The International journal of oral & maxillofacial implants最新文献

筛选
英文 中文
Thermal Changes During Digital Guided Implant Surgery Using the Conventional and Single Drill Protocols.
The International journal of oral & maxillofacial implants Pub Date : 2025-01-31 DOI: 10.11607/jomi.11066
Aritza Brizuela-Velasco, Daniel Robles, Saray Fernández-Hernández, José Manuel Mendes, Ignacio Sanz, Javier Gil
{"title":"Thermal Changes During Digital Guided Implant Surgery Using the Conventional and Single Drill Protocols.","authors":"Aritza Brizuela-Velasco, Daniel Robles, Saray Fernández-Hernández, José Manuel Mendes, Ignacio Sanz, Javier Gil","doi":"10.11607/jomi.11066","DOIUrl":"https://doi.org/10.11607/jomi.11066","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to compare heat generation during osteotomy for dental implant placement using conventional (sequential drilling) and single drill protocol in digitally guided surgery and to clarify differences in thermal exposure time.</p><p><strong>Materials and methods: </strong>In this study, we used a bovine rib ex vivo model with a surgical splint and a type K thermocouple to measure temperature and time. The conventional protocol (n=20) involved sequential drilling using 6 drills of increasing diameter, while the simplified protocol used a single drill (n=20). On the other hand, four implant beds were prepared in the tibia of a New Zealand rabbit to compare the mean temperature values between the in vivo and ex vivo models.</p><p><strong>Results: </strong>Student's t-test revealed no significant differences (p=0.1688) in temperature elevation between the conventional drilling (mean, 1.977°C; sd 1.165) and single drilling (mean, 2.634°C; sd 1.734) protocols. However, significant differences between the groups were found in the exposure time: 107.105 seconds (sd 29.196) and 16.842 (sd 8.101) respectively. The mean temperature increase due to drilling was 0.365°C (sd 0.204) and 0.378°C (sd 0.381) in the rabbit tibia and bovine rib, respectively, with no significant differences (p-value = 0.926) between the in vivo and ex vivo models.</p><p><strong>Conclusions: </strong>Conventional and single drill guided surgery protocols for implant bed preparation generate similar temperatures in vitro. Exposure time is longer with conventional protocols than with single drill protocols.</p>","PeriodicalId":94230,"journal":{"name":"The International journal of oral & maxillofacial implants","volume":"0 0","pages":"1-22"},"PeriodicalIF":0.0,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143071179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Primary Stability on Short vs. Conventional -Implants with Reverse Concave Neck.
The International journal of oral & maxillofacial implants Pub Date : 2025-01-31 DOI: 10.11607/jomi.11263
Daniel Greenberg, Nathan Estrin, Rafael Delgado-Ruiz, Georgios E Romanos
{"title":"Effect of Primary Stability on Short vs. Conventional -Implants with Reverse Concave Neck.","authors":"Daniel Greenberg, Nathan Estrin, Rafael Delgado-Ruiz, Georgios E Romanos","doi":"10.11607/jomi.11263","DOIUrl":"https://doi.org/10.11607/jomi.11263","url":null,"abstract":"<p><p>Vertical ridge augmentation has less long-term predictability than horizontal ridge augmentation due to common complications with vertical Guided Bone Regeneration (GBR), including early exposure of the barrier membrane and decreased bone stability.</p><p><strong>Objective: </strong>The purpose of this study was to evaluate the primary stability of short implants versus conventional implants, in vitro.</p><p><strong>Methods: </strong>Two groups of implants with reverse concave neck and neck micro threads (ULT, Ditron Dental, CA) were studied; short implants (Ø 6.0mm x 7mm) and conventional implant (Ø 3.75mm x 10mm). A total of 80 implants were placed by the same calibrated clinician at 800RPM, 40 short implants and 40 conventional implants. Each implant was placed in dense (type II) and soft (type IV) bone. Implant primary stability was recorded using insertion torque (IT), Resonance Frequency Analysis (RFA), and Periotest values. Statistical comparison with Analysis of Variance were completed to compare differences between groups.</p><p><strong>Results: </strong>The comparison of IT, RFA and Periotest of the two groups of implants showed statistical significance (P<0.0001) favoring the short implants (Ø 6.0mm x 7mm) in both the soft and dense bone qualities.</p><p><strong>Conclusion: </strong>Within the limitations of this study, short implants with wide diameter seem to have a higher level of implant stability compared to narrow implants with conventional length.</p>","PeriodicalId":94230,"journal":{"name":"The International journal of oral & maxillofacial implants","volume":"0 0","pages":"1-13"},"PeriodicalIF":0.0,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143071331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Horizontal Guided Bone Regeneration: L-PRF Bone-Block Vs A Mixture of Autogenous Bone with Deproteinized Bovine Bone Mineral. A Split-Mouth RCT Study with 25 Months Follow-Up.
