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Corrigendum to "Prone Positioning as a Bridge to Recovery From Refractory Hypoxemia After Oversized Lung Transplant" [Transplantation Proceedings, 53/1 2021: 273-275]. 俯卧位作为超大肺移植术后难治性低氧血症恢复的桥梁 "的更正 [Transplantation Proceedings, 53/1 2021: 273-275]。
Transplantation proceedings Pub Date : 2024-11-01 Epub Date: 2024-06-08 DOI: 10.1016/j.transproceed.2024.01.001
Taehwa Kim, Hye Ju Yeo, Bong Soo Son, Dohyung Kim, Woo Hyun Cho, Hee Yun Seol
{"title":"Corrigendum to \"Prone Positioning as a Bridge to Recovery From Refractory Hypoxemia After Oversized Lung Transplant\" [Transplantation Proceedings, 53/1 2021: 273-275].","authors":"Taehwa Kim, Hye Ju Yeo, Bong Soo Son, Dohyung Kim, Woo Hyun Cho, Hee Yun Seol","doi":"10.1016/j.transproceed.2024.01.001","DOIUrl":"10.1016/j.transproceed.2024.01.001","url":null,"abstract":"","PeriodicalId":94258,"journal":{"name":"Transplantation proceedings","volume":" ","pages":"2106"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141294065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The TEG 6s Global Hemostasis System is Useful for Coagulation Management in Simultaneous Pancreas and Kidney Transplantation: The First Two Cases. TEG 6s 全局止血系统有助于同时进行胰腺和肾脏移植时的凝血管理:最初的两个病例
Transplantation proceedings Pub Date : 2024-11-01 Epub Date: 2024-10-26 DOI: 10.1016/j.transproceed.2024.10.017
Muneyuki Matsumura, Kengo Sasaki, Kazuaki Tokodai, Atsushi Fujio, Hiroyuki Ogasawara, Yoshihiro Shono, Michiaki Unno, Takashi Kamei
{"title":"The TEG 6s Global Hemostasis System is Useful for Coagulation Management in Simultaneous Pancreas and Kidney Transplantation: The First Two Cases.","authors":"Muneyuki Matsumura, Kengo Sasaki, Kazuaki Tokodai, Atsushi Fujio, Hiroyuki Ogasawara, Yoshihiro Shono, Michiaki Unno, Takashi Kamei","doi":"10.1016/j.transproceed.2024.10.017","DOIUrl":"10.1016/j.transproceed.2024.10.017","url":null,"abstract":"<p><strong>Introduction: </strong>Hypercoagulability-related graft thrombosis is the leading cause of graft failure after simultaneous pancreas-kidney transplantation (SPK). Addressing this issue is crucial to improve the outcomes of SPK recipients. Thromboelastography (TEG) has been used to assess the coagulation profiles of SPK recipients. Recently, a new-generation TEG device, the TEG 6s Global Hemostasis System, was introduced. This device offers advantages over TEG 5000, including less frequent calibration requirements, ease of use, and reduced sensitivity to movement. We hypothesized that TEG 6s would enhance coagulation management in SPK.</p><p><strong>Methods: </strong>We report two cases of Asian female SPK recipients in whom TEG 6s was used to assess coagulation status at six preset times during and after surgery.</p><p><strong>Results: </strong>Preoperatively, both patients exhibited hypercoagulability on TEG 6s. Postoperative intravenous heparin was administered, and the dose was titrated based on the TEG 6s results. Vascular thrombosis was not observed in either patient. Detailed TEG 6s and standard laboratory test results are reported. This pilot study demonstrates that TEG 6s monitoring can effectively assess coagulation status in SPK recipients, aiding in optimal coagulation management and reducing the risk of thrombotic complications leading to graft loss. The TEG 6s facilitated real-time and accurate coagulation assessment, allowing for tailored anticoagulant therapy.</p><p><strong>Conclusions: </strong>This is the first observational study to use TEG 6s in SPK recipients, indicating its potential benefits in improving patient outcomes. Further studies with larger sample sizes are warranted to validate these findings and establish comprehensive guidelines for using TEG 6s in SPK procedures.</p>","PeriodicalId":94258,"journal":{"name":"Transplantation proceedings","volume":" ","pages":"2021-2026"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142570849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endovascular Management of Thrombosed Cavoportal Anastomosis After Liver Transplantation Using Catheter Directed Thrombolysis and Stent Placement: A Case Report. 肝移植后腔静脉吻合口血栓形成的血管内治疗--导管引导溶栓和支架植入:病例报告。
