Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia最新文献_第7页

Corrigendum to "A rapid surveillance of pneumonia in hospitalized patients: an opportunity for intervention". “住院患者肺炎的快速监测：干预的机会”的勘误表。

IF 2.2

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia Pub Date : 2026-01-01 DOI: 10.37201/req/243.2026

引用次数: 0

[Pneumococcal meningitis in a tertiary care hospital: clinical characteristics, serotype distribution, and vaccination status]. [高复杂性医院的肺炎球菌脑膜炎：临床特征、血清型分布和疫苗接种状况]

IF 2.2

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia Pub Date : 2025-12-03 DOI: 10.37201/req/090.2025

Carol Ingrid Castellares-González, Juan Carlos Sanz-Moreno, Ana Isabel Garrido-Buenache, Pilar Arrazola-Martínez, Sara de-Miguel-García

{"title":"[Pneumococcal meningitis in a tertiary care hospital: clinical characteristics, serotype distribution, and vaccination status].","authors":"Carol Ingrid Castellares-González, Juan Carlos Sanz-Moreno, Ana Isabel Garrido-Buenache, Pilar Arrazola-Martínez, Sara de-Miguel-García","doi":"10.37201/req/090.2025","DOIUrl":"10.37201/req/090.2025","url":null,"abstract":"Introduction: Pneumococcal meningitis is a severe form of invasive pneumococcal disease (IPD). Despite the changes introduced by conjugate vaccines, pneumococcal meningitis remains a major clinical and public health challenge. Analyzing its current patterns allows the identification of serotypes that retain a higher invasive potential, the assessment of their relationship with clinical outcomes, and the guidance of future preventive strategies.Methods: Retrospective descriptive study of patients with pneumococcal meningitis admitted between 2018 and 2024. Clinical, demographic, and microbiological variables were analyzed, including identified serotypes, markers of severity (ICU, intubation, death), vaccination status, and antimicrobial sensitivity.Results: Thirty-six cases of pneumococcal meningitis were identified (8 pediatric, 28 adults), with a case fatality rate of 19.4% and an ICU admission rate of 69.4%. The serotype was identified in 88.9% of cases, with 17 different serotypes detected. The most aggressive serotypes were 8, 3, 16, 33, and 23B, and the most lethal were 8, 3, 23A, 25A, and 9N. Seventy-five percent of adults had an indication for vaccination, but only half had received any doses. Resistance to cefotaxime was documented in three strains (9N, 19A, 23F), one of which was associated with a fatal outcome.Conclusion: Pneumococcal meningitis remains a serious condition. Serotypes such as 8 and 3 are associated with high mortality rates. Low vaccination coverage in at-risk groups represents a critical gap in prevention. Knowing the serotypes involved and their resistance profiles is key to adapting vaccination strategies and reducing the burden of this disease.","PeriodicalId":94198,"journal":{"name":"Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia","volume":" ","pages":"495-503"},"PeriodicalIF":2.2,"publicationDate":"2025-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12707434/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145673082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Endocarditis due to Coxiella burnetii in congenital heart disease patients: a clinical case series and diagnostic considerations. 先天性心脏病患者由伯纳蒂克希菌引起的心内膜炎：临床病例系列和诊断考虑

IF 2.2

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia Pub Date : 2025-12-03 DOI: 10.37201/req/074.2025

José Manuel Puyana-Rodríguez, Mercedes Guida-Piqueras, Enrique Navas-Elorza, Isabel Molina-Borao, Natalia Rivero-Jiménez, María Elvira Garrido-Lestache Rodríguez-Monte, Jesús Fortún-Abete, María Jesús Del-Cerro-Marín, María Álvarez-Fuente

引用次数: 0

Neoscytalidium dimidiatum: a rare locally acquired deep cutaneous infection in a renal transplant recipient. 肾移植受者罕见的局部获得性深部皮肤感染。

IF 2.2

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia Pub Date : 2025-12-03 DOI: 10.37201/req/064.2025

Laudy Rivero-Rodríguez, Daniel Adrados-Ruiz, Andrea San-José-Rodríguez, Julio Orlando Rodríguez-López

引用次数: 0

[Beyond the puncture site: discordance between ventricular and lumbar CSF in paediatric tuberculous meningitis]. [穿刺部位以外：儿科结核性脑膜炎中心室-腰椎CRL不匹配]。

