Materia socio-medica最新文献

{"title":"Medical, Surgical and Experimental Approaches to Acute Mesenteric Ischemia and Reperfusion.","authors":"Zoran Matkovic, Zoran Aleksic","doi":"10.5455/msm.2024.36.77-81","DOIUrl":"https://doi.org/10.5455/msm.2024.36.77-81","url":null,"abstract":"<p><strong>Background: </strong>Acute mesenteric ishemia(AMI) is a rare but very serious disease with high rate of mortality and morbidity. About 1-2% of all gastrointestinal disease is AMI. Mortality is about 60-80% and depends of time between starting of symptoms and establishing of diagnosis, type AMI, comorbidities. AMI is often in older population with coronary syndrom and atrial fibrilation. AMI may be occlusive(embolisatio arteriae mesentericae superior(AMS), or thrombosis of AMS, mesenterial vein thrombosis) and nonoclusive form(NOMI). NOMI is rising in critical ill patients in shock or sepsis. Pathophysiology of AMI is very complex and significant role in this proces has ischemia and also reperfusion. Reperfusion injury including oxidative stres, inflamation, infection. The best diagnostic approach is CT angiography but after high clinical suspicion on AMI. Patients have sudden, catastrophic abdominal pain, vomitus, bloody diarrhoea. Therapy is multidisciplinary-basic treatment(resuscitation with cristaloids, antibiotic, anticoagulans...), surgical treatment-resection necrotic segments of intestinum without anastomosis or endovascular treatment. In early phases conservative treatment is possible( vasodilatation, thrombolysis). In some countries there are Intestinal Stroke Centers (ISC) in which patients with AMI have better prognosis. Because of progressive nature of AMI( rapide worsening) rare are clinical study,but there are many experimental study on animal models. Most of experimental study investigate protective effects of some supstances on damage on intestinum and remote organs during ishemia and reperfusion.</p><p><strong>Objective: </strong>To present literature data of clinical and experimental study, describe experiments on animal models and mention supstances whit promising results in protective strategies during AMI.</p><p><strong>Methods: </strong>We analysed Pubmed by using mesh terms such as acute mesenteric ischemia, intestinal injury, reperfusion, experimental study, clinical and therapeutic approach. Results: Sudden abdominal pain resists on opioids analgetics, high rate of CRP, hyperlactatemia, increase of D dimer is enough for suspicion of AMI. Often is delayed in establishing of diagnosis of AMI. CT angiography has sensitivity of 94%. Pneumatosis is sign of necrosis of intestinal wall. Classical surgical approach is dominant, more than 70%,. Endovascular treatment became often last few years. Experimental studies investigate occlusion of AMS with atraumatic clamp, with schemia and reperfusion in different intervals Most animals models are on wistar male rats.</p><p><strong>Conclusion: </strong>AMI has still high rate of mortality. Better diagnostic and therapeutic principles (shorter interval between appearance of symptoms and starting of therapy, multidisciplinary approach, higher percent of endovascular procedures), could decrease mortality. Experimental studies on animal models may be succesfull in development of","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"36 1","pages":"77-81"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10999141/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140870518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of Sexual Education Programs for Adolescents With Autism and the Role of Parents in Providing Support.","authors":"Anastasia Panagiotakopoulou, Ilias Vasileiou, Dimitra V Katsarou","doi":"10.5455/msm.2024.36.155-159","DOIUrl":"10.5455/msm.2024.36.155-159","url":null,"abstract":"<p><strong>Background: </strong>Sexual education of adolescents with autism spectrum disorder (ASD) is a complex challenge, as the lack of specialized programs limits effective learning. Adolescents with ASD have difficulty understanding abstract concepts such as consent, personal boundaries and safety, which increases the risk of exploitation.</p><p><strong>Objective: </strong>This study seeks to examine the experiences and challenges parents face in providing sexuality education to their children with ASD, highlighting the need for programs that respond to the particular needs of these adolescents.</p><p><strong>Methods: </strong>The research was based on a qualitative methodology, using semi-structured interviews with 10 parents of adolescents with autism, aged 12-18 years. Thematic analysis of the data revealed important categories related to sexuality, consent, personal boundaries, and safety.</p><p><strong>Results: </strong>Parents face serious difficulties in communicating these issues with their children. The lack of specialized tools and limited support from the education system make it difficult to provide sex education. The need for practical examples and repeated teaching was emphasized.