The International journal of oral & maxillofacial implants Pub Date : 2025-01-31 DOI: 10.11607/jomi.11095
Rutger A L Dhondt, Marc Quirynen, Pierre Lahoud, Simone Cortellini, Andy Temmerman
{"title":"Horizontal Guided Bone Regeneration: L-PRF Bone-Block Vs A Mixture of Autogenous Bone with Deproteinized Bovine Bone Mineral. A Split-Mouth RCT Study with 25 Months Follow-Up.","authors":"Rutger A L Dhondt, Marc Quirynen, Pierre Lahoud, Simone Cortellini, Andy Temmerman","doi":"10.11607/jomi.11095","DOIUrl":"https://doi.org/10.11607/jomi.11095","url":null,"abstract":"<p><strong>Purpose: </strong>This study aims to assess the differences between a leukocyte- and platelet-rich fibrin (L-PRF) and deproteinized bovine bone mineral block and a combination of 50% autogenous bone (AB) and 50% deproteinized bovine bone mineral (DBBM) as grafting material for horizontal guided bone regeneration (GBR).</p><p><strong>Materials and methods: </strong>This randomized double-blind split-mouth clinical trial included 13 subjects requiring bilateral horizontal bone augmentation. Each patient received both treatment modalities: one side of the jaw was treated by GBR with the L-PRF and deproteinized bovine bone mineral block, and the other side with a 50/50 mixture of AB and DBBM. Cone beam computed tomography (CBCT) scans were used to evaluate horizontal bone width (HBW) and buccal bone thickness (BBT) at various time points: baseline (T0), immediately post-augmentation (T1), at implant placement (T2), and one year after abutment connection (T4). Bone sounding (BS) was also used to verify CBCT measurements.</p><p><strong>Results: </strong>No statistically significant differences were found in HBW gain between test (L-PRF) and control (AB/DBBM) sites at any timepoint. Both sites showed significant HBW loss post-implant placement, with more bone volume lost at higher crestal levels (Sh0 > Sh2 > Sh4). At the Sh2 level, 48.8% of the HBW gain at T1 was lost by T4 in test sites, and 46.2% in control sites. Similarly, BBT at Sh2 reduced from 4.7 ± 1.0 mm to 1.3 ± 1.5 mm in test sites and from 2.1 ± 1.0 mm to 0.9 ± 0.8 mm in control sites. Both groups of sites had one complication, resulting in a 91.6% success rate for both treatments. The cumulative survival rate of implants was 100% at 16 months, with a mean interproximal bone level (IBL) loss of 0.2 ± 0.9 mm and 0.1 ± 0.6 mm for test and control sites, respectively.</p><p><strong>Conclusions: </strong>No statistically significant differences were found between the AB/DBBM composite graft and the L-PRF and bovine bone mineral block for horizontal GBR. Significant resorption of grafted volume occurs within 25 months, continuing post-implant placement. Further research with larger sample sizes is needed to confirm these findings and optimize GBR techniques.</p>","PeriodicalId":94230,"journal":{"name":"The International journal of oral & maxillofacial implants","volume":"0 0","pages":"1-30"},"PeriodicalIF":0.0,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143070805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Qualitative Analysis of Implant-Bone Interface After Implant Placement Implementing Condensation Technique In Vitro.
