Medical archives (Sarajevo, Bosnia and Herzegovina)最新文献

{"title":"The Mesentery's Pivotal Role in the Brain-Gut-Liver Axis.","authors":"Muharem Zildzic, Nizama Salihefendic, Izet Masic","doi":"10.5455/medarh.2024.78.4-8","DOIUrl":"10.5455/medarh.2024.78.4-8","url":null,"abstract":"<p><strong>Background: </strong>Prior to 2012, the mesentery was perceived as a fragmented structure, lacking distinct functional and anatomical characteristics, and was merely considered part of other digestive organs. Dr. J. Calvin Coffey's in 2012 in his study redefined the mesentery as a distinct organ with a clearly defined anatomical and histological structure, although its specific function remains under investigation. The continuous structure and unique tissue properties of the mesentery classify it as the 78th independent organ in the human body. Insights into mesenteric adipose tissue have enhanced our understanding of normal metabolic processes and disease etiology, impacting health significantly. Experimental and clinical research highlights the vital roles of visceral adipose tissue, influencing neighboring organ function. The interaction within the brain-gut-liver axis is illuminated by the newfound functions of mesenteric adipose tissue, emphasizing its independent organ status.</p><p><strong>Objective: </strong>This study aims to evaluate the latest findings on the structure and function of the mesentery, focusing on visceral-mesenteric adipose tissue, and assess its role as a new organ in the brain-gut-liver axis.</p><p><strong>Methods: </strong>A comprehensive analysis of clinical and experimental studies on the mesentery's structure and function was conducted, focusing on recent discoveries regarding mesenteric adipose tissue and its role in the brain-gut-liver axis.</p><p><strong>Results and discussion: </strong>Recent research has revealed the mesentery's unique functions, particularly in mesenteric adipose tissue. Mesenteric adipose tissue plays a crucial role in metabolic functions and influences disease onset. It acts as a vital link in the brain-gut-liver axis, directly influencing hepatic metabolism and disorders such as metabolic syndrome.</p><p><strong>Conclusion: </strong>Scientific evidence confirms the mesentery's anatomical and functional specificities, solidifying its status as the 78th independent organ in the human body. It serves as a crucial link in the brain-mesentery-small intestine-liver axis, impacting health and disease. Ongoing research holds promise for advancing our understanding of pathophysiological mechanisms and treatment approaches for metabolic syndrome and other chronic diseases.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"78 1","pages":"4-8"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10928676/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140121708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantitative Assessment of CT Pulmonary Angiogram (CTPA) in SCD Patients in Comparison to non-SCD Cases in Saudi Arabia.","authors":"Dunya Alfaraj, Hussain Alkhawaja, Mohannad Alghamdi, Zahraa Almuhanna, Iba Alfawaz, Abdulbary Alhalimi, Ali Aljazzar, Abdullah Bunaian, Hassan Almadan, Arwaa Haji, Abdullah Alamoudi, Fatimah Alfaraj, Yara Almazyad","doi":"10.5455/medarh.2024.78.207-210","DOIUrl":"10.5455/medarh.2024.78.207-210","url":null,"abstract":"<p><strong>Background: </strong>Sickle cell disease (SCD) is a genetic disorder caused by a mutation in the β-globin gene, leading to systemic complications, including stroke, avascular necrosis, and acute chest syndrome. The disease is most prevalent in regions such as sub-Saharan Africa, the Mediterranean, and the Middle East, with Saudi Arabia showing significant variability in prevalence and severity across its provinces.</p><p><strong>Objectives: </strong>This study focuses on comparing the quality of CT pulmonary angiography (CTPA) and the rates of pulmonary embolism (PE) diagnosis between SCD and non-SCD patients, addressing discrepancies in detection sensitivity and clinical outcomes.</p><p><strong>Methods: </strong>We conducted a retrospective comparison between 60 adult SCD patients and 60 age-matched controls, all of whom were evaluated for suspected PE in our emergency department using an MDCT scanner. Data, including demographic and clinical information, as well as CT findings, were extracted from electronic health records.</p><p><strong>Results: </strong>In SCD patients, the rate of positive CT pulmonary angiograms was 13.3% (8/60), while in non-SCD matched controls, it was 18.3% (11/60). There was no significant difference in the rate of positive CTPA studies (p=0.453). SCD patients exhibited significantly lower enhancement in the main pulmonary artery (PA) (mean 249.9 HU) compared to control subjects (mean 283.7 HU) (p-value= 0.043). Moreover, hemoglobin levels were notably lower in SCD patients (p-value < 0.001).</p><p><strong>Conclusion: </strong>SCD patients demonstrated no significant difference in the rate of positive studies for acute PE when compared with controls undergoing CTPA. Furthermore, the lower main PA enhancement in SCD patients supports the hypothesis suggesting reduced sensitivity of CT angiography in detecting PE in this population. Quality improvement initiatives should concentrate on individualized protocol optimization to enhance enhancement quality and increase the likelihood of a definitive diagnosis.