Materia socio-medica最新文献

{"title":"New Anticoagulant Therapy as a Treatment for Pulmonary Thromboembolism in Patients During the COVID-19 Epidemic.","authors":"Amar Terzimehic, Muhamed Skomorac, Lejla Hindija, Elma Kuduzovic","doi":"10.5455/msm.2025.37.144-148","DOIUrl":"10.5455/msm.2025.37.144-148","url":null,"abstract":"<p><strong>Background: </strong>Pulmonary embolism is a frequent, serious and life-threatening complication that represents the embolization of mostly thrombotic material into the pulmonary arteries, with complete or partial occlusion of one or more of its branches.</p><p><strong>Objective: </strong>To analyze the effectiveness of new anticoagulants (NOAC) in the long-term treatment of pulmonary embolism (PE) in patients with and without COVID-19.</p><p><strong>Methods: </strong>Retrospective and descriptive analysis based on data from medical records in the period 2021-2023. from the Zenica Cantonal Hospital.</p><p><strong>Results: </strong>Data were collected from 160 respondents, of which 33 (20.6%) were COVID-19 positive and 127 (79.4%) were not. Subjects with COVID-19 in 12 (36.4%) cases had reference D-dimer values, while 21 (63.6%) had elevated values. 9.1% had elevated platelet values, 78.8% had reference values, and 12.1% had decreased values. Among subjects without COVID-19, 50 (39.4%) had reference values of D-dimer, while 77 (60.6%) had an increase. 1 (0.8%) of subjects had decreased platelet values, 118 (92.9%) had reference values, and 8 (6.3%) had increased platelet values. No subjects with decreased D-dimer values were recorded.</p><p><strong>Conclusion: </strong>DOAC therapy showed equal efficacy in the long-term treatment of pulmonary embolism in both study groups, regardless of whether the subjects had COVID-19 or not.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"37 2","pages":"144-148"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12212239/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144556313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient Experience of Hemodialysis in a Nephrology Hospital in Vietnam.","authors":"Tuan Ngo Tri, Son Dao Anh, Dat Le Minh, Lap Nguyen Thi, Long Nguyen Hoang, Giang Kim Bao","doi":"10.5455/msm.2025.37.117-124","DOIUrl":"10.5455/msm.2025.37.117-124","url":null,"abstract":"<p><strong>Background: </strong>Assessing patient experiences is essential for evaluating hospital quality.</p><p><strong>Objective: </strong>This study aimed to describe the experiences of hemodialysis patients at Hanoi Nephrology Hospital in 2023 and identify several factors related to patient experience.</p><p><strong>Methods: </strong>A cross-sectional study was conducted in 2023 among 401 patients at the Hemodialysis department of the Hanoi Nephrology Hospital. The study utilized a structured questionnaire titled \"In-Center Hemodialysis Consumer Assessment of Healthcare Providers and Systems (ICH CAHPS)\" to conduct face-to-face interviews with the selected patients. Logistic regression analysis was applied to identify several factors associated with patient experiences.</p><p><strong>Results: </strong>Overall, patients reported positive experiences, particularly in their interactions with nephrologists. The highest satisfaction (78%) was for updates on treatment information from other doctors. Positive experiences were more likely to be reported by patients aged 55-64 years (versus. ≥75 years), having health insurance or other insurance (versus. No insurance), and having middle education (versus. Lower education). Living 15-30 km from a dialysis center and being a business traders increased satisfaction.</p><p><strong>Conclusion: </strong>This study emphasized the necessity of improving communication and patient education in hemodialysis care, specifically concerning treatment options. It recommended targeted interventions and additional research to enhance the patient experience and the quality of care in Vietnam's hemodialysis centers.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"37 2","pages":"117-124"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12212238/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144556314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Public Awareness of Corticosteroid Use and Side Effects: a Cross-Sectional Study from Jordan.","authors":"Sufian M Rifaei, Shahd Etoom, Suzan Adel Hanandeh, Sara Haj Ali, Aroob Mohammad Alzboon, Mohammad Dakhil Al-Jaraideh, Shatha Aktham, Kamal Khaled Moh'd Hamad, Mohamad Alharoun, Ahed J Alkhatib","doi":"10.5455/msm.2025.37.24-31","DOIUrl":"10.5455/msm.2025.37.24-31","url":null,"abstract":"<p><strong>Background: </strong>Corticosteroid usage is very widespread these days. However, the way corticosteroids are administered, the side effects of the drug and the risks associated with its usage are not widely known.