Transplantation proceedings最新文献

{"title":"Predicting Postoperative Serum Creatinine Levels in Living Donor Kidney Transplantation: The Role of Donor-Recipient Muscle Mass Differences.","authors":"Ezgi Avanaz, Ali Avanaz","doi":"10.1016/j.transproceed.2025.05.001","DOIUrl":"https://doi.org/10.1016/j.transproceed.2025.05.001","url":null,"abstract":"<p><strong>Purpose: </strong>In living donor kidney transplantation (LDKT), postoperative serum creatinine (SCr) levels in the recipients are influenced by muscle mass, which can be assessed via psoas muscle area (PMA) measurements. This study aimed to create a formula to predict the postoperative SCr levels by evaluating the difference in muscle mass between donors and recipients.</p><p><strong>Methods: </strong>We retrospectively analyzed data from patients aged 18 years and older who underwent LDKT between January 2020 and December 2022. Recipients and donors with preoperative magnetic resonance imaging (MRI) or computed tomography (CT) scans were included in the PMA measurements. A total of 67 patients were analyzed.</p><p><strong>Results: </strong>The recipients had a mean age of 42 ± 12.8 years and a mean postoperative SCr of 1.24 ± 0.33 mg/dl. Multivariate analysis revealed that donor age and the difference in the PMA between recipients and donors were significant predictors of postoperative SCr levels. The derived formula is as follows: Recipient postoperative SCr = 0.320 + (0.016 × recipient-donor PMA difference/100) + (0.006 × donor age).</p><p><strong>Conclusion: </strong>This study highlights that considering the difference in muscle mass between donors and recipients can enhance the prediction of postoperative SCr levels. Further multicenter studies are needed to validate and refine this predictive model.</p>","PeriodicalId":94258,"journal":{"name":"Transplantation proceedings","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144228209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Disseminated Cunninghamella bertholletiae Infection From Latent Lower Limb Mass After Kidney Transplant: A Case Report.","authors":"Yadi Wang, Keqin Zhang, Ling Liu, Runtian Qu","doi":"10.1016/j.transproceed.2025.03.032","DOIUrl":"https://doi.org/10.1016/j.transproceed.2025.03.032","url":null,"abstract":"<p><strong>Background: </strong>Cunninghamella bertholletiae (C. bertholletiae), a rare yet highly virulent species within the Mucorales order, predominantly affects individuals with compromised immune systems. Disseminated infections caused by this pathogen frequently lead to severe complications, underscoring the necessity for prompt diagnosis and aggressive therapeutic interventions. Invasive fungal diseases (IFDs) continue to be a major cause of morbidity and mortality among kidney transplant recipients, characterized by elevated incidence and mortality rates. The early and precise identification of fungal pathogens is crucial for optimizing patient outcomes.</p><p><strong>Case presentation: </strong>This report presents a case study of a 37-year-old male kidney transplant recipient who developed a disseminated C. bertholletiae infection from a latent lower limb lesion. Initially, he showed symptoms of high fever and dyspnea, leading to diagnoses of sepsis, severe pneumonia, acute respiratory distress syndrome, and allograft dysfunction. After surgery, he had recurrent pleural effusion and worsening pulmonary nodules. Metagenomic next-generation sequencing (mNGS) confirmed C. bertholletiae infection, and histopathology revealed mucormycosis with vascular invasion, thrombosis, and tissue necrosis. The patient underwent a 13-month antifungal treatment with amphotericin B lipid complex, posaconazole, and isavuconazole.</p><p><strong>Conclusion: </strong>This case highlights the essential role of histopathology and mNGS in early detection of rare IFDs and stresses the need for a multidisciplinary approach combining surgery with antifungal therapy. The effective management of disseminated C. bertholletiae infection using a triple antifungal regimen offers important insights for future cases, underscoring the importance of early diagnosis and personalized treatment in immunocompromised patients.