Materia socio-medica最新文献

{"title":"Public Awareness of Corticosteroid Use and Side Effects: a Cross-Sectional Study from Jordan.","authors":"Sufian M Rifaei, Shahd Etoom, Suzan Adel Hanandeh, Sara Haj Ali, Aroob Mohammad Alzboon, Mohammad Dakhil Al-Jaraideh, Shatha Aktham, Kamal Khaled Moh'd Hamad, Mohamad Alharoun, Ahed J Alkhatib","doi":"10.5455/msm.2025.37.24-31","DOIUrl":"10.5455/msm.2025.37.24-31","url":null,"abstract":"<p><strong>Background: </strong>Corticosteroid usage is very widespread these days. However, the way corticosteroids are administered, the side effects of the drug and the risks associated with its usage are not widely known.</p><p><strong>Objective: </strong>The authors evaluated the responses of a diverse group who were aware of the methods of corticosteroid administration, side effects and information provided by the health care provider. To assess the awareness level and identify the gaps in knowledge descriptive statistics were used.</p><p><strong>Methods: </strong>The study was a cross sectional online survey conducted during July and December of 2024 using non-probability convenience sampling. A collection of queries were used to test knowledge of steroids as well as its effects. The sample included Jordanians aged 18 and above. The data was analyzed using logistic regression and chi-square with the SPSS (version 27).</p><p><strong>Results: </strong>From the participants, it was seen that 39.8% used corticosteroids. The most recognized were the oral (81%) and intravenous (60.9%). Most commonly noticed side effects were weight gain (81%) and mood swings (45.9%), rare ones being anemia (7%) and epilepsy (4.3%) were less known. There was high awareness about corticosteroid use in respiratory illnesses like asthma (71%) and autoimmune conditions like rheumatoid disease (64%), but awareness about their use in metabolic and oncological diseases was limited. Only 40.9% of participants said that side effects info was provided to them.</p><p><strong>Conclusion: </strong>There were significant gaps in community awareness which might compromise the therapeutic utility of corticosteroids.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"37 1","pages":"24-31"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11910899/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143652872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Frequency of Fals and Degree of Diability in Stroke Patients.","authors":"Zikrija Dostovic, Nermin Mesic, Mirza Moranjkic, Hasad Imamovic, Suljo Kunic, Denisa Salihovic, Kenan Galijasevic","doi":"10.5455/msm.2025.37.164-168","DOIUrl":"10.5455/msm.2025.37.164-168","url":null,"abstract":"<p><strong>Background: </strong>Stroke patients have significant disability and an increased risk of falling.</p><p><strong>Objective: </strong>To determine the incidence of falls and the degree of disability in stroke patients and to determine the correlation of falls with the degree of disability.</p><p><strong>Methods: </strong>This is a prospective study of 100 stroke patients confirmed by computed tomography and magnetic resonance imaging of the brain. We used a demographic questionnaire together with the Glasgow Coma Scale, Stroke Assessment Scale, Rankin Scale and Morse Scale to collect data and analyzed them using SPSS 17, including statistical measures, including Pearson correlation.</p><p><strong>Results: </strong>Hemorrhagic stroke patients had a higher incidence of falls (p = 0.06). There was no difference in the incidence of falls according to the gender of the patients (p = 0.07). Older people had a higher frequency of falls, and women and patients with hemorrhagic stroke had a higher risk of falling (p = 0.2). Patients with a stroke in the area of the anterior circulation were statistically significantly more disabled (p < 0.05). A weak positive correlation was calculated between the frequency of falls of patients after stroke and the degree of disability (r = 0.08, n = 94, p = 0.4). Stroke patients who also had atrial fibrillation as a comorbidity had a statistically significantly higher frequency of falls compared to patients with other comorbidities (p = 0.02).</p><p><strong>Conclusion: </strong>Patients with hemorrhagic stroke have a higher frequency of falls. Women, elderly people, patients with a stroke in the area of the anterior circulation and with atrial fibrillation as a comorbidity are statistically significantly more disabled after a stroke. There is a positive correlation between the frequency of falls in patients after a stroke and the degree of disability.