Neurological research and practice最新文献

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Recovery of intracranial stenoses in varicella zoster virus vasculitis after long-term treatment with valacyclovir and prednisolone 缬昔洛韦和泼尼松长期治疗水痘带状疱疹病毒性血管炎后颅内狭窄的恢复
Neurological research and practice Pub Date : 2022-05-16 DOI: 10.1186/s42466-022-00180-1
M. Kraemer, D. Strunk, Jana Becker, R. Veltkamp, P. Berlit
{"title":"Recovery of intracranial stenoses in varicella zoster virus vasculitis after long-term treatment with valacyclovir and prednisolone","authors":"M. Kraemer, D. Strunk, Jana Becker, R. Veltkamp, P. Berlit","doi":"10.1186/s42466-022-00180-1","DOIUrl":"https://doi.org/10.1186/s42466-022-00180-1","url":null,"abstract":"","PeriodicalId":94156,"journal":{"name":"Neurological research and practice","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46558144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Residents as teachers in Neurology: a Germany-wide survey on the involvement of neurological residents in clinical teaching 神经内科住院医师作为教师:一项德国范围内关于神经内科住院医师参与临床教学的调查
Neurological research and practice Pub Date : 2022-05-09 DOI: 10.1186/s42466-022-00170-3
Anne-Sophie Biesalski, L. Tönges, Isabelle von Kirchbauer, Eileen Gülke, Hanna Eisenberg, F. Ippen, F. Schmidt-Graf
{"title":"Residents as teachers in Neurology: a Germany-wide survey on the involvement of neurological residents in clinical teaching","authors":"Anne-Sophie Biesalski, L. Tönges, Isabelle von Kirchbauer, Eileen Gülke, Hanna Eisenberg, F. Ippen, F. Schmidt-Graf","doi":"10.1186/s42466-022-00170-3","DOIUrl":"https://doi.org/10.1186/s42466-022-00170-3","url":null,"abstract":"","PeriodicalId":94156,"journal":{"name":"Neurological research and practice","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43712625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intracranial bleeding under vitamin K antagonists or direct oral anticoagulants: results of the RADOA registry 服用维生素K拮抗剂或直接口服抗凝剂后颅内出血:RADOA登记结果
Neurological research and practice Pub Date : 2022-05-02 DOI: 10.1186/s42466-022-00183-y
W. Pfeilschifter, E. Lindhoff-Last, Ali Alhashim, Barbara Zydek, S. Lindau, S. Konstantinides, O. Grottke, U. Nowak‐Göttl, C. von Heymann, I. Birschmann, J. Beyer-Westendorf, P. Meybohm, A. Greinacher, E. Herrmann
{"title":"Intracranial bleeding under vitamin K antagonists or direct oral anticoagulants: results of the RADOA registry","authors":"W. Pfeilschifter, E. Lindhoff-Last, Ali Alhashim, Barbara Zydek, S. Lindau, S. Konstantinides, O. Grottke, U. Nowak‐Göttl, C. von Heymann, I. Birschmann, J. Beyer-Westendorf, P. Meybohm, A. Greinacher, E. Herrmann","doi":"10.1186/s42466-022-00183-y","DOIUrl":"https://doi.org/10.1186/s42466-022-00183-y","url":null,"abstract":"","PeriodicalId":94156,"journal":{"name":"Neurological research and practice","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43294830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
On the quest for hidden ovarian teratomas in therapy-refractory anti-NMDA receptor encephalitis: a case report 在治疗难治性抗nmda受体脑炎中寻找隐藏的卵巢畸胎瘤:1例报告
Neurological research and practice Pub Date : 2022-04-25 DOI: 10.1186/s42466-022-00181-0
C. Cirkel, Anna Cirkel, G. Royl, A. Frydrychowicz, L. Tharun, S. Deichmann, A. Rody, T. Münte, B. Machner
{"title":"On the quest for hidden ovarian teratomas in therapy-refractory anti-NMDA receptor encephalitis: a case report","authors":"C. Cirkel, Anna Cirkel, G. Royl, A. Frydrychowicz, L. Tharun, S. Deichmann, A. Rody, T. Münte, B. Machner","doi":"10.1186/s42466-022-00181-0","DOIUrl":"https://doi.org/10.1186/s42466-022-00181-0","url":null,"abstract":"","PeriodicalId":94156,"journal":{"name":"Neurological research and practice","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46035472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
