Materia socio-medica最新文献

{"title":"The Role of Modifying Risk Factors as Well as Body Mass Index, Waist Circumference and Hip to Waist Ratio as Anthropometric Indicators and Parameters of Obesity in the Occurence of Stroke.","authors":"Merita Tiric-Campara, Edina Djozic, Suljo Kunic, Amra Salkic, Amel Amidzic, Amira Skopljak","doi":"10.5455/msm.2024.36.137-142","DOIUrl":"10.5455/msm.2024.36.137-142","url":null,"abstract":"<p><strong>Background: </strong>Evaluated values of body mass index (BMI), waist circumeference (WC) and waist-to-hip ratio (WHR) increase the risk of stroke, but the extent to which this is mediated by hypertension, diabetes, lipid status, smoking and alcohol consumption is not fully understood.</p><p><strong>Objective: </strong>The aim of this research is to examine the influence of modifying and non-modifying factors as well as obesity defined through BMI, WC and WHR on the occurrence of stroke.</p><p><strong>Methods: </strong>A total of 440 subjects were included in the cohort divided in to two groups. The first group were patients with stroke and another without stroke. We investigate modifable factor for stroke (hypertension (HTA), lipid status, diabetes mellitus (DM), smoking, alcohol consumption, educational status) as well as WHR, BMI and WC as determinants for obesitiy.</p><p><strong>Results: </strong>The majority of respondents in both groups had a secondary level of education. Smoking and alcohol consumption were slightly more prevalent in the group without stroke, while HTA and DM were slightly more prevalent in the group with stroke, but without a statistically significant difference. The largest number of respodents without stroke had HDL cholesterol values in the range of optimal >1.5, 70.9%, while 35.5% of respodents with stroke had values in the risk range, as well as 32.3% in the high risk range. LDL cholesterol values were on average statistically significantly higher in the group of respodents with stroke - 3.77±1.29 compared to the values in respodents without stroke - 3.20±1.20. The largest WC had patients with a hemorrhagic stroke 96.4 ± 15.5 cm. The average BMI was slightly higher in the group of patients with embolic stroke (28.5 ± 2.8) compared to patients with hemorrhagic stroke (28.4 ± 5.9) and thrombotic stroke (28.1 ± 4, 2). WHR was almost identical in all three types of stroke.</p><p><strong>Conclusion: </strong>There is correlation between modifable risk factor and obesity in stroke occurence.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"36 2","pages":"137-142"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11663001/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142879331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigating the Interrelationships Between Obesity, Academic Achievement, Physical Activity, and Social Support Among Jazan University Students.","authors":"Omar Oraibi, Mohammed Somaili, Khaled Daghriri, Mohammed Alameer, Mohamed Arishi, Ali Sahli, Mohammed Haidar, Atiah Najmi, Faisal Otaif, Hanadi Abueishah, Bassem Oraibi, Abdulhameed Alhazmi, Luai Alhazmi","doi":"10.5455/msm.2024.36.59-64","DOIUrl":"https://doi.org/10.5455/msm.2024.36.59-64","url":null,"abstract":"<p><strong>Background: </strong>In developing and developed countries, the prevalence of overweight and obesity has grown. The college phase is a critical period during which healthy behaviors are learned through lifestyle and social environment. College students are prone to increased stress, negatively affecting their daily activities and academic performance.</p><p><strong>Objective: </strong>The general study objective was to investigate the prevalence of obesity among Jazan University students.</p><p><strong>Methods: </strong>This observational cross-sectional study used a pre-tested self-administered anonymous electronic questionnaire to evaluate the prevalence of obesity among 474 Jazan University students and its association with academic performance, physical activity, and social support. Data were analyzed using the Statistical Package for the Social Sciences, and associations between variables were assessed using the chi-square test.</p><p><strong>Results: </strong>Approximately 21% and 9.2% of the male and female students were obese, respectively, and the prevalence of obesity significantly differed between them. The use of one or more tobacco products was significantly associated with the prevalence of obesity (P < 0.001); the prevalence of obesity was substantially higher among the tobacco product users than among the non-users (35.3% vs. 14.4%). The presence of a morbidity was also significantly associated with the prevalence of obesity (P = 0.007); the prevalence of obesity was significantly higher among the students with at least one comorbidity than among the medically free students (28.8% vs. 14.9%). Conversely, obesity was not associated with academic performance and depression. Specifically, the grade point average was not affected across the academic years (P = 0.085 and P = 0.308, respectively).