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"37 2","pages":"164-168"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12212237/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144556311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New Anticoagulant Therapy as a Treatment for Pulmonary Thromboembolism in Patients During the COVID-19 Epidemic.","authors":"Amar Terzimehic, Muhamed Skomorac, Lejla Hindija, Elma Kuduzovic","doi":"10.5455/msm.2025.37.144-148","DOIUrl":"10.5455/msm.2025.37.144-148","url":null,"abstract":"<p><strong>Background: </strong>Pulmonary embolism is a frequent, serious and life-threatening complication that represents the embolization of mostly thrombotic material into the pulmonary arteries, with complete or partial occlusion of one or more of its branches.</p><p><strong>Objective: </strong>To analyze the effectiveness of new anticoagulants (NOAC) in the long-term treatment of pulmonary embolism (PE) in patients with and without COVID-19.</p><p><strong>Methods: </strong>Retrospective and descriptive analysis based on data from medical records in the period 2021-2023. from the Zenica Cantonal Hospital.</p><p><strong>Results: </strong>Data were collected from 160 respondents, of which 33 (20.6%) were COVID-19 positive and 127 (79.4%) were not. Subjects with COVID-19 in 12 (36.4%) cases had reference D-dimer values, while 21 (63.6%) had elevated values. 9.1% had elevated platelet values, 78.8% had reference values, and 12.1% had decreased values. Among subjects without COVID-19, 50 (39.4%) had reference values of D-dimer, while 77 (60.6%) had an increase. 1 (0.8%) of subjects had decreased platelet values, 118 (92.9%) had reference values, and 8 (6.3%) had increased platelet values. No subjects with decreased D-dimer values were recorded.</p><p><strong>Conclusion: </strong>DOAC therapy showed equal efficacy in the long-term treatment of pulmonary embolism in both study groups, regardless of whether the subjects had COVID-19 or not.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"37 2","pages":"144-148"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12212239/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144556313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient Experience of Hemodialysis in a Nephrology Hospital in Vietnam.","authors":"Tuan Ngo Tri, Son Dao Anh, Dat Le Minh, Lap Nguyen Thi, Long Nguyen Hoang, Giang Kim Bao","doi":"10.5455/msm.2025.37.117-124","DOIUrl":"10.5455/msm.2025.37.117-124","url":null,"abstract":"<p><strong>Background: </strong>Assessing patient experiences is essential for evaluating hospital quality.</p><p><strong>Objective: </strong>This study aimed to describe the experiences of hemodialysis patients at Hanoi Nephrology Hospital in 2023 and identify several factors related to patient experience.</p><p><strong>Methods: </strong>A cross-sectional study was conducted in 2023 among 401 patients at the Hemodialysis department of the Hanoi Nephrology Hospital. The study utilized a structured questionnaire titled \"In-Center Hemodialysis Consumer Assessment of Healthcare Providers and Systems (ICH CAHPS)\" to conduct face-to-face interviews with the selected patients. Logistic regression analysis was applied to identify several factors associated with patient experiences.</p><p><strong>Results: </strong>Overall, patients reported positive experiences, particularly in their interactions with nephrologists. The highest satisfaction (78%) was for updates on treatment information from other doctors. Positive experiences were more likely to be reported by patients aged 55-64 years (versus. ≥75 years), having health insurance or other insurance (versus. No insurance), and having middle education (versus. Lower education). Living 15-30 km from a dialysis center and being a business traders increased satisfaction.</p><p><strong>Conclusion: </strong>This study emphasized the necessity of improving communication and patient education in hemodialysis care, specifically concerning treatment options. It recommended targeted interventions and additional research to enhance the patient experience and the quality of care in Vietnam's hemodialysis centers.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"37 2","pages":"117-124"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12212238/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144556314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical and Paraclinical Characteristics and Predictive Factors of Chronic Obstructive Pulmonary Exacerbation.","authors":"Hoang Thuy, Nguyen Dinh Tien, Nguyen Thi Huong Giang, Nguyen Thi Nguyet, Nguyen Ngoc Nghia, Tran Thi Ly","doi":"10.5455/msm.2025.37.32-36","DOIUrl":"10.5455/msm.2025.37.32-36","url":null,"abstract":"<p><strong>Background: </strong>Chronic obstructive pulmonary disease (COPD) is a common global condition, yet real-world data on exacerbations in Vietnamese patients remains limited. This highlights the need for further exploration of clinical complexities in this population.