Materia socio-medica最新文献

{"title":"Clinical Evaluation and Microbiological Identification of Helicobacter Pylori in Patients with Oral Ulcerations Using the Polymerase Chain Reaction (PCR) Method.","authors":"Arma Muharemovic, Sanja Hadzic, Enes Pasic, Indira Mujic Jahic, Mirjana Gojkov Vukelic, Anisa Zoronjic, Mia Hodzic","doi":"10.5455/msm.2025.37.48-53","DOIUrl":"10.5455/msm.2025.37.48-53","url":null,"abstract":"<p><strong>Background: </strong>The etiology of oral ulceration is multicausal with numerous predisposing factors. Studies by various authors cite Helicobacter pylori infection as a possible cause of certain oral ulcerations.</p><p><strong>Objective: </strong>The aim of the study is to prove the presence of Helicobacter pylori in the oral cavity of patients with oral ulcerations, as well as to examine the relationship between the presence of Helicobacter pylori in the oral cavity and the development of oral ulcerations.</p><p><strong>Methods: </strong>The study included regular patients at the Department and Clinic of Oral Medicine and Periodontology, Faculty of Dental Medicine, University of Sarajevo, suffering from oral ulcerations, as well as healthy patients without oral diseases. The diagnosis of oral ulceration is based on a thorough history, clinical examination, and exclusion of other oral diseases. All patients were taken anamnestic data on the existence of digestive system diseases, and by reviewing medical documentation, a previously diagnosed digestive system disease by a gastroenterologist was recorded. A cytological smear was taken in all 80 cases, in patients with ulcerative lesions a smear was taken from the lesion and in healthy subjects from the mucous membrane of the palate, cheek and tongue. Highly sensitive and specific polymerase chain reaction (PCR) was used to determine the presence of Helicobacter pylori in the oral cavity and oral lesions.</p><p><strong>Results: </strong>The results of our study showed that there is no statistically significant difference between the presence of Helicobacter pylori in the oral cavity of patients with oral ulcerations and subjects with healthy mucosa.</p><p><strong>Conclusion: </strong>Helicobacter pylori is not a risk factor for the development of oral ulcerations and can be found on the oral mucosa as a transient pathogen.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"37 1","pages":"48-53"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11910898/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143652797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality of Life of Patients After Nasal Septoplasty.","authors":"Cuong Vi Viet, Son Dao Anh, Hung Quoc Pham","doi":"10.5455/msm.2025.37.43-47","DOIUrl":"10.5455/msm.2025.37.43-47","url":null,"abstract":"<p><strong>Background: </strong>Nasal obstruction was a common symptom encountered in otolaryngology, arising from various etiologies, including both mucosal and structural factors.</p><p><strong>Objective: </strong>The aim of this study was to evaluate the quality of life of patients after nasal septoplasty.</p><p><strong>Methods: </strong>A prospective, longitudinal 6-month study was conducted on 52 patients who underwent septoplasty or rhinoplasty and were followed up at Hanoi Medical University Hospital from April 2023 to April 2024. The effectiveness of the surgery was assessed through clinical nasal symptoms, and the quality of life of patients was evaluated using the SF-36 Quality of Life Assessment Tool (Short Form-36).</p><p><strong>Results: </strong>In the study group, 27 (51.9%) patients were female. The nasal obstruction scores significantly decreased from preoperative (2.67 ± 0.47) to 1 month (1.1 ± 0.75) and 6 months (0.65 ± 0.68) postoperative (p<0.05). The facial pain scores significantly decreased from preoperative (1.46 ± 1.11) to 1 month (1.1 ± 1.05) and 6 months (0.79 ± 0.89) postoperative (p<0.05). The rhinitis scores significantly decreased from preoperative (1.42 ± 1.11) to 1 month (1.02 ± 1) and 6 months (0.77 ± 0.9) postoperative (p<0.05). The average quality of life scores according to the 8 factors of the SF-36 Quality of Life Assessment Tool increased at 1 month and 6 months postoperative. The differences were statistically significant (p<0.05).</p><p><strong>Conclusion: </strong>Nasal septoplasty significantly improves clinical symptoms and the quality of life of patients. The SF-36 is a reliable outcome measure for the success of nasal septal surgery.