</p><p><strong>Conclusion: </strong>Obesity is significantly associated with male sex and the use of one or more tobacco products. This finding warrants the need for strategic and multidisciplinary plans at all levels to encourage healthy behaviors among college students, including an active, healthy lifestyle.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"36 1","pages":"59-64"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10999139/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140872587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of Non-surgical Treatment of Periodontal Diseases Using the Vector® Paro Pro Ultrasonic Device.","authors":"Mirjana Gojkov Vukelic, Sanja Hadzic, Enes Pasic, Indira Mujic Jahic, Arma Muharemovic, Anisa Zoronjic","doi":"10.5455/msm.2024.36.305-309","DOIUrl":"10.5455/msm.2024.36.305-309","url":null,"abstract":"<p><strong>Background: </strong>Non-surgical periodontal therapy, including mechanical debridement and root planning, is the gold standard in the treatment of periodontal diseases. The most commonly used instruments for non-surgical therapy are sonic/ultrasonic devices and manual instruments such as curettes.</p><p><strong>Objective: </strong>This study evaluates the clinical effectiveness and patient experience of non-surgical periodontal therapy using the Vector® Paro Pro ultrasonic device, emphasizing its impact on periodontal indices and patient comfort.</p><p><strong>Methods: </strong>Fifty patients with gingivitis, periodontitis, or peri-implantitis participated. Baseline data, including Plaque Index (PI), Gingival Index (GI), Papillary Bleeding Index (PBI), Probing Depth (PD), and Clinical Attachment Loss (CAL), were recorded. Patients underwent treatment using the Vector® Paro Pro system. Evaluations were conducted at baseline, two weeks, and one month post-therapy. Statistical analyses utilized repeated measures ANOVA and paired t-tests, with a significance threshold of p<0.05. Patient experience was assessed via a questionnaire.</p><p><strong>Results: </strong>All periodontal indices showed significant improvement post-therapy. The mean PI decreased from 1.18±0.12 to 0.52±0.08 after two weeks and 0.44±0.09 after one month (p<0.001). Significant reductions were observed in PBI (from 1.68±0.10 to 0.46±0.09) and PD (>4 mm pockets: from 5.55±0.19 to 3.65±0.45; p<0.001). CAL improved significantly (from 0.80±0.18 to 0.70±0.16 after one month; p<0.001). Patient-reported outcomes revealed that 98% experienced no pain during therapy.</p><p><strong>Conclusion: </strong>The Vector® Paro Pro ultrasonic device demonstrated significant clinical improvements in periodontal health, particularly in bleeding reduction and deep pocket management. Its hydroxyapatite-enhanced fluid effectively polished root surfaces and reduced post-therapeutic sensitivity. Patients reported minimal discomfort, underscoring the device's potential as a comfortable, efficient alternative for non-surgical periodontal therapy. Further studies with longer follow-up periods are recommended to confirm these findings.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"36 4","pages":"305-309"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11830227/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143443110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Skopje Declaration on Scientific and Publishing Integrity in Biomedicine.","authors":"Dijana Plasheska Karanfilska, Valentin Mircheski, Doncho Donev, Gordana Ristovska, Nevzat Elezi, Vladimir Trajkovski, Ilija Gligorov","doi":"10.5455/msm.2024.36.236-239","DOIUrl":"10.5455/msm.2024.36.236-239","url":null,"abstract":"","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"36 3","pages":"236-239"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11693119/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142924385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring Bevacizumab's Role in Gynecological Cancers: An Up-to-Date Narrative Review Focusing on Ovarian Cancer.","authors":"Elias Liolis, Francesk Mulita, Angelos Koutras, Thomas Makatsoris, Gregory Sivolapenko","doi":"10.5455/msm.2024.36.268-279","DOIUrl":"10.5455/msm.2024.36.268-279","url":null,"abstract":"<p><strong>Background: </strong>The Gynecological cancers, including ovarian cancer, endometrial cancer, breast cancer, and cervical cancer, have increased in frequency lately and it is estimated that one million cases are diagnosed every year worldwide. Bevacizumab is considered one of the first anti-angiogenic therapies as it is a monoclonal antibody binding to factors essential for tumor angiogenesis.