</p><p><strong>Objective: </strong>The authors evaluated the responses of a diverse group who were aware of the methods of corticosteroid administration, side effects and information provided by the health care provider. To assess the awareness level and identify the gaps in knowledge descriptive statistics were used.</p><p><strong>Methods: </strong>The study was a cross sectional online survey conducted during July and December of 2024 using non-probability convenience sampling. A collection of queries were used to test knowledge of steroids as well as its effects. The sample included Jordanians aged 18 and above. The data was analyzed using logistic regression and chi-square with the SPSS (version 27).</p><p><strong>Results: </strong>From the participants, it was seen that 39.8% used corticosteroids. The most recognized were the oral (81%) and intravenous (60.9%). Most commonly noticed side effects were weight gain (81%) and mood swings (45.9%), rare ones being anemia (7%) and epilepsy (4.3%) were less known. There was high awareness about corticosteroid use in respiratory illnesses like asthma (71%) and autoimmune conditions like rheumatoid disease (64%), but awareness about their use in metabolic and oncological diseases was limited. Only 40.9% of participants said that side effects info was provided to them.</p><p><strong>Conclusion: </strong>There were significant gaps in community awareness which might compromise the therapeutic utility of corticosteroids.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"37 1","pages":"24-31"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11910899/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143652872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Duffy Antigen Receptor for Chemokines (DARC) Polymorphisms and Susceptibility to Plasmodium Vivax Malaria in Sudan: a Case - Control Study.","authors":"Samar Ali Osman, Elshazali Widaa Ali, Elamin Abdelkarim Elamin, Osman Mansour","doi":"10.5455/msm.2025.37.276-280","DOIUrl":"10.5455/msm.2025.37.276-280","url":null,"abstract":"<p><strong>Background: </strong>Duffy-negative individuals were long considered resistant to Plasmodium vivax, yet emerging infections challenge this assumption, underscoring the need to examine Duffy antigen receptor for chemokines (DARC) gene polymorphisms and clarify evolving susceptibility patterns.</p><p><strong>Objective: </strong>This study investigated the association between DARC genetic variants and susceptibility to P. vivax infection to elucidate transmission patterns and explain the rising incidence of P. vivax infection in Sudan.</p><p><strong>Methods: </strong>A total of 405 participants were recruited for the study, including 202 patients with a confirmed diagnosis of P. vivax malaria and 203 blood donors serving as the control group. DNA was extracted from the peripheral blood, and DARC polymorphic variants were analyzed using polymerase chain reaction- sequence specific primer (PCR-SSP).</p><p><strong>Results: </strong>The study showed that the Duffy-negative homozygous genotype FYBES/FYBES was present in both P. vivax-infected patients and the control group; however, it was significantly more frequent in healthy blood donors. The frequencies of the homozygous FYB/FYB genotype and the two heterozygous genotypes FYB/FYA and FYB/FYBES were substantially higher among the patients with P. vivax malaria than in the control group. The homozygous genotype FYA/FYA was more frequent among P. vivax malaria patients, while the heterozygous genotype FYA/FYBES was more common in the control group; however, the differences were not statistically significant. The FYAES allele was not detected in either group.</p><p><strong>Conclusion: </strong>There was a potential association between FYA and FYB alleles and susceptibility to P. vivax infection. The FYBES allele confers partial resistance to P. vivax malaria, as some infected individuals were found to carry the homozygous Duffy-negative genotype (FYBES/ FYBES).