</p><p><strong>Objective: </strong>The aim of this study was to characterize the clinical and paraclinical features of COPD and identify predictors of exacerbation.</p><p><strong>Methods: </strong>A cross-sectional, prospective study was conducted on 180 inpatients at Vietnam National Lung Hospital from January 2016 to June 2021. Clinical and paraclinical data were collected.</p><p><strong>Results: </strong>The mean patient age was 69.38 ± 9.40 years, with 92.8% male. Common symptoms included dyspnea (97.8%), cough (85.6%), and expectoration (80.0%). GOLD stage distribution was: GOLD III (53.7%), GOLD IV (29.3%), and GOLD II (17.0%). Significant predictors of exacerbation included smoking (OR=2.79), comorbidities (OR=3.95), increased dyspnea (OR=14.83), increased sputum (OR=3.13), decreased alveolar murmur (OR=4.11), wheezing (OR=2.70), white blood cell count ≥10 G/L (OR=4.79), GOLD group D (OR=9.75), and FEV1 <30% (GOLD IV) (OR=7.51) (p < 0.05).</p><p><strong>Conclusion: </strong>Clinical and paraclinical predictors can aid in forecasting and mitigating COPD exacerbations.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"37 1","pages":"32-36"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11910905/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143652473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synergistic Effects of Hypoxia-Preconditioned Mesenchymal Stem Cells Secretome and Alkaline Water in Alleviating Oxidative Stress and Inflammation in Type 2 Diabetic Rats.","authors":"Irni Nasution, Agung Putra, Eko Setiawan","doi":"10.5455/msm.2024.37.4-10","DOIUrl":"10.5455/msm.2024.37.4-10","url":null,"abstract":"<p><strong>Background: </strong>Chronic inflammation and oxidative stress are central to the pathophysiology of Type 2 Diabetes Mellitus (T2DM), contributing to the progression of metabolic dysfunction and related complications.</p><p><strong>Objective: </strong>The aim of this study was to explore the therapeutic potential of combining hypoxia-preconditioned mesenchymal stem cell SH-MSC with alkaline water in a T2DM rat model.</p><p><strong>Methods: </strong>T2DM was induced in Wistar rats through a high-fat diet (HFD) followed by streptozotocin (STZ) administration. A total of 30 healthy male Wistar rats were randomly assigned to five groups: healthy control, T2DM, T2DM + Metformin, T2DM + SH-MSC, and T2DM + SH-MSC + alkaline water.</p><p><strong>Results: </strong>The combination of SH-MSC and alkaline water significantly reduced malondialdehyde (MDA) levels, a key indicator of lipid peroxidation, and suppressed the expression of p65 mRNA, a crucial component of the NF-κB signaling pathway. Notably, the most pronounced reduction in p65 mRNA expression was observed in the group receiving both SH-MSC and alkaline water, suggesting a synergistic effect in mitigating oxidative stress and inflammation.</p><p><strong>Conclusion: </strong>These findings highlight the potential of SH-MSC and alkaline water as a novel therapeutic strategy for alleviating T2DM.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"37 1","pages":"4-10"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11910908/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143652881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Abdominal Tuberculosis in a Young Female Immigrant-\"the Great Masquerader\" in a Nonendemic Country-a Case Report and Literature Review.","authors":"Ana Dimova, Rajko Fures, Janja Konjevod, Zlatko Hrgovic, Sanja Malinac Malojcic, Bojana Kranjcec","doi":"10.5455/msm.2025.37.169-174","DOIUrl":"10.5455/msm.2025.37.169-174","url":null,"abstract":"<p><strong>Background: </strong>Tuberculosis (TB), primarily recognized as a pulmonary disease, can manifest in various extrapulmonary forms, with abdominal tuberculosis (ATB) being one of the most common. Abdominal tuberculosis is one of the diseases known as \"the great imitator\" - it can mimic the clinical presentation of various diseases that are more common, such as appendicitis, acute cholecystitis, colitis, and some malignant diseases such as colon or stomach neoplasms. Diagnosis of ATB is often delayed, especially if a clinician in a nonendemic country does not include ATB in the differential diagnosis. Given the rising migration of people from the endemic to the nonendemic countries, we believe it is mandatory to raise consciousness about this clinical entity, as well as to lower a threshold to include ATB in the differential diagnosis.