The International journal of oral & maxillofacial implants最新文献

{"title":"Implants as Surveyed Crowns for Implant-Assisted Removable Partial Dentures: A Long-Term Case Series Study.","authors":"Shing-Zeng Dung, Shyh-Yuan Lee, Jea-Shen Tsai, I-Shiang Tzeng","doi":"10.11607/jomi.11202","DOIUrl":"https://doi.org/10.11607/jomi.11202","url":null,"abstract":"<p><strong>Purpose: </strong>Long-term data on the use of implants as surveyed crowns for implant-assisted removable partial dentures (IARPDSCs) are limited. This study evaluated the long-term outcomes and assessed the risk factors associated with marginal bone loss (MBL) in IARPDSCs.</p><p><strong>Materials and methods: </strong>A total of 51 implants were placed in 14 partially or fully edentulous patients and restored using IARPDSCs. Implant crowns or bridges served as abutments for the removable partial dentures (RPDs) to enhance their esthetics, comfort, and function. All patients attended regular follow-up appointments every 3-6 months for up to 12.5 years; these visits included professional cleaning and oral hygiene reinforcement. The collected data included patient demographics, treatment modality, arch restoration, Kennedy classification, RPD connection and retention design, opposing dentition, implant characteristics (location, connection type, and diameter), and any complications. The clinical assessments included plaque score, bleeding on probing, probing depth, marginal tissue recession, and keratinized mucosa width. Univariate and multivariate analyses were performed to identify factors influencing the MBL of implants in IARPDSCs.</p><p><strong>Results: </strong>One implant failed during follow-up; thus, the implant survival rate was 98%. All patients were satisfied with their prostheses and reported only minor complications. Univariate analysis showed a significantly higher MBL in maxillary implants than in mandibular implants (P = .045). Multiple regression analysis revealed that bruxism (P = .002) and maxillary implants (P = .013) were significantly associated with a higher MBL. Female sex (P = .051) and anterior implants (P = .058) exhibited a trend toward an association with higher MBL.</p><p><strong>Conclusions: </strong>Within the limitations of this retrospective clinical study, IARPDSCs demonstrated predictable long-term success in carefully selected and well-maintained patients.</p>","PeriodicalId":94230,"journal":{"name":"The International journal of oral & maxillofacial implants","volume":"0 0","pages":"1-27"},"PeriodicalIF":0.0,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142607869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Occlusal and Axial Thickness on the Fracture Load of Implant-Supported Monolithic Zirconia Crowns.","authors":"Min-Gyung Seo, Kyung-Ho Ko, Yoon-Hyuk Huh, Chan-Jin Park, Lee-Ra Cho","doi":"10.11607/jomi.11086","DOIUrl":"https://doi.org/10.11607/jomi.11086","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the fracture load of monolithic zirconia crowns with implant screw holes, focusing on variations in occlusal and axial thicknesses, and to assess the interaction between these variables.</p><p><strong>Materials and methods: </strong>Six different prostheses were designed using CAD software, varying in occlusal thickness (0.5 mm, 1.0 mm) and axial thickness (0.4 mm, 0.8 mm, 1.2 mm) based on the height and thickness differences of the titanium implant abutment. Twelve specimens per design were created by milling zirconia blocks and titanium abutments. These specimens were cemented with resin and subjected to thermomechanical aging (50 N, 200,000 cycles, 5°C-55°C, 30 seconds dwell time) using a chewing simulator. Static loading was applied using a universal testing machine at a rate of 0.5 mm/min until fracture occurred, and the load value (N) at the moment of the initial fracture was recorded. Fracture pattern and surface analyses were performed. Statistical analyses included two-way analysis of variance, Tukey HSD test, multiple regression analysis, and Fisher's exact test.</p><p><strong>Results: </strong>Both occlusal and axial thicknesses significantly influenced the fracture load (P < .05), with a significant interaction between them (P < .05). An occlusal thickness of 1.0 mm exhibited a significantly higher fracture load compared to 0.5 mm (P < .05). An axial thickness of 1.2 mm showed a significantly higher fracture load compared to 0.4 mm and 0.8 mm (P < .05). The difference in axial thickness between 0.8 mm and 1.2 mm had a more substantial impact on fracture load than the difference in occlusal thickness between 0.5 mm and 1.0 mm (P < .05). Fractographic analysis showed that the thin axial wall exhibited twist hackles without involvement of the crown margin, whereas the thick axial wall exhibited no hackles and a more catastrophic failure involving the crown margin.