Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia最新文献

{"title":"[Epidemiological, clinical, and diagnostic analysis of an outbreak of Parvovirus B19 infection in Mallorca Island].","authors":"Jordi Reina, Pablo Fraile-Ribot, Julia Viana-Ramírez, Loreto Suárez, Olivia Gutiérrez","doi":"10.37201/req/004.2025","DOIUrl":"10.37201/req/004.2025","url":null,"abstract":"<p><strong>Introduction: </strong>An observational study is presented on a community outbreak of parvovirus B19 (PVB19) infection that occurred between January and July 2024 in Mallorca.</p><p><strong>Methods: </strong>PVB19 infection was diagnosed by serology (IgM) and specific PCR.</p><p><strong>Results: </strong>A total of 151 patients were diagnosed. Of these, 63 (41.7%) were <15 years old. The age groups with the highest number of cases were 5-10 years (19.8%) and 30-45 years (33.7%). Overall, 33.1% were male and 66.9% female, with age-related differences; among adults, 81.9% were female. The most frequent pathologies in the child population were fever, rash and petechiae, while in adults, fever and arthralgia predominated. Among the women, 8 were pregnant (11.1%) and 4 had fetal involvement. In addition to serum, PVB19 was detected in 10 pharyngeal swabs, 6 skin swabs, 3 cerebrospinal fluid (CSF) samples, and 1 amniotic fluid sample. Specific IgM was detected in 98.4% of cases, along with cross-reactions with Epstein-Barr virus (69.5%) and mumps virus (42.8%), mainly in adults. In 6 cases, positive IgM was detected to PVB19, Epstein-Barr virus and mumps were simultaneously detected (4 adults and 2 children). PCR was positive in 95.4% of all samples and in 94.6% of serum samples.</p><p><strong>Conclusions: </strong>The specific diagnosis of PVB19 infection should be based not only on clinical findings but also on serological detection (IgM) and genomic detection (PCR).</p>","PeriodicalId":94198,"journal":{"name":"Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia","volume":"38 3","pages":"214-221"},"PeriodicalIF":0.0,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12095931/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144053130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Four cases of bacteremia caused by <i>Enterocloster clostridioformis</i>.","authors":"Fernando Cobo, Javier Rodríguez-Granger, José María Navarro-Mari, Rafael Ceballos-Atienza, Antonio Sampedro-Martínez, Juan Antonio Reguera-Márquez","doi":"10.37201/req/021.2025","DOIUrl":"10.37201/req/021.2025","url":null,"abstract":"","PeriodicalId":94198,"journal":{"name":"Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia","volume":"38 3","pages":"255-257"},"PeriodicalIF":0.0,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12095929/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144047078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anemia and lower limbs edemas in a patient with HIV infection.","authors":"Francisco Arnaiz de Las Revillas, Javier Martín-López, Milagros Heras-Vicario, Montserrat Briz Del Blanco, Carlos Armiñanzas-Castillo, Manuel Gutiérrez-Cuadra, Paula Runza-Buznego, Raul Parra-Fariñas, María Carmen Fariñas-Álvarez","doi":"10.37201/req/124.2024","DOIUrl":"10.37201/req/124.2024","url":null,"abstract":"","PeriodicalId":94198,"journal":{"name":"Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia","volume":"38 3","pages":"244-248"},"PeriodicalIF":0.0,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12095933/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143797557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of a multifaceted intervention on potentially unnecessary antibiotic prescriptions in general practice, out-of-hours services, and nursing homes in Spain.","authors":"Ana García-Sangenís, Fabiana Raynal-Floriano, Beatriz González López-Valcárcel, Laura Vallejo-Torres, Carl Llor","doi":"10.37201/req/024.2025","DOIUrl":"10.37201/req/024.2025","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the impact of a multifaceted antimicrobial stewardship intervention on potentially unnecessary antibiotic prescribing.</p><p><strong>Material and methods: </strong>Before and after quality control study carried out in three different settingsgeneral practice, out-of-hours services, and nursing homesin Spain. Healthcare professionals (both doctors and nurses) self-registered common infections using a specific template for each setting before (2022) and after (2023) receiving a 5-hour intervention on prudent antibiotic use.</p><p><strong>Results: </strong>Eighty-nine professionals participated in the first registration (48 in general practice, 23 in out-of-hours services, and 15 in nursing homes), with 71 (79.8%) completing the intervention and second registration. Potentially unnecessary antibiotic prescriptions were 68.5%, 41.7%, and 77.7% in the first registration, respectively, and 61.4%, 34.8%, and 86.8% after the intervention, showing reductions of 10.4% in general practice and 16.5% in out-of-hours services, and an 11.7% increase in nursing homes, albeit without statistically significant differences.</p><p><strong>Conclusions: </strong>The study found that this intervention slightly improved antibiotic use, with minimal impact, but worsened in nursing homes.</p>","PeriodicalId":94198,"journal":{"name":"Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia","volume":"38 3","pages":"234-239"},"PeriodicalIF":0.0,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12095936/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143723057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Towards a holistic approach to pulmonary infections. Insights from the Sixth Annual Meeting of Spanish Experts 2024.","authors":"Cristobal M Rodriguez-Leal, Carlos González-Corralejo, Francisco Javier Candel, Miguel Salavert","doi":"10.37201/req/017.2025","DOIUrl":"10.37201/req/017.2025","url":null,"abstract":"<p><p>Pneumonia is the leading cause of death from infection in the developed world. In recent years, researchers and healthcare professionals have worked extensively to reduce this burden. Prevention is better than cure, and significant advances have been made in areas such as vaccination and the prevention of nosocomial pneumonia in intensive care units. Comprehensive surveillance programmes and new diagnostic methods have been developed to assess trends in this disease and to identify the infectious agents