Neurological research and practice

Localized network damage related to white matter hyperintensities is linked to worse outcome after severe stroke.

Pub Date : 2025-08-19 DOI: 10.1186/s42466-025-00416-w Samuel C Olszówka, Benedikt M Frey, Jan F Feldheim, Lukas Frontzkowski, Paweł P Wróbel, Winifried Backhaus, Focko L Higgen, Hanna Braaß, Silke Wolf, Chi-Un Choe, Marlene Bönstrup, Bastian Cheng, Götz Thomalla, Philipp J Koch, Fanny Quandt, Christian Gerloff, Robert Schulz

Identification of a presymptomatic and early disease signature for amyotrophic lateral sclerosis (ALS): protocol of the premodiALS study.

Pub Date : 2025-08-19 DOI: 10.1186/s42466-025-00417-9 Laura Tzeplaeff, Ana Galhoz, Clara Meijs, Lucas Caldi Gomes, Andrej Kovac, Amrei Menzel, Hatice Değirmenci, Abir Alaamel, Hüseyin Can Kaya, Ali Günalp Çelik, Sine Dinçer, Meltem Korucuk, Sibel Berker Karaüzüm, Elif Bayraktar, Vildan Çiftçi, Uğur Bilge, Filiz Koç, Antonia F Demleitner, Anne Buchberger, Ricarda von Heynitz, Vincent Gmeiner, Christina Knellwolf, Mohammed Mouzouri, Joanne Wuu, A Nazli Başak, Peter Munch Andersen, Florian Kohlmayer, Nicholas J Ashton, Wojciech Kuban, Christof Lenz, Mary-Louise Rogers, Norbert Zilka, Philippe Corcia, Yossef Lerner, Markus Weber, Monika Turcanova Koprusakova, Hilmi Uysal, Michael Benatar, Michael P Menden, Paul Lingor

Stroke survivors show an overestimation of their on-road driving performance.

Pub Date : 2025-07-31 DOI: 10.1186/s42466-025-00406-y Daniel A Schlueter, Gernot Horstmann, Kim L Austerschmidt, Jessica Koenig, Maximilian Flieger, Thomas Beblo, Martin Driessen, Wolf Schäbitz, Max Toepper