{"title":"Impact of Ultrasonographically Measured Elastography Scores on Renal Prognosis in Kidney Transplant Recipients.","authors":"Serap Yadigar, Pınar Özdemir, Erman Özdemir, Ömer Aydıner, Ayşegül Karadayı, Elif Arı Bakır","doi":"10.1016/j.transproceed.2025.01.009","DOIUrl":"https://doi.org/10.1016/j.transproceed.2025.01.009","url":null,"abstract":"<p><strong>Background: </strong>The aim of this study was to investigate the relationship between ultrasonographic elastography score and long-term renal prognosis in renal transplant patients.</p><p><strong>Methods: </strong>A retrospective cohort study of 100 patients who underwent renal transplantation in our hospital between 2005 and 2022 was performed. Patients were divided into two groups as those with elastography scores higher than 8.45 kPa (n = 50) and those with elastography scores equal to or lower than 8.45 kPa (n = 50). Elastography measurements were performed with Siemens Acuson S2000 ultrasound system and the scores were compared with renal function parameters and other clinical characteristics.</p><p><strong>Results: </strong>Patients with high elastography scores had smaller kidney size (P = .010), lower eGFR (P = .002), and higher proteinuria and albuminuria levels (P < .05) than patients with low elastography scores. There was a significant association between elastography score and the risk of renal dysfunction (OR = 1.039, P = .006).</p><p><strong>Conclusions: </strong>A large elastography score may act as a significant biomarker for prognosing the risk of renal dysfunction in subjects undergoing kidney transplantation. These findings suggest that elastography may become an invaluable noninvasive tool during the long-term follow-up of patients with renal transplants.</p>","PeriodicalId":94258,"journal":{"name":"Transplantation proceedings","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143639957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Preoperative Calcimimetic Treatment may Prevent Serum Creatinine Elevation after Parathyroidectomy in Kidney Transplant Recipients: A Retrospective Cohort Study.","authors":"Manabu Okada, Shunji Narumi, Tetsuhiko Sato, Tomoki Himeno, Yuki Hasegawa, Kenta Futamura, Takahisa Hiramitsu, Yuki Shimamoto, Yoshihiko Watarai, Toshihiro Ichimori","doi":"10.1016/j.transproceed.2025.03.001","DOIUrl":"https://doi.org/10.1016/j.transproceed.2025.03.001","url":null,"abstract":"<p><strong>Background: </strong>Hyperparathyroidism (HPT) often persists after successful kidney transplantation (KTx). Although parathyroidectomy (PTx) is an effective treatment option for post-KTx HPT, it is associated with postoperative elevation of serum creatinine levels. We hypothesized that pre-PTx calcimimetic treatment could alleviate the post-PTx increase in serum creatinine levels.</p><p><strong>Methods: </strong>This retrospective cohort study enrolled KTx patients who underwent initial PTx between 2004 and 2023. Patients' background characteristics and laboratory data were investigated. The primary outcome was a change in the estimated glomerular filtration rate (eGFR). The cohort was divided into 2 groups based on the presence of pre-PTx calcimimetic treatment. Multivariate linear regression analysis assessed the association between calcimimetic treatment and percent eGFR 1 week after PTx.</p><p><strong>Results: </strong>Of the 77 KTx patients who underwent PTx, 28 were treated with pre-PTx calcimimetics (calcimimetic group), and the others were not (noncalcimimetic group). Compared with the noncalcimimetic group, the calcimimetic group had lower serum calcium levels before PTx (10.3 vs 11.2 mg/dL, P < .001) and a significantly higher percentage of eGFR 1 week after PTx (95.1% vs 81.5%, P < .001). According to the multivariate analysis, pre-PTx calcimimetic treatment was positively associated with percent eGFR (regression coefficient estimate, 13.76; 95% confidence interval, 7.02-20.50; P < .001) 1 week after PTx.