</p><p><strong>Objective: </strong>We present a case of a 31-year-old patient from Nepal, who was admitted through the emergency department of General Hospital Zabok, Croatia, with signs of acute abdomen, later successfully diagnosed and treated for ATB.</p><p><strong>Case presentation: </strong>We also deliver a brief literature review, summarizing the epidemiology, clinical presentation, diagnostic and therapeutic algorithms for ATB. Migrations are inevitably changing the vaccination status and epidemiological risks of any host country.</p><p><strong>Conclusion: </strong>Medical personnel should keep upgrading and revising their knowledge of the \"usual suspects\" whilst differentially diagnosing both immigrants and non-immigrants, in order to make timely and good quality diagnosis and treatment.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"37 2","pages":"169-174"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12212218/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144556277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Depth Perception and Intraocular Differences in Visual Acuities Among Older Spectacle Wearers.","authors":"Ivana Mravicic, Selma Lukacevic, Ante Barisic, Sudi Patel, Alma Biscevic, Melisa Ahmedbegovic-Pjano, Nikica Gabric","doi":"10.5455/msm.2025.37.37-42","DOIUrl":"10.5455/msm.2025.37.37-42","url":null,"abstract":"<p><strong>Background: </strong>Falls impose a heavy financial burden on society, and the incidence is age-related. The correction of refractive errors has been mooted as a valuable procedure to prevent falls. However, depth perception, estimated by stereo acuity tests, is reduced in the older population and has been cited as contributing to the higher incidence of falls in the elderly.</p><p><strong>Objective: </strong>To explore the clinical relationship between age, interocular differences in the corrected distance and near logMAR visual acuities, refractive errors, axial (eyeball) lengths, pupil sizes, and higher-order ocular aberrations (HOAs) on clinical measures of stereoacuity and aniseikonia in asymptomatic presbyopic habitual spectacle wearers.</p><p><strong>Methods: </strong>Total amount of 91 subjects underwent clinical assessment of i) subjective refractive error, ii) stereoacuity at 6m and 40cm (Randot Stereotests), iii) aniseikonia at 6m (Awaya test along vertical and horizontal meridian) iv) higher order aberrations (Hartman-Shack aberrometer) v) eyeball length and pupil size (IOL master 700). The Pythagorean theorem was applied to each pair of aniseikonia values to calculate the resultant aniseikonia (AR).</p><p><strong>Results: </strong>Mean (±sd,95%CI) age of the subjects was 56.2years (±8.10,54.6-57.9). Root mean square (RMS) interocular differences (±sd,95%CI) in spherical refractive errors, axial lengths and pupil sizes were 0.66D(±0.93,0.47-0.85), 0.24mm (±0.33,0.17-0.31), 0.15mm (±0.11,0.12-0.17). The median (mode, interquartile range) values for AR were 2.8(1.0,1.3-4.0). Significant correlations (p<.01) were revealed between: a) log distance stereoacuity (y1), age (x1) and RMS difference in the corrected distance logMAR visual acuity (x2). b) log near stereoacuity (y2), RMS differences in the corrected distance (x2) and near visual acuities (x3). These key associations are best described by: y1=0.011x1+1.101x2+1.553 (r² =0.169, n=91); y2=1.715x2+1.883x3+1.725 (r² = 0.239, n=91).</p><p><strong>Conclusion: </strong>Stereoacuity is age-related, influenced by interocular differences in the corrected visual acuities but not related to interocular differences in pupil sizes, HOAs or clinical measures of aniseikonia in older habitual spectacle wearers. Assessment of stereoacuity and aniseikonia, in older persons is useful when advising to prevent accidental mis-location and falls.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"37 1","pages":"37-42"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11910907/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143652798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Posterior Pericardiotomy and Its Impact on Clinical Outcomes in Off-Pump Coronary Artery Bypass Grafting Complications.","authors":"Alen Karic, Ekrema Mujaric, Alma Krajnovic, Ervin Busevac, Tarik Selimovic, Amar Milaimi, Armin Sljivo","doi":"10.5455/msm.2025.37.159-163","DOIUrl":"10.5455/msm.2025.37.159-163","url":null,"abstract":"<p><strong>Background: </strong>Posterior pericardiotomy has been proposed as a preventive strategy against postoperative pericardial effusion and cardiac tamponade in patients undergoing coronary artery bypass grafting (CABG). However, data regarding its clinical outcomes and potential associations with postoperative complications remain limited.