A mobile battery-powered brain perfusion ultrasound (BPU) device designed for prehospital stroke diagnosis: correlation to perfusion MRI in healthy volunteers. 设计用于院前中风诊断的移动电池供电脑灌注超声(BPU)设备:与健康志愿者灌注MRI的相关性
Neurological research and practice Pub Date : 2022-04-11 DOI: 10.1186/s42466-022-00179-8
Mustafa Kilic, Fabien Scalzo, Chandler Lyle, Dobri Baldaranov, Maximilian Dirnbacher, Tristan Honda, David S Liebeskind, Felix Schlachetzki
{"title":"A mobile battery-powered brain perfusion ultrasound (BPU) device designed for prehospital stroke diagnosis: correlation to perfusion MRI in healthy volunteers.","authors":"Mustafa Kilic, Fabien Scalzo, Chandler Lyle, Dobri Baldaranov, Maximilian Dirnbacher, Tristan Honda, David S Liebeskind, Felix Schlachetzki","doi":"10.1186/s42466-022-00179-8","DOIUrl":"10.1186/s42466-022-00179-8","url":null,"abstract":"<p><strong>Background: </strong>Early prehospital stroke identification is crucial for goal directed hospital admission especially in rural areas. However, clinical prehospital stroke scales are designed to identify any stroke but cannot sufficiently differentiate hemorrhagic from ischemic stroke, including large vessel occlusion (LVO) amenable to mechanical thrombectomy. We report on a novel small, portable and battery driven point-of-care ultrasound system (SONAS®) specifically developed for mobile non-invasive brain perfusion ultrasound (BPU) measurement after bolus injection of an echo-enhancing agent suitable for the use in prehospital stroke diagnosis filling a current, unmet and critical need for LVO identification.</p><p><strong>Methods: </strong>In a phase I study of healthy volunteers we performed comparative perfusion-weighted magnetic resonance imaging (PWI) and BPU measurements, including safety analysis.</p><p><strong>Results: </strong>Twelve volunteers (n = 7 females, n = 5 males, age ranging between 19 and 55 years) tolerated the measurement extremely well including analysis of blood-brain barrier integrity, and the correlation coefficient between the generated time kinetic curves after contrast agent bolus between PWI and BPU transducers ranged between 0.89 and 0.76.</p><p><strong>Conclusions: </strong>Mobile BPU using the SONAS® device is feasible and safe with results comparable to PWI. When applied in conjunction with prehospital stroke scales this may lead to a more accurate stroke diagnosis and patients bypassing regular stroke units to comprehensive stroke centers. Further studies are needed in acute stroke patients and in the prehospital phase including assessment of immediate and long-term morbidity and mortality in stroke.</p><p><strong>Trial registration: </strong>Clinical trials.gov, registered 28.Sep.2017, Identifier: NCT03296852.</p>","PeriodicalId":94156,"journal":{"name":"Neurological research and practice","volume":" ","pages":"13"},"PeriodicalIF":0.0,"publicationDate":"2022-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996400/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45868567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transcranial Doppler sonography and the effect of haematopoietic stem cell transplantation in sickle cell disease 经颅多普勒超声与造血干细胞移植治疗镰状细胞病的疗效
Neurological research and practice Pub Date : 2022-04-04 DOI: 10.1186/s42466-022-00175-y
Sylvia Thurn, Katharina Kleinschmidt, Irena Kovačič, C. Wendl, R. Linker, S. Corbacioglu, F. Schlachetzki
