Canadian Journal of Kidney Health and Disease最新文献

{"title":"Conference Report-The Past, Current, and Future Challenges in Transplantation: A Festschrift in Honor of Professor Paul Anthony Keown.","authors":"John Gill, Calvin Stiller, James Lan, Anthony Jevnikar, Philip F Halloran, David Rush, Peter Nickerson, Edward Cole, Arthur J Matas, Richard Formica, Deirdre Sawinski, Christopher D Blosser, Roslyn B Mannon, Paul A Keown","doi":"10.1177/20543581261434082","DOIUrl":"https://doi.org/10.1177/20543581261434082","url":null,"abstract":"<p><strong>Purpose: </strong>Canadian researchers have made significant contributions to the advancement of organ transplantation globally. The COVID-19 pandemic made transparent the importance of reflecting on our accomplishments and the current and future challenges that limit the lives of our patients and to celebrate individual and collective achievement.</p><p><strong>Sources of information/methods: </strong>On October 6, 2025, thought leaders in the field of organ transplantation assembled in Vancouver to recognize the contributions of Paul Keown, a clinician scientist and translational researcher, whose work has directly impacted thousands of transplant recipients worldwide.</p><p><strong>Key findings: </strong>This article summarizes the invited speaker presentations and represents a unique opportunity to celebrate the past and to focus on current challenges and future opportunities to advance the field of organ transplantation.</p>","PeriodicalId":9426,"journal":{"name":"Canadian Journal of Kidney Health and Disease","volume":"13 ","pages":"20543581261434082"},"PeriodicalIF":1.5,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13125847/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147811512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Multipronged Intervention to Improve Outpatient Care Following Hospitalization With Acute Kidney Injury: An Implementation Study Protocol.","authors":"Michelle M Y Wong, Peter Birks, Omosomi Enilama, Janelle S W Yu, Anurag Singh, Adeera Levin","doi":"10.1177/20543581261429009","DOIUrl":"10.1177/20543581261429009","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Acute kidney injury (AKI)-related hospitalizations are associated with long-term health consequences, but post-AKI management and monitoring in the outpatient primary care setting are suboptimal. Documentation and communication about in-hospital AKI episodes to patients' primary care providers are often inadequate. Awareness of AKI among patients is generally poor.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To develop a multifaceted intervention package to improve post-AKI care, to evaluate its implementation using feasibility and process metrics, and to observe its short-term effectiveness.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Design: &lt;/strong&gt;Mixed-methods feasibility study with type 3 hybrid implementation/effectiveness design.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Participants: &lt;/strong&gt;Kidney specialist physicians on inpatient consultation service at three hospital sites in British Columbia (in New Westminster, Prince George, Vancouver) will deliver the intervention package to patients with AKI and their primary care providers.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Measurements: &lt;/strong&gt;Implementation outcomes include reach, adoption, fidelity, and sustainment of the intervention. Implementation determinants, including acceptability, adaptability, feasibility, appropriateness, and satisfaction, will be assessed with surveys and focus groups with kidney specialist physicians, primary care providers, and patients/caregivers. Short-term effectiveness outcomes include: patient follow-up visits with primary care providers, and kidney lab testing at three months; AKI awareness and self-efficacy among primary care providers and patients.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;Guided by the Theoretical Domains Framework, we conducted focus groups with interest holders to identify the barriers, challenges, and needs in post-AKI care and then applied this information to develop an intervention package, including an AKI-specific discharge/sign-off template, a post-AKI medication management guide, educational websites for providers and patients, and a patient handout. In this six-month implementation feasibility study, the implementation strategies will be initiated sequentially at each site for four to eight weeks. Quantitative data will be collected via self-report, chart review, surveys, and website hits and analyzed using descriptive statistics. Postimplementation qualitative data will be collected from focus groups/interviews and will be analyzed by identifying codes and categorizing them into themes.