The International journal of oral & maxillofacial implants Pub Date : 2025-01-31 DOI: 10.11607/jomi.11080
Yuriy Garaev, Nina K Anderson, Rafael Delgado-Ruiz, Georgios E Romanos
{"title":"Qualitative Analysis of Implant-Bone Interface After Implant Placement Implementing Condensation Technique In Vitro.","authors":"Yuriy Garaev, Nina K Anderson, Rafael Delgado-Ruiz, Georgios E Romanos","doi":"10.11607/jomi.11080","DOIUrl":"https://doi.org/10.11607/jomi.11080","url":null,"abstract":"<p><p>The release of titanium nanoparticles during implant placement in dense bone is a significant concern, as it can potentially have adverse effects on the peri-implant tissues and an impact on the etiology of peri-implant diseases. The objective of this study was to examine the presence of titanium nanoparticles at the bone-implant interface during implant placement utilizing the bone condensation technique in vitro. Artificial Type IV bone slices (4mm thick) were securely held in place with a vice. Two groups of implants were placed. One group (test group) was placed under the condensation technique using cylindrical osteotomes. The other group (control group) was placed following the traditional surgical protocol. Implants were placed in parallel between bone slices held in a vice. Three groups of implant designs (6 implants in each group) were inserted into the bone. Two implant designs consisted of implants made of pure titanium (grade 4), while the third implant design group was constructed of titanium alloy (Ti6Al4V). Subsequently, the blocks were separated, and the peri-implant bone interface was qualitatively evaluated for titanium presence using X-ray-fluorescence spectrometry (XFS) at the coronal, middle, and apical thirds of osteotomies (n=12/ implant system). Descriptive statistical analysis showing the mean values (&#43;/-SD) of titanium nanoparticles was performed. No detectable titanium levels were identified in the control group of titanium alloy-implants compared to pure titanium-implants. In contrast, the test group of all implant systems showed presence of titanium nanoparticles in coronal, middle, and apical thirds. Our results indicate that bone condensation technique is associated with titanium release during implant placement in vitro. These findings were shown for both pure titanium- and titanium alloy-dental implants.</p>","PeriodicalId":94230,"journal":{"name":"The International journal of oral & maxillofacial implants","volume":"0 0","pages":"1-14"},"PeriodicalIF":0.0,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143071171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influence of Dental Implant Diameters on Prosthesis Complications: a Systematic Review and Meta-analysis. 牙科植入物直径对修复体并发症的影响:系统回顾与元分析》。
The International journal of oral & maxillofacial implants Pub Date : 2025-01-31 DOI: 10.11607/jomi.10964
Yu-Ting Yeh, Lan-Lin Chiou, Hsuan-Hung Chen, Guo- Hao Lin, Richard T Kao, Donald A Curtis
{"title":"Influence of Dental Implant Diameters on Prosthesis Complications: a Systematic Review and Meta-analysis.","authors":"Yu-Ting Yeh, Lan-Lin Chiou, Hsuan-Hung Chen, Guo- Hao Lin, Richard T Kao, Donald A Curtis","doi":"10.11607/jomi.10964","DOIUrl":"https://doi.org/10.11607/jomi.10964","url":null,"abstract":"<p><strong>Purpose: </strong>This systematic review and meta-analysis aims to analyze the risk of prosthesis complications across different implant diameters.</p><p><strong>Materials and methods: </strong>An electronic search across PubMed (MEDLINE), Embase, Scopus, and Cochrane Central Register of Controlled Trials until December 2023 was performed. Studies comparing implant prosthesis complications among extra-narrow (<3.0 mm), narrow (≥3.0 to <3.75 mm), standard (≥3.75 to <5 mm), and wide-diameter (≥5 mm) implants were included. Meta-analyses were performed to evaluate the risk ratio of prosthesis complications across different diameters, particularly in non-full arch implant-supported fixed dental prostheses (ISFDP).</p><p><strong>Results: </strong>Eighteen clinical studies were included. In non-full arch ISFDP, the most prevalent complication was screw loosening in narrow, standard, and wide-diameter implants (17.28%, 4.08% and 12.45%, respectively), and decementation (3.4%) in extra-narrow diameter implants. In implant overdentures, extra-narrow, narrow and standard-diameter implants demonstrated high rates of retentive cap wear (58.33%, 80.49% and 70%, respectively), whereas wide-diameter implants had 16.67% overdenture repair. The meta-analyses showed a risk ratio of 0.20 (95% confidence interval= 0.04 to 0.94, p= 0.04) and 0.17 (95% CI= 0.06 to 0.45, p< 0.0004) for abutment fracture in single crowns and ISFDP comparing narrow versus standard-diameter implants. No significant differences in risk ratios were observed for screw loosening, decementation, porcelain chipping, fracture, or screw fracture among the different diameter groups.