Tarek Mazzawi, Sara Haj Ali, Kim Nylund, Odd Helge Gilja
{"title":"Sigmoid wall thickness correlates with fecal calprotectin during irritable bowel syndrome exacerbation.","authors":"Tarek Mazzawi, Sara Haj Ali, Kim Nylund, Odd Helge Gilja","doi":"10.11152/mu-4592","DOIUrl":"10.11152/mu-4592","url":null,"abstract":"<p><strong>Aim: </strong>Patients with diarrhea-predominant irritable bowel syndrome (IBS-D) who present with symptom exacerbation [defined by a high IBS-Symptom Severity Scale (IBS-SSS)] may have increased fecal calprotectin (FC). Intestinal ultrasound (IUS) is used to measure bowel wall thickness (BWT). The aim of our study was to measure BWT in IBS-D patients, ulcerative colitis (UC) and healthy controls (HC), and compare BWT, IBS-SSS score, and FC level.</p><p><strong>Material and method: </strong>Patients with IBS-D and symptom exacerbation (n=100), active UC (n=25), and HC (n=30) were included. FC was measured in all groups. IBS-D patients with an IBS-SSS score >75 and FC level >50 µg/g underwent IUS and colonoscopy.</p><p><strong>Results: </strong>Patients with IBS-D had a (mean±SEM) IBS-SSS score of 268±11, FC level of 260±46 µg/g, and a normal colonoscopy. IUS showed a significant difference (p<0.0001) between sigmoid BWT for IBS-D (3.16±0.09 mm) and HC (1.6±0.12 mm). Color Doppler signals were also absent. A significant correlation between sigmoid BWT and FC level (r=0.48, p=0.0012) was found in patients with IBS-D.</p><p><strong>Conclusion: </strong>Compared to HC, sigmoid BWT was significantly increased in IBS-D patients with symptom exacerbation. Sigmoid BWT correlates significantly with FC levels during IBS-D symptom exacerbation.</p>","PeriodicalId":94138,"journal":{"name":"Medical ultrasonography","volume":" ","pages":"263-270"},"PeriodicalIF":2.3,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147481515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A neck mass suspected to be a branchial cleft cyst: a case of macrocystic lymphatic malformation.","authors":"Peihai Sun, Yihua Gao, Kuichang Yuan","doi":"10.11152/mu-4639","DOIUrl":"https://doi.org/10.11152/mu-4639","url":null,"abstract":"<p><p></p>","PeriodicalId":94138,"journal":{"name":"Medical ultrasonography","volume":"28 3","pages":"370-371"},"PeriodicalIF":2.3,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149042650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A strange mass on the face of the fetus: cutaneous hamartoma.","authors":"Bi Lei, Lang Liu, Hui Liu","doi":"10.11152/mu-4637","DOIUrl":"10.11152/mu-4637","url":null,"abstract":"<p><p></p>","PeriodicalId":94138,"journal":{"name":"Medical ultrasonography","volume":"28 3","pages":"367-368"},"PeriodicalIF":2.3,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149042680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical application of two-dimensional transvaginal ultrasound combined with contrast-enhanced ultrasound for the diagnosis and preoperative evaluation of cesarean scar pregnancy.","authors":"Jinfeng Yang, Ying Niu, Zhongya Xu","doi":"10.11152/mu-4647","DOIUrl":"https://doi.org/10.11152/mu-4647","url":null,"abstract":"<p><strong>Aim: </strong>To determine if contrast-enhanced ultrasound (CEUS) improves the diagnostic performance of conventional two-dimensional transvaginal ultrasound (2DTVUS) in cesarean scar pregnancy (CSP).</p><p><strong>Material and methods: </strong>This retrospective cohort study included patients with suspected CSP who were evaluated between January 2021 and June 2025. All the patients underwent both 2DTVUS and CEUS. 2DTVUS was used to assess myometrial thickness at the scar, gestational sac protrusion, and vascularity. CEUS was used to evaluate the enhancement pattern, time-to-peak, and peak intensity relative to the adjacent myometrium.</p><p><strong>Results: </strong>Histopathology confirmed 63 cases of CSP and 43 cases of non-CSP among the 106 patients who subsequently underwent pregnancy termination. 