Materia socio-medica最新文献

{"title":"Analysis of the Impact of Independent Factors on the Score - Mental Health Scale of the SF-36 Questionnaire in Hypertensive Patients Who Recovered from COVID-19.","authors":"Samela Zelic, Ediba Celic-Spuzic, Senada Dzebo, Hasiba Erkocevic, Natasa Trifunovic, Adnan Cejvan, Amra Macic-Dzankovic","doi":"10.5455/msm.2025.37.231-235","DOIUrl":"10.5455/msm.2025.37.231-235","url":null,"abstract":"<p><strong>Background: </strong>The COVID-19 pandemic has significantly affected people's lifestyles, particularly influencing existing chronic conditions such as hypertension. It is estimated that 1.28 billion adults aged 30-79 worldwide have hypertension. In addition to its impact on blood pressure levels, the pandemic also affected the quality of life and mental health of hypertensive patients. Mental health among individuals with chronic diseases who have recovered from COVID-19 is an important and complex issue. Research indicates that these patients are at a considerably higher risk of developing anxiety, depression, and PTSD, as well as experiencing deterioration of their underlying conditions.</p><p><strong>Objective: </strong>The aim of this study was to analyze the impact of independent factors on the mental health score using the SF-36 questionnaire among hypertensive patients who recovered from COVID-19.</p><p><strong>Methods: </strong>A cross-sectional study was conducted in selected primary healthcare centers across four cantons in the Federation of Bosnia and Herzegovina (FBiH). The study included a total of 240 patients, randomly selected from those diagnosed with hypertension who had recovered from COVID-19 (experimental group, n = 120). The control group consisted of 120 participants who had recovered from COVID-19 but did not have hypertension. The European SF-36 questionnaire was used for longitudinal self-assessment of health status in patients with various chronic conditions.</p><p><strong>Results: </strong>The analysis of independent factors affecting mental health during the COVID-19 pandemic showed poorer mental health outcomes among older, single participants with higher educational attainment. In relation to COVID-19 treatment, patients who had been hospitalized or treated in Intensive Care Units and who experienced cardiac complications exhibited worse mental health scores.</p><p><strong>Conclusion: </strong>The findings of this study indicate a statistically significant higher likelihood of poorer mental health among hypertensive patients who had contracted COVID-19.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"37 3","pages":"231-235"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12858271/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146109343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alchemilla Vulgaris Compounds as Inhibitors of HPV 16 E6 Oncoprotein: Quercetin with Promising in Silico Potential.","authors":"Emir Sehercehajic, Berina Hasanefendic, Aleksandra Pasic, Emina Smajic","doi":"10.5455/msm.2025.37.184-190","DOIUrl":"10.5455/msm.2025.37.184-190","url":null,"abstract":"<p><strong>Background: </strong>The oncogenic potential of HPV remains a major global public health challenge and various natural therapeutics are being investigated to prevent cancer. The natural components of the Alchemilla vulgaris plant have various anti-inflammatory, antioxidant, antiviral, and anticancer effects.</p><p><strong>Objective: </strong>Therefore, the aim of this study was to bioinformatically examine the potential inhibitory effect of A. vulgaris compounds on the HPV target protein.</p><p><strong>Methods: </strong>The structures of quercetin, catechin, apigenin, luteolin, caffeic and gallic acid were taken from the PubChem database, and the protein structure of the target HPV 16 E6 oncoprotein (PDB ID: 4XR8) from the Protein Data Bank. Virtual screening and docking analysis were performed in AutoDock Vina. Protein-ligand complexes were visualized using Discovery Studio. The molecular dynamics simulation of 4XR8 in complex with quercetin was performed using Desmond.</p><p><strong>Results: </strong>Docking analysis showed that quercetin has the strongest binding affinity with 4XR8 (quercetin -8.9 kcal/mol, apigenin -8.7 kcal/mol, luteolin -8.7 kcal/mol, catechin -8.4 kcal/mol, caffeic acid -7.3 kcal/mol, gallic acid -6.8 kcal/mol). The molecular dynamics simulation results reinforce the stability and strong binding affinity of quercetin within the HPV 16 E6 oncoprotein.</p><p><strong>Conclusion: </strong>Natural components of Alchemilla vulgaris, especially quercetin, have shown promising potential for the treatment of HPV infection and additional in vitro and in vivo studies are needed for their further research.