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"78 3","pages":"207-210"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11813207/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143412110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of UVA vs UVB Photoaging Rat Models in Short-term Exposure.","authors":"Elly Mayangsari, Arifa Mustika, Nurdiana Nurdiana, Nozlena Abdul Samad","doi":"10.5455/medarh.2024.78.88-91","DOIUrl":"https://doi.org/10.5455/medarh.2024.78.88-91","url":null,"abstract":"<p><strong>Background: </strong>Prolonged exposure to sunlight is known to induce photoaging of the skin, leading to various skin changes and disorders, such as dryness, wrinkles, irregular pigmentation, and even cancer. Ultraviolet A (UVA) and ultraviolet B (UVB) radiation are particularly responsible for causing photoaging.</p><p><strong>Objective: </strong>This study aims to identify and compare photoaging rat models exposed to UVA and UVB.</p><p><strong>Methods: </strong>This research method compared macroscopic (scoring degree of wrinkling) and microscopic (histology) signs and symptoms on skin samples of rat exposed to UVA and UVB for 4 weeks at a radiation dose of 840mJ/cm2.</p><p><strong>Results: </strong>The results of this study indicated that the degree of wrinkling was highest in rat skin exposed to UVB rays by 51% (p<0.05). UVB histological results showed that the epidermis layer (40 µm, p<0.05) was thickened and the dermis layer (283 µm, p<0.05) was thinned in the skin of mice exposed to UVB light. The UVB group, showed the density of collagen in the dermis with a mean value of 55% (p<0.05).</p><p><strong>Conclusion: </strong>Our results suggest that short-term exposure to UVB radiation (in the acute, subacute or subchronic phase) induces more rapid and pronounced damage to rat skin when compared to UVA radiation exposure.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"78 2","pages":"88-91"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10983087/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140870519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Angio-Jet Thrombolysis for Traumatic Inferior Vena Cava Thrombosis; Case Report and Review of Literature.","authors":"Humood Alsadery, Omar Abdulqader Bamalan, Kawther Abduljabbar Boumarah, Ali Alsaffar, Bander Aldhafery, Mohammed S Foula, Mamoun Nabri, Adel G Elbagir","doi":"10.5455/medarh.2024.78.164-169","DOIUrl":"https://doi.org/10.5455/medarh.2024.78.164-169","url":null,"abstract":"<p><strong>Background: </strong>Inferior vena cava thrombosis (IVC-Th) is a rare clinical entity after blunt abdominal trauma. It has both diagnostic and therapeutic dilemmas. Pulmonary embolism is the most dreadful complication and the leading cause of mortality after IVC-Th. Therefore, accurate prompt diagnosis is crucial.</p><p><strong>Objective: </strong>The aim of this article was to present a case of IVC-Th in a young male patient who had a blunt traumatic abdominal injury after a motor vehicle accident.</p><p><strong>Case presentation: </strong>The patient was brought to emergency department and was successfully managed by angio-jet thrombolysis. He developed a transient contrast nephropathy that was recovered after continuous renal replacement therapy. Several management options have been proposed in the literature, including conservative, endovascular and operative management.</p><p><strong>Conclusion: </strong>Angio-jet is a recent promising technique for managing of venous thrombosis. However, its use in cases of IVC-Th is not extensively discussed in the literature.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"78 2","pages":"164-169"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10983088/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140873071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship Between Quality of Sleep and Psychological Well-being Among Frontline Nurses During the COVID-19 Pandemic in Saudi Arabia.","authors":"Eman Abdulla Alabdullatif, Rana Ali Alameri, Reem Nasser Mohammed Al-Dossary","doi":"10.5455/medarh.2024.78.22-28","DOIUrl":"10.5455/medarh.2024.78.22-28","url":null,"abstract":"<p><strong>Background: </strong>The coronavirus 2019 (COVID-19) pandemic is a world health emergency crisis that challenges the global health system and healthcare providers, especially frontline nurses' physical and mental well-being.</p><p><strong>Objective: </strong>The aim of the study was to examine the association between depression, anxiety, and sleep quality among nurses working in Saudi Arabian hospitals during the COVID-19 pandemic.</p><p><strong>Methods: </strong>This is an quantitative cross-sectional study. An online self-reported data was collected from 187 nurses who were on duty during COVID-19 pandemic.</p><p><strong>Results: </strong>About 87.2% of the nurses were female nurses; not surprising that 88% had poor sleep quality; 44.4% had moderate anxiety, and 44% of the studied nurses had mild to moderate depression. The study revealed that there was an association between level of anxiety and poor sleep quality. Poor sleep quality and emotional stability of nurses play a major role in quality of care and patients' safety.</p><p><strong>Conclusion: </strong>We conclude that healthcare leaders should adopt an occupational wellbeing program for nurses that focuses on their psychological wellbeing and sleep quality.