</p>","PeriodicalId":94258,"journal":{"name":"Transplantation proceedings","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144121917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Conundrum of Biventricular Takotsubo Syndrome After Heart Transplantation: A Case Report.","authors":"Simona Covino, Luigi Marotta, Fiorella Chiara Delle Femine, Diego D'Arienzo, Biagio Liccardo, Francesco Natale, Giovanni Cimmino, Enrica Pezzullo, Irene Mattucci, Adriano Caputo, Claudio Marra, Paolo Golino, Francesco Loffredo, Cristiano Amarelli","doi":"10.1016/j.transproceed.2025.03.019","DOIUrl":"https://doi.org/10.1016/j.transproceed.2025.03.019","url":null,"abstract":"<p><p>Takotsubo syndrome (TTS) is a rare cause of myocardial infarction in heart transplant patients. The heterogeneity of reported cases makes it impossible to identify specific characteristics of patients at risk. The occurrence of biventricular TTS is even less frequent its impact on long-term prognosis is unpredictable. We in here describe a rare case of biventricular TTS occurred in a woman 13 years after heart transplant.</p>","PeriodicalId":94258,"journal":{"name":"Transplantation proceedings","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144034727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Large-for-Size Graft in Cadaveric Liver Transplantation: Application of BSA (Body Surface Area) for Prompt Evaluation.","authors":"Yasuhiro Fujimoto, Norihiro Goshima, Yuki Masano, Nobuhiko Kurata, Yasuhiro Ogura","doi":"10.1016/j.transproceed.2025.03.024","DOIUrl":"https://doi.org/10.1016/j.transproceed.2025.03.024","url":null,"abstract":"<p><strong>Introduction: </strong>In recent years, with the increase in the number of brain-dead donors in Japan, brain-dead liver transplantation has been on the rise. In partial living donor liver transplantation, which accounts for the majority of liver transplants in Japan, small-for-size graft has been a problem in adult recipients, whereas large-for-size graft has not been a matter of debate. We experienced a case in which a large-for-size graft resulted in difficulty when closing the wound. With the increase in brain death transplantation, the exclusion of large-for-size grafts becomes an issue when selecting grafts.</p><p><strong>Methods: </strong>Retrospective chart review. At Nagoya University, 80 brain-dead liver transplants were performed between Feb. 2005 and Dec. 2023. Comparative evaluation of BSA (body surface area) and was performed on 72 patients, excluding 8 split liver transplants, based on the height and weight of the donor and recipient at the time of transplantation. The state of wound closure was also ascertained from the surgical records.</p><p><strong>Results: </strong>Seven cases out of 72 were considered \"large-for-size\" regarding BSA. Among them, 1 \"large-for-size\" patient had difficulty in closing the abdomen during the surgical procedure.</p><p><strong>Conclusions: </strong>Prompt screening for matching graft size and donor body size may be possible with BSA. The algorithm allows for rapid and efficient donor-recipient matching while reducing the reliance on advanced imaging in most cases.</p>","PeriodicalId":94258,"journal":{"name":"Transplantation proceedings","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144059302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Donor With Occult Breast Cancer: The Fate of Multiple Organ Recipients: A Case Report And Review of the Literature.","authors":"Hanna Storoniak, Alicja Dębska-Ślizień, Andrzej Chamienia, Anna Drobińska, Piotr Remiszewski, Elżbieta Senkus-Konefka, Jacek Wojarski, Sławomir Żegleń, Ewelina Serkies-Minuth, Katarzyna Michalska-Małecka, Tomasz Stefaniak, Rafał Pęksa, Wojciech Biernat, Maciej Wilczyński, Paulina Rościcka, Jarosław Kobiela, Aleksandra Zgryzniak","doi":"10.1016/j.transproceed.2025.04.009","DOIUrl":"https://doi.org/10.1016/j.transproceed.2025.04.009","url":null,"abstract":"<p><p>We present the outcomes of organ recipients from a 69-year-old female donor diagnosed with occult breast cancer. The donor had no relevant medical history nor aberrant finding or sings of malignancy at the time of organ procurement. The organ donation encompassed the right kidney, liver, lungs, and corneas, which were thereafter transplanted. The left kidney of the donor was not accepted due to macroscopic features of chronic injury. Routine histopathological examination disclosed microscopic metastasis of lobular breast carcinoma. Consequently, given the elevated risk of