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"37 3","pages":"184-190"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12858261/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146109409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Influence of Gender and Length of Therapy Use on Sleep Quality in Patients with Parkinson's Disease.","authors":"Zikrija Dostovic, Nermin Mesic, Nerimana Suljkanovic, Denisa Salihovic","doi":"10.5455/msm.2025.37.58-63","DOIUrl":"10.5455/msm.2025.37.58-63","url":null,"abstract":"<p><strong>Background: </strong>Normal sleep duration is crucial for maintaining brain homeostasis. Sleep disorders in Parkinson's disease are numerous, multifactorial, and result in significant morbidity.</p><p><strong>Objective: </strong>The aim of the study was to investigate the association between gender and the duration of therapy on sleep quality in patients with Parkinson's disease.</p><p><strong>Methods: </strong>The study is prospective, and includes 40 consecutively hospitalized patients with verified Parkinson's disease. The study included subjects of both genders and all age groups. To analyze the data on the subjects, we used: medical histories, nursing documentation of patients, a questionnaire with sociodemographic data, and the Parkinson's Disease Sleep Assessment Scale. We divided all subjects into two groups: subjects who have been using therapy for up to 5 years and those who have been using therapy for more than 5 years.</p><p><strong>Results: </strong>Among subjects who have been taking medication for less than 5 years, 33.3% were female and 66.6% were male. Of the total number of respondents who have been taking therapy for more than 5 years, 36.3% are female and 63.6% are male. The duration of the therapy has a statistically significant effect on the quality of sleep in patients with Parkinson's disease (p < 0.05). The subject's gender does not have a significant independent influence on the quality of sleep in patients with Parkinson's disease (p > 0.05). The interaction of gender and length of therapy use has no significant separate effect on the quality of sleep in Parkinson's disease patients (p > 0.05). The quality of sleep is better in male and female subjects who take the therapy until the age of 5.</p><p><strong>Conclusion: </strong>The duration of therapy use has a significant impact on the quality of sleep in Parkinson's disease patients. The gender of the subject has no significant independent influence on the quality of sleep in patients with Parkinson's disease.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"37 1","pages":"58-63"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11910904/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143652883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Infertility - a Great Challenge of the Past, Present, and Future.","authors":"Ivana Erceg Ivkosic, Jana Mesic, Rajko Fures, Zlatko Hrgovic, Luka Bulic, Eva Brenner, Vesna Cosic, Blazenka Miskic, Dinko Kolaric","doi":"10.5455/msm.2025.37.74-79","DOIUrl":"10.5455/msm.2025.37.74-79","url":null,"abstract":"<p><strong>Background: </strong>The Infertility refers to the inability of couples to conceive after 12 months of regular, unprotected sexual intercourse. The incidence of infertility is increasing and is estimated to be 8-12%, or even up to 20%. Primarily, it involves organic causes, but the psychological aspect is not excluded.</p><p><strong>Objective: </strong>The aim of this article was to discrabe the observing of various causes of infertility.</p><p><strong>Methods: </strong>Authors used, as sources, published relevant facts in the articles deposited in important scientific indexed databases Medline, Scopus, PubMed Central, Hinari, etc. to write this review.</p><p><strong>Results and discussion: </strong>The diagnosis of female infertility involves a detailed medical history, laboratory tests, hormonal evaluation, and imaging studies such as ultrasound and eventually hysteroscopy and laparoscopy. Advances in genetic testing have deepened our understanding of infertility origins in both genders. Sperm analysis is pivotal for diagnosing male infertility. Infertility treatment includes identifying causes and applying various therapies, including conservative surgical, and assisted reproductive technology (ART).</p><p><strong>Conclusion: </strong>The currently used ART methods include ovulation tracking with planned intercourse, insemination and in vitro fertilization (IVF).