Transplantation proceedings Pub Date : 2024-11-01 Epub Date: 2024-10-22 DOI: 10.1016/j.transproceed.2024.10.021
Lawrence Bonne, Hannah Van Malenstein, Peter Verhamme, Diethard Monbaliu, Chris Verslype, Mauricio Sainz Barriga, Schalk Van der Merwe, Thomas Vanassche, Jacques Pirenne, Geert Maleux
{"title":"Endovascular Management of Thrombosed Cavoportal Anastomosis After Liver Transplantation Using Catheter Directed Thrombolysis and Stent Placement: A Case Report.","authors":"Lawrence Bonne, Hannah Van Malenstein, Peter Verhamme, Diethard Monbaliu, Chris Verslype, Mauricio Sainz Barriga, Schalk Van der Merwe, Thomas Vanassche, Jacques Pirenne, Geert Maleux","doi":"10.1016/j.transproceed.2024.10.021","DOIUrl":"10.1016/j.transproceed.2024.10.021","url":null,"abstract":"<p><p>Cavoportal hemitransposition (CPHT) is a rarely performed treatment technique in liver transplantation in cases of extensive splanchnic thrombosis, in which the inferior vena cava of the recipient is used to perfuse the portal vein of the allograft. A case of a 65-year-old liver transplantation patient with an acutely thrombosed cavoportal anastomosis is presented. After unsuccessful medical treatment, recanalization was obtained with transfemoral catheter directed thrombolysis, angioplasty and stent placement. Although this type of treatment has been extensively documented for the management of portal anastomotic problems after orthotopic liver transplantation, data on its application in modified transplantation techniques including CPHT are rare. This technique provides a minimally invasive treatment option in CPHT patients with cavoportal anastomotic problems, who might otherwise require complex surgical repair or retransplantation.</p>","PeriodicalId":94258,"journal":{"name":"Transplantation proceedings","volume":" ","pages":"2072-2074"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142515702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long-Term Remission With Allo-HSCT for t(1;8)(q25;p11) Translocation: A Rare Case Report and Literature Review. 因t(1;8)(q25;p11)易位而接受异体造血干细胞移植的长期缓解:罕见病例报告和文献综述。
Transplantation proceedings Pub Date : 2024-11-01 Epub Date: 2024-10-29 DOI: 10.1016/j.transproceed.2024.10.018
Li Huang, Xiangjun Fu, Dan Liu, Li Guo, Li-E Lin
{"title":"Long-Term Remission With Allo-HSCT for t(1;8)(q25;p11) Translocation: A Rare Case Report and Literature Review.","authors":"Li Huang, Xiangjun Fu, Dan Liu, Li Guo, Li-E Lin","doi":"10.1016/j.transproceed.2024.10.018","DOIUrl":"10.1016/j.transproceed.2024.10.018","url":null,"abstract":"<p><strong>Background: </strong>The 8p11 myeloproliferative syndrome (EMS), a rare disorder characterized by translocations and interchanges at chromosome 8p11, is usually refractory to chemotherapy, and allogeneic hematopoietic stem cell transplantation (allo-HSCT) is currently the only promising treatment for long-term remission. Among 14 translocation partners associated with EMS, t(1;8)(q25;p11) are very uncommon, with only four cases previously reported in peer-reviewed journals in English.</p><p><strong>Case presentation: </strong>Here we report a 43-year-old man who presented with atypical peripheral T-cell lymphomas. Translocations between chromosomes 1q25 and 8p11 were detected during a bone marrow karyotype examination of 20 metaphases, and fluorescence in situ hybridization (FISH) revealed a positive rearrangement for the FGFR1 locus, confirming the diagnosis of EMS with t(1;8)(q25;p11). Despite rapid disease progression, he maintained remission for 27 months after admission due to aggressive chemotherapy combined with early allogeneic peripheral blood stem cell transplantation. We also conducted a literature review for 12 EMS patients treated with allo-HSCT who had rare karyotypes to better understand their clinicopathologic features and disease management.