</p><p><strong>Objective: </strong>This paper aims to review the most important findings of the literature that highlight the role of bevacizumab in gynecological cancers with a special emphasis on ovarian cance.</p><p><strong>Methods: </strong>For this narrative review, an extensive literature search was conducted using Pubmed and Web of Science to collect the most important papers investigating the role of bevacizumab in gynecological cancers, such as cervical cancer, breast cancer, endometrial cancer, and ovarian cancer.</p><p><strong>Results: </strong>Results regarding its use as monotherapy or in combination with chemotherapy and other regimens will be presented. A particular focus will be held also on findings regarding its safety and potential toxicity as well as its effectiveness.</p><p><strong>Conclusion: </strong>Bevacizumab is a key agent in the treatment of all gynecological cancers especially in the case of ovarian cancer as there is extensive evidence of its efficacy as monotherapy as well as in combination with other agents, with careful patient dosing. However, future research should focus also on the investigation of its use in other gynecological cancers. Furthermore, more investigation is required regarding its use in specific subtypes of cancer, associated e.g. with specific mutations or polymorphisms, or on factors that can affect its efficiency, such as the BMI as indicated by some studies. Finally, it should be noted that though this is not a systematic review of the literature, it highlights the more important findings paving the road for future research and guidelines about the appropriate use of bevacizumab in gynecological cancers.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"36 4","pages":"268-279"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11830232/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143443111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effectiveness of Some Chronic Pulmonary Management Units for Patients With COPD and Asthma in Vietnam.","authors":"Nguyen Thi Nguyet, Vu Dinh Tien, Nguyen Thi Huong Giang, Ngo Thi Huyen, Tran Thi Ly","doi":"10.5455/msm.2024.36.288-293","DOIUrl":"10.5455/msm.2024.36.288-293","url":null,"abstract":"<p><strong>Background: </strong>Asthma and chronic obstructive pulmonary diseases are chronic diseases and have high mortality rates in Vietnam and other countries. Chronic pulmonary disease Management Unit is a management model connecting inpatient and outpatient treatment for asthma and COPD patients. Patients receive long-term management and full consultation to share experiences and be provided with necessary information about the disease.</p><p><strong>Objective: </strong>The main purpose was to evaluate the effectiveness of the unit for patients with COPD and asthma in Vietnam.</p><p><strong>Methods: </strong>A Combined cross-sectional study and retrospective longitudinal study was conducted in 310 COPD and asthma patients at Hai Duong, Bac Giang, Thai Nguyen. The questionnaires included 30 questions with two sections including sociodemographic data and using management and treatment services.</p><p><strong>Results: </strong>After 24 months of management and treatment, knowledge of the disease, medicine use, symptoms, range of activities, eating, sleeping status, and disease control of patients were improved better. For ACT score, the points increased by 2.1 points, 3.4 points, and 4 points, respectively. For the CAT score, the point reduced by 3.7 points, 6.4 points, and 9.1 points, respectively. Improved severe breathlessness efficiency index from 0.6% at 6 months to 9.5% after 24 months.</p><p><strong>Conclusion: </strong>Our findings suggest that the government need to invest in facilities, equipment, and human resources to maintain and replicate the CMU to help patients receive timely management and treatment, contributing to reducing treatment costs and improving quality of life for asthma and COPD patients.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"36 4","pages":"288-293"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11830226/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143443119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unveiling the Nexus: Depressive Symptoms and Medication Adherence in Hypertensive Patients' Self-care: A Systematic Review.","authors":"Theofilos Stamoulis, Elena Dragioti, Mary Gouva, Stefanos Mantzoukas, Michael Κourakos","doi":"10.5455/msm.2024.36.65-72","DOIUrl":"https://doi.org/10.5455/msm.2024.36.65-72","url":null,"abstract":"<p><strong>Background: </strong>Hypertension, a significant public health concern, is frequently linked to emotional disorders like depression. Research shows a reciprocal link between depression and hypertension, potentially influencing patients' adherence to self-care routines.