transmission, the following interventions were implemented: the kidney recipient underwent nephrectomy followed by the discontinuation of immunosuppression; the liver recipient was administered letrozole and subsequently underwent liver retransplantation 3 months later; the lung recipient received a therapeutic regimen consisting of goserelin and letrozole; and the cornea recipient received nonvascular tissues. At the most recent follow-up in October 2024 (13 months post-transplantation), all recipients were reported to be in good health and free from disease. This remarkable case underscores that even an exhaustive evaluation of the donor may not unveil the presence of malignancy. Appropriate logistical and therapeutic strategies are crucial in preventing the transmission of cancer. Although the risk of malignancy transmission remains low, it is still present, necessitating that patients remain under vigilant medical supervision.</p>","PeriodicalId":94258,"journal":{"name":"Transplantation proceedings","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144013939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge and Attitudes Toward Organ Donation Among Senior Medical and Nursing Students: Preliminary Findings of a Single-Center Study in Northern Italy.","authors":"Alessandra Agnese Grossi, Alberto Passi, Sergio Vesconi, Marina Morgutti, Mario Picozzi, Maria Assunta Donato, Federica De Min, Alessandro De Martino, Elisa Raimondo, Alessia Bresil, Martina Baiardo Redaelli, Luca Cabrini","doi":"10.1016/j.transproceed.2025.03.020","DOIUrl":"https://doi.org/10.1016/j.transproceed.2025.03.020","url":null,"abstract":"<p><strong>Introduction: </strong>University students' knowledge and attitudes toward organ donation (OD) remain poorly understood. Medical and nursing students, in particular, play a critical role as future healthcare professionals, serving as primary points of contact for citizens and potential donors' families and influencing their decisions. This study aims to identify gaps in their education and information to orient the development of targeted educational programs.</p><p><strong>Methods: </strong>An online anonymous survey was disseminated among final-year Medicine and Nursing students at a university in Northern Italy. The 39-item questionnaire, adapted from previous studies and refined by an expert panel, included questions to assess knowledge, attitudes, and intentions regarding OD. Two open-ended questions collected additional suggestions for targeted public awareness interventions.</p><p><strong>Results: </strong>Preliminary analyses (n = 65) indicate that most students possess basic knowledge of OD, but gaps remain, particularly concerning transplant procedures and the neurological criteria for determination of death. While 95.4% expressed favorable attitudes toward OD and 80% had formally expressed their intent-primarily during ID renewal (75.4%)-students highlighted the need for further education. Preferred methods included seminars (41.5%), integration into standard courses (36.9%), and elective modules (20%). Active student participation in public awareness campaigns was suggested to enhance understanding and engagement.</p><p><strong>Conclusions: </strong>Although students demonstrate a foundational understanding of OD, critical knowledge gaps persist. These findings underscore the need for targeted educational initiatives to better prepare future healthcare professionals. Strengthening their knowledge and skills is key to fostering an informed culture of OD and supporting the families of potential donors.</p>","PeriodicalId":94258,"journal":{"name":"Transplantation proceedings","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144048110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recommendations for Hepatic Artery Anastomosis in Liver Transplantation: A Group Experience.","authors":"Hüseyin Yönder, Faik Tatlı, Mehmet Sait Berhuni, Hasan Elkan, Mehmet Salih Aydın, Fırat Erkmen, Felat Çiftçi, Vedat Kaplan, Abdullah Özgönül, Mehmet Yılmaz","doi":"10.1016/j.transproceed.2025.03.007","DOIUrl":"https://doi.org/10.1016/j.transproceed.2025.03.007","url":null,"abstract":"<p><strong>Background: </strong>Hepatic artery thrombosis (HAT) is a severe complication following living-donor liver transplantation that can be fatal if revascularization is not achieved. This study aims to present the 8-year experience of the Organ Transplantation Clinic at Harran University Faculty of Medicine.