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Limitations: &lt;/strong&gt;The study will take place in the setting of nephrology consultation services. Adaptations to implementation strategies would be required for delivery of the intervention by other inpatient providers.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;The study will evaluate feasibility and preliminary effectiveness of a multifaceted intervention aimed at improving care coordination between specialists and primary care providers and care transition following hospital discharge in pati","PeriodicalId":9426,"journal":{"name":"Canadian Journal of Kidney Health and Disease","volume":"13 ","pages":"20543581261429009"},"PeriodicalIF":1.5,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13091966/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147728393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Experiences of Patients With Chronic Kidney Disease Undergoing Hemodialysis: A Qualitative Study in Bangladesh.","authors":"Muhammed Arshad Ul Azim, Md Enamul Kabir, Md Obaidul Haque, Md Afzalul Bashar, Zannatul Ferdous, Banga Kamal Basu, Moyeenuddin Amin, Asma Begum, Kazi Maria Haque Semme, Syed Abdullah Jami, Nazim Uzzaman, Gm Monsur Habib","doi":"10.1177/20543581261429257","DOIUrl":"10.1177/20543581261429257","url":null,"abstract":"<p><strong>Background: </strong>Despite the increasing burden of chronic kidney disease (CKD) and its associated challenges, there is limited understanding of the lived experiences, awareness, and treatment perspectives of patients in Bangladesh.</p><p><strong>Objective: </strong>We aimed to explore the experiences of patients with CKD undergoing maintenance hemodialysis in Bangladesh, identifying key challenges and areas for improvement.</p><p><strong>Design: </strong>Descriptive qualitative study.</p><p><strong>Setting: </strong>Khulna, Bangladesh.</p><p><strong>Participants: </strong>Individuals with CKD undergoing maintenance hemodialysis.</p><p><strong>Methods: </strong>We recruited people with CKD undergoing maintenance hemodialysis from two tertiary hospitals in Khulna, Bangladesh, using purposive sampling. Semi-structured interviews were conducted, and the data were analyzed using Braun and Clarke's inductive thematic analysis approach.</p><p><strong>Results: </strong>We interviewed 16 participants with CKD. Our findings revealed that most participants had limited knowledge about chronic kidney disease and experienced delays in diagnosis. While maintenance hemodialysis provided temporary relief, it also resulted in considerable physical and emotional distress. Financial strain was a major concern, with many participants struggling to afford treatment. Accessibility issues, such as long waiting times and transportation challenges, were common. Participants expressed a strong desire for better service delivery and reduced treatment costs.</p><p><strong>Limitations: </strong>All participants were recruited from two tertiary care hospitals in Khulna, an urban setting, which may limit the applicability of the findings to other regions of Bangladesh.</p><p><strong>Conclusion: </strong>Our study underscores the need for improved financial support, enhanced mental health services, greater patient awareness, and healthcare policy reforms to alleviate the burden on patients with chronic kidney disease and improve their overall quality of life.</p>","PeriodicalId":9426,"journal":{"name":"Canadian Journal of Kidney Health and Disease","volume":"13 ","pages":"20543581261429257"},"PeriodicalIF":1.5,"publicationDate":"2026-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13084006/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147722051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predicting Three-Year Survival in Patients Receiving Maintenance Dialysis: An External Validation and Updated Multivariable Prediction Model for iChoose Kidney in Ontario, Canada.","authors":"Kyla L Naylor, Yuguang Kang, Eric McArthur, Amit X Garg, Rachel E Patzer, Susan McKenzie, S Joseph Kim, Matthew Weir, Seychelle Yohanna, Gregory Knoll, Darin Treleaven","doi":"10.1177/20543581261437298","DOIUrl":"https://doi.org/10.1177/20543581261437298","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;A significant barrier to kidney transplantation is limited knowledge about its potential benefits. To help patients who are receiving maintenance dialysis make more informed treatment decisions, a risk calculator (iChoose Kidney) was developed in the United States to provide individualized survival estimates for dialysis versus kidney transplantation. This tool was externally validated in Ontario, Canada, and was found to accurately predict mortality (Ontario version of the tool \"Dialysis vs. Kidney Transplant-Estimated Survival in Ontario Risk Calculator\"). The United States risk calculator has been updated to include additional variables (e.g., dialysis modality).