Transplantation proceedings最新文献_第2页

Successful Oral Isavuconazole Monotherapy for Invasive Pulmonary Mucormycosis in Kidney Transplant Recipients: Case Reports and Literature Review.

Transplantation proceedings Pub Date : 2025-03-12 DOI: 10.1016/j.transproceed.2025.02.047

Zeng-Jie Wang, Jue Zhang, Yun-Ying Shi

引用次数: 0

Saliva Samples as a Potential Tool for the Diagnosis and Monitoring of Cytomegalovirus Reactivation in Children Undergoing Transplantation.

Transplantation proceedings Pub Date : 2025-03-10 DOI: 10.1016/j.transproceed.2025.02.023

Alejandra Pando-Caciano, Pauline E Mamaní-Cajachagua, Alejandra A Ingunza-Tapia, Gerardo J Sánchez-García, Xiomara L Caffo-Valentín, Emiliana Rizo-Patrón, Sergio A Murillo-Vizcarra, Holger Maita-Malpartida

{"title":"Saliva Samples as a Potential Tool for the Diagnosis and Monitoring of Cytomegalovirus Reactivation in Children Undergoing Transplantation.","authors":"Alejandra Pando-Caciano, Pauline E Mamaní-Cajachagua, Alejandra A Ingunza-Tapia, Gerardo J Sánchez-García, Xiomara L Caffo-Valentín, Emiliana Rizo-Patrón, Sergio A Murillo-Vizcarra, Holger Maita-Malpartida","doi":"10.1016/j.transproceed.2025.02.023","DOIUrl":"https://doi.org/10.1016/j.transproceed.2025.02.023","url":null,"abstract":"Background: Regular monitoring of cytomegalovirus (CMV) reactivation in children who undergo transplantation is performed by molecular testing on blood samples. This highlights the need to explore noninvasive alternatives, such as saliva. The present study evaluated the usefulness of saliva samples for detecting and monitoring CMV reactivation in children undergoing transplantation at a referral center in Lima, Peru.Methods: A total of 85 paired samples of liquid saliva and whole blood and 91 paired samples of swab-collected saliva and whole blood from 16 children who underwent transplantation were analyzed by quantitative polymerase chain reaction (qPCR).Results: The positivity rates for whole blood, liquid, and swab-collected saliva were 12.59%, 15.29%, and 12.09%, respectively. No significant differences were observed in viral load among the samples, and there was no remarkable correlation or agreement between saliva and whole blood. However, 19 samples from 4 patients were positive in their saliva but negative in their respective whole blood pairs. One patient who was positive in both the saliva samples and negative in blood developed gastrointestinal CMV disease.Conclusions: Saliva may serve as a promising diagnostic tool for detecting and monitoring CMV reactivation in pediatric transplant recipients. Further studies should explore the significance of the saliva viral load to guide pre-emptive therapy and predict disease development.","PeriodicalId":94258,"journal":{"name":"Transplantation proceedings","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143607644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Serologic Evaluation for Severe Acute Respiratory Syndrome Coronavirus 2 in Pediatric Heart Transplantation Recipients and Patients on a Pediatric Heart Transplantation Waiting List in a Quaternary Hospital. 对一家四级医院的小儿心脏移植受者和小儿心脏移植候诊患者进行严重急性呼吸综合征冠状病毒 2 血清学评估。

Transplantation proceedings Pub Date : 2024-06-01 Epub Date: 2024-05-17 DOI: 10.1016/j.transproceed.2024.04.023

Clarice Arruda Villari, Adailson Siqueira, Celia Strunz, Christiane Moscan, Marcelo Jatene, Nana Miura, Estela Azeka

{"title":"Serologic Evaluation for Severe Acute Respiratory Syndrome Coronavirus 2 in Pediatric Heart Transplantation Recipients and Patients on a Pediatric Heart Transplantation Waiting List in a Quaternary Hospital.","authors":"Clarice Arruda Villari, Adailson Siqueira, Celia Strunz, Christiane Moscan, Marcelo Jatene, Nana Miura, Estela Azeka","doi":"10.1016/j.transproceed.2024.04.023","DOIUrl":"10.1016/j.transproceed.2024.04.023","url":null,"abstract":"Background: The Coronavirus disease 2019 (COVID-19) pandemic has been a global reality for longer than 3 years. Serologic studies have great importance for understanding the virus's behavior in populations, as it can suggest the status of the epidemic in a community. This cross-sectional study aimed to analyze the serologic profile for COVID-19 in patients before and after pediatric heart transplantation.Methods: Serology data on IgG and IgM antibodies for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were collected in patients of the Pediatric Cardiology and Congenital Heart Diseases unit of a Brazilian hospital between January and August 2022. A total of 174 patients were recruited, including 28 on the transplantation waiting list and 146 heart transplant recipients. Information for each patient, including demographics (age, sex, state of origin), type of heart disease (congenital or acquired), and time after transplantation, was analyzed.Results: Overall, 72 patients had a positive serology for anti-N antibodies (48.0%), including 62 heart transplant recipients and 10 patients on the transplantation waiting list, The positivity rates in these 2 groups were 48.1% and 47.6%, respectively. Positivity rates for previously infected individuals were 62.5% and 62.1%, respectively.Conclusions: Approximately one-half of our study sample had IgM or IgG antibodies against the SARS-CoV-2 virus. Serologic studies on the duration and level of protection provided by these antibodies are relevant public health tools for health promotion of vulnerable groups and can be useful for future studies on antibody behavior.","PeriodicalId":94258,"journal":{"name":"Transplantation proceedings","volume":" ","pages":"1112-1114"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140961354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of COVID-19 Infection in Kidney Transplant Recipients. 肾移植受者的 COVID-19 感染分析