{"title":"Transcranial Doppler sonography and the effect of haematopoietic stem cell transplantation in sickle cell disease","authors":"Sylvia Thurn, Katharina Kleinschmidt, Irena Kovačič, C. Wendl, R. Linker, S. Corbacioglu, F. Schlachetzki","doi":"10.1186/s42466-022-00175-y","DOIUrl":"https://doi.org/10.1186/s42466-022-00175-y","url":null,"abstract":"","PeriodicalId":94156,"journal":{"name":"Neurological research and practice","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44154626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Polyradiculitis and encephalomyelitis in the same patient following a SARS-CoV-2 vaccination 同一患者在接种SARS-CoV-2疫苗后出现多根炎和脑脊髓炎
Neurological research and practice Pub Date : 2022-03-28 DOI: 10.1186/s42466-022-00177-w
J. Finsterer
{"title":"Polyradiculitis and encephalomyelitis in the same patient following a SARS-CoV-2 vaccination","authors":"J. Finsterer","doi":"10.1186/s42466-022-00177-w","DOIUrl":"https://doi.org/10.1186/s42466-022-00177-w","url":null,"abstract":"","PeriodicalId":94156,"journal":{"name":"Neurological research and practice","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44535495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnosing SARS-CoV-2 vaccination associated rhombencephalitis requires comprehensive work-up and exclusion of differentials 诊断严重急性呼吸系统综合征冠状病毒2型疫苗接种相关菱形脑炎需要全面检查并排除差异
Neurological research and practice Pub Date : 2022-03-21 DOI: 10.1186/s42466-022-00178-9
J. Finsterer, F. Scorza, C. Scorza, A. Fiorini
{"title":"Diagnosing SARS-CoV-2 vaccination associated rhombencephalitis requires comprehensive work-up and exclusion of differentials","authors":"J. Finsterer, F. Scorza, C. Scorza, A. Fiorini","doi":"10.1186/s42466-022-00178-9","DOIUrl":"https://doi.org/10.1186/s42466-022-00178-9","url":null,"abstract":"","PeriodicalId":94156,"journal":{"name":"Neurological research and practice","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45024923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Characterization of advanced Parkinson’s disease in Germany: results of the non-interventional OBSERVE-PD study 德国晚期帕金森病的特征:非介入性OBSERVE-PD研究的结果
Neurological research and practice Pub Date : 2022-03-15 DOI: 10.1186/s42466-022-00176-x
D. Pedrosa, F. Gandor, W. Jost, C. Arlt, Koray Onuk, L. Timmermann
{"title":"Characterization of advanced Parkinson’s disease in Germany: results of the non-interventional OBSERVE-PD study","authors":"D. Pedrosa, F. Gandor, W. Jost, C. Arlt, Koray Onuk, L. Timmermann","doi":"10.1186/s42466-022-00176-x","DOIUrl":"https://doi.org/10.1186/s42466-022-00176-x","url":null,"abstract":"","PeriodicalId":94156,"journal":{"name":"Neurological research and practice","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48235811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Intra-arterial application of nimodipine in reversible cerebral vasoconstriction syndrome: a neuroradiological method to help differentiate from primary central nervous system vasculitis 尼莫地平动脉内应用于可逆性脑血管收缩综合征:一种有助于与原发性中枢神经系统血管炎鉴别的神经放射学方法
Neurological research and practice Pub Date : 2022-02-28 DOI: 10.1186/s42466-022-00173-0
D. Strunk, R. Veltkamp, S. Meuth, R. Chapot, M. Kraemer
{"title":"Intra-arterial application of nimodipine in reversible cerebral vasoconstriction syndrome: a neuroradiological method to help differentiate from primary central nervous system vasculitis","authors":"D. Strunk, R. Veltkamp, S. Meuth, R. Chapot, M. Kraemer","doi":"10.1186/s42466-022-00173-0","DOIUrl":"https://doi.org/10.1186/s42466-022-00173-0","url":null,"abstract":"","PeriodicalId":94156,"journal":{"name":"Neurological research and practice","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48684057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
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