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"78 1","pages":"22-28"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10928683/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140121705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pathohistological Diagnosis of Burkitt's Lymphoma After Cervical Biopsy-Case Report with Literature Review.","authors":"Amela Ceric, Amela Banicevic, Zvjezdana Ritan Micic, Danijela Dubravac, Bozana Babic","doi":"10.5455/medarh.2024.78.250-253","DOIUrl":"10.5455/medarh.2024.78.250-253","url":null,"abstract":"<p><strong>Background: </strong>Burkitt's lymphoma (BL)belongs to the group of lymphomas with an aggressive clinical course. It is a rare form of lymphoma in adults with an incidence of 1200 patients per year in the USA.</p><p><strong>Objective: </strong>The aim of this article was to present for the first time the case of a patient in whom Burkitt's lymphoma was proven by biopsy and curettage of the uterus, and at the same time in the biopsy of palatine tonsil and bone.</p><p><strong>Case report: </strong>A 64-year-old female patient who comes because of difficulty in swallowing, enlarged neck lymph nodes and vaginal bleeding. Under diagnosis Lymphoma non Hodgkin Burkitt CS IV B, ECOG 3, IPI 5 (high risk), R-IPI:5 (poor prognostic index) introduction of IHT R-CHOP 4 cycles with therapeutic response.</p><p><strong>Conclusion: </strong>A multidisciplinary approach is needed in the case of suspicion and diagnosis of BL, which is most often in an advanced form.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"78 3","pages":"250-253"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11854893/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143506686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Minimally Invasive Aortic Valve Replacement: Case Series Study.","authors":"Alen Karic, Harun Avdagic, Novica Kalinic, Ervin Busevac, Alma Krajnovic, Sekib Sokolovic","doi":"10.5455/medarh.2024.78.305-308","DOIUrl":"10.5455/medarh.2024.78.305-308","url":null,"abstract":"<p><strong>Background: </strong>Degenerative aortic stenosis is a prevalent and severe condition necessitating aortic valve replacement (AVR) when the valve area critically narrows to 0.7 cm² or when symptoms are manifested. Traditional AVR via median sternotomy, poses considerable risks for patients with comorbidities or advanced age.</p><p><strong>Objective: </strong>This study evaluates the efficacy and safety of mini sternotomy aortic valve replacement (MSAVR), a minimally invasive technique designed to reduce surgical trauma, improve postoperative recovery, and lower healthcare costs.</p><p><strong>Methods: </strong>A reversed L-type upper partial sternotomy (RLUPS) approach was performed in five patients focusing on standardized surgical procedures, and rigorous postoperative care. Key findings indicate that MSAVR markedly reduces postoperative complications, ICU stay, and overall hospital stay compared to traditional sternotomy.</p><p><strong>Results: </strong>The median postoperative length of stay was seven days for MSAVR versus 12 days for traditional sternotomy, with ICU stays of 52 hours and 119 hours, respectively. Our study also highlights the cost-effectiveness of MSAVR, with decreased hospital costs per patient due to reduced ICU resource utilization and shorter hospital stays. These findings suggest that MSAVR is a valuable and advantageous alternative to traditional sternotomy, offering substantial benefits in terms of patient outcomes and healthcare efficiency.</p><p><strong>Conclusion: </strong>Our work underscores the potential of minimally invasive techniques in improving the management of severe degenerative aortic stenosis, marking a significant advancement in the field of cardiac surgery.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"78 4","pages":"305-308"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11838833/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143470341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Orbital Manifestations of Hodgkin Lymphoma in a Pediatric Patient: a Case Report.","authors":"Ivana Gabric, Ana Pupic-Bakrac, Mateja Jagic, Alma Biscevic","doi":"10.5455/medarh.2024.78.322-325","DOIUrl":"10.5455/medarh.2024.78.322-325","url":null,"abstract":"<p><strong>Background: </strong>Hodgkin lymphoma (HL) is primarily characterized by the presence of Reed-Sternberg cells and predominantly affects the lymph nodes. However, it can also manifest in extranodal sites, including rare instances of orbital involvement.</p><p><strong>Objective: </strong>This report aims to present atypical symptoms associated with HL and its orbital manifestations in a pediatric patient.</p><p><strong>Case report: </strong>To discuss the clinical presentation, diagnostic journey, and management of a 4-year-old boy who exhibited orbital manifestations of HL. Initially, he was misdiagnosed as having an infectious process due to symptoms such as ptosis (drooping eyelids) and eyelid edema (swelling). Consequently, the patient received inappropriate treatments that delayed the correct diagnosis. This case highlights the challenges posed by atypical presentations in pediatric patients and underscores the importance of considering malignancy in the differential diagnosis. It also emphasizes the necessity of a multidisciplinary approach to achieve accurate and timely diagnosis and treatment.