</p><p><strong>Conclusion: </strong>The research highlights the imperative to develop tailored sex education programs that will help adolescents with ASD understand critical concepts. Collaboration between parents, educators and health professionals is vital to strengthen sexuality education and protect adolescents from potential risks of exploitation.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"36 2","pages":"155-159"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11662999/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142879216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge, Attitudes, and Practices Regarding COVID-19 Vaccination Among Internally Displaced People in the Kurdistan Region of Iraq (KRG).","authors":"Arian Abdulkhaliq, Leopold Reiter, Ioannis Zeglis, Wisam Natour, Ialda Nassiri, Ines Rahouande","doi":"10.5455/msm.2024.36.120-125","DOIUrl":"10.5455/msm.2024.36.120-125","url":null,"abstract":"<p><strong>Background: </strong>Iraq has yet to establish and initiate any vaccination initiatives to address the ongoing COVID-19 outbreak and mitigate its spread and mortality.</p><p><strong>Objective: </strong>This study aimed to evaluate the existing knowledge, attitudes, and behaviors surrounding COVID-19 vaccination amid the third wave of the outbreak.</p><p><strong>Methods: </strong>This cross-sectional study utilized an anonymous online questionnaire, modeled after a study conducted in Bosnia and Herzegovina, to investigate COVID-19 vaccination attitudes and practices during the third wave of the outbreak in the country.</p><p><strong>Results: </strong>In total, 2744 subjects from 27 camp for Internally Displaced People (IDP camps) in the Kurdistan region of Iraq, mostly male 1642 (61.4%), either with no previous education 701 (26.2%) or with a primary school degree 973 (36.4%), married 1610 (60.2%) and since 2014 1540 (57.6%) stationaed in the IDP Camps were included in the study. Mean age of our sample was 35.2±12.9 ranging 18- 94 years. The mean knowledge test score for our sample was 6.9±3.7 with correct answer rates ranging 27.7-78.2%. Only 31 (1.2%) of subjects scored maximum points on the knowledge test score. In total 1170 (42.7%) subjects agreed that COVID-19 vaccination programs will prevail in a battle versus COVID-19, while 1592 (58.0%) agreed that everyone should be vaccinated against COVID-19. Regarding the vaccination rates, only 421 (15.3%) have already been vaccinated against COVID-19, while 1658 (62.7%) expressed interest to get vaccinated in the future.</p><p><strong>Conclusion: </strong>Our study sheds light on vaccination attitudes among IDP camps in the Kurdistan region of Iraq. Despite lower knowledge scores, willingness to vaccinate against COVID-19 is relatively high, likely due to limited access to vaccines, perceived risk of the disease, and trust in healthcare providers.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"36 2","pages":"120-125"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11663000/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142879263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Role of Modifying Risk Factors as Well as Body Mass Index, Waist Circumference and Hip to Waist Ratio as Anthropometric Indicators and Parameters of Obesity in the Occurence of Stroke.","authors":"Merita Tiric-Campara, Edina Djozic, Suljo Kunic, Amra Salkic, Amel Amidzic, Amira Skopljak","doi":"10.5455/msm.2024.36.137-142","DOIUrl":"10.5455/msm.2024.36.137-142","url":null,"abstract":"<p><strong>Background: </strong>Evaluated values of body mass index (BMI), waist circumeference (WC) and waist-to-hip ratio (WHR) increase the risk of stroke, but the extent to which this is mediated by hypertension, diabetes, lipid status, smoking and alcohol consumption is not fully understood.</p><p><strong>Objective: </strong>The aim of this research is to examine the influence of modifying and non-modifying factors as well as obesity defined through BMI, WC and WHR on the occurrence of stroke.</p><p><strong>Methods: </strong>A total of 440 subjects were included in the cohort divided in to two groups. The first group were patients with stroke and another without stroke. We investigate modifable factor for stroke (hypertension (HTA), lipid status, diabetes mellitus (DM), smoking, alcohol consumption, educational status) as well as WHR, BMI and WC as determinants for obesitiy.