Transplantation proceedings Pub Date : 2024-06-01 Epub Date: 2024-05-17 DOI: 10.1016/j.transproceed.2024.04.016

Thamiris Quiqueto Marinelli, Heloisa Cristina Caldas, Maria Alice Sperto Ferreira-Baptista, Fernanda Salomão Gorayeb-Polacchini, Ana Carolina Brecher Souza, Ludimila Leite Marzochi, Guilherme Jairo Luiz da Silva, Ida Maria Maximina Fernandes-Charpiot, Mario Abbud-Filho

{"title":"Analysis of COVID-19 Infection in Kidney Transplant Recipients.","authors":"Thamiris Quiqueto Marinelli, Heloisa Cristina Caldas, Maria Alice Sperto Ferreira-Baptista, Fernanda Salomão Gorayeb-Polacchini, Ana Carolina Brecher Souza, Ludimila Leite Marzochi, Guilherme Jairo Luiz da Silva, Ida Maria Maximina Fernandes-Charpiot, Mario Abbud-Filho","doi":"10.1016/j.transproceed.2024.04.016","DOIUrl":"10.1016/j.transproceed.2024.04.016","url":null,"abstract":"Background: COVID-19, caused by SARS-CoV-2, was responsible for higher morbidity and mortality in renal transplant recipients (RTx). The objective of the study was to evaluate the impact of COVID-19 infection on RTx in a single center in Brazil.Methods: A cohort of 135 RTx was evaluated between December 2019 and June 202l, and demographics, clinical, and laboratory profiles were analyzed from deceased donors with COVID-19.Results: Diabetic and RTx from extended criterion donors presented more frequently the severe form of the disease. Serum creatinine (sCr) after 3 months of diagnosis of COVID-19 varied according to the severity of infection. The lethality rate was higher in the group with severe symptoms (65%) compared with those with mild infection (1.5%).Conclusion: The increase in sCr was associated with disease severity. The lethality rate for COVID-19 was 26.6%. These rates are 10-20 times higher than those reported in the general population and suggest that rigorous observation, early diagnosis, and disease prevention measures are crucial in RTx.","PeriodicalId":94258,"journal":{"name":"Transplantation proceedings","volume":" ","pages":"1048-1051"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140961316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pneumocystis jirovecii Pneumonia in a Liver Transplant Recipient With an Adverse Reaction to Trimethoprim/Sulfamethoxazole Treated With a Sulfonamide Desensitization Protocol: Case Report. 用磺胺脱敏方案治疗一名对三甲氧苄青霉素/磺胺甲噁唑有不良反应的肝移植受者的吉罗韦氏肺孢子菌肺炎：病例报告。

Transplantation proceedings Pub Date : 2024-05-01 DOI: 10.1016/j.transproceed.2024.03.022

Karolina Baran, A. Furmańczyk-Zawiska, R. Wieczorek-Godlewska, Przemysław Nitek, Magdalena Durlik

引用次数: 0

Current Data on Organ Donation and Transplantation in Poland: Poltransplant Activity 2017 to 2022. 波兰器官捐献和移植的当前数据：2017年至2022年波兰器官移植活动》。

Transplantation proceedings Pub Date : 2024-05-01 Epub Date: 2024-05-17 DOI: 10.1016/j.transproceed.2024.03.027

Jarosław Czerwiński, Anna Pszenny, Krystyna Antoszkiewicz, Teresa Danek, Łukasz Górski, Małgorzata Hermanowicz, Anna Łęczycka, Piotr Malanowski, Adam Parulski, Łukasz Szemis, Jacek Ziaja, Artur Kamiński

引用次数: 0

E. Solowiej, J. Solowiej, M. Godlewski, et al. Regarding the article "Application of Sulforaphane: histopathological study of intraportal transplanted pancreatic islets into livers of diabetic rats," Transplant Proc (2006 Jan/Feb) 38(1): pages 282-283. E.Solowiej, J. Solowiej, M. Godlewski, et al. 关于文章 "红景天的应用：对糖尿病大鼠肝脏内移植胰岛的组织病理学研究"，Transplant Proc (2006 Jan/Feb) 38(1): pages 282-283.

Transplantation proceedings Pub Date : 2009-06-01

引用次数: 0