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To externally validate the updated iChoose Kidney risk calculator in patients from Ontario, Canada, with kidney failure using more recent data, removing race (race in clinical algorithms may perpetuate racial bias in medicine) and using a refined cohort definition (i.e., restricting to patients with no recorded contraindications to transplant).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Design: &lt;/strong&gt;External validation study.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Setting: &lt;/strong&gt;Linked administrative health care databases from Ontario, Canada.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Patients: &lt;/strong&gt;24 793 patients receiving maintenance dialysis and 5398 kidney transplant recipients from January 1, 2011, to August 31, 2021.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Measurements: &lt;/strong&gt;Three-year mortality.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;Model discrimination was evaluated using the C-statistic. Calibration was assessed by comparing the observed versus predicted mortality risks, and further assessed by using loess-smoothed calibration plots. To address over- or under-prediction (calibration-in-the-large), intercepts were adjusted using a correction factor. In our updated model, we used logistic regression to calculate mortality risk, incorporating the following variables: sex assigned at birth (male vs female), age (continuous), cardiovascular disease, hypertension, diabetes, time on dialysis (i.e., &lt;6 months, 6 to 12 months, &gt;1 to 2 years, &gt;2 to 3 years, &gt;3 to 5 years, &gt;5 to 7 years, &gt;7 to 10 years, &gt;10 to 14 years, &gt;14 years), and dialysis modality (peritoneal dialysis, home hemodialysis, in-center dialysis). In a post-hoc analysis, we used the simplified equations from our original Canadian external validation study of the iChoose Kidney tool (i.e., age, sex, hypertension, diabetes, cardiovascular disease, time on dialysis [&lt;6 months, 6-12 months, &gt;12 months]), with removal of the race variable as the only modification.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;In the dialysis cohort, over a median follow-up of 2.5 years, 30.3% of patients died. In the kidney transplant recipient cohort, over a median follow-up of 2.9 years, 7.3% died. Our updated model had moderate discrimination (C-statistic for dialysis cohort: 0.67 [95% CI: 0.67, 0.68] and C-statistic for kidney transplant cohort: 0.76 [95% CI: 0.74, 0.79]). After rec","PeriodicalId":9426,"journal":{"name":"Canadian Journal of Kidney Health and Disease","volume":"13 ","pages":"20543581261437298"},"PeriodicalIF":1.5,"publicationDate":"2026-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13070169/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147670256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating the Kidney Research Scientist Core Education and National Training (KRESCENT) Program: A 20-Year Qualitative Thematic Analysis.","authors":"Ian D Petula, Alison F Chung, Jamie E Knight, Sunny Hartwig, Adeera Levin, Theone S E Paterson","doi":"10.1177/20543581261434652","DOIUrl":"https://doi.org/10.1177/20543581261434652","url":null,"abstract":"<p><strong>Background: </strong>The Kidney Research Scientist Core Education and National Training (KRESCENT) program was established to enhance kidney research capacity in Canada by providing salary support and specialized training for kidney researchers in Canada. This study is a qualitative evaluation to gain insight into participants' experiences in the program.</p><p><strong>Objective: </strong>To explore participants' perspectives of the KRESCENT program to (1) identify potential differences in perspectives between early and recent program cohorts and (2) understand perceived impact on participants' career trajectory and professional development.</p><p><strong>Design: </strong>A qualitative interview study using semi-structured interviews.</p><p><strong>Setting: </strong>Semi-structured interviews were conducted online via Zoom.</p><p><strong>Participants: </strong>Individuals who have previously completed, or who are currently enrolled in the KRESCENT program.