</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"37 4","pages":"276-280"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12923281/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147273845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Saudi Adult's Knowledge of Pediatric Developmental Milestones.","authors":"Faisal Alqurashi, Renad Alsayari, Genan Ahmed Almajed, Sarah Mohammed Bubshait, Reem Abdulrahman Alateeq, Ghaida Ahmed Assiry, Mohammad Ghuwaizi Alharbi, Faisal Alharthi, Abdullah Sameer Alsaedi, Wajd Abdulaziz Alasmari","doi":"10.5455/msm.2025.37.191-204","DOIUrl":"10.5455/msm.2025.37.191-204","url":null,"abstract":"<p><strong>Background: </strong>Early recognition of developmental milestones is vital for timely detection of delays. While studies in Saudi Arabia have assessed parental awareness, little is known about the general adult population's knowledge.</p><p><strong>Objective: </strong>The aim of this study was to evaluate the awareness and knowledge of developmental milestones among adults in Saudi Arabia.</p><p><strong>Methods: </strong>A cross-sectional study was conducted from July to November 2024 using an online questionnaire in Arabic and English. The survey assessed knowledge across five devel-opmental domains. A total of 924 adults aged 18-65 years participated. Knowledge scores were categorized into high, moderate, and low levels. Data were analyzed with SPSS version 29, and associations with sociodemographic variables were tested.</p><p><strong>Results: </strong>Overall, 31% of participants demonstrated high knowledge, 44.8% moderate, and 24.2% low. Awareness was stronger for gross motor skills in older children but weaker for infant and early speech/language milestones. Only 43.3% recognized the expected vocabulary at 24 months, and many expressed uncertainty about early infancy mile-stones. Knowledge was significantly associated with gender, age, marital status, educa-tion, occupation, and income (p < 0.05). Informal sources, particularly family and friends, were the most common source of information, while healthcare professionals and formal resources were less utilized.</p><p><strong>Conclusion: </strong>Substantial gaps in developmental milestone knowledge exist among Saudi adults, especially regarding infant and speech/language development. Targeted public health education and greater involve-ment of healthcare providers are needed to strengthen awareness and support early in-tervention.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"37 3","pages":"191-204"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12858278/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146109297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ovarian Carcinoma Initially-presented as Cerebral Metastasis: Epidemiology, Pathology, and Outcomes.","authors":"Suhair Qudsieh, Omar Altal, Mohamed M Barbarawi, Zainab Albikawi, Lara Al Barbarawi, Abdelwahab Aleshawi","doi":"10.5455/msm.2025.37.236-242","DOIUrl":"10.5455/msm.2025.37.236-242","url":null,"abstract":"<p><strong>Background: </strong>An initial presentation of ovarian carcinoma with brain metastasis has been reported in the literature in a limited number of cases, as ovarian cancer rarely metastasizes to the brain.</p><p><strong>Objective: </strong>This study aims to a) Systematically review the literature to identify studies on ovarian carcinoma presenting initially as cerebral metastasis and b) to investigate cases of ovarian carcinoma that were initially presented with cerebral metastasis.</p><p><strong>Methods: </strong>A PRISMA-guided systematic review was conducted, coupled with a retrospective study at the King Abdullah University Hospital from 2005 to 2020. Two hundred sixty-three ovarian carcinoma cases were analyzed for the presence of brain metastasis, out of which 25 were positive for brain metastasis, and seven of them presented initially with neurological symptoms. Demographics, clinical features, histopathology, and treatments were identified.</p><p><strong>Results: </strong>Eight out of 215 studies conducted between 1999 and 2024 satisfied the criteria for ovarian cancer initially manifesting with neurological symptoms. In the retrospective analysis, 85% and 71% of patients, with a mean age of 41, exhibited headache and impaired vision. Serous cancer manifested in 58%, with solitary brain lesions observed in 71%; surgical intervention yielded improved outcomes. Multimodal treatments involving craniotomy, radiation, and chemotherapy resulted in a median survival of 18.7 months. Fertility drugs utilization was recorded in 57%, indicating a possible association with aggressive illness.