</p><p><strong>Conclusion: </strong>Through this case, we aim to enhance the understanding of orbital manifestations of HL and emphasize the need for increased awareness among clinicians when encountering unusual orbital findings in children.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"78 4","pages":"322-325"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11838828/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143470343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unbalanced Translocation in a Phenotypically Normal Male Patient Detected by Karyotyping and Array-comparative Genomic Hybridization.","authors":"Mai Trong Hung, Dinh Thuy Linh, Do Khac Huynh, Than Thi Thu Canh, Phan Thi Huyen Thuong, Do Tuan Dat","doi":"10.5455/medarh.2024.78.309-312","DOIUrl":"10.5455/medarh.2024.78.309-312","url":null,"abstract":"<p><strong>Background: </strong>nbalanced translocations can cause developmental delay, intellectual disability, growth problems, dysmorphic features, and congenital anomalies Unbalanced chromosome rearrangements that are cytogenetically visible account for ~3% of all recognized chromosome abnormalities. A lot of unbalanced translocations have been reported.</p><p><strong>Objective: </strong>Here, we present an individual who has an unbalanced translocation caused by deletion of the terminal region of chromosome 5p encompassing 170 kb coupled with a 11.4 Mb duplication of the terminal region of chromosome 18q..</p><p><strong>Case presentatioin: </strong>We report the first case of unbalanced translocation in a phenotypically normal male after performing clinical phenotyping, cytogenetic analyses and then array-comparative genomic hybridization after detection of unbalanced translocation in his fetus. Conventional G-banded karyotyping showed additional chromatin of unknown origin on the long arm of chromosome 5: 46,XX,add(5)(p15.3). The microarray result confirmed an unbalanced translocation with the loss of ~170kb of chromosome 5p and duplication of 11.4Mb of the long arm of chromosome 18 (arr[GRCh37]5p15.33(22149_192836)x1, 18q22.1q23(66590438_78012829)x3 of a normal adult.</p><p><strong>Conclusion: </strong>This is the first time we found the unbalanced translocation in a totally healthy man to our knowledge. Therefore, the karyotypes of the parents should be indicated whenever the unbalanced translocation detected in a fetus to have more data for prognosis.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"78 4","pages":"309-312"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11838831/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143470336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Experience of Using a Combination of Dexamethasone and Levofloxacin After Cataract Surgery.","authors":"Tomislav Kuzman, Ivana Gabric, Ana Meter, Ivan Skegro, Sanja Masnec, Miro Kalauz, Ana Pupic-Bakrac","doi":"10.5455/medarh.2024.78.127-130","DOIUrl":"https://doi.org/10.5455/medarh.2024.78.127-130","url":null,"abstract":"<p><strong>Background: </strong>Where routine prophylactic antibiotics have been adopted following cataract surgery, rates of endophthalmitis have been decreasing. Intracameral and topical antibiotics are currently used to prevent endophthalmitis after cataract surgery. When applying topical antibiotics, there are different recommendations on the frequency and duration of therapy. The development of bacterial resistance to the excessive and long-term use of antibiotics is a growing problem worldwide. The goal is to achieve a good antibiotic effect with the shortest possible use of antibiotics.</p><p><strong>Objective: </strong>The aim of this study was to compare the effectiveness of a new combination therapy of dexamethasone and levofloxacin for seven days after cataract surgery with the previous regimen of dexamethasone, neomycin sulfate, and polymyxin B, which was given for 21 days.</p><p><strong>Methods: </strong>A retrospective analysis of medical records and administered a questionnaire was conducted to assess the effectiveness of postoperative therapy in our cataract surgery patients. The study involved 52 patients who underwent surgery within the last year, performed by a single surgeon at our institution. The findings can help us improve the quality of care we provide and optimize our patients' overall quality of life.</p><p><strong>Results: </strong>We conducted an in-depth study on 52 individuals who underwent cataract surgery at our institution. The prescribed therapeutic regimen for the participants included administering Ducressa solution four times daily for the first seven days and Maxidex solution three times daily for the subsequent 14 days. The study found that none of the participants experienced complications after surgery, and all found it easy to instill the medication. The prescribed regimen effectively managed the postoperative recovery of the participants, and the medication was well-tolerated.</p><p><strong>Conclusion: </strong>Our research found that a new combination of levofloxacin and dexamethasone, when used topically, may require a shorter treatment period, reducing the risk of antibiotic resistance and providing a safe alternative for endophthalmitis prevention.</p>","PeriodicalId":94135,"journal":{"name":"Medical archives (Sarajevo, Bosnia and Herzegovina)","volume":"78 2","pages":"127-130"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10983092/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140854801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}