</p><p><strong>Methods: </strong>Participants were selected through purposive sampling, and semi-structured interviews were conducted to explore their experiences in the program. Data were analysed using thematic analysis in NVivo software.</p><p><strong>Results: </strong>Participants (N = 30; M_age = 41.2, SD_age = 8.3, 53% Female) were interviewed, and the following emergent themes from the data were identified: (1) Navigating Expectations within KRESCENT, (2) Developing a Foundation for Success in Kidney Research, (3) Perceived Program Impact, (4) Fostering Multidisciplinary Collaboration and Diversity, (5) Considerations for Future Awardees.</p><p><strong>Limitations: </strong>The initial coding was conducted by a single researcher.</p><p><strong>Conclusions: </strong>This study highlights the long-term impact of the KRESCENT program on kidney research in Canada by exploring participants' experiences and valued program elements beyond traditional career milestones. Findings emphasize that structured funding programs enhanced with opportunities for mentorship, networking, and skill development significantly support career advancement. These results reinforce the importance of continued investment in KRESCENT to build kidney research capacity and suggest that similar training models could benefit other health research fields.</p>","PeriodicalId":9426,"journal":{"name":"Canadian Journal of Kidney Health and Disease","volume":"13 ","pages":"20543581261434652"},"PeriodicalIF":1.5,"publicationDate":"2026-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13065261/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147670043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perspectives of People Receiving Dialysis About Climate Change and Environmentally Sustainable Kidney Care: A Knowledge, Attitudes and Practices Survey in Canada.","authors":"Camilia Minville, Carven Cambry, Daphne Esquivel Sada, Éliane Boucher, Alexia Mihalache, Ximena Fabiola Iraheta Palacios, Shaifali Sandal, Caroline Stigant, Isabelle Ethier","doi":"10.1177/20543581261434815","DOIUrl":"https://doi.org/10.1177/20543581261434815","url":null,"abstract":"<p><strong>Background: </strong>Knowledge, attitudes and practices (KAP) of kidney care providers regarding climate change, environmental impacts of kidney care and environmentally sustainable kidney care have been assessed in diverse regions worldwide, but little is known about the perspectives of people who receive dialysis therapies. We aimed to assess the KAP of people on dialysis about these subjects.</p><p><strong>Methods: </strong>An electronic KAP survey, based on a previous survey of Canadian kidney care providers, was administered to people receiving all available dialysis modalities in a single center in Canada, from December 2024 to May 2025.</p><p><strong>Results: </strong>A total of 69 people responded to the survey, of whom 67% identified as men, and 70% were undergoing in-center hemodialysis (ICHD), 14% home hemodialysis (HHD) and 16% peritoneal dialysis (PD). Most (87%) of the respondents felt informed about climate change to at least an average degree. Nearly half were either extremely or very concerned about climate change (44%) and the waste generated by dialysis treatments (43%), and the levels of concern differed across dialysis modalities. Overall, 51% of respondents never felt guilt or anxiety related to the carbon footprint of dialysis treatment. However, there were significant differences (χ² test; <i>P</i> < .001) in the occurrence of these feelings depending on the dialysis modality (more frequent in people receiving home modalities, and more in PD than HHD). Most respondents were either very (45%) or slightly (45%) interested in obtaining more information about the themes explored in the survey.</p><p><strong>Conclusions: </strong>This survey showed that most respondents receiving a dialysis therapy felt informed and at least moderately concerned about climate change. Higher levels of concern about climate change and the amount of waste generated by dialysis treatment, as well as more frequent occurrence of guilt/anxiety about the carbon footprint of dialysis were observed in people on home therapies (PD and HHD) compared with ICHD.