M. Kraemer, D. Strunk, Jana Becker, R. Veltkamp, P. Berlit
{"title":"Recovery of intracranial stenoses in varicella zoster virus vasculitis after long-term treatment with valacyclovir and prednisolone","authors":"M. Kraemer, D. Strunk, Jana Becker, R. Veltkamp, P. Berlit","doi":"10.1186/s42466-022-00180-1","DOIUrl":"https://doi.org/10.1186/s42466-022-00180-1","url":null,"abstract":"","PeriodicalId":94156,"journal":{"name":"Neurological research and practice","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46558144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anne-Sophie Biesalski, L. Tönges, Isabelle von Kirchbauer, Eileen Gülke, Hanna Eisenberg, F. Ippen, F. Schmidt-Graf
{"title":"Residents as teachers in Neurology: a Germany-wide survey on the involvement of neurological residents in clinical teaching","authors":"Anne-Sophie Biesalski, L. Tönges, Isabelle von Kirchbauer, Eileen Gülke, Hanna Eisenberg, F. Ippen, F. Schmidt-Graf","doi":"10.1186/s42466-022-00170-3","DOIUrl":"https://doi.org/10.1186/s42466-022-00170-3","url":null,"abstract":"","PeriodicalId":94156,"journal":{"name":"Neurological research and practice","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43712625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
W. Pfeilschifter, E. Lindhoff-Last, Ali Alhashim, Barbara Zydek, S. Lindau, S. Konstantinides, O. Grottke, U. Nowak‐Göttl, C. von Heymann, I. Birschmann, J. Beyer-Westendorf, P. Meybohm, A. Greinacher, E. Herrmann
{"title":"Intracranial bleeding under vitamin K antagonists or direct oral anticoagulants: results of the RADOA registry","authors":"W. Pfeilschifter, E. Lindhoff-Last, Ali Alhashim, Barbara Zydek, S. Lindau, S. Konstantinides, O. Grottke, U. Nowak‐Göttl, C. von Heymann, I. Birschmann, J. Beyer-Westendorf, P. Meybohm, A. Greinacher, E. Herrmann","doi":"10.1186/s42466-022-00183-y","DOIUrl":"https://doi.org/10.1186/s42466-022-00183-y","url":null,"abstract":"","PeriodicalId":94156,"journal":{"name":"Neurological research and practice","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43294830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Cirkel, Anna Cirkel, G. Royl, A. Frydrychowicz, L. Tharun, S. Deichmann, A. Rody, T. Münte, B. Machner
{"title":"On the quest for hidden ovarian teratomas in therapy-refractory anti-NMDA receptor encephalitis: a case report","authors":"C. Cirkel, Anna Cirkel, G. Royl, A. Frydrychowicz, L. Tharun, S. Deichmann, A. Rody, T. Münte, B. Machner","doi":"10.1186/s42466-022-00181-0","DOIUrl":"https://doi.org/10.1186/s42466-022-00181-0","url":null,"abstract":"","PeriodicalId":94156,"journal":{"name":"Neurological research and practice","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46035472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mustafa Kilic, Fabien Scalzo, Chandler Lyle, Dobri Baldaranov, Maximilian Dirnbacher, Tristan Honda, David S Liebeskind, Felix Schlachetzki
{"title":"A mobile battery-powered brain perfusion ultrasound (BPU) device designed for prehospital stroke diagnosis: correlation to perfusion MRI in healthy volunteers.","authors":"Mustafa Kilic, Fabien Scalzo, Chandler Lyle, Dobri Baldaranov, Maximilian Dirnbacher, Tristan Honda, David S Liebeskind, Felix Schlachetzki","doi":"10.1186/s42466-022-00179-8","DOIUrl":"10.1186/s42466-022-00179-8","url":null,"abstract":"<p><strong>Background: </strong>Early prehospital stroke identification is crucial for goal directed hospital admission especially in rural areas. However, clinical prehospital stroke scales are designed to identify any stroke but cannot sufficiently differentiate hemorrhagic from ischemic stroke, including large vessel occlusion (LVO) amenable to mechanical thrombectomy. We report on a novel small, portable and battery driven point-of-care ultrasound system (SONAS®) specifically developed for mobile non-invasive brain perfusion ultrasound (BPU) measurement after bolus injection of an echo-enhancing agent suitable for the use in prehospital stroke diagnosis filling a current, unmet and critical need for LVO identification.