</p><p><strong>Objective: </strong>This systematic review aimed to examine the association between depressive symptoms and aspects of self-care, with a focus on medication adherence in individuals diagnosed with hypertension.</p><p><strong>Methods: </strong>Following PRISMA guidelines, a systematic review was conducted by searching PubMed, PsycINFO and Scopus until March 17, 2023. The included studies involved quantitative primary research conducted in English, focusing on adults (≥18 years) diagnosed with hypertension and experiencing depressive symptoms. Observational studies were assessed using the Newcastle-Ottawa Scale, and randomized controlled trials were evaluated using the revised Cochrane Risk of Bias Tool (RoB 2.0). Due to the great diversity of these studies, a narrative synthesis of the results was undertaken. Results: A total of 18 studies involving 6,131 people with hypertension, that met our eligibility criteria were ultimately included. The reported rates of depressive symptoms ranged from 4% to 43%. Of these studies, nine reported a statistically significant association, showcasing an adverse impact of depressive symptoms on medication adherence. The remaining nine did not confirm the above.</p><p><strong>Conclusion: </strong>This systematic review highlights the diverse body of research exploring depressive symptoms and medication adherence among individuals with hypertension. The review suggests a need for increased attention to self-care practices, particularly in relation to adherence to antihypertensive medication. However, it recommends the conduction of more robust longitudinal studies to comprehensively explore this relationship.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"36 1","pages":"65-72"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10999142/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140864266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"OHCA in Bosnia and Herzegovina: Before and During the COVID-19 Pandemic.","authors":"Armin Sljivo, Arian Abdulkhaliq, Ahmed Mulac, Vlado Lukic, Ivona Margeta, Marija Rako, Emira Kapisazovic","doi":"10.5455/msm.2024.36.4-9","DOIUrl":"https://doi.org/10.5455/msm.2024.36.4-9","url":null,"abstract":"<p><strong>Background: </strong>Out-of-hospital cardiac arrest (OHCA) refers to the cessation of mechanical cardiac activity outside healthcare facilities which requires prompt intervention and intensive resuscitative efforts. The COVID-19 pandemic has caused significant disruptions to OHCA systems-of-care, adversely affecting every component of the chain of survival.</p><p><strong>Objective: </strong>The objective of this study was to examine the potential impacts of the COVID-19 pandemic on OHCA events, to draw comparisons between the period before and during the COVID-19 pandemic.</p><p><strong>Methods: </strong>This cross-sectional study encompassed data pertaining to all OHCA incidents attended to by the Emergency Medical Service of Canton Sarajevo, covering the period from January 2017 to December 2022, before and during the COVID-19 pandemic.</p><p><strong>Results: </strong>During observed period, a total of 1418 [796 (56.1%) before and 622 (43.9%) during COVID-19 pandemic] OHCA events have occurred in Canton Sarajevo of which 297 (20.9 %) [180 (12.7%) before and 117 (8.2%) during COVID-19 pandemic] obtained ROSC. After a 30-day period following the ROSC) it was observed that the predominant outcome, accounting for 181 (12.7%) [106 (7.4%) before and 75 (5.2%) during COVID-19 pandemic] of cases, was a complete recovery. An examination before and during COVID-19 pandemic revealed a decline in OHCA during the year 2021 and 2022 when COVID-19 pandemic was at its highest in the country Being younger, quicker EMT response time and individuals with the initial rhythm of VF or VT were significantly associated with obtaining ROSC (p<0.05). Only 48 (3.3%) of 1418 OHCA events were assisted by bystanders There was no report of AED usage.</p><p><strong>Conclusion: </strong>In conclusion, our investigation highlights the impact of the COVID-19 pandemic on OHCA events in Canton Sarajevo, revealing a decrease in OHCA incidence and a reduction in cases achieving ROSC. Notably, EMT response time was shorter during the pandemic.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"36 1","pages":"4-9"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10999140/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140873015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Importance of Nursing Management for Patients with Internal Diseases in Albania.","authors":"Rajmonda Milloshi, Aida Zotaj Lako","doi":"10.5455/msm.2024.36.294-299","DOIUrl":"10.5455/msm.2024.36.294-299","url":null,"abstract":"<p><strong>Background: </strong>Nursing management is essential in the care of patients with internal diseases, supporting disease management, health promotion, and patient education.