</p><p><strong>Conclusion: </strong>Pre-PTx calcimimetic treatment may prevent post-PTx elevation of serum creatinine levels in KTx patients.</p>","PeriodicalId":94258,"journal":{"name":"Transplantation proceedings","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143639958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Serologic Evaluation for Severe Acute Respiratory Syndrome Coronavirus 2 in Pediatric Heart Transplantation Recipients and Patients on a Pediatric Heart Transplantation Waiting List in a Quaternary Hospital.","authors":"Clarice Arruda Villari, Adailson Siqueira, Celia Strunz, Christiane Moscan, Marcelo Jatene, Nana Miura, Estela Azeka","doi":"10.1016/j.transproceed.2024.04.023","DOIUrl":"10.1016/j.transproceed.2024.04.023","url":null,"abstract":"<p><strong>Background: </strong>The Coronavirus disease 2019 (COVID-19) pandemic has been a global reality for longer than 3 years. Serologic studies have great importance for understanding the virus's behavior in populations, as it can suggest the status of the epidemic in a community. This cross-sectional study aimed to analyze the serologic profile for COVID-19 in patients before and after pediatric heart transplantation.</p><p><strong>Methods: </strong>Serology data on IgG and IgM antibodies for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were collected in patients of the Pediatric Cardiology and Congenital Heart Diseases unit of a Brazilian hospital between January and August 2022. A total of 174 patients were recruited, including 28 on the transplantation waiting list and 146 heart transplant recipients. Information for each patient, including demographics (age, sex, state of origin), type of heart disease (congenital or acquired), and time after transplantation, was analyzed.</p><p><strong>Results: </strong>Overall, 72 patients had a positive serology for anti-N antibodies (48.0%), including 62 heart transplant recipients and 10 patients on the transplantation waiting list, The positivity rates in these 2 groups were 48.1% and 47.6%, respectively. Positivity rates for previously infected individuals were 62.5% and 62.1%, respectively.</p><p><strong>Conclusions: </strong>Approximately one-half of our study sample had IgM or IgG antibodies against the SARS-CoV-2 virus. Serologic studies on the duration and level of protection provided by these antibodies are relevant public health tools for health promotion of vulnerable groups and can be useful for future studies on antibody behavior.</p>","PeriodicalId":94258,"journal":{"name":"Transplantation proceedings","volume":" ","pages":"1112-1114"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140961354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Transplantation proceedingsPub Date : 2024-06-01Epub Date: 2024-05-17DOI: 10.1016/j.transproceed.2024.04.016
Thamiris Quiqueto Marinelli, Heloisa Cristina Caldas, Maria Alice Sperto Ferreira-Baptista, Fernanda Salomão Gorayeb-Polacchini, Ana Carolina Brecher Souza, Ludimila Leite Marzochi, Guilherme Jairo Luiz da Silva, Ida Maria Maximina Fernandes-Charpiot, Mario Abbud-Filho
{"title":"Analysis of COVID-19 Infection in Kidney Transplant Recipients.","authors":"Thamiris Quiqueto Marinelli, Heloisa Cristina Caldas, Maria Alice Sperto Ferreira-Baptista, Fernanda Salomão Gorayeb-Polacchini, Ana Carolina Brecher Souza, Ludimila Leite Marzochi, Guilherme Jairo Luiz da Silva, Ida Maria Maximina Fernandes-Charpiot, Mario Abbud-Filho","doi":"10.1016/j.transproceed.2024.04.016","DOIUrl":"10.1016/j.transproceed.2024.04.016","url":null,"abstract":"<p><strong>Background: </strong>COVID-19, caused by SARS-CoV-2, was responsible for higher morbidity and mortality in renal transplant recipients (RTx). The objective of the study was to evaluate the impact of COVID-19 infection on RTx in a single center in Brazil.</p><p><strong>Methods: </strong>A cohort of 135 RTx was evaluated between December 2019 and June 202l, and demographics, clinical, and laboratory profiles were analyzed from deceased donors with COVID-19.