</p><p><strong>Methods: </strong>From 2014 to 2021, a total of 56 patients, comprising 35 men (62.5%) and 21 women (37.5%), who underwent either living-donor or cadaveric liver transplantation were included in the study. In cadaveric recipients, a continuous suture technique with 7/0 polypropylene was used, and in living-donor graft recipients, an interrupted suture technique with 7/0 polypropylene was performed in anastomosis. All patients received an intraoperative dose of 2500 to 5000 units (60 U/kg) of heparin prior to anastomosis. Doppler ultrasound was performed on all patients following the anastomosis.</p><p><strong>Results: </strong>Three out of the 56 patients (5.35%) developed HAT on postoperative day 1. One of these patients underwent hepatic artery revision on postoperative day 1, with no subsequent rethrombosis. The second patient underwent retransplantation on postoperative day 1. However, this patient could not tolerate the reoperation and passed away on the second day after transplantation. The last patient underwent endovascular stenting on postoperative day 1. However, this patient experienced rethrombosis on the first day after the procedure and rapidly deteriorated hemodynamically, which proved fatal.</p><p><strong>Conclusions: </strong>HAT directly affects postoperative patient morbidity and mortality. The outcomes are favorable when hepatic artery anastomosis is performed using 7/0 polypropylene, with a continuous suture technique for cadaveric cases and an interrupted suture technique for living-donor cases, and is carried out by experienced hands.</p>","PeriodicalId":94258,"journal":{"name":"Transplantation proceedings","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144053811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"De-Novo Hepatic Angiosarcoma in a Liver Transplant Recipient.","authors":"Alp Serhat Kahveci, Aysha Aslam, Yiqin Xiong, Tomohiro Tanaka","doi":"10.1016/j.transproceed.2025.03.031","DOIUrl":"https://doi.org/10.1016/j.transproceed.2025.03.031","url":null,"abstract":"<p><p>Angiosarcoma (AS) is a rare and highly aggressive soft tissue tumor. Cases of de-novo hepatic angiosarcoma after liver transplantation have not been described in the literature. Here, we present an exceedingly rare case of hepatic AS developing in a patient with a liver transplant (LT). A 72-year-old male with a history of orthotopic LT presented with cholestatic pattern of liver enzyme elevation for 3 months. Six years prior, he had undergone LT for treatment of alcohol-associated cirrhosis. He was on everolimus (1 mg twice daily) and low-dose tacrolimus (0.5 mg twice daily) for immunosuppression without evidence of allograft rejection. At presentation, his ALP and GGT were elevated to 1-2 times the upper limit of normal. He endorsed a 20-pound weight loss, anorexia, abdominal pain, and distention. A right upper quadrant ultrasound with doppler revealed a 14 cm liver mass and moderate ascites. This was followed by a multiphasic abdominal MRI, which revealed a 14.9 cm central hepatic mass involving the right and left hepatic lobes with extension into the hepatic veins and the inferior vena cava. The patient underwent a core biopsy of the tumor, which was suggestive of high-grade liver AS. A follow-up PET/CT scan was concerning for right adrenal gland and bilateral pulmonary metastasis. Patient was discussed at multidisciplinary tumor board and started on palliative chemotherapy with a single agent (docetaxel). Due to medication intolerance, patient discontinued the regimen after 1 cycle, and opted to transition to comfort care. He passed away 3 months after initial diagnosis.