</p><p><strong>Objective: </strong>This study examines the impact of effective nursing management on patient outcomes in Albania.</p><p><strong>Methods: </strong>Data was collected from 175 patients diagnosed with various internal diseases across healthcare facilities. Participants were divided into two groups based on the nursing management approach received. Group A received standard nursing care, while Group B received enhanced nursing interventions, including structured patient education, medication management, and coordinated care. The effectiveness of these interventions was evaluated through a pre- and post-intervention design, assessing patient compliance, health outcomes, and satisfaction levels. Descriptive statistics were applied using SPSS software, with chi-square tests to compare groups and multiple regression analysis to explore relationships between nursing management practices and patient outcomes.</p><p><strong>Results: </strong>Results showed that patients in Group B who received enhanced nursing management had significantly improved treatment adherence compared to Group A. The mean compliance rate increase was 30% higher in Group B.</p><p><strong>Conclusion: </strong>This study highlights the critical role of nursing management in managing internal diseases in Albania and supports the need for enhanced training and resources for nursing professionals to adopt comprehensive management strategies. Prioritizing effective nursing management can lead to better patient outcomes, improved health, and quality of life for individuals with chronic and acute internal conditions.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"36 4","pages":"294-299"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11830225/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143443076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Role of TP53, KRAS, CDH1, Demographic and Clinical Variables in Gastric Cancer.","authors":"Ali Abu Siyam, Suha Khayri Ababneh, Ibrahim Al-Odat, Sokiyna Ababneh, Ahed J Alkhatib","doi":"10.5455/msm.2024.36.280-287","DOIUrl":"10.5455/msm.2024.36.280-287","url":null,"abstract":"<p><strong>Background: </strong>Worldwide, gastric cancer remains the fifth most prevalent type of cancer and is the third leading cause of cancer-related deaths. Gastric cancer is responsible for around 7% of global cancer occurrence and approximately 9% of annual cancer-related mortalities.</p><p><strong>Objective: </strong>The aim of the study was to analyze gastric cancer dataset posted on Kaggle (https://www.kaggle.com/datasets/datasetengineer/gastric-cancer-gc-dataset).</p><p><strong>Methods: </strong>This dataset comprises 212354 participants, of whom 10% had gastric cancer. This dataset was analyzed to extract the information regarding gastric cancer. The analysis of data was performed SPSS version 25. Descriptive analysis was used to describe data including frequency and percentages to describe categorical variables such as age, and the mean and standard deviation to describe non-categorical variables such as age. The relationships between variables and gastric cancer were calculated based on Chi-Square and One Way ANOVA tests, significance was considered if p value ≤0,05.</p><p><strong>Results: </strong>The mean age was 53.2580±18.98 years. Seventy percent of participants were males. About 30% of participants had a family history of gastric cancer. About 40% of participants were smokers. About 50% of participants were alcoholic. About 75% of participants had Helicobacter pylori. 80% of participants were at high salt intake. About 50% of participants had chronic gastritis. Abnormal endoscopic image reports were reported in approximately 30% of participants. Biopsy results were negative in 90% of participants. The reports of CT scans were negative in approximately 80%. Genetic mutations were detected in Tp53 (50.1%), KRAS (20%), and CDH1 (29,9%). No significant relationships were found between gastric cancer and study variables.</p><p><strong>Conclusion: </strong>Most of the people had risk factors such as Helicobacter pylori infection, salt intake, and mutations in TP53, KRAS, and CDH1. However, statistical analyses did not find significant correlations between those and gastric cancer.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"36 4","pages":"280-287"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11830230/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143443125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}