</p><p><strong>Conclusions: </strong>This systematic review highlights that screw loosening and retentive cap wear are the most common prosthesis complications in ISFDP and overdentures, regardless of implant diameter. While narrow-diameter implants have a lower risk of abutment fracture compared to standard-diameter implants, clinicians should carefully consider patient characteristics, implant locations, and abutment features when selecting the ideal implant diameter.</p>","PeriodicalId":94230,"journal":{"name":"The International journal of oral & maxillofacial implants","volume":"0 0","pages":"1-37"},"PeriodicalIF":0.0,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143071167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical and Radiographic Outcomes of Single-Unit Implant- Supported Restorations: A 12-Month Cross-Sectional Clinical Study. 单单元种植体支撑修复体的临床和影像学结果:一项为期12个月的横断面临床研究。
The International journal of oral & maxillofacial implants Pub Date : 2025-01-17 DOI: 10.11607/jomi.11233
Nur Pektaş, Özer İşisağ
{"title":"Clinical and Radiographic Outcomes of Single-Unit Implant- Supported Restorations: A 12-Month Cross-Sectional Clinical Study.","authors":"Nur Pektaş, Özer İşisağ","doi":"10.11607/jomi.11233","DOIUrl":"https://doi.org/10.11607/jomi.11233","url":null,"abstract":"<p><strong>Purpose: </strong>This retrospective clinical study aims to analyze single-unit implant-supported restorations' clinical and radiographic outcomes comprehensively.</p><p><strong>Materials and methods: </strong>In this retrospective study, patients who had undergone 12 months of implant-supported singleunit fixed prosthetic treatment were scanned from the archives, and a hundred patients were included in the study. Implant success and survival rates were assessed according to the consensus decisions published at the International Oral Implantology Congress in 2007. Prosthetic complications such as chipping, screw loosening, and decementation were also evaluated. In addition, success/survival rates and prosthetic compositions were associated with some surgical and prosthetic parameters.</p><p><strong>Results: </strong>According to the success/survival criteria, 88% of the implants were successful, 10% had satisfactory survival, and 2% had compromised survival. The risk of satisfactory or compromised survival was 62.5 times higher in individuals with inadequately keratinized mucosa compared to those with adequately keratinized mucosa (p < 0.001). It was also 5.736 times greater for extractions due to periodontal disease versus endodontic reasons (p = 0.010) and 4.629 times higher for implants with diameters less than 3.75 mm compared to those between 3.75 mm and 5 mm (p = 0.037). Screw loosening was observed in 15% of the evaluated restorations, decementation in 13% and chipping in 4%, and the risk of screw loosening was 4.444 times higher for screw retention abutments compared to standard abutments (p=0.015).</p><p><strong>Conclusion: </strong>Insufficient keratinized mucosa, periodontal problems leading to tooth extractions, and the use of narrowdiameter implants can negatively affect the success of implant procedures. Loosening in screw-retained restorations is due solely to screw loosening, which is a high risk for screwretained restorations. Loosening in cement-retained restorations, on the other hand, is caused by the decementation of the prosthetic restoration or loosening of the abutment screw supporting the restoration.</p>","PeriodicalId":94230,"journal":{"name":"The International journal of oral & maxillofacial implants","volume":"0 0","pages":"1-30"},"PeriodicalIF":0.0,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143019195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multivariate Analysis of the Influence of Primary and Secondary Stability in Relation to Dental Implant Characteristics: A Clinical Study of 445 Implants. 445颗种植体的临床研究:初级和次级稳定性对种植体特性影响的多变量分析。
The International journal of oral & maxillofacial implants Pub Date : 2025-01-17 DOI: 10.11607/jomi.11254
Fabián Pérez-González, Santiago Bazal-Bonelli, Luis Sánchez-Labrador, Luis Miguel Sáez-Alcaide, Héctor González-Menéndez, Carlos Obo-Vázquez, Jorge Cortés-Bretón Brinkmann