</p><p><strong>Results: </strong>Diabetic and RTx from extended criterion donors presented more frequently the severe form of the disease. Serum creatinine (sCr) after 3 months of diagnosis of COVID-19 varied according to the severity of infection. The lethality rate was higher in the group with severe symptoms (65%) compared with those with mild infection (1.5%).</p><p><strong>Conclusion: </strong>The increase in sCr was associated with disease severity. The lethality rate for COVID-19 was 26.6%. These rates are 10-20 times higher than those reported in the general population and suggest that rigorous observation, early diagnosis, and disease prevention measures are crucial in RTx.</p>","PeriodicalId":94258,"journal":{"name":"Transplantation proceedings","volume":" ","pages":"1048-1051"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140961316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Karolina Baran, A. Furmańczyk-Zawiska, R. Wieczorek-Godlewska, Przemysław Nitek, Magdalena Durlik
{"title":"Pneumocystis jirovecii Pneumonia in a Liver Transplant Recipient With an Adverse Reaction to Trimethoprim/Sulfamethoxazole Treated With a Sulfonamide Desensitization Protocol: Case Report.","authors":"Karolina Baran, A. Furmańczyk-Zawiska, R. Wieczorek-Godlewska, Przemysław Nitek, Magdalena Durlik","doi":"10.1016/j.transproceed.2024.03.022","DOIUrl":"https://doi.org/10.1016/j.transproceed.2024.03.022","url":null,"abstract":"","PeriodicalId":94258,"journal":{"name":"Transplantation proceedings","volume":"284 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141028842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Transplantation proceedingsPub Date : 2024-05-01Epub Date: 2024-05-17DOI: 10.1016/j.transproceed.2024.03.027
Jarosław Czerwiński, Anna Pszenny, Krystyna Antoszkiewicz, Teresa Danek, Łukasz Górski, Małgorzata Hermanowicz, Anna Łęczycka, Piotr Malanowski, Adam Parulski, Łukasz Szemis, Jacek Ziaja, Artur Kamiński
{"title":"Current Data on Organ Donation and Transplantation in Poland: Poltransplant Activity 2017 to 2022.","authors":"Jarosław Czerwiński, Anna Pszenny, Krystyna Antoszkiewicz, Teresa Danek, Łukasz Górski, Małgorzata Hermanowicz, Anna Łęczycka, Piotr Malanowski, Adam Parulski, Łukasz Szemis, Jacek Ziaja, Artur Kamiński","doi":"10.1016/j.transproceed.2024.03.027","DOIUrl":"10.1016/j.transproceed.2024.03.027","url":null,"abstract":"<p><strong>Background: </strong>In this paper, we present organ donation and transplantation activities in Poland from 2017 to 2022. Data came from registries maintained by the Polish Transplant Coordinating Center Poltransplant and consisted of the national waiting list, deceased donor registry, transplant registry, and the live donor registry. Poltransplant is the Competent Authority in Organs, with tasks related to preparing assessments, analyses, information, and reports in transplantation medicine and publishing and disseminating these results in the country and abroad. Poltransplant edits the Poltransplant Bulletin on its web pages and presents its activities at Polish Transplantation Society congresses, published consecutively as professional papers.</p>","PeriodicalId":94258,"journal":{"name":"Transplantation proceedings","volume":" ","pages":"758-762"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140961346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"E. Solowiej, J. Solowiej, M. Godlewski, et al. Regarding the article \"Application of Sulforaphane: histopathological study of intraportal transplanted pancreatic islets into livers of diabetic rats,\" Transplant Proc (2006 Jan/Feb) 38(1): pages 282-283.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":94258,"journal":{"name":"Transplantation proceedings","volume":"41 5","pages":"2006"},"PeriodicalIF":0.0,"publicationDate":"2009-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141158735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}