</p>","PeriodicalId":9426,"journal":{"name":"Canadian Journal of Kidney Health and Disease","volume":"13 ","pages":"20543581261434815"},"PeriodicalIF":1.5,"publicationDate":"2026-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13065268/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147669992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Five Things to Know About Obesity in Kidney Transplant Candidates.","authors":"Somaya Zahran, Jason Y Lee, Sunita K S Singh","doi":"10.1177/20543581261434826","DOIUrl":"https://doi.org/10.1177/20543581261434826","url":null,"abstract":"","PeriodicalId":9426,"journal":{"name":"Canadian Journal of Kidney Health and Disease","volume":"13 ","pages":"20543581261434826"},"PeriodicalIF":1.5,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13053958/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147637568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acceptability of and Barriers to Continuous Glucose Monitoring in Individuals with Type 2 Diabetes Mellitus Receiving Chronic Hemodialysis: Research Letter.","authors":"Brigitte H Baragar, Ashley K Seitz, Carmen A Hurd, Clara J Bohm","doi":"10.1177/20543581251414602","DOIUrl":"https://doi.org/10.1177/20543581251414602","url":null,"abstract":"<p><p>Continuous glucose monitoring (CGM) in individuals receiving hemodialysis is more accurate than hemoglobin A1c (HbA1c) and may improve diabetes management in this population, but little is known regarding patient perspectives on CGM technology and its use in clinical outpatient hemodialysis care. We aimed to explore the real-world acceptability of CGM use in nonhospitalized individuals receiving hemodialysis. This pragmatic prospective observational study was nested within a qualitative improvement initiative that embedded an endocrinologist providing care for people with type 2 diabetes mellitus and HbA1c greater than 8% within the hemodialysis unit. As part of this initiative, some people seen by the endocrinologist were prescribed CGMs. These individuals were approached to participate in the study and followed for 2 weeks during CGM wear. Reasons for CGM decline were collected and collated inductively using content analysis. Of 47 consults, only 22 (47%) people were prescribed CGM. Of these, six (27%) declined CGM use and only six (27%) consented to the study, but ultimately only three participants (13.6%) completed the study. Reasons for CGM decline included lack of comfort with technology, cost and poor cellphone, internet and data availability. Our findings suggest that further exploration of barriers to CGM use and solutions to these barriers is required prior to broad use of CGM in real-world outpatient hemodialysis settings.</p>","PeriodicalId":9426,"journal":{"name":"Canadian Journal of Kidney Health and Disease","volume":"13 ","pages":"20543581251414602"},"PeriodicalIF":1.5,"publicationDate":"2026-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13039640/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147608312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of COVID-19 on Recipients of Solid Organ Transplants: A Cohort Study of In-Hospital Outcomes From the Canadian Organ Replacement Register.","authors":"Jacob B Michaud, Michael Manno, Katrina Sullivan, Nicole de Guia, Frank Ivis, Jagbir Gill, Annie-Claire Nadeau-Fredette, Louise Moist, S Joseph Kim, Allison Dart, Karthik K Tennankore","doi":"10.1177/20543581261434139","DOIUrl":"https://doi.org/10.1177/20543581261434139","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Solid organ transplant (SOT) recipients in Canada are particularly vulnerable to adverse hospital outcomes, especially during admissions involving a COVID-19 diagnosis. Limited evidence exists regarding how risks vary across different organ types and the extent to which a COVID-19 diagnosis influences hospital outcomes. This study aims to examine the association of organ subtypes on hospital morbidity and mortality, both in the presence and absence of a COVID-19 diagnosis in a large, nationally representative Canadian cohort.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;We used data from the Canadian Organ Replacement Register and the Discharge Abstract Database to examine hospitalization rates and in-hospital outcomes among all available adult SOT recipients with functioning grafts in Canada (excluding Quebec and Manitoba) from January 2021 to December 2022. In-hospital outcomes included transfer to a special care unit (SCU) and hospital mortality. Comparisons between organ subtypes (kidney, liver, heart, lung, and other/multi-organ) were conducted separately for admissions with and without a diagnosis of COVID-19, using kidney transplant (KT) recipients as the reference group. We included all admissions with a COVID-19 diagnosis irrespective of whether it was the primary reason for admission or not. Rates of hospitalization, SCU transfer, and mortality were analyzed using negative binomial or Poisson regression models (adjusted for age and sex) and reported using incidence rate ratios (IRRs) with 95% confidence intervals (CIs).