Diana Crisan, Alexandru Badea, Sorina Danescu, Karin Scharffetter-Kochanek, Radu Badea, Christoph F Dietrich, Maria Crisan
{"title":"Comments on EFSUMB recommendations, the role of ultrasound in benign skin lesions.","authors":"Diana Crisan, Alexandru Badea, Sorina Danescu, Karin Scharffetter-Kochanek, Radu Badea, Christoph F Dietrich, Maria Crisan","doi":"10.11152/mu-4508","DOIUrl":"https://doi.org/10.11152/mu-4508","url":null,"abstract":"<p><p>The European Federation of Societies for Ultrasound in Medicine and Biology (EFSUMB) has been publishing guidelines, position papers and also technical reviews. In addition, comments have been published for illustration of such papers including recently the role of ultrasound in cutaneous neoplasms but also in the hepatobiliary system, pancreas, lung and other organs. In the current paper, we aim to summarize the typical sonographic findings of the most commonly benign cutaneous lesions.</p>","PeriodicalId":94138,"journal":{"name":"Medical ultrasonography","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144059197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Influence of an ultrasound-guided catheter-over-needle technique on the incidence of intravascular injection during caudal epidural injections: a prospective, randomized clinical trial.","authors":"Byeongcheol Lee, Daeseok Oh","doi":"10.11152/mu-4507","DOIUrl":"https://doi.org/10.11152/mu-4507","url":null,"abstract":"<p><strong>Aim: </strong>Caudal epidural injection is used for lumbosacral radicular pain but there is a risk of vascular injection. An ultrasound-guided catheter-over-needle technique was proposed to reduce this risk. This study compared the incidence of vascular injections between the catheter-over-needle and Tuohy needle methods for caudal epidural injections.</p><p><strong>Material and methods: </strong> This prospective, randomized clinical trial included patients aged ≥19 years with degenerative lumbar disease accompanied by radicular pain who were unresponsive to non-invasive treatments and scheduled for caudal epidural injection. The participants were randomized into two groups: catheter-over-needle and Tuohy needle groups. Under ultrasound guidance, the contrast medium was injected and observed in real time using fluoroscopy. An independent physician assessed the vascular injection rates.</p><p><strong>Results: </strong>The incidence of vascular injection was significantly lower in the catheter-over-needle group (15.7%) than in the Tuohy needle group (37.5%; p=0.014). Chronic pain lasting >12 months was a significant risk factor for vascular injection (p=0.035). However, no statistically significant association was found between sacral opening depth and vascular injection, although the sacral opening depth was shorter in patients who received intravascular injections.</p><p><strong>Conclusions: </strong>The catheter-over-needle technique significantly reduces the risk of vascular injection. The depth of the sacral opening may also influence vascular injection.</p>","PeriodicalId":94138,"journal":{"name":"Medical ultrasonography","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144061253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xuefeng Li, Ziman Chen, Ting Xie, Jieyi Liang, Fei Chen
{"title":"Enhancing sonologist examination performance with large language models: an analytical study of ChatGPT-4 and Claude 3.","authors":"Xuefeng Li, Ziman Chen, Ting Xie, Jieyi Liang, Fei Chen","doi":"10.11152/mu-4505","DOIUrl":"https://doi.org/10.11152/mu-4505","url":null,"abstract":"<p><strong>Aim: </strong>To evaluate the effectiveness of two large language models, ChatGPT-4 and Claude 3, in improving the accuracy of question responses by senior sonologist and junior sonologist.</p><p><strong>Material and methods: </strong>A senior and a junior sonologist were given a practice exam. After answering the questions, they reviewed the responses and explanations provided by ChatGPT-4 and Claude 3. The accuracy and scores before and after incorporating the models' input were analyzed to compare their effectiveness.</p><p><strong>Results: </strong>No statistically significant differences were found between the two models' responses scores for each section (all p>0.05). For junior sonologist, both ChatGPT-4 (p=0.039) and Claude 3 (p=0.039) significantly improved scores in basic knowledge. The responses provided by ChatGPT-4 also significantly improved scores in relevant professional knowledge (p=0.038), though their explanations did not (p=0.077). For all exam sections, both models' responses and explanations significantly improved scores (all p<0.05). For senior sonologist, both ChatGPT-4's responses (p=0.022) and explanations (p=0.034) improved scores in basic knowledge, as did Claude 3's explanations (p=0.003). Across all sections, Claude 3's explanations significantly improved scores (p=0.041).</p><p><strong>Conclusion: </strong>ChatGPT-4 and Claude 3 significantly improved sonologist' examination performance, particularly in basic knowledge.</p>","PeriodicalId":94138,"journal":{"name":"Medical ultrasonography","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144055999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alexis Delpierre, Baptiste Ait Slimane, Laurent Estrade, Juliette Manget, Samuel Callé, Franck Levassort, Frédéric Denis, Gaël Y Rochefort, Matthieu Renaud
