC (Congestive heart failure, Hypertension, Age ≥ 75 years, Diabetes mellitus, Stroke/TIA/thromboembolism, Vascular disease, Age 65-74 years, Sex category), C2HEST (Coronary artery disease, Chronic obstructive pulmonary disease, Hypertension, Elderly [age ≥ 75], Systolic heart failure, Thyroid disease), HAT2CH2 (Hypertension, Age > 75, Stroke/TIA, Chronic obstructive pulmonary disease, Heart failure), SYNTAX (Synergy Between PCI with Taxus and Cardiac Surgery), GRACE 2.0 (Global Registry of Acute Coronary Events), and SYNTAX II scores were calculated for each patient.</p><p><strong>Results: </strong>Receiver operating characteristic (ROC) analysis showed that the SYNTAX score (SxS) had the highest predictive value for NOAF during AMI, with an area under the curve (AUC) of 0.785 (95% confidence interval [CI]: 0.767-0.802, P < 0.001), followed by the SYNTAX II score (SxSII) with an AUC of 0.747 (95% CI: 0.728-0.765, P < 0.001), and the GRACE 2.0 risk score (RS) with an AUC of 0.740 (95% CI: 0.721-0.758, P < 0.001). It was shown that the modified scores (created by incorporating hemoglobin A1c [HbA1c] levels), the primary independent predictive parameter in this study, into the existing risk models demonstrated higher predictive value for NOAF (C-statistic: 0.784-0.794).</p><p><strong>Conclusion: </strong>Combining HbA1c levels with SxS yielded the highest diagnostic performance for predicting NOAF during AMI. In this study, while SxS outperformed other risk models, the GRACE 2.0 and SxSII scores also demonstrated relatively strong predictive value and were superior to the CHA2DS2-VASC, C2HEST, and HAT2CH2 scores for predicting NOAF in the setting of AMI.</p>","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144762927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors Affecting QT Interval in Patients with Type 2 Diabetes Mellitus and the Effect of Sodium-Glucose Cotransporter 2 Inhibitors.","authors":"Ali Çoner, Can Ramazan Öncel, Cemal Köseoğlu","doi":"10.5543/tkda.2025.70970","DOIUrl":"https://doi.org/10.5543/tkda.2025.70970","url":null,"abstract":"","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144746632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Would the Hemoglobin, Albumin, Lymphocyte, and Platelet Score Help Predict Atrial Fibrillation Recurrence After Cryoballoon Ablation?","authors":"Uğur Canpolat","doi":"10.5543/tkda.2025.50051","DOIUrl":"https://doi.org/10.5543/tkda.2025.50051","url":null,"abstract":"","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144746634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implications of Procedure of Thoracic Endovascular Aortic Repair on Left Ventricular Global Longitudinal Strain.","authors":"Taner Şahin, Mehmet Çiçek, Sezgin Atmaca, Ahmet Anıl Şahin, Ömer Çelik","doi":"10.5543/tkda.2025.22994","DOIUrl":"https://doi.org/10.5543/tkda.2025.22994","url":null,"abstract":"<p><strong>Objective: </strong>Aorta, particularly in its proximal segments, expands during systole to store blood, which is subsequently released into the peripheral circulation during diastole, morphologically and histologically. This function, referred to as the \"Windkessel effect,\" ensures continuous and regular blood flow in the peripheral circulation. Thoracic Endovascular Aortic Repair (TEVAR) was introduced in the literature as a treatment for Type B aortic dissections (TBAD). In patients who undergo TEVAR, the placement of a stent graft in the proximal segments of the aorta, which are responsible for the highest capacity of blood storage and elasticity, may disrupt this function. Consequently, this alteration may lead to increased afterload and, over the long term, impair left ventricular systolic function. Previous studies have demonstrated that measurements of left ventricular global longitudinal strain (LVGLS) can detect early systolic dysfunction before any significant changes in left ventricular ejection fraction (LVEF) occur. The aim of this study is to compare preoperative and postoperative LVGLS measurements in patients who underwent TEVAR, thereby illustrating changes in LVGLS associated with the procedure.</p><p><strong>Methods: </strong>Patients who underwent TEVAR for TBAD or Thoracic Aortic Aneurysm (TAA) were included in the study. Patients with malignancy, advanced valvular pathology, end-stage chronic kidney disease, liver failure, or heart failure were excluded. Preoperative data, including comorbidities, medication use, blood parameters, electrocardiography findings, transthoracic echocardiography images, and LVGLS values, were recorded. These parameters were then compared with the values obtained at the postoperative 3-month outpatient follow-up.