</p><p><strong>Results: </strong>The majority of respondents in both groups had a secondary level of education. Smoking and alcohol consumption were slightly more prevalent in the group without stroke, while HTA and DM were slightly more prevalent in the group with stroke, but without a statistically significant difference. The largest number of respodents without stroke had HDL cholesterol values in the range of optimal >1.5, 70.9%, while 35.5% of respodents with stroke had values in the risk range, as well as 32.3% in the high risk range. LDL cholesterol values were on average statistically significantly higher in the group of respodents with stroke - 3.77±1.29 compared to the values in respodents without stroke - 3.20±1.20. The largest WC had patients with a hemorrhagic stroke 96.4 ± 15.5 cm. The average BMI was slightly higher in the group of patients with embolic stroke (28.5 ± 2.8) compared to patients with hemorrhagic stroke (28.4 ± 5.9) and thrombotic stroke (28.1 ± 4, 2). WHR was almost identical in all three types of stroke.</p><p><strong>Conclusion: </strong>There is correlation between modifable risk factor and obesity in stroke occurence.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"36 2","pages":"137-142"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11663001/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142879331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigating the Interrelationships Between Obesity, Academic Achievement, Physical Activity, and Social Support Among Jazan University Students.","authors":"Omar Oraibi, Mohammed Somaili, Khaled Daghriri, Mohammed Alameer, Mohamed Arishi, Ali Sahli, Mohammed Haidar, Atiah Najmi, Faisal Otaif, Hanadi Abueishah, Bassem Oraibi, Abdulhameed Alhazmi, Luai Alhazmi","doi":"10.5455/msm.2024.36.59-64","DOIUrl":"https://doi.org/10.5455/msm.2024.36.59-64","url":null,"abstract":"<p><strong>Background: </strong>In developing and developed countries, the prevalence of overweight and obesity has grown. The college phase is a critical period during which healthy behaviors are learned through lifestyle and social environment. College students are prone to increased stress, negatively affecting their daily activities and academic performance.</p><p><strong>Objective: </strong>The general study objective was to investigate the prevalence of obesity among Jazan University students.</p><p><strong>Methods: </strong>This observational cross-sectional study used a pre-tested self-administered anonymous electronic questionnaire to evaluate the prevalence of obesity among 474 Jazan University students and its association with academic performance, physical activity, and social support. Data were analyzed using the Statistical Package for the Social Sciences, and associations between variables were assessed using the chi-square test.</p><p><strong>Results: </strong>Approximately 21% and 9.2% of the male and female students were obese, respectively, and the prevalence of obesity significantly differed between them. The use of one or more tobacco products was significantly associated with the prevalence of obesity (P < 0.001); the prevalence of obesity was substantially higher among the tobacco product users than among the non-users (35.3% vs. 14.4%). The presence of a morbidity was also significantly associated with the prevalence of obesity (P = 0.007); the prevalence of obesity was significantly higher among the students with at least one comorbidity than among the medically free students (28.8% vs. 14.9%). Conversely, obesity was not associated with academic performance and depression. Specifically, the grade point average was not affected across the academic years (P = 0.085 and P = 0.308, respectively).</p><p><strong>Conclusion: </strong>Obesity is significantly associated with male sex and the use of one or more tobacco products. This finding warrants the need for strategic and multidisciplinary plans at all levels to encourage healthy behaviors among college students, including an active, healthy lifestyle.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"36 1","pages":"59-64"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10999139/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140872587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Skopje Declaration on Scientific and Publishing Integrity in Biomedicine.","authors":"Dijana Plasheska Karanfilska, Valentin Mircheski, Doncho Donev, Gordana Ristovska, Nevzat Elezi, Vladimir Trajkovski, Ilija Gligorov","doi":"10.5455/msm.2024.36.236-239","DOIUrl":"10.5455/msm.2024.36.236-239","url":null,"abstract":"","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"36 3","pages":"236-239"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11693119/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142924385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unveiling the Nexus: Depressive Symptoms and Medication Adherence in Hypertensive Patients' Self-care: A Systematic Review.","authors":"Theofilos Stamoulis, Elena Dragioti, Mary Gouva, Stefanos Mantzoukas, Michael Κourakos","doi":"10.5455/msm.2024.36.65-72","DOIUrl":"https://doi.org/10.5455/msm.2024.36.65-72","url":null,"abstract":"<p><strong>Background: </strong>Hypertension, a significant public health concern, is frequently linked to emotional disorders like depression. Research shows a reciprocal link between depression and hypertension, potentially influencing patients' adherence to self-care routines.