{"title":"Sulcus measurement by high frequency ultrasound imaging ex-vivo: an exploratory study.","authors":"Alexis Delpierre, Baptiste Ait Slimane, Laurent Estrade, Juliette Manget, Samuel Callé, Franck Levassort, Frédéric Denis, Gaël Y Rochefort, Matthieu Renaud","doi":"10.11152/mu-4506","DOIUrl":"https://doi.org/10.11152/mu-4506","url":null,"abstract":"<p><strong>Aim: </strong>The aim of this study was to compare the measurement of periodontal pocket by ultrasound in comparison with gold standard measurements ex-vivo.</p><p><strong>Material and methods: </strong>A total of 12 hemi-jaws were included in the study. Ultrasound measurements of the sulcus were performed and then, sulcus depth was measured by manual probing. The reading of the ultrasound images was carried using ImageJ software. Reference points are made allowing the measurement of this sulcular space. To assess the hypothesis of normality of the data, a Kolmogorov-Smirnov test was performed for each of the samples due to the size of their population (>50). To complete this test, Lin's concordance test was also applied.</p><p><strong>Results: </strong>A total of 348 manual probing and 348 ultrasound imagines measurements were performed. The Lin concordance and correlation coefficients and their 95% confidence intervals obtained were 0.855 (95% CI [0.822; 0.855]). These data allow us to demonstrate the equivalence between the measurement of the depth of the periodontal pocket by ultrasound imaging and the measurement by manual probing.</p><p><strong>Conclusion: </strong>This study shows that the use of an ultrasound probe for periodontal imaging was comparable to the current gold standard for measuring the sulcus area. These promising results must be confirmed by measurements in humans.</p>","PeriodicalId":94138,"journal":{"name":"Medical ultrasonography","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144059473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A machine learning model based on high-frequency ultrasound for differentiating benign and malignant skin tumors.","authors":"Yishuo Qin, Zhirou Zhang, Xiaomeng Qu, Weijie Liu, Yumei Yan, Yanli Huang","doi":"10.11152/mu-4504","DOIUrl":"https://doi.org/10.11152/mu-4504","url":null,"abstract":"<p><strong>Aim: </strong>This study aims to explore the potential of machine learning as a non-invasive automated tool for skin tumor differentiation.</p><p><strong>Material and methods: </strong>Data were included from 156 lesions, collected retrospectively from September 2021 to February 2024. Univariate and multivariate analyses of traditional clinical features were performed to establish a logistic regression model. Ultrasound-based radiomics features are extracted from grayscale images after delineating regions of interest (ROIs). Independent samples t-tests, Mann-Whitney U tests, and Least Absolute Shrinkage and Selection Operator (LASSO) regression were employed to select ultrasound-based radiomics features. Subsequently, five machine learning methods were used to construct radiomics models based on the selected features. Model performance was evaluated using receiver operating characteristic (ROC) curves and the Delong test.</p><p><strong>Results: </strong>Age, poorly defined margins, and irregular shape were identified as independent risk factors for malignant skin tumors. The multilayer perception (MLP) model achieved the best performance, with area under the curve (AUC) values of 0.963 and 0.912, respectively. The results of DeLong's test revealed a statistically significant discrepancy in efficacy between the MLP and clinical models (Z=2.611, p=0.009).</p><p><strong>Conclusion: </strong>Machine learning based skin tumor models may serve as a potential non-invasive method to improve diagnostic efficiency.</p>","PeriodicalId":94138,"journal":{"name":"Medical ultrasonography","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144002249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christoph F Dietrich, Frauke Petersen, Michael Höpfner, Dieter Nürnberg, Deike Strobel, Johanna Vogelpohl, Christian Jenssen