</p>","PeriodicalId":94258,"journal":{"name":"Transplantation proceedings","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144049511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Living Donor Liver Transplantation for Iatrogenic Vascular Injury During Laparoscopic Cholecystectomy: Case Report.","authors":"Adem Tuncer, Canan Dilay Dirican, Emrah Sahin, Veysel Ersan, Bulent Unal, Abuzer Dirican","doi":"10.1016/j.transproceed.2025.02.039","DOIUrl":"https://doi.org/10.1016/j.transproceed.2025.02.039","url":null,"abstract":"<p><p>Acute liver failure (ALF) caused by hepatic vascular injury during cholecystectomy is a rare but serious indication of liver transplantation (LT). We present a case of acute liver failure secondary to portal vein, hepatic artery, and common bile duct injury during laparoscopic cholecystectomy, requiring a same-day emergency living donor liver transplantation (LDLT). A 57-year-old man underwent elective laparoscopic cholecystectomy at an external facility. During the operation, uncontrolled bleeding from the liver hilum led to conversion to open surgery. Despite attempts to control the bleeding with sutures, the patient developed abnormal liver enzymes postoperatively. A computed tomography scan revealed necrosis of the right liver lobe and hypoplasia of the left lobe, leading to the patient to be transferred to our center. Upon admission, the patient was found to have encephalopathy, coagulopathy, hypotension, and oliguria, with elevated transaminase levels. Based on these findings, an emergency LT was deemed necessary. Due to the unavailability of a cadaveric organ, the patient's daughter was prepared as a living donor. Exploratory laparotomy revealed a necrotic right liver lobe, atrophic left lobe, transection of the right hepatic artery and common bile duct, and a thrombosed right portal vein. The patient successfully underwent LDLT from his daughter within 24 hours. At the seventh-month follow-up, he had no complications. Hepatic vascular injury during laparoscopic cholecystectomy can lead to ALF, which carries a high mortality risk. In such cases, LDLT may be a life-saving strategy. Early referral of a patient with ALF to a transplant center is life-saving.</p>","PeriodicalId":94258,"journal":{"name":"Transplantation proceedings","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143694977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Empagliflozin on Cardiac Arrhythmias and Heart Rate Variability in Kidney Transplant Recipients.","authors":"Kenan Evren Öztop, Yusuf Can, Mahmud İslam, Taner Demirci, Gözde Cakırsoy Çakar, Necattin Fırat, Musa Pınar, Zafer Ercan, Emrah Akın, Salih Salihi, Ahmed Cihad Genç, Fatih Altıntoprak, Hamad Dheir","doi":"10.1016/j.transproceed.2025.02.045","DOIUrl":"https://doi.org/10.1016/j.transproceed.2025.02.045","url":null,"abstract":"<p><strong>Aim: </strong>We aimed to investigate the effects of Empagliflozin on cardiac arrhythmias and heart rate variability in kidney transplant recipients (KTRs).</p><p><strong>Methods: </strong>Twenty-seven diabetic patients who underwent kidney transplantation between August 2020 and August 2023 were included. Patients with HbA1c >8% were received Empagliflozin treatment. A 24-hour Holter ECG monitoring was performed before and one year after beginning Empagliflozin. Holter ECGs were evaluated by a single cardiologist, comparing ventricular ectopic beats (VEB) and supraventricular ectopic beats (SEB) arrhythmias and heart rate variability parameters before and after one year of Empagliflozin treatment.</p><p><strong>Results: </strong>Twenty-seven patients completed the study, and the mean patient age was 56.1 ± 10 years. Fifteen of the patients (55.6%) were male. The mean duration since transplant before starting Empagliflozin was 62.8 ± 46.2 months. In follow-up, HbA1c decreased from 8.2% to 7.7%(P = .075), urine protein/creatinine ratio reduced from 0.437 ± 0.428 to 0.267 ± 0.146 gr/g (P = .056), and platelet count increased significantly (P = .004). After one year of treatment, the number of VEBs and SEBs in the patients decreased compared to pretreatment. They decreased from 173.5 ± 460.8 and 514.8 ± 265 beats before treatment to 125.1 ± 231.7 and 125.1 ± 231.7 beats after treatment, respectively, but did not reach statistical significance (P > .05). No significant changes were found in heart rate variability parameters (P > .05). No significant correlation was found between VEBs and SEBs and cardiac inflammation indicators (P > .05).</p><p><strong>Conclusion: </strong>This study, for the first time, investigated the effect of Empagliflozin on cardiac arrhythmias and heart rate variability in diabetic KTRs. Empagliflozin did not significantly affect cardiac arrhythmias and heart rate variability in KTRs.</p>","PeriodicalId":94258,"journal":{"name":"Transplantation proceedings","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143675123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}