</p><p><strong>Results: </strong>After TEVAR procedure, a significant decrease in LVGLS was observed (p<0.001). A strong correlation was found between the change in mean arterial pressure (MAP) and the reduction in LVGLS (ρ=0.555, p=0.017). Postoperatively, significant increases were noted in systolic blood pressure (SBP) and MAP (both p<0.001). No significant differences were observed in other parameters before and after the procedure.</p><p><strong>Conclusion: </strong>In our study, a significant increase in SBP and MAP, along with a notable decrease in LVGLS values, were observed following TEVAR procedure. A significant and strong correlation was identified between the increase in MAP and the decrease in LVGLS.</p>","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144746633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can Artificial Intelligence Replace Human Peer Review in Cardiovascular Journals?","authors":"Sefa Tatar","doi":"10.5543/tkda.2025.67002","DOIUrl":"https://doi.org/10.5543/tkda.2025.67002","url":null,"abstract":"","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144746631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Local Anesthetic-Related Methemoglobinemia During Cardiac Device Implantation; A Retrospective Registry: The LAMDA Study-Uncorrected Proof.","authors":"Nazif Yalçın, Fatih Kahraman, Mehmet Ali Astarcıoğlu, Taner Şen","doi":"10.5543/tkda.2025.62884","DOIUrl":"https://doi.org/10.5543/tkda.2025.62884","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to determine the frequency of methemoglobin development and identify associated factors in patients undergoing Implantable Cardioverter-Defibrillator (ICD) and Cardiac Resynchronization Therapy (CRT) procedures with the local anesthetic prilocaine.</p><p><strong>Method: </strong>Data from 64 patients were analyzed. The patients' methemoglobin levels before and after the procedure were measured and compared. The relationships between the results and factors such as creatinine, hemoglobin, BMI, and the amount of prilocaine used were examined. Exclusion criteria included: age under 18 years, pregnancy, breastfeeding, malignancy, chemotherapy, hemoglobin chain disorders, liver failure, and renal failure (GFR <60 ml/min), chronic obstructive pulmonary disease, other hypoxic lung diseases and smoker patients.</p><p><strong>Results: </strong>Methemoglobin levels were significantly higher in the first hour after the procedure (p < 0.001). Oxygen saturation levels were significantly lower during the first hour post-procedure (p < 0.001). In the group with elevated methemoglobin levels after the procedure, creatinine levels were significantly higher (p < 0.001), while BMI (p < 0.001) and hemoglobin levels (p < 0.001) were significantly lower. No significant relationship was found with ALT levels (p = 0.425).</p><p><strong>Conclusion: </strong>While significant methemoglobin elevation was observed following ICD/CRT procedures with prilocaine, clinically significant methemoglobinemia cases are rare. A significant relationship was identified between methemoglobin elevation and BMI, hemoglobin, and creatinine.</p>","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144610835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Rare Anatomical Variant: Cryoballoon Ablation of Accessory Pulmonary Vein Originating from the Left Atrial Roof: A Case Report.","authors":"Koray Kalenderoğlu, Mert İlker Hayıroğlu, Melih Öz, Kadir Gürkan","doi":"10.5543/tkda.2025.35324","DOIUrl":"https://doi.org/10.5543/tkda.2025.35324","url":null,"abstract":"<p><p>We administered cryoballoon ablation to a 61-year-old female patient for recurrent paroxysmal atrial fibrillation. Contrast-enhanced CT angiography used to assess the patient's pulmonary vein anatomy prior to cryoballoon ablation revealed an accessory pulmonary vein emanating from the left atrial roof. Cryoballoon ablation was successfully performed on this accessory vein, which is rarely seen in the literature for the first time.</p>","PeriodicalId":94261,"journal":{"name":"Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144586037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}