2DTVUS identified 95 cases as CSPs and 11 as non-CSPs, whereas CEUS identified 66 cases as CSPs and 40 as non-CSPs. Compared with 2DTVUS, CEUS showed higher specificity (97.6% vs. 63.4%, p<0.001), sensitivity (96.9% vs. 92.3%), accuracy (97.2% vs. 81.1%, p<0.001), positive predictive value (98.4% vs. 80.0%, p=0.0018), and negative predictive value (95.2% vs. 83.9%). ROC analysis demonstrated that CEUS had a higher AUC than 2DTVUS (0.972 vs. 0.779, p<0.001).</p><p><strong>Conclusion: </strong>CEUS complements 2DTVUS by sensitively depicting microvascular perfusion and quantifying the relationship between the gestational sac and the cesarean scar, thereby improving diagnostic accuracy and facilitating preoperative planning in patients with suspected CSP.</p>","PeriodicalId":94138,"journal":{"name":"Medical ultrasonography","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149043231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jan Nawratil, Kathleen Möller, Claudia Lucius, Ole Graumann, Christoph F Dietrich
{"title":"Quo vadis ultrasound: toward a terminologia sonographica.","authors":"Jan Nawratil, Kathleen Möller, Claudia Lucius, Ole Graumann, Christoph F Dietrich","doi":"10.11152/mu-4646","DOIUrl":"https://doi.org/10.11152/mu-4646","url":null,"abstract":"<p><p>The increasing use of artificial intelligence, automated image analysis, and robotic systems in ultrasound diagnostics necessitates a consistent, physically grounded, and cross-device comparable terminology. However, contemporary ultrasonographic findings are frequently described using historically evolved, metaphorical, and ambiguously defined terms. This semantic variability limits reproducibility, data harmonization, and the learning and reporting capacity of AI-based models. Ultrasound images do not represent direct anatomical depictions, but rather algorithmic reconstructions of acoustic interactions based on model-dependent assumptions. Artifacts and echo patterns, therefore, reflect the discrepancy between physical reality and mathematical approximation within signal processing. Inconsistent nomenclature widens the gap between measured variables, reconstruction models, and clinical interpretation. This paper analyses this structural problem and outlines a development framework for an internationally compatible Terminologia Sonographica. It proposes the systematic collection of existing descriptors, their translation into operationalizable categories, and consensus-based validation involving ultrasound societies. The aim is to establish an ontologically precise, interoperable semantic infrastructure for quality assurance, digital documentation, and future AI-supported decision-making.</p>","PeriodicalId":94138,"journal":{"name":"Medical ultrasonography","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149043234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Giulio Cocco, Vincenzo Ricci, Vito Cantisani, Andrea Delli Pizzi, Corrado Tagliati, Marco Di Serafino, Corrado Caiazzo, Gianfranco Vallone, Massimo Caulo, Antonio Corvino
{"title":"Dynamic ultrasound assessment of a post-surgical synovial hernia of the knee: a case report.","authors":"Giulio Cocco, Vincenzo Ricci, Vito Cantisani, Andrea Delli Pizzi, Corrado Tagliati, Marco Di Serafino, Corrado Caiazzo, Gianfranco Vallone, Massimo Caulo, Antonio Corvino","doi":"10.11152/mu-4648","DOIUrl":"https://doi.org/10.11152/mu-4648","url":null,"abstract":"<p><p>Small post-surgical synovial hernias of the knee joint may represent a diagnostic challenge, given the limited sensitivity of physical examination for detecting these rare complications. We report the case of a 25-year-old woman with persistent anterolateral knee pain and swelling two years after anterior cruciate ligament reconstruction was performed arthroscopically. Compression and release of the transducer over the pathological sonographic finding, combined with the Doppler box, revealed a bidirectional flow signal at the level of the defect (positive Cocco sign), consistent with a post-surgical synovial hernia. The Cocco sign enhanced direct visualization of fluid displacement through a narrow fascial defect, supporting its role as a dynamic adjunct during the sonographic examination.</p>","PeriodicalId":94138,"journal":{"name":"Medical ultrasonography","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149043185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sefa Tan, Banu Gokcen Tan, Ruhiye Resili, Sema Tuncer Uzun