</p><p><strong>Conclusion: </strong>we report the first case of EMS with t(1;8)(q25;p11) to have a favorable outcome after allo-HSCT. The encouraging results support the use of aggressive chemotherapy in conjunction with early allo-HSCT for EMS patients with t(1;8)(q25;p11).</p>","PeriodicalId":94258,"journal":{"name":"Transplantation proceedings","volume":" ","pages":"2100-2105"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142549918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Post-Transplant Lymphoproliferative Disorder Presenting as a Gastrointestinal Fistulous Tract in a Heart Transplant Recipient: Case Report and Literature Review. 一名心脏移植受者移植后出现胃肠道瘘管的淋巴组织增生性疾病:病例报告和文献综述。
Transplantation proceedings Pub Date : 2024-11-01 Epub Date: 2024-08-30 DOI: 10.1016/j.transproceed.2024.07.008
Nour Hasan, Ramia Zakhour, Luz Helena Gutierrez Sanchez, Audrey R Lloyd, Geling Li, Clara L Ortiz, Cecelia Hutto
{"title":"Post-Transplant Lymphoproliferative Disorder Presenting as a Gastrointestinal Fistulous Tract in a Heart Transplant Recipient: Case Report and Literature Review.","authors":"Nour Hasan, Ramia Zakhour, Luz Helena Gutierrez Sanchez, Audrey R Lloyd, Geling Li, Clara L Ortiz, Cecelia Hutto","doi":"10.1016/j.transproceed.2024.07.008","DOIUrl":"10.1016/j.transproceed.2024.07.008","url":null,"abstract":"<p><p>We present a challenging case of Epstein-Barr virus-related isolated small bowel post-transplant lymphoproliferative disorder (PTLD) in a pediatric heart transplant recipient presenting as recurrent gastrointestinal (GI) bleeding and subsequently a GI fistulous tract with associated intra-abdominal abscess. Diagnosis was not confirmed until exploratory laparoscopy was performed, with excision of the fistulous tract revealing evidence of PTLD on pathology. Early diagnosis of GI-PTLD remains a challenge, especially if isolated in the small intestine. Diagnosis may rely on positron emission tomography/ computed tomography scan (PET/CT) or invasive intervention to obtain appropriate tissue samples for pathology diagnosis.</p>","PeriodicalId":94258,"journal":{"name":"Transplantation proceedings","volume":" ","pages":"2084-2091"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142116726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Long-Term Atorvastatin Therapy on the Development of Chronic Lung Allograft Dysfunction in Patients with Azithromycin Prophylaxis after Lung Transplantation. 长期阿托伐他汀治疗对肺移植术后阿奇霉素预防患者慢性肺移植功能障碍发展的影响
Transplantation proceedings Pub Date : 2024-11-01 Epub Date: 2024-10-24 DOI: 10.1016/j.transproceed.2024.10.015
Dan Zhang, Xiaoxing Wang, Wenwen Du, Pengmei Li
{"title":"Impact of Long-Term Atorvastatin Therapy on the Development of Chronic Lung Allograft Dysfunction in Patients with Azithromycin Prophylaxis after Lung Transplantation.","authors":"Dan Zhang, Xiaoxing Wang, Wenwen Du, Pengmei Li","doi":"10.1016/j.transproceed.2024.10.015","DOIUrl":"10.1016/j.transproceed.2024.10.015","url":null,"abstract":"<p><strong>Objective: </strong>To assess the impact of long-term atorvastatin (ATO) therapy on reducing recipient inflammation and immune response, thus lowering the risk of chronic lung allograft dysfunction (CLAD) in lung transplant recipients. This study aimed to investigate the effects of ATO on overall survival, lung function recovery, and its influence on inflammatory factors alongside azithromycin (AZI) prophylaxis.