</p><p><strong>Objective: </strong>This systematic review aimed to examine the association between depressive symptoms and aspects of self-care, with a focus on medication adherence in individuals diagnosed with hypertension.</p><p><strong>Methods: </strong>Following PRISMA guidelines, a systematic review was conducted by searching PubMed, PsycINFO and Scopus until March 17, 2023. The included studies involved quantitative primary research conducted in English, focusing on adults (≥18 years) diagnosed with hypertension and experiencing depressive symptoms. Observational studies were assessed using the Newcastle-Ottawa Scale, and randomized controlled trials were evaluated using the revised Cochrane Risk of Bias Tool (RoB 2.0). Due to the great diversity of these studies, a narrative synthesis of the results was undertaken. Results: A total of 18 studies involving 6,131 people with hypertension, that met our eligibility criteria were ultimately included. The reported rates of depressive symptoms ranged from 4% to 43%. Of these studies, nine reported a statistically significant association, showcasing an adverse impact of depressive symptoms on medication adherence. The remaining nine did not confirm the above.</p><p><strong>Conclusion: </strong>This systematic review highlights the diverse body of research exploring depressive symptoms and medication adherence among individuals with hypertension. The review suggests a need for increased attention to self-care practices, particularly in relation to adherence to antihypertensive medication. However, it recommends the conduction of more robust longitudinal studies to comprehensively explore this relationship.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"36 1","pages":"65-72"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10999142/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140864266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"OHCA in Bosnia and Herzegovina: Before and During the COVID-19 Pandemic.","authors":"Armin Sljivo, Arian Abdulkhaliq, Ahmed Mulac, Vlado Lukic, Ivona Margeta, Marija Rako, Emira Kapisazovic","doi":"10.5455/msm.2024.36.4-9","DOIUrl":"https://doi.org/10.5455/msm.2024.36.4-9","url":null,"abstract":"<p><strong>Background: </strong>Out-of-hospital cardiac arrest (OHCA) refers to the cessation of mechanical cardiac activity outside healthcare facilities which requires prompt intervention and intensive resuscitative efforts. The COVID-19 pandemic has caused significant disruptions to OHCA systems-of-care, adversely affecting every component of the chain of survival.</p><p><strong>Objective: </strong>The objective of this study was to examine the potential impacts of the COVID-19 pandemic on OHCA events, to draw comparisons between the period before and during the COVID-19 pandemic.</p><p><strong>Methods: </strong>This cross-sectional study encompassed data pertaining to all OHCA incidents attended to by the Emergency Medical Service of Canton Sarajevo, covering the period from January 2017 to December 2022, before and during the COVID-19 pandemic.</p><p><strong>Results: </strong>During observed period, a total of 1418 [796 (56.1%) before and 622 (43.9%) during COVID-19 pandemic] OHCA events have occurred in Canton Sarajevo of which 297 (20.9 %) [180 (12.7%) before and 117 (8.2%) during COVID-19 pandemic] obtained ROSC. After a 30-day period following the ROSC) it was observed that the predominant outcome, accounting for 181 (12.7%) [106 (7.4%) before and 75 (5.2%) during COVID-19 pandemic] of cases, was a complete recovery. An examination before and during COVID-19 pandemic revealed a decline in OHCA during the year 2021 and 2022 when COVID-19 pandemic was at its highest in the country Being younger, quicker EMT response time and individuals with the initial rhythm of VF or VT were significantly associated with obtaining ROSC (p<0.05). Only 48 (3.3%) of 1418 OHCA events were assisted by bystanders There was no report of AED usage.</p><p><strong>Conclusion: </strong>In conclusion, our investigation highlights the impact of the COVID-19 pandemic on OHCA events in Canton Sarajevo, revealing a decrease in OHCA incidence and a reduction in cases achieving ROSC. Notably, EMT response time was shorter during the pandemic.