IF 2.2

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia Pub Date : 2025-12-03 DOI: 10.37201/req/091.2025

José Iván Castillo-Bejarano, Paul Santiago Arcos-Viscarra, Marcela Lizeth Morales-López, Denisse Natalie Vaquera-Aparicio, Abiel Homero Mascareñas-de-Los-Santos

引用次数: 0

A clinically relevant reinterpretation of disk approximation testing for inducible AmpC in Pseudomonas aeruginosa. 铜绿假单胞菌诱导型AmpC的圆盘近似试验的临床意义。

IF 2.2

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia Pub Date : 2025-11-21 DOI: 10.37201/req/089.2025

Arturo Reyes-Gualito, Luis Raúl Rivera-Garay, Azyadeh Cobo-Alva, María José Orozco-Uriarte, Alejandro E Macías, José Antonio Álvarez-Canales

{"title":"A clinically relevant reinterpretation of disk approximation testing for inducible AmpC in Pseudomonas aeruginosa.","authors":"Arturo Reyes-Gualito, Luis Raúl Rivera-Garay, Azyadeh Cobo-Alva, María José Orozco-Uriarte, Alejandro E Macías, José Antonio Álvarez-Canales","doi":"10.37201/req/089.2025","DOIUrl":"10.37201/req/089.2025","url":null,"abstract":"Introduction: Current antimicrobial susceptibility methods fail to capture the variability of AmpC induction pathways in Pseudomonas aeruginosa. This leads to preventable errors in ceftazidime susceptibility reporting. We introduce a reinterpretation for the disk approximation test, based on the categorical change in ceftazidime susceptibility upon imipenem exposure.Materials and methods: A total of 73 ceftazidime-susceptible P. aeruginosa isolates were evaluated. Automated broth microdilution test was the reference standard. AmpC inducibility was conventionally defined as a ≥5 mm flattening of the ceftazidime inhibition zone adjacent to imipenem. Our novel criterion for inducibility was a change in ceftazidime category from susceptible to nonsusceptible. The probability of error in ceftazidime reporting was evaluated with three parameters. ROC curve, comparative and regression analyses were performed.Results: The reference method showed an overall error probability of 35.6%. The conventional 5 mm cutoff interpretation reduced this rate to 5.4%, but generated a significant proportion of false positives and negatives. Regression analyses showed that the flattening effect is a strong predictor of the categorical change. No association was found between basal ceftazidime susceptibility and AmpC inducibility.Conclusion: Our reinterpretation criterion for disk approximation test turns a phenotypic assay into a clinically relevant diagnostic tool to avoid errors in ceftazidime susceptibility reports. Moreover, this interpretation is readily applicable in routine microbiology laboratories, and has the potential to be directly useful for antimicrobial stewardship efforts.","PeriodicalId":94198,"journal":{"name":"Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia","volume":" ","pages":"485-494"},"PeriodicalIF":2.2,"publicationDate":"2025-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12707433/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145644199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Spontaneous bacterial peritonitis due to Brucella species versus peritoneal dialysis-related peritonitis: a systematic review. 由布鲁氏菌引起的自发性细菌性腹膜炎与腹膜透析相关的腹膜炎：一项系统综述。

IF 2.2

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia Pub Date : 2025-11-21 DOI: 10.37201/req/075.2025