{"title":"Feasibility and early clinical outcomes of ultrasound-guided coccygeal nerve pulsed radiofrequency in refractory post-traumatic coccygodynia.","authors":"Sefa Tan, Banu Gokcen Tan, Ruhiye Resili, Sema Tuncer Uzun","doi":"10.11152/mu-4649","DOIUrl":"https://doi.org/10.11152/mu-4649","url":null,"abstract":"<p><strong>Aims: </strong>To evaluate the feasibility, safety, early clinical outcomes of a staged ultrasound-guided coccygeal nerve intervention algorithm incorporating pulsed radiofrequency (PRF) in refractory post-traumatic coccydynia.</p><p><strong>Material and methods: </strong>Twelve patients underwent a two-phase routine clinical protocol: ultrasound-guided bilateral coccygeal nerve block followed, if pain persisted at three weeks, by PRF combined with a repeat nerve block. Outcomes included Numeric Rating Scale-sitting (NRS-sitting), sitting tolerance, and Patient Global Impression of Change (PGIC) over 8 weeks.</p><p><strong>Results: </strong>Feasibility endpoints were met with no complications. NRS-sitting decreased from 6.33±1.23 to 2.17±0.72 at week 8 (95% CI: 1.71-2.63; p<0.001). At week 8, 58.3% of patients could sit for >30 minutes, and 75% reported high satisfaction (PGIC scores of 6 or 7). Findings should be interpreted as preliminary feasibility and short-term clinical outcomes of the staged intervention algorithm.</p><p><strong>Conclusion: </strong>These preliminary findings suggest that a staged ultrasound-guided approach incorporating PRF is feasible and safe for refractory coccydynia, with short-term improvements in pain and functional sitting tolerance reflecting the overall staged protocol rather than the isolated effect of PRF. Larger randomized controlled trials with longer follow-up are required to determine clinical efficacy, long-term durability, and the incremental contribution of PRF.</p>","PeriodicalId":94138,"journal":{"name":"Medical ultrasonography","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149043200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kathleen Möller, Christian Görg, Andrius Cekuolis, Natalia Buda, Wolfgang Blank, Andrè Ignee, Christoph F Dietrich
{"title":"Ultrasound findings in rare pulmonary and pleural disorders: a case-based review.","authors":"Kathleen Möller, Christian Görg, Andrius Cekuolis, Natalia Buda, Wolfgang Blank, Andrè Ignee, Christoph F Dietrich","doi":"10.11152/mu-4634","DOIUrl":"https://doi.org/10.11152/mu-4634","url":null,"abstract":"<p><p>Transthoracic ultrasound (TUS) is an established imaging modality for the diagnosis and bedside monitoring of pleural effusions, pneumothorax, inflammatory pleural disease, thoracic wall lesions, peripheral pulmonary consolidations, and interstitial lung diseases. Contrast-enhanced ultrasound (CEUS) further improves lesion characterization by differentiating viable inflammatory tissue from necrosis and abscess formation. While the sonographic appearance of common thoracic diseases is well described, ultrasound findings in rare pulmonary and pleural conditions remain insufficiently documented. This review presents the characteristic transthoracic ultrasound (TUS) findings in several uncommon thoracic disorders, including abscessing fire-eater's pneumonia after paraffin aspiration, tracheal hemangioma, thoracic wall hemangioma, biliopleural fistula following percutaneous transhepatic cholangiodrainage (PTCD), bronchial rupture with hemopneumothorax, spontaneous pneumomediastinum, esophagopleural fistula, diaphragmatic cyst, and post-traumatic diaphragmatic paralysis. The sonographic findings are correlated with the clinical presentation and complementary imaging modalities.