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"37 1","pages":"43-47"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11910906/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143652876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anthropometric Data by Using Bioelectrical Analysis as a Parameters for New Classification and Definition of Obesity.","authors":"Nizama Salihefendic, Muharem Zildzic, Izet Masic, Slobodan M Jankovic","doi":"10.5455/msm.2024.37.11-17","DOIUrl":"10.5455/msm.2024.37.11-17","url":null,"abstract":"<p><strong>Background: </strong>The prevalence of obesity and obesity-related clinical conditions, including metabolic-associated steatotic liver disease (MASLD), sarcopenia, and a wide spectrum of pathological manifestations, is rising globally. According to WHO, BMI is the only anthropometric measure currently used to classify obesity, overweight, and underweight. However, emerging research suggests that obesity is a complex pathological state influenced by multiple etiological factors. Given the limitations of BMI, there is a growing need for a more comprehensive assessment of body composition, particularly fat mass quantity and distribution. Bioelectrical impedance analysis (BIA) provides valuable anthropometric data that can help differentiate obesity phenotypes and guide improved therapeutic approaches.</p><p><strong>Objective: </strong>This study aims to analyze body composition using BIA in a randomly selected sample of adults from primary healthcare settings in Bosnia and Herzegovina. The primary goal is to assess total body weight, fat mass quantity, fat distribution, and obesity types prevalent in this population. Additionally, the study seeks to establish reference values for further diagnostic, preventive, and therapeutic strategies to improve public health outcomes.</p><p><strong>Methods: </strong>A cross-sectional study was conducted on adults (≥18 years) in Gračanica, Bosnia & Herzegovina (B6H), from January 2021 to January 2025. Inclusion criteria required participants to provide signed informed consent, while exclusion criteria included acute systemic diseases, severe dehydration, and fasting for more than 24 hours. Anthropometric parameters measured included age, height, weight, BMI, body fat mass (BFM), fat-free mass (FFM), percent body fat (PBF), waist-hip ratio (WHR), and bone mineral content (BMC). Data were analyzed using SPSS (version 18), with results presented as medians, interquartile ranges, and percentiles (5th, 25th, 50th, 75th, and 95th).</p><p><strong>Results: </strong>A total of 4,628 adults participated in the study, of whom 2,824 (61.0%) were female and 1,804 (39.0%) were male. The median age was 45 years (IQR: 29 years). The findings revealed that over one-quarter of the B&H population is obese, with abdominal obesity being the predominant type. This phenotype is associated with the highest risk for metabolic syndrome and MASLD.</p><p><strong>Conclusion: </strong>Our study highlights a high prevalence of obesity among the examined individuals in primary care settings in B&H, with abdominal obesity being the most common type. This phenotype is strongly associated with metabolic complications. BIA-derived parameters of fat distribution and visceral fat mass may serve as valuable tools for improving obesity classification and developing more effective preventive and therapeutic strategies.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"37 1","pages":"11-17"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11910903/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143652941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fine Needle Aspiration Cytology of Lymph Nodes in Metastatic Cancer and Lymphoma: Our Single-institution Experience.","authors":"Sanela Vesnic, Anes Joguncic, Vesna Sarajlic, Mirsad Doric","doi":"10.5455/msm.2024.36.18-22","DOIUrl":"https://doi.org/10.5455/msm.2024.36.18-22","url":null,"abstract":"<p><strong>Background: </strong>Lymphadenopathy is a common finding in clinical practice. The cause of enlarged nodes on clinical examination alone is challenging and there may be multiple reasons for this enlargement. It may become enlarged due to stimulation by infectious agents or the involvement of metastasis or malignant diseases, such as lymphoma.</p><p><strong>Objective: </strong>The aim of the study was to investigate the diagnostic role of fine needle aspiration cytology of lymph nodes in metastatic cancer and lymphoma.</p><p><strong>Methods: </strong>A total of 48 FNAC lymph nodes suspicious for malignancy were sampled with follow-up biopsy in Clinical Center of University of Sarajevo from 2017 to 2023. Lymph nodes were aspirated using 20-22 G needle with minimally 2 passes, spread on slides, air-dried, stained with May-Grünwald-Giemsa or Papanikolaou and residual material sent for cytoblock.</p><p><strong>Results: </strong>Out of 48 cytological samples, 30 (62.5%) revealed metastatic epithelial cells and 12 (25%) lymphoproliferative neoplasm. Three samples were suspected for malignancies, one sample was unrepresentative, one inconclusive and one falsely negative. Histopathological confirmation had 35 patients, while others were confirmed based on clinical presentation and radiological techniques. Compared to histopathological diagnosis, cytology had a sensitivity of 89.47%, specificity of 93.33%, positive predictive value (PPV) 95.04% and negative predictive values (NPV) 86.13% for epithelial metastatic cancer. The overall diagnostic test accuracy was 91.06%. For lymphoproliferative neoplasms cytology in comparison to histopathology had sensitivity 85.71%, specificity 91.18%, PPV 76.4% and NPV 95.04%. The overall diagnostic test accuracy was 89.81%. In both ways cytology is showing significant possibility to be used as a primary tool in detecting cancers.