</p><p><strong>Conclusion: </strong>For monolithic zirconia crowns with implant screw holes, when sufficient occlusal thickness cannot be achieved, an axial thickness of at least 1.2 mm is recommended to ensure higher fracture resistance.</p>","PeriodicalId":94230,"journal":{"name":"The International journal of oral & maxillofacial implants","volume":"0 0","pages":"1-22"},"PeriodicalIF":0.0,"publicationDate":"2024-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142515586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Innovative 3D-Printed Titanium Specimens Favor a Modulation of Inflammation in Dental Pulp Stem Cells During Liposome-Triggered Mineralization.","authors":"Marialucia Gallorini, Alessia Ricci, Serena Pilato, Antonella Fontana, Carlo Mangano, Amelia Cataldi, Susi Zara","doi":"10.11607/jomi.11129","DOIUrl":"https://doi.org/10.11607/jomi.11129","url":null,"abstract":"<p><strong>Purpose: </strong>developing customized titanium specimens, with innovative surfaces, is a suitable strategy to overcome implant failure. Additionally, a faster and efficient osteogenic commitment assists tissue regeneration. To investigate the interplay between inflammation and differentiation upon implantation, Dental Pulp Stem Cells (DPSCs) were cultured on 3D-printed titanium owning an internal open cell form, administering osteogenic factors by a liposomal formulation (LipoMix) compared to traditional delivery of differentiation medium (DM).</p><p><strong>Materials and methods: </strong>osteogenic differentiation was evaluated by western blot, by measuring β1 integrin expression, and by and real-time RT-PCR, by measuring SP7 and Collagen I gene expression; while.angiogenesis was characterized by measuring VEGF secretion levels. Matrix mineralization was assessed by means of Alizarin Red Staining, cell adhesion and inflammation responses through western blot, enzymatic and ELISA assays evaluating Nrf2 expression, catalase activity and Prostaglandin E2 secretion, respectively.</p><p><strong>Results: </strong>LipoMix enhances cell proliferation and adhesion, as revealed by increased integrin β1 expression. Mineralized matrix deposition, SP7 gene expression, Collagen I release and Alkaline Phosphatase activity appear increased in LipoMix condition. Additionally, the redox-sensitive transcription factor Nrf2 is overexpressed at the earliest experimental times, triggering the catalase activity.</p><p><strong>Conclusions: </strong>data reported confirm that internal topography and post-production treatments on titanium surfaces dynamically and positively condition the DPSC progress towards the osteogenic phenotype, moreover, the combination with LipoMix fastens the positive modulation of inflammation under osteogenic conditions. Therefore, the development of customized surfaces along with the administration of differentiating factors enclosed in a liposomal delivery system, could represent a promising and innovative tool in regenerative dentistry.</p>","PeriodicalId":94230,"journal":{"name":"The International journal of oral & maxillofacial implants","volume":"0 0","pages":"1-31"},"PeriodicalIF":0.0,"publicationDate":"2024-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142515587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Zirconia Thickness, Cement Color, and Titanium Implant Abutment Surface Treatment Type on the Esthetic Outcomes of High-Translucency Monolithic Zirconia.","authors":"Chayanan Sirawuttipong, Mali Palanuwech","doi":"10.11607/jomi.10672","DOIUrl":"10.11607/jomi.10672","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the esthetic outcomes based on the color differences in zirconia (Zr) of varying thickness, resin cement color, and types of titanium (Ti) implant surface treatments.</p><p><strong>Materials and methods: </strong>Overall, 28 high-translucency monolithic zirconia (HTMZ) specimens were arranged into four groups based on Zr thickness: 1.0, 1.5, 2.0, and 2.5 mm (n &#61; 7 per thickness). Each group was tested using two resin cement colors (clear and opaque) in combination with six surface-treated Ti groups (n &#61; 7), including untreated titanium (UT), anodization (AN), 50-μm alumina airborne-particle abrasion followed by AN (SBAN), AN followed by 50-μm alumina airborne-particle abrasion (ANSB), 9.5% hydrofluoric acid followed by AN (HFAN), and AN followed by 9.5% hydrofluoric acid (ANHF). This created a total of 48 experimental groups, including the use of composite resin (n &#61; 7, shade A2D) for four control groups. All specimens were measured using a spectrophotometer and subsequently compared with composite resin (control) with the corresponding Zr thickness to establish color differences. A color difference of < 2.7 was considered clinically acceptable. The data obtained were statistically analyzed using ANOVA and post hoc test (P &#61; .05).