</p>","PeriodicalId":94138,"journal":{"name":"Medical ultrasonography","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148714983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Predicting early recurrence after microwave ablation in hepatocellular carcinoma: a clinicopathological-radiomics model based on ultrasound and identification of minimum ablation margin for high-risk tumors.","authors":"Ting Liu, Chuang Wu, Tiantian Dong, Yingying Jia, Ying Duan, Yongxin Li, Fang Nie","doi":"10.11152/mu-4632","DOIUrl":"https://doi.org/10.11152/mu-4632","url":null,"abstract":"<p><strong>Aim: </strong>To develop a comprehensive clinicopathologic-radiomic model for predicting early recurrence (ER) after thermal ablation for hepatocellular carcinoma (HCC), and to explore optimal ablation strategies for high-risk tumors.</p><p><strong>Material and methods: </strong>This multicenter retrospective study of 325 HCC patients undergoing microwave ablation divided them into training (n=182), internal (n=78), and external test sets (n=65). We extracted 3,499 radiomic features from pre-procedural ultrasound images and combined them with clinicopathological variables to train seven machine learning classifiers using 10-fold cross-validation. Model performance was assessed primarily by the area under the ROC curve, with decision curve and calibration analyses for clinical utility. The optimal minimal ablative margin (MAM) threshold for high-risk tumors was determined in the internal set using ROC analysis and validated externally.</p><p><strong>Results: </strong>The integrated clinicopathological-radiomics model demonstrated superior predictive performance, with an AUC of 0.870 (95% CI: 0.762-0.978) and showed good calibration and positive net benefit on decision curve analysis. SHapley Additive exPlanations analysis identified key predictive features, predominantly from arterial-phase CEUS images. In this cohort, a larger MAM (threshold 7.7 mm derived internally) was associated with lower ER in predicted high-risk tumors.</p><p><strong>Conclusion: </strong>An integrated clinicopathological-radiomics model effectively predicts ER of HCC following microwave ablation and provides an effective strategy for high-risk tumors to reduce ER occurrence.</p>","PeriodicalId":94138,"journal":{"name":"Medical ultrasonography","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148714860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Application of high frame rate contrast-enhanced ultrasound in carotid plaque neovascularization: a preliminary inter-physician comparison study.","authors":"Shibo Qiu, Jingjing Shi, Shan Tang, Ruyu Zheng, Ziyue Hu, Xiang Jing, Yanmin Kan","doi":"10.11152/mu-4633","DOIUrl":"https://doi.org/10.11152/mu-4633","url":null,"abstract":"<p><strong>Aims: </strong> To preliminarily evaluate the clinical value of high frame rate contrast-enhanced ultrasound (H-CEUS) for assessing intraplaque neovascularization (IPN) in carotid arteries among physicians with different levels of experience.</p><p><strong>Methods: </strong> A total of 66 patients with 114 carotid plaques who underwent both CEUS and H-CEUS were enrolled. One senior physician and two beginners (A and B) performed semi-quantitative grading of the number and distribution of IPN. The inter-modality agreement between CEUS and H-CEUS was assessed. The consistency between the senior physician and the beginners was compared. Learning curves were used to analyze the beginners' proficiency progression in evaluating IPN using CEUS and H-CEUS.</p><p><strong>Results: </strong> Assessment of IPN using the two contrast-enhanced ultrasound modes showed moderate interobserver agreement among senior physicians. With H-CEUS mode, the senior physician and two beginners demonstrated strong interobserver agreement in assessing both the number (p<0.001) and distribution (p<0.001) of IPN. The learning curve analysis further revealed that, H‑CEUS enabled beginners A and B to achieve competency faster and attain higher final concordance rates than CEUS.</p><p><strong>Conclusion: </strong>This technique provides clear visualization of intraplaque neovascularization, thereby offering a more objective basis for accurate assessment and demonstrating potential clinical value.</p>","PeriodicalId":94138,"journal":{"name":"Medical ultrasonography","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148714793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}