</p><p><strong>Methods: </strong>In a phase I study of healthy volunteers we performed comparative perfusion-weighted magnetic resonance imaging (PWI) and BPU measurements, including safety analysis.</p><p><strong>Results: </strong>Twelve volunteers (n = 7 females, n = 5 males, age ranging between 19 and 55 years) tolerated the measurement extremely well including analysis of blood-brain barrier integrity, and the correlation coefficient between the generated time kinetic curves after contrast agent bolus between PWI and BPU transducers ranged between 0.89 and 0.76.</p><p><strong>Conclusions: </strong>Mobile BPU using the SONAS® device is feasible and safe with results comparable to PWI. When applied in conjunction with prehospital stroke scales this may lead to a more accurate stroke diagnosis and patients bypassing regular stroke units to comprehensive stroke centers. Further studies are needed in acute stroke patients and in the prehospital phase including assessment of immediate and long-term morbidity and mortality in stroke.</p><p><strong>Trial registration: </strong>Clinical trials.gov, registered 28.Sep.2017, Identifier: NCT03296852.</p>","PeriodicalId":94156,"journal":{"name":"Neurological research and practice","volume":" ","pages":"13"},"PeriodicalIF":0.0,"publicationDate":"2022-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8996400/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45868567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sylvia Thurn, Katharina Kleinschmidt, Irena Kovačič, C. Wendl, R. Linker, S. Corbacioglu, F. Schlachetzki
{"title":"Transcranial Doppler sonography and the effect of haematopoietic stem cell transplantation in sickle cell disease","authors":"Sylvia Thurn, Katharina Kleinschmidt, Irena Kovačič, C. Wendl, R. Linker, S. Corbacioglu, F. Schlachetzki","doi":"10.1186/s42466-022-00175-y","DOIUrl":"https://doi.org/10.1186/s42466-022-00175-y","url":null,"abstract":"","PeriodicalId":94156,"journal":{"name":"Neurological research and practice","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44154626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Polyradiculitis and encephalomyelitis in the same patient following a SARS-CoV-2 vaccination","authors":"J. Finsterer","doi":"10.1186/s42466-022-00177-w","DOIUrl":"https://doi.org/10.1186/s42466-022-00177-w","url":null,"abstract":"","PeriodicalId":94156,"journal":{"name":"Neurological research and practice","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44535495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diagnosing SARS-CoV-2 vaccination associated rhombencephalitis requires comprehensive work-up and exclusion of differentials","authors":"J. Finsterer, F. Scorza, C. Scorza, A. Fiorini","doi":"10.1186/s42466-022-00178-9","DOIUrl":"https://doi.org/10.1186/s42466-022-00178-9","url":null,"abstract":"","PeriodicalId":94156,"journal":{"name":"Neurological research and practice","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45024923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Pedrosa, F. Gandor, W. Jost, C. Arlt, Koray Onuk, L. Timmermann
{"title":"Characterization of advanced Parkinson’s disease in Germany: results of the non-interventional OBSERVE-PD study","authors":"D. Pedrosa, F. Gandor, W. Jost, C. Arlt, Koray Onuk, L. Timmermann","doi":"10.1186/s42466-022-00176-x","DOIUrl":"https://doi.org/10.1186/s42466-022-00176-x","url":null,"abstract":"","PeriodicalId":94156,"journal":{"name":"Neurological research and practice","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48235811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Strunk, R. Veltkamp, S. Meuth, R. Chapot, M. Kraemer
{"title":"Intra-arterial application of nimodipine in reversible cerebral vasoconstriction syndrome: a neuroradiological method to help differentiate from primary central nervous system vasculitis","authors":"D. Strunk, R. Veltkamp, S. Meuth, R. Chapot, M. Kraemer","doi":"10.1186/s42466-022-00173-0","DOIUrl":"https://doi.org/10.1186/s42466-022-00173-0","url":null,"abstract":"","PeriodicalId":94156,"journal":{"name":"Neurological research and practice","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48684057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}