</p><p><strong>Results: </strong>Zr thickness, resin cement color, and type of Ti implant surface treatment significantly affected the observed color differences (P < .05). When using 2.5-mm HTMZ with clear resin cement on AN, UT, SBAN, HFAN, and ANSB, the mean color differences were below the clinically acceptable values, and the 95% CIs of color differences were below the clinically acceptable values for AN, UT, and SBAN groups.</p><p><strong>Conclusions: </strong>HTMZ with a minimum thickness of 2.5 mm and clear resin cement on AN, UT, and SBAN groups potentially result in acceptable color matching with 95% CIs.</p>","PeriodicalId":94230,"journal":{"name":"The International journal of oral & maxillofacial implants","volume":"0 0","pages":"765-775"},"PeriodicalIF":0.0,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139731356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alveolar Buccal Bone Overbuilding Before Tooth Extraction: A Preclinical Study.","authors":"Takahisa Iida, Michihide Miki, Mauro Ferri, Fernando M Muñoz Guzon, Gianfranco Cesaretti, Daniele Botticelli","doi":"10.11607/jomi.10754","DOIUrl":"10.11607/jomi.10754","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the dimensional changes in the alveolar crest after buccal overbuilding was performed prior to tooth extraction in a dog model.</p><p><strong>Materials and methods: </strong>At the test sites, alveolar crest overbuilding was performed on the buccal aspect of the distal root of the third premolar using xenograft covered with a collagen membrane. No treatment was applied at the control sites. After 3 months, the distal roots of both third premolars were extracted and implants were immediately placed into the alveolus, allowing nonsubmerged healing. After 3 months, biopsy samples were collected.</p><p><strong>Results: </strong>Upon histologic analysis, no statistically significant differences in hard tissue dimensions were found. The buccal bone plate at the test sites presented a tendency for higher resorption compared to the control sites. However, if the contribution of the residue of biomaterial is considered, a higher volumetric gain was registered at the test than at the control sites.</p><p><strong>Conclusions: </strong>The buccal overbuilding performed prior to tooth extraction did not contribute to the preservation of the alveolar crest dimensions after extraction. This could be due to failure to incorporate the graft into the newly formed bone.</p>","PeriodicalId":94230,"journal":{"name":"The International journal of oral & maxillofacial implants","volume":"0 0","pages":"713-722"},"PeriodicalIF":0.0,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140066412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analyzing Linear and Angular Deviations After Guided Surgery for Dental Implant Placement: A Preliminary Study.","authors":"Catarina Mendes Fonseca, Patrícia Alexandra Barroso da Fonseca, Margarida Martins Quezada, Tiago Marques, Javier Montero, Dean Morton, André Correia","doi":"10.11607/jomi.10787","DOIUrl":"10.11607/jomi.10787","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the accuracy and precision of prosthetically driven implant placement achieved through static computer-aided implant surgery by analyzing the linear and angular deviations of implants.</p><p><strong>Materials and methods: </strong>A total of 53 implants were included in the study. The implants were positioned using either tooth-supported templates or tooth-and-tissue-supported templates with fixation pins. Two distinct guided surgery approaches were used: pilot drill guided and fully guided. 3D data from the implant planning phase was superimposed with the 3D data from the final implant positions using the 'Treatment Evaluation' tool within coDiagnostiX implant planning software (Straumann). This enabled the automatic calculation of deviations in implant placement accuracy.</p><p><strong>Results: </strong>The average angular deviation observed was 3.90 degrees. For linear deviations, the mean 3D deviation was 1.04 mm at the most coronal point of the implants and 1.56 mm at the implant apex.</p><p><strong>Conclusions: </strong>This research demonstrates the feasibility of a digital workflow for guided implant surgery, offering a promising treatment option. Nonetheless, it is important to note that deviations do occur, particularly in the apical region of the implant. Care should be taken, particularly in cases of limited bone availability.