John Dotis, Charalampos Antachopoulos, Athina Papadopoulou, Nikoleta Printza

{"title":"Spontaneous bacterial peritonitis due to Brucella species versus peritoneal dialysis-related peritonitis: a systematic review.","authors":"John Dotis, Charalampos Antachopoulos, Athina Papadopoulou, Nikoleta Printza","doi":"10.37201/req/075.2025","DOIUrl":"10.37201/req/075.2025","url":null,"abstract":"Introduction: Brucella-associated primary peritonitis is an exceptionally rare condition that may present as spontaneous bacterial peritonitis (SBP) or peritoneal dialysis-related peritonitis (PDrP). We investigated demographic and clinical characteristics of these two entities caused by Brucella species.Methods: A systematic review of the literature was undertaken to identify published cases of primary peritonitis caused by Brucella species and perform comparative analysis. Cases were categorized as SBP or PDrP and analyzed for demographics, clinical features, microbiology, treatment regimens and outcomes.Results: A total of 33 cases were identified: 22 of SBP and 11 of PDrP. Among these, SBP cases occurred predominantly in older cirrhotic males (mean age 55.2 years), with Brucella isolated mainly from blood cultures (72.7%) and an associated mortality rate of 13.6%. In contrast, PDrP cases involved younger, generally healthier individuals on PD (mean age 47.5 years), where Brucella was universally isolated from peritoneal fluid and mortality was 0%. Catheter removal was required in 36.4% of PDrP cases. Epidemiological risk factors were more common in PDrP (81.8% vs. 45.5%). Blood culture positivity was significantly higher in SBP (p=0.016), while peritoneal fluid cultures were more often diagnostic in PDrP (p=0.028). Most patients received combination therapy with doxycycline and rifampicin, while treatment duration tended to be longer in PDrP.Conclusion: Brucella peritonitis shows differing patterns in SBP and PDrP. Early identification and appropriate intervention are essential for favorable clinical results.","PeriodicalId":94198,"journal":{"name":"Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia","volume":" ","pages":"471-484"},"PeriodicalIF":2.2,"publicationDate":"2025-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12707342/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145644201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[From rhinorrhea to 16S: meningitis caused by Streptococcus salivarius]. [从鼻臭到16S：唾液链球菌脑膜炎]。

IF 2.2

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia Pub Date : 2025-11-21 DOI: 10.37201/req/072.2025

Belén Cuadrado-García, Beatriz Castro-Hernández, Elene Laburu-Dañobeitia, María Gabriela Muñoz-Cordero, María Lecuona-Fernández

引用次数: 0

[Primary conjunctivitis caused by Neisseria meningitidis in an adult contact lens wearer]. [戴隐形眼镜成人原发性脑膜炎奈瑟菌结膜炎]。

IF 2.2

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia Pub Date : 2025-11-21 DOI: 10.37201/req/068.2025

María Ternero-Piña, Margarita Bolaños-Rivero, Michele Hernández-Cabrera, Isabel de-Miguel-Martínez

引用次数: 0

Causes and consequences of undervaccination in adults. 成人疫苗接种不足的原因和后果。

IF 2.2

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia Pub Date : 2025-11-11 DOI: 10.37201/req/106.2025

Ángel Gil-de-Miguel, José Antonio Navarro-Alonso, María Pilar Arrazola-Martínez, David Cantarero, Manuel Arellano, Alejandro Cremades-Bernabéu, María Fernández-Prada, Ruth Gil-Prieto, Diego Gracia, Elena Martínez-Palancar, Jaime Jesús Pérez-Martín, Esther Redondo-Margüello, Nieves Sebastián, Natividad Tolosa-Martínez, Emilio Bouza

{"title":"Causes and consequences of undervaccination in adults.","authors":"Ángel Gil-de-Miguel, José Antonio Navarro-Alonso, María Pilar Arrazola-Martínez, David Cantarero, Manuel Arellano, Alejandro Cremades-Bernabéu, María Fernández-Prada, Ruth Gil-Prieto, Diego Gracia, Elena Martínez-Palancar, Jaime Jesús Pérez-Martín, Esther Redondo-Margüello, Nieves Sebastián, Natividad Tolosa-Martínez, Emilio Bouza","doi":"10.37201/req/106.2025","DOIUrl":"10.37201/req/106.2025","url":null,"abstract":"Despite progress in adult vaccination schedules, coverage rates remain suboptimal in Spain. This opinion paper, authored by a multidisciplinary group of experts, analyzes the causes and consequences of adult undervaccination, covering clinical, social, economic, and ethical aspects. Over 10 million individuals aged 65+ are targeted for vaccination, along with adults with chronic illnesses. However, coverage remains low, with significant disparities across vaccines, regions, and risk groups. The causes of the \"vaccination gap\" include lack of training among healthcare professionals, organizational barriers, misinformation, low-risk perception among the public, and weak institutional engagement. This situation leads to increased morbidity, mortality, and avoidable costs for the healthcare system. Universal adult vaccination could significantly reduce these burdens. The document outlines structured solutions: targeted professional training, multicomponent strategies, centralized vaccination registries, effective public awareness campaigns, improved access, and integration of vaccination across all healthcare levels. The key role of healthcare workers, patient organizations, and the media is emphasized in improving vaccination coverage.","PeriodicalId":94198,"journal":{"name":"Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia","volume":" ","pages":"1-29"},"PeriodicalIF":2.2,"publicationDate":"2025-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12935086/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145514698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0