</p><p><strong>Conclusion: </strong>This study illustrates that ovarian cancer presenting as brain metastases at its initial presentation is rare and should be considered in younger women with fertility drugs usage. Long-term risks of fertility drugs should be assessed as use increases. Multimodal therapy improves survival and results.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"37 3","pages":"236-242"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12858262/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146109323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-Term Case-Finding of Latent Tuberculosis Infection Among Household Contacts to Support Tuberculosis Elimination Efforts in Indonesia.","authors":"Bahtera Bindavid Purba, Ripando Jon Satria Sembiring, Friska Ernita Sitorus, Firdaus Fahdi, Dahlia Purba","doi":"10.5455/msm.2025.37.243-249","DOIUrl":"10.5455/msm.2025.37.243-249","url":null,"abstract":"<p><strong>Background: </strong>Indonesia reported the second-highest global burden of tuberculosis after India, with a 2.6% increase in cases from the previous year.</p><p><strong>Objective: </strong>This study aimed to evaluate case-finding of latent tuberculosis infection (LTBI) and differences in tuberculin induration diameters among household contacts of index patients, stratified by contact follow-up interval (1-180 months). Methods: A total of 240 index patients were recruited from four primary health cares in Simalungun District and assigned to four time interval groups in duration of 0-180 months. Tuberculin skin tests were administered to 912 contacts. Latent tuberculosis infection incidence was analyzed using proportion tests, and differences in induration diameter across time interval were tested using ANOVA (α = 0.05).</p><p><strong>Results: </strong>The overall latent tuberculosis infection incidence was 22.4% (95% CI: 19.2-26.1) across time intervals of 1-180 months, with rates of 10.7% for 1-6 months, 21.4% for 7-24 months, 30.2% for 25-60 months, and 28.0% for 61-180 months. Significant differences in induration diameter were observed between 1-6 months and 7-24 months (p < 0.01), 1-6 months and 25-60 months (p < 0.01), and 1-6 months and 61-180 months (p < 0.01).</p><p><strong>Conclusion: </strong>Increasing incidence of latent tuberculosis infection across time intervals of 0-180 months, indicating a rising potential for future active tuberculosis cases. This pattern reflects a progressive tuberculin conversion among household contacts, particularly between 0-6 and 7-24 months.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"37 3","pages":"243-249"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12858272/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146109325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical and Paraclinical Characteristics and Predictive Factors of Chronic Obstructive Pulmonary Exacerbation.","authors":"Hoang Thuy, Nguyen Dinh Tien, Nguyen Thi Huong Giang, Nguyen Thi Nguyet, Nguyen Ngoc Nghia, Tran Thi Ly","doi":"10.5455/msm.2025.37.32-36","DOIUrl":"10.5455/msm.2025.37.32-36","url":null,"abstract":"<p><strong>Background: </strong>Chronic obstructive pulmonary disease (COPD) is a common global condition, yet real-world data on exacerbations in Vietnamese patients remains limited. This highlights the need for further exploration of clinical complexities in this population.</p><p><strong>Objective: </strong>The aim of this study was to characterize the clinical and paraclinical features of COPD and identify predictors of exacerbation.</p><p><strong>Methods: </strong>A cross-sectional, prospective study was conducted on 180 inpatients at Vietnam National Lung Hospital from January 2016 to June 2021. Clinical and paraclinical data were collected.</p><p><strong>Results: </strong>The mean patient age was 69.38 ± 9.40 years, with 92.8% male. Common symptoms included dyspnea (97.8%), cough (85.6%), and expectoration (80.0%). GOLD stage distribution was: GOLD III (53.7%), GOLD IV (29.3%), and GOLD II (17.0%). Significant predictors of exacerbation included smoking (OR=2.79), comorbidities (OR=3.95), increased dyspnea (OR=14.83), increased sputum (OR=3.13), decreased alveolar murmur (OR=4.11), wheezing (OR=2.70), white blood cell count ≥10 G/L (OR=4.79), GOLD group D (OR=9.75), and FEV1 <30% (GOLD IV) (OR=7.51) (p < 0.05).</p><p><strong>Conclusion: </strong>Clinical and paraclinical predictors can aid in forecasting and mitigating COPD exacerbations.