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Among 23 497 SOT recipients, the majority (14 628, 62%) were KT recipients. Within this cohort, 2428 individuals (10.3%) experienced a total of 2925 hospitalizations with a COVID-19 diagnosis. In comparison, 7808 (33.2%) individuals experienced 17 656 hospitalizations without a COVID-19 diagnosis. Lung transplant recipients were more likely to be hospitalized (IRR = 1.65, 95% confidence interval CI: 1.52-1.80) and die in hospital (IRR = 1.2, 95% CI: 1.05-1.34) than KT recipients during admissions involving a COVID-19 diagnosis. In contrast, heart and liver transplant recipients were less likely to be hospitalized or experience a poor outcome. For hospitalizations without a COVID-19 diagnosis, lung and other/multi-organ transplant recipients were more likely than KT recipients to be hospitalized (IRR = 1.94, 95% CI: 1.76-2.15; IRR = 1.81, 95% CI: 1.45-2.26, respectively), transferred to an SCU (IRR = 1.89, 95% CI: 1.58-2.27; IRR = 1.81, 95% CI: 1.45-2.26, respectively), and die in hospital (IRR = 2.04, 95% CI: 1.84-2.27; IRR = 1.57, 95% CI: 1.33-1.85; respectively).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;SOT recipients in Canada, especially lung transplant recipients, experience high rates of hospitalization, SCU admission, and in-hospital mortality. Notable differences observed between organ subtypes for admissions with and without a COVID-19 diagnosis may reflect difference","PeriodicalId":9426,"journal":{"name":"Canadian Journal of Kidney Health and Disease","volume":"13 ","pages":"20543581261434139"},"PeriodicalIF":1.5,"publicationDate":"2026-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13036344/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147590206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sexual and Gender Minorities in Organ and Tissue Donation and Transplantation (OTDT): A Survey of Canadian OTDT Health Care Workers.","authors":"Murdoch Leeies, Carmen Hrymak, Owen Mooney, Gloria Vazquez-Grande, Tricia Carta, Julie Ho, Emily Christie, Karen Doucette, Jennifer Chandler, Stephen Brodovsky, Sonny Dhanani, Matthew J Weiss, Mark Gentile, Ken Sutha, Tzu-Hao Lee, David Collister","doi":"10.1177/20543581251412804","DOIUrl":"10.1177/20543581251412804","url":null,"abstract":"<p><strong>Purpose: </strong>Sexual and gender minorities (SGMs) experience inequities and harms in organ and tissue donation and transplantation (OTDT) systems. We surveyed OTDT health care workers (HCWs) to measure relevant self-reported practices, characterize opinions on potential equitable policy alternatives, and understand current capacities to provide SGM-specific care.</p><p><strong>Methods: </strong>We conducted a cross-sectional survey of Canadian OTDT HCWs (August to October 2024). Descriptive data are presented as counts and proportions. Sub-groups included organ donation, transplantation, and eye/tissue program respondents.</p><p><strong>Results: </strong>Of 600 eligible respondents, we analyzed responses from 123 (21%) completed surveys. Respondents were mainly coordinators (61%) and physicians (25%). Most respondents felt that the Health Canada policy that considers men who have sex with men (MSM) in the past 12 months at increased risk of transmitting human immunodeficiency virus (HIV) through donation and prohibits all tissue and organ donation except through an exceptional distribution process as discriminatory (97%, n = 119/123). Most respondents felt that gender-neutral, behavior-focused donor eligibility assessments would confer low or no risk for donor-derived infections in transplant recipients (77%, n = 95/123). Respondents had varied opinions on how HIV pre-exposure prophylaxis (PrEP) should influence donor risk assessments. Few respondents reported receiving any targeted training specific to cultural humility in the care of Two-Spirit, Lesbian, Gay, Bisexual, Transgender, Queer and more (2SLGBTQ+) patients in the organ or tissue donation system (11%, n = 14/123).</p><p><strong>Conclusions: </strong>Most respondents found current SGM-relevant OTDT policies to be unnecessarily discriminatory against SGMs and non-evidence-based, and they supported equitable policy revision. Respondents favor gender-neutral donor risk assessments that focus on behaviors specifically associated with an increased likelihood of HIV acquisition.</p>","PeriodicalId":9426,"journal":{"name":"Canadian Journal of Kidney Health and Disease","volume":"13 ","pages":"20543581251412804"},"PeriodicalIF":1.5,"publicationDate":"2026-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13033071/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147580718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}