</p>","PeriodicalId":94230,"journal":{"name":"The International journal of oral & maxillofacial implants","volume":"0 0","pages":"738-744"},"PeriodicalIF":0.0,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139941411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Antidepressants on Dental Implant Failure: A Systematic Review and Meta-analysis.","authors":"Liza Harutyunyan, Kayla Lieuw, Bryan Yang, Eric Lee, Yu-Ting Yeh, Hsuan-Hung Chen, Guo-Hao Lin","doi":"10.11607/jomi.10798","DOIUrl":"10.11607/jomi.10798","url":null,"abstract":"<p><strong>Purpose: </strong>To analyze the risk of dental implant failure for patients with a history of antidepressant use through a systematic review and meta-analysis.</p><p><strong>Materials and methods: </strong>An electronic search was performed up to June 2023 in three databases including PubMed/MEDLINE, Web of Science, and Cochrane Central Register of Controlled Trials; data on the comparison of implant failure rate for patients with and without the use of antidepressants were included. Meta-analyses for the risk ratio of implant failure rate at patient level and implant level were performed.</p><p><strong>Results: </strong>Overall, 11 clinical studies were selected for inclusion in this review. The meta-analyses showed a risk ratio of 2.44 (95% CI &#61; 1.75 to 3.39; P < .0001) and 2.44 (95% CI &#61; 1.73 to 3.46; P < .0001) for the implant failure at patient level and implant level, respectively. The comparisons presented a low heterogeneity for the patient-level analysis and a moderate heterogeneity for the implant-level analysis among the pooled studies. Subgroup analyses also revealed that patients who received only selective serotonin reuptake inhibitors (SSRIs) or SSRIs with other types of antidepressants had a higher risk of implant failure than those who were not on any antidepressants.</p><p><strong>Conclusions: </strong>The current review demonstrates that the use of antidepressants such as SSRIs may increase the risk of dental implant failure at both patient level and implant level. Although limited evidence suggests that a certain type of SSRI (sertraline) may have more influence on implant failure than other SSRIs, future studies are needed to confirm this finding.</p>","PeriodicalId":94230,"journal":{"name":"The International journal of oral & maxillofacial implants","volume":"0 0","pages":"665-673"},"PeriodicalIF":0.0,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140159813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immediate Versus Non-immediate Loading Protocols for Reduced-Diameter Implants Supporting Overdentures: A Systematic Review and Meta-analysis.","authors":"Ying Liu, Fengxiao He, Yaoyu Zhao, Quan Sun, Haibin Xia, Dahong Xia, Yi Bai","doi":"10.11607/jomi.10625","DOIUrl":"10.11607/jomi.10625","url":null,"abstract":"<p><strong>Purpose: </strong>To compare the influence of immediate loading (IL) and non-immediate loading (NIL) protocols on overdentures retained by reduced-diameter implants (≤ 3.5 mm).</p><p><strong>Materials and methods: </strong>Electronic databases including MEDLINE (via PubMed), Embase, and the Cochrane Central Register of Controlled Trials were searched for randomized controlled trials (RCTs) comparing clinical outcomes of immediately loaded and non-immediately loaded reduced-diameter implants supporting overdentures. The risk of bias within and across the studies and the certainty of evidence were assessed by RoB 2.0 and GRADE, respectively. A sensitivity analysis was performed by eliminating studies at high risk of bias and repeating the data synthesis employing the random effects model. Subgroup analyses were conducted based on the implant diameter and the length of follow-up.</p><p><strong>Results: </strong>Overall, six RCTs with 255 patients were included in this systematic review. The meta-analyses found similar implant survival rates between immediately loaded and non-immediately loaded implants in the mini-implant (RR &#61; 0.98; 95% CI &#61; 0.95, 1.01; P &#61; .12) and narrow-diameter implant subgroups (RR &#61; 0.99; 95% CI &#61; 0.94, 1.03; P &#61; .56) as well as in short-term (RR &#61; 0.98; 95% CI &#61; 0.97, 1.00; P &#61; .11) and long-term (RR &#61; 0.97; 95% CI &#61; 0.93, 1.01; P &#61; .09) follow-up subgroups. Additionally, marginal bone loss (MBL) showed no statistically significant difference between the loading protocols in the subgroup of long-term follow-up (MD &#61; 0.03; 95% CI &#61; -0.16, 0.23; P &#61; .74). Three RCTs investigating peri-implant parameters found relatively higher modified plaque index (PI) and probing depth (PD) in reduced-diameter implants under IL.</p><p><strong>Conclusions: </strong>Compared with NIL, the IL protocol can achieve comparable survival rates and MBL in reduced-diameter implants supporting overdentures.