</p><p><strong>Methods: </strong>This retrospective single-center study included lung transplant recipients from January 2017 to December 2022. Patients who survival >1 year after lung transplantation and who were receiving AZI prophylaxis for >6 months were selected. Outcome measures involved pulmonary function assessments at various time points after AZI treatment, complete blood cell analysis, and inflammatory factor evaluations.</p><p><strong>Results: </strong>The incidence of CLAD was significantly lower in the long-term ATO group compared with those not on ATO (P = .011). Long-term ATO treatment significantly delayed CLAD onset after lung transplantation (850 days vs. 630 days; P = .041), with patients showing notably enhanced lung function recovery within 6 months of AZI therapy compared with the non-ATO group. Neutrophil levels decreased in patients with CLAD, and interleukin-6 concentrations significantly decreased in the AZI + ATO group compared with the AZI group. Overall patient survival was significantly better in the AZI+ATO group than in the AZI group (P = .02).</p><p><strong>Conclusion: </strong>In cases where CLAD develops despite AZI prophylaxis, long-term ATO treatment may lead to short-term improvements in lung function. It could also decrease inflammation levels in lung transplant recipients and enhance overall survival. The combination of AZI and long-term ATO therapy may be beneficial for CLAD prevention.</p>","PeriodicalId":94258,"journal":{"name":"Transplantation proceedings","volume":" ","pages":"2012-2020"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142515703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Remote Kidney and Liver Injury After Transplantation of Lung Allografts in an Allogeneic Mouse Model. 同种异体小鼠模型肺异体移植物移植后的远端肾脏和肝脏损伤
Transplantation proceedings Pub Date : 2024-11-01 Epub Date: 2024-10-24 DOI: 10.1016/j.transproceed.2024.10.020
Marcin L Sander, Volker Eulenburg, Tatsuo Maeyashiki, Jae-Hwi Jang, Sarah D Müller, Sebastian N Stehr, Wolfgang Jungraithmayr, Tobias Piegeler
{"title":"Remote Kidney and Liver Injury After Transplantation of Lung Allografts in an Allogeneic Mouse Model.","authors":"Marcin L Sander, Volker Eulenburg, Tatsuo Maeyashiki, Jae-Hwi Jang, Sarah D Müller, Sebastian N Stehr, Wolfgang Jungraithmayr, Tobias Piegeler","doi":"10.1016/j.transproceed.2024.10.020","DOIUrl":"10.1016/j.transproceed.2024.10.020","url":null,"abstract":"<p><strong>Background: </strong>Remote organ dysfunction is common after lung transplantation and might negatively affect the outcome. The local anesthetic ropivacaine was previously demonstrated to attenuate acute rejection after allogeneic lung transplantation in mice. We hypothesized that lung transplantation might result in detectable molecular signs of injury in kidneys and liver and that ropivacaine might attenuate this damage.</p><p><strong>Methods: </strong>Organs from C57BL/6 mice undergoing allogeneic orthotopic single-lung transplantation were procured at postoperative day 5 and analyzed using Western blot and real-time quantitative polymerase chain reaction probing for Src protein tyrosine kinase, STAT3, and bax/bcl-2. During cold ischemia, the allograft had either been flushed with normal saline only or in combination with ropivacaine (1 µM). A nontransplanted group of animals served as the baseline controls.</p><p><strong>Results: </strong>The allogeneic stimulus induced by transplantation led to an increase in Src-phosphorylation and STAT3-expression in the kidneys and livers of lung-transplanted mice compared to nontransplanted animals. Bax/bcl-2 as a marker of cellular apoptosis was not affected by the transplantation. In contrast to the findings in the transplanted lungs, the addition of ropivacaine did not have an effect on the examined markers of inflammation in the remote organs.</p><p><strong>Conclusions: </strong>The observed increase in the inflammatory signaling provides first insight into a possible mechanism, by which remote organ dysfunction after lung transplantation might occur.</p>","PeriodicalId":94258,"journal":{"name":"Transplantation proceedings","volume":" ","pages":"2046-2053"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142515706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Robot-Assisted Partial Nephrectomy for Multiple Allograft Renal Cell Carcinomas: A Case Report. 机器人辅助肾部分切除术治疗多发性同种异体肾细胞癌:病例报告。