</p><p><strong>Conclusion: </strong>FNAC is a fast, reliable, and efficient method for diagnosing malignant lymphadenopathy. The cytological diagnosis can sometimes be accepted as the definitive diagnosis without further correlation with histopathology, especially in advanced malignancies and known primary malignancies.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"36 1","pages":"18-22"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10999137/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140859488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characteristics and Related Factors of Bacterial Infection Among Patients With Cirrhosis.","authors":"Nguyen-Thi Ngoc Lan, Dau Quang Lieu, Tran Ngoc Anh, Le Hoai Thuong, Tran-Thi Khanh Tuong, Mai Hong Bang","doi":"10.5455/msm.2024.36.90-96","DOIUrl":"https://doi.org/10.5455/msm.2024.36.90-96","url":null,"abstract":"<p><strong>Background: </strong>Infection causes cirrhosis to decompensate, affecting liver function and resulting in several complications, including esophageal variceal hemorrhage, hepatic encephalopathy, and hepatorenal syndrome. Objective: This study aimed to identify the prevalence, essential features, and related factors of bacterial infection among patients with cirrhosis in Vietnam.</p><p><strong>Methods: </strong>This retrospective study included 317 patients diagnosed with cirrhosis, who were divided into two groups: group 1 including 125 patients with bacterial infection and group 2 including 192 patients without bacterial infection. Infection was diagnosed on the basis of its localization.</p><p><strong>Results: </strong>Spontaneous bacterial peritonitis (SBP; 31.2%) and pneumonia (28.8%) were the most common infections identified. The procalcitonin (PCT) level had a strong diagnostic value with an area under the curve value of 0.868. The most common type of gram-negative bacteria was Escherichia coli, while the gram-positive bacteria seen were Staphylococcus, Enterococcus, and Streptococcus among the patients with infection. In the logistic regression analysis, Child-Pugh class B and C (p<0.001, OR=4.14, CI=1.90-9.03; OR=4.76, CI=2.03-11.16, respectively) and the presence of acute kidney injury (p=0.009, OR=2.57, CI=1.27-5.22) and gastrointestinal hemorrhage (p=0.035, OR=0.39, CI=0.16-0.94) significantly differed between the groups.</p><p><strong>Conclusion: </strong>The most prevalent type of bacterial infection in patients with cirrhosis is SBP, with gram-negative bacteria being the most common cause. The PCT level is useful in identifying infection in patients with cirrhosis. Decompensated cirrhosis is linked to a higher risk of infection.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"36 1","pages":"90-96"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10999149/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140859483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Role of Law Enforcement Mechanisms in the Care of Occupational Health and Safety in the Workplace of Health Professionals in Kosovo.","authors":"Albina Xhemajli, Naser Rugova, Doncho Donev","doi":"10.5455/msm.2024.36.187-191","DOIUrl":"https://doi.org/10.5455/msm.2024.36.187-191","url":null,"abstract":"<p><strong>Background: </strong>Workplace health and safety are critical concerns for healthcare professionals, who are often exposed to various occupational hazards.</p><p><strong>Objective: </strong>The aim of the study was to analyze the effectiveness and impact of law enforcement mechanisms in ensuring occupational health and safety for healthcare professionals in Kosovo.</p><p><strong>Methods: </strong>Consist in conduct research on the role of law enforcement mechanisms in ensuring the occupational health and safety of healthcare professionals in Kosovo, using a qualitative methodology with questionnaires targeting the Health Inspectorate and Labor Inspectorate.</p><p><strong>Results: </strong>The study found that while laws and regulations for workplace safety in healthcare exist in Kosovo, their enforcement is inconsistent and often inadequate.</p><p><strong>Conclusion: </strong>The study concludes that the enforcement of workplace health and safety laws in Kosovo's healthcare sector is inadequate, leading to unsafe working conditions for healthcare professionals.