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"37 1","pages":"32-36"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11910905/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143652473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synergistic Effects of Hypoxia-Preconditioned Mesenchymal Stem Cells Secretome and Alkaline Water in Alleviating Oxidative Stress and Inflammation in Type 2 Diabetic Rats.","authors":"Irni Nasution, Agung Putra, Eko Setiawan","doi":"10.5455/msm.2024.37.4-10","DOIUrl":"10.5455/msm.2024.37.4-10","url":null,"abstract":"<p><strong>Background: </strong>Chronic inflammation and oxidative stress are central to the pathophysiology of Type 2 Diabetes Mellitus (T2DM), contributing to the progression of metabolic dysfunction and related complications.</p><p><strong>Objective: </strong>The aim of this study was to explore the therapeutic potential of combining hypoxia-preconditioned mesenchymal stem cell SH-MSC with alkaline water in a T2DM rat model.</p><p><strong>Methods: </strong>T2DM was induced in Wistar rats through a high-fat diet (HFD) followed by streptozotocin (STZ) administration. A total of 30 healthy male Wistar rats were randomly assigned to five groups: healthy control, T2DM, T2DM + Metformin, T2DM + SH-MSC, and T2DM + SH-MSC + alkaline water.</p><p><strong>Results: </strong>The combination of SH-MSC and alkaline water significantly reduced malondialdehyde (MDA) levels, a key indicator of lipid peroxidation, and suppressed the expression of p65 mRNA, a crucial component of the NF-κB signaling pathway. Notably, the most pronounced reduction in p65 mRNA expression was observed in the group receiving both SH-MSC and alkaline water, suggesting a synergistic effect in mitigating oxidative stress and inflammation.</p><p><strong>Conclusion: </strong>These findings highlight the potential of SH-MSC and alkaline water as a novel therapeutic strategy for alleviating T2DM.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"37 1","pages":"4-10"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11910908/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143652881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Abdominal Tuberculosis in a Young Female Immigrant-\"the Great Masquerader\" in a Nonendemic Country-a Case Report and Literature Review.","authors":"Ana Dimova, Rajko Fures, Janja Konjevod, Zlatko Hrgovic, Sanja Malinac Malojcic, Bojana Kranjcec","doi":"10.5455/msm.2025.37.169-174","DOIUrl":"10.5455/msm.2025.37.169-174","url":null,"abstract":"<p><strong>Background: </strong>Tuberculosis (TB), primarily recognized as a pulmonary disease, can manifest in various extrapulmonary forms, with abdominal tuberculosis (ATB) being one of the most common. Abdominal tuberculosis is one of the diseases known as \"the great imitator\" - it can mimic the clinical presentation of various diseases that are more common, such as appendicitis, acute cholecystitis, colitis, and some malignant diseases such as colon or stomach neoplasms. Diagnosis of ATB is often delayed, especially if a clinician in a nonendemic country does not include ATB in the differential diagnosis. Given the rising migration of people from the endemic to the nonendemic countries, we believe it is mandatory to raise consciousness about this clinical entity, as well as to lower a threshold to include ATB in the differential diagnosis.</p><p><strong>Objective: </strong>We present a case of a 31-year-old patient from Nepal, who was admitted through the emergency department of General Hospital Zabok, Croatia, with signs of acute abdomen, later successfully diagnosed and treated for ATB.</p><p><strong>Case presentation: </strong>We also deliver a brief literature review, summarizing the epidemiology, clinical presentation, diagnostic and therapeutic algorithms for ATB. Migrations are inevitably changing the vaccination status and epidemiological risks of any host country.</p><p><strong>Conclusion: </strong>Medical personnel should keep upgrading and revising their knowledge of the \"usual suspects\" whilst differentially diagnosing both immigrants and non-immigrants, in order to make timely and good quality diagnosis and treatment.</p>","PeriodicalId":94128,"journal":{"name":"Materia socio-medica","volume":"37 2","pages":"169-174"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12212218/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144556277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}