Transplantation proceedings Pub Date : 2024-11-01 Epub Date: 2024-10-28 DOI: 10.1016/j.transproceed.2024.08.045
Ayane Tachiki, Kazuhiko Yoshida, Yuki Kobari, Shinsuke Mizoguchi, Ryo Minoda, Hironori Fukuda, Kouhei Unagami, Junpei Iizuka, Hideki Ishida, Toshio Takagi
{"title":"Robot-Assisted Partial Nephrectomy for Multiple Allograft Renal Cell Carcinomas: A Case Report.","authors":"Ayane Tachiki, Kazuhiko Yoshida, Yuki Kobari, Shinsuke Mizoguchi, Ryo Minoda, Hironori Fukuda, Kouhei Unagami, Junpei Iizuka, Hideki Ishida, Toshio Takagi","doi":"10.1016/j.transproceed.2024.08.045","DOIUrl":"10.1016/j.transproceed.2024.08.045","url":null,"abstract":"<p><strong>Background: </strong>Partial nephrectomy (PN) is strongly recommended as nephron-sparing surgery for T1 renal tumors. Although there have been some reports of robot-assisted PN (RAPN) for solitary allograft renal tumors, only a few cases of RAPN for multifocal allograft renal tumors have been reported. Herein, we report a case of a patient who underwent RAPN for multifocal allograft renal cell carcinoma (RCCs).</p><p><strong>Case presentation: </strong>A 77-year-old male was diagnosed with 24- and 15-mm lesions in the middle portion of a right iliac fossa renal allograft. RAPN was performed using a transperitoneal approach 22 years after the kidney transplantation. The allograft renal artery was clamped, and the tumors were resected. Pathological examination revealed clear-cell RCC with negative surgical margins. There were no perioperative complications, and kidney function did not significantly change during surgery.</p><p><strong>Conclusion: </strong>RAPN is a feasible and effective treatment option for multiple allograft RCCs. The successful preservation of renal function coupled with minimal perioperative complications underscores the potential of RAPN. Our observations suggest that RAPN can be safely implemented in similar high-risk cases, offering a nephron-sparing alternative that might extend quality of life and reduce the need for dialysis in transplant recipients.</p>","PeriodicalId":94258,"journal":{"name":"Transplantation proceedings","volume":" ","pages":"2063-2067"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142570833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effects of Volatile Anesthetics on Early Clinical Outcomes in Liver Transplantation: A Systematic Review and Meta-Analysis. 挥发性麻醉剂对肝移植早期临床结果的影响:系统回顾与元分析》。
Transplantation proceedings Pub Date : 2024-11-01 Epub Date: 2024-10-29 DOI: 10.1016/j.transproceed.2024.09.003
Insun Park, Eun-Ki Min, Jae Hyon Park, Ah-Young Oh, Jung-Hee Ryu
{"title":"The Effects of Volatile Anesthetics on Early Clinical Outcomes in Liver Transplantation: A Systematic Review and Meta-Analysis.","authors":"Insun Park, Eun-Ki Min, Jae Hyon Park, Ah-Young Oh, Jung-Hee Ryu","doi":"10.1016/j.transproceed.2024.09.003","DOIUrl":"10.1016/j.transproceed.2024.09.003","url":null,"abstract":"<p><strong>Background: </strong>The aim of this systematic review and meta-analysis was to evaluate the effects of volatile anesthesia (VA) on early clinical outcomes in liver transplantation.</p><p><strong>Methods: </strong>We searched electronic databases to identify relevant studies comparing VA to non-VA in liver transplant recipients. The primary outcome assessed was early allograft dysfunction (EAD), and secondary outcomes were postoperative peak liver function tests (LFT) including aspartate transaminase (AST) and alanine transaminase (ALT) levels, and hospitalization time.