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"36 3","pages":"187-191"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11693137/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142924392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Attitudes of Breastfeeding Mothers and Healthcare Professionals About Breastfeeding.","authors":"Tomica Kukina Zvigac, Rajko Fures, Zlatko Hrgovic, Damir Rosic, Lucije Radic, Albert Despot, Kresimir Zivkovic, Suzana Pekez","doi":"10.5455/msm.2024.36.300-304","DOIUrl":"10.5455/msm.2024.36.300-304","url":null,"abstract":"<p><strong>Background: </strong>The attitudes of breastfeeding mothers and healthcare professionals greatly influence decisions about initiation of breastfeeding, duration of breastfeeding, and repeated breastfeeding in multiparous women.</p><p><strong>Objective and methods: </strong>This research aimed to examine, through a questionnaire, the attitudes of breastfeeding mothers and healthcare professionals about breastfeeding in the area covered by the district nurses of the Zagreb-West Health Center. 76 mothers and 74 healthcare professionals participated in the study, which was conducted during 2021.</p><p><strong>Results: </strong>All healthcare professionals (100%) believe that breastfeeding in the first 6 months is important, and 97% of them believe that they are adequately educated about proper breastfeeding techniques. Furthermore, 98% of them believe that they provide mothers with all the necessary help and support regarding breastfeeding. 93% of healthcare professionals support breastfeeding in public. Most breastfeeding mothers were over 30 years old and had a higher level of education. Only 47% of women in the maternity unit had skin-to-skin contact, while 73% stayed in the room with their baby. In 89% of women, the first breastfeeding occurred within the first hour after birth. The greatest assistance during breastfeeding was provided to mothers by healthcare personnel (94%).</p><p><strong>Conclusion: </strong>Continuous education of healthcare professionals and raising public awareness about the importance of breastfeeding must be a priority for every society.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"36 4","pages":"300-304"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11830228/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143443115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Seroprevalence of SARS-COV-2 Antibodies Associated with the Use of Personal Protective Equipment in Healthcare Workers.","authors":"Amela Dubinovic-Rekic, Nurka Pranjic","doi":"10.5455/msm.2024.36.222-228","DOIUrl":"10.5455/msm.2024.36.222-228","url":null,"abstract":"<p><strong>Background: </strong>Hypothetically, PPE played an estimated influential role in preventing SARS-CoV-2 transmission among HCWs before immune-prophylaxis by vaccination in BH. Objective: This research aims to determine the relationship between PPE use and the serological response to SARS-COV-2 among HCWs.</p><p><strong>Methods: </strong>The sample contained 127 COVID-19 outpatients with an average age of 43.5 ± 10.8, 66% women, and 80 (63%) health workers as the study group (37% non-medical workers as a control subjects). The created questionnaire collected sociodemographic data on comorbidity or not, application of PPE, and severity of the clinical picture of COVID-19 infection.</p><p><strong>Results: </strong>All subjects were monitored for the dynamics of antibodies, separately for IgM- and Ig-G three times, repeated every 3 months (only three before immuno-prophylaxis by vaccinations). A serological investigation of subjects' blood was collected by trained medical staff in vacutainers with a clotting activator to obtain the subjects' serum centrifuged, separated, and tested on the AFIAS 6 COVID-19 apparatus. Healthcare workers who did not wear goggles had significantly higher IgM antibody levels than HCWs who use them [F=9.359 (1, 102), p=.003, partial η2=.084]. Also, HCWs who did not use a visor had significantly higher IgM nucleocapsid antibody titer than those who used it daily or occasionally [F=4.790 (1, 102), p=.031, partial η2=.045]. Increase SARAS-COV-2 IgM titer three, six, or nine months after past COVID-19 infection and before vaccination.</p><p><strong>Conclusion: </strong>It presents a new acute or recent asymptomatic infection in our HCWs and unrecognized COVID-19. This implies considerable source and unrecognized risk of transmission of the SARS-COV-2 virus, and among HCWs, COVID-19 is an infectious disease with a high prevalence rate.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"36 3","pages":"222-228"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11693126/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142924382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Challenges of Occupational Health and Safety Management in Healthcare Institutions in Kosovo.","authors":"Albina Xhemaili Kelmendi, Naser Rugova, Doncho Donev","doi":"10.5455/msm.2024.36.149-154","DOIUrl":"10.5455/msm.2024.36.149-154","url":null,"abstract":"<p><strong>Background: </strong>Occupational health and safety (OHS) in healthcare institutions are crucial for the well-being of healthcare workers who are exposed to numerous risks in their working environment. In Kosovo, where healthcare institutions operate under resource constraints, understanding the challenges of OHS management challenges is vital for developing effective strategies.