</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"37 1","pages":"74-79"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11910897/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143652808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reduction of Serum Interleukin-17 and Interleukin-23 Levels Following Narrow Band Ultraviolet B Treatment in Patients with Moderate-to-severe Psoriasis Vulgaris.","authors":"Pham Thi Minh Phuong, Tran Thi Huyen, Quach Thi Ha Giang, Trinh Minh Trang, Hoang Thi Phuong, Le Thi Hai Yen, Nguyen Van Thuong, Le Huu Doanh","doi":"10.5455/msm.2025.37.125-130","DOIUrl":"10.5455/msm.2025.37.125-130","url":null,"abstract":"<p><strong>Background: </strong>Psoriasis, a common skin disorder, involves immune cells and cytokines in its pathogenesis. Narrow band ultraviolet B (NB-UVB) treatment has demonstrated efficacy and safety in managing this condition.</p><p><strong>Objective: </strong>This study aimed to assess changes in serum interleukin (IL)-17, IL-23, and tumor necrosis factor-alpha (TNF-α) levels during NB-UVB treatment for psoriasis vulgaris.</p><p><strong>Methods: </strong>An interventional, pre-post comparative study was conducted on patients with moderate to severe psoriasis vulgaris undergoing NB-UVB treatment. Patients were randomly allocated to Group 1 (n=39) receiving NB-UVB based on minimal erythema dose (MED) and Group 2 (n=32) based on Fitzpatrick skin type classification. Serum IL-17, IL-23, and TNF-α levels were measured before treatment and upon achieving PASI75.</p><p><strong>Results: </strong>There were no significant differences in serum IL-17, IL-23, and TNF-α levels between Group 1 and Group 2 at either time point. In Group 1, IL-17 levels decreased from median 2.6 pg/ml before treatment to 2.5 pg/ml at PASI75 (P=0.0107). In Group 2, IL-23 levels decreased from median 9.6 pg/ml pre-treatment to 1.3 pg/ml at PASI75 (P<0.0190). Across all patients, pre-treatment IL-17 and IL-23 levels (median 2.6 pg/ml and 7.1 pg/ml, respectively) were significantly higher compared to levels at PASI75 (P=0.0349 and P=0.0023, respectively).</p><p><strong>Conclusion: </strong>NB-UVB effectively treats moderate to severe psoriasis vulgaris, leading to reduced serum IL-17 and IL-23 levels irrespective of MED-based or skin type-based dosing strategies.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"37 2","pages":"125-130"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12212219/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144556317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of an Online Teaching Program on Critical Care Nurses' Knowledge and Attitude Regarding Obstructive Sleep Apnea (OSA) in Saudi Arabia: a Quasi-Experimental Study.","authors":"Hanan Alruwaythi, Rana Ali Alameri, Afnan Hamad Al Swyan, Fayza Ahmed Kosman","doi":"10.5455/msm.2025.37.334-340","DOIUrl":"10.5455/msm.2025.37.334-340","url":null,"abstract":"<p><strong>Background: </strong>Adequate knowledge and positive attitudes toward OSA are essential for critical care nurses to identify and manage this underdiagnosed condition. Structured educational interventions can bridge knowledge gaps and enhance clinical confidence, ultimately improving patient outcomes.</p><p><strong>Objective: </strong>The aim of this study was to evaluate the impact of an online educational program on critical care nurses' knowledge and attitudes toward obstructive sleep apnea (OSA). Design of this study was Quasi-experimental pre-test/post-test study.</p><p><strong>Methods: </strong>Critical care nurses in Saudi Arabia participated in an online teaching program delivered via Zoom. Data were collected using the validated OSA Knowledge and Attitude (OSAKA) questionnaire pre- and post-intervention. Statistical analysis included the Wilcoxon Signed-Rank Test and correlation assessments.</p><p><strong>Results: </strong>Of the 54 participants, only 8.3% demonstrated adequate OSA knowledge pre-intervention, compared to 51.7% post-intervention. Median knowledge scores significantly improved (Z = 5.955, p = 0.000). Attitude scores also increased, with participants reporting enhanced confidence in identifying at-risk patients (mean = 4.3, SD = 0.72) and managing CPAP therapy (mean = 4.467, SD = 0.566). Training showed a significant positive correlation with post-test attitudes (ρ = 0.286, p = 0.030).</p><p><strong>Conclusion: </strong>The study highlights the effectiveness of structured educational programs in improving OSA knowledge and attitudes among critical care nurses. Integrating such training into nursing curricula and continuing education is recommended to enhance patient care quality.