{"title":"Ultrasound for detection of complications and evaluation of treatment response in inflammatory bowel disease (IBD)?","authors":"Christoph F Dietrich, Frauke Petersen, Michael Höpfner, Dieter Nürnberg, Deike Strobel, Johanna Vogelpohl, Christian Jenssen","doi":"10.11152/mu-4493","DOIUrl":"https://doi.org/10.11152/mu-4493","url":null,"abstract":"<p><p>Ultrasound (US) can be performed at the point of care by the treating physician, is safe, well tolerated and, therefore, can be repeated as often as clinically required and shortens the time to decision. An invaluable advantage of US is that the imaging is real-time and pathophysiological phenomena can be visualized dynamically. In addition, the multiparametric capabilities of US facilitate the evaluation of intestinal, peri-intestinal and some of the extra-intestinal manifestations of inflammatory boweldiseases (IBD).In the current series of papers a synopsis of recommendations for ultrasound in IBD guidelines, ultrasound parameters in inflammatory bowel disease including activities scores, the value of contrast enhanced ultrasound (CEUS), small intestinal contrast ultrasound (SICUS) and elastography, perineal ultrasound (PNUS), endoscopic ultrasound (EUS) including endorectal ultrasound (ERUS) and interventional ultrasound (INVUS) have been discussed and illustrated. This review discusses advantages, accuracy and limitations of ultrasound techniques for the diagnosis of intestinal, periintestinal and extra-intestinal complications of MC and CU and for monitoring treatment response.</p>","PeriodicalId":94138,"journal":{"name":"Medical ultrasonography","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144047550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Multimodal ultrasonography features of the extramedullary plasmacytomas in multiple myeloma: a retrospective case series study.","authors":"Jingyi Chen, Siqi Wei, Weixin Zhang, Zhengxu Sun, Xiaoyan Qu, Jing Hang","doi":"10.11152/mu-4503","DOIUrl":"https://doi.org/10.11152/mu-4503","url":null,"abstract":"<p><strong>Aims: </strong>To investigate the multimodal ultrasonography (US) features of extramedullary plasmacytomas (EMPs) in patients with multiple myeloma (MM).</p><p><strong>Material and methods: </strong>Nine patients with MM who were diagnosed EMPs and underwent multimodal ultrasonography were enrolled in this study. Clinical information and multimodal US results were retrospectively analyzed. The multimodal US with a standardized sonographic protocol including US, color Doppler flow imaging (CDFI), microvascular US, ultrasound elastography (UE) and contrast-enhanced ultrasound (CEUS) was performed on the enrolled patients.</p><p><strong>Results: </strong>This study included both males (4 of 9) and females (5 of 9), with ages ranging from 48 to 72 years. The nine lesions were located in the skin/muscle (7 of 9) and pleura (2 of 9). On US images, all lesions showed inhomogeneous solid hypoechogenicity without calcification. Vascularity was abundant (hypervascularization). CEUS images confirmed this vascular pattern (9 of 9) and presented hyperenhancement with enlarged range. On elastographic images, the lesions presented with high elastic score (3-4).</p><p><strong>Conclusions: </strong>An inhomogeneous hypoechoic soft tissue or visceral mass occurring in MM with increased vascularity, low elasticity, and hyperenhancement along with enlarged range can indicate the diagnosis of EMP on multimodal US images.</p>","PeriodicalId":94138,"journal":{"name":"Medical ultrasonography","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144061480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Echocardiography myocardial work assessment of chemotherapy-induced cardiotoxicity: a systematic review and meta-analysis.","authors":"Guyue Liu, Zhiyue Liu, Mingjian Lang","doi":"10.11152/mu-4502","DOIUrl":"https://doi.org/10.11152/mu-4502","url":null,"abstract":"<p><strong>Aim: </strong>The objective was to assess chemotherapy-induced cardiotoxicity by comparing changes in myocardial work indices (MWI) using echocardiographic myocardial work (MW).</p><p><strong>Material and method: </strong>A comprehensive search was performed in PubMed, Embase, and the Cochrane Library, covering literature up to June 2024.