</p><p><strong>Objective: </strong>This study aims to explore the challenges of OHS management in Kosovo's healthcare system, focusing on three levels of healthcare provision in both the public and private sectors. The study aims to identify gaps in policies, practices, and infrastructure that affect the safety of healthcare workers and propose actionable recommendations.</p><p><strong>Methods: </strong>A qualitative research design was used, involving 191 healthcare professionals from primary, secondary, and tertiary levels of healthcare. Participants were randomly selected from public and private institutions. Data collection methods included semi-structured interviews and focus group discussions, ensuring a comprehensive understanding of OHS practices, perceptions, and barriers. Thematic analysis was used to identify key patterns and findings.</p><p><strong>Results: </strong>The findings revealed significant challenges in OHS management, including inadequate infrastructure, lack of personal protective equipment, insufficient training, and weak enforcement of regulations. Healthcare professionals reported high exposure to biological, chemical, and physical hazards, compounded by limited institutional support. Private sector facilities demonstrated slightly better resource availability but faced similar regulatory gaps.</p><p><strong>Conclusion: </strong>The study highlights critical deficiencies in OHS management in Kosovo's health system, posing risks to health professionals and the overall service quality. Addressing these challenges requires a multifaceted approach, including policy reforms, enhanced enforcement mechanisms, capacity-building initiatives, and improved resource allocation. Strengthening OHS management is essential for safeguarding the health workforce and ensuring sustainable healthcare delivery in Kosovo.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"36 2","pages":"149-154"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11662998/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142879185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Heart Failure After Acute Coronary Syndrome: A Comprehensive Analysis from Bosnia and Herzegovina.","authors":"Armin Sljivo, Amel Dzanic, Lana Lekic, Aladin Altic, Arian Abdulkhaliq","doi":"10.5455/msm.2024.36.110-114","DOIUrl":"10.5455/msm.2024.36.110-114","url":null,"abstract":"<p><strong>Background: </strong>The incidence of HF following ACS remains unacceptably high at discharge and several identified risk factors contribute to the development of HF in this context.</p><p><strong>Objective: </strong>This study investigated the prevalence and clinical significance of HF in patients admitted to the Clinic for Heart, Blood Vessels, and Rheumatic Diseases at the Clinical Center of the University of Sarajevo following ACS.</p><p><strong>Methods: </strong>This retrospective observational study was conducted at the Clinic for Heart, Blood Vessels, and Rheumatic Diseases of the Clinical Center of the University of Sarajevo between February 1^st and April 1^st, 2023, involving patients who were admitted because of ACS.</p><p><strong>Results: </strong>Patients with HFrEF were significantly (p=0.034) older (70.0 (62.0;76.0) vs 67.0 (57.5;75.0)), had (p=0.046) higher median score of LDH (321.5 (222.3; 501.5) vs. 256.0 (200.0; 420.0)), fibrinogen (p=0.047) (4.5 (3.2; 5.1) vs 3.6 (2.8; 5.0)), and NT-proBNP (p<0.001) (3705.0 (2500.0; 12559.5) vs. 500.0 (275.0; 333.0)), had enlarged left atrium diameter (3.9 (3.4; 4.4) vs 3.6 (3.1; 4.1)), enlarged left ventricular diameter both in diastole (5.1 (4.5; 5.8) vs 4.6 (4.1; 5.1)) and systole (3.7 (3.2; 4.1) vs 3.5 (3.1; 3.7)), thinner interventricular septum diameter both in diastole (1.1 (1.0; 1.2) vs 1.2 (1.1; 1.3)) and systole (1.3 (1.2; 1.5) vs. 1.4 (1.3; 1.5)) and elevated right ventricular systolic pressure (37.0 (30.0; 47.5) vs. 35.0 (28.0; 40.0 )) compared to patients without HFrEF. Severe mitral regurgitation was more observed in group of patients with HFrEF (p<0.001).</p><p><strong>Conclusion: </strong>HFrEF patients showed a 40% incidence of post-ACS, had elevated LDH, fibrinogen, and NT-proBNP levels, along with distinct echocardiographic differences, including enlarged heart chambers and higher mitral regurgitation rates following ACS. Early HF risk factor management is crucial for optimizing outcomes in ACS patients.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"36 2","pages":"110-114"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11663006/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142879212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}