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"37 4","pages":"334-340"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12923287/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147273021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Manifestation of Necrotic Palatal Ulceration in COVID-19 Infection: a Case Report.","authors":"Mimoza Canga, Alketa Qafmolla, Edit Xhajanka, Irene Malagnino","doi":"10.5455/msm.2025.37.80-82","DOIUrl":"10.5455/msm.2025.37.80-82","url":null,"abstract":"<p><strong>Background: </strong>The global pandemic caused by the COVID-19 virus is a serious disease that has significantly affected the lives of millions of people.</p><p><strong>Objective: </strong>The objective of this case study is to describe the development of a necrotic ulcer on the palate in a COVID-19 patient.</p><p><strong>Case presentation: </strong>This is the clinical case of a 35-year-old male patient with a 20-year history of two pack-a-day smoking who contracted COVID-19. He was admitted to the Department of Oral and Maxillofacial Surgery at the \"Mother Teresa\" University Hospital Center in Tirana, Albania, presenting with oral pain, facial swelling, and necrosis in the palatal region and the lower lip.</p><p><strong>Conclusion: </strong>This case report from Albania is significant as it presents an ulcer with necrotic tissue located in the hard palate region of a patient infected with SARS-CoV-2.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"37 1","pages":"80-82"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11910900/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143652814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Diagnostic Significance of the Tumor Marker CYFRA 21-1 in Patients with Laryngeal Carcinoma.","authors":"Lejla Tokic, Sefik Hasukic, Fuad Brkic, Sekib Umihanic, Fatima Hukic, Selveta Mustafic","doi":"10.5455/msm.2025.37.131-135","DOIUrl":"10.5455/msm.2025.37.131-135","url":null,"abstract":"<p><strong>Background: </strong>Laryngeal squamous cell carcinoma (LSC) is the leading malignant tumour of the head and neck. Establishing new biomarkers is extremely important because they can be important for early diagnosis and prognosis of LSC.</p><p><strong>Objective: </strong>The aim of this study was to establish the significance of cytokeratin fragment antigen 21-1 (CYFRA 21-1) in the early diagnosis and prognosis of LSC.</p><p><strong>Methods: </strong>This was prospective research involving 35 patients of both sexes with pathohistologically confirmed LSC, who were treated in the period from 2022 to 2024. The control group consisted of 30 patients who underwent surgery for other non-malignant diseases and who had a normal indirect laryngoscopy findings. The levels of CYFRA 21-1 were determined for three time periods: preoperative, four weeks after surgery, and three months after radiotherapy or concomitant chemoradiotherapy. For the statistical analysis of data we used descriptive statistics methods, the Student T-test and the χ2 test to calculate the significance of the tested differences, where differences on the level of p<0.05 were considered to be statistically significant.</p><p><strong>Results: </strong>Statistically significantly higher mean serum levels of CYFRA 21-1 were found preoperatively in the experimental group in comparison with the control group (p<0.001). Statistically significant lower levels of CYFRA 21-1 were found four weeks after surgery in the experimental group in comparison with preoperative levels (p=0.004). A statistically significant decrease in serum levels of CYFRA 21-1 was also found three months after radiotherapy or concomitant chemoradiotherapy in comparison with the preoperative levels (p=0.001). The serum levels of CYFRA 21-1 were statistically significantly higher preoperatively in patients with stage III/IV of the disease in comparison with stage I/II (p<0.001).</p><p><strong>Conclusion: </strong>Increased levels of CYFRA 21-1 are a significant indication of the presence of LSC, especially in patients with advanced stages of the disease.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"37 2","pages":"131-135"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12212222/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144556319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aphasia in Patients with Intracranial Tumors.","authors":"Jasmina Klebic, Mirela Duranovic, Emir Tupkovic, Rusmir Softić, Senada Selmanović, Anida Sehanovic, Amila Tokic, Nedim Srabovic","doi":"10.5455/msm.2025.37.220-223","DOIUrl":"10.5455/msm.2025.37.220-223","url":null,"abstract":"<p><strong>Background: </strong>Aphasia is an acquired communication disorder that affects language comprehension and production, typically occurring after brain damage. It is a frequent clinical manifestation of both benign and malignant brain tumors, particularly when lesions are localized in language-dominant areas.