{"title":"Multivariate Analysis of the Influence of Primary and Secondary Stability in Relation to Dental Implant Characteristics: A Clinical Study of 445 Implants.","authors":"Fabián Pérez-González, Santiago Bazal-Bonelli, Luis Sánchez-Labrador, Luis Miguel Sáez-Alcaide, Héctor González-Menéndez, Carlos Obo-Vázquez, Jorge Cortés-Bretón Brinkmann","doi":"10.11607/jomi.11254","DOIUrl":"https://doi.org/10.11607/jomi.11254","url":null,"abstract":"<p><strong>Purpose: </strong>Implant stability (IS) is crucial to the success of any implant-based therapy. The present work aimed to determine the relationship between primary and secondary stability and a range of variables.</p><p><strong>Material and methods: </strong>This retrospective cohort study included a total of 169 patients, who received 445 dental implants. A case history for each participant was created. Data collection included each patient's age, implant design, length and diameter, bone type, and surgical factors. Implant Stability Quotient (ISQ) values were measured at baseline (T0: primary stability) and T1 (secondary stability). To calculate the ISQ values at T0, T1 and their differences in the variables age, design, length and diameter, a multivariate ANOVA test was performed to determine which variables acted as confounding factors and to adjust the ISQ values to these variables.</p><p><strong>Results: </strong>The main variables age, design, length and diameter were adjusted to their confounding factors. Regarding primary (T0) and secondary (T1) stability, statistically significant differences (p<0.05) were only found in implant diameter, with the larger the diameter, the greater the stability. In all the other main variables, no statistically significant differences were found for primary and secondary stability.</p><p><strong>Conclusions: </strong>It may be concluded, within the limitations of the study, that the implant diameter variable is the one that significantly affects the primary and secondary stability of the implant.</p>","PeriodicalId":94230,"journal":{"name":"The International journal of oral & maxillofacial implants","volume":"0 0","pages":"1-20"},"PeriodicalIF":0.0,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143019213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcomes of Surgical Treatment of Peri-Implantitis: A Retrospective Cohort Study. 种植体周围炎手术治疗的结果:一项回顾性队列研究。
The International journal of oral & maxillofacial implants Pub Date : 2025-01-17 DOI: 10.11607/jomi.11018
Claudia Ros-Alcaraz, Maria Camila Erazo-Puentes, Octavi Camps-Font, Marta García-García, Rui Figueiredo, Eduard Valmaseda-Castellón
{"title":"Outcomes of Surgical Treatment of Peri-Implantitis: A Retrospective Cohort Study.","authors":"Claudia Ros-Alcaraz, Maria Camila Erazo-Puentes, Octavi Camps-Font, Marta García-García, Rui Figueiredo, Eduard Valmaseda-Castellón","doi":"10.11607/jomi.11018","DOIUrl":"https://doi.org/10.11607/jomi.11018","url":null,"abstract":"<p><strong>Purpose: </strong>The available scientific evidence on the effectiveness of the surgical treatment of peri-implantitis is limited. The aim of this study was to assess the risk of recurrence or disease progression in patients with peri-implantitis that underwent surgical treatment.</p><p><strong>Materials and methods: </strong>A retrospective cohort study was carried out in patients subjected to peri-implant surgery between 2015 and 2021, and with a minimum follow-up of 12 months. Data were analyzed using simple binary logistic regression models at patient level and generalized estimation equations at implant level.</p><p><strong>Results: </strong>A total of 34 patients and 103 implants were analyzed (70 undergoing resective techniques and 33 regenerative procedures). Fifteen patients (44.12%) experienced peri-implantitis recurrence and one patient (2.9%) lost one implant. No differences were found between the surgical techniques (p = 0.56). A history of periodontitis (ORa = 4.62; 95%CI: 1.14 to 18.75; p = 0.032), maxillary location (ORa = 9.69; 95%CI: 1.81 to 51.87; p = 0.008) and two implants treated per procedure (ORa = 31.68; 95%CI: 3.91 to 256.54; p = 0.001) were seen to increase the risk of recurrence.</p><p><strong>Conclusions: </strong>Almost half of all patients (44%) undergoing surgical treatment of periimplantitis will present disease progression or recurrence. This risk seems to be higher in patients with several treated implants, with a history of periodontal disease, or when the maxilla is involved.</p>","PeriodicalId":94230,"journal":{"name":"The International journal of oral & maxillofacial implants","volume":"0 0","pages":"1-22"},"PeriodicalIF":0.0,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143019219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Paired-Related Homeobox 1-Positive Cells Are Needed for Osseointegration. 骨结合需要成对相关同源框 1 阳性细胞
The International journal of oral & maxillofacial implants Pub Date : 2024-12-11 DOI: 10.11607/jomi.10852
Xi Feng, Haicheng Wang, Yuteng Weng, Yongliang Chen, Jie Huang, Zuolin Wang