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"36 1","pages":"4-9"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10999140/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140873015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Impact of Outdoor in Nature Mindfulness on the Mental Well-being of Children and Adolescents. A Mental Health and Cross-cultural Approach.","authors":"Alexandros Argyriadis, Emmanuel Kopanakis, Panagiotis Koutras, Konstantinos Louvaris, Antonia-Zoi Mammi, Maria Psychogiou, Dimitra Katsarou, Isabel Vieira, Olga Drakopoulou, Agathi Argyriadii","doi":"10.5455/msm.2024.36.73-76","DOIUrl":"https://doi.org/10.5455/msm.2024.36.73-76","url":null,"abstract":"<p><strong>Background: </strong>Mindfulness, originating from ancient meditation practices, has garnered substantial scientific interest in recent decades due to its potential to enhance various aspects of well-being. The rise of scientific interest in mindfulness has led to the development of Mindfulness-Based Stress Reduction (MBSR) and other mindfulness-based interventions (MBIs), which have demonstrated positive effects on stress reduction, emotional regulation, and cognitive flexibility.</p><p><strong>Objective: </strong>This study aimed to explore the characteristics and applications of mindfulness, investigate its impact on mental health, and assess the potential benefits of combining mindfulness with nature-based interventions in promoting the well-being of children and adolescents.</p><p><strong>Methods: </strong>This review draws from existing literature, scholarly articles, and empirical studies related to mindfulness, nature exposure, and their effects on mental health.</p><p><strong>Results: </strong>The results highlight the manifold benefits of mindfulness in different populations, including health professionals, patients, children, adolescents, and the general public. Mindfulness practice has been associated with notable reductions in stress, anxiety, and depression, and has shown positive effects on brain plasticity and cognitive functioning. Furthermore, the integration of mindfulness with exposure to natural environments holds potential for enhanced stress reduction and cognitive restoration.</p><p><strong>Conclusion: </strong>The findings underscore the potential of mindfulness as a cost-effective and accessible intervention to promote mental health across diverse age groups and settings. Further research should explore the specific mechanisms and long-term effects of this integrated approach to optimize its benefits.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"36 1","pages":"73-76"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10999151/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140870714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Manifestations of European Borreliosis on the Skin in Acute, Subacute and Chronic Disease.","authors":"Sajma Krkic-Dautovic, Adis Salihbegovic, Emina Dervisevic, Refet Gojak, Meliha Hadzovic-Cengic, Damir Duratbegovic, Nermin Mostarac, Jasmina Begic, Haroon Ahmed","doi":"10.5455/msm.2024.36.33-39","DOIUrl":"https://doi.org/10.5455/msm.2024.36.33-39","url":null,"abstract":"<p><strong>Background: </strong>Lyme borreliosis is a multisystemic infection caused by the spirochete Borrelia burgdorferi. Erythema migras is the main clinical marker of the disease.</p><p><strong>Objective: </strong>This study aimed was to investigate the frequency and clinical manifestations of European borreliosis on the skin, and to determine the significance of these findings for diagnosis and therapy.</p><p><strong>Methods: </strong>A retrospective-prospective clinical study of outpatients treated and monitored in a private clinic of an infectologist was conducted over nine years from to 2013-2021. The study was clinical, descriptive and analytical in nature.</p><p><strong>Results: </strong>In the investigated period, 509 (30.8%) patients with borreliosis symptoms were treated. EM in our patients occurred under the following conditions: a) ringed redness, b) redness of target cels and d) continuous round or oval redness of different sizes of individual redness, or multiple occurrences with primary dissemination. Skin changes with multiorgan chronic symptoms of borreliosis occurred in 67.7% of cases the including: walking redness of different shapes and sizes, pink borreliosis stretch marks, white borreliosis stretch marks, borreliosis palms and soles, psoriatic changes, Acrodermatitis chronica atrophicans, Scleroderma circumscripta-morphae, Erythema nodosum, Granuloma anulare and Lichen striatus et atrophicans. Of the 509 patients treated for borreliosis, 32.3% with multi-organ symptomatology had no skin changes.</p><p><strong>Conclusion: </strong>The skin manifestations of European borreliosis are multi-layered and Erythema migrans are basic, but not the only markers of the disease. 'Pink borreliose stretch marks, \"white borreliosis striae\", \"borreliosis palms or soles\", and intermittent redness accompanied by itching are unique markers for the diagnosis of chronic borreliosis, if they are manifested.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"36 1","pages":"33-39"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10999147/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140873988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}