</p><p><strong>Objective: </strong>To assess the prevalence and characterize the types of aphasia in patients with intracranial tumors, emphasizing its clinical significance and the importance of early speech-language evaluation.</p><p><strong>Methods: </strong>This prospective study included patients with confirmed brain tumors diagnosed through neuroimaging (CT or MRI of the neurocranium), who were hospitalized at the Clinic of Neurosurgery, University Clinical Center Tuzla, over a one-year period. Patients with pre-existing aphasia of any etiology, as well as those who had not acquired reading and writing skills, were excluded. All assessments were performed prior to surgical intervention using the Boston Diagnostic Aphasia Examination.</p><p><strong>Results: </strong>Aphasia was diagnosed in 25 patients (27.5%). The most common type was anomic aphasia in 10 patients (40%), followed by Broca's aphasia in 7 patients (28%), transcortical motor aphasia in 3 patients (12%), and transcortical sensory aphasia in 1 patient (4%). The highest number of patients with aphasia had tumors localized in the left temporal lobe, followed by the parietal and temporoparietal regions.</p><p><strong>Conclusion: </strong>Aphasia is a common clinical finding in patients with intracranial tumors, affecting more than one-quarter of the studied population. The distribution of aphasia types is consistent with the localization of lesions in language-dominant areas, particularly the left temporal lobe. Early recognition and detailed speech-language assessment are essential for timely intervention, rehabilitation planning, and optimizing functional outcomes.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"37 3","pages":"220-223"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12858259/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146109383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Frequency of Fals and Degree of Diability in Stroke Patients.","authors":"Zikrija Dostovic, Nermin Mesic, Mirza Moranjkic, Hasad Imamovic, Suljo Kunic, Denisa Salihovic, Kenan Galijasevic","doi":"10.5455/msm.2025.37.164-168","DOIUrl":"10.5455/msm.2025.37.164-168","url":null,"abstract":"<p><strong>Background: </strong>Stroke patients have significant disability and an increased risk of falling.</p><p><strong>Objective: </strong>To determine the incidence of falls and the degree of disability in stroke patients and to determine the correlation of falls with the degree of disability.</p><p><strong>Methods: </strong>This is a prospective study of 100 stroke patients confirmed by computed tomography and magnetic resonance imaging of the brain. We used a demographic questionnaire together with the Glasgow Coma Scale, Stroke Assessment Scale, Rankin Scale and Morse Scale to collect data and analyzed them using SPSS 17, including statistical measures, including Pearson correlation.</p><p><strong>Results: </strong>Hemorrhagic stroke patients had a higher incidence of falls (p = 0.06). There was no difference in the incidence of falls according to the gender of the patients (p = 0.07). Older people had a higher frequency of falls, and women and patients with hemorrhagic stroke had a higher risk of falling (p = 0.2). Patients with a stroke in the area of the anterior circulation were statistically significantly more disabled (p < 0.05). A weak positive correlation was calculated between the frequency of falls of patients after stroke and the degree of disability (r = 0.08, n = 94, p = 0.4). Stroke patients who also had atrial fibrillation as a comorbidity had a statistically significantly higher frequency of falls compared to patients with other comorbidities (p = 0.02).</p><p><strong>Conclusion: </strong>Patients with hemorrhagic stroke have a higher frequency of falls. Women, elderly people, patients with a stroke in the area of the anterior circulation and with atrial fibrillation as a comorbidity are statistically significantly more disabled after a stroke. There is a positive correlation between the frequency of falls in patients after a stroke and the degree of disability.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"37 2","pages":"164-168"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12212237/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144556311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}