</p><p><strong>Results: </strong>A total of 13 non-randomized experimental studies (n=1,373) assessed changes in MWI of cancer patients treated with anthracyclines, trastuzumab/pertuzumab, or immune checkpoint inhibitors. After chemotherapy, adecrease was observed in the left ventricular ejection fraction (LVEF) (Pooled standard mean difference [SMD] = -0.75, 95% CI: -1.18, -0.31, p=0.001, I 2= 95.9%), global longitudinal strain (GLS) (Pooled SMD = -2.38, 95% CI: -3.10, -1.66, p<0.001, I 2= 97.9%), global work index (Pooled SMD = -1.27, 95% CI: -1.68, -0.86, p<0.001, I2= 95.0%), global constructive work (GCW) (Pooled SMD = -1.55, 95% CI: -2.10, -0.99, p<0.001, I 2= 96.9%), and global work efficiency (Pooled SMD = -1.66, 95% CI: -2.39, -0.94, p<0.001, I2= 98.2%). Conversely, global wasted work (GWW) increased (Pooled SMD = 1.17, 95% CI: 0.44, 1.89, p=0.002, I 2= 98.2%). Post-chemotherapy, GCW and GLS were below normal ranges, GWW exceeded normal values, and LVEF remained within normal limits across all subgroups.</p><p><strong>Conclusions: </strong>Echocardiographic MWI provides a non-invasive method for assessing cardiotoxicity induced by anthracyclines, trastuzumab / pertuzumab, or immune checkpoint inhibitors.</p>","PeriodicalId":94138,"journal":{"name":"Medical ultrasonography","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143733692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christian Jenssen, Frauke Petersen, Michael Höpfner, Dieter Nürnberg, Deike Strobel, Johanna Vogelpohl, Christoph F Dietrich
{"title":"Why and when are activity scores and advanced ultrasound techniques needed in inflammatory bowel disease (IBD)?","authors":"Christian Jenssen, Frauke Petersen, Michael Höpfner, Dieter Nürnberg, Deike Strobel, Johanna Vogelpohl, Christoph F Dietrich","doi":"10.11152/mu-4500","DOIUrl":"https://doi.org/10.11152/mu-4500","url":null,"abstract":"<p><p>In addition to avoidance of radiation exposure, the main advantages of ultrasound diagnostics in inflammatory bowel disease (IBD) patients are its' immediate availability, also as a component of the physical examination (extended point of care), its' repeatability and its' high patient comfort. The fact that the examination is carried out directly by the treating physician and is not delegated to the radiologist increases compliance and therapy adherence of the patients.In the current series of papers a synopsis of recommendations for ultrasound in IBD guidelines, ultrasound parameters in inflammatory bowel disease including activities scores, the value of contrast enhanced ultrasound (CEUS), small intestinal contrast ultrasound (SICUS) and elastography, perineal ultrasound (PNUS), endoscopic ultrasound (EUS) including endorectal ultrasound (ERUS), interventional ultrasound (INVUS), detection of disease complications (stenoses, fistula, abscess), extraintestinal manifestations, differential diagnosis, evaluation of treatment response and outlook are discussed and illustrated.</p>","PeriodicalId":94138,"journal":{"name":"Medical ultrasonography","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143733707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Deep learning-based automated detection and diagnosis of gouty arthritis in ultrasound images of the first metatarsophalangeal joint.","authors":"Lishan Xiao, Yizhe Zhao, Yuchen Li, Mengmeng Yan, Manhua Liu, Chunping Ning","doi":"10.11152/mu-4495","DOIUrl":"https://doi.org/10.11152/mu-4495","url":null,"abstract":"<p><strong>Aim: </strong>This study aimed to develop a deep learning (DL) model for automatic detection and diagnosis of gouty arthritis (GA) in the first metatarsophalangeal joint (MTPJ) using ultrasound (US) images.</p><p><strong>Materials and methods: </strong>A retrospective study included individuals who underwent first MTPJ ultrasonography between February and July 2023. A five-fold cross-validation method (training set = 4:1) was employed. A deep residual convolutional neural network (CNN) was trained, and Gradient-weighted Class Activation Mapping (Grad-CAM) was used for visualization. Different ResNet18 models with varying residual blocks (2, 3, 4, 6) were compared to select the optimal model for image classification. Diagnostic decisions were based on a threshold proportion of abnormal images, determined from the training set.</p><p><strong>Results: </strong>A total of 2401 US images from 260 patients (149 gout, 111 control) were analyzed. The model with 3 residual blocks performed best, achieving an AUC of 0.904 (95% CI: 0.887~0.927). Visualization results aligned with radiologist opinions in 2000 images. The diagnostic model attained an accuracy of 91.1% (95% CI: 90.4%~91.8%) on the testing set, with a diagnostic threshold of 0.328.</p><p><strong>Conclusion: </strong> The DL model demonstrated excellent performance in automatically detecting and diagnosing GA in the first MTPJ.</p>","PeriodicalId":94138,"journal":{"name":"Medical ultrasonography","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143733689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}