</p><p><strong>Objective: </strong>To evaluate intraoperative and postoperative outcomes in patients undergoing off-pump CABG with concomitant posterior pericardiotomy, and to assess potential associations between perioperative variables and the development of common postoperative complications.</p><p><strong>Methods: </strong>This retrospective study included 38 patients who underwent off-pump CABG with posterior pericardiotomy. Demographic and clinical characteristics, procedural details, postoperative complications, and outcomes were analyzed. Associations between operative time, comorbidities (sex, diabetes mellitus, smoking), and postoperative complications such as atrial fibrillation, pleural and pericardial effusions, and drainage volume were statistically evaluated using chi-square and correlation analysis.</p><p><strong>Results: </strong>The study cohort had a mean age of 66.64 ± 7.28 years, with 68.1% male patients. Arterial hypertension was present in all patients, diabetes mellitus in 44.7%, and prior myocardial infarction in 65.7%. The mean left ventricular ejection fraction was 42.86 ± 10.21%, and triple-vessel disease was observed in 63.2% of patients. All patients underwent off-pump CABG. The mean operative time was 254.31 ± 59.04 minutes. Postoperative complications included new-onset atrial fibrillation in 15.7% of patients, pleural effusion in 42.1%, and pericardial effusion in 10.5%. No cases of cardiac tamponade were reported. A significant association was found between smoking and new-onset atrial fibrillation (p = 0.050), while no significant associations were observed between sex or diabetes and postoperative complications. Operative time was not significantly associated with pericardial or pleural effusion, nor with drainage volume. Complete recovery was observed in all 100.0% of patients.</p><p><strong>Conclusion: </strong>Posterior pericardiotomy performed during off-pump CABG was associated with a low incidence of pericardial effusion and no occurrence of cardiac tamponade. The procedure appears to be safe and may contribute to favorable postoperative outcomes. Smoking may be a risk factor for new-onset atrial fibrillation, warranting further investigation.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"37 2","pages":"159-163"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12212279/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144556315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and Predictors of Chronic Rhinosinusitis Among Factory Workers: an Occupational Health Perspective.","authors":"Nguyen Quang Hung, Truong Quang Nguyen","doi":"10.5455/msm.2025.37.98-105","DOIUrl":"10.5455/msm.2025.37.98-105","url":null,"abstract":"<p><strong>Background: </strong>Health-related quality of life is a major issue among patients with multiple sclerosis (MS). Chronic rhinosinusitis (CRS) poses a significant occupational health concern, particularly among factory workers exposed to environmental irritants such as cement dust.</p><p><strong>Objective: </strong>To determine the prevalence of CRS among Vietnamese cement factory workers and to identify associated demographic, occupational, and environmental risk factors.</p><p><strong>Methods: </strong>A cross-sectional study was conducted from June 2023 to June 2024 at the Hai Phong Cement Factory, involving 1,054 workers directly exposed to cement dust. CRS diagnosis followed Rosenfeld's clinical criteria, including symptom duration, endoscopic findings, and imaging results. Data on demographic, occupational, and environmental characteristics were collected through structured interviews and clinical assessments. Logistic regression analyses identified predictors of CRS.</p><p><strong>Results: </strong>The prevalence of CRS was 8.92% (n=94). Significant risk factors included co-existing ear, nose, and throat (ENT) diseases (OR: 4.67, 95% CI: 2.59-8.41, p<0.001), regular mask usage (OR: 1.88, 95% CI: 1.14-3.12, p=0.013), and exposure to carbon monoxide (CO) (OR: 2.78, 95% CI: 1.42-5.44, p=0.003). Protective factors included employment in electrical workshops (OR: 0.41, 95% CI: 0.21-0.77, p=0.006), vocational training (OR: 0.53, 95% CI: 0.30-0.92, p=0.026), and advancing age (OR: 0.94, 95% CI: 0.90-0.98, p=0.004).</p><p><strong>Conclusion: </strong>CRS prevalence among factory workers highlights a critical occupational health challenge. Co-existing ENT diseases and exposure to CO significantly increase CRS risk, whereas protective factors such as vocational training and work in less dusty environments mitigate this risk.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"37 2","pages":"98-105"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12212221/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144556316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}