involved. Clinical presentation can be challenging in elderly patients or those with certain comorbidities, prompting new studies in these populations to address these issues. Correct and early management of severe community-acquired pneumonia represents a major opportunity to reduce its associated mortality. Although fungal pathogens are an uncommon cause of lung infection, they are associated with high morbidity and mortality, highlighting the need for new approaches. Finally, new drugs are available for the treatment of pneumonia, and a thorough understanding of them is key to ensuring their correct use, particularly to combat multi-resistance. To provide an update on these points, a multidisciplinary team of Spanish experts convened at the Sixth Annual Meeting of Pneumonia Day, under the scientific sponsorship of GEIPC-SEIMC. This paper reflects the information shared at this meeting, offering the latest insights on these topics and supporting a holistic approach to pneumonia management.</p>","PeriodicalId":94198,"journal":{"name":"Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia","volume":"38 3","pages":"152-186"},"PeriodicalIF":0.0,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12095940/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143723058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Azole-resistant <i>Candida parapsilosis</i> in Critical Care Units].","authors":"Nerea Antona-Urieta, Jose L Barrios-Andrés, Iratxe Seijas-Betolaza, Juan Higuera-Lucas, Victoria Boado-Varela, Elena López-Peralta, Laura Alcázar-Fuoli, Oscar Zaragoza-Hernández, Leyre M López-Soria","doi":"10.37201/req/122.2024","DOIUrl":"10.37201/req/122.2024","url":null,"abstract":"","PeriodicalId":94198,"journal":{"name":"Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia","volume":"38 3","pages":"240-243"},"PeriodicalIF":0.0,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12095932/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143695039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Whooping cough outbreak in 2024. New distribution pattern in contagion? Should the booster doses in vaccination be reconsidered?]","authors":"Pablo Ávila-Franco, Marta Domínguez-Gil González, Lucía Puente-Fuertes, José M Eiros","doi":"10.37201/req/102.2024","DOIUrl":"10.37201/req/102.2024","url":null,"abstract":"","PeriodicalId":94198,"journal":{"name":"Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia","volume":"38 2","pages":"133-135"},"PeriodicalIF":0.0,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11894564/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143416407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Mastitis caused by <i>Streptococcus pneumoniae</i>: presentation of 3 cases and literature review].","authors":"Marta Cascajero, Daniel Tena","doi":"10.37201/req/105.2024","DOIUrl":"10.37201/req/105.2024","url":null,"abstract":"","PeriodicalId":94198,"journal":{"name":"Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia","volume":"38 2","pages":"136-138"},"PeriodicalIF":0.0,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11894560/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143384606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Relevance of genetic polymorphisms in voriconazole neurotoxicity: case report in a pediatric patient].","authors":"Alicia Martín-Roldán, Alejandra Merino-Pardo, Esther Algarra-Sánchez, Margarita Cuervas-Mons Vendrell","doi":"10.37201/req/112.2024","DOIUrl":"10.37201/req/112.2024","url":null,"abstract":"","PeriodicalId":94198,"journal":{"name":"Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia","volume":"38 2","pages":"145-147"},"PeriodicalIF":0.0,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11894559/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143470400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Emergent presence of slow-growing microorganisms in urine cultures. Clinical and microbiological analysis].","authors":"Leticia Castellano-Sánchez, Antonio Rosales-Castillo, María Carmen Olvera-Porcel, José María Navarro-Marí, José Gutiérrez-Fernández","doi":"10.37201/req/101.2024","DOIUrl":"10.37201/req/101.2024","url":null,"abstract":"<p><strong>Introduction: </strong>The prevalence, clinical characteristics, and antibiotic susceptibility of the slow-growing microorganisms <i>Corynebacterium urealyticum, Corynebacterium glucuronolyticum, Lactobacillus delbrueckii</i>, and <i>Aerococcus</i> spp. in urine cultures are analyzed.</p><p><strong>Material and methods: </strong>Descriptive and retrospective cross-sectional study carried out in a Regional Hospital. Reports of clinical episodes with single isolation of the aforementioned microorganisms were selected between January 2016 and December 2023.</p><p><strong>Results: </strong>A total of 186 single-isolation episodes were included, corresponding to 0.44% of the total. The most frequently isolated species was <i>Aerococcus urinae</i>. Overall, the risk factors were the presence of an indwelling bladder catheter (24.73%), immunosuppression (24.19%), health care (35.48%), diabetes mellitus (19.89%), nephrourological disorders (31.18%) and previous antibiotherapy (35.48%). Urinary tract infections due to <i>Aerococcus</i> spp. predominated in elderly patients, with nephrourological disorders and a history of antibiotic therapy in the previous 3 months. <i>C. glucuronolyticum, C. urealyticum</i> and <i>L. delbrueckii</i> were associated with immunosuppression, healthcare contact and previous antibiotherapy. <i>C. urealyticum</i> was also associated with the presence of an indwelling bladder catheter.</p><p><strong>Conclusions: </strong>Slow-growing opportunistic emerging microorganisms represent a small percentage of the aetiological agents in urinary tract infections, although of important and growing clinical interest given their pathogenic role in the presence of certain circumstances and risk factors, as well as the challenges they pose for laboratory diagnosis. It is essential to perform antibiograms for an adequate targeted treatment.</p>","PeriodicalId":94198,"journal":{"name":"Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia","volume":"38 2","pages":"75-83"},"PeriodicalIF":0.0,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11894568/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143384592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}