{"title":"Paired-Related Homeobox 1-Positive Cells Are Needed for Osseointegration.","authors":"Xi Feng, Haicheng Wang, Yuteng Weng, Yongliang Chen, Jie Huang, Zuolin Wang","doi":"10.11607/jomi.10852","DOIUrl":"10.11607/jomi.10852","url":null,"abstract":"<p><strong>Purpose: </strong>To explore the contribution of paired-related homeobox 1-positive (Prrx1&#43;) cells to the implant-induced osseointegration process in adult alveolar bone and the potential underlying mechanisms.</p><p><strong>Materials and methods: </strong>Crerecombinase-induced lineage tracing and cell ablation were conducted in a murine dental implant model. Scratch and transwell assays were used to assess MC3T3-E1 cell migration after paired-related homeobox 1 overexpression. Single-cell RNA sequencing was applied to identify potential genes involved in Prrx1&#43; cell-driven osteogenesis.</p><p><strong>Results: </strong>Prrx1&#43; cells were observed to accumulate in the peri-implant area in a time-dependent manner; the number of these cells was found to reach its maximum on day 14. Osseointegration in mice was noticeably impaired after ablation of Prrx1&#43; cells. Further, it was discovered that Prrx1 promotes MC3T3-E1 cell migration, a process which is indispensable for sound healing of peri-implant tissue. Finally, semaphorin 3C (Sema3C) was detected exclusively and abundantly expressed by Prrx1&#43; cells. Knockdown of Sema3C in Prrx1&#43; cells significantly weakened their osteogenic potential.</p><p><strong>Conclusions: </strong>Our data suggest that Prrx1&#43; cells contribute to the osseointegration process under stress stimulation and Sema3C may play a critical role in Prrx1&#43; cell-driven osteogenesis. Prrx1 could significantly promote MC3T3-E1 cell migration.</p>","PeriodicalId":94230,"journal":{"name":"The International journal of oral & maxillofacial implants","volume":"0 0","pages":"893-903"},"PeriodicalIF":0.0,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140159811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Extracorporeal Shockwave Therapy (ESWT)-A Novel Method for Transferring Oral Implant Primary Failures to Final Clinical Success: A Test Case Report Followed up for More Than 6 Years. 体外冲击波疗法 (ESWT),一种将口腔种植失败转为最终临床成功的新方法:超过 6 年的试验病例跟踪报告。
The International journal of oral & maxillofacial implants Pub Date : 2024-12-11 DOI: 10.11607/jomi.10820
Luis Amengual, Manuel Brañes, Francisco Marchesani, Leopodo Parada, Maria Constanza Jara, Tomas Albrektsson
{"title":"Extracorporeal Shockwave Therapy (ESWT)-A Novel Method for Transferring Oral Implant Primary Failures to Final Clinical Success: A Test Case Report Followed up for More Than 6 Years.","authors":"Luis Amengual, Manuel Brañes, Francisco Marchesani, Leopodo Parada, Maria Constanza Jara, Tomas Albrektsson","doi":"10.11607/jomi.10820","DOIUrl":"10.11607/jomi.10820","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the feasibility of reversing a primary failure through therapeutic mechanical stimulation induced by transcutaneous application of acoustic waves (extracorporeal shockwave therapy [ESWT]) in the peri-implant tissues.</p><p><strong>Materials and methods: </strong>This clinical report evaluates the outcome of a new protocol proposed to treat a primary failure (loosened oral implant): application of three cycles of ESWT (one session per week for 3 consecutive weeks) with an equivalent positive energy of 0.18 mJ/mm2 (therapeutic dose: 2,000 pulses, 8 Hz, 4.0 bar). Standardized intraoral radiographs and CBCT scans were taken, the implant stability quotient (ISQ) was determined, and clinical evaluations were performed.</p><p><strong>Results: </strong>It was possible to verify a progressive increase in ISQ values after the ESWT protocol: 17 initially, 46 at 2 months, and 68 at 4 months. This led to successful implant prosthetic rehabilitation (35 Ncm). Follow-up evaluations at 6 years confirm that the new bone-implant interface is preserved and that ESWT is a safe, noninvasive treatment.</p><p><strong>Conclusions: </strong>In the context of the new dynamic model of osseointegration (the foreign body equilibrium), this represents the first report of a host-implant equilibrium reestablished after an early implant failure process. However, more studies are needed to determine both the medical device and the most effective therapeutic range for clinical applications of this technology in oral implantology.</p>","PeriodicalId":94230,"journal":{"name":"The International journal of oral & maxillofacial implants","volume":"0 0","pages":"922-930"},"PeriodicalIF":0.0,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140159868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信