</p>","PeriodicalId":94230,"journal":{"name":"The International journal of oral & maxillofacial implants","volume":"0 0","pages":"657-664"},"PeriodicalIF":0.0,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140159869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Change in the Spatial Position of Mini-implants During Distal Movement of the Entire Maxillary Dentition: An Observational CBCT Study.","authors":"A Sumathi Felicita, T N Uma Maheshwari","doi":"10.11607/jomi.10789","DOIUrl":"10.11607/jomi.10789","url":null,"abstract":"<p><strong>Purpose: </strong>To determine the change in the sagittal and vertical position of mini-implants placed in the maxilla during distal movement of the entire maxillary dentition.</p><p><strong>Materials and methods: </strong>Overall, 28 mini-implants (1 placed on each side in 14 patients) were evaluated in healthy patients aged 15 to 25 years old. CBCTs were taken immediately after leveling and aligning prior to distalization (T1) and after 6 months (T2) to evaluate the distal movement of the maxillary teeth and position of the mini-implants. The vertical and sagittal angulation of each mini-implant was measured at T1 and T2. The linear distance between the mini-implant and the alveolar crest, the maxillary sinus, the maxillary second premolar, and the maxillary first permanent molar were measured. The change in angulation and the linear displacement of the miniimplant were evaluated in the vertical and sagittal plane. Wilcoxon signed rank test was performed to determine if there was a statistically significant change in the position of the mini-implant.</p><p><strong>Results: </strong>Vertically, there was a significant change in the linear distance between the mini-implant and the alveolar crest on the right side (P ≤ .006) as well as the miniimplant and the maxillary sinus on the left side (P ≤ .003). Sagittally, there was a statistically significant rotation of the miniimplant occlusally (left side P ≤ .004 and right side P ≤ .002). The head and tip of the mini-implant were displaced toward the maxillary second premolar and away from the maxillary first permanent molar, respectively. There was a significant relative displacement of the mini-implant anteriorly away from the maxillary first permanent molar (left side P ≤ .026 and right side P ≤ .041) and closer to the maxillary second premolar (left side: P ≤ .011 and right side: P ≤ .002).</p><p><strong>Conclusions: </strong>There was a statistically and clinically significant rotation of the mini-implant in the vertical and sagittal direction during distal movement of the entire maxillary arch. The linear displacement of the mini-implant was more pronounced in the sagittal direction than the vertical direction.</p>","PeriodicalId":94230,"journal":{"name":"The International journal of oral & maxillofacial implants","volume":"0 0","pages":"183-192"},"PeriodicalIF":0.0,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140878278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New Bone Growth into Surgical Bone Defects Grafted with a Novel Cultivated Coral Graft: A Histomorphometric Study in Rabbit Calvarias.","authors":"Haim Tal, Omer Cohen, Fatma Rayyan, Ariel Pokhojaev, Rachel Sarig, Perry Raz, Ilan Beitlitum","doi":"10.11607/jomi.10703","DOIUrl":"10.11607/jomi.10703","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate a new cultivated coral graft (CCG) in an in vivo experimental guided bone regeneration (GBR) procedure.</p><p><strong>Materials and methods: </strong>The calvarias of eight rabbits were surgically exposed, and circular defects 8 mm in diameter were prepared. One defect was filled with CCG particles (experimental group); the contralateral defect (control group) was spontaneously filled by blood clot. All defects were covered with a collagen membrane. Subjects were euthanized after 8 weeks.</p><p><strong>Results: </strong>Histologic observations of the defects showed similar bone growth patterns in both experimental and control osteotomies. In the experimental defects, no traces of coral particles were observed. Histometric analysis showed denser bone in the pristine zone (65%-66%) than in the peripheral zone for both the control (50%) and experimental defects (31%) (P &#61; not significant). The new bone percentage was reduced from the peripheral zone toward the middle and the center of the defect (31%, 32%, and 27%, respectively) as the distance from the peripheral pristine bone borders increased.</p><p><strong>Conclusions: </strong>The existing data supports the complete degradation of CCG as a spacemaintaining scaffold for GBR procedures.</p>","PeriodicalId":94230,"journal":{"name":"The International journal of oral & maxillofacial implants","volume":"0 0","pages":"723-730"},"PeriodicalIF":0.0,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139522038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}