</p><p><strong>Results: </strong>Six relevant studies involving 919 patients were analyzed. In meta-analysis of prospective studies, VA was associated with fewer incidence of EAD than non-VA (RR: 0.45; 95% CI: 0.25, 0.84; P = .012; I<sup>2</sup> = 0%; P<sub>h</sub> = 0.334) but this association was not significant in meta-analysis of retrospective studies (OR: 0.83; 95% CI: 0.58, 1.19; P = .310; I<sup>2</sup> = 0%; P<sub>h</sub> = 0.624). No significant difference in peak AST (SMD: -0.14 U/L; 95% CI: -0.65, 0.37 U/L; P = .594; I<sup>2</sup> = 69.9%; P<sub>h</sub> = 0.036) and ALT (SMD: -0.16 U/L; 95% CI: -0.65, 0.33 U/L; P = .529; I<sup>2</sup> = 67.0%; P<sub>h</sub> = 0.048) were found between VA and non-VA. The hospitalization time also did not differ between the two groups (SMD: -0.09 days; 95% CI: -0.29, 0.10 days; P = .350; I<sup>2</sup> = 0%; P<sub>h</sub> = 0.864).</p><p><strong>Conclusions: </strong>While there is potential protective effect of VA against EAD in liver transplant recipients, certainty remains low, whereas VA was not associated with postoperative LFT or hospitalization time.</p>","PeriodicalId":94258,"journal":{"name":"Transplantation proceedings","volume":" ","pages":"1984-1994"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142549923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effects of Two Kinds of Gargles on Oral Mucositis in Patients After Allogeneic Stem Cell Transplantation. 两种漱口水对异体干细胞移植后患者口腔黏膜炎的影响
Transplantation proceedings Pub Date : 2024-11-01 Epub Date: 2024-10-29 DOI: 10.1016/j.transproceed.2024.10.023
Wei Hu, Hua Jiang, Ting Wang, Xiu-Juan Guo, Bei-Bei Zhang, Yan Song, Ce Shi, Xiao-Dong Xu, Lin-Nan Wang, Xin-Xin He, Bo-Ning Liu, Jun-Xiu Zhou, Ze-Yu Xue
{"title":"The Effects of Two Kinds of Gargles on Oral Mucositis in Patients After Allogeneic Stem Cell Transplantation.","authors":"Wei Hu, Hua Jiang, Ting Wang, Xiu-Juan Guo, Bei-Bei Zhang, Yan Song, Ce Shi, Xiao-Dong Xu, Lin-Nan Wang, Xin-Xin He, Bo-Ning Liu, Jun-Xiu Zhou, Ze-Yu Xue","doi":"10.1016/j.transproceed.2024.10.023","DOIUrl":"10.1016/j.transproceed.2024.10.023","url":null,"abstract":"<p><strong>Objective: </strong>The objective of this study was to compare the effects of two kinds of gargles (Koushu & Koutai) on oral mucositis (OM) in patients with agranulocytosis.</p><p><strong>Methods: </strong>One hundred eighty patients who underwent allogeneic hematopoietic stem cell transplantation in the Peking University Institute of Hematology were enrolled from March 2018 to January 2019. The subjects were randomly divided into two groups by random number table. The observation group gargled with Koushu gargle, whereas the control group gargled with Koutai gargle. Patients in both groups used 10 to 15 mL of gargles for 2 minutes when awake in the morning, 30 minutes after each meal, and before sleep. The two groups used the same way to gargle except the types of gargle used. The difference of incidence, grade, healing time, and pain grade of oral mucositis were analyzed.</p><p><strong>Results: </strong>The incidence of oral mucositis in the observation group was significantly lower than that in the control group (P < .01).There were no significant difference in grade of OM, healing time, or pain grade between the two groups (P > .05). The effect of the Koushu gargle on the prevention of OM among the patients with agranulocytosis is better than that of the Koutai gargle. The Koushu gargle is better suited than the Koutai gargle as a prevention and treatment option for the